Amino acid dipepetide frequency for Mycoplasma crocodyli (strain ATCC 51981 / MP145)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.894AlaAla: 2.894 ± 0.152
0.232AlaCys: 0.232 ± 0.03
2.293AlaAsp: 2.293 ± 0.115
2.611AlaGlu: 2.611 ± 0.112
2.58AlaPhe: 2.58 ± 0.126
2.663AlaGly: 2.663 ± 0.126
0.821AlaHis: 0.821 ± 0.056
5.184AlaIle: 5.184 ± 0.137
5.282AlaLys: 5.282 ± 0.145
5.376AlaLeu: 5.376 ± 0.166
1.096AlaMet: 1.096 ± 0.074
3.342AlaAsn: 3.342 ± 0.11
1.225AlaPro: 1.225 ± 0.087
1.539AlaGln: 1.539 ± 0.085
1.799AlaArg: 1.799 ± 0.098
3.322AlaSer: 3.322 ± 0.108
3.134AlaThr: 3.134 ± 0.122
2.301AlaVal: 2.301 ± 0.105
0.361AlaTrp: 0.361 ± 0.033
2.05AlaTyr: 2.05 ± 0.075
0.0AlaXaa: 0.0 ± 0.0
Cys
0.342CysAla: 0.342 ± 0.039
0.051CysCys: 0.051 ± 0.013
0.357CysAsp: 0.357 ± 0.038
0.302CysGlu: 0.302 ± 0.041
0.338CysPhe: 0.338 ± 0.039
0.397CysGly: 0.397 ± 0.032
0.114CysHis: 0.114 ± 0.021
0.408CysIle: 0.408 ± 0.042
0.412CysLys: 0.412 ± 0.042
0.467CysLeu: 0.467 ± 0.044
0.059CysMet: 0.059 ± 0.016
0.334CysAsn: 0.334 ± 0.038
0.141CysPro: 0.141 ± 0.022
0.122CysGln: 0.122 ± 0.021
0.118CysArg: 0.118 ± 0.02
0.412CysSer: 0.412 ± 0.047
0.22CysThr: 0.22 ± 0.031
0.251CysVal: 0.251 ± 0.032
0.063CysTrp: 0.063 ± 0.018
0.192CysTyr: 0.192 ± 0.029
0.0CysXaa: 0.0 ± 0.0
Asp
2.682AspAla: 2.682 ± 0.102
0.24AspCys: 0.24 ± 0.029
3.028AspAsp: 3.028 ± 0.12
4.732AspGlu: 4.732 ± 0.152
3.746AspPhe: 3.746 ± 0.15
2.623AspGly: 2.623 ± 0.117
0.742AspHis: 0.742 ± 0.051
4.913AspIle: 4.913 ± 0.14
6.319AspLys: 6.319 ± 0.191
5.973AspLeu: 5.973 ± 0.172
0.817AspMet: 0.817 ± 0.046
3.684AspAsn: 3.684 ± 0.132
1.535AspPro: 1.535 ± 0.088
1.5AspGln: 1.5 ± 0.07
1.335AspArg: 1.335 ± 0.069
3.255AspSer: 3.255 ± 0.123
2.49AspThr: 2.49 ± 0.116
3.409AspVal: 3.409 ± 0.123
0.459AspTrp: 0.459 ± 0.045
3.012AspTyr: 3.012 ± 0.126
0.0AspXaa: 0.0 ± 0.0
Glu
3.432GluAla: 3.432 ± 0.132
0.24GluCys: 0.24 ± 0.033
3.047GluAsp: 3.047 ± 0.101
4.85GluGlu: 4.85 ± 0.175
3.617GluPhe: 3.617 ± 0.135
2.733GluGly: 2.733 ± 0.109
0.888GluHis: 0.888 ± 0.058
6.743GluIle: 6.743 ± 0.232
7.469GluLys: 7.469 ± 0.211
7.976GluLeu: 7.976 ± 0.197
1.339GluMet: 1.339 ± 0.08
4.952GluAsn: 4.952 ± 0.135
1.367GluPro: 1.367 ± 0.08
2.317GluGln: 2.317 ± 0.102
1.787GluArg: 1.787 ± 0.081
3.197GluSer: 3.197 ± 0.112
3.664GluThr: 3.664 ± 0.135
3.794GluVal: 3.794 ± 0.128
0.632GluTrp: 0.632 ± 0.044
3.122GluTyr: 3.122 ± 0.15
0.0GluXaa: 0.0 ± 0.0
Phe
2.824PheAla: 2.824 ± 0.116
0.326PheCys: 0.326 ± 0.031
3.809PheAsp: 3.809 ± 0.123
3.471PheGlu: 3.471 ± 0.135
2.435PhePhe: 2.435 ± 0.141
2.737PheGly: 2.737 ± 0.117
0.636PheHis: 0.636 ± 0.044
5.172PheIle: 5.172 ± 0.212
5.38PheLys: 5.38 ± 0.154
4.763PheLeu: 4.763 ± 0.169
0.974PheMet: 0.974 ± 0.072
4.277PheAsn: 4.277 ± 0.138
1.268PhePro: 1.268 ± 0.074
1.049PheGln: 1.049 ± 0.068
1.319PheArg: 1.319 ± 0.076
3.974PheSer: 3.974 ± 0.144
2.623PheThr: 2.623 ± 0.102
3.252PheVal: 3.252 ± 0.123
0.483PheTrp: 0.483 ± 0.043
2.223PheTyr: 2.223 ± 0.108
0.0PheXaa: 0.0 ± 0.0
Gly
2.67GlyAla: 2.67 ± 0.12
0.291GlyCys: 0.291 ± 0.034
2.454GlyAsp: 2.454 ± 0.106
2.348GlyGlu: 2.348 ± 0.105
2.988GlyPhe: 2.988 ± 0.127
3.055GlyGly: 3.055 ± 0.155
0.844GlyHis: 0.844 ± 0.068
4.602GlyIle: 4.602 ± 0.158
4.591GlyLys: 4.591 ± 0.167
4.489GlyLeu: 4.489 ± 0.146
1.033GlyMet: 1.033 ± 0.058
2.741GlyAsn: 2.741 ± 0.116
0.958GlyPro: 0.958 ± 0.059
1.453GlyGln: 1.453 ± 0.085
1.606GlyArg: 1.606 ± 0.101
3.287GlySer: 3.287 ± 0.118
2.729GlyThr: 2.729 ± 0.11
3.181GlyVal: 3.181 ± 0.138
0.456GlyTrp: 0.456 ± 0.05
2.018GlyTyr: 2.018 ± 0.109
0.004GlyXaa: 0.004 ± 0.004
His
0.742HisAla: 0.742 ± 0.053
0.082HisCys: 0.082 ± 0.02
0.801HisAsp: 0.801 ± 0.054
1.013HisGlu: 1.013 ± 0.067
0.805HisPhe: 0.805 ± 0.055
0.864HisGly: 0.864 ± 0.073
0.259HisHis: 0.259 ± 0.034
1.296HisIle: 1.296 ± 0.068
1.272HisLys: 1.272 ± 0.072
1.445HisLeu: 1.445 ± 0.071
0.22HisMet: 0.22 ± 0.03
1.037HisAsn: 1.037 ± 0.059
0.514HisPro: 0.514 ± 0.053
0.44HisGln: 0.44 ± 0.044
0.401HisArg: 0.401 ± 0.04
0.903HisSer: 0.903 ± 0.066
0.664HisThr: 0.664 ± 0.051
0.742HisVal: 0.742 ± 0.049
0.137HisTrp: 0.137 ± 0.022
0.562HisTyr: 0.562 ± 0.049
0.0HisXaa: 0.0 ± 0.0
Ile
4.964IleAla: 4.964 ± 0.171
0.534IleCys: 0.534 ± 0.05
6.287IleAsp: 6.287 ± 0.198
6.472IleGlu: 6.472 ± 0.186
4.917IlePhe: 4.917 ± 0.21
4.493IleGly: 4.493 ± 0.169
1.257IleHis: 1.257 ± 0.07
8.828IleIle: 8.828 ± 0.268
10.273IleLys: 10.273 ± 0.256
8.05IleLeu: 8.05 ± 0.248
1.579IleMet: 1.579 ± 0.089
8.278IleAsn: 8.278 ± 0.205
2.835IlePro: 2.835 ± 0.118
2.266IleGln: 2.266 ± 0.099
2.356IleArg: 2.356 ± 0.107
7.143IleSer: 7.143 ± 0.197
5.305IleThr: 5.305 ± 0.15
5.235IleVal: 5.235 ± 0.158
0.715IleTrp: 0.715 ± 0.06
3.605IleTyr: 3.605 ± 0.147
0.012IleXaa: 0.012 ± 0.006
Lys
4.716LysAla: 4.716 ± 0.151
0.444LysCys: 0.444 ± 0.045
6.063LysAsp: 6.063 ± 0.16
8.714LysGlu: 8.714 ± 0.232
4.646LysPhe: 4.646 ± 0.129
3.888LysGly: 3.888 ± 0.144
1.59LysHis: 1.59 ± 0.077
10.411LysIle: 10.411 ± 0.24
11.196LysLys: 11.196 ± 0.228
9.488LysLeu: 9.488 ± 0.222
2.765LysMet: 2.765 ± 0.113
9.354LysAsn: 9.354 ± 0.222
2.698LysPro: 2.698 ± 0.115
2.988LysGln: 2.988 ± 0.104
2.859LysArg: 2.859 ± 0.118
6.456LysSer: 6.456 ± 0.178
6.495LysThr: 6.495 ± 0.2
5.757LysVal: 5.757 ± 0.174
1.127LysTrp: 1.127 ± 0.073
5.015LysTyr: 5.015 ± 0.168
0.004LysXaa: 0.004 ± 0.004
Leu
4.897LeuAla: 4.897 ± 0.156
0.526LeuCys: 0.526 ± 0.046
5.733LeuAsp: 5.733 ± 0.197
6.593LeuGlu: 6.593 ± 0.189
4.889LeuPhe: 4.889 ± 0.18
4.626LeuGly: 4.626 ± 0.157
1.19LeuHis: 1.19 ± 0.07
9.574LeuIle: 9.574 ± 0.283
9.468LeuLys: 9.468 ± 0.231
8.659LeuLeu: 8.659 ± 0.275
1.803LeuMet: 1.803 ± 0.091
7.646LeuAsn: 7.646 ± 0.165
2.623LeuPro: 2.623 ± 0.105
2.231LeuGln: 2.231 ± 0.089
2.706LeuArg: 2.706 ± 0.101
7.402LeuSer: 7.402 ± 0.195
5.07LeuThr: 5.07 ± 0.137
5.647LeuVal: 5.647 ± 0.179
0.726LeuTrp: 0.726 ± 0.059
3.342LeuTyr: 3.342 ± 0.119
0.0LeuXaa: 0.0 ± 0.0
Met
1.111MetAla: 1.111 ± 0.077
0.079MetCys: 0.079 ± 0.017
0.923MetAsp: 0.923 ± 0.062
0.891MetGlu: 0.891 ± 0.063
1.049MetPhe: 1.049 ± 0.073
0.891MetGly: 0.891 ± 0.065
0.318MetHis: 0.318 ± 0.033
1.861MetIle: 1.861 ± 0.099
2.066MetLys: 2.066 ± 0.086
1.94MetLeu: 1.94 ± 0.096
0.393MetMet: 0.393 ± 0.037
1.445MetAsn: 1.445 ± 0.079
0.664MetPro: 0.664 ± 0.054
0.522MetGln: 0.522 ± 0.047
0.499MetArg: 0.499 ± 0.05
1.386MetSer: 1.386 ± 0.078
0.939MetThr: 0.939 ± 0.066
1.029MetVal: 1.029 ± 0.06
0.134MetTrp: 0.134 ± 0.023
0.656MetTyr: 0.656 ± 0.05
0.0MetXaa: 0.0 ± 0.0
Asn
3.232AsnAla: 3.232 ± 0.132
0.31AsnCys: 0.31 ± 0.034
4.406AsnAsp: 4.406 ± 0.155
5.671AsnGlu: 5.671 ± 0.182
3.876AsnPhe: 3.876 ± 0.124
3.216AsnGly: 3.216 ± 0.129
1.166AsnHis: 1.166 ± 0.065
7.289AsnIle: 7.289 ± 0.216
9.425AsnLys: 9.425 ± 0.229
7.049AsnLeu: 7.049 ± 0.194
1.245AsnMet: 1.245 ± 0.084
7.198AsnAsn: 7.198 ± 0.221
2.231AsnPro: 2.231 ± 0.116
2.517AsnGln: 2.517 ± 0.101
1.759AsnArg: 1.759 ± 0.089
5.262AsnSer: 5.262 ± 0.169
3.589AsnThr: 3.589 ± 0.145
3.978AsnVal: 3.978 ± 0.118
0.719AsnTrp: 0.719 ± 0.057
3.44AsnTyr: 3.44 ± 0.17
0.0AsnXaa: 0.0 ± 0.0
Pro
1.335ProAla: 1.335 ± 0.091
0.098ProCys: 0.098 ± 0.018
1.386ProAsp: 1.386 ± 0.08
1.826ProGlu: 1.826 ± 0.1
1.418ProPhe: 1.418 ± 0.093
1.473ProGly: 1.473 ± 0.085
0.448ProHis: 0.448 ± 0.037
2.344ProIle: 2.344 ± 0.116
2.564ProLys: 2.564 ± 0.116
2.128ProLeu: 2.128 ± 0.1
0.385ProMet: 0.385 ± 0.048
2.125ProAsn: 2.125 ± 0.106
0.491ProPro: 0.491 ± 0.054
0.77ProGln: 0.77 ± 0.056
0.664ProArg: 0.664 ± 0.068
1.842ProSer: 1.842 ± 0.095
1.893ProThr: 1.893 ± 0.102
1.751ProVal: 1.751 ± 0.107
0.216ProTrp: 0.216 ± 0.03
1.21ProTyr: 1.21 ± 0.068
0.0ProXaa: 0.0 ± 0.0
Gln
1.41GlnAla: 1.41 ± 0.07
0.114GlnCys: 0.114 ± 0.018
1.469GlnAsp: 1.469 ± 0.077
2.121GlnGlu: 2.121 ± 0.076
1.194GlnPhe: 1.194 ± 0.074
1.186GlnGly: 1.186 ± 0.067
0.346GlnHis: 0.346 ± 0.033
2.623GlnIle: 2.623 ± 0.107
3.291GlnLys: 3.291 ± 0.111
2.549GlnLeu: 2.549 ± 0.097
0.597GlnMet: 0.597 ± 0.056
2.176GlnAsn: 2.176 ± 0.096
0.75GlnPro: 0.75 ± 0.069
0.864GlnGln: 0.864 ± 0.076
1.021GlnArg: 1.021 ± 0.065
1.551GlnSer: 1.551 ± 0.095
1.469GlnThr: 1.469 ± 0.082
1.571GlnVal: 1.571 ± 0.073
0.263GlnTrp: 0.263 ± 0.036
1.229GlnTyr: 1.229 ± 0.068
0.0GlnXaa: 0.0 ± 0.0
Arg
1.504ArgAla: 1.504 ± 0.094
0.157ArgCys: 0.157 ± 0.029
1.555ArgAsp: 1.555 ± 0.076
1.85ArgGlu: 1.85 ± 0.083
1.386ArgPhe: 1.386 ± 0.074
1.351ArgGly: 1.351 ± 0.078
0.393ArgHis: 0.393 ± 0.041
2.58ArgIle: 2.58 ± 0.094
2.792ArgLys: 2.792 ± 0.1
2.38ArgLeu: 2.38 ± 0.102
0.738ArgMet: 0.738 ± 0.056
2.077ArgAsn: 2.077 ± 0.097
0.679ArgPro: 0.679 ± 0.057
0.813ArgGln: 0.813 ± 0.065
1.088ArgArg: 1.088 ± 0.084
1.677ArgSer: 1.677 ± 0.081
1.449ArgThr: 1.449 ± 0.086
1.72ArgVal: 1.72 ± 0.086
0.263ArgTrp: 0.263 ± 0.038
1.233ArgTyr: 1.233 ± 0.08
0.0ArgXaa: 0.0 ± 0.0
Ser
3.142SerAla: 3.142 ± 0.103
0.499SerCys: 0.499 ± 0.047
3.507SerAsp: 3.507 ± 0.144
3.919SerGlu: 3.919 ± 0.124
4.135SerPhe: 4.135 ± 0.148
3.554SerGly: 3.554 ± 0.127
0.97SerHis: 0.97 ± 0.079
6.452SerIle: 6.452 ± 0.224
7.905SerLys: 7.905 ± 0.175
6.97SerLeu: 6.97 ± 0.208
1.052SerMet: 1.052 ± 0.066
4.885SerAsn: 4.885 ± 0.179
1.516SerPro: 1.516 ± 0.083
2.128SerGln: 2.128 ± 0.087
1.936SerArg: 1.936 ± 0.088
4.94SerSer: 4.94 ± 0.169
3.656SerThr: 3.656 ± 0.169
3.409SerVal: 3.409 ± 0.116
0.675SerTrp: 0.675 ± 0.049
3.059SerTyr: 3.059 ± 0.127
0.0SerXaa: 0.0 ± 0.0
Thr
2.254ThrAla: 2.254 ± 0.112
0.236ThrCys: 0.236 ± 0.03
2.553ThrAsp: 2.553 ± 0.098
2.816ThrGlu: 2.816 ± 0.124
3.087ThrPhe: 3.087 ± 0.121
2.666ThrGly: 2.666 ± 0.137
0.856ThrHis: 0.856 ± 0.054
5.604ThrIle: 5.604 ± 0.16
6.036ThrLys: 6.036 ± 0.196
5.321ThrLeu: 5.321 ± 0.16
0.789ThrMet: 0.789 ± 0.053
4.32ThrAsn: 4.32 ± 0.184
1.854ThrPro: 1.854 ± 0.096
1.374ThrGln: 1.374 ± 0.078
1.532ThrArg: 1.532 ± 0.077
4.104ThrSer: 4.104 ± 0.119
3.526ThrThr: 3.526 ± 0.149
2.647ThrVal: 2.647 ± 0.113
0.499ThrTrp: 0.499 ± 0.045
2.301ThrTyr: 2.301 ± 0.099
0.0ThrXaa: 0.0 ± 0.0
Val
3.507ValAla: 3.507 ± 0.151
0.342ValCys: 0.342 ± 0.035
3.578ValAsp: 3.578 ± 0.14
3.719ValGlu: 3.719 ± 0.125
2.981ValPhe: 2.981 ± 0.105
2.969ValGly: 2.969 ± 0.136
0.715ValHis: 0.715 ± 0.05
5.078ValIle: 5.078 ± 0.17
5.502ValLys: 5.502 ± 0.168
5.137ValLeu: 5.137 ± 0.164
1.033ValMet: 1.033 ± 0.067
3.735ValAsn: 3.735 ± 0.139
1.696ValPro: 1.696 ± 0.096
1.394ValGln: 1.394 ± 0.079
1.394ValArg: 1.394 ± 0.08
4.394ValSer: 4.394 ± 0.152
2.776ValThr: 2.776 ± 0.128
3.833ValVal: 3.833 ± 0.132
0.389ValTrp: 0.389 ± 0.037
2.011ValTyr: 2.011 ± 0.091
0.0ValXaa: 0.0 ± 0.0
Trp
0.452TrpAla: 0.452 ± 0.042
0.079TrpCys: 0.079 ± 0.019
0.483TrpAsp: 0.483 ± 0.042
0.542TrpGlu: 0.542 ± 0.048
0.503TrpPhe: 0.503 ± 0.039
0.393TrpGly: 0.393 ± 0.042
0.102TrpHis: 0.102 ± 0.023
0.864TrpIle: 0.864 ± 0.073
0.75TrpLys: 0.75 ± 0.058
0.978TrpLeu: 0.978 ± 0.059
0.216TrpMet: 0.216 ± 0.028
0.624TrpAsn: 0.624 ± 0.044
0.208TrpPro: 0.208 ± 0.028
0.216TrpGln: 0.216 ± 0.028
0.279TrpArg: 0.279 ± 0.032
0.617TrpSer: 0.617 ± 0.057
0.499TrpThr: 0.499 ± 0.053
0.514TrpVal: 0.514 ± 0.042
0.075TrpTrp: 0.075 ± 0.015
0.467TrpTyr: 0.467 ± 0.039
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.995TyrAla: 1.995 ± 0.087
0.224TyrCys: 0.224 ± 0.03
2.753TyrAsp: 2.753 ± 0.104
2.702TyrGlu: 2.702 ± 0.107
2.407TyrPhe: 2.407 ± 0.1
2.022TyrGly: 2.022 ± 0.094
0.546TyrHis: 0.546 ± 0.051
3.578TyrIle: 3.578 ± 0.158
4.685TyrLys: 4.685 ± 0.164
4.214TyrLeu: 4.214 ± 0.138
0.66TyrMet: 0.66 ± 0.044
3.35TyrAsn: 3.35 ± 0.115
1.111TyrPro: 1.111 ± 0.071
1.288TyrGln: 1.288 ± 0.065
1.229TyrArg: 1.229 ± 0.074
3.181TyrSer: 3.181 ± 0.112
2.183TyrThr: 2.183 ± 0.118
2.152TyrVal: 2.152 ± 0.096
0.467TyrTrp: 0.467 ± 0.045
2.007TyrTyr: 2.007 ± 0.098
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.008XaaAsp: 0.008 ± 0.006
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.004XaaSer: 0.004 ± 0.004
0.0XaaThr: 0.0 ± 0.0
0.008XaaVal: 0.008 ± 0.006
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 689 proteins (254647 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski