Amino acid dipepetide frequency for Psittacine adenovirus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.908AlaAla: 9.908 ± 2.12
1.445AlaCys: 1.445 ± 0.432
4.541AlaAsp: 4.541 ± 0.619
4.335AlaGlu: 4.335 ± 0.812
3.303AlaPhe: 3.303 ± 0.487
3.922AlaGly: 3.922 ± 0.709
1.239AlaHis: 1.239 ± 0.284
3.406AlaIle: 3.406 ± 0.736
2.58AlaLys: 2.58 ± 0.707
9.082AlaLeu: 9.082 ± 0.974
1.651AlaMet: 1.651 ± 0.54
2.89AlaAsn: 2.89 ± 0.66
5.677AlaPro: 5.677 ± 0.933
2.58AlaGln: 2.58 ± 0.552
4.541AlaArg: 4.541 ± 0.522
5.78AlaSer: 5.78 ± 0.814
3.2AlaThr: 3.2 ± 0.869
7.947AlaVal: 7.947 ± 0.863
0.619AlaTrp: 0.619 ± 0.219
2.064AlaTyr: 2.064 ± 0.589
0.0AlaXaa: 0.0 ± 0.0
Cys
1.342CysAla: 1.342 ± 0.445
1.342CysCys: 1.342 ± 0.504
1.032CysAsp: 1.032 ± 0.395
1.651CysGlu: 1.651 ± 0.581
1.239CysPhe: 1.239 ± 0.433
1.961CysGly: 1.961 ± 0.511
0.413CysHis: 0.413 ± 0.211
0.929CysIle: 0.929 ± 0.337
0.929CysLys: 0.929 ± 0.304
1.755CysLeu: 1.755 ± 0.533
0.413CysMet: 0.413 ± 0.214
1.548CysAsn: 1.548 ± 0.405
1.548CysPro: 1.548 ± 0.25
0.619CysGln: 0.619 ± 0.212
2.374CysArg: 2.374 ± 0.537
2.477CysSer: 2.477 ± 0.767
1.548CysThr: 1.548 ± 0.455
1.445CysVal: 1.445 ± 0.385
0.413CysTrp: 0.413 ± 0.182
1.342CysTyr: 1.342 ± 0.353
0.0CysXaa: 0.0 ± 0.0
Asp
2.993AspAla: 2.993 ± 0.644
1.135AspCys: 1.135 ± 0.374
2.477AspAsp: 2.477 ± 0.705
3.406AspGlu: 3.406 ± 0.708
1.858AspPhe: 1.858 ± 0.42
3.922AspGly: 3.922 ± 0.66
1.239AspHis: 1.239 ± 0.398
2.89AspIle: 2.89 ± 0.62
0.929AspLys: 0.929 ± 0.264
4.438AspLeu: 4.438 ± 0.605
1.239AspMet: 1.239 ± 0.39
1.548AspAsn: 1.548 ± 0.466
2.58AspPro: 2.58 ± 0.535
1.342AspGln: 1.342 ± 0.403
4.335AspArg: 4.335 ± 0.724
4.128AspSer: 4.128 ± 0.603
3.819AspThr: 3.819 ± 0.631
2.683AspVal: 2.683 ± 0.436
0.516AspTrp: 0.516 ± 0.307
1.858AspTyr: 1.858 ± 0.377
0.0AspXaa: 0.0 ± 0.0
Glu
4.541GluAla: 4.541 ± 0.873
1.548GluCys: 1.548 ± 0.471
4.128GluAsp: 4.128 ± 0.789
5.367GluGlu: 5.367 ± 1.263
0.929GluPhe: 0.929 ± 0.281
3.922GluGly: 3.922 ± 0.663
0.413GluHis: 0.413 ± 0.161
1.961GluIle: 1.961 ± 0.472
1.651GluLys: 1.651 ± 0.453
4.748GluLeu: 4.748 ± 0.834
0.929GluMet: 0.929 ± 0.275
3.096GluAsn: 3.096 ± 0.57
3.922GluPro: 3.922 ± 0.645
1.858GluGln: 1.858 ± 0.369
4.541GluArg: 4.541 ± 0.804
2.787GluSer: 2.787 ± 0.494
3.716GluThr: 3.716 ± 0.682
2.374GluVal: 2.374 ± 0.369
0.929GluTrp: 0.929 ± 0.281
1.135GluTyr: 1.135 ± 0.329
0.0GluXaa: 0.0 ± 0.0
Phe
2.58PheAla: 2.58 ± 0.363
1.548PheCys: 1.548 ± 0.432
1.961PheAsp: 1.961 ± 0.399
1.445PheGlu: 1.445 ± 0.347
1.961PhePhe: 1.961 ± 0.349
1.445PheGly: 1.445 ± 0.34
1.032PheHis: 1.032 ± 0.238
2.167PheIle: 2.167 ± 0.381
1.032PheLys: 1.032 ± 0.262
3.2PheLeu: 3.2 ± 0.495
1.445PheMet: 1.445 ± 0.277
1.135PheAsn: 1.135 ± 0.28
3.2PhePro: 3.2 ± 0.721
1.445PheGln: 1.445 ± 0.364
3.096PheArg: 3.096 ± 0.473
3.922PheSer: 3.922 ± 0.577
2.683PheThr: 2.683 ± 0.618
2.167PheVal: 2.167 ± 0.375
0.619PheTrp: 0.619 ± 0.255
1.548PheTyr: 1.548 ± 0.327
0.0PheXaa: 0.0 ± 0.0
Gly
5.986GlyAla: 5.986 ± 0.716
0.929GlyCys: 0.929 ± 0.317
2.89GlyAsp: 2.89 ± 0.513
4.335GlyGlu: 4.335 ± 0.783
1.651GlyPhe: 1.651 ± 0.298
5.677GlyGly: 5.677 ± 1.005
0.826GlyHis: 0.826 ± 0.283
2.064GlyIle: 2.064 ± 0.373
2.993GlyLys: 2.993 ± 0.541
5.47GlyLeu: 5.47 ± 1.097
1.135GlyMet: 1.135 ± 0.315
3.096GlyAsn: 3.096 ± 0.614
2.064GlyPro: 2.064 ± 0.48
2.58GlyGln: 2.58 ± 0.55
4.851GlyArg: 4.851 ± 0.76
5.47GlySer: 5.47 ± 0.836
4.025GlyThr: 4.025 ± 0.784
4.851GlyVal: 4.851 ± 0.878
1.032GlyTrp: 1.032 ± 0.255
1.548GlyTyr: 1.548 ± 0.339
0.0GlyXaa: 0.0 ± 0.0
His
1.032HisAla: 1.032 ± 0.382
1.342HisCys: 1.342 ± 0.522
0.826HisAsp: 0.826 ± 0.264
0.31HisGlu: 0.31 ± 0.179
1.135HisPhe: 1.135 ± 0.352
1.858HisGly: 1.858 ± 0.479
0.516HisHis: 0.516 ± 0.236
0.826HisIle: 0.826 ± 0.3
0.929HisLys: 0.929 ± 0.284
2.064HisLeu: 2.064 ± 0.387
0.206HisMet: 0.206 ± 0.122
0.929HisAsn: 0.929 ± 0.294
0.722HisPro: 0.722 ± 0.229
0.413HisGln: 0.413 ± 0.225
1.032HisArg: 1.032 ± 0.254
1.961HisSer: 1.961 ± 0.415
1.032HisThr: 1.032 ± 0.363
1.239HisVal: 1.239 ± 0.439
0.413HisTrp: 0.413 ± 0.244
1.135HisTyr: 1.135 ± 0.296
0.0HisXaa: 0.0 ± 0.0
Ile
3.2IleAla: 3.2 ± 0.579
1.342IleCys: 1.342 ± 0.341
2.58IleAsp: 2.58 ± 0.483
1.239IleGlu: 1.239 ± 0.289
1.342IlePhe: 1.342 ± 0.497
2.58IleGly: 2.58 ± 0.523
0.31IleHis: 0.31 ± 0.147
2.064IleIle: 2.064 ± 0.529
2.167IleLys: 2.167 ± 0.489
2.374IleLeu: 2.374 ± 0.459
0.826IleMet: 0.826 ± 0.224
1.342IleAsn: 1.342 ± 0.407
2.167IlePro: 2.167 ± 0.414
1.755IleGln: 1.755 ± 0.454
3.096IleArg: 3.096 ± 0.613
4.335IleSer: 4.335 ± 0.593
3.096IleThr: 3.096 ± 0.522
3.2IleVal: 3.2 ± 0.572
0.31IleTrp: 0.31 ± 0.211
1.445IleTyr: 1.445 ± 0.346
0.0IleXaa: 0.0 ± 0.0
Lys
3.509LysAla: 3.509 ± 0.824
0.722LysCys: 0.722 ± 0.261
1.548LysAsp: 1.548 ± 0.329
2.683LysGlu: 2.683 ± 0.688
1.548LysPhe: 1.548 ± 0.386
1.548LysGly: 1.548 ± 0.417
1.135LysHis: 1.135 ± 0.314
1.755LysIle: 1.755 ± 0.423
1.239LysLys: 1.239 ± 0.322
4.335LysLeu: 4.335 ± 0.748
0.31LysMet: 0.31 ± 0.201
1.961LysAsn: 1.961 ± 0.428
1.961LysPro: 1.961 ± 0.411
1.342LysGln: 1.342 ± 0.41
2.374LysArg: 2.374 ± 0.408
1.961LysSer: 1.961 ± 0.457
2.477LysThr: 2.477 ± 0.583
2.167LysVal: 2.167 ± 0.4
0.413LysTrp: 0.413 ± 0.233
1.342LysTyr: 1.342 ± 0.305
0.0LysXaa: 0.0 ± 0.0
Leu
6.193LeuAla: 6.193 ± 1.109
2.064LeuCys: 2.064 ± 0.587
4.644LeuAsp: 4.644 ± 0.572
5.16LeuGlu: 5.16 ± 0.63
3.096LeuPhe: 3.096 ± 0.394
5.573LeuGly: 5.573 ± 0.791
2.993LeuHis: 2.993 ± 0.502
3.406LeuIle: 3.406 ± 0.651
3.406LeuLys: 3.406 ± 0.478
9.082LeuLeu: 9.082 ± 1.033
2.89LeuMet: 2.89 ± 0.436
4.025LeuAsn: 4.025 ± 0.591
6.812LeuPro: 6.812 ± 0.614
6.089LeuGln: 6.089 ± 1.104
5.573LeuArg: 5.573 ± 0.793
8.463LeuSer: 8.463 ± 0.769
6.399LeuThr: 6.399 ± 0.906
4.954LeuVal: 4.954 ± 0.625
1.651LeuTrp: 1.651 ± 0.352
3.096LeuTyr: 3.096 ± 0.583
0.0LeuXaa: 0.0 ± 0.0
Met
2.477MetAla: 2.477 ± 0.415
0.413MetCys: 0.413 ± 0.215
0.722MetAsp: 0.722 ± 0.208
1.342MetGlu: 1.342 ± 0.413
1.032MetPhe: 1.032 ± 0.299
1.135MetGly: 1.135 ± 0.297
0.722MetHis: 0.722 ± 0.209
0.826MetIle: 0.826 ± 0.248
0.929MetLys: 0.929 ± 0.354
1.755MetLeu: 1.755 ± 0.383
0.413MetMet: 0.413 ± 0.182
1.239MetAsn: 1.239 ± 0.392
1.032MetPro: 1.032 ± 0.285
0.31MetGln: 0.31 ± 0.172
1.651MetArg: 1.651 ± 0.444
1.548MetSer: 1.548 ± 0.402
1.135MetThr: 1.135 ± 0.286
1.858MetVal: 1.858 ± 0.332
0.31MetTrp: 0.31 ± 0.159
0.826MetTyr: 0.826 ± 0.295
0.0MetXaa: 0.0 ± 0.0
Asn
4.128AsnAla: 4.128 ± 0.767
1.135AsnCys: 1.135 ± 0.293
2.477AsnAsp: 2.477 ± 0.754
1.342AsnGlu: 1.342 ± 0.231
2.167AsnPhe: 2.167 ± 0.461
2.683AsnGly: 2.683 ± 0.545
0.516AsnHis: 0.516 ± 0.23
2.271AsnIle: 2.271 ± 0.388
1.239AsnLys: 1.239 ± 0.31
3.612AsnLeu: 3.612 ± 0.642
0.826AsnMet: 0.826 ± 0.34
1.858AsnAsn: 1.858 ± 0.586
2.89AsnPro: 2.89 ± 0.407
1.755AsnGln: 1.755 ± 0.389
2.064AsnArg: 2.064 ± 0.413
2.89AsnSer: 2.89 ± 0.62
3.096AsnThr: 3.096 ± 0.656
2.993AsnVal: 2.993 ± 0.589
0.516AsnTrp: 0.516 ± 0.226
1.961AsnTyr: 1.961 ± 0.654
0.0AsnXaa: 0.0 ± 0.0
Pro
4.438ProAla: 4.438 ± 0.806
1.342ProCys: 1.342 ± 0.374
3.819ProAsp: 3.819 ± 0.808
4.438ProGlu: 4.438 ± 0.643
3.096ProPhe: 3.096 ± 0.363
2.477ProGly: 2.477 ± 0.494
1.858ProHis: 1.858 ± 0.526
2.271ProIle: 2.271 ± 0.353
3.096ProLys: 3.096 ± 0.575
7.018ProLeu: 7.018 ± 1.042
1.239ProMet: 1.239 ± 0.302
2.167ProAsn: 2.167 ± 0.602
6.089ProPro: 6.089 ± 1.142
2.064ProGln: 2.064 ± 0.511
3.716ProArg: 3.716 ± 0.526
5.78ProSer: 5.78 ± 0.609
2.683ProThr: 2.683 ± 0.376
4.748ProVal: 4.748 ± 1.034
0.619ProTrp: 0.619 ± 0.249
1.961ProTyr: 1.961 ± 0.609
0.0ProXaa: 0.0 ± 0.0
Gln
4.128GlnAla: 4.128 ± 0.665
1.032GlnCys: 1.032 ± 0.368
1.032GlnAsp: 1.032 ± 0.381
1.858GlnGlu: 1.858 ± 0.365
0.826GlnPhe: 0.826 ± 0.262
1.548GlnGly: 1.548 ± 0.399
1.032GlnHis: 1.032 ± 0.321
1.342GlnIle: 1.342 ± 0.271
1.961GlnLys: 1.961 ± 0.476
4.541GlnLeu: 4.541 ± 0.73
1.239GlnMet: 1.239 ± 0.385
1.755GlnAsn: 1.755 ± 0.483
2.374GlnPro: 2.374 ± 0.49
1.651GlnGln: 1.651 ± 0.349
2.477GlnArg: 2.477 ± 0.479
2.89GlnSer: 2.89 ± 0.513
2.993GlnThr: 2.993 ± 0.527
2.58GlnVal: 2.58 ± 0.63
0.413GlnTrp: 0.413 ± 0.205
0.826GlnTyr: 0.826 ± 0.292
0.0GlnXaa: 0.0 ± 0.0
Arg
5.367ArgAla: 5.367 ± 0.895
2.271ArgCys: 2.271 ± 0.632
3.406ArgAsp: 3.406 ± 0.642
3.406ArgGlu: 3.406 ± 0.643
1.961ArgPhe: 1.961 ± 0.429
4.232ArgGly: 4.232 ± 0.573
1.032ArgHis: 1.032 ± 0.348
2.58ArgIle: 2.58 ± 0.5
3.096ArgLys: 3.096 ± 0.533
7.018ArgLeu: 7.018 ± 0.768
1.445ArgMet: 1.445 ± 0.423
2.167ArgAsn: 2.167 ± 0.494
4.438ArgPro: 4.438 ± 0.658
3.303ArgGln: 3.303 ± 0.796
9.599ArgArg: 9.599 ± 2.636
4.541ArgSer: 4.541 ± 0.569
3.509ArgThr: 3.509 ± 0.825
3.819ArgVal: 3.819 ± 0.679
1.135ArgTrp: 1.135 ± 0.276
2.477ArgTyr: 2.477 ± 0.483
0.0ArgXaa: 0.0 ± 0.0
Ser
6.399SerAla: 6.399 ± 0.649
1.651SerCys: 1.651 ± 0.434
3.819SerAsp: 3.819 ± 0.655
3.303SerGlu: 3.303 ± 0.694
3.612SerPhe: 3.612 ± 0.446
6.709SerGly: 6.709 ± 1.19
1.135SerHis: 1.135 ± 0.312
2.787SerIle: 2.787 ± 0.377
1.651SerLys: 1.651 ± 0.36
7.844SerLeu: 7.844 ± 0.799
1.135SerMet: 1.135 ± 0.314
3.612SerAsn: 3.612 ± 0.5
5.883SerPro: 5.883 ± 0.768
2.683SerGln: 2.683 ± 0.48
4.748SerArg: 4.748 ± 0.855
7.328SerSer: 7.328 ± 1.356
3.612SerThr: 3.612 ± 0.612
5.573SerVal: 5.573 ± 0.749
1.445SerTrp: 1.445 ± 0.318
3.406SerTyr: 3.406 ± 0.65
0.0SerXaa: 0.0 ± 0.0
Thr
6.089ThrAla: 6.089 ± 0.867
1.342ThrCys: 1.342 ± 0.423
2.477ThrAsp: 2.477 ± 0.436
3.716ThrGlu: 3.716 ± 0.534
1.961ThrPhe: 1.961 ± 0.432
4.954ThrGly: 4.954 ± 0.723
1.342ThrHis: 1.342 ± 0.298
2.064ThrIle: 2.064 ± 0.418
1.755ThrLys: 1.755 ± 0.386
6.089ThrLeu: 6.089 ± 0.979
1.239ThrMet: 1.239 ± 0.341
2.477ThrAsn: 2.477 ± 0.439
4.025ThrPro: 4.025 ± 0.604
2.064ThrGln: 2.064 ± 0.403
3.819ThrArg: 3.819 ± 0.626
3.303ThrSer: 3.303 ± 0.521
3.922ThrThr: 3.922 ± 0.612
4.438ThrVal: 4.438 ± 0.558
1.032ThrTrp: 1.032 ± 0.297
3.2ThrTyr: 3.2 ± 0.721
0.0ThrXaa: 0.0 ± 0.0
Val
4.335ValAla: 4.335 ± 0.655
2.271ValCys: 2.271 ± 0.508
2.374ValAsp: 2.374 ± 0.549
2.58ValGlu: 2.58 ± 0.59
3.096ValPhe: 3.096 ± 0.618
3.819ValGly: 3.819 ± 0.575
1.135ValHis: 1.135 ± 0.29
3.509ValIle: 3.509 ± 0.566
2.58ValLys: 2.58 ± 0.453
6.915ValLeu: 6.915 ± 0.798
1.755ValMet: 1.755 ± 0.381
2.167ValAsn: 2.167 ± 0.774
4.748ValPro: 4.748 ± 0.767
2.477ValGln: 2.477 ± 0.418
4.232ValArg: 4.232 ± 0.653
5.057ValSer: 5.057 ± 0.906
5.367ValThr: 5.367 ± 0.829
3.819ValVal: 3.819 ± 0.562
0.413ValTrp: 0.413 ± 0.175
3.2ValTyr: 3.2 ± 0.715
0.0ValXaa: 0.0 ± 0.0
Trp
0.516TrpAla: 0.516 ± 0.205
0.206TrpCys: 0.206 ± 0.208
0.722TrpAsp: 0.722 ± 0.193
0.722TrpGlu: 0.722 ± 0.221
0.826TrpPhe: 0.826 ± 0.247
0.619TrpGly: 0.619 ± 0.29
0.31TrpHis: 0.31 ± 0.194
0.722TrpIle: 0.722 ± 0.222
1.032TrpLys: 1.032 ± 0.349
0.722TrpLeu: 0.722 ± 0.252
0.31TrpMet: 0.31 ± 0.163
0.826TrpAsn: 0.826 ± 0.252
0.722TrpPro: 0.722 ± 0.271
0.929TrpGln: 0.929 ± 0.264
0.929TrpArg: 0.929 ± 0.312
1.342TrpSer: 1.342 ± 0.311
1.135TrpThr: 1.135 ± 0.397
0.619TrpVal: 0.619 ± 0.261
0.206TrpTrp: 0.206 ± 0.158
0.103TrpTyr: 0.103 ± 0.095
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.548TyrAla: 1.548 ± 0.402
1.239TyrCys: 1.239 ± 0.339
1.858TyrAsp: 1.858 ± 0.578
1.961TyrGlu: 1.961 ± 0.448
2.993TyrPhe: 2.993 ± 0.549
2.89TyrGly: 2.89 ± 0.497
0.722TyrHis: 0.722 ± 0.248
0.929TyrIle: 0.929 ± 0.225
1.135TyrLys: 1.135 ± 0.385
3.509TyrLeu: 3.509 ± 0.667
0.929TyrMet: 0.929 ± 0.252
2.58TyrAsn: 2.58 ± 0.484
2.064TyrPro: 2.064 ± 0.398
1.239TyrGln: 1.239 ± 0.433
1.755TyrArg: 1.755 ± 0.351
2.374TyrSer: 2.374 ± 0.672
1.858TyrThr: 1.858 ± 0.472
2.374TyrVal: 2.374 ± 0.555
0.516TyrTrp: 0.516 ± 0.241
1.651TyrTyr: 1.651 ± 0.48
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 29 proteins (9690 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski