Amino acid dipepetide frequency for Tortoise microvirus 16

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.436AlaAla: 3.436 ± 2.048
1.145AlaCys: 1.145 ± 0.556
4.009AlaAsp: 4.009 ± 0.976
4.009AlaGlu: 4.009 ± 1.276
4.009AlaPhe: 4.009 ± 1.513
4.009AlaGly: 4.009 ± 1.538
1.145AlaHis: 1.145 ± 0.892
1.718AlaIle: 1.718 ± 0.866
5.155AlaLys: 5.155 ± 2.201
8.591AlaLeu: 8.591 ± 1.084
2.864AlaMet: 2.864 ± 1.426
4.582AlaAsn: 4.582 ± 3.295
4.582AlaPro: 4.582 ± 1.568
2.864AlaGln: 2.864 ± 1.004
2.864AlaArg: 2.864 ± 0.491
4.582AlaSer: 4.582 ± 1.188
4.009AlaThr: 4.009 ± 1.353
5.155AlaVal: 5.155 ± 1.234
0.0AlaTrp: 0.0 ± 0.0
2.291AlaTyr: 2.291 ± 0.875
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.718CysCys: 1.718 ± 1.299
1.718CysAsp: 1.718 ± 0.986
0.0CysGlu: 0.0 ± 0.0
2.291CysPhe: 2.291 ± 1.452
1.145CysGly: 1.145 ± 0.892
0.0CysHis: 0.0 ± 0.0
0.573CysIle: 0.573 ± 0.633
2.291CysLys: 2.291 ± 1.267
2.864CysLeu: 2.864 ± 1.74
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.573CysPro: 0.573 ± 0.688
0.573CysGln: 0.573 ± 0.4
1.145CysArg: 1.145 ± 0.556
0.0CysSer: 0.0 ± 0.0
1.145CysThr: 1.145 ± 0.61
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.145CysTyr: 1.145 ± 0.892
0.0CysXaa: 0.0 ± 0.0
Asp
4.009AspAla: 4.009 ± 2.711
2.864AspCys: 2.864 ± 1.17
6.873AspAsp: 6.873 ± 1.538
3.436AspGlu: 3.436 ± 0.745
5.155AspPhe: 5.155 ± 1.855
2.291AspGly: 2.291 ± 1.102
0.573AspHis: 0.573 ± 0.688
6.873AspIle: 6.873 ± 2.133
2.864AspLys: 2.864 ± 1.257
4.009AspLeu: 4.009 ± 0.83
0.573AspMet: 0.573 ± 0.4
4.009AspAsn: 4.009 ± 0.747
1.718AspPro: 1.718 ± 0.567
1.145AspGln: 1.145 ± 0.993
3.436AspArg: 3.436 ± 0.745
4.582AspSer: 4.582 ± 2.873
4.009AspThr: 4.009 ± 1.349
2.864AspVal: 2.864 ± 1.645
0.573AspTrp: 0.573 ± 0.544
5.727AspTyr: 5.727 ± 1.882
0.0AspXaa: 0.0 ± 0.0
Glu
4.009GluAla: 4.009 ± 2.158
0.0GluCys: 0.0 ± 0.0
1.718GluAsp: 1.718 ± 0.687
1.145GluGlu: 1.145 ± 0.993
0.573GluPhe: 0.573 ± 0.688
0.573GluGly: 0.573 ± 0.688
0.0GluHis: 0.0 ± 0.0
3.436GluIle: 3.436 ± 0.526
1.718GluLys: 1.718 ± 0.894
8.591GluLeu: 8.591 ± 1.577
1.718GluMet: 1.718 ± 1.085
1.145GluAsn: 1.145 ± 0.571
2.291GluPro: 2.291 ± 1.193
0.573GluGln: 0.573 ± 0.497
3.436GluArg: 3.436 ± 1.075
4.009GluSer: 4.009 ± 1.959
2.864GluThr: 2.864 ± 0.819
2.864GluVal: 2.864 ± 1.46
0.573GluTrp: 0.573 ± 0.624
2.291GluTyr: 2.291 ± 1.617
0.0GluXaa: 0.0 ± 0.0
Phe
4.582PheAla: 4.582 ± 1.406
1.718PheCys: 1.718 ± 1.511
6.3PheAsp: 6.3 ± 2.731
1.718PheGlu: 1.718 ± 0.7
3.436PhePhe: 3.436 ± 1.502
2.864PheGly: 2.864 ± 0.491
1.145PheHis: 1.145 ± 0.884
1.145PheIle: 1.145 ± 0.556
3.436PheLys: 3.436 ± 1.471
4.009PheLeu: 4.009 ± 0.904
1.718PheMet: 1.718 ± 1.336
2.864PheAsn: 2.864 ± 0.91
2.864PhePro: 2.864 ± 0.616
2.291PheGln: 2.291 ± 0.577
4.009PheArg: 4.009 ± 1.293
3.436PheSer: 3.436 ± 0.917
4.009PheThr: 4.009 ± 1.574
2.864PheVal: 2.864 ± 1.567
0.0PheTrp: 0.0 ± 0.0
4.582PheTyr: 4.582 ± 1.377
0.0PheXaa: 0.0 ± 0.0
Gly
3.436GlyAla: 3.436 ± 1.559
0.573GlyCys: 0.573 ± 0.4
1.718GlyAsp: 1.718 ± 1.132
2.291GlyGlu: 2.291 ± 1.447
4.009GlyPhe: 4.009 ± 1.604
2.864GlyGly: 2.864 ± 1.82
1.145GlyHis: 1.145 ± 0.706
5.727GlyIle: 5.727 ± 2.245
3.436GlyLys: 3.436 ± 1.173
6.873GlyLeu: 6.873 ± 1.944
0.0GlyMet: 0.0 ± 0.0
1.145GlyAsn: 1.145 ± 0.8
0.0GlyPro: 0.0 ± 0.0
0.573GlyGln: 0.573 ± 0.497
1.718GlyArg: 1.718 ± 0.445
8.018GlySer: 8.018 ± 1.825
2.864GlyThr: 2.864 ± 1.506
2.291GlyVal: 2.291 ± 1.045
0.573GlyTrp: 0.573 ± 0.4
4.582GlyTyr: 4.582 ± 0.881
0.0GlyXaa: 0.0 ± 0.0
His
2.864HisAla: 2.864 ± 0.876
0.0HisCys: 0.0 ± 0.0
0.573HisAsp: 0.573 ± 0.703
0.573HisGlu: 0.573 ± 0.624
0.573HisPhe: 0.573 ± 0.633
1.718HisGly: 1.718 ± 1.336
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.0HisLys: 0.0 ± 0.0
1.145HisLeu: 1.145 ± 0.456
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.573HisPro: 0.573 ± 0.592
0.0HisGln: 0.0 ± 0.0
1.145HisArg: 1.145 ± 0.706
2.864HisSer: 2.864 ± 1.28
1.145HisThr: 1.145 ± 0.8
0.0HisVal: 0.0 ± 0.0
0.573HisTrp: 0.573 ± 0.544
1.718HisTyr: 1.718 ± 1.511
0.0HisXaa: 0.0 ± 0.0
Ile
5.155IleAla: 5.155 ± 1.856
0.0IleCys: 0.0 ± 0.0
2.291IleAsp: 2.291 ± 1.993
2.864IleGlu: 2.864 ± 1.839
2.291IlePhe: 2.291 ± 0.82
2.291IleGly: 2.291 ± 1.112
1.718IleHis: 1.718 ± 0.7
0.573IleIle: 0.573 ± 0.4
1.145IleLys: 1.145 ± 0.785
4.009IleLeu: 4.009 ± 1.396
2.291IleMet: 2.291 ± 1.444
2.291IleAsn: 2.291 ± 0.806
4.009IlePro: 4.009 ± 1.869
0.573IleGln: 0.573 ± 0.497
3.436IleArg: 3.436 ± 1.204
5.727IleSer: 5.727 ± 1.846
1.145IleThr: 1.145 ± 0.706
2.291IleVal: 2.291 ± 1.019
0.573IleTrp: 0.573 ± 0.4
3.436IleTyr: 3.436 ± 1.66
0.0IleXaa: 0.0 ± 0.0
Lys
2.864LysAla: 2.864 ± 1.071
0.0LysCys: 0.0 ± 0.0
2.864LysAsp: 2.864 ± 1.569
2.291LysGlu: 2.291 ± 0.655
1.145LysPhe: 1.145 ± 0.811
2.864LysGly: 2.864 ± 0.836
0.573LysHis: 0.573 ± 0.703
0.573LysIle: 0.573 ± 0.592
1.145LysLys: 1.145 ± 1.029
4.009LysLeu: 4.009 ± 1.969
0.573LysMet: 0.573 ± 0.72
2.864LysAsn: 2.864 ± 1.204
1.145LysPro: 1.145 ± 0.571
1.145LysGln: 1.145 ± 0.884
4.009LysArg: 4.009 ± 2.202
2.864LysSer: 2.864 ± 1.35
2.864LysThr: 2.864 ± 0.8
4.009LysVal: 4.009 ± 0.802
0.0LysTrp: 0.0 ± 0.0
1.145LysTyr: 1.145 ± 1.088
0.0LysXaa: 0.0 ± 0.0
Leu
6.873LeuAla: 6.873 ± 2.042
0.573LeuCys: 0.573 ± 0.592
6.873LeuAsp: 6.873 ± 1.639
4.582LeuGlu: 4.582 ± 0.814
5.155LeuPhe: 5.155 ± 2.022
5.155LeuGly: 5.155 ± 1.979
1.718LeuHis: 1.718 ± 0.924
3.436LeuIle: 3.436 ± 1.503
5.727LeuLys: 5.727 ± 2.094
3.436LeuLeu: 3.436 ± 0.874
1.718LeuMet: 1.718 ± 0.866
2.864LeuAsn: 2.864 ± 1.506
6.873LeuPro: 6.873 ± 2.295
1.718LeuGln: 1.718 ± 1.2
6.873LeuArg: 6.873 ± 1.096
10.882LeuSer: 10.882 ± 2.308
7.446LeuThr: 7.446 ± 0.909
5.727LeuVal: 5.727 ± 1.258
1.145LeuTrp: 1.145 ± 0.8
4.582LeuTyr: 4.582 ± 1.31
0.0LeuXaa: 0.0 ± 0.0
Met
1.718MetAla: 1.718 ± 0.665
0.573MetCys: 0.573 ± 0.688
2.291MetAsp: 2.291 ± 0.577
1.145MetGlu: 1.145 ± 0.785
1.145MetPhe: 1.145 ± 0.684
1.718MetGly: 1.718 ± 0.812
0.0MetHis: 0.0 ± 0.0
0.573MetIle: 0.573 ± 0.633
1.145MetLys: 1.145 ± 0.951
4.582MetLeu: 4.582 ± 1.587
1.718MetMet: 1.718 ± 0.704
1.718MetAsn: 1.718 ± 0.7
1.145MetPro: 1.145 ± 0.456
1.718MetGln: 1.718 ± 1.49
1.718MetArg: 1.718 ± 0.759
2.864MetSer: 2.864 ± 0.719
2.291MetThr: 2.291 ± 1.515
0.0MetVal: 0.0 ± 0.0
0.573MetTrp: 0.573 ± 0.4
0.573MetTyr: 0.573 ± 0.4
0.0MetXaa: 0.0 ± 0.0
Asn
4.009AsnAla: 4.009 ± 1.515
0.0AsnCys: 0.0 ± 0.0
2.864AsnAsp: 2.864 ± 1.506
0.0AsnGlu: 0.0 ± 0.0
1.718AsnPhe: 1.718 ± 0.853
2.291AsnGly: 2.291 ± 1.543
0.573AsnHis: 0.573 ± 0.624
2.291AsnIle: 2.291 ± 0.913
2.864AsnLys: 2.864 ± 0.887
5.155AsnLeu: 5.155 ± 1.215
1.718AsnMet: 1.718 ± 0.801
2.291AsnAsn: 2.291 ± 0.913
2.864AsnPro: 2.864 ± 0.819
3.436AsnGln: 3.436 ± 0.745
2.291AsnArg: 2.291 ± 1.466
1.145AsnSer: 1.145 ± 0.8
2.864AsnThr: 2.864 ± 1.141
0.0AsnVal: 0.0 ± 0.0
0.0AsnTrp: 0.0 ± 0.0
3.436AsnTyr: 3.436 ± 1.005
0.0AsnXaa: 0.0 ± 0.0
Pro
0.573ProAla: 0.573 ± 0.4
1.145ProCys: 1.145 ± 0.968
3.436ProAsp: 3.436 ± 1.386
2.291ProGlu: 2.291 ± 1.452
3.436ProPhe: 3.436 ± 0.921
1.145ProGly: 1.145 ± 0.993
0.573ProHis: 0.573 ± 0.497
3.436ProIle: 3.436 ± 1.517
1.145ProLys: 1.145 ± 0.884
8.018ProLeu: 8.018 ± 1.095
0.573ProMet: 0.573 ± 0.4
1.718ProAsn: 1.718 ± 0.986
0.573ProPro: 0.573 ± 0.592
2.291ProGln: 2.291 ± 0.913
2.291ProArg: 2.291 ± 0.903
6.873ProSer: 6.873 ± 2.347
4.009ProThr: 4.009 ± 1.547
1.718ProVal: 1.718 ± 0.702
0.0ProTrp: 0.0 ± 0.0
2.291ProTyr: 2.291 ± 1.6
0.0ProXaa: 0.0 ± 0.0
Gln
3.436GlnAla: 3.436 ± 2.31
0.0GlnCys: 0.0 ± 0.0
1.718GlnAsp: 1.718 ± 0.7
1.718GlnGlu: 1.718 ± 1.49
2.864GlnPhe: 2.864 ± 0.719
0.573GlnGly: 0.573 ± 0.4
0.0GlnHis: 0.0 ± 0.0
1.718GlnIle: 1.718 ± 0.7
1.145GlnLys: 1.145 ± 0.993
0.573GlnLeu: 0.573 ± 0.497
1.718GlnMet: 1.718 ± 0.445
1.718GlnAsn: 1.718 ± 0.801
0.573GlnPro: 0.573 ± 0.4
5.155GlnGln: 5.155 ± 3.789
5.727GlnArg: 5.727 ± 2.108
4.582GlnSer: 4.582 ± 1.499
4.009GlnThr: 4.009 ± 1.392
1.718GlnVal: 1.718 ± 0.787
0.573GlnTrp: 0.573 ± 0.497
0.573GlnTyr: 0.573 ± 0.497
0.0GlnXaa: 0.0 ± 0.0
Arg
5.155ArgAla: 5.155 ± 0.871
1.718ArgCys: 1.718 ± 1.221
4.009ArgAsp: 4.009 ± 1.144
4.009ArgGlu: 4.009 ± 1.261
3.436ArgPhe: 3.436 ± 2.036
2.864ArgGly: 2.864 ± 1.592
0.0ArgHis: 0.0 ± 0.0
2.864ArgIle: 2.864 ± 1.125
1.718ArgLys: 1.718 ± 1.557
5.727ArgLeu: 5.727 ± 1.335
3.436ArgMet: 3.436 ± 1.005
4.009ArgAsn: 4.009 ± 1.301
3.436ArgPro: 3.436 ± 0.98
2.864ArgGln: 2.864 ± 1.82
3.436ArgArg: 3.436 ± 0.985
6.873ArgSer: 6.873 ± 1.978
0.573ArgThr: 0.573 ± 0.497
1.718ArgVal: 1.718 ± 1.296
1.145ArgTrp: 1.145 ± 0.456
3.436ArgTyr: 3.436 ± 0.806
0.0ArgXaa: 0.0 ± 0.0
Ser
6.873SerAla: 6.873 ± 2.18
1.145SerCys: 1.145 ± 0.556
6.3SerAsp: 6.3 ± 0.828
6.3SerGlu: 6.3 ± 1.768
6.3SerPhe: 6.3 ± 1.741
8.591SerGly: 8.591 ± 2.59
3.436SerHis: 3.436 ± 0.98
5.727SerIle: 5.727 ± 1.402
0.573SerLys: 0.573 ± 0.4
5.155SerLeu: 5.155 ± 1.678
4.009SerMet: 4.009 ± 1.654
4.582SerAsn: 4.582 ± 1.611
5.155SerPro: 5.155 ± 2.609
2.864SerGln: 2.864 ± 1.112
5.727SerArg: 5.727 ± 0.781
14.318SerSer: 14.318 ± 3.082
5.727SerThr: 5.727 ± 0.917
4.582SerVal: 4.582 ± 2.283
1.145SerTrp: 1.145 ± 0.83
4.009SerTyr: 4.009 ± 0.945
0.0SerXaa: 0.0 ± 0.0
Thr
5.727ThrAla: 5.727 ± 1.521
1.145ThrCys: 1.145 ± 0.757
2.291ThrAsp: 2.291 ± 1.207
0.573ThrGlu: 0.573 ± 0.688
5.727ThrPhe: 5.727 ± 2.153
4.582ThrGly: 4.582 ± 1.358
0.0ThrHis: 0.0 ± 0.0
3.436ThrIle: 3.436 ± 0.978
1.145ThrLys: 1.145 ± 0.456
4.009ThrLeu: 4.009 ± 1.363
1.145ThrMet: 1.145 ± 0.597
2.291ThrAsn: 2.291 ± 0.817
2.864ThrPro: 2.864 ± 1.497
4.009ThrGln: 4.009 ± 1.734
2.864ThrArg: 2.864 ± 1.323
6.3ThrSer: 6.3 ± 1.533
4.009ThrThr: 4.009 ± 2.194
3.436ThrVal: 3.436 ± 0.711
0.573ThrTrp: 0.573 ± 0.4
3.436ThrTyr: 3.436 ± 1.037
0.0ThrXaa: 0.0 ± 0.0
Val
3.436ValAla: 3.436 ± 1.147
1.145ValCys: 1.145 ± 0.951
5.155ValAsp: 5.155 ± 1.585
2.864ValGlu: 2.864 ± 1.865
1.718ValPhe: 1.718 ± 1.157
2.864ValGly: 2.864 ± 1.222
0.573ValHis: 0.573 ± 0.592
1.145ValIle: 1.145 ± 0.456
1.718ValLys: 1.718 ± 0.804
4.582ValLeu: 4.582 ± 2.039
1.145ValMet: 1.145 ± 0.724
0.0ValAsn: 0.0 ± 0.0
4.582ValPro: 4.582 ± 1.611
1.718ValGln: 1.718 ± 0.789
2.291ValArg: 2.291 ± 1.21
6.873ValSer: 6.873 ± 1.214
1.718ValThr: 1.718 ± 1.2
3.436ValVal: 3.436 ± 1.34
0.573ValTrp: 0.573 ± 0.688
0.573ValTyr: 0.573 ± 0.4
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.573TrpCys: 0.573 ± 0.688
0.0TrpAsp: 0.0 ± 0.0
0.573TrpGlu: 0.573 ± 0.624
0.573TrpPhe: 0.573 ± 0.4
0.573TrpGly: 0.573 ± 0.4
0.573TrpHis: 0.573 ± 0.688
0.573TrpIle: 0.573 ± 0.4
0.0TrpLys: 0.0 ± 0.0
1.718TrpLeu: 1.718 ± 1.054
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.573TrpPro: 0.573 ± 0.4
0.0TrpGln: 0.0 ± 0.0
2.291TrpArg: 2.291 ± 0.827
0.573TrpSer: 0.573 ± 0.4
0.573TrpThr: 0.573 ± 0.4
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.864TyrAla: 2.864 ± 1.401
1.145TyrCys: 1.145 ± 0.722
4.582TyrAsp: 4.582 ± 2.186
1.145TyrGlu: 1.145 ± 0.785
3.436TyrPhe: 3.436 ± 1.147
2.864TyrGly: 2.864 ± 0.941
1.718TyrHis: 1.718 ± 0.812
2.291TyrIle: 2.291 ± 1.112
1.145TyrLys: 1.145 ± 0.892
6.3TyrLeu: 6.3 ± 2.156
1.718TyrMet: 1.718 ± 0.696
1.718TyrAsn: 1.718 ± 0.894
1.145TyrPro: 1.145 ± 1.029
4.582TyrGln: 4.582 ± 1.177
1.718TyrArg: 1.718 ± 0.445
5.155TyrSer: 5.155 ± 1.979
2.291TyrThr: 2.291 ± 0.806
3.436TyrVal: 3.436 ± 1.63
0.573TyrTrp: 0.573 ± 0.4
1.718TyrTyr: 1.718 ± 0.801
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (1747 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski