Amino acid dipepetide frequency for Lonestar tick chuvirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.277AlaAla: 7.277 ± 4.942
1.516AlaCys: 1.516 ± 0.661
2.729AlaAsp: 2.729 ± 1.014
5.458AlaGlu: 5.458 ± 1.204
4.245AlaPhe: 4.245 ± 1.188
3.032AlaGly: 3.032 ± 1.79
1.516AlaHis: 1.516 ± 0.62
3.639AlaIle: 3.639 ± 0.848
3.942AlaLys: 3.942 ± 1.593
6.367AlaLeu: 6.367 ± 0.953
1.516AlaMet: 1.516 ± 1.36
3.639AlaAsn: 3.639 ± 1.06
2.426AlaPro: 2.426 ± 0.387
2.729AlaGln: 2.729 ± 1.014
2.426AlaArg: 2.426 ± 0.947
4.851AlaSer: 4.851 ± 1.539
4.245AlaThr: 4.245 ± 0.989
6.367AlaVal: 6.367 ± 2.433
0.91AlaTrp: 0.91 ± 0.308
3.032AlaTyr: 3.032 ± 1.847
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.213CysCys: 1.213 ± 0.666
1.213CysAsp: 1.213 ± 0.347
1.213CysGlu: 1.213 ± 1.694
0.606CysPhe: 0.606 ± 0.333
1.213CysGly: 1.213 ± 0.363
0.606CysHis: 0.606 ± 0.325
1.819CysIle: 1.819 ± 0.807
1.213CysLys: 1.213 ± 0.65
4.245CysLeu: 4.245 ± 1.0
0.91CysMet: 0.91 ± 0.488
0.606CysAsn: 0.606 ± 0.333
0.606CysPro: 0.606 ± 0.325
0.91CysGln: 0.91 ± 0.308
0.606CysArg: 0.606 ± 0.333
3.032CysSer: 3.032 ± 1.664
0.606CysThr: 0.606 ± 0.325
0.91CysVal: 0.91 ± 0.488
0.0CysTrp: 0.0 ± 0.0
2.122CysTyr: 2.122 ± 0.343
0.0CysXaa: 0.0 ± 0.0
Asp
4.245AspAla: 4.245 ± 2.882
0.606AspCys: 0.606 ± 0.333
3.032AspAsp: 3.032 ± 0.898
3.942AspGlu: 3.942 ± 1.24
1.213AspPhe: 1.213 ± 0.452
3.639AspGly: 3.639 ± 1.566
1.516AspHis: 1.516 ± 0.804
3.639AspIle: 3.639 ± 1.124
1.516AspLys: 1.516 ± 1.151
3.032AspLeu: 3.032 ± 1.023
1.819AspMet: 1.819 ± 0.257
1.213AspAsn: 1.213 ± 0.452
3.032AspPro: 3.032 ± 1.209
1.516AspGln: 1.516 ± 0.259
2.729AspArg: 2.729 ± 0.399
1.819AspSer: 1.819 ± 1.236
2.122AspThr: 2.122 ± 0.748
4.245AspVal: 4.245 ± 1.315
0.303AspTrp: 0.303 ± 0.163
3.032AspTyr: 3.032 ± 1.625
0.0AspXaa: 0.0 ± 0.0
Glu
3.942GluAla: 3.942 ± 2.92
1.819GluCys: 1.819 ± 0.616
4.245GluAsp: 4.245 ± 1.877
4.548GluGlu: 4.548 ± 0.774
2.426GluPhe: 2.426 ± 0.939
3.942GluGly: 3.942 ± 0.768
2.729GluHis: 2.729 ± 0.735
2.122GluIle: 2.122 ± 1.138
2.122GluLys: 2.122 ± 0.947
6.367GluLeu: 6.367 ± 1.42
2.122GluMet: 2.122 ± 0.871
1.213GluAsn: 1.213 ± 0.65
0.91GluPro: 0.91 ± 0.308
3.032GluGln: 3.032 ± 0.655
4.245GluArg: 4.245 ± 1.782
3.942GluSer: 3.942 ± 1.24
3.032GluThr: 3.032 ± 0.941
4.851GluVal: 4.851 ± 0.666
1.516GluTrp: 1.516 ± 0.259
2.122GluTyr: 2.122 ± 0.748
0.0GluXaa: 0.0 ± 0.0
Phe
2.122PheAla: 2.122 ± 0.94
0.303PheCys: 0.303 ± 0.424
2.729PheAsp: 2.729 ± 0.617
2.426PheGlu: 2.426 ± 0.472
0.91PhePhe: 0.91 ± 0.488
1.213PheGly: 1.213 ± 0.363
0.91PheHis: 0.91 ± 0.308
1.213PheIle: 1.213 ± 0.363
1.213PheLys: 1.213 ± 1.1
5.761PheLeu: 5.761 ± 1.384
1.516PheMet: 1.516 ± 0.62
0.91PheAsn: 0.91 ± 1.194
2.729PhePro: 2.729 ± 0.602
1.819PheGln: 1.819 ± 0.998
3.032PheArg: 3.032 ± 0.941
3.942PheSer: 3.942 ± 1.26
1.819PheThr: 1.819 ± 0.975
4.245PheVal: 4.245 ± 0.983
0.606PheTrp: 0.606 ± 0.333
1.213PheTyr: 1.213 ± 0.363
0.0PheXaa: 0.0 ± 0.0
Gly
2.426GlyAla: 2.426 ± 1.48
1.516GlyCys: 1.516 ± 0.471
3.032GlyAsp: 3.032 ± 0.655
3.335GlyGlu: 3.335 ± 0.58
3.032GlyPhe: 3.032 ± 1.023
1.819GlyGly: 1.819 ± 1.236
1.516GlyHis: 1.516 ± 0.471
2.426GlyIle: 2.426 ± 0.387
2.426GlyLys: 2.426 ± 0.726
5.458GlyLeu: 5.458 ± 1.037
0.91GlyMet: 0.91 ± 0.744
1.516GlyAsn: 1.516 ± 0.546
1.819GlyPro: 1.819 ± 0.616
3.032GlyGln: 3.032 ± 1.493
2.426GlyArg: 2.426 ± 1.48
2.729GlySer: 2.729 ± 0.924
4.851GlyThr: 4.851 ± 1.354
3.335GlyVal: 3.335 ± 3.129
0.91GlyTrp: 0.91 ± 1.194
2.426GlyTyr: 2.426 ± 0.921
0.0GlyXaa: 0.0 ± 0.0
His
1.213HisAla: 1.213 ± 0.363
1.213HisCys: 1.213 ± 0.666
0.606HisAsp: 0.606 ± 0.325
2.426HisGlu: 2.426 ± 0.472
1.819HisPhe: 1.819 ± 0.603
1.516HisGly: 1.516 ± 0.62
0.91HisHis: 0.91 ± 0.488
1.213HisIle: 1.213 ± 0.834
1.213HisLys: 1.213 ± 0.363
2.729HisLeu: 2.729 ± 0.825
0.303HisMet: 0.303 ± 0.424
1.516HisAsn: 1.516 ± 0.813
1.213HisPro: 1.213 ± 0.363
1.213HisGln: 1.213 ± 0.363
0.91HisArg: 0.91 ± 0.488
3.032HisSer: 3.032 ± 1.241
1.213HisThr: 1.213 ± 0.347
3.639HisVal: 3.639 ± 0.849
0.606HisTrp: 0.606 ± 0.417
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.548IleAla: 4.548 ± 0.873
0.606IleCys: 0.606 ± 0.325
3.032IleAsp: 3.032 ± 0.955
2.122IleGlu: 2.122 ± 1.207
1.213IlePhe: 1.213 ± 0.363
3.032IleGly: 3.032 ± 0.916
1.516IleHis: 1.516 ± 0.471
2.426IleIle: 2.426 ± 0.695
2.729IleLys: 2.729 ± 0.602
5.458IleLeu: 5.458 ± 1.227
1.213IleMet: 1.213 ± 0.452
1.819IleAsn: 1.819 ± 1.168
2.122IlePro: 2.122 ± 0.748
2.426IleGln: 2.426 ± 0.726
2.729IleArg: 2.729 ± 1.463
4.851IleSer: 4.851 ± 1.854
3.335IleThr: 3.335 ± 0.489
3.639IleVal: 3.639 ± 1.089
0.303IleTrp: 0.303 ± 0.163
2.426IleTyr: 2.426 ± 0.387
0.0IleXaa: 0.0 ± 0.0
Lys
3.032LysAla: 3.032 ± 0.941
1.516LysCys: 1.516 ± 0.471
1.819LysAsp: 1.819 ± 1.168
1.516LysGlu: 1.516 ± 0.813
2.122LysPhe: 2.122 ± 0.748
3.335LysGly: 3.335 ± 0.924
2.122LysHis: 2.122 ± 0.653
3.335LysIle: 3.335 ± 1.367
3.335LysLys: 3.335 ± 1.788
4.548LysLeu: 4.548 ± 0.905
2.122LysMet: 2.122 ± 1.393
1.819LysAsn: 1.819 ± 0.692
3.032LysPro: 3.032 ± 1.135
1.213LysGln: 1.213 ± 0.347
1.819LysArg: 1.819 ± 1.236
3.032LysSer: 3.032 ± 1.33
2.426LysThr: 2.426 ± 0.726
4.245LysVal: 4.245 ± 1.877
0.91LysTrp: 0.91 ± 0.744
1.819LysTyr: 1.819 ± 2.371
0.0LysXaa: 0.0 ± 0.0
Leu
6.064LeuAla: 6.064 ± 1.925
2.122LeuCys: 2.122 ± 0.439
5.458LeuAsp: 5.458 ± 0.876
5.458LeuGlu: 5.458 ± 2.106
3.942LeuPhe: 3.942 ± 1.26
5.761LeuGly: 5.761 ± 1.321
2.122LeuHis: 2.122 ± 0.748
2.426LeuIle: 2.426 ± 0.472
4.245LeuLys: 4.245 ± 1.4
10.612LeuLeu: 10.612 ± 1.35
2.426LeuMet: 2.426 ± 0.59
1.516LeuAsn: 1.516 ± 0.546
6.974LeuPro: 6.974 ± 1.593
3.335LeuGln: 3.335 ± 1.28
6.064LeuArg: 6.064 ± 1.206
9.703LeuSer: 9.703 ± 0.816
6.064LeuThr: 6.064 ± 0.941
7.884LeuVal: 7.884 ± 2.756
1.819LeuTrp: 1.819 ± 0.667
4.245LeuTyr: 4.245 ± 1.782
0.0LeuXaa: 0.0 ± 0.0
Met
2.426MetAla: 2.426 ± 0.387
0.606MetCys: 0.606 ± 0.417
1.516MetAsp: 1.516 ± 0.661
1.213MetGlu: 1.213 ± 0.363
1.516MetPhe: 1.516 ± 0.259
1.213MetGly: 1.213 ± 0.65
0.91MetHis: 0.91 ± 0.308
1.213MetIle: 1.213 ± 0.452
1.516MetLys: 1.516 ± 0.813
1.516MetLeu: 1.516 ± 1.172
0.606MetMet: 0.606 ± 0.417
0.91MetAsn: 0.91 ± 0.477
1.819MetPro: 1.819 ± 0.807
2.729MetGln: 2.729 ± 1.014
1.213MetArg: 1.213 ± 0.452
2.729MetSer: 2.729 ± 1.027
1.213MetThr: 1.213 ± 0.834
2.729MetVal: 2.729 ± 0.968
0.606MetTrp: 0.606 ± 0.333
1.213MetTyr: 1.213 ± 1.1
0.0MetXaa: 0.0 ± 0.0
Asn
1.213AsnAla: 1.213 ± 0.65
1.819AsnCys: 1.819 ± 0.257
0.606AsnAsp: 0.606 ± 0.417
2.426AsnGlu: 2.426 ± 1.266
2.426AsnPhe: 2.426 ± 0.726
0.606AsnGly: 0.606 ± 0.847
0.303AsnHis: 0.303 ± 0.488
2.426AsnIle: 2.426 ± 2.446
1.516AsnLys: 1.516 ± 0.813
2.122AsnLeu: 2.122 ± 0.841
0.91AsnMet: 0.91 ± 0.403
0.606AsnAsn: 0.606 ± 0.325
1.819AsnPro: 1.819 ± 1.236
0.606AsnGln: 0.606 ± 0.622
2.122AsnArg: 2.122 ± 0.343
1.516AsnSer: 1.516 ± 1.096
1.819AsnThr: 1.819 ± 0.667
3.639AsnVal: 3.639 ± 1.646
0.606AsnTrp: 0.606 ± 0.417
1.516AsnTyr: 1.516 ± 0.471
0.0AsnXaa: 0.0 ± 0.0
Pro
3.032ProAla: 3.032 ± 1.709
1.213ProCys: 1.213 ± 0.363
2.729ProAsp: 2.729 ± 1.463
3.335ProGlu: 3.335 ± 0.729
2.426ProPhe: 2.426 ± 0.726
1.213ProGly: 1.213 ± 0.666
0.91ProHis: 0.91 ± 0.403
3.335ProIle: 3.335 ± 1.07
1.819ProLys: 1.819 ± 1.236
4.851ProLeu: 4.851 ± 1.29
0.303ProMet: 0.303 ± 0.424
0.91ProAsn: 0.91 ± 0.488
4.245ProPro: 4.245 ± 1.107
1.516ProGln: 1.516 ± 0.62
3.942ProArg: 3.942 ± 0.581
3.335ProSer: 3.335 ± 0.838
3.032ProThr: 3.032 ± 0.674
4.245ProVal: 4.245 ± 1.293
0.303ProTrp: 0.303 ± 0.163
2.122ProTyr: 2.122 ± 0.803
0.0ProXaa: 0.0 ± 0.0
Gln
4.851GlnAla: 4.851 ± 1.813
0.91GlnCys: 0.91 ± 0.308
1.213GlnAsp: 1.213 ± 0.363
2.729GlnGlu: 2.729 ± 1.276
0.606GlnPhe: 0.606 ± 0.325
0.91GlnGly: 0.91 ± 0.403
2.122GlnHis: 2.122 ± 0.748
2.426GlnIle: 2.426 ± 0.899
1.819GlnLys: 1.819 ± 1.057
5.155GlnLeu: 5.155 ± 3.107
1.819GlnMet: 1.819 ± 0.953
0.91GlnAsn: 0.91 ± 1.465
2.729GlnPro: 2.729 ± 1.234
1.516GlnGln: 1.516 ± 0.546
2.122GlnArg: 2.122 ± 0.343
2.426GlnSer: 2.426 ± 0.726
1.516GlnThr: 1.516 ± 1.151
2.729GlnVal: 2.729 ± 1.21
0.303GlnTrp: 0.303 ± 0.163
1.819GlnTyr: 1.819 ± 2.387
0.0GlnXaa: 0.0 ± 0.0
Arg
5.155ArgAla: 5.155 ± 1.386
0.606ArgCys: 0.606 ± 0.417
2.122ArgAsp: 2.122 ± 1.152
3.639ArgGlu: 3.639 ± 1.089
2.122ArgPhe: 2.122 ± 0.748
3.032ArgGly: 3.032 ± 1.847
1.213ArgHis: 1.213 ± 0.65
3.942ArgIle: 3.942 ± 1.939
3.032ArgLys: 3.032 ± 0.768
4.548ArgLeu: 4.548 ± 0.905
1.819ArgMet: 1.819 ± 0.807
0.303ArgAsn: 0.303 ± 0.163
1.516ArgPro: 1.516 ± 0.546
3.639ArgGln: 3.639 ± 0.665
3.032ArgArg: 3.032 ± 0.941
4.851ArgSer: 4.851 ± 1.728
3.942ArgThr: 3.942 ± 1.378
5.458ArgVal: 5.458 ± 1.646
0.606ArgTrp: 0.606 ± 0.325
0.91ArgTyr: 0.91 ± 0.488
0.0ArgXaa: 0.0 ± 0.0
Ser
5.761SerAla: 5.761 ± 1.023
1.516SerCys: 1.516 ± 0.813
3.032SerAsp: 3.032 ± 1.362
3.032SerGlu: 3.032 ± 1.625
3.942SerPhe: 3.942 ± 1.84
4.245SerGly: 4.245 ± 1.865
2.729SerHis: 2.729 ± 0.924
3.032SerIle: 3.032 ± 0.768
6.671SerLys: 6.671 ± 1.103
5.155SerLeu: 5.155 ± 1.239
2.122SerMet: 2.122 ± 0.876
1.213SerAsn: 1.213 ± 1.157
3.335SerPro: 3.335 ± 1.548
1.819SerGln: 1.819 ± 0.953
3.032SerArg: 3.032 ± 0.471
4.245SerSer: 4.245 ± 2.286
5.155SerThr: 5.155 ± 3.196
5.761SerVal: 5.761 ± 1.865
0.91SerTrp: 0.91 ± 0.488
3.942SerTyr: 3.942 ± 1.184
0.0SerXaa: 0.0 ± 0.0
Thr
2.729ThrAla: 2.729 ± 0.815
2.122ThrCys: 2.122 ± 0.748
3.032ThrAsp: 3.032 ± 1.33
4.245ThrGlu: 4.245 ± 1.675
1.213ThrPhe: 1.213 ± 0.452
2.729ThrGly: 2.729 ± 0.965
1.819ThrHis: 1.819 ± 0.975
5.458ThrIle: 5.458 ± 1.006
2.729ThrLys: 2.729 ± 0.825
6.671ThrLeu: 6.671 ± 1.299
0.303ThrMet: 0.303 ± 0.424
2.426ThrAsn: 2.426 ± 0.59
2.426ThrPro: 2.426 ± 0.824
3.032ThrGln: 3.032 ± 0.916
4.851ThrArg: 4.851 ± 1.26
3.335ThrSer: 3.335 ± 1.011
5.155ThrThr: 5.155 ± 1.546
4.245ThrVal: 4.245 ± 0.989
0.606ThrTrp: 0.606 ± 0.333
2.729ThrTyr: 2.729 ± 0.924
0.0ThrXaa: 0.0 ± 0.0
Val
8.793ValAla: 8.793 ± 1.812
1.516ValCys: 1.516 ± 0.62
3.335ValAsp: 3.335 ± 0.923
5.458ValGlu: 5.458 ± 0.798
3.639ValPhe: 3.639 ± 0.665
3.942ValGly: 3.942 ± 1.499
1.819ValHis: 1.819 ± 0.692
3.032ValIle: 3.032 ± 1.664
3.335ValLys: 3.335 ± 1.209
6.064ValLeu: 6.064 ± 1.364
3.639ValMet: 3.639 ± 1.404
5.155ValAsn: 5.155 ± 1.195
3.639ValPro: 3.639 ± 0.849
2.729ValGln: 2.729 ± 1.027
5.458ValArg: 5.458 ± 1.482
3.032ValSer: 3.032 ± 0.674
6.064ValThr: 6.064 ± 1.686
5.155ValVal: 5.155 ± 2.765
0.606ValTrp: 0.606 ± 0.325
5.155ValTyr: 5.155 ± 1.546
0.0ValXaa: 0.0 ± 0.0
Trp
0.606TrpAla: 0.606 ± 0.333
0.0TrpCys: 0.0 ± 0.0
1.213TrpAsp: 1.213 ± 0.363
0.91TrpGlu: 0.91 ± 0.488
0.0TrpPhe: 0.0 ± 0.0
1.516TrpGly: 1.516 ± 0.259
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.606TrpLys: 0.606 ± 0.333
2.122TrpLeu: 2.122 ± 1.362
0.606TrpMet: 0.606 ± 0.325
0.91TrpAsn: 0.91 ± 0.488
1.213TrpPro: 1.213 ± 1.157
0.303TrpGln: 0.303 ± 0.424
0.0TrpArg: 0.0 ± 0.0
1.213TrpSer: 1.213 ± 0.65
0.606TrpThr: 0.606 ± 0.333
1.213TrpVal: 1.213 ± 0.65
0.303TrpTrp: 0.303 ± 0.424
0.303TrpTyr: 0.303 ± 0.424
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.426TyrAla: 2.426 ± 0.726
0.91TyrCys: 0.91 ± 0.488
1.516TyrAsp: 1.516 ± 0.259
1.819TyrGlu: 1.819 ± 1.057
1.213TyrPhe: 1.213 ± 0.363
3.032TyrGly: 3.032 ± 2.312
1.213TyrHis: 1.213 ± 0.666
2.426TyrIle: 2.426 ± 0.472
2.426TyrLys: 2.426 ± 0.873
5.458TyrLeu: 5.458 ± 1.619
2.122TyrMet: 2.122 ± 0.748
1.516TyrAsn: 1.516 ± 0.471
1.213TyrPro: 1.213 ± 1.1
1.516TyrGln: 1.516 ± 0.62
2.729TyrArg: 2.729 ± 1.053
3.032TyrSer: 3.032 ± 0.898
3.639TyrThr: 3.639 ± 0.639
3.032TyrVal: 3.032 ± 1.135
0.91TyrTrp: 0.91 ± 0.308
1.213TyrTyr: 1.213 ± 1.157
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (3299 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski