Amino acid dipepetide frequency for Candidatus Thiodiazotropha endoloripes

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.187AlaAla: 8.187 ± 0.107	1.054AlaCys: 1.054 ± 0.03	5.152AlaAsp: 5.152 ± 0.074	6.489AlaGlu: 6.489 ± 0.087	3.01AlaPhe: 3.01 ± 0.06	6.653AlaGly: 6.653 ± 0.092	1.687AlaHis: 1.687 ± 0.039	5.299AlaIle: 5.299 ± 0.072	3.863AlaLys: 3.863 ± 0.069	9.404AlaLeu: 9.404 ± 0.105	2.559AlaMet: 2.559 ± 0.043	2.88AlaAsn: 2.88 ± 0.053	2.764AlaPro: 2.764 ± 0.051	3.205AlaGln: 3.205 ± 0.046	4.438AlaArg: 4.438 ± 0.065	4.921AlaSer: 4.921 ± 0.069	4.145AlaThr: 4.145 ± 0.075	6.01AlaVal: 6.01 ± 0.071	1.169AlaTrp: 1.169 ± 0.03	2.345AlaTyr: 2.345 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	0.711CysAla: 0.711 ± 0.028	0.154CysCys: 0.154 ± 0.011	0.582CysAsp: 0.582 ± 0.024	0.593CysGlu: 0.593 ± 0.027	0.343CysPhe: 0.343 ± 0.016	0.951CysGly: 0.951 ± 0.026	0.541CysHis: 0.541 ± 0.058	0.477CysIle: 0.477 ± 0.021	0.35CysLys: 0.35 ± 0.015	0.948CysLeu: 0.948 ± 0.028	0.22CysMet: 0.22 ± 0.014	0.354CysAsn: 0.354 ± 0.019	0.558CysPro: 0.558 ± 0.025	0.427CysGln: 0.427 ± 0.017	0.623CysArg: 0.623 ± 0.024	0.621CysSer: 0.621 ± 0.027	0.443CysThr: 0.443 ± 0.02	0.566CysVal: 0.566 ± 0.024	0.124CysTrp: 0.124 ± 0.01	0.297CysTyr: 0.297 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	4.413AspAla: 4.413 ± 0.062	0.579AspCys: 0.579 ± 0.026	3.424AspAsp: 3.424 ± 0.078	4.306AspGlu: 4.306 ± 0.075	2.316AspPhe: 2.316 ± 0.048	4.252AspGly: 4.252 ± 0.077	1.467AspHis: 1.467 ± 0.04	3.285AspIle: 3.285 ± 0.058	2.277AspLys: 2.277 ± 0.049	6.263AspLeu: 6.263 ± 0.076	1.441AspMet: 1.441 ± 0.03	2.074AspAsn: 2.074 ± 0.042	2.976AspPro: 2.976 ± 0.055	3.068AspGln: 3.068 ± 0.055	3.517AspArg: 3.517 ± 0.058	3.381AspSer: 3.381 ± 0.061	2.628AspThr: 2.628 ± 0.05	3.32AspVal: 3.32 ± 0.058	0.925AspTrp: 0.925 ± 0.028	2.158AspTyr: 2.158 ± 0.046	0.0AspXaa: 0.0 ± 0.0
Glu	6.184GluAla: 6.184 ± 0.081	0.453GluCys: 0.453 ± 0.023	3.123GluAsp: 3.123 ± 0.062	4.416GluGlu: 4.416 ± 0.08	2.264GluPhe: 2.264 ± 0.041	3.982GluGly: 3.982 ± 0.064	1.417GluHis: 1.417 ± 0.027	4.499GluIle: 4.499 ± 0.064	3.274GluLys: 3.274 ± 0.059	7.139GluLeu: 7.139 ± 0.092	2.042GluMet: 2.042 ± 0.042	2.383GluAsn: 2.383 ± 0.052	2.406GluPro: 2.406 ± 0.046	3.936GluGln: 3.936 ± 0.065	4.159GluArg: 4.159 ± 0.069	4.481GluSer: 4.481 ± 0.066	3.538GluThr: 3.538 ± 0.052	4.423GluVal: 4.423 ± 0.053	0.869GluTrp: 0.869 ± 0.025	1.657GluTyr: 1.657 ± 0.035	0.0GluXaa: 0.0 ± 0.0
Phe	2.929PheAla: 2.929 ± 0.058	0.419PheCys: 0.419 ± 0.019	2.555PheAsp: 2.555 ± 0.046	2.368PheGlu: 2.368 ± 0.046	1.507PhePhe: 1.507 ± 0.039	2.924PheGly: 2.924 ± 0.055	0.835PheHis: 0.835 ± 0.026	2.225PheIle: 2.225 ± 0.045	1.574PheLys: 1.574 ± 0.036	3.535PheLeu: 3.535 ± 0.065	0.855PheMet: 0.855 ± 0.027	1.548PheAsn: 1.548 ± 0.036	1.504PhePro: 1.504 ± 0.039	1.32PheGln: 1.32 ± 0.034	1.878PheArg: 1.878 ± 0.037	2.928PheSer: 2.928 ± 0.049	2.112PheThr: 2.112 ± 0.043	2.361PheVal: 2.361 ± 0.049	0.519PheTrp: 0.519 ± 0.023	1.216PheTyr: 1.216 ± 0.034	0.0PheXaa: 0.0 ± 0.0
Gly	5.387GlyAla: 5.387 ± 0.075	0.99GlyCys: 0.99 ± 0.031	4.245GlyAsp: 4.245 ± 0.068	5.011GlyGlu: 5.011 ± 0.074	3.223GlyPhe: 3.223 ± 0.051	5.435GlyGly: 5.435 ± 0.099	1.704GlyHis: 1.704 ± 0.039	4.847GlyIle: 4.847 ± 0.071	3.53GlyLys: 3.53 ± 0.066	7.802GlyLeu: 7.802 ± 0.093	2.329GlyMet: 2.329 ± 0.056	2.44GlyAsn: 2.44 ± 0.054	2.103GlyPro: 2.103 ± 0.045	2.746GlyGln: 2.746 ± 0.053	4.139GlyArg: 4.139 ± 0.059	4.603GlySer: 4.603 ± 0.077	3.506GlyThr: 3.506 ± 0.063	5.473GlyVal: 5.473 ± 0.076	1.079GlyTrp: 1.079 ± 0.028	2.647GlyTyr: 2.647 ± 0.06	0.0GlyXaa: 0.0 ± 0.0
His	1.819HisAla: 1.819 ± 0.044	0.303HisCys: 0.303 ± 0.018	1.265HisAsp: 1.265 ± 0.037	1.288HisGlu: 1.288 ± 0.036	0.989HisPhe: 0.989 ± 0.034	1.727HisGly: 1.727 ± 0.041	0.794HisHis: 0.794 ± 0.028	1.27HisIle: 1.27 ± 0.04	0.879HisLys: 0.879 ± 0.029	2.621HisLeu: 2.621 ± 0.051	0.504HisMet: 0.504 ± 0.021	0.889HisAsn: 0.889 ± 0.027	1.355HisPro: 1.355 ± 0.035	1.296HisGln: 1.296 ± 0.031	1.437HisArg: 1.437 ± 0.035	1.33HisSer: 1.33 ± 0.033	1.164HisThr: 1.164 ± 0.036	1.155HisVal: 1.155 ± 0.03	0.384HisTrp: 0.384 ± 0.021	0.907HisTyr: 0.907 ± 0.028	0.0HisXaa: 0.0 ± 0.0
Ile	5.453IleAla: 5.453 ± 0.074	0.6IleCys: 0.6 ± 0.024	4.349IleAsp: 4.349 ± 0.053	4.643IleGlu: 4.643 ± 0.069	1.876IlePhe: 1.876 ± 0.042	4.803IleGly: 4.803 ± 0.07	1.387IleHis: 1.387 ± 0.031	3.184IleIle: 3.184 ± 0.058	2.66IleLys: 2.66 ± 0.054	5.72IleLeu: 5.72 ± 0.072	1.225IleMet: 1.225 ± 0.033	2.641IleAsn: 2.641 ± 0.051	2.996IlePro: 2.996 ± 0.05	2.17IleGln: 2.17 ± 0.045	3.399IleArg: 3.399 ± 0.05	4.257IleSer: 4.257 ± 0.057	3.479IleThr: 3.479 ± 0.061	3.509IleVal: 3.509 ± 0.059	0.682IleTrp: 0.682 ± 0.025	1.638IleTyr: 1.638 ± 0.038	0.0IleXaa: 0.0 ± 0.0
Lys	3.833LysAla: 3.833 ± 0.066	0.281LysCys: 0.281 ± 0.016	2.059LysAsp: 2.059 ± 0.049	2.527LysGlu: 2.527 ± 0.055	1.077LysPhe: 1.077 ± 0.031	2.978LysGly: 2.978 ± 0.062	1.069LysHis: 1.069 ± 0.032	2.487LysIle: 2.487 ± 0.045	2.398LysLys: 2.398 ± 0.07	4.563LysLeu: 4.563 ± 0.073	1.061LysMet: 1.061 ± 0.03	1.493LysAsn: 1.493 ± 0.04	2.353LysPro: 2.353 ± 0.049	2.732LysGln: 2.732 ± 0.055	2.958LysArg: 2.958 ± 0.05	2.792LysSer: 2.792 ± 0.047	2.276LysThr: 2.276 ± 0.044	2.883LysVal: 2.883 ± 0.054	0.437LysTrp: 0.437 ± 0.021	1.0LysTyr: 1.0 ± 0.028	0.0LysXaa: 0.0 ± 0.0
Leu	9.862LeuAla: 9.862 ± 0.106	0.961LeuCys: 0.961 ± 0.031	6.32LeuAsp: 6.32 ± 0.08	6.718LeuGlu: 6.718 ± 0.091	4.506LeuPhe: 4.506 ± 0.079	7.398LeuGly: 7.398 ± 0.083	2.282LeuHis: 2.282 ± 0.046	6.808LeuIle: 6.808 ± 0.085	5.12LeuLys: 5.12 ± 0.065	12.466LeuLeu: 12.466 ± 0.164	2.76LeuMet: 2.76 ± 0.053	4.238LeuAsn: 4.238 ± 0.059	5.207LeuPro: 5.207 ± 0.067	4.882LeuGln: 4.882 ± 0.073	5.592LeuArg: 5.592 ± 0.074	7.805LeuSer: 7.805 ± 0.094	5.62LeuThr: 5.62 ± 0.077	7.114LeuVal: 7.114 ± 0.076	1.163LeuTrp: 1.163 ± 0.037	2.811LeuTyr: 2.811 ± 0.054	0.0LeuXaa: 0.0 ± 0.0
Met	2.503MetAla: 2.503 ± 0.05	0.148MetCys: 0.148 ± 0.01	1.453MetAsp: 1.453 ± 0.032	1.527MetGlu: 1.527 ± 0.034	0.73MetPhe: 0.73 ± 0.024	1.91MetGly: 1.91 ± 0.041	0.528MetHis: 0.528 ± 0.022	1.588MetIle: 1.588 ± 0.032	1.295MetLys: 1.295 ± 0.033	2.849MetLeu: 2.849 ± 0.047	0.759MetMet: 0.759 ± 0.027	1.045MetAsn: 1.045 ± 0.034	1.365MetPro: 1.365 ± 0.039	1.216MetGln: 1.216 ± 0.032	1.482MetArg: 1.482 ± 0.036	1.924MetSer: 1.924 ± 0.047	1.396MetThr: 1.396 ± 0.034	1.912MetVal: 1.912 ± 0.045	0.187MetTrp: 0.187 ± 0.012	0.381MetTyr: 0.381 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	2.734AsnAla: 2.734 ± 0.058	0.415AsnCys: 0.415 ± 0.019	1.934AsnAsp: 1.934 ± 0.047	2.086AsnGlu: 2.086 ± 0.042	1.196AsnPhe: 1.196 ± 0.031	2.661AsnGly: 2.661 ± 0.057	0.973AsnHis: 0.973 ± 0.025	2.141AsnIle: 2.141 ± 0.043	1.511AsnLys: 1.511 ± 0.039	4.109AsnLeu: 4.109 ± 0.066	0.856AsnMet: 0.856 ± 0.026	1.411AsnAsn: 1.411 ± 0.039	2.296AsnPro: 2.296 ± 0.049	1.913AsnGln: 1.913 ± 0.043	2.548AsnArg: 2.548 ± 0.052	2.331AsnSer: 2.331 ± 0.046	1.745AsnThr: 1.745 ± 0.043	1.84AsnVal: 1.84 ± 0.04	0.517AsnTrp: 0.517 ± 0.023	1.119AsnTyr: 1.119 ± 0.027	0.0AsnXaa: 0.0 ± 0.0
Pro	3.647ProAla: 3.647 ± 0.065	0.352ProCys: 0.352 ± 0.016	2.964ProAsp: 2.964 ± 0.047	3.594ProGlu: 3.594 ± 0.064	1.637ProPhe: 1.637 ± 0.041	3.555ProGly: 3.555 ± 0.057	0.903ProHis: 0.903 ± 0.034	2.511ProIle: 2.511 ± 0.04	1.729ProLys: 1.729 ± 0.045	4.639ProLeu: 4.639 ± 0.066	1.192ProMet: 1.192 ± 0.031	1.466ProAsn: 1.466 ± 0.042	1.786ProPro: 1.786 ± 0.038	1.971ProGln: 1.971 ± 0.039	1.795ProArg: 1.795 ± 0.042	2.544ProSer: 2.544 ± 0.046	2.12ProThr: 2.12 ± 0.046	3.627ProVal: 3.627 ± 0.057	0.606ProTrp: 0.606 ± 0.025	1.287ProTyr: 1.287 ± 0.04	0.0ProXaa: 0.0 ± 0.0
Gln	4.723GlnAla: 4.723 ± 0.068	0.328GlnCys: 0.328 ± 0.016	1.998GlnAsp: 1.998 ± 0.043	2.627GlnGlu: 2.627 ± 0.054	1.47GlnPhe: 1.47 ± 0.035	3.273GlnGly: 3.273 ± 0.057	1.187GlnHis: 1.187 ± 0.027	2.731GlnIle: 2.731 ± 0.045	1.647GlnLys: 1.647 ± 0.041	5.377GlnLeu: 5.377 ± 0.072	1.153GlnMet: 1.153 ± 0.034	1.411GlnAsn: 1.411 ± 0.037	2.165GlnPro: 2.165 ± 0.05	3.594GlnGln: 3.594 ± 0.085	3.043GlnArg: 3.043 ± 0.055	2.947GlnSer: 2.947 ± 0.055	2.225GlnThr: 2.225 ± 0.046	3.21GlnVal: 3.21 ± 0.054	0.575GlnTrp: 0.575 ± 0.027	0.956GlnTyr: 0.956 ± 0.03	0.0GlnXaa: 0.0 ± 0.0
Arg	3.967ArgAla: 3.967 ± 0.059	0.528ArgCys: 0.528 ± 0.02	3.121ArgAsp: 3.121 ± 0.051	3.825ArgGlu: 3.825 ± 0.054	2.702ArgPhe: 2.702 ± 0.044	3.314ArgGly: 3.314 ± 0.061	1.48ArgHis: 1.48 ± 0.041	3.859ArgIle: 3.859 ± 0.051	2.583ArgLys: 2.583 ± 0.048	7.029ArgLeu: 7.029 ± 0.086	1.535ArgMet: 1.535 ± 0.035	2.119ArgAsn: 2.119 ± 0.039	2.124ArgPro: 2.124 ± 0.044	3.05ArgGln: 3.05 ± 0.052	3.436ArgArg: 3.436 ± 0.065	3.281ArgSer: 3.281 ± 0.054	2.4ArgThr: 2.4 ± 0.044	3.879ArgVal: 3.879 ± 0.062	0.822ArgTrp: 0.822 ± 0.021	2.066ArgTyr: 2.066 ± 0.042	0.0ArgXaa: 0.0 ± 0.0
Ser	5.405SerAla: 5.405 ± 0.066	0.691SerCys: 0.691 ± 0.033	3.852SerAsp: 3.852 ± 0.067	4.201SerGlu: 4.201 ± 0.062	2.403SerPhe: 2.403 ± 0.045	5.813SerGly: 5.813 ± 0.083	1.562SerHis: 1.562 ± 0.037	3.704SerIle: 3.704 ± 0.056	2.571SerLys: 2.571 ± 0.043	7.241SerLeu: 7.241 ± 0.102	1.756SerMet: 1.756 ± 0.039	2.301SerAsn: 2.301 ± 0.05	2.535SerPro: 2.535 ± 0.047	2.644SerGln: 2.644 ± 0.046	3.757SerArg: 3.757 ± 0.05	4.097SerSer: 4.097 ± 0.079	2.95SerThr: 2.95 ± 0.057	4.161SerVal: 4.161 ± 0.062	0.856SerTrp: 0.856 ± 0.032	1.81SerTyr: 1.81 ± 0.045	0.0SerXaa: 0.0 ± 0.0
Thr	4.462ThrAla: 4.462 ± 0.076	0.477ThrCys: 0.477 ± 0.023	3.093ThrAsp: 3.093 ± 0.059	3.314ThrGlu: 3.314 ± 0.048	1.692ThrPhe: 1.692 ± 0.041	4.289ThrGly: 4.289 ± 0.062	1.16ThrHis: 1.16 ± 0.029	3.176ThrIle: 3.176 ± 0.056	1.688ThrLys: 1.688 ± 0.044	6.184ThrLeu: 6.184 ± 0.085	1.072ThrMet: 1.072 ± 0.028	1.634ThrAsn: 1.634 ± 0.038	2.817ThrPro: 2.817 ± 0.051	1.953ThrGln: 1.953 ± 0.037	2.572ThrArg: 2.572 ± 0.042	2.936ThrSer: 2.936 ± 0.058	2.88ThrThr: 2.88 ± 0.063	3.274ThrVal: 3.274 ± 0.06	0.521ThrTrp: 0.521 ± 0.021	1.241ThrTyr: 1.241 ± 0.034	0.0ThrXaa: 0.0 ± 0.0
Val	6.031ValAla: 6.031 ± 0.077	0.679ValCys: 0.679 ± 0.023	4.278ValAsp: 4.278 ± 0.061	4.873ValGlu: 4.873 ± 0.07	2.414ValPhe: 2.414 ± 0.045	4.4ValGly: 4.4 ± 0.064	1.263ValHis: 1.263 ± 0.035	4.455ValIle: 4.455 ± 0.06	2.818ValLys: 2.818 ± 0.047	6.433ValLeu: 6.433 ± 0.086	1.927ValMet: 1.927 ± 0.041	2.568ValAsn: 2.568 ± 0.048	2.668ValPro: 2.668 ± 0.056	1.979ValGln: 1.979 ± 0.041	3.402ValArg: 3.402 ± 0.059	4.538ValSer: 4.538 ± 0.062	3.882ValThr: 3.882 ± 0.065	5.357ValVal: 5.357 ± 0.084	0.777ValTrp: 0.777 ± 0.027	1.733ValTyr: 1.733 ± 0.038	0.0ValXaa: 0.0 ± 0.0
Trp	0.767TrpAla: 0.767 ± 0.027	0.147TrpCys: 0.147 ± 0.011	0.617TrpAsp: 0.617 ± 0.023	0.674TrpGlu: 0.674 ± 0.024	0.587TrpPhe: 0.587 ± 0.023	0.843TrpGly: 0.843 ± 0.026	0.391TrpHis: 0.391 ± 0.018	0.731TrpIle: 0.731 ± 0.027	0.47TrpLys: 0.47 ± 0.018	1.798TrpLeu: 1.798 ± 0.047	0.356TrpMet: 0.356 ± 0.017	0.454TrpAsn: 0.454 ± 0.019	0.506TrpPro: 0.506 ± 0.021	0.889TrpGln: 0.889 ± 0.032	0.862TrpArg: 0.862 ± 0.025	0.859TrpSer: 0.859 ± 0.027	0.485TrpThr: 0.485 ± 0.019	0.863TrpVal: 0.863 ± 0.025	0.189TrpTrp: 0.189 ± 0.012	0.365TrpTyr: 0.365 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.216TyrAla: 2.216 ± 0.044	0.321TyrCys: 0.321 ± 0.018	1.686TyrAsp: 1.686 ± 0.045	1.564TyrGlu: 1.564 ± 0.036	1.17TyrPhe: 1.17 ± 0.032	2.077TyrGly: 2.077 ± 0.045	0.747TyrHis: 0.747 ± 0.023	1.395TyrIle: 1.395 ± 0.033	1.022TyrLys: 1.022 ± 0.03	3.514TyrLeu: 3.514 ± 0.06	0.599TyrMet: 0.599 ± 0.024	0.988TyrAsn: 0.988 ± 0.027	1.442TyrPro: 1.442 ± 0.038	1.65TyrGln: 1.65 ± 0.034	2.084TyrArg: 2.084 ± 0.047	1.734TyrSer: 1.734 ± 0.035	1.437TyrThr: 1.437 ± 0.042	1.538TyrVal: 1.538 ± 0.029	0.45TyrTrp: 0.45 ± 0.019	0.948TyrTyr: 0.948 ± 0.032	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3951 proteins (1269643 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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