Amino acid dipepetide frequency for Myroides profundi

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	3.66AlaAla: 3.66 ± 0.07	0.532AlaCys: 0.532 ± 0.026	3.313AlaAsp: 3.313 ± 0.08	3.839AlaGlu: 3.839 ± 0.075	3.132AlaPhe: 3.132 ± 0.052	3.737AlaGly: 3.737 ± 0.063	1.064AlaHis: 1.064 ± 0.031	5.331AlaIle: 5.331 ± 0.08	4.896AlaLys: 4.896 ± 0.075	6.38AlaLeu: 6.38 ± 0.081	1.584AlaMet: 1.584 ± 0.037	3.352AlaAsn: 3.352 ± 0.07	1.782AlaPro: 1.782 ± 0.04	2.387AlaGln: 2.387 ± 0.047	1.894AlaArg: 1.894 ± 0.046	3.88AlaSer: 3.88 ± 0.061	3.64AlaThr: 3.64 ± 0.061	4.227AlaVal: 4.227 ± 0.083	0.53AlaTrp: 0.53 ± 0.023	2.65AlaTyr: 2.65 ± 0.053	0.0AlaXaa: 0.0 ± 0.0
Cys	0.402CysAla: 0.402 ± 0.021	0.104CysCys: 0.104 ± 0.012	0.396CysAsp: 0.396 ± 0.018	0.403CysGlu: 0.403 ± 0.019	0.428CysPhe: 0.428 ± 0.021	0.591CysGly: 0.591 ± 0.025	0.168CysHis: 0.168 ± 0.013	0.627CysIle: 0.627 ± 0.023	0.472CysLys: 0.472 ± 0.024	0.692CysLeu: 0.692 ± 0.028	0.142CysMet: 0.142 ± 0.011	0.361CysAsn: 0.361 ± 0.018	0.295CysPro: 0.295 ± 0.019	0.217CysGln: 0.217 ± 0.014	0.186CysArg: 0.186 ± 0.013	0.542CysSer: 0.542 ± 0.023	0.433CysThr: 0.433 ± 0.023	0.441CysVal: 0.441 ± 0.022	0.056CysTrp: 0.056 ± 0.007	0.318CysTyr: 0.318 ± 0.019	0.0CysXaa: 0.0 ± 0.0
Asp	3.227AspAla: 3.227 ± 0.063	0.388AspCys: 0.388 ± 0.018	2.477AspAsp: 2.477 ± 0.052	3.449AspGlu: 3.449 ± 0.059	3.219AspPhe: 3.219 ± 0.054	3.407AspGly: 3.407 ± 0.081	1.0AspHis: 1.0 ± 0.03	4.842AspIle: 4.842 ± 0.074	5.027AspLys: 5.027 ± 0.079	5.322AspLeu: 5.322 ± 0.08	1.17AspMet: 1.17 ± 0.034	3.313AspAsn: 3.313 ± 0.066	1.58AspPro: 1.58 ± 0.037	1.796AspGln: 1.796 ± 0.043	2.098AspArg: 2.098 ± 0.045	3.07AspSer: 3.07 ± 0.053	2.893AspThr: 2.893 ± 0.053	3.475AspVal: 3.475 ± 0.063	0.638AspTrp: 0.638 ± 0.023	3.128AspTyr: 3.128 ± 0.055	0.0AspXaa: 0.0 ± 0.0
Glu	4.264GluAla: 4.264 ± 0.08	0.365GluCys: 0.365 ± 0.02	3.65GluAsp: 3.65 ± 0.07	5.828GluGlu: 5.828 ± 0.102	2.85GluPhe: 2.85 ± 0.05	4.222GluGly: 4.222 ± 0.068	1.294GluHis: 1.294 ± 0.035	5.271GluIle: 5.271 ± 0.071	5.52GluLys: 5.52 ± 0.087	6.814GluLeu: 6.814 ± 0.082	1.666GluMet: 1.666 ± 0.042	3.888GluAsn: 3.888 ± 0.063	1.477GluPro: 1.477 ± 0.037	2.9GluGln: 2.9 ± 0.06	2.676GluArg: 2.676 ± 0.055	3.552GluSer: 3.552 ± 0.063	3.147GluThr: 3.147 ± 0.062	5.115GluVal: 5.115 ± 0.073	0.674GluTrp: 0.674 ± 0.022	3.048GluTyr: 3.048 ± 0.058	0.0GluXaa: 0.0 ± 0.0
Phe	2.837PheAla: 2.837 ± 0.057	0.445PheCys: 0.445 ± 0.021	3.153PheAsp: 3.153 ± 0.049	3.032PheGlu: 3.032 ± 0.057	2.634PhePhe: 2.634 ± 0.063	3.268PheGly: 3.268 ± 0.06	0.723PheHis: 0.723 ± 0.024	4.044PheIle: 4.044 ± 0.069	3.63PheLys: 3.63 ± 0.058	4.313PheLeu: 4.313 ± 0.074	1.168PheMet: 1.168 ± 0.029	3.009PheAsn: 3.009 ± 0.057	1.519PhePro: 1.519 ± 0.037	1.373PheGln: 1.373 ± 0.036	1.517PheArg: 1.517 ± 0.04	3.635PheSer: 3.635 ± 0.056	2.961PheThr: 2.961 ± 0.061	3.053PheVal: 3.053 ± 0.06	0.517PheTrp: 0.517 ± 0.025	2.294PheTyr: 2.294 ± 0.047	0.0PheXaa: 0.0 ± 0.0
Gly	4.062GlyAla: 4.062 ± 0.076	0.514GlyCys: 0.514 ± 0.02	3.371GlyAsp: 3.371 ± 0.069	3.861GlyGlu: 3.861 ± 0.068	3.215GlyPhe: 3.215 ± 0.058	4.309GlyGly: 4.309 ± 0.08	1.053GlyHis: 1.053 ± 0.032	5.139GlyIle: 5.139 ± 0.072	4.965GlyLys: 4.965 ± 0.082	5.513GlyLeu: 5.513 ± 0.073	1.701GlyMet: 1.701 ± 0.041	3.287GlyAsn: 3.287 ± 0.065	1.093GlyPro: 1.093 ± 0.036	2.098GlyGln: 2.098 ± 0.049	2.04GlyArg: 2.04 ± 0.052	3.691GlySer: 3.691 ± 0.062	3.831GlyThr: 3.831 ± 0.079	4.961GlyVal: 4.961 ± 0.074	0.666GlyTrp: 0.666 ± 0.025	3.091GlyTyr: 3.091 ± 0.057	0.0GlyXaa: 0.0 ± 0.0
His	0.956HisAla: 0.956 ± 0.029	0.18HisCys: 0.18 ± 0.014	0.849HisAsp: 0.849 ± 0.03	0.923HisGlu: 0.923 ± 0.034	1.097HisPhe: 1.097 ± 0.033	0.96HisGly: 0.96 ± 0.029	0.431HisHis: 0.431 ± 0.017	1.488HisIle: 1.488 ± 0.039	1.235HisLys: 1.235 ± 0.034	1.849HisLeu: 1.849 ± 0.043	0.292HisMet: 0.292 ± 0.018	1.08HisAsn: 1.08 ± 0.034	0.776HisPro: 0.776 ± 0.029	0.702HisGln: 0.702 ± 0.02	0.655HisArg: 0.655 ± 0.021	1.066HisSer: 1.066 ± 0.027	1.069HisThr: 1.069 ± 0.032	0.831HisVal: 0.831 ± 0.026	0.183HisTrp: 0.183 ± 0.013	0.926HisTyr: 0.926 ± 0.032	0.0HisXaa: 0.0 ± 0.0
Ile	5.571IleAla: 5.571 ± 0.069	0.62IleCys: 0.62 ± 0.023	5.024IleAsp: 5.024 ± 0.079	5.975IleGlu: 5.975 ± 0.079	3.175IlePhe: 3.175 ± 0.07	5.307IleGly: 5.307 ± 0.073	1.439IleHis: 1.439 ± 0.033	6.006IleIle: 6.006 ± 0.094	5.901IleLys: 5.901 ± 0.069	6.886IleLeu: 6.886 ± 0.094	1.507IleMet: 1.507 ± 0.039	4.583IleAsn: 4.583 ± 0.063	2.911IlePro: 2.911 ± 0.055	2.736IleGln: 2.736 ± 0.05	2.634IleArg: 2.634 ± 0.055	5.303IleSer: 5.303 ± 0.077	4.986IleThr: 4.986 ± 0.081	5.429IleVal: 5.429 ± 0.074	0.636IleTrp: 0.636 ± 0.023	3.049IleTyr: 3.049 ± 0.051	0.0IleXaa: 0.0 ± 0.0
Lys	5.115LysAla: 5.115 ± 0.072	0.312LysCys: 0.312 ± 0.018	4.903LysAsp: 4.903 ± 0.095	7.276LysGlu: 7.276 ± 0.091	2.663LysPhe: 2.663 ± 0.052	5.062LysGly: 5.062 ± 0.087	1.349LysHis: 1.349 ± 0.038	5.496LysIle: 5.496 ± 0.075	6.481LysLys: 6.481 ± 0.096	6.448LysLeu: 6.448 ± 0.077	2.126LysMet: 2.126 ± 0.045	4.633LysAsn: 4.633 ± 0.065	2.262LysPro: 2.262 ± 0.042	3.12LysGln: 3.12 ± 0.058	2.715LysArg: 2.715 ± 0.049	4.37LysSer: 4.37 ± 0.066	4.447LysThr: 4.447 ± 0.072	5.462LysVal: 5.462 ± 0.082	0.776LysTrp: 0.776 ± 0.029	3.373LysTyr: 3.373 ± 0.058	0.0LysXaa: 0.0 ± 0.0
Leu	6.003LeuAla: 6.003 ± 0.075	0.744LeuCys: 0.744 ± 0.028	5.344LeuAsp: 5.344 ± 0.08	6.305LeuGlu: 6.305 ± 0.096	4.953LeuPhe: 4.953 ± 0.081	5.981LeuGly: 5.981 ± 0.082	1.597LeuHis: 1.597 ± 0.04	6.813LeuIle: 6.813 ± 0.112	7.404LeuLys: 7.404 ± 0.09	9.312LeuLeu: 9.312 ± 0.11	2.289LeuMet: 2.289 ± 0.052	5.243LeuAsn: 5.243 ± 0.08	3.546LeuPro: 3.546 ± 0.065	3.154LeuGln: 3.154 ± 0.066	3.142LeuArg: 3.142 ± 0.055	6.848LeuSer: 6.848 ± 0.084	5.386LeuThr: 5.386 ± 0.068	5.993LeuVal: 5.993 ± 0.089	0.803LeuTrp: 0.803 ± 0.027	3.626LeuTyr: 3.626 ± 0.052	0.0LeuXaa: 0.0 ± 0.0
Met	1.57MetAla: 1.57 ± 0.042	0.171MetCys: 0.171 ± 0.013	1.144MetAsp: 1.144 ± 0.032	1.302MetGlu: 1.302 ± 0.035	1.027MetPhe: 1.027 ± 0.031	1.436MetGly: 1.436 ± 0.037	0.411MetHis: 0.411 ± 0.019	1.699MetIle: 1.699 ± 0.045	2.171MetLys: 2.171 ± 0.042	2.176MetLeu: 2.176 ± 0.045	0.702MetMet: 0.702 ± 0.028	1.382MetAsn: 1.382 ± 0.03	0.873MetPro: 0.873 ± 0.028	0.822MetGln: 0.822 ± 0.026	0.958MetArg: 0.958 ± 0.028	1.639MetSer: 1.639 ± 0.039	1.387MetThr: 1.387 ± 0.037	1.348MetVal: 1.348 ± 0.038	0.201MetTrp: 0.201 ± 0.013	0.965MetTyr: 0.965 ± 0.032	0.0MetXaa: 0.0 ± 0.0
Asn	3.531AsnAla: 3.531 ± 0.063	0.357AsnCys: 0.357 ± 0.018	2.882AsnAsp: 2.882 ± 0.048	3.562AsnGlu: 3.562 ± 0.058	2.571AsnPhe: 2.571 ± 0.048	3.376AsnGly: 3.376 ± 0.081	1.027AsnHis: 1.027 ± 0.027	4.743AsnIle: 4.743 ± 0.072	4.896AsnLys: 4.896 ± 0.075	5.033AsnLeu: 5.033 ± 0.064	1.226AsnMet: 1.226 ± 0.031	3.767AsnAsn: 3.767 ± 0.079	2.324AsnPro: 2.324 ± 0.05	2.247AsnGln: 2.247 ± 0.049	2.103AsnArg: 2.103 ± 0.048	3.501AsnSer: 3.501 ± 0.061	3.654AsnThr: 3.654 ± 0.063	3.544AsnVal: 3.544 ± 0.059	0.645AsnTrp: 0.645 ± 0.027	2.84AsnTyr: 2.84 ± 0.063	0.0AsnXaa: 0.0 ± 0.0
Pro	1.759ProAla: 1.759 ± 0.046	0.198ProCys: 0.198 ± 0.014	1.599ProAsp: 1.599 ± 0.042	2.343ProGlu: 2.343 ± 0.042	1.762ProPhe: 1.762 ± 0.04	1.689ProGly: 1.689 ± 0.046	0.577ProHis: 0.577 ± 0.022	2.844ProIle: 2.844 ± 0.057	2.28ProLys: 2.28 ± 0.044	2.885ProLeu: 2.885 ± 0.054	0.766ProMet: 0.766 ± 0.027	1.941ProAsn: 1.941 ± 0.045	0.655ProPro: 0.655 ± 0.029	1.035ProGln: 1.035 ± 0.032	0.863ProArg: 0.863 ± 0.031	2.109ProSer: 2.109 ± 0.049	2.044ProThr: 2.044 ± 0.045	2.186ProVal: 2.186 ± 0.042	0.27ProTrp: 0.27 ± 0.015	1.44ProTyr: 1.44 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	2.218GlnAla: 2.218 ± 0.05	0.198GlnCys: 0.198 ± 0.013	1.815GlnAsp: 1.815 ± 0.042	2.694GlnGlu: 2.694 ± 0.05	1.557GlnPhe: 1.557 ± 0.038	2.137GlnGly: 2.137 ± 0.049	0.66GlnHis: 0.66 ± 0.023	2.621GlnIle: 2.621 ± 0.052	2.819GlnLys: 2.819 ± 0.045	3.606GlnLeu: 3.606 ± 0.061	0.873GlnMet: 0.873 ± 0.026	1.946GlnAsn: 1.946 ± 0.049	0.931GlnPro: 0.931 ± 0.028	1.585GlnGln: 1.585 ± 0.047	1.246GlnArg: 1.246 ± 0.039	2.101GlnSer: 2.101 ± 0.047	1.817GlnThr: 1.817 ± 0.041	2.363GlnVal: 2.363 ± 0.04	0.433GlnTrp: 0.433 ± 0.021	1.804GlnTyr: 1.804 ± 0.05	0.0GlnXaa: 0.0 ± 0.0
Arg	2.025ArgAla: 2.025 ± 0.041	0.194ArgCys: 0.194 ± 0.011	1.827ArgAsp: 1.827 ± 0.046	2.477ArgGlu: 2.477 ± 0.05	1.727ArgPhe: 1.727 ± 0.041	1.935ArgGly: 1.935 ± 0.05	0.573ArgHis: 0.573 ± 0.022	2.955ArgIle: 2.955 ± 0.061	2.52ArgLys: 2.52 ± 0.059	3.345ArgLeu: 3.345 ± 0.059	0.963ArgMet: 0.963 ± 0.036	1.836ArgAsn: 1.836 ± 0.041	1.015ArgPro: 1.015 ± 0.031	1.16ArgGln: 1.16 ± 0.036	1.246ArgArg: 1.246 ± 0.039	1.868ArgSer: 1.868 ± 0.044	1.76ArgThr: 1.76 ± 0.04	2.397ArgVal: 2.397 ± 0.046	0.386ArgTrp: 0.386 ± 0.02	1.698ArgTyr: 1.698 ± 0.04	0.0ArgXaa: 0.0 ± 0.0
Ser	3.47SerAla: 3.47 ± 0.058	0.601SerCys: 0.601 ± 0.027	3.313SerAsp: 3.313 ± 0.053	3.594SerGlu: 3.594 ± 0.058	3.878SerPhe: 3.878 ± 0.071	3.951SerGly: 3.951 ± 0.067	1.059SerHis: 1.059 ± 0.03	5.55SerIle: 5.55 ± 0.082	4.907SerLys: 4.907 ± 0.07	6.303SerLeu: 6.303 ± 0.083	1.384SerMet: 1.384 ± 0.033	3.66SerAsn: 3.66 ± 0.064	1.929SerPro: 1.929 ± 0.043	1.981SerGln: 1.981 ± 0.044	2.055SerArg: 2.055 ± 0.043	4.313SerSer: 4.313 ± 0.085	3.74SerThr: 3.74 ± 0.061	4.116SerVal: 4.116 ± 0.068	0.625SerTrp: 0.625 ± 0.025	3.002SerTyr: 3.002 ± 0.069	0.0SerXaa: 0.0 ± 0.0
Thr	3.73ThrAla: 3.73 ± 0.072	0.338ThrCys: 0.338 ± 0.016	3.253ThrAsp: 3.253 ± 0.059	3.496ThrGlu: 3.496 ± 0.065	2.716ThrPhe: 2.716 ± 0.049	3.528ThrGly: 3.528 ± 0.062	1.058ThrHis: 1.058 ± 0.036	4.869ThrIle: 4.869 ± 0.07	4.139ThrLys: 4.139 ± 0.062	5.613ThrLeu: 5.613 ± 0.078	1.166ThrMet: 1.166 ± 0.032	3.292ThrAsn: 3.292 ± 0.072	2.434ThrPro: 2.434 ± 0.046	1.934ThrGln: 1.934 ± 0.046	1.654ThrArg: 1.654 ± 0.04	3.744ThrSer: 3.744 ± 0.06	3.723ThrThr: 3.723 ± 0.07	4.137ThrVal: 4.137 ± 0.083	0.535ThrTrp: 0.535 ± 0.025	2.626ThrTyr: 2.626 ± 0.066	0.0ThrXaa: 0.0 ± 0.0
Val	4.193ValAla: 4.193 ± 0.065	0.545ValCys: 0.545 ± 0.022	3.956ValAsp: 3.956 ± 0.06	4.659ValGlu: 4.659 ± 0.072	3.489ValPhe: 3.489 ± 0.062	4.194ValGly: 4.194 ± 0.066	0.993ValHis: 0.993 ± 0.029	5.318ValIle: 5.318 ± 0.073	4.918ValLys: 4.918 ± 0.081	6.757ValLeu: 6.757 ± 0.081	1.484ValMet: 1.484 ± 0.04	3.683ValAsn: 3.683 ± 0.06	2.144ValPro: 2.144 ± 0.051	2.05ValGln: 2.05 ± 0.044	2.16ValArg: 2.16 ± 0.047	4.558ValSer: 4.558 ± 0.067	3.722ValThr: 3.722 ± 0.088	4.794ValVal: 4.794 ± 0.079	0.588ValTrp: 0.588 ± 0.023	2.813ValTyr: 2.813 ± 0.052	0.0ValXaa: 0.0 ± 0.0
Trp	0.56TrpAla: 0.56 ± 0.023	0.097TrpCys: 0.097 ± 0.01	0.601TrpAsp: 0.601 ± 0.024	0.613TrpGlu: 0.613 ± 0.024	0.499TrpPhe: 0.499 ± 0.022	0.645TrpGly: 0.645 ± 0.029	0.183TrpHis: 0.183 ± 0.012	0.726TrpIle: 0.726 ± 0.026	0.713TrpLys: 0.713 ± 0.024	0.943TrpLeu: 0.943 ± 0.028	0.286TrpMet: 0.286 ± 0.016	0.616TrpAsn: 0.616 ± 0.023	0.187TrpPro: 0.187 ± 0.014	0.411TrpGln: 0.411 ± 0.021	0.351TrpArg: 0.351 ± 0.018	0.604TrpSer: 0.604 ± 0.025	0.554TrpThr: 0.554 ± 0.019	0.628TrpVal: 0.628 ± 0.028	0.118TrpTrp: 0.118 ± 0.01	0.418TrpTyr: 0.418 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.655TyrAla: 2.655 ± 0.052	0.369TyrCys: 0.369 ± 0.02	2.649TyrAsp: 2.649 ± 0.059	2.591TyrGlu: 2.591 ± 0.049	2.533TyrPhe: 2.533 ± 0.054	2.726TyrGly: 2.726 ± 0.061	0.891TyrHis: 0.891 ± 0.029	3.295TyrIle: 3.295 ± 0.061	3.493TyrLys: 3.493 ± 0.066	4.298TyrLeu: 4.298 ± 0.078	0.891TyrMet: 0.891 ± 0.029	2.96TyrAsn: 2.96 ± 0.063	1.511TyrPro: 1.511 ± 0.038	1.715TyrGln: 1.715 ± 0.038	1.712TyrArg: 1.712 ± 0.042	3.038TyrSer: 3.038 ± 0.066	2.793TyrThr: 2.793 ± 0.061	2.518TyrVal: 2.518 ± 0.045	0.471TyrTrp: 0.471 ± 0.019	2.415TyrTyr: 2.415 ± 0.063	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3534 proteins (1144917 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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