Amino acid dipepetide frequency for Circovirus-like genome DCCV-10

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.696AlaAla: 8.696 ± 3.199
0.0AlaCys: 0.0 ± 0.0
4.969AlaAsp: 4.969 ± 1.33
1.242AlaGlu: 1.242 ± 0.867
1.242AlaPhe: 1.242 ± 0.867
2.484AlaGly: 2.484 ± 0.665
1.242AlaHis: 1.242 ± 0.955
2.484AlaIle: 2.484 ± 0.665
3.727AlaLys: 3.727 ± 1.215
11.18AlaLeu: 11.18 ± 2.993
4.969AlaMet: 4.969 ± 1.33
2.484AlaAsn: 2.484 ± 0.665
4.969AlaPro: 4.969 ± 1.831
6.211AlaGln: 6.211 ± 2.398
4.969AlaArg: 4.969 ± 3.265
6.211AlaSer: 6.211 ± 3.056
2.484AlaThr: 2.484 ± 1.735
3.727AlaVal: 3.727 ± 2.602
1.242AlaTrp: 1.242 ± 0.955
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.242CysAsp: 1.242 ± 0.867
1.242CysGlu: 1.242 ± 0.955
1.242CysPhe: 1.242 ± 0.955
1.242CysGly: 1.242 ± 0.955
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
1.242CysLeu: 1.242 ± 0.955
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
1.242CysGln: 1.242 ± 2.298
2.484CysArg: 2.484 ± 1.911
0.0CysSer: 0.0 ± 0.0
2.484CysThr: 2.484 ± 2.291
2.484CysVal: 2.484 ± 2.291
1.242CysTrp: 1.242 ± 0.867
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.484AspAla: 2.484 ± 1.735
0.0AspCys: 0.0 ± 0.0
6.211AspAsp: 6.211 ± 1.757
4.969AspGlu: 4.969 ± 2.302
2.484AspPhe: 2.484 ± 0.665
7.453AspGly: 7.453 ± 2.799
0.0AspHis: 0.0 ± 0.0
2.484AspIle: 2.484 ± 0.665
2.484AspLys: 2.484 ± 0.665
6.211AspLeu: 6.211 ± 2.839
1.242AspMet: 1.242 ± 0.955
2.484AspAsn: 2.484 ± 0.665
2.484AspPro: 2.484 ± 0.665
2.484AspGln: 2.484 ± 0.665
3.727AspArg: 3.727 ± 1.399
2.484AspSer: 2.484 ± 0.665
4.969AspThr: 4.969 ± 3.469
2.484AspVal: 2.484 ± 0.665
0.0AspTrp: 0.0 ± 0.0
2.484AspTyr: 2.484 ± 0.665
0.0AspXaa: 0.0 ± 0.0
Glu
0.0GluAla: 0.0 ± 0.0
1.242GluCys: 1.242 ± 0.955
0.0GluAsp: 0.0 ± 0.0
1.242GluGlu: 1.242 ± 0.955
1.242GluPhe: 1.242 ± 0.867
1.242GluGly: 1.242 ± 0.955
2.484GluHis: 2.484 ± 1.911
1.242GluIle: 1.242 ± 0.955
1.242GluLys: 1.242 ± 0.867
6.211GluLeu: 6.211 ± 3.235
0.0GluMet: 0.0 ± 0.845
1.242GluAsn: 1.242 ± 0.955
6.211GluPro: 6.211 ± 4.013
0.0GluGln: 0.0 ± 0.0
2.484GluArg: 2.484 ± 0.665
2.484GluSer: 2.484 ± 0.665
4.969GluThr: 4.969 ± 2.004
4.969GluVal: 4.969 ± 2.302
2.484GluTrp: 2.484 ± 1.911
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.0PheCys: 0.0 ± 0.0
7.453PheAsp: 7.453 ± 3.689
1.242PheGlu: 1.242 ± 0.955
1.242PhePhe: 1.242 ± 0.867
0.0PheGly: 0.0 ± 0.0
1.242PheHis: 1.242 ± 0.955
2.484PheIle: 2.484 ± 1.735
1.242PheLys: 1.242 ± 0.955
1.242PheLeu: 1.242 ± 0.867
0.0PheMet: 0.0 ± 0.0
1.242PheAsn: 1.242 ± 0.867
0.0PhePro: 0.0 ± 0.0
0.0PheGln: 0.0 ± 0.0
1.242PheArg: 1.242 ± 0.867
2.484PheSer: 2.484 ± 0.665
2.484PheThr: 2.484 ± 1.911
2.484PheVal: 2.484 ± 0.665
0.0PheTrp: 0.0 ± 0.0
2.484PheTyr: 2.484 ± 0.665
0.0PheXaa: 0.0 ± 0.0
Gly
8.696GlyAla: 8.696 ± 2.823
0.0GlyCys: 0.0 ± 0.0
1.242GlyAsp: 1.242 ± 0.867
3.727GlyGlu: 3.727 ± 2.866
1.242GlyPhe: 1.242 ± 0.955
3.727GlyGly: 3.727 ± 1.215
1.242GlyHis: 1.242 ± 0.955
0.0GlyIle: 0.0 ± 0.0
3.727GlyLys: 3.727 ± 1.399
0.0GlyLeu: 0.0 ± 0.0
0.0GlyMet: 0.0 ± 0.0
1.242GlyAsn: 1.242 ± 0.955
1.242GlyPro: 1.242 ± 0.867
2.484GlyGln: 2.484 ± 0.665
6.211GlyArg: 6.211 ± 1.539
6.211GlySer: 6.211 ± 3.913
6.211GlyThr: 6.211 ± 1.972
4.969GlyVal: 4.969 ± 2.004
0.0GlyTrp: 0.0 ± 0.0
3.727GlyTyr: 3.727 ± 1.399
0.0GlyXaa: 0.0 ± 0.0
His
1.242HisAla: 1.242 ± 0.955
1.242HisCys: 1.242 ± 2.298
2.484HisAsp: 2.484 ± 0.665
1.242HisGlu: 1.242 ± 0.955
1.242HisPhe: 1.242 ± 0.955
2.484HisGly: 2.484 ± 1.911
0.0HisHis: 0.0 ± 0.0
1.242HisIle: 1.242 ± 2.298
1.242HisLys: 1.242 ± 0.955
0.0HisLeu: 0.0 ± 0.0
0.0HisMet: 0.0 ± 0.0
1.242HisAsn: 1.242 ± 0.955
0.0HisPro: 0.0 ± 0.0
1.242HisGln: 1.242 ± 0.867
2.484HisArg: 2.484 ± 2.291
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
1.242HisVal: 1.242 ± 0.955
0.0HisTrp: 0.0 ± 0.0
1.242HisTyr: 1.242 ± 0.955
0.0HisXaa: 0.0 ± 0.0
Ile
7.453IleAla: 7.453 ± 3.157
0.0IleCys: 0.0 ± 0.0
0.0IleAsp: 0.0 ± 0.0
0.0IleGlu: 0.0 ± 0.0
0.0IlePhe: 0.0 ± 0.0
1.242IleGly: 1.242 ± 0.867
0.0IleHis: 0.0 ± 0.0
3.727IleIle: 3.727 ± 2.074
3.727IleLys: 3.727 ± 2.074
0.0IleLeu: 0.0 ± 0.0
2.484IleMet: 2.484 ± 2.01
0.0IleAsn: 0.0 ± 0.0
0.0IlePro: 0.0 ± 0.0
2.484IleGln: 2.484 ± 1.735
2.484IleArg: 2.484 ± 0.665
6.211IleSer: 6.211 ± 1.082
4.969IleThr: 4.969 ± 1.35
3.727IleVal: 3.727 ± 1.669
0.0IleTrp: 0.0 ± 0.0
2.484IleTyr: 2.484 ± 2.291
0.0IleXaa: 0.0 ± 0.0
Lys
6.211LysAla: 6.211 ± 1.082
0.0LysCys: 0.0 ± 0.0
0.0LysAsp: 0.0 ± 0.0
1.242LysGlu: 1.242 ± 0.867
2.484LysPhe: 2.484 ± 1.735
3.727LysGly: 3.727 ± 1.215
0.0LysHis: 0.0 ± 0.0
2.484LysIle: 2.484 ± 2.01
1.242LysLys: 1.242 ± 0.867
3.727LysLeu: 3.727 ± 2.602
0.0LysMet: 0.0 ± 0.0
1.242LysAsn: 1.242 ± 0.867
2.484LysPro: 2.484 ± 0.665
1.242LysGln: 1.242 ± 0.955
6.211LysArg: 6.211 ± 2.839
4.969LysSer: 4.969 ± 2.004
8.696LysThr: 8.696 ± 4.545
3.727LysVal: 3.727 ± 2.074
0.0LysTrp: 0.0 ± 0.0
1.242LysTyr: 1.242 ± 0.955
0.0LysXaa: 0.0 ± 0.0
Leu
2.484LeuAla: 2.484 ± 0.665
1.242LeuCys: 1.242 ± 0.955
2.484LeuAsp: 2.484 ± 0.665
7.453LeuGlu: 7.453 ± 2.799
1.242LeuPhe: 1.242 ± 0.955
2.484LeuGly: 2.484 ± 1.735
1.242LeuHis: 1.242 ± 0.955
1.242LeuIle: 1.242 ± 0.955
3.727LeuLys: 3.727 ± 2.602
3.727LeuLeu: 3.727 ± 1.399
1.242LeuMet: 1.242 ± 0.867
3.727LeuAsn: 3.727 ± 1.215
4.969LeuPro: 4.969 ± 1.35
2.484LeuGln: 2.484 ± 4.597
9.938LeuArg: 9.938 ± 4.604
3.727LeuSer: 3.727 ± 2.602
7.453LeuThr: 7.453 ± 2.101
9.938LeuVal: 9.938 ± 1.91
0.0LeuTrp: 0.0 ± 0.0
2.484LeuTyr: 2.484 ± 0.665
0.0LeuXaa: 0.0 ± 0.0
Met
1.242MetAla: 1.242 ± 0.867
0.0MetCys: 0.0 ± 0.0
2.484MetAsp: 2.484 ± 0.665
0.0MetGlu: 0.0 ± 0.0
2.484MetPhe: 2.484 ± 1.735
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
1.242MetIle: 1.242 ± 2.298
1.242MetLys: 1.242 ± 0.867
3.727MetLeu: 3.727 ± 1.669
0.0MetMet: 0.0 ± 0.0
1.242MetAsn: 1.242 ± 0.867
1.242MetPro: 1.242 ± 0.955
0.0MetGln: 0.0 ± 0.0
1.242MetArg: 1.242 ± 0.955
3.727MetSer: 3.727 ± 2.074
2.484MetThr: 2.484 ± 0.665
2.484MetVal: 2.484 ± 0.665
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.242AsnAla: 1.242 ± 0.867
3.727AsnCys: 3.727 ± 1.399
1.242AsnAsp: 1.242 ± 0.955
1.242AsnGlu: 1.242 ± 0.955
0.0AsnPhe: 0.0 ± 0.0
4.969AsnGly: 4.969 ± 2.004
2.484AsnHis: 2.484 ± 1.735
2.484AsnIle: 2.484 ± 0.665
1.242AsnLys: 1.242 ± 0.867
0.0AsnLeu: 0.0 ± 0.0
0.0AsnMet: 0.0 ± 0.0
1.242AsnAsn: 1.242 ± 0.955
2.484AsnPro: 2.484 ± 0.665
2.484AsnGln: 2.484 ± 1.735
3.727AsnArg: 3.727 ± 2.602
1.242AsnSer: 1.242 ± 0.867
3.727AsnThr: 3.727 ± 1.215
0.0AsnVal: 0.0 ± 0.0
1.242AsnTrp: 1.242 ± 2.298
3.727AsnTyr: 3.727 ± 1.399
0.0AsnXaa: 0.0 ± 0.0
Pro
3.727ProAla: 3.727 ± 2.866
0.0ProCys: 0.0 ± 0.0
2.484ProAsp: 2.484 ± 1.911
2.484ProGlu: 2.484 ± 1.911
2.484ProPhe: 2.484 ± 1.735
4.969ProGly: 4.969 ± 3.961
2.484ProHis: 2.484 ± 1.911
2.484ProIle: 2.484 ± 2.01
2.484ProLys: 2.484 ± 1.735
3.727ProLeu: 3.727 ± 2.602
0.0ProMet: 0.0 ± 0.0
2.484ProAsn: 2.484 ± 1.735
2.484ProPro: 2.484 ± 2.01
3.727ProGln: 3.727 ± 1.215
3.727ProArg: 3.727 ± 1.669
6.211ProSer: 6.211 ± 1.539
4.969ProThr: 4.969 ± 3.265
0.0ProVal: 0.0 ± 0.0
0.0ProTrp: 0.0 ± 0.0
1.242ProTyr: 1.242 ± 2.298
0.0ProXaa: 0.0 ± 0.0
Gln
1.242GlnAla: 1.242 ± 0.867
1.242GlnCys: 1.242 ± 0.955
1.242GlnAsp: 1.242 ± 0.867
2.484GlnGlu: 2.484 ± 2.291
0.0GlnPhe: 0.0 ± 0.0
2.484GlnGly: 2.484 ± 1.911
0.0GlnHis: 0.0 ± 0.0
1.242GlnIle: 1.242 ± 0.867
0.0GlnLys: 0.0 ± 0.0
7.453GlnLeu: 7.453 ± 1.996
0.0GlnMet: 0.0 ± 0.0
2.484GlnAsn: 2.484 ± 0.665
3.727GlnPro: 3.727 ± 1.215
2.484GlnGln: 2.484 ± 1.911
3.727GlnArg: 3.727 ± 4.23
2.484GlnSer: 2.484 ± 1.735
3.727GlnThr: 3.727 ± 2.074
6.211GlnVal: 6.211 ± 1.082
0.0GlnTrp: 0.0 ± 0.0
2.484GlnTyr: 2.484 ± 1.735
0.0GlnXaa: 0.0 ± 0.0
Arg
9.938ArgAla: 9.938 ± 4.604
2.484ArgCys: 2.484 ± 4.597
6.211ArgAsp: 6.211 ± 1.972
2.484ArgGlu: 2.484 ± 1.911
0.0ArgPhe: 0.0 ± 0.0
6.211ArgGly: 6.211 ± 3.569
0.0ArgHis: 0.0 ± 0.0
4.969ArgIle: 4.969 ± 2.302
1.242ArgLys: 1.242 ± 0.867
4.969ArgLeu: 4.969 ± 3.961
2.484ArgMet: 2.484 ± 0.665
2.484ArgAsn: 2.484 ± 1.735
6.211ArgPro: 6.211 ± 1.757
1.242ArgGln: 1.242 ± 2.298
4.969ArgArg: 4.969 ± 3.961
7.453ArgSer: 7.453 ± 3.337
7.453ArgThr: 7.453 ± 2.101
6.211ArgVal: 6.211 ± 1.972
2.484ArgTrp: 2.484 ± 0.665
4.969ArgTyr: 4.969 ± 3.821
0.0ArgXaa: 0.0 ± 0.0
Ser
4.969SerAla: 4.969 ± 1.35
1.242SerCys: 1.242 ± 0.867
3.727SerAsp: 3.727 ± 1.215
3.727SerGlu: 3.727 ± 1.399
3.727SerPhe: 3.727 ± 1.215
3.727SerGly: 3.727 ± 1.215
2.484SerHis: 2.484 ± 2.291
4.969SerIle: 4.969 ± 4.02
9.938SerLys: 9.938 ± 3.609
2.484SerLeu: 2.484 ± 2.01
2.484SerMet: 2.484 ± 1.412
3.727SerAsn: 3.727 ± 1.399
3.727SerPro: 3.727 ± 2.074
4.969SerGln: 4.969 ± 2.004
4.969SerArg: 4.969 ± 4.02
11.18SerSer: 11.18 ± 7.49
3.727SerThr: 3.727 ± 4.23
2.484SerVal: 2.484 ± 0.665
0.0SerTrp: 0.0 ± 0.0
2.484SerTyr: 2.484 ± 4.597
0.0SerXaa: 0.0 ± 0.0
Thr
9.938ThrAla: 9.938 ± 4.008
1.242ThrCys: 1.242 ± 0.955
6.211ThrAsp: 6.211 ± 2.839
2.484ThrGlu: 2.484 ± 1.735
0.0ThrPhe: 0.0 ± 0.0
3.727ThrGly: 3.727 ± 1.215
1.242ThrHis: 1.242 ± 0.955
2.484ThrIle: 2.484 ± 2.01
4.969ThrLys: 4.969 ± 1.35
4.969ThrLeu: 4.969 ± 1.33
1.242ThrMet: 1.242 ± 0.867
3.727ThrAsn: 3.727 ± 2.602
3.727ThrPro: 3.727 ± 1.399
3.727ThrGln: 3.727 ± 2.602
11.18ThrArg: 11.18 ± 4.158
4.969ThrSer: 4.969 ± 1.35
8.696ThrThr: 8.696 ± 0.665
8.696ThrVal: 8.696 ± 3.367
3.727ThrTrp: 3.727 ± 4.23
3.727ThrTyr: 3.727 ± 1.215
0.0ThrXaa: 0.0 ± 0.0
Val
1.242ValAla: 1.242 ± 0.867
0.0ValCys: 0.0 ± 0.0
4.969ValAsp: 4.969 ± 1.33
3.727ValGlu: 3.727 ± 1.399
4.969ValPhe: 4.969 ± 1.33
0.0ValGly: 0.0 ± 0.0
3.727ValHis: 3.727 ± 4.489
2.484ValIle: 2.484 ± 0.665
6.211ValLys: 6.211 ± 2.839
6.211ValLeu: 6.211 ± 1.972
2.484ValMet: 2.484 ± 1.547
4.969ValAsn: 4.969 ± 1.35
3.727ValPro: 3.727 ± 2.074
2.484ValGln: 2.484 ± 0.665
6.211ValArg: 6.211 ± 1.972
3.727ValSer: 3.727 ± 4.23
8.696ValThr: 8.696 ± 0.665
3.727ValVal: 3.727 ± 2.602
0.0ValTrp: 0.0 ± 0.0
1.242ValTyr: 1.242 ± 0.867
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
1.242TrpCys: 1.242 ± 0.955
1.242TrpAsp: 1.242 ± 0.955
0.0TrpGlu: 0.0 ± 0.0
1.242TrpPhe: 1.242 ± 0.955
1.242TrpGly: 1.242 ± 0.867
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
3.727TrpLeu: 3.727 ± 2.654
2.484TrpMet: 2.484 ± 2.01
1.242TrpAsn: 1.242 ± 0.867
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
2.484TrpSer: 2.484 ± 2.01
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.727TyrAla: 3.727 ± 1.215
1.242TyrCys: 1.242 ± 0.955
3.727TyrAsp: 3.727 ± 2.866
0.0TyrGlu: 0.0 ± 0.0
0.0TyrPhe: 0.0 ± 0.0
2.484TyrGly: 2.484 ± 1.911
0.0TyrHis: 0.0 ± 0.0
1.242TyrIle: 1.242 ± 0.955
1.242TyrLys: 1.242 ± 0.867
2.484TyrLeu: 2.484 ± 1.735
2.484TyrMet: 2.484 ± 0.665
0.0TyrAsn: 0.0 ± 0.0
2.484TyrPro: 2.484 ± 4.597
3.727TyrGln: 3.727 ± 1.399
2.484TyrArg: 2.484 ± 1.911
2.484TyrSer: 2.484 ± 4.597
2.484TyrThr: 2.484 ± 1.735
1.242TyrVal: 1.242 ± 0.955
2.484TyrTrp: 2.484 ± 0.665
1.242TyrTyr: 1.242 ± 0.867
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (806 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski