Amino acid dipepetide frequency for Murine polyomavirus (strain A3) (MPyV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.774AlaAla: 4.774 ± 1.31
0.434AlaCys: 0.434 ± 0.458
4.774AlaAsp: 4.774 ± 1.609
3.038AlaGlu: 3.038 ± 1.411
1.302AlaPhe: 1.302 ± 0.622
2.17AlaGly: 2.17 ± 0.689
4.34AlaHis: 4.34 ± 1.632
3.038AlaIle: 3.038 ± 1.934
1.736AlaLys: 1.736 ± 1.321
9.983AlaLeu: 9.983 ± 3.827
0.434AlaMet: 0.434 ± 0.417
0.868AlaAsn: 0.868 ± 0.574
3.472AlaPro: 3.472 ± 1.086
1.302AlaGln: 1.302 ± 0.86
3.038AlaArg: 3.038 ± 0.334
4.34AlaSer: 4.34 ± 0.93
3.906AlaThr: 3.906 ± 0.905
3.038AlaVal: 3.038 ± 0.867
0.434AlaTrp: 0.434 ± 0.287
1.736AlaTyr: 1.736 ± 0.816
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.736CysAsp: 1.736 ± 0.485
1.736CysGlu: 1.736 ± 0.849
1.302CysPhe: 1.302 ± 0.518
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
1.302CysIle: 1.302 ± 0.518
2.17CysLys: 2.17 ± 1.105
4.774CysLeu: 4.774 ± 2.47
0.0CysMet: 0.0 ± 0.0
0.434CysAsn: 0.434 ± 0.287
0.868CysPro: 0.868 ± 0.465
0.434CysGln: 0.434 ± 0.287
0.868CysArg: 0.868 ± 0.614
3.038CysSer: 3.038 ± 1.217
1.302CysThr: 1.302 ± 0.622
1.302CysVal: 1.302 ± 0.622
0.0CysTrp: 0.0 ± 0.0
1.736CysTyr: 1.736 ± 0.57
0.0CysXaa: 0.0 ± 0.0
Asp
3.038AspAla: 3.038 ± 0.69
0.0AspCys: 0.0 ± 0.0
1.736AspAsp: 1.736 ± 1.147
2.17AspGlu: 2.17 ± 0.42
4.774AspPhe: 4.774 ± 1.694
4.774AspGly: 4.774 ± 1.177
0.0AspHis: 0.0 ± 0.0
3.906AspIle: 3.906 ± 0.823
4.34AspLys: 4.34 ± 1.377
4.34AspLeu: 4.34 ± 1.098
0.868AspMet: 0.868 ± 0.917
0.434AspAsn: 0.434 ± 0.287
5.208AspPro: 5.208 ± 1.437
2.17AspGln: 2.17 ± 0.712
2.604AspArg: 2.604 ± 1.004
1.736AspSer: 1.736 ± 0.93
3.472AspThr: 3.472 ± 1.117
3.472AspVal: 3.472 ± 0.97
3.038AspTrp: 3.038 ± 1.21
1.736AspTyr: 1.736 ± 0.664
0.0AspXaa: 0.0 ± 0.0
Glu
2.17GluAla: 2.17 ± 1.04
3.038GluCys: 3.038 ± 1.051
3.906GluAsp: 3.906 ± 0.536
8.247GluGlu: 8.247 ± 2.339
1.302GluPhe: 1.302 ± 0.86
6.51GluGly: 6.51 ± 1.913
0.0GluHis: 0.0 ± 0.0
1.736GluIle: 1.736 ± 0.86
1.302GluLys: 1.302 ± 0.86
6.076GluLeu: 6.076 ± 1.935
0.0GluMet: 0.0 ± 0.0
4.774GluAsn: 4.774 ± 1.703
2.604GluPro: 2.604 ± 0.907
1.302GluGln: 1.302 ± 0.548
2.604GluArg: 2.604 ± 0.965
4.34GluSer: 4.34 ± 0.843
2.17GluThr: 2.17 ± 0.845
5.642GluVal: 5.642 ± 1.403
0.434GluTrp: 0.434 ± 0.287
1.302GluTyr: 1.302 ± 0.548
0.0GluXaa: 0.0 ± 0.0
Phe
3.038PheAla: 3.038 ± 0.939
2.604PheCys: 2.604 ± 1.037
0.868PheAsp: 0.868 ± 0.394
1.302PheGlu: 1.302 ± 0.86
0.868PhePhe: 0.868 ± 0.574
4.34PheGly: 4.34 ± 1.453
0.434PheHis: 0.434 ± 0.287
1.302PheIle: 1.302 ± 0.935
2.604PheLys: 2.604 ± 0.6
3.906PheLeu: 3.906 ± 0.941
0.434PheMet: 0.434 ± 0.386
2.17PheAsn: 2.17 ± 0.823
3.038PhePro: 3.038 ± 0.939
1.736PheGln: 1.736 ± 0.57
1.736PheArg: 1.736 ± 1.147
0.434PheSer: 0.434 ± 0.287
2.17PheThr: 2.17 ± 1.105
1.302PheVal: 1.302 ± 0.885
0.0PheTrp: 0.0 ± 0.0
0.868PheTyr: 0.868 ± 0.624
0.0PheXaa: 0.0 ± 0.0
Gly
4.34GlyAla: 4.34 ± 2.943
0.0GlyCys: 0.0 ± 0.0
4.34GlyAsp: 4.34 ± 0.682
3.906GlyGlu: 3.906 ± 1.611
2.604GlyPhe: 2.604 ± 0.37
10.851GlyGly: 10.851 ± 2.214
2.17GlyHis: 2.17 ± 0.554
1.736GlyIle: 1.736 ± 0.89
1.736GlyLys: 1.736 ± 0.849
7.812GlyLeu: 7.812 ± 2.407
2.17GlyMet: 2.17 ± 0.815
2.17GlyAsn: 2.17 ± 0.885
3.038GlyPro: 3.038 ± 1.168
1.736GlyGln: 1.736 ± 1.321
3.472GlyArg: 3.472 ± 0.464
6.944GlySer: 6.944 ± 1.798
5.642GlyThr: 5.642 ± 1.489
4.774GlyVal: 4.774 ± 1.328
1.302GlyTrp: 1.302 ± 0.648
1.736GlyTyr: 1.736 ± 0.664
0.0GlyXaa: 0.0 ± 0.0
His
4.34HisAla: 4.34 ± 1.023
0.0HisCys: 0.0 ± 0.0
1.302HisAsp: 1.302 ± 0.577
0.0HisGlu: 0.0 ± 0.0
0.868HisPhe: 0.868 ± 0.834
1.302HisGly: 1.302 ± 0.654
0.434HisHis: 0.434 ± 0.458
1.302HisIle: 1.302 ± 0.677
0.0HisLys: 0.0 ± 0.0
0.868HisLeu: 0.868 ± 0.394
0.434HisMet: 0.434 ± 0.287
0.434HisAsn: 0.434 ± 0.472
3.038HisPro: 3.038 ± 0.684
1.302HisGln: 1.302 ± 0.577
3.038HisArg: 3.038 ± 0.764
4.34HisSer: 4.34 ± 1.336
1.302HisThr: 1.302 ± 0.577
0.434HisVal: 0.434 ± 0.458
0.868HisTrp: 0.868 ± 0.465
0.868HisTyr: 0.868 ± 0.394
0.0HisXaa: 0.0 ± 0.0
Ile
1.302IleAla: 1.302 ± 0.518
1.302IleCys: 1.302 ± 0.548
1.736IleAsp: 1.736 ± 0.85
2.604IleGlu: 2.604 ± 1.536
0.0IlePhe: 0.0 ± 0.0
0.434IleGly: 0.434 ± 0.287
0.868IleHis: 0.868 ± 0.394
0.868IleIle: 0.868 ± 0.394
2.604IleLys: 2.604 ± 0.688
6.076IleLeu: 6.076 ± 2.696
1.302IleMet: 1.302 ± 0.622
1.736IleAsn: 1.736 ± 0.543
1.736IlePro: 1.736 ± 0.935
2.17IleGln: 2.17 ± 0.944
0.0IleArg: 0.0 ± 0.0
3.472IleSer: 3.472 ± 1.038
2.604IleThr: 2.604 ± 0.984
0.0IleVal: 0.0 ± 0.0
1.302IleTrp: 1.302 ± 0.465
1.302IleTyr: 1.302 ± 0.577
0.0IleXaa: 0.0 ± 0.0
Lys
2.604LysAla: 2.604 ± 1.243
3.472LysCys: 3.472 ± 0.909
3.472LysAsp: 3.472 ± 1.367
4.34LysGlu: 4.34 ± 1.607
1.302LysPhe: 1.302 ± 0.577
2.604LysGly: 2.604 ± 0.725
1.302LysHis: 1.302 ± 0.86
0.434LysIle: 0.434 ± 0.458
3.038LysLys: 3.038 ± 1.023
4.34LysLeu: 4.34 ± 1.314
0.434LysMet: 0.434 ± 0.287
1.736LysAsn: 1.736 ± 0.93
1.736LysPro: 1.736 ± 0.849
3.038LysGln: 3.038 ± 1.051
3.906LysArg: 3.906 ± 0.536
0.868LysSer: 0.868 ± 0.465
4.774LysThr: 4.774 ± 1.627
0.868LysVal: 0.868 ± 0.465
0.434LysTrp: 0.434 ± 0.287
1.736LysTyr: 1.736 ± 0.485
0.0LysXaa: 0.0 ± 0.0
Leu
5.642LeuAla: 5.642 ± 1.554
2.17LeuCys: 2.17 ± 0.464
9.115LeuAsp: 9.115 ± 1.069
7.378LeuGlu: 7.378 ± 1.847
4.774LeuPhe: 4.774 ± 1.492
6.51LeuGly: 6.51 ± 1.703
4.34LeuHis: 4.34 ± 1.175
6.076LeuIle: 6.076 ± 0.847
4.34LeuLys: 4.34 ± 1.477
17.795LeuLeu: 17.795 ± 3.141
3.038LeuMet: 3.038 ± 0.936
6.51LeuAsn: 6.51 ± 0.716
5.208LeuPro: 5.208 ± 1.353
4.34LeuGln: 4.34 ± 1.631
5.642LeuArg: 5.642 ± 2.529
6.944LeuSer: 6.944 ± 1.983
5.642LeuThr: 5.642 ± 1.403
5.642LeuVal: 5.642 ± 1.085
2.604LeuTrp: 2.604 ± 1.037
3.906LeuTyr: 3.906 ± 0.817
0.0LeuXaa: 0.0 ± 0.0
Met
2.17MetAla: 2.17 ± 1.328
0.434MetCys: 0.434 ± 0.287
1.302MetAsp: 1.302 ± 0.518
2.17MetGlu: 2.17 ± 0.96
0.0MetPhe: 0.0 ± 0.0
3.906MetGly: 3.906 ± 1.182
0.0MetHis: 0.0 ± 0.0
0.434MetIle: 0.434 ± 0.417
0.0MetLys: 0.0 ± 0.0
3.038MetLeu: 3.038 ± 0.572
0.0MetMet: 0.0 ± 0.0
1.736MetAsn: 1.736 ± 0.57
2.17MetPro: 2.17 ± 1.526
4.34MetGln: 4.34 ± 1.88
0.868MetArg: 0.868 ± 0.834
0.434MetSer: 0.434 ± 0.472
1.736MetThr: 1.736 ± 0.734
2.17MetVal: 2.17 ± 0.571
0.434MetTrp: 0.434 ± 0.458
0.434MetTyr: 0.434 ± 0.458
0.0MetXaa: 0.0 ± 0.0
Asn
1.736AsnAla: 1.736 ± 0.664
0.868AsnCys: 0.868 ± 0.574
0.434AsnAsp: 0.434 ± 0.287
2.17AsnGlu: 2.17 ± 0.801
0.434AsnPhe: 0.434 ± 0.287
2.17AsnGly: 2.17 ± 0.42
0.434AsnHis: 0.434 ± 0.287
0.868AsnIle: 0.868 ± 0.574
2.604AsnLys: 2.604 ± 1.243
6.51AsnLeu: 6.51 ± 1.871
1.302AsnMet: 1.302 ± 0.863
1.302AsnAsn: 1.302 ± 0.878
4.34AsnPro: 4.34 ± 0.861
0.868AsnGln: 0.868 ± 0.624
2.604AsnArg: 2.604 ± 2.031
1.736AsnSer: 1.736 ± 0.57
3.038AsnThr: 3.038 ± 2.187
2.604AsnVal: 2.604 ± 0.627
0.0AsnTrp: 0.0 ± 0.0
1.302AsnTyr: 1.302 ± 0.878
0.0AsnXaa: 0.0 ± 0.0
Pro
5.642ProAla: 5.642 ± 1.129
0.868ProCys: 0.868 ± 0.574
5.208ProAsp: 5.208 ± 0.928
3.038ProGlu: 3.038 ± 1.145
0.434ProPhe: 0.434 ± 0.287
3.472ProGly: 3.472 ± 1.086
0.868ProHis: 0.868 ± 0.394
2.17ProIle: 2.17 ± 1.262
2.604ProLys: 2.604 ± 0.907
4.774ProLeu: 4.774 ± 0.298
3.038ProMet: 3.038 ± 1.228
0.434ProAsn: 0.434 ± 0.287
6.51ProPro: 6.51 ± 1.312
4.34ProGln: 4.34 ± 1.454
5.642ProArg: 5.642 ± 1.209
2.604ProSer: 2.604 ± 1.313
6.076ProThr: 6.076 ± 1.226
3.472ProVal: 3.472 ± 2.053
1.302ProTrp: 1.302 ± 0.677
0.868ProTyr: 0.868 ± 0.465
0.0ProXaa: 0.0 ± 0.0
Gln
2.604GlnAla: 2.604 ± 0.627
0.434GlnCys: 0.434 ± 0.287
1.736GlnAsp: 1.736 ± 0.548
2.604GlnGlu: 2.604 ± 0.627
2.604GlnPhe: 2.604 ± 0.723
3.038GlnGly: 3.038 ± 0.657
1.736GlnHis: 1.736 ± 0.85
1.302GlnIle: 1.302 ± 0.548
1.736GlnLys: 1.736 ± 0.664
5.642GlnLeu: 5.642 ± 0.931
1.302GlnMet: 1.302 ± 0.654
0.0GlnAsn: 0.0 ± 0.0
1.736GlnPro: 1.736 ± 0.93
3.906GlnGln: 3.906 ± 1.31
4.774GlnArg: 4.774 ± 1.957
4.774GlnSer: 4.774 ± 1.564
2.17GlnThr: 2.17 ± 0.944
3.038GlnVal: 3.038 ± 1.253
0.868GlnTrp: 0.868 ± 0.614
0.868GlnTyr: 0.868 ± 0.917
0.0GlnXaa: 0.0 ± 0.0
Arg
4.774ArgAla: 4.774 ± 2.728
1.302ArgCys: 1.302 ± 0.518
3.038ArgAsp: 3.038 ± 0.764
3.038ArgGlu: 3.038 ± 0.689
1.736ArgPhe: 1.736 ± 0.485
2.604ArgGly: 2.604 ± 0.795
0.868ArgHis: 0.868 ± 0.834
1.302ArgIle: 1.302 ± 0.577
3.038ArgLys: 3.038 ± 0.771
8.247ArgLeu: 8.247 ± 2.148
4.34ArgMet: 4.34 ± 1.73
1.736ArgAsn: 1.736 ± 0.539
1.736ArgPro: 1.736 ± 0.849
3.038ArgGln: 3.038 ± 1.21
6.51ArgArg: 6.51 ± 1.4
2.604ArgSer: 2.604 ± 1.182
2.604ArgThr: 2.604 ± 0.517
3.906ArgVal: 3.906 ± 0.518
1.302ArgTrp: 1.302 ± 0.654
3.472ArgTyr: 3.472 ± 1.369
0.0ArgXaa: 0.0 ± 0.0
Ser
2.17SerAla: 2.17 ± 0.88
3.038SerCys: 3.038 ± 0.893
3.906SerAsp: 3.906 ± 0.941
3.472SerGlu: 3.472 ± 1.02
1.736SerPhe: 1.736 ± 1.147
5.208SerGly: 5.208 ± 1.021
2.17SerHis: 2.17 ± 0.788
0.434SerIle: 0.434 ± 0.287
2.17SerLys: 2.17 ± 1.06
8.681SerLeu: 8.681 ± 0.838
3.472SerMet: 3.472 ± 0.5
2.17SerAsn: 2.17 ± 0.554
4.34SerPro: 4.34 ± 1.259
3.472SerGln: 3.472 ± 1.183
3.472SerArg: 3.472 ± 0.962
7.378SerSer: 7.378 ± 1.533
3.906SerThr: 3.906 ± 1.145
5.208SerVal: 5.208 ± 0.597
0.0SerTrp: 0.0 ± 0.0
2.17SerTyr: 2.17 ± 1.042
0.0SerXaa: 0.0 ± 0.0
Thr
3.472ThrAla: 3.472 ± 1.314
1.736ThrCys: 1.736 ± 0.485
1.736ThrAsp: 1.736 ± 0.93
4.774ThrGlu: 4.774 ± 1.955
3.906ThrPhe: 3.906 ± 1.27
4.774ThrGly: 4.774 ± 0.692
1.302ThrHis: 1.302 ± 0.677
2.604ThrIle: 2.604 ± 0.93
4.774ThrLys: 4.774 ± 2.395
3.906ThrLeu: 3.906 ± 1.434
1.736ThrMet: 1.736 ± 0.51
0.434ThrAsn: 0.434 ± 0.458
7.378ThrPro: 7.378 ± 0.977
1.302ThrGln: 1.302 ± 0.654
4.774ThrArg: 4.774 ± 0.702
2.17ThrSer: 2.17 ± 0.712
1.736ThrThr: 1.736 ± 1.345
5.208ThrVal: 5.208 ± 2.113
1.302ThrTrp: 1.302 ± 0.654
0.434ThrTyr: 0.434 ± 0.417
0.0ThrXaa: 0.0 ± 0.0
Val
2.17ValAla: 2.17 ± 1.434
0.868ValCys: 0.868 ± 0.574
1.736ValAsp: 1.736 ± 0.802
1.736ValGlu: 1.736 ± 1.321
2.17ValPhe: 2.17 ± 0.801
2.17ValGly: 2.17 ± 1.328
3.906ValHis: 3.906 ± 0.518
2.17ValIle: 2.17 ± 1.194
3.472ValLys: 3.472 ± 0.909
6.51ValLeu: 6.51 ± 2.05
0.868ValMet: 0.868 ± 0.57
4.34ValAsn: 4.34 ± 1.059
3.038ValPro: 3.038 ± 0.721
2.17ValGln: 2.17 ± 0.845
3.472ValArg: 3.472 ± 1.042
4.774ValSer: 4.774 ± 1.626
4.34ValThr: 4.34 ± 1.873
4.34ValVal: 4.34 ± 1.583
1.302ValTrp: 1.302 ± 0.577
3.472ValTyr: 3.472 ± 0.859
0.0ValXaa: 0.0 ± 0.0
Trp
1.302TrpAla: 1.302 ± 0.577
0.0TrpCys: 0.0 ± 0.0
0.434TrpAsp: 0.434 ± 0.287
0.868TrpGlu: 0.868 ± 0.546
0.868TrpPhe: 0.868 ± 0.614
3.472TrpGly: 3.472 ± 1.048
0.434TrpHis: 0.434 ± 0.458
0.434TrpIle: 0.434 ± 0.287
0.434TrpLys: 0.434 ± 0.287
1.302TrpLeu: 1.302 ± 0.786
0.868TrpMet: 0.868 ± 0.624
1.736TrpAsn: 1.736 ± 0.57
0.0TrpPro: 0.0 ± 0.0
0.868TrpGln: 0.868 ± 0.624
1.302TrpArg: 1.302 ± 0.654
1.302TrpSer: 1.302 ± 0.878
0.0TrpThr: 0.0 ± 0.0
1.302TrpVal: 1.302 ± 0.654
0.0TrpTrp: 0.0 ± 0.0
0.434TrpTyr: 0.434 ± 0.287
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.868TyrAla: 0.868 ± 0.614
0.434TyrCys: 0.434 ± 0.287
1.302TyrAsp: 1.302 ± 0.878
0.868TyrGlu: 0.868 ± 0.574
2.17TyrPhe: 2.17 ± 0.823
2.17TyrGly: 2.17 ± 0.845
0.868TyrHis: 0.868 ± 0.465
0.0TyrIle: 0.0 ± 0.0
1.736TyrLys: 1.736 ± 0.485
3.472TyrLeu: 3.472 ± 1.006
1.302TyrMet: 1.302 ± 0.935
2.17TyrAsn: 2.17 ± 1.1
2.17TyrPro: 2.17 ± 1.376
3.038TyrGln: 3.038 ± 0.689
0.868TyrArg: 0.868 ± 0.624
4.34TyrSer: 4.34 ± 1.009
0.868TyrThr: 0.868 ± 0.546
1.302TyrVal: 1.302 ± 0.654
0.434TyrTrp: 0.434 ± 0.287
2.604TyrTyr: 2.604 ± 0.52
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2305 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski