Amino acid dipepetide frequency for Macaca nemestrina herpesvirus 7

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.528AlaAla: 1.528 ± 0.214
1.095AlaCys: 1.095 ± 0.182
1.707AlaAsp: 1.707 ± 0.275
2.216AlaGlu: 2.216 ± 0.253
2.42AlaPhe: 2.42 ± 0.251
0.993AlaGly: 0.993 ± 0.175
1.019AlaHis: 1.019 ± 0.202
3.082AlaIle: 3.082 ± 0.313
2.191AlaLys: 2.191 ± 0.22
3.719AlaLeu: 3.719 ± 0.376
0.866AlaMet: 0.866 ± 0.168
2.14AlaAsn: 2.14 ± 0.249
1.248AlaPro: 1.248 ± 0.174
1.299AlaGln: 1.299 ± 0.207
1.095AlaArg: 1.095 ± 0.198
2.675AlaSer: 2.675 ± 0.27
2.471AlaThr: 2.471 ± 0.257
2.42AlaVal: 2.42 ± 0.265
0.331AlaTrp: 0.331 ± 0.104
1.325AlaTyr: 1.325 ± 0.184
0.0AlaXaa: 0.0 ± 0.0
Cys
0.993CysAla: 0.993 ± 0.173
0.535CysCys: 0.535 ± 0.131
1.197CysAsp: 1.197 ± 0.178
1.605CysGlu: 1.605 ± 0.219
1.477CysPhe: 1.477 ± 0.245
0.866CysGly: 0.866 ± 0.15
0.713CysHis: 0.713 ± 0.11
1.859CysIle: 1.859 ± 0.219
1.528CysLys: 1.528 ± 0.221
3.184CysLeu: 3.184 ± 0.371
0.484CysMet: 0.484 ± 0.1
1.63CysAsn: 1.63 ± 0.229
0.611CysPro: 0.611 ± 0.13
0.841CysGln: 0.841 ± 0.185
1.095CysArg: 1.095 ± 0.204
2.242CysSer: 2.242 ± 0.246
1.172CysThr: 1.172 ± 0.179
1.452CysVal: 1.452 ± 0.214
0.204CysTrp: 0.204 ± 0.064
0.866CysTyr: 0.866 ± 0.178
0.0CysXaa: 0.0 ± 0.0
Asp
1.783AspAla: 1.783 ± 0.216
1.197AspCys: 1.197 ± 0.148
2.063AspAsp: 2.063 ± 0.24
3.337AspGlu: 3.337 ± 0.291
3.999AspPhe: 3.999 ± 0.269
1.044AspGly: 1.044 ± 0.154
0.688AspHis: 0.688 ± 0.111
4.228AspIle: 4.228 ± 0.269
2.42AspLys: 2.42 ± 0.284
5.655AspLeu: 5.655 ± 0.406
1.146AspMet: 1.146 ± 0.147
2.904AspAsn: 2.904 ± 0.231
1.859AspPro: 1.859 ± 0.249
1.579AspGln: 1.579 ± 0.193
1.859AspArg: 1.859 ± 0.231
4.356AspSer: 4.356 ± 0.486
2.598AspThr: 2.598 ± 0.288
3.235AspVal: 3.235 ± 0.249
0.28AspTrp: 0.28 ± 0.082
1.681AspTyr: 1.681 ± 0.233
0.0AspXaa: 0.0 ± 0.0
Glu
1.834GluAla: 1.834 ± 0.251
1.35GluCys: 1.35 ± 0.191
2.522GluAsp: 2.522 ± 0.3
3.897GluGlu: 3.897 ± 0.361
3.159GluPhe: 3.159 ± 0.238
1.477GluGly: 1.477 ± 0.22
1.63GluHis: 1.63 ± 0.193
6.241GluIle: 6.241 ± 0.375
5.757GluLys: 5.757 ± 0.391
5.349GluLeu: 5.349 ± 0.379
1.656GluMet: 1.656 ± 0.182
6.292GluAsn: 6.292 ± 0.687
1.707GluPro: 1.707 ± 0.235
2.42GluGln: 2.42 ± 0.294
1.936GluArg: 1.936 ± 0.257
4.407GluSer: 4.407 ± 0.318
4.712GluThr: 4.712 ± 0.406
1.961GluVal: 1.961 ± 0.277
0.306GluTrp: 0.306 ± 0.093
2.445GluTyr: 2.445 ± 0.241
0.0GluXaa: 0.0 ± 0.0
Phe
2.522PheAla: 2.522 ± 0.254
1.732PheCys: 1.732 ± 0.235
2.573PheAsp: 2.573 ± 0.242
3.362PheGlu: 3.362 ± 0.308
4.687PhePhe: 4.687 ± 0.381
2.293PheGly: 2.293 ± 0.241
1.299PheHis: 1.299 ± 0.217
4.789PheIle: 4.789 ± 0.384
4.56PheLys: 4.56 ± 0.324
7.616PheLeu: 7.616 ± 0.54
1.299PheMet: 1.299 ± 0.174
4.025PheAsn: 4.025 ± 0.291
2.853PhePro: 2.853 ± 0.235
2.165PheGln: 2.165 ± 0.242
1.961PheArg: 1.961 ± 0.238
5.859PheSer: 5.859 ± 0.441
3.439PheThr: 3.439 ± 0.238
3.362PheVal: 3.362 ± 0.301
0.535PheTrp: 0.535 ± 0.126
2.777PheTyr: 2.777 ± 0.231
0.0PheXaa: 0.0 ± 0.0
Gly
1.35GlyAla: 1.35 ± 0.222
0.611GlyCys: 0.611 ± 0.149
1.07GlyAsp: 1.07 ± 0.163
1.554GlyGlu: 1.554 ± 0.205
2.089GlyPhe: 2.089 ± 0.248
1.044GlyGly: 1.044 ± 0.153
0.917GlyHis: 0.917 ± 0.141
2.573GlyIle: 2.573 ± 0.288
2.955GlyLys: 2.955 ± 0.226
3.821GlyLeu: 3.821 ± 0.341
0.688GlyMet: 0.688 ± 0.161
2.369GlyAsn: 2.369 ± 0.258
0.968GlyPro: 0.968 ± 0.2
1.07GlyGln: 1.07 ± 0.174
1.146GlyArg: 1.146 ± 0.219
2.242GlySer: 2.242 ± 0.264
1.681GlyThr: 1.681 ± 0.227
1.758GlyVal: 1.758 ± 0.26
0.408GlyTrp: 0.408 ± 0.096
1.376GlyTyr: 1.376 ± 0.172
0.0GlyXaa: 0.0 ± 0.0
His
1.019HisAla: 1.019 ± 0.14
0.509HisCys: 0.509 ± 0.138
1.172HisAsp: 1.172 ± 0.158
1.299HisGlu: 1.299 ± 0.172
1.936HisPhe: 1.936 ± 0.209
1.019HisGly: 1.019 ± 0.172
0.56HisHis: 0.56 ± 0.122
1.961HisIle: 1.961 ± 0.239
1.426HisLys: 1.426 ± 0.225
2.751HisLeu: 2.751 ± 0.266
0.56HisMet: 0.56 ± 0.113
1.376HisAsn: 1.376 ± 0.163
1.019HisPro: 1.019 ± 0.143
0.764HisGln: 0.764 ± 0.128
1.197HisArg: 1.197 ± 0.252
1.63HisSer: 1.63 ± 0.186
1.35HisThr: 1.35 ± 0.189
1.376HisVal: 1.376 ± 0.178
0.153HisTrp: 0.153 ± 0.055
0.866HisTyr: 0.866 ± 0.142
0.0HisXaa: 0.0 ± 0.0
Ile
2.98IleAla: 2.98 ± 0.286
2.343IleCys: 2.343 ± 0.229
4.33IleAsp: 4.33 ± 0.366
5.528IleGlu: 5.528 ± 0.42
4.942IlePhe: 4.942 ± 0.36
2.675IleGly: 2.675 ± 0.357
1.707IleHis: 1.707 ± 0.225
6.903IleIle: 6.903 ± 0.586
6.088IleLys: 6.088 ± 0.415
9.934IleLeu: 9.934 ± 0.47
1.834IleMet: 1.834 ± 0.276
5.502IleAsn: 5.502 ± 0.417
3.388IlePro: 3.388 ± 0.31
3.795IleGln: 3.795 ± 0.333
2.904IleArg: 2.904 ± 0.235
7.183IleSer: 7.183 ± 0.458
4.916IleThr: 4.916 ± 0.314
4.025IleVal: 4.025 ± 0.312
0.611IleTrp: 0.611 ± 0.119
3.999IleTyr: 3.999 ± 0.262
0.0IleXaa: 0.0 ± 0.0
Lys
1.859LysAla: 1.859 ± 0.227
1.707LysCys: 1.707 ± 0.246
3.872LysAsp: 3.872 ± 0.366
4.687LysGlu: 4.687 ± 0.375
3.795LysPhe: 3.795 ± 0.351
1.477LysGly: 1.477 ± 0.209
2.191LysHis: 2.191 ± 0.279
7.209LysIle: 7.209 ± 0.431
7.158LysLys: 7.158 ± 0.571
6.419LysLeu: 6.419 ± 0.429
1.477LysMet: 1.477 ± 0.144
7.03LysAsn: 7.03 ± 0.442
1.961LysPro: 1.961 ± 0.199
3.541LysGln: 3.541 ± 0.341
3.362LysArg: 3.362 ± 0.301
5.196LysSer: 5.196 ± 0.469
6.164LysThr: 6.164 ± 0.383
2.675LysVal: 2.675 ± 0.257
0.535LysTrp: 0.535 ± 0.108
2.649LysTyr: 2.649 ± 0.186
0.0LysXaa: 0.0 ± 0.0
Leu
4.254LeuAla: 4.254 ± 0.353
3.286LeuCys: 3.286 ± 0.322
4.152LeuAsp: 4.152 ± 0.289
5.833LeuGlu: 5.833 ± 0.393
6.419LeuPhe: 6.419 ± 0.418
3.541LeuGly: 3.541 ± 0.464
3.031LeuHis: 3.031 ± 0.297
8.049LeuIle: 8.049 ± 0.462
8.38LeuLys: 8.38 ± 0.422
10.953LeuLeu: 10.953 ± 0.699
1.961LeuMet: 1.961 ± 0.249
7.311LeuAsn: 7.311 ± 0.497
4.305LeuPro: 4.305 ± 0.299
4.305LeuGln: 4.305 ± 0.358
3.643LeuArg: 3.643 ± 0.278
8.966LeuSer: 8.966 ± 0.563
6.546LeuThr: 6.546 ± 0.437
4.228LeuVal: 4.228 ± 0.337
0.815LeuTrp: 0.815 ± 0.146
4.814LeuTyr: 4.814 ± 0.275
0.0LeuXaa: 0.0 ± 0.0
Met
0.917MetAla: 0.917 ± 0.115
0.484MetCys: 0.484 ± 0.127
1.376MetAsp: 1.376 ± 0.19
1.477MetGlu: 1.477 ± 0.198
1.554MetPhe: 1.554 ± 0.222
0.637MetGly: 0.637 ± 0.152
0.509MetHis: 0.509 ± 0.127
1.248MetIle: 1.248 ± 0.17
1.376MetLys: 1.376 ± 0.183
2.522MetLeu: 2.522 ± 0.229
0.408MetMet: 0.408 ± 0.105
1.452MetAsn: 1.452 ± 0.22
0.688MetPro: 0.688 ± 0.15
1.172MetGln: 1.172 ± 0.183
0.841MetArg: 0.841 ± 0.156
1.809MetSer: 1.809 ± 0.194
1.35MetThr: 1.35 ± 0.201
0.866MetVal: 0.866 ± 0.161
0.229MetTrp: 0.229 ± 0.072
1.07MetTyr: 1.07 ± 0.155
0.0MetXaa: 0.0 ± 0.0
Asn
2.165AsnAla: 2.165 ± 0.278
1.477AsnCys: 1.477 ± 0.195
3.133AsnAsp: 3.133 ± 0.287
4.56AsnGlu: 4.56 ± 0.339
4.33AsnPhe: 4.33 ± 0.329
2.802AsnGly: 2.802 ± 0.284
1.859AsnHis: 1.859 ± 0.216
6.878AsnIle: 6.878 ± 0.371
4.661AsnLys: 4.661 ± 0.37
7.489AsnLeu: 7.489 ± 0.461
2.089AsnMet: 2.089 ± 0.182
4.993AsnAsn: 4.993 ± 0.539
2.267AsnPro: 2.267 ± 0.243
2.293AsnGln: 2.293 ± 0.257
2.547AsnArg: 2.547 ± 0.223
6.088AsnSer: 6.088 ± 0.521
4.101AsnThr: 4.101 ± 0.374
4.942AsnVal: 4.942 ± 0.331
0.382AsnTrp: 0.382 ± 0.106
2.751AsnTyr: 2.751 ± 0.262
0.0AsnXaa: 0.0 ± 0.0
Pro
0.917ProAla: 0.917 ± 0.154
0.917ProCys: 0.917 ± 0.156
1.605ProAsp: 1.605 ± 0.204
2.573ProGlu: 2.573 ± 0.24
2.14ProPhe: 2.14 ± 0.212
1.146ProGly: 1.146 ± 0.192
0.764ProHis: 0.764 ± 0.165
3.795ProIle: 3.795 ± 0.294
2.726ProLys: 2.726 ± 0.302
3.617ProLeu: 3.617 ± 0.33
0.662ProMet: 0.662 ± 0.19
2.42ProAsn: 2.42 ± 0.267
0.968ProPro: 0.968 ± 0.185
1.044ProGln: 1.044 ± 0.187
1.554ProArg: 1.554 ± 0.258
2.547ProSer: 2.547 ± 0.211
2.012ProThr: 2.012 ± 0.21
1.987ProVal: 1.987 ± 0.215
0.408ProTrp: 0.408 ± 0.134
1.248ProTyr: 1.248 ± 0.175
0.0ProXaa: 0.0 ± 0.0
Gln
0.942GlnAla: 0.942 ± 0.154
0.662GlnCys: 0.662 ± 0.15
1.426GlnAsp: 1.426 ± 0.207
2.394GlnGlu: 2.394 ± 0.332
1.961GlnPhe: 1.961 ± 0.192
0.815GlnGly: 0.815 ± 0.134
0.866GlnHis: 0.866 ± 0.171
3.821GlnIle: 3.821 ± 0.338
3.948GlnLys: 3.948 ± 0.319
3.515GlnLeu: 3.515 ± 0.276
0.79GlnMet: 0.79 ± 0.11
3.617GlnAsn: 3.617 ± 0.344
0.993GlnPro: 0.993 ± 0.147
1.528GlnGln: 1.528 ± 0.234
1.707GlnArg: 1.707 ± 0.246
2.42GlnSer: 2.42 ± 0.299
2.904GlnThr: 2.904 ± 0.272
1.503GlnVal: 1.503 ± 0.168
0.153GlnTrp: 0.153 ± 0.061
1.503GlnTyr: 1.503 ± 0.201
0.0GlnXaa: 0.0 ± 0.0
Arg
1.299ArgAla: 1.299 ± 0.2
0.892ArgCys: 0.892 ± 0.163
2.191ArgAsp: 2.191 ± 0.257
2.038ArgGlu: 2.038 ± 0.261
2.751ArgPhe: 2.751 ± 0.261
1.528ArgGly: 1.528 ± 0.272
1.172ArgHis: 1.172 ± 0.176
2.369ArgIle: 2.369 ± 0.215
3.159ArgLys: 3.159 ± 0.287
3.566ArgLeu: 3.566 ± 0.379
0.815ArgMet: 0.815 ± 0.127
2.42ArgAsn: 2.42 ± 0.27
1.299ArgPro: 1.299 ± 0.237
1.325ArgGln: 1.325 ± 0.223
1.783ArgArg: 1.783 ± 0.304
2.955ArgSer: 2.955 ± 0.396
1.528ArgThr: 1.528 ± 0.191
1.859ArgVal: 1.859 ± 0.239
0.331ArgTrp: 0.331 ± 0.105
1.63ArgTyr: 1.63 ± 0.175
0.0ArgXaa: 0.0 ± 0.0
Ser
3.006SerAla: 3.006 ± 0.306
1.758SerCys: 1.758 ± 0.243
4.789SerAsp: 4.789 ± 0.613
5.196SerGlu: 5.196 ± 0.451
4.865SerPhe: 4.865 ± 0.341
2.726SerGly: 2.726 ± 0.315
1.477SerHis: 1.477 ± 0.179
6.725SerIle: 6.725 ± 0.411
5.4SerLys: 5.4 ± 0.424
8.33SerLeu: 8.33 ± 0.459
1.707SerMet: 1.707 ± 0.229
5.655SerAsn: 5.655 ± 0.431
2.726SerPro: 2.726 ± 0.298
2.649SerGln: 2.649 ± 0.314
2.726SerArg: 2.726 ± 0.354
6.903SerSer: 6.903 ± 0.696
5.196SerThr: 5.196 ± 0.414
5.018SerVal: 5.018 ± 0.374
0.662SerTrp: 0.662 ± 0.112
2.42SerTyr: 2.42 ± 0.24
0.0SerXaa: 0.0 ± 0.0
Thr
2.496ThrAla: 2.496 ± 0.291
1.758ThrCys: 1.758 ± 0.249
3.515ThrAsp: 3.515 ± 0.361
4.025ThrGlu: 4.025 ± 0.336
3.923ThrPhe: 3.923 ± 0.239
2.242ThrGly: 2.242 ± 0.255
1.477ThrHis: 1.477 ± 0.162
5.12ThrIle: 5.12 ± 0.346
4.458ThrLys: 4.458 ± 0.299
5.782ThrLeu: 5.782 ± 0.387
1.299ThrMet: 1.299 ± 0.173
3.846ThrAsn: 3.846 ± 0.333
2.165ThrPro: 2.165 ± 0.264
2.14ThrGln: 2.14 ± 0.286
2.012ThrArg: 2.012 ± 0.257
4.381ThrSer: 4.381 ± 0.3
3.515ThrThr: 3.515 ± 0.314
4.585ThrVal: 4.585 ± 0.306
0.637ThrTrp: 0.637 ± 0.131
2.802ThrTyr: 2.802 ± 0.287
0.0ThrXaa: 0.0 ± 0.0
Val
1.91ValAla: 1.91 ± 0.205
1.248ValCys: 1.248 ± 0.203
2.777ValAsp: 2.777 ± 0.287
2.827ValGlu: 2.827 ± 0.238
4.177ValPhe: 4.177 ± 0.314
1.503ValGly: 1.503 ± 0.199
1.197ValHis: 1.197 ± 0.171
3.923ValIle: 3.923 ± 0.313
3.235ValLys: 3.235 ± 0.287
6.037ValLeu: 6.037 ± 0.376
1.248ValMet: 1.248 ± 0.14
3.337ValAsn: 3.337 ± 0.234
2.318ValPro: 2.318 ± 0.265
1.91ValGln: 1.91 ± 0.236
1.961ValArg: 1.961 ± 0.265
4.076ValSer: 4.076 ± 0.286
3.668ValThr: 3.668 ± 0.335
2.42ValVal: 2.42 ± 0.324
0.28ValTrp: 0.28 ± 0.074
2.343ValTyr: 2.343 ± 0.265
0.0ValXaa: 0.0 ± 0.0
Trp
0.204TrpAla: 0.204 ± 0.075
0.178TrpCys: 0.178 ± 0.064
0.127TrpAsp: 0.127 ± 0.055
0.408TrpGlu: 0.408 ± 0.102
0.535TrpPhe: 0.535 ± 0.102
0.255TrpGly: 0.255 ± 0.081
0.229TrpHis: 0.229 ± 0.086
0.892TrpIle: 0.892 ± 0.144
0.586TrpLys: 0.586 ± 0.136
0.764TrpLeu: 0.764 ± 0.136
0.102TrpMet: 0.102 ± 0.048
0.509TrpAsn: 0.509 ± 0.111
0.586TrpPro: 0.586 ± 0.148
0.306TrpGln: 0.306 ± 0.073
0.255TrpArg: 0.255 ± 0.108
0.459TrpSer: 0.459 ± 0.116
0.688TrpThr: 0.688 ± 0.142
0.306TrpVal: 0.306 ± 0.077
0.025TrpTrp: 0.025 ± 0.025
0.28TrpTyr: 0.28 ± 0.079
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.859TyrAla: 1.859 ± 0.224
0.815TyrCys: 0.815 ± 0.124
2.318TyrAsp: 2.318 ± 0.209
2.242TyrGlu: 2.242 ± 0.24
2.547TyrPhe: 2.547 ± 0.28
1.605TyrGly: 1.605 ± 0.185
0.637TyrHis: 0.637 ± 0.1
3.923TyrIle: 3.923 ± 0.339
2.955TyrLys: 2.955 ± 0.299
3.77TyrLeu: 3.77 ± 0.312
0.866TyrMet: 0.866 ± 0.12
2.98TyrAsn: 2.98 ± 0.342
1.121TyrPro: 1.121 ± 0.161
1.325TyrGln: 1.325 ± 0.179
1.325TyrArg: 1.325 ± 0.214
3.566TyrSer: 3.566 ± 0.327
2.165TyrThr: 2.165 ± 0.226
2.42TyrVal: 2.42 ± 0.257
0.408TyrTrp: 0.408 ± 0.111
1.681TyrTyr: 1.681 ± 0.22
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 83 proteins (39259 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski