Amino acid dipepetide frequency for Rhinolophus ferrumequinum papillomavirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.384AlaAla: 4.384 ± 2.597
1.315AlaCys: 1.315 ± 0.922
2.63AlaAsp: 2.63 ± 0.959
6.138AlaGlu: 6.138 ± 1.126
2.192AlaPhe: 2.192 ± 0.725
3.946AlaGly: 3.946 ± 0.886
0.438AlaHis: 0.438 ± 0.328
3.069AlaIle: 3.069 ± 1.233
2.63AlaLys: 2.63 ± 0.939
2.63AlaLeu: 2.63 ± 0.98
0.877AlaMet: 0.877 ± 0.405
2.63AlaAsn: 2.63 ± 0.808
2.63AlaPro: 2.63 ± 0.517
2.192AlaGln: 2.192 ± 0.795
6.138AlaArg: 6.138 ± 1.401
5.699AlaSer: 5.699 ± 1.639
3.069AlaThr: 3.069 ± 0.794
7.014AlaVal: 7.014 ± 1.732
0.877AlaTrp: 0.877 ± 0.657
1.315AlaTyr: 1.315 ± 0.751
0.0AlaXaa: 0.0 ± 0.0
Cys
1.315CysAla: 1.315 ± 0.86
1.315CysCys: 1.315 ± 1.016
1.315CysAsp: 1.315 ± 0.86
0.877CysGlu: 0.877 ± 0.657
1.754CysPhe: 1.754 ± 0.94
0.877CysGly: 0.877 ± 0.641
0.0CysHis: 0.0 ± 0.0
0.438CysIle: 0.438 ± 0.423
2.63CysLys: 2.63 ± 0.918
1.754CysLeu: 1.754 ± 1.029
0.877CysMet: 0.877 ± 0.657
0.0CysAsn: 0.0 ± 0.0
1.315CysPro: 1.315 ± 0.756
1.315CysGln: 1.315 ± 0.746
0.438CysArg: 0.438 ± 0.423
0.877CysSer: 0.877 ± 0.657
0.877CysThr: 0.877 ± 0.657
1.315CysVal: 1.315 ± 1.185
0.0CysTrp: 0.0 ± 0.0
0.877CysTyr: 0.877 ± 0.657
0.0CysXaa: 0.0 ± 0.0
Asp
3.069AspAla: 3.069 ± 0.611
0.877AspCys: 0.877 ± 0.405
4.822AspAsp: 4.822 ± 1.089
3.069AspGlu: 3.069 ± 0.824
4.384AspPhe: 4.384 ± 0.717
5.261AspGly: 5.261 ± 2.004
0.877AspHis: 0.877 ± 0.657
3.946AspIle: 3.946 ± 1.504
2.63AspLys: 2.63 ± 0.644
2.63AspLeu: 2.63 ± 1.134
0.877AspMet: 0.877 ± 0.761
3.069AspAsn: 3.069 ± 1.279
7.014AspPro: 7.014 ± 2.438
1.754AspGln: 1.754 ± 0.662
1.315AspArg: 1.315 ± 0.427
6.576AspSer: 6.576 ± 1.363
4.384AspThr: 4.384 ± 0.477
5.699AspVal: 5.699 ± 0.836
0.438AspTrp: 0.438 ± 0.437
0.438AspTyr: 0.438 ± 0.419
0.0AspXaa: 0.0 ± 0.0
Glu
5.261GluAla: 5.261 ± 1.148
1.315GluCys: 1.315 ± 0.985
5.699GluAsp: 5.699 ± 2.291
5.261GluGlu: 5.261 ± 2.581
2.63GluPhe: 2.63 ± 1.076
1.754GluGly: 1.754 ± 0.651
2.192GluHis: 2.192 ± 0.704
1.754GluIle: 1.754 ± 0.786
1.754GluLys: 1.754 ± 0.7
6.138GluLeu: 6.138 ± 1.539
1.315GluMet: 1.315 ± 0.482
3.507GluAsn: 3.507 ± 1.097
3.946GluPro: 3.946 ± 0.544
4.822GluGln: 4.822 ± 1.07
2.63GluArg: 2.63 ± 0.644
3.946GluSer: 3.946 ± 1.3
3.507GluThr: 3.507 ± 1.158
3.507GluVal: 3.507 ± 1.671
0.877GluTrp: 0.877 ± 0.495
3.069GluTyr: 3.069 ± 1.083
0.0GluXaa: 0.0 ± 0.0
Phe
4.384PheAla: 4.384 ± 0.392
0.438PheCys: 0.438 ± 0.328
1.315PheAsp: 1.315 ± 0.714
4.384PheGlu: 4.384 ± 2.611
0.877PhePhe: 0.877 ± 0.405
3.069PheGly: 3.069 ± 0.912
0.438PheHis: 0.438 ± 0.328
2.63PheIle: 2.63 ± 0.918
0.438PheLys: 0.438 ± 0.437
5.699PheLeu: 5.699 ± 1.204
1.315PheMet: 1.315 ± 0.779
3.069PheAsn: 3.069 ± 1.26
3.069PhePro: 3.069 ± 0.412
2.63PheGln: 2.63 ± 0.842
2.63PheArg: 2.63 ± 0.63
1.315PheSer: 1.315 ± 0.92
1.754PheThr: 1.754 ± 0.579
2.192PheVal: 2.192 ± 1.306
1.754PheTrp: 1.754 ± 0.922
3.507PheTyr: 3.507 ± 1.539
0.0PheXaa: 0.0 ± 0.0
Gly
4.822GlyAla: 4.822 ± 1.773
0.877GlyCys: 0.877 ± 0.405
4.384GlyAsp: 4.384 ± 1.505
3.507GlyGlu: 3.507 ± 1.347
2.192GlyPhe: 2.192 ± 0.451
5.261GlyGly: 5.261 ± 2.562
1.315GlyHis: 1.315 ± 1.141
3.507GlyIle: 3.507 ± 0.646
1.315GlyLys: 1.315 ± 0.714
3.946GlyLeu: 3.946 ± 1.293
0.877GlyMet: 0.877 ± 0.591
2.192GlyAsn: 2.192 ± 0.927
3.069GlyPro: 3.069 ± 1.486
3.946GlyGln: 3.946 ± 0.982
6.138GlyArg: 6.138 ± 1.972
7.891GlySer: 7.891 ± 2.105
4.384GlyThr: 4.384 ± 0.736
4.384GlyVal: 4.384 ± 0.593
0.877GlyTrp: 0.877 ± 0.657
0.438GlyTyr: 0.438 ± 0.328
0.0GlyXaa: 0.0 ± 0.0
His
2.192HisAla: 2.192 ± 0.741
0.0HisCys: 0.0 ± 0.0
1.754HisAsp: 1.754 ± 0.72
0.877HisGlu: 0.877 ± 0.699
1.315HisPhe: 1.315 ± 0.587
1.315HisGly: 1.315 ± 1.172
0.877HisHis: 0.877 ± 0.664
1.315HisIle: 1.315 ± 0.629
0.877HisLys: 0.877 ± 0.519
0.877HisLeu: 0.877 ± 0.405
0.438HisMet: 0.438 ± 0.437
1.315HisAsn: 1.315 ± 0.414
2.192HisPro: 2.192 ± 0.765
0.877HisGln: 0.877 ± 0.519
1.315HisArg: 1.315 ± 0.343
0.877HisSer: 0.877 ± 0.405
1.315HisThr: 1.315 ± 0.756
1.315HisVal: 1.315 ± 0.815
0.877HisTrp: 0.877 ± 0.405
0.438HisTyr: 0.438 ± 0.328
0.0HisXaa: 0.0 ± 0.0
Ile
2.192IleAla: 2.192 ± 0.839
0.877IleCys: 0.877 ± 0.613
5.261IleAsp: 5.261 ± 1.505
2.63IleGlu: 2.63 ± 1.289
1.754IlePhe: 1.754 ± 0.657
3.507IleGly: 3.507 ± 1.527
1.754IleHis: 1.754 ± 0.61
1.315IleIle: 1.315 ± 0.629
3.069IleLys: 3.069 ± 1.051
2.63IleLeu: 2.63 ± 1.845
0.0IleMet: 0.0 ± 0.0
0.0IleAsn: 0.0 ± 0.0
2.192IlePro: 2.192 ± 1.546
1.754IleGln: 1.754 ± 0.957
2.63IleArg: 2.63 ± 1.443
1.754IleSer: 1.754 ± 0.76
5.261IleThr: 5.261 ± 0.838
3.069IleVal: 3.069 ± 0.979
0.0IleTrp: 0.0 ± 0.0
0.877IleTyr: 0.877 ± 0.473
0.0IleXaa: 0.0 ± 0.0
Lys
3.069LysAla: 3.069 ± 0.878
1.754LysCys: 1.754 ± 0.662
3.507LysAsp: 3.507 ± 1.414
1.754LysGlu: 1.754 ± 0.695
5.261LysPhe: 5.261 ± 1.696
2.63LysGly: 2.63 ± 1.019
0.438LysHis: 0.438 ± 0.328
0.438LysIle: 0.438 ± 0.423
3.946LysLys: 3.946 ± 1.55
2.192LysLeu: 2.192 ± 0.819
1.315LysMet: 1.315 ± 0.632
2.63LysAsn: 2.63 ± 1.171
1.315LysPro: 1.315 ± 0.714
2.192LysGln: 2.192 ± 0.775
3.507LysArg: 3.507 ± 0.447
2.192LysSer: 2.192 ± 1.249
2.192LysThr: 2.192 ± 0.704
3.507LysVal: 3.507 ± 0.612
0.438LysTrp: 0.438 ± 0.38
0.877LysTyr: 0.877 ± 0.478
0.0LysXaa: 0.0 ± 0.0
Leu
5.699LeuAla: 5.699 ± 0.587
1.754LeuCys: 1.754 ± 0.732
4.822LeuAsp: 4.822 ± 0.684
3.946LeuGlu: 3.946 ± 0.681
4.822LeuPhe: 4.822 ± 0.898
6.138LeuGly: 6.138 ± 1.222
2.63LeuHis: 2.63 ± 0.539
2.192LeuIle: 2.192 ± 1.03
5.699LeuLys: 5.699 ± 2.116
7.014LeuLeu: 7.014 ± 2.494
2.192LeuMet: 2.192 ± 0.948
2.192LeuAsn: 2.192 ± 0.351
2.63LeuPro: 2.63 ± 0.528
5.699LeuGln: 5.699 ± 1.734
6.576LeuArg: 6.576 ± 2.478
6.576LeuSer: 6.576 ± 1.161
5.261LeuThr: 5.261 ± 1.792
3.507LeuVal: 3.507 ± 1.533
0.438LeuTrp: 0.438 ± 0.38
3.069LeuTyr: 3.069 ± 1.285
0.0LeuXaa: 0.0 ± 0.0
Met
1.754MetAla: 1.754 ± 0.798
1.315MetCys: 1.315 ± 0.632
1.754MetAsp: 1.754 ± 0.662
0.877MetGlu: 0.877 ± 0.874
0.877MetPhe: 0.877 ± 0.564
0.438MetGly: 0.438 ± 0.38
0.438MetHis: 0.438 ± 0.437
1.315MetIle: 1.315 ± 0.343
0.438MetLys: 0.438 ± 0.38
3.069MetLeu: 3.069 ± 1.352
0.0MetMet: 0.0 ± 0.0
0.877MetAsn: 0.877 ± 0.761
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
0.438MetArg: 0.438 ± 0.55
2.63MetSer: 2.63 ± 1.223
0.877MetThr: 0.877 ± 0.405
2.63MetVal: 2.63 ± 0.84
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
0.877AsnAla: 0.877 ± 0.657
0.0AsnCys: 0.0 ± 0.0
2.63AsnAsp: 2.63 ± 0.63
3.069AsnGlu: 3.069 ± 0.952
1.315AsnPhe: 1.315 ± 0.632
1.754AsnGly: 1.754 ± 0.909
0.877AsnHis: 0.877 ± 0.39
2.63AsnIle: 2.63 ± 0.727
2.63AsnLys: 2.63 ± 0.435
1.315AsnLeu: 1.315 ± 0.763
0.877AsnMet: 0.877 ± 0.519
2.192AsnAsn: 2.192 ± 1.012
2.63AsnPro: 2.63 ± 0.685
1.754AsnGln: 1.754 ± 0.922
2.63AsnArg: 2.63 ± 1.039
3.507AsnSer: 3.507 ± 1.226
3.069AsnThr: 3.069 ± 0.936
2.63AsnVal: 2.63 ± 1.119
0.438AsnTrp: 0.438 ± 0.423
0.877AsnTyr: 0.877 ± 0.761
0.0AsnXaa: 0.0 ± 0.0
Pro
3.946ProAla: 3.946 ± 2.223
0.877ProCys: 0.877 ± 0.495
3.069ProAsp: 3.069 ± 1.18
9.645ProGlu: 9.645 ± 3.133
1.754ProPhe: 1.754 ± 0.85
3.069ProGly: 3.069 ± 1.256
0.877ProHis: 0.877 ± 0.478
2.63ProIle: 2.63 ± 0.864
2.192ProLys: 2.192 ± 1.012
4.822ProLeu: 4.822 ± 1.195
1.315ProMet: 1.315 ± 0.74
1.315ProAsn: 1.315 ± 0.756
6.138ProPro: 6.138 ± 1.756
2.192ProGln: 2.192 ± 0.45
3.069ProArg: 3.069 ± 1.023
6.138ProSer: 6.138 ± 3.141
3.507ProThr: 3.507 ± 1.067
2.63ProVal: 2.63 ± 0.764
0.438ProTrp: 0.438 ± 0.437
2.63ProTyr: 2.63 ± 1.264
0.0ProXaa: 0.0 ± 0.0
Gln
3.069GlnAla: 3.069 ± 1.118
0.438GlnCys: 0.438 ± 0.328
1.754GlnAsp: 1.754 ± 0.826
2.192GlnGlu: 2.192 ± 1.293
2.192GlnPhe: 2.192 ± 0.351
2.63GlnGly: 2.63 ± 1.223
1.315GlnHis: 1.315 ± 0.593
1.315GlnIle: 1.315 ± 0.427
0.877GlnLys: 0.877 ± 0.39
7.891GlnLeu: 7.891 ± 2.276
0.877GlnMet: 0.877 ± 0.498
1.754GlnAsn: 1.754 ± 0.689
2.192GlnPro: 2.192 ± 0.765
2.192GlnGln: 2.192 ± 0.941
3.507GlnArg: 3.507 ± 2.104
3.069GlnSer: 3.069 ± 0.811
3.507GlnThr: 3.507 ± 1.19
2.192GlnVal: 2.192 ± 1.244
0.877GlnTrp: 0.877 ± 0.519
1.315GlnTyr: 1.315 ± 0.815
0.0GlnXaa: 0.0 ± 0.0
Arg
4.822ArgAla: 4.822 ± 1.092
2.192ArgCys: 2.192 ± 1.408
3.946ArgAsp: 3.946 ± 0.793
2.192ArgGlu: 2.192 ± 0.591
3.507ArgPhe: 3.507 ± 1.523
5.699ArgGly: 5.699 ± 0.868
2.192ArgHis: 2.192 ± 0.916
1.754ArgIle: 1.754 ± 0.205
4.822ArgLys: 4.822 ± 1.19
4.822ArgLeu: 4.822 ± 1.789
0.438ArgMet: 0.438 ± 0.38
0.438ArgAsn: 0.438 ± 0.423
4.384ArgPro: 4.384 ± 3.29
1.754ArgGln: 1.754 ± 1.328
7.891ArgArg: 7.891 ± 3.275
5.699ArgSer: 5.699 ± 1.686
4.384ArgThr: 4.384 ± 0.902
6.138ArgVal: 6.138 ± 1.401
0.0ArgTrp: 0.0 ± 0.0
1.315ArgTyr: 1.315 ± 0.482
0.0ArgXaa: 0.0 ± 0.0
Ser
3.507SerAla: 3.507 ± 0.826
0.877SerCys: 0.877 ± 0.495
3.946SerAsp: 3.946 ± 0.617
3.946SerGlu: 3.946 ± 1.844
3.507SerPhe: 3.507 ± 0.761
7.014SerGly: 7.014 ± 1.794
1.315SerHis: 1.315 ± 0.674
4.822SerIle: 4.822 ± 1.315
1.315SerLys: 1.315 ± 0.751
8.33SerLeu: 8.33 ± 2.162
2.192SerMet: 2.192 ± 0.731
3.946SerAsn: 3.946 ± 0.872
3.069SerPro: 3.069 ± 1.918
1.315SerGln: 1.315 ± 0.587
5.699SerArg: 5.699 ± 1.796
7.014SerSer: 7.014 ± 1.212
4.822SerThr: 4.822 ± 1.828
6.576SerVal: 6.576 ± 1.196
0.877SerTrp: 0.877 ± 0.519
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
2.63ThrAla: 2.63 ± 0.828
1.315ThrCys: 1.315 ± 0.92
5.699ThrAsp: 5.699 ± 0.716
4.822ThrGlu: 4.822 ± 0.91
2.192ThrPhe: 2.192 ± 1.014
3.946ThrGly: 3.946 ± 1.077
0.877ThrHis: 0.877 ± 0.687
1.315ThrIle: 1.315 ± 0.996
1.315ThrLys: 1.315 ± 0.756
6.138ThrLeu: 6.138 ± 1.764
1.315ThrMet: 1.315 ± 0.632
2.63ThrAsn: 2.63 ± 0.787
6.576ThrPro: 6.576 ± 1.117
3.069ThrGln: 3.069 ± 0.774
6.576ThrArg: 6.576 ± 1.48
2.192ThrSer: 2.192 ± 0.845
3.946ThrThr: 3.946 ± 0.967
5.699ThrVal: 5.699 ± 1.274
0.438ThrTrp: 0.438 ± 0.437
1.315ThrTyr: 1.315 ± 0.482
0.0ThrXaa: 0.0 ± 0.0
Val
2.63ValAla: 2.63 ± 0.685
0.877ValCys: 0.877 ± 1.101
3.069ValAsp: 3.069 ± 0.858
3.507ValGlu: 3.507 ± 1.527
3.507ValPhe: 3.507 ± 0.987
3.069ValGly: 3.069 ± 0.858
1.754ValHis: 1.754 ± 1.365
3.946ValIle: 3.946 ± 0.772
3.507ValLys: 3.507 ± 0.8
5.699ValLeu: 5.699 ± 1.442
1.315ValMet: 1.315 ± 0.619
2.63ValAsn: 2.63 ± 1.086
6.576ValPro: 6.576 ± 1.068
4.822ValGln: 4.822 ± 1.146
3.069ValArg: 3.069 ± 0.693
5.261ValSer: 5.261 ± 0.896
4.822ValThr: 4.822 ± 1.43
4.822ValVal: 4.822 ± 1.886
1.315ValTrp: 1.315 ± 0.865
5.261ValTyr: 5.261 ± 2.398
0.0ValXaa: 0.0 ± 0.0
Trp
0.877TrpAla: 0.877 ± 0.405
0.877TrpCys: 0.877 ± 0.657
0.438TrpAsp: 0.438 ± 0.423
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
1.315TrpGly: 1.315 ± 0.482
0.877TrpHis: 0.877 ± 0.492
0.438TrpIle: 0.438 ± 0.328
1.315TrpLys: 1.315 ± 0.726
1.754TrpLeu: 1.754 ± 0.798
0.438TrpMet: 0.438 ± 0.38
0.438TrpAsn: 0.438 ± 0.437
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.438TrpArg: 0.438 ± 0.437
0.0TrpSer: 0.0 ± 0.0
1.754TrpThr: 1.754 ± 1.039
0.877TrpVal: 0.877 ± 0.405
0.0TrpTrp: 0.0 ± 0.0
0.438TrpTyr: 0.438 ± 0.328
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.315TyrAla: 1.315 ± 0.714
0.877TyrCys: 0.877 ± 0.58
1.315TyrAsp: 1.315 ± 0.482
2.192TyrGlu: 2.192 ± 1.088
0.877TyrPhe: 0.877 ± 0.761
3.069TyrGly: 3.069 ± 0.831
0.877TyrHis: 0.877 ± 0.478
1.754TyrIle: 1.754 ± 0.205
1.754TyrLys: 1.754 ± 0.922
3.507TyrLeu: 3.507 ± 0.382
0.438TyrMet: 0.438 ± 0.378
0.877TyrAsn: 0.877 ± 0.492
1.315TyrPro: 1.315 ± 0.815
0.877TyrGln: 0.877 ± 0.58
1.754TyrArg: 1.754 ± 0.61
0.877TyrSer: 0.877 ± 0.874
1.315TyrThr: 1.315 ± 0.815
1.754TyrVal: 1.754 ± 0.72
1.315TyrTrp: 1.315 ± 0.482
1.754TyrTyr: 1.754 ± 1.211
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2282 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski