Amino acid dipepetide frequency for Leifsonia xyli

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	20.398AlaAla: 20.398 ± 0.207	0.651AlaCys: 0.651 ± 0.027	7.973AlaAsp: 7.973 ± 0.1	7.867AlaGlu: 7.867 ± 0.132	4.161AlaPhe: 4.161 ± 0.074	12.322AlaGly: 12.322 ± 0.117	2.313AlaHis: 2.313 ± 0.048	5.796AlaIle: 5.796 ± 0.09	2.936AlaLys: 2.936 ± 0.078	13.995AlaLeu: 13.995 ± 0.156	2.553AlaMet: 2.553 ± 0.048	2.477AlaAsn: 2.477 ± 0.053	6.475AlaPro: 6.475 ± 0.104	3.928AlaGln: 3.928 ± 0.07	8.782AlaArg: 8.782 ± 0.106	7.346AlaSer: 7.346 ± 0.093	7.502AlaThr: 7.502 ± 0.109	12.043AlaVal: 12.043 ± 0.125	1.82AlaTrp: 1.82 ± 0.045	2.497AlaTyr: 2.497 ± 0.055	0.0AlaXaa: 0.0 ± 0.0
Cys	0.57CysAla: 0.57 ± 0.026	0.039CysCys: 0.039 ± 0.006	0.293CysAsp: 0.293 ± 0.018	0.209CysGlu: 0.209 ± 0.014	0.189CysPhe: 0.189 ± 0.015	0.54CysGly: 0.54 ± 0.022	0.101CysHis: 0.101 ± 0.011	0.188CysIle: 0.188 ± 0.014	0.061CysLys: 0.061 ± 0.008	0.439CysLeu: 0.439 ± 0.021	0.074CysMet: 0.074 ± 0.009	0.094CysAsn: 0.094 ± 0.009	0.279CysPro: 0.279 ± 0.018	0.11CysGln: 0.11 ± 0.011	0.273CysArg: 0.273 ± 0.017	0.349CysSer: 0.349 ± 0.022	0.307CysThr: 0.307 ± 0.02	0.42CysVal: 0.42 ± 0.022	0.075CysTrp: 0.075 ± 0.008	0.08CysTyr: 0.08 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	8.869AspAla: 8.869 ± 0.104	0.232AspCys: 0.232 ± 0.014	4.158AspAsp: 4.158 ± 0.08	4.162AspGlu: 4.162 ± 0.077	1.746AspPhe: 1.746 ± 0.033	6.221AspGly: 6.221 ± 0.09	1.144AspHis: 1.144 ± 0.033	2.289AspIle: 2.289 ± 0.057	1.099AspLys: 1.099 ± 0.042	6.091AspLeu: 6.091 ± 0.087	0.708AspMet: 0.708 ± 0.028	0.998AspAsn: 0.998 ± 0.04	4.192AspPro: 4.192 ± 0.079	1.644AspGln: 1.644 ± 0.044	4.617AspArg: 4.617 ± 0.077	2.645AspSer: 2.645 ± 0.058	2.977AspThr: 2.977 ± 0.064	5.106AspVal: 5.106 ± 0.07	0.996AspTrp: 0.996 ± 0.03	1.275AspTyr: 1.275 ± 0.037	0.0AspXaa: 0.0 ± 0.0
Glu	7.0GluAla: 7.0 ± 0.121	0.192GluCys: 0.192 ± 0.013	2.683GluAsp: 2.683 ± 0.068	3.128GluGlu: 3.128 ± 0.064	1.655GluPhe: 1.655 ± 0.046	3.815GluGly: 3.815 ± 0.068	1.335GluHis: 1.335 ± 0.045	2.328GluIle: 2.328 ± 0.058	1.452GluLys: 1.452 ± 0.042	6.764GluLeu: 6.764 ± 0.112	0.785GluMet: 0.785 ± 0.028	1.156GluAsn: 1.156 ± 0.035	3.114GluPro: 3.114 ± 0.071	2.247GluGln: 2.247 ± 0.06	5.296GluArg: 5.296 ± 0.095	2.713GluSer: 2.713 ± 0.052	3.003GluThr: 3.003 ± 0.065	4.324GluVal: 4.324 ± 0.083	0.826GluTrp: 0.826 ± 0.032	1.12GluTyr: 1.12 ± 0.033	0.0GluXaa: 0.0 ± 0.0
Phe	4.377PheAla: 4.377 ± 0.077	0.172PheCys: 0.172 ± 0.014	2.363PheAsp: 2.363 ± 0.052	1.787PheGlu: 1.787 ± 0.047	1.181PhePhe: 1.181 ± 0.043	3.475PheGly: 3.475 ± 0.061	0.554PheHis: 0.554 ± 0.022	1.225PheIle: 1.225 ± 0.042	0.493PheLys: 0.493 ± 0.022	2.943PheLeu: 2.943 ± 0.057	0.396PheMet: 0.396 ± 0.02	0.666PheAsn: 0.666 ± 0.026	1.515PhePro: 1.515 ± 0.041	0.807PheGln: 0.807 ± 0.028	1.935PheArg: 1.935 ± 0.049	1.816PheSer: 1.816 ± 0.051	2.135PheThr: 2.135 ± 0.05	3.016PheVal: 3.016 ± 0.062	0.532PheTrp: 0.532 ± 0.023	0.733PheTyr: 0.733 ± 0.026	0.0PheXaa: 0.0 ± 0.0
Gly	10.588GlyAla: 10.588 ± 0.115	0.541GlyCys: 0.541 ± 0.026	5.162GlyAsp: 5.162 ± 0.074	4.719GlyGlu: 4.719 ± 0.075	3.37GlyPhe: 3.37 ± 0.074	7.784GlyGly: 7.784 ± 0.133	1.806GlyHis: 1.806 ± 0.047	4.596GlyIle: 4.596 ± 0.077	2.227GlyLys: 2.227 ± 0.055	8.752GlyLeu: 8.752 ± 0.106	1.954GlyMet: 1.954 ± 0.043	1.784GlyAsn: 1.784 ± 0.049	3.881GlyPro: 3.881 ± 0.063	2.526GlyGln: 2.526 ± 0.064	6.574GlyArg: 6.574 ± 0.083	5.603GlySer: 5.603 ± 0.092	5.662GlyThr: 5.662 ± 0.087	7.987GlyVal: 7.987 ± 0.112	1.799GlyTrp: 1.799 ± 0.047	2.357GlyTyr: 2.357 ± 0.053	0.0GlyXaa: 0.0 ± 0.0
His	2.247HisAla: 2.247 ± 0.056	0.105HisCys: 0.105 ± 0.01	1.269HisAsp: 1.269 ± 0.034	1.11HisGlu: 1.11 ± 0.037	0.564HisPhe: 0.564 ± 0.025	1.84HisGly: 1.84 ± 0.043	0.511HisHis: 0.511 ± 0.027	0.75HisIle: 0.75 ± 0.026	0.3HisLys: 0.3 ± 0.018	1.961HisLeu: 1.961 ± 0.052	0.261HisMet: 0.261 ± 0.016	0.345HisAsn: 0.345 ± 0.018	1.595HisPro: 1.595 ± 0.043	0.47HisGln: 0.47 ± 0.023	1.489HisArg: 1.489 ± 0.043	0.98HisSer: 0.98 ± 0.035	0.995HisThr: 0.995 ± 0.032	1.578HisVal: 1.578 ± 0.043	0.291HisTrp: 0.291 ± 0.019	0.464HisTyr: 0.464 ± 0.02	0.0HisXaa: 0.0 ± 0.0
Ile	6.68IleAla: 6.68 ± 0.087	0.205IleCys: 0.205 ± 0.015	3.048IleAsp: 3.048 ± 0.061	2.634IleGlu: 2.634 ± 0.05	1.186IlePhe: 1.186 ± 0.043	4.617IleGly: 4.617 ± 0.084	0.805IleHis: 0.805 ± 0.03	1.745IleIle: 1.745 ± 0.056	0.833IleLys: 0.833 ± 0.031	3.95IleLeu: 3.95 ± 0.086	0.563IleMet: 0.563 ± 0.024	0.921IleAsn: 0.921 ± 0.032	2.478IlePro: 2.478 ± 0.058	1.158IleGln: 1.158 ± 0.036	2.696IleArg: 2.696 ± 0.062	2.153IleSer: 2.153 ± 0.052	2.638IleThr: 2.638 ± 0.061	4.826IleVal: 4.826 ± 0.082	0.481IleTrp: 0.481 ± 0.025	0.763IleTyr: 0.763 ± 0.029	0.0IleXaa: 0.0 ± 0.0
Lys	2.778LysAla: 2.778 ± 0.069	0.08LysCys: 0.08 ± 0.009	1.255LysAsp: 1.255 ± 0.045	1.028LysGlu: 1.028 ± 0.037	0.54LysPhe: 0.54 ± 0.024	1.631LysGly: 1.631 ± 0.051	0.488LysHis: 0.488 ± 0.023	0.917LysIle: 0.917 ± 0.038	0.842LysLys: 0.842 ± 0.041	2.065LysLeu: 2.065 ± 0.045	0.38LysMet: 0.38 ± 0.018	0.641LysAsn: 0.641 ± 0.031	1.373LysPro: 1.373 ± 0.043	0.792LysGln: 0.792 ± 0.029	1.679LysArg: 1.679 ± 0.045	1.194LysSer: 1.194 ± 0.041	1.41LysThr: 1.41 ± 0.039	1.831LysVal: 1.831 ± 0.052	0.257LysTrp: 0.257 ± 0.017	0.493LysTyr: 0.493 ± 0.024	0.0LysXaa: 0.0 ± 0.0
Leu	14.503LeuAla: 14.503 ± 0.139	0.504LeuCys: 0.504 ± 0.022	6.651LeuAsp: 6.651 ± 0.1	4.859LeuGlu: 4.859 ± 0.1	3.102LeuPhe: 3.102 ± 0.068	9.2LeuGly: 9.2 ± 0.111	1.941LeuHis: 1.941 ± 0.046	4.554LeuIle: 4.554 ± 0.094	1.974LeuLys: 1.974 ± 0.054	10.511LeuLeu: 10.511 ± 0.148	1.54LeuMet: 1.54 ± 0.039	1.947LeuAsn: 1.947 ± 0.051	5.672LeuPro: 5.672 ± 0.078	2.696LeuGln: 2.696 ± 0.05	7.333LeuArg: 7.333 ± 0.115	5.862LeuSer: 5.862 ± 0.08	6.579LeuThr: 6.579 ± 0.081	9.102LeuVal: 9.102 ± 0.112	1.362LeuTrp: 1.362 ± 0.041	1.829LeuTyr: 1.829 ± 0.042	0.0LeuXaa: 0.0 ± 0.0
Met	1.96MetAla: 1.96 ± 0.044	0.079MetCys: 0.079 ± 0.009	0.826MetAsp: 0.826 ± 0.027	0.638MetGlu: 0.638 ± 0.027	0.496MetPhe: 0.496 ± 0.022	1.187MetGly: 1.187 ± 0.037	0.308MetHis: 0.308 ± 0.016	0.797MetIle: 0.797 ± 0.032	0.424MetLys: 0.424 ± 0.022	1.775MetLeu: 1.775 ± 0.043	0.255MetMet: 0.255 ± 0.018	0.449MetAsn: 0.449 ± 0.022	0.999MetPro: 0.999 ± 0.036	0.477MetGln: 0.477 ± 0.022	1.348MetArg: 1.348 ± 0.043	1.325MetSer: 1.325 ± 0.035	1.678MetThr: 1.678 ± 0.038	1.291MetVal: 1.291 ± 0.036	0.197MetTrp: 0.197 ± 0.013	0.245MetTyr: 0.245 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	2.735AsnAla: 2.735 ± 0.061	0.115AsnCys: 0.115 ± 0.012	1.206AsnAsp: 1.206 ± 0.037	0.964AsnGlu: 0.964 ± 0.033	0.641AsnPhe: 0.641 ± 0.026	2.184AsnGly: 2.184 ± 0.055	0.371AsnHis: 0.371 ± 0.02	0.875AsnIle: 0.875 ± 0.036	0.462AsnLys: 0.462 ± 0.022	1.89AsnLeu: 1.89 ± 0.045	0.288AsnMet: 0.288 ± 0.02	0.523AsnAsn: 0.523 ± 0.024	1.623AsnPro: 1.623 ± 0.04	0.622AsnGln: 0.622 ± 0.03	1.399AsnArg: 1.399 ± 0.043	1.035AsnSer: 1.035 ± 0.038	1.189AsnThr: 1.189 ± 0.039	1.702AsnVal: 1.702 ± 0.044	0.319AsnTrp: 0.319 ± 0.017	0.504AsnTyr: 0.504 ± 0.022	0.0AsnXaa: 0.0 ± 0.0
Pro	7.509ProAla: 7.509 ± 0.109	0.168ProCys: 0.168 ± 0.012	3.882ProAsp: 3.882 ± 0.07	3.797ProGlu: 3.797 ± 0.068	1.826ProPhe: 1.826 ± 0.038	5.072ProGly: 5.072 ± 0.077	1.048ProHis: 1.048 ± 0.033	2.152ProIle: 2.152 ± 0.053	1.226ProLys: 1.226 ± 0.039	5.03ProLeu: 5.03 ± 0.073	0.813ProMet: 0.813 ± 0.031	1.192ProAsn: 1.192 ± 0.033	2.383ProPro: 2.383 ± 0.057	1.664ProGln: 1.664 ± 0.043	3.213ProArg: 3.213 ± 0.073	3.405ProSer: 3.405 ± 0.063	3.444ProThr: 3.444 ± 0.072	5.027ProVal: 5.027 ± 0.075	0.86ProTrp: 0.86 ± 0.03	1.11ProTyr: 1.11 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	3.584GlnAla: 3.584 ± 0.064	0.113GlnCys: 0.113 ± 0.011	1.317GlnAsp: 1.317 ± 0.039	1.385GlnGlu: 1.385 ± 0.04	0.842GlnPhe: 0.842 ± 0.026	2.118GlnGly: 2.118 ± 0.047	0.671GlnHis: 0.671 ± 0.024	1.269GlnIle: 1.269 ± 0.039	0.811GlnLys: 0.811 ± 0.03	3.516GlnLeu: 3.516 ± 0.064	0.408GlnMet: 0.408 ± 0.02	0.795GlnAsn: 0.795 ± 0.03	1.684GlnPro: 1.684 ± 0.045	1.321GlnGln: 1.321 ± 0.041	2.409GlnArg: 2.409 ± 0.059	1.54GlnSer: 1.54 ± 0.043	1.679GlnThr: 1.679 ± 0.043	2.426GlnVal: 2.426 ± 0.054	0.453GlnTrp: 0.453 ± 0.019	0.7GlnTyr: 0.7 ± 0.027	0.0GlnXaa: 0.0 ± 0.0
Arg	8.439ArgAla: 8.439 ± 0.1	0.292ArgCys: 0.292 ± 0.019	4.282ArgAsp: 4.282 ± 0.085	4.37ArgGlu: 4.37 ± 0.084	2.472ArgPhe: 2.472 ± 0.05	5.201ArgGly: 5.201 ± 0.087	1.439ArgHis: 1.439 ± 0.044	3.765ArgIle: 3.765 ± 0.065	1.48ArgLys: 1.48 ± 0.047	7.293ArgLeu: 7.293 ± 0.107	1.757ArgMet: 1.757 ± 0.04	1.398ArgAsn: 1.398 ± 0.041	3.891ArgPro: 3.891 ± 0.068	2.026ArgGln: 2.026 ± 0.049	6.504ArgArg: 6.504 ± 0.111	4.118ArgSer: 4.118 ± 0.074	4.315ArgThr: 4.315 ± 0.07	5.916ArgVal: 5.916 ± 0.083	1.18ArgTrp: 1.18 ± 0.038	1.649ArgTyr: 1.649 ± 0.042	0.0ArgXaa: 0.0 ± 0.0
Ser	7.135SerAla: 7.135 ± 0.101	0.251SerCys: 0.251 ± 0.017	3.319SerAsp: 3.319 ± 0.066	2.692SerGlu: 2.692 ± 0.06	1.851SerPhe: 1.851 ± 0.045	5.985SerGly: 5.985 ± 0.092	0.992SerHis: 0.992 ± 0.03	2.556SerIle: 2.556 ± 0.055	1.205SerLys: 1.205 ± 0.043	5.36SerLeu: 5.36 ± 0.08	1.065SerMet: 1.065 ± 0.03	1.187SerAsn: 1.187 ± 0.037	3.141SerPro: 3.141 ± 0.058	1.487SerGln: 1.487 ± 0.043	3.819SerArg: 3.819 ± 0.063	3.545SerSer: 3.545 ± 0.071	3.749SerThr: 3.749 ± 0.073	4.783SerVal: 4.783 ± 0.079	0.974SerTrp: 0.974 ± 0.026	1.286SerTyr: 1.286 ± 0.031	0.0SerXaa: 0.0 ± 0.0
Thr	8.245ThrAla: 8.245 ± 0.11	0.263ThrCys: 0.263 ± 0.015	3.577ThrAsp: 3.577 ± 0.066	2.99ThrGlu: 2.99 ± 0.056	1.927ThrPhe: 1.927 ± 0.049	6.04ThrGly: 6.04 ± 0.091	1.08ThrHis: 1.08 ± 0.033	2.952ThrIle: 2.952 ± 0.052	1.331ThrLys: 1.331 ± 0.044	5.927ThrLeu: 5.927 ± 0.08	0.951ThrMet: 0.951 ± 0.032	1.229ThrAsn: 1.229 ± 0.037	3.976ThrPro: 3.976 ± 0.066	1.563ThrGln: 1.563 ± 0.047	3.679ThrArg: 3.679 ± 0.062	3.454ThrSer: 3.454 ± 0.061	3.969ThrThr: 3.969 ± 0.086	6.213ThrVal: 6.213 ± 0.081	0.86ThrTrp: 0.86 ± 0.031	1.246ThrTyr: 1.246 ± 0.04	0.0ThrXaa: 0.0 ± 0.0
Val	12.071ValAla: 12.071 ± 0.118	0.478ValCys: 0.478 ± 0.024	5.693ValAsp: 5.693 ± 0.087	4.8ValGlu: 4.8 ± 0.082	3.005ValPhe: 3.005 ± 0.069	7.333ValGly: 7.333 ± 0.093	1.576ValHis: 1.576 ± 0.038	4.206ValIle: 4.206 ± 0.08	1.796ValLys: 1.796 ± 0.054	9.316ValLeu: 9.316 ± 0.116	1.386ValMet: 1.386 ± 0.038	1.895ValAsn: 1.895 ± 0.055	4.704ValPro: 4.704 ± 0.077	2.305ValGln: 2.305 ± 0.049	5.854ValArg: 5.854 ± 0.079	5.153ValSer: 5.153 ± 0.071	5.976ValThr: 5.976 ± 0.086	9.215ValVal: 9.215 ± 0.123	1.165ValTrp: 1.165 ± 0.03	1.71ValTyr: 1.71 ± 0.043	0.0ValXaa: 0.0 ± 0.0
Trp	1.582TrpAla: 1.582 ± 0.044	0.091TrpCys: 0.091 ± 0.01	0.776TrpAsp: 0.776 ± 0.029	0.649TrpGlu: 0.649 ± 0.027	0.591TrpPhe: 0.591 ± 0.029	1.102TrpGly: 1.102 ± 0.035	0.307TrpHis: 0.307 ± 0.019	0.691TrpIle: 0.691 ± 0.028	0.346TrpLys: 0.346 ± 0.02	1.852TrpLeu: 1.852 ± 0.046	0.355TrpMet: 0.355 ± 0.018	0.459TrpAsn: 0.459 ± 0.021	0.741TrpPro: 0.741 ± 0.029	0.542TrpGln: 0.542 ± 0.021	1.241TrpArg: 1.241 ± 0.041	0.96TrpSer: 0.96 ± 0.034	1.009TrpThr: 1.009 ± 0.038	1.182TrpVal: 1.182 ± 0.037	0.389TrpTrp: 0.389 ± 0.025	0.339TrpTyr: 0.339 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.568TyrAla: 2.568 ± 0.054	0.121TyrCys: 0.121 ± 0.01	1.436TyrAsp: 1.436 ± 0.034	1.149TyrGlu: 1.149 ± 0.033	0.775TyrPhe: 0.775 ± 0.028	2.004TyrGly: 2.004 ± 0.046	0.334TyrHis: 0.334 ± 0.021	0.726TyrIle: 0.726 ± 0.028	0.375TyrLys: 0.375 ± 0.022	2.293TyrLeu: 2.293 ± 0.045	0.262TyrMet: 0.262 ± 0.015	0.49TyrAsn: 0.49 ± 0.025	1.107TyrPro: 1.107 ± 0.041	0.658TyrGln: 0.658 ± 0.029	1.644TyrArg: 1.644 ± 0.042	1.187TyrSer: 1.187 ± 0.038	1.256TyrThr: 1.256 ± 0.038	1.65TyrVal: 1.65 ± 0.04	0.368TyrTrp: 0.368 ± 0.018	0.525TyrTyr: 0.525 ± 0.026	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3238 proteins (995190 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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