Amino acid dipepetide frequency for CRESS virus sp. ctxk12

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
16.593AlaAla: 16.593 ± 0.852
0.0AlaCys: 0.0 ± 0.0
5.531AlaAsp: 5.531 ± 1.377
5.531AlaGlu: 5.531 ± 1.377
2.212AlaPhe: 2.212 ± 1.442
7.743AlaGly: 7.743 ± 1.726
1.106AlaHis: 1.106 ± 0.94
3.319AlaIle: 3.319 ± 1.158
1.106AlaLys: 1.106 ± 0.94
7.743AlaLeu: 7.743 ± 1.726
2.212AlaMet: 2.212 ± 1.88
4.425AlaAsn: 4.425 ± 2.885
5.531AlaPro: 5.531 ± 3.606
3.319AlaGln: 3.319 ± 1.158
7.743AlaArg: 7.743 ± 0.065
6.637AlaSer: 6.637 ± 1.005
1.106AlaThr: 1.106 ± 0.94
2.212AlaVal: 2.212 ± 0.219
2.212AlaTrp: 2.212 ± 1.88
2.212AlaTyr: 2.212 ± 0.219
0.0AlaXaa: 0.0 ± 0.0
Cys
1.106CysAla: 1.106 ± 0.94
0.0CysCys: 0.0 ± 0.0
1.106CysAsp: 1.106 ± 0.721
1.106CysGlu: 1.106 ± 0.721
0.0CysPhe: 0.0 ± 0.0
2.212CysGly: 2.212 ± 1.88
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
1.106CysLeu: 1.106 ± 0.94
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.106CysPro: 1.106 ± 0.94
0.0CysGln: 0.0 ± 0.0
1.106CysArg: 1.106 ± 0.94
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
1.106CysVal: 1.106 ± 0.721
0.0CysTrp: 0.0 ± 0.0
1.106CysTyr: 1.106 ± 0.94
0.0CysXaa: 0.0 ± 0.0
Asp
3.319AspAla: 3.319 ± 1.158
1.106AspCys: 1.106 ± 0.94
3.319AspAsp: 3.319 ± 2.82
3.319AspGlu: 3.319 ± 2.82
3.319AspPhe: 3.319 ± 1.158
5.531AspGly: 5.531 ± 3.038
1.106AspHis: 1.106 ± 0.94
2.212AspIle: 2.212 ± 0.219
3.319AspLys: 3.319 ± 1.158
4.425AspLeu: 4.425 ± 2.098
2.212AspMet: 2.212 ± 1.88
0.0AspAsn: 0.0 ± 0.0
2.212AspPro: 2.212 ± 1.88
2.212AspGln: 2.212 ± 1.442
2.212AspArg: 2.212 ± 0.219
6.637AspSer: 6.637 ± 1.005
4.425AspThr: 4.425 ± 0.437
4.425AspVal: 4.425 ± 2.885
0.0AspTrp: 0.0 ± 0.0
2.212AspTyr: 2.212 ± 1.442
0.0AspXaa: 0.0 ± 0.0
Glu
7.743GluAla: 7.743 ± 3.257
0.0GluCys: 0.0 ± 0.0
4.425GluAsp: 4.425 ± 2.098
3.319GluGlu: 3.319 ± 2.82
3.319GluPhe: 3.319 ± 1.158
3.319GluGly: 3.319 ± 1.158
2.212GluHis: 2.212 ± 0.219
0.0GluIle: 0.0 ± 0.0
2.212GluLys: 2.212 ± 1.88
2.212GluLeu: 2.212 ± 0.219
1.106GluMet: 1.106 ± 0.515
0.0GluAsn: 0.0 ± 0.0
1.106GluPro: 1.106 ± 0.721
2.212GluGln: 2.212 ± 0.219
4.425GluArg: 4.425 ± 0.437
0.0GluSer: 0.0 ± 0.0
0.0GluThr: 0.0 ± 0.0
1.106GluVal: 1.106 ± 0.721
2.212GluTrp: 2.212 ± 1.88
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.0PheCys: 0.0 ± 0.0
1.106PheAsp: 1.106 ± 0.94
2.212PheGlu: 2.212 ± 0.219
2.212PhePhe: 2.212 ± 1.442
5.531PheGly: 5.531 ± 1.945
3.319PheHis: 3.319 ± 1.158
1.106PheIle: 1.106 ± 0.94
3.319PheLys: 3.319 ± 0.503
1.106PheLeu: 1.106 ± 0.721
1.106PheMet: 1.106 ± 0.721
1.106PheAsn: 1.106 ± 0.94
0.0PhePro: 0.0 ± 0.0
1.106PheGln: 1.106 ± 0.721
7.743PheArg: 7.743 ± 3.387
4.425PheSer: 4.425 ± 1.224
4.425PheThr: 4.425 ± 1.224
1.106PheVal: 1.106 ± 0.721
1.106PheTrp: 1.106 ± 0.721
1.106PheTyr: 1.106 ± 0.721
0.0PheXaa: 0.0 ± 0.0
Gly
8.85GlyAla: 8.85 ± 4.108
1.106GlyCys: 1.106 ± 0.94
5.531GlyAsp: 5.531 ± 1.377
2.212GlyGlu: 2.212 ± 1.88
0.0GlyPhe: 0.0 ± 0.0
16.593GlyGly: 16.593 ± 7.453
3.319GlyHis: 3.319 ± 0.503
4.425GlyIle: 4.425 ± 1.224
5.531GlyLys: 5.531 ± 3.038
9.956GlyLeu: 9.956 ± 1.508
3.319GlyMet: 3.319 ± 0.503
2.212GlyAsn: 2.212 ± 0.219
5.531GlyPro: 5.531 ± 3.038
8.85GlyGln: 8.85 ± 0.786
5.531GlyArg: 5.531 ± 0.284
5.531GlySer: 5.531 ± 3.038
5.531GlyThr: 5.531 ± 0.284
4.425GlyVal: 4.425 ± 2.885
0.0GlyTrp: 0.0 ± 0.0
5.531GlyTyr: 5.531 ± 0.284
0.0GlyXaa: 0.0 ± 0.0
His
1.106HisAla: 1.106 ± 0.94
0.0HisCys: 0.0 ± 0.0
1.106HisAsp: 1.106 ± 0.721
0.0HisGlu: 0.0 ± 0.0
2.212HisPhe: 2.212 ± 1.88
3.319HisGly: 3.319 ± 1.158
0.0HisHis: 0.0 ± 0.0
1.106HisIle: 1.106 ± 0.94
2.212HisLys: 2.212 ± 1.442
3.319HisLeu: 3.319 ± 2.82
1.106HisMet: 1.106 ± 0.94
0.0HisAsn: 0.0 ± 0.0
3.319HisPro: 3.319 ± 2.164
2.212HisGln: 2.212 ± 1.442
3.319HisArg: 3.319 ± 0.503
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
2.212HisVal: 2.212 ± 0.219
0.0HisTrp: 0.0 ± 0.0
1.106HisTyr: 1.106 ± 0.721
0.0HisXaa: 0.0 ± 0.0
Ile
6.637IleAla: 6.637 ± 2.317
0.0IleCys: 0.0 ± 0.0
1.106IleAsp: 1.106 ± 0.94
3.319IleGlu: 3.319 ± 2.82
2.212IlePhe: 2.212 ± 0.219
3.319IleGly: 3.319 ± 2.164
2.212IleHis: 2.212 ± 1.88
1.106IleIle: 1.106 ± 0.94
2.212IleLys: 2.212 ± 1.88
1.106IleLeu: 1.106 ± 0.94
1.106IleMet: 1.106 ± 0.721
1.106IleAsn: 1.106 ± 0.94
2.212IlePro: 2.212 ± 0.219
0.0IleGln: 0.0 ± 0.0
3.319IleArg: 3.319 ± 0.503
3.319IleSer: 3.319 ± 2.164
1.106IleThr: 1.106 ± 0.94
1.106IleVal: 1.106 ± 0.94
1.106IleTrp: 1.106 ± 0.721
2.212IleTyr: 2.212 ± 0.219
0.0IleXaa: 0.0 ± 0.0
Lys
2.212LysAla: 2.212 ± 1.88
1.106LysCys: 1.106 ± 0.94
4.425LysAsp: 4.425 ± 2.098
3.319LysGlu: 3.319 ± 2.82
2.212LysPhe: 2.212 ± 1.442
3.319LysGly: 3.319 ± 0.503
1.106LysHis: 1.106 ± 0.721
3.319LysIle: 3.319 ± 1.158
0.0LysLys: 0.0 ± 0.0
4.425LysLeu: 4.425 ± 0.437
0.0LysMet: 0.0 ± 0.0
1.106LysAsn: 1.106 ± 0.721
1.106LysPro: 1.106 ± 0.721
0.0LysGln: 0.0 ± 0.0
5.531LysArg: 5.531 ± 1.377
3.319LysSer: 3.319 ± 1.158
2.212LysThr: 2.212 ± 0.219
1.106LysVal: 1.106 ± 0.721
0.0LysTrp: 0.0 ± 0.0
3.319LysTyr: 3.319 ± 0.503
0.0LysXaa: 0.0 ± 0.0
Leu
4.425LeuAla: 4.425 ± 2.098
0.0LeuCys: 0.0 ± 0.0
8.85LeuAsp: 8.85 ± 2.536
1.106LeuGlu: 1.106 ± 0.94
1.106LeuPhe: 1.106 ± 0.721
9.956LeuGly: 9.956 ± 3.169
2.212LeuHis: 2.212 ± 0.219
2.212LeuIle: 2.212 ± 0.219
5.531LeuLys: 5.531 ± 1.377
4.425LeuLeu: 4.425 ± 2.098
0.0LeuMet: 0.0 ± 0.0
4.425LeuAsn: 4.425 ± 1.224
6.637LeuPro: 6.637 ± 2.317
2.212LeuGln: 2.212 ± 1.88
3.319LeuArg: 3.319 ± 0.503
3.319LeuSer: 3.319 ± 2.164
3.319LeuThr: 3.319 ± 0.503
3.319LeuVal: 3.319 ± 0.503
0.0LeuTrp: 0.0 ± 0.0
4.425LeuTyr: 4.425 ± 2.885
0.0LeuXaa: 0.0 ± 0.0
Met
1.106MetAla: 1.106 ± 0.94
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
1.106MetGlu: 1.106 ± 0.721
2.212MetPhe: 2.212 ± 1.88
0.0MetGly: 0.0 ± 0.0
1.106MetHis: 1.106 ± 0.721
0.0MetIle: 0.0 ± 0.0
1.106MetLys: 1.106 ± 0.94
2.212MetLeu: 2.212 ± 0.219
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
4.425MetPro: 4.425 ± 1.224
2.212MetGln: 2.212 ± 0.219
2.212MetArg: 2.212 ± 1.442
1.106MetSer: 1.106 ± 0.94
0.0MetThr: 0.0 ± 0.0
1.106MetVal: 1.106 ± 0.721
0.0MetTrp: 0.0 ± 0.0
1.106MetTyr: 1.106 ± 0.721
0.0MetXaa: 0.0 ± 0.0
Asn
2.212AsnAla: 2.212 ± 1.442
0.0AsnCys: 0.0 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
2.212AsnGlu: 2.212 ± 0.219
0.0AsnPhe: 0.0 ± 0.0
1.106AsnGly: 1.106 ± 0.94
2.212AsnHis: 2.212 ± 0.219
3.319AsnIle: 3.319 ± 0.503
2.212AsnLys: 2.212 ± 0.219
0.0AsnLeu: 0.0 ± 0.0
0.0AsnMet: 0.0 ± 0.0
1.106AsnAsn: 1.106 ± 0.94
0.0AsnPro: 0.0 ± 0.0
2.212AsnGln: 2.212 ± 1.442
0.0AsnArg: 0.0 ± 0.0
2.212AsnSer: 2.212 ± 1.442
2.212AsnThr: 2.212 ± 0.219
2.212AsnVal: 2.212 ± 1.442
1.106AsnTrp: 1.106 ± 0.721
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
4.425ProAla: 4.425 ± 1.224
1.106ProCys: 1.106 ± 0.94
2.212ProAsp: 2.212 ± 1.88
2.212ProGlu: 2.212 ± 0.219
2.212ProPhe: 2.212 ± 1.442
6.637ProGly: 6.637 ± 0.656
0.0ProHis: 0.0 ± 0.0
4.425ProIle: 4.425 ± 2.098
1.106ProLys: 1.106 ± 0.721
5.531ProLeu: 5.531 ± 1.945
1.106ProMet: 1.106 ± 0.721
0.0ProAsn: 0.0 ± 0.0
3.319ProPro: 3.319 ± 1.158
0.0ProGln: 0.0 ± 0.0
8.85ProArg: 8.85 ± 2.447
1.106ProSer: 1.106 ± 0.721
3.319ProThr: 3.319 ± 0.503
3.319ProVal: 3.319 ± 0.503
3.319ProTrp: 3.319 ± 1.158
3.319ProTyr: 3.319 ± 2.164
0.0ProXaa: 0.0 ± 0.0
Gln
2.212GlnAla: 2.212 ± 0.219
2.212GlnCys: 2.212 ± 1.442
2.212GlnAsp: 2.212 ± 0.219
0.0GlnGlu: 0.0 ± 0.0
2.212GlnPhe: 2.212 ± 1.442
4.425GlnGly: 4.425 ± 1.224
0.0GlnHis: 0.0 ± 0.0
2.212GlnIle: 2.212 ± 1.88
1.106GlnLys: 1.106 ± 0.94
2.212GlnLeu: 2.212 ± 1.442
1.106GlnMet: 1.106 ± 0.721
2.212GlnAsn: 2.212 ± 0.219
0.0GlnPro: 0.0 ± 0.0
1.106GlnGln: 1.106 ± 0.721
2.212GlnArg: 2.212 ± 0.219
3.319GlnSer: 3.319 ± 1.158
3.319GlnThr: 3.319 ± 1.158
2.212GlnVal: 2.212 ± 1.442
3.319GlnTrp: 3.319 ± 1.158
1.106GlnTyr: 1.106 ± 0.721
0.0GlnXaa: 0.0 ± 0.0
Arg
4.425ArgAla: 4.425 ± 1.224
0.0ArgCys: 0.0 ± 0.0
5.531ArgAsp: 5.531 ± 0.284
5.531ArgGlu: 5.531 ± 0.284
6.637ArgPhe: 6.637 ± 4.327
8.85ArgGly: 8.85 ± 7.519
2.212ArgHis: 2.212 ± 1.442
1.106ArgIle: 1.106 ± 0.94
7.743ArgLys: 7.743 ± 1.726
6.637ArgLeu: 6.637 ± 0.656
1.106ArgMet: 1.106 ± 0.721
1.106ArgAsn: 1.106 ± 0.721
6.637ArgPro: 6.637 ± 2.666
1.106ArgGln: 1.106 ± 0.94
25.442ArgArg: 25.442 ± 6.621
4.425ArgSer: 4.425 ± 2.885
3.319ArgThr: 3.319 ± 0.503
5.531ArgVal: 5.531 ± 0.284
2.212ArgTrp: 2.212 ± 1.88
3.319ArgTyr: 3.319 ± 2.164
0.0ArgXaa: 0.0 ± 0.0
Ser
5.531SerAla: 5.531 ± 0.284
0.0SerCys: 0.0 ± 0.0
4.425SerAsp: 4.425 ± 0.437
2.212SerGlu: 2.212 ± 0.219
3.319SerPhe: 3.319 ± 2.164
6.637SerGly: 6.637 ± 1.005
0.0SerHis: 0.0 ± 0.0
2.212SerIle: 2.212 ± 0.219
1.106SerLys: 1.106 ± 0.94
3.319SerLeu: 3.319 ± 1.158
1.106SerMet: 1.106 ± 0.721
0.0SerAsn: 0.0 ± 0.0
2.212SerPro: 2.212 ± 1.442
2.212SerGln: 2.212 ± 1.442
4.425SerArg: 4.425 ± 2.098
3.319SerSer: 3.319 ± 2.164
3.319SerThr: 3.319 ± 1.158
5.531SerVal: 5.531 ± 3.606
3.319SerTrp: 3.319 ± 0.503
4.425SerTyr: 4.425 ± 1.224
0.0SerXaa: 0.0 ± 0.0
Thr
5.531ThrAla: 5.531 ± 0.284
1.106ThrCys: 1.106 ± 0.94
1.106ThrAsp: 1.106 ± 0.94
1.106ThrGlu: 1.106 ± 0.721
3.319ThrPhe: 3.319 ± 0.503
3.319ThrGly: 3.319 ± 2.82
2.212ThrHis: 2.212 ± 1.88
2.212ThrIle: 2.212 ± 1.88
1.106ThrLys: 1.106 ± 0.721
4.425ThrLeu: 4.425 ± 1.224
0.0ThrMet: 0.0 ± 0.0
2.212ThrAsn: 2.212 ± 1.442
2.212ThrPro: 2.212 ± 1.442
1.106ThrGln: 1.106 ± 0.94
4.425ThrArg: 4.425 ± 0.437
3.319ThrSer: 3.319 ± 0.503
4.425ThrThr: 4.425 ± 3.759
1.106ThrVal: 1.106 ± 0.94
2.212ThrTrp: 2.212 ± 1.88
3.319ThrTyr: 3.319 ± 0.503
0.0ThrXaa: 0.0 ± 0.0
Val
5.531ValAla: 5.531 ± 3.606
0.0ValCys: 0.0 ± 0.0
2.212ValAsp: 2.212 ± 0.219
0.0ValGlu: 0.0 ± 0.0
0.0ValPhe: 0.0 ± 0.0
6.637ValGly: 6.637 ± 4.327
2.212ValHis: 2.212 ± 1.442
2.212ValIle: 2.212 ± 0.219
1.106ValLys: 1.106 ± 0.721
3.319ValLeu: 3.319 ± 0.503
2.212ValMet: 2.212 ± 1.045
0.0ValAsn: 0.0 ± 0.0
4.425ValPro: 4.425 ± 1.224
4.425ValGln: 4.425 ± 1.224
4.425ValArg: 4.425 ± 1.224
0.0ValSer: 0.0 ± 0.0
1.106ValThr: 1.106 ± 0.721
1.106ValVal: 1.106 ± 0.94
1.106ValTrp: 1.106 ± 0.721
4.425ValTyr: 4.425 ± 1.224
0.0ValXaa: 0.0 ± 0.0
Trp
2.212TrpAla: 2.212 ± 0.219
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
3.319TrpPhe: 3.319 ± 0.503
2.212TrpGly: 2.212 ± 0.219
1.106TrpHis: 1.106 ± 0.721
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
1.106TrpLeu: 1.106 ± 0.721
1.106TrpMet: 1.106 ± 0.94
1.106TrpAsn: 1.106 ± 0.721
0.0TrpPro: 0.0 ± 0.0
1.106TrpGln: 1.106 ± 0.94
2.212TrpArg: 2.212 ± 0.219
2.212TrpSer: 2.212 ± 1.88
6.637TrpThr: 6.637 ± 3.978
1.106TrpVal: 1.106 ± 0.721
0.0TrpTrp: 0.0 ± 0.0
2.212TrpTyr: 2.212 ± 0.219
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.319TyrAla: 3.319 ± 2.164
3.319TyrCys: 3.319 ± 1.158
3.319TyrAsp: 3.319 ± 2.164
1.106TyrGlu: 1.106 ± 0.721
1.106TyrPhe: 1.106 ± 0.721
3.319TyrGly: 3.319 ± 2.164
0.0TyrHis: 0.0 ± 0.0
3.319TyrIle: 3.319 ± 2.164
1.106TyrLys: 1.106 ± 0.721
2.212TyrLeu: 2.212 ± 0.219
0.0TyrMet: 0.0 ± 0.0
2.212TyrAsn: 2.212 ± 0.219
5.531TyrPro: 5.531 ± 1.377
1.106TyrGln: 1.106 ± 0.94
4.425TyrArg: 4.425 ± 2.885
4.425TyrSer: 4.425 ± 1.224
0.0TyrThr: 0.0 ± 0.0
2.212TyrVal: 2.212 ± 1.442
4.425TyrTrp: 4.425 ± 1.224
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (905 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski