Amino acid dipepetide frequency for Ceraceosorus bombacis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	14.644AlaAla: 14.644 ± 0.104	1.111AlaCys: 1.111 ± 0.019	5.364AlaAsp: 5.364 ± 0.036	6.182AlaGlu: 6.182 ± 0.049	3.302AlaPhe: 3.302 ± 0.031	8.001AlaGly: 8.001 ± 0.054	2.828AlaHis: 2.828 ± 0.025	3.934AlaIle: 3.934 ± 0.037	4.733AlaLys: 4.733 ± 0.041	10.165AlaLeu: 10.165 ± 0.066	2.078AlaMet: 2.078 ± 0.026	3.246AlaAsn: 3.246 ± 0.032	7.045AlaPro: 7.045 ± 0.057	5.197AlaGln: 5.197 ± 0.044	7.689AlaArg: 7.689 ± 0.053	12.411AlaSer: 12.411 ± 0.098	6.236AlaThr: 6.236 ± 0.047	5.738AlaVal: 5.738 ± 0.041	1.356AlaTrp: 1.356 ± 0.02	2.136AlaTyr: 2.136 ± 0.028	0.004AlaXaa: 0.004 ± 0.001
Cys	1.045CysAla: 1.045 ± 0.018	0.19CysCys: 0.19 ± 0.008	0.55CysAsp: 0.55 ± 0.013	0.526CysGlu: 0.526 ± 0.012	0.408CysPhe: 0.408 ± 0.011	0.764CysGly: 0.764 ± 0.017	0.251CysHis: 0.251 ± 0.009	0.499CysIle: 0.499 ± 0.012	0.435CysLys: 0.435 ± 0.011	0.977CysLeu: 0.977 ± 0.018	0.208CysMet: 0.208 ± 0.007	0.325CysAsn: 0.325 ± 0.01	0.564CysPro: 0.564 ± 0.016	0.343CysGln: 0.343 ± 0.01	0.609CysArg: 0.609 ± 0.012	0.842CysSer: 0.842 ± 0.016	0.591CysThr: 0.591 ± 0.013	0.649CysVal: 0.649 ± 0.015	0.155CysTrp: 0.155 ± 0.007	0.245CysTyr: 0.245 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	6.9AspAla: 6.9 ± 0.047	0.499AspCys: 0.499 ± 0.013	3.999AspAsp: 3.999 ± 0.044	4.567AspGlu: 4.567 ± 0.043	1.753AspPhe: 1.753 ± 0.025	4.249AspGly: 4.249 ± 0.04	1.193AspHis: 1.193 ± 0.018	1.952AspIle: 1.952 ± 0.023	1.936AspLys: 1.936 ± 0.024	4.954AspLeu: 4.954 ± 0.039	0.953AspMet: 0.953 ± 0.013	1.275AspAsn: 1.275 ± 0.021	2.96AspPro: 2.96 ± 0.031	1.928AspGln: 1.928 ± 0.022	3.099AspArg: 3.099 ± 0.03	4.076AspSer: 4.076 ± 0.034	2.474AspThr: 2.474 ± 0.026	3.856AspVal: 3.856 ± 0.034	0.786AspTrp: 0.786 ± 0.013	1.098AspTyr: 1.098 ± 0.016	0.002AspXaa: 0.002 ± 0.001
Glu	6.83GluAla: 6.83 ± 0.053	0.504GluCys: 0.504 ± 0.013	3.846GluAsp: 3.846 ± 0.04	5.544GluGlu: 5.544 ± 0.058	1.241GluPhe: 1.241 ± 0.019	4.034GluGly: 4.034 ± 0.037	1.563GluHis: 1.563 ± 0.022	2.056GluIle: 2.056 ± 0.023	2.77GluLys: 2.77 ± 0.034	5.165GluLeu: 5.165 ± 0.047	1.318GluMet: 1.318 ± 0.021	1.488GluAsn: 1.488 ± 0.023	2.472GluPro: 2.472 ± 0.025	2.84GluGln: 2.84 ± 0.033	4.681GluArg: 4.681 ± 0.044	4.315GluSer: 4.315 ± 0.034	2.757GluThr: 2.757 ± 0.025	3.343GluVal: 3.343 ± 0.031	0.789GluTrp: 0.789 ± 0.015	1.141GluTyr: 1.141 ± 0.02	0.002GluXaa: 0.002 ± 0.001
Phe	3.34PheAla: 3.34 ± 0.035	0.4PheCys: 0.4 ± 0.012	1.971PheAsp: 1.971 ± 0.025	1.865PheGlu: 1.865 ± 0.024	1.186PhePhe: 1.186 ± 0.019	2.629PheGly: 2.629 ± 0.034	0.685PheHis: 0.685 ± 0.014	1.19PheIle: 1.19 ± 0.02	1.237PheLys: 1.237 ± 0.019	2.645PheLeu: 2.645 ± 0.032	0.548PheMet: 0.548 ± 0.012	1.009PheAsn: 1.009 ± 0.017	1.461PhePro: 1.461 ± 0.021	1.005PheGln: 1.005 ± 0.015	1.645PheArg: 1.645 ± 0.023	2.57PheSer: 2.57 ± 0.028	1.566PheThr: 1.566 ± 0.021	2.079PheVal: 2.079 ± 0.023	0.45PheTrp: 0.45 ± 0.012	0.736PheTyr: 0.736 ± 0.014	0.001PheXaa: 0.001 ± 0.0
Gly	8.145GlyAla: 8.145 ± 0.057	0.682GlyCys: 0.682 ± 0.016	3.623GlyAsp: 3.623 ± 0.03	3.775GlyGlu: 3.775 ± 0.035	2.259GlyPhe: 2.259 ± 0.028	6.731GlyGly: 6.731 ± 0.075	1.877GlyHis: 1.877 ± 0.024	2.82GlyIle: 2.82 ± 0.03	3.421GlyLys: 3.421 ± 0.031	6.152GlyLeu: 6.152 ± 0.04	1.442GlyMet: 1.442 ± 0.023	2.25GlyAsn: 2.25 ± 0.027	3.933GlyPro: 3.933 ± 0.038	2.965GlyGln: 2.965 ± 0.031	4.74GlyArg: 4.74 ± 0.043	7.316GlySer: 7.316 ± 0.062	4.226GlyThr: 4.226 ± 0.034	4.162GlyVal: 4.162 ± 0.035	1.059GlyTrp: 1.059 ± 0.017	1.613GlyTyr: 1.613 ± 0.027	0.004GlyXaa: 0.004 ± 0.001
His	2.915HisAla: 2.915 ± 0.028	0.279HisCys: 0.279 ± 0.009	1.316HisAsp: 1.316 ± 0.019	1.323HisGlu: 1.323 ± 0.021	0.881HisPhe: 0.881 ± 0.017	1.801HisGly: 1.801 ± 0.026	0.944HisHis: 0.944 ± 0.02	1.02HisIle: 1.02 ± 0.014	0.886HisLys: 0.886 ± 0.017	2.586HisLeu: 2.586 ± 0.029	0.438HisMet: 0.438 ± 0.011	0.703HisAsn: 0.703 ± 0.014	1.692HisPro: 1.692 ± 0.025	1.07HisGln: 1.07 ± 0.015	1.73HisArg: 1.73 ± 0.023	2.318HisSer: 2.318 ± 0.027	1.349HisThr: 1.349 ± 0.02	1.571HisVal: 1.571 ± 0.022	0.311HisTrp: 0.311 ± 0.008	0.559HisTyr: 0.559 ± 0.014	0.001HisXaa: 0.001 ± 0.0
Ile	4.098IleAla: 4.098 ± 0.034	0.531IleCys: 0.531 ± 0.013	2.32IleAsp: 2.32 ± 0.027	2.268IleGlu: 2.268 ± 0.027	1.405IlePhe: 1.405 ± 0.018	2.689IleGly: 2.689 ± 0.031	0.903IleHis: 0.903 ± 0.016	1.62IleIle: 1.62 ± 0.022	1.682IleLys: 1.682 ± 0.021	3.399IleLeu: 3.399 ± 0.035	0.662IleMet: 0.662 ± 0.014	1.222IleAsn: 1.222 ± 0.018	2.104IlePro: 2.104 ± 0.021	1.321IleGln: 1.321 ± 0.02	2.341IleArg: 2.341 ± 0.026	3.299IleSer: 3.299 ± 0.028	1.979IleThr: 1.979 ± 0.024	2.544IleVal: 2.544 ± 0.029	0.531IleTrp: 0.531 ± 0.012	0.858IleTyr: 0.858 ± 0.016	0.001IleXaa: 0.001 ± 0.001
Lys	4.698LysAla: 4.698 ± 0.042	0.365LysCys: 0.365 ± 0.009	2.375LysAsp: 2.375 ± 0.029	2.918LysGlu: 2.918 ± 0.033	0.965LysPhe: 0.965 ± 0.017	3.054LysGly: 3.054 ± 0.031	1.09LysHis: 1.09 ± 0.016	1.464LysIle: 1.464 ± 0.018	2.455LysLys: 2.455 ± 0.038	3.567LysLeu: 3.567 ± 0.035	0.806LysMet: 0.806 ± 0.015	1.124LysAsn: 1.124 ± 0.02	2.229LysPro: 2.229 ± 0.025	1.759LysGln: 1.759 ± 0.022	3.67LysArg: 3.67 ± 0.031	3.362LysSer: 3.362 ± 0.031	2.245LysThr: 2.245 ± 0.027	2.447LysVal: 2.447 ± 0.028	0.521LysTrp: 0.521 ± 0.012	0.881LysTyr: 0.881 ± 0.015	0.001LysXaa: 0.001 ± 0.001
Leu	9.665LeuAla: 9.665 ± 0.063	1.133LeuCys: 1.133 ± 0.018	5.272LeuAsp: 5.272 ± 0.043	5.141LeuGlu: 5.141 ± 0.047	2.815LeuPhe: 2.815 ± 0.035	6.17LeuGly: 6.17 ± 0.045	2.41LeuHis: 2.41 ± 0.028	3.354LeuIle: 3.354 ± 0.031	3.576LeuLys: 3.576 ± 0.033	8.741LeuLeu: 8.741 ± 0.085	1.463LeuMet: 1.463 ± 0.019	2.649LeuAsn: 2.649 ± 0.026	6.011LeuPro: 6.011 ± 0.044	3.93LeuGln: 3.93 ± 0.033	6.51LeuArg: 6.51 ± 0.053	8.119LeuSer: 8.119 ± 0.067	4.488LeuThr: 4.488 ± 0.036	5.166LeuVal: 5.166 ± 0.043	1.028LeuTrp: 1.028 ± 0.018	1.872LeuTyr: 1.872 ± 0.027	0.002LeuXaa: 0.002 ± 0.001
Met	1.845MetAla: 1.845 ± 0.02	0.198MetCys: 0.198 ± 0.006	1.034MetAsp: 1.034 ± 0.015	0.969MetGlu: 0.969 ± 0.018	0.462MetPhe: 0.462 ± 0.011	1.27MetGly: 1.27 ± 0.021	0.498MetHis: 0.498 ± 0.011	0.67MetIle: 0.67 ± 0.015	0.66MetLys: 0.66 ± 0.013	1.778MetLeu: 1.778 ± 0.024	0.407MetMet: 0.407 ± 0.011	0.501MetAsn: 0.501 ± 0.01	1.222MetPro: 1.222 ± 0.018	0.845MetGln: 0.845 ± 0.015	1.419MetArg: 1.419 ± 0.018	1.959MetSer: 1.959 ± 0.022	1.085MetThr: 1.085 ± 0.017	0.933MetVal: 0.933 ± 0.016	0.215MetTrp: 0.215 ± 0.007	0.374MetTyr: 0.374 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.72AsnAla: 3.72 ± 0.035	0.268AsnCys: 0.268 ± 0.008	1.537AsnAsp: 1.537 ± 0.022	1.676AsnGlu: 1.676 ± 0.022	0.959AsnPhe: 0.959 ± 0.017	2.624AsnGly: 2.624 ± 0.03	0.636AsnHis: 0.636 ± 0.013	1.218AsnIle: 1.218 ± 0.019	1.206AsnLys: 1.206 ± 0.018	2.615AsnLeu: 2.615 ± 0.03	0.538AsnMet: 0.538 ± 0.011	0.971AsnAsn: 0.971 ± 0.022	1.76AsnPro: 1.76 ± 0.022	1.006AsnGln: 1.006 ± 0.019	1.704AsnArg: 1.704 ± 0.023	2.353AsnSer: 2.353 ± 0.026	1.678AsnThr: 1.678 ± 0.021	2.136AsnVal: 2.136 ± 0.026	0.365AsnTrp: 0.365 ± 0.009	0.593AsnTyr: 0.593 ± 0.013	0.001AsnXaa: 0.001 ± 0.001
Pro	6.789ProAla: 6.789 ± 0.061	0.477ProCys: 0.477 ± 0.012	2.823ProAsp: 2.823 ± 0.028	2.976ProGlu: 2.976 ± 0.028	1.899ProPhe: 1.899 ± 0.021	4.021ProGly: 4.021 ± 0.041	1.613ProHis: 1.613 ± 0.021	2.191ProIle: 2.191 ± 0.022	2.228ProLys: 2.228 ± 0.027	5.226ProLeu: 5.226 ± 0.042	0.937ProMet: 0.937 ± 0.016	1.89ProAsn: 1.89 ± 0.025	5.224ProPro: 5.224 ± 0.069	2.402ProGln: 2.402 ± 0.034	3.999ProArg: 3.999 ± 0.041	7.546ProSer: 7.546 ± 0.067	4.012ProThr: 4.012 ± 0.039	3.141ProVal: 3.141 ± 0.03	0.634ProTrp: 0.634 ± 0.013	1.173ProTyr: 1.173 ± 0.018	0.003ProXaa: 0.003 ± 0.001
Gln	4.883GlnAla: 4.883 ± 0.045	0.351GlnCys: 0.351 ± 0.009	2.147GlnAsp: 2.147 ± 0.024	2.454GlnGlu: 2.454 ± 0.027	0.888GlnPhe: 0.888 ± 0.017	2.936GlnGly: 2.936 ± 0.034	1.338GlnHis: 1.338 ± 0.018	1.531GlnIle: 1.531 ± 0.019	1.58GlnLys: 1.58 ± 0.021	3.607GlnLeu: 3.607 ± 0.032	0.81GlnMet: 0.81 ± 0.017	1.192GlnAsn: 1.192 ± 0.019	2.469GlnPro: 2.469 ± 0.031	2.744GlnGln: 2.744 ± 0.053	3.409GlnArg: 3.409 ± 0.033	3.747GlnSer: 3.747 ± 0.038	2.293GlnThr: 2.293 ± 0.022	2.257GlnVal: 2.257 ± 0.023	0.471GlnTrp: 0.471 ± 0.01	0.815GlnTyr: 0.815 ± 0.017	0.001GlnXaa: 0.001 ± 0.0
Arg	7.363ArgAla: 7.363 ± 0.048	0.692ArgCys: 0.692 ± 0.014	3.513ArgAsp: 3.513 ± 0.033	4.057ArgGlu: 4.057 ± 0.043	2.058ArgPhe: 2.058 ± 0.024	4.609ArgGly: 4.609 ± 0.046	1.781ArgHis: 1.781 ± 0.026	2.761ArgIle: 2.761 ± 0.026	3.355ArgLys: 3.355 ± 0.035	6.184ArgLeu: 6.184 ± 0.051	1.389ArgMet: 1.389 ± 0.02	2.132ArgAsn: 2.132 ± 0.022	4.191ArgPro: 4.191 ± 0.044	2.973ArgGln: 2.973 ± 0.028	6.286ArgArg: 6.286 ± 0.058	6.747ArgSer: 6.747 ± 0.062	3.722ArgThr: 3.722 ± 0.037	3.563ArgVal: 3.563 ± 0.032	0.933ArgTrp: 0.933 ± 0.015	1.388ArgTyr: 1.388 ± 0.022	0.002ArgXaa: 0.002 ± 0.001
Ser	11.386SerAla: 11.386 ± 0.075	0.779SerCys: 0.779 ± 0.018	4.708SerAsp: 4.708 ± 0.039	4.492SerGlu: 4.492 ± 0.034	2.833SerPhe: 2.833 ± 0.028	7.142SerGly: 7.142 ± 0.053	2.34SerHis: 2.34 ± 0.03	3.649SerIle: 3.649 ± 0.033	3.88SerLys: 3.88 ± 0.036	7.953SerLeu: 7.953 ± 0.067	1.702SerMet: 1.702 ± 0.022	3.12SerAsn: 3.12 ± 0.033	6.387SerPro: 6.387 ± 0.077	3.735SerGln: 3.735 ± 0.039	6.53SerArg: 6.53 ± 0.054	13.11SerSer: 13.11 ± 0.116	6.719SerThr: 6.719 ± 0.055	4.913SerVal: 4.913 ± 0.046	1.014SerTrp: 1.014 ± 0.017	1.689SerTyr: 1.689 ± 0.022	0.004SerXaa: 0.004 ± 0.001
Thr	5.899ThrAla: 5.899 ± 0.041	0.619ThrCys: 0.619 ± 0.014	2.563ThrAsp: 2.563 ± 0.024	2.496ThrGlu: 2.496 ± 0.028	1.938ThrPhe: 1.938 ± 0.023	3.95ThrGly: 3.95 ± 0.034	1.372ThrHis: 1.372 ± 0.02	2.175ThrIle: 2.175 ± 0.024	2.037ThrLys: 2.037 ± 0.024	5.295ThrLeu: 5.295 ± 0.043	0.958ThrMet: 0.958 ± 0.016	1.645ThrAsn: 1.645 ± 0.024	4.258ThrPro: 4.258 ± 0.043	2.061ThrGln: 2.061 ± 0.024	3.523ThrArg: 3.523 ± 0.028	6.73ThrSer: 6.73 ± 0.057	3.576ThrThr: 3.576 ± 0.041	2.871ThrVal: 2.871 ± 0.031	0.694ThrTrp: 0.694 ± 0.013	1.163ThrTyr: 1.163 ± 0.02	0.001ThrXaa: 0.001 ± 0.0
Val	5.913ValAla: 5.913 ± 0.043	0.661ValCys: 0.661 ± 0.015	3.554ValAsp: 3.554 ± 0.03	3.629ValGlu: 3.629 ± 0.03	1.788ValPhe: 1.788 ± 0.024	4.085ValGly: 4.085 ± 0.033	1.479ValHis: 1.479 ± 0.022	2.259ValIle: 2.259 ± 0.028	2.505ValLys: 2.505 ± 0.028	5.37ValLeu: 5.37 ± 0.05	1.013ValMet: 1.013 ± 0.016	1.639ValAsn: 1.639 ± 0.023	3.609ValPro: 3.609 ± 0.029	2.455ValGln: 2.455 ± 0.027	3.869ValArg: 3.869 ± 0.035	4.553ValSer: 4.553 ± 0.041	2.889ValThr: 2.889 ± 0.032	3.714ValVal: 3.714 ± 0.036	0.781ValTrp: 0.781 ± 0.013	1.252ValTyr: 1.252 ± 0.019	0.001ValXaa: 0.001 ± 0.0
Trp	1.152TrpAla: 1.152 ± 0.018	0.161TrpCys: 0.161 ± 0.006	0.74TrpAsp: 0.74 ± 0.015	0.657TrpGlu: 0.657 ± 0.012	0.385TrpPhe: 0.385 ± 0.011	0.764TrpGly: 0.764 ± 0.015	0.35TrpHis: 0.35 ± 0.01	0.576TrpIle: 0.576 ± 0.013	0.599TrpLys: 0.599 ± 0.013	1.221TrpLeu: 1.221 ± 0.016	0.279TrpMet: 0.279 ± 0.008	0.49TrpAsn: 0.49 ± 0.011	0.571TrpPro: 0.571 ± 0.014	0.599TrpGln: 0.599 ± 0.012	0.956TrpArg: 0.956 ± 0.017	1.141TrpSer: 1.141 ± 0.018	0.808TrpThr: 0.808 ± 0.016	0.643TrpVal: 0.643 ± 0.016	0.223TrpTrp: 0.223 ± 0.007	0.295TrpTyr: 0.295 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.169TyrAla: 2.169 ± 0.025	0.276TyrCys: 0.276 ± 0.008	1.253TyrAsp: 1.253 ± 0.02	1.183TyrGlu: 1.183 ± 0.019	0.79TyrPhe: 0.79 ± 0.014	1.67TyrGly: 1.67 ± 0.028	0.543TyrHis: 0.543 ± 0.012	0.836TyrIle: 0.836 ± 0.016	0.812TyrLys: 0.812 ± 0.017	1.912TyrLeu: 1.912 ± 0.027	0.39TyrMet: 0.39 ± 0.011	0.694TyrAsn: 0.694 ± 0.015	1.039TyrPro: 1.039 ± 0.015	0.745TyrGln: 0.745 ± 0.015	1.287TyrArg: 1.287 ± 0.017	1.569TyrSer: 1.569 ± 0.023	1.13TyrThr: 1.13 ± 0.02	1.289TyrVal: 1.289 ± 0.02	0.294TyrTrp: 0.294 ± 0.009	0.565TyrTyr: 0.565 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.002XaaAla: 0.002 ± 0.001	0.001XaaCys: 0.001 ± 0.0	0.001XaaAsp: 0.001 ± 0.001	0.002XaaGlu: 0.002 ± 0.001	0.001XaaPhe: 0.001 ± 0.001	0.001XaaGly: 0.001 ± 0.001	0.0XaaHis: 0.0 ± 0.0	0.001XaaIle: 0.001 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.005XaaLeu: 0.005 ± 0.001	0.005XaaMet: 0.005 ± 0.001	0.001XaaAsn: 0.001 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.001XaaGln: 0.001 ± 0.0	0.003XaaArg: 0.003 ± 0.001	0.002XaaSer: 0.002 ± 0.001	0.001XaaThr: 0.001 ± 0.0	0.002XaaVal: 0.002 ± 0.001	0.001XaaTrp: 0.001 ± 0.0	0.001XaaTyr: 0.001 ± 0.0	0.071XaaXaa: 0.071 ± 0.007

Statistics based on 8017 proteins (3982424 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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