Amino acid dipepetide frequency for CRESS virus sp. ctBNR11

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.861AlaAla: 3.861 ± 0.284
0.0AlaCys: 0.0 ± 0.0
0.0AlaAsp: 0.0 ± 0.0
5.792AlaGlu: 5.792 ± 0.865
0.0AlaPhe: 0.0 ± 0.0
3.861AlaGly: 3.861 ± 2.866
3.861AlaHis: 3.861 ± 0.284
1.931AlaIle: 1.931 ± 1.149
1.931AlaLys: 1.931 ± 1.433
3.861AlaLeu: 3.861 ± 0.284
0.0AlaMet: 0.0 ± 0.0
0.0AlaAsn: 0.0 ± 0.0
0.0AlaPro: 0.0 ± 0.0
1.931AlaGln: 1.931 ± 1.433
3.861AlaArg: 3.861 ± 2.866
1.931AlaSer: 1.931 ± 1.433
1.931AlaThr: 1.931 ± 1.149
1.931AlaVal: 1.931 ± 1.433
1.931AlaTrp: 1.931 ± 1.149
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.931CysAla: 1.931 ± 1.149
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.931CysGlu: 1.931 ± 1.149
1.931CysPhe: 1.931 ± 1.149
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
1.931CysAsn: 1.931 ± 1.149
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
5.792CysArg: 5.792 ± 3.447
1.931CysSer: 1.931 ± 1.149
0.0CysThr: 0.0 ± 0.0
1.931CysVal: 1.931 ± 1.433
0.0CysTrp: 0.0 ± 0.0
1.931CysTyr: 1.931 ± 1.149
0.0CysXaa: 0.0 ± 0.0
Asp
0.0AspAla: 0.0 ± 0.0
1.931AspCys: 1.931 ± 1.149
3.861AspAsp: 3.861 ± 2.866
3.861AspGlu: 3.861 ± 2.298
3.861AspPhe: 3.861 ± 0.284
1.931AspGly: 1.931 ± 1.433
0.0AspHis: 0.0 ± 0.0
3.861AspIle: 3.861 ± 2.298
5.792AspLys: 5.792 ± 0.865
1.931AspLeu: 1.931 ± 1.149
3.861AspMet: 3.861 ± 0.284
7.722AspAsn: 7.722 ± 0.568
3.861AspPro: 3.861 ± 2.866
0.0AspGln: 0.0 ± 0.0
7.722AspArg: 7.722 ± 4.596
0.0AspSer: 0.0 ± 0.0
3.861AspThr: 3.861 ± 0.284
3.861AspVal: 3.861 ± 0.284
0.0AspTrp: 0.0 ± 0.0
5.792AspTyr: 5.792 ± 0.865
0.0AspXaa: 0.0 ± 0.0
Glu
0.0GluAla: 0.0 ± 0.0
0.0GluCys: 0.0 ± 0.0
9.653GluAsp: 9.653 ± 0.581
1.931GluGlu: 1.931 ± 1.149
0.0GluPhe: 0.0 ± 0.0
3.861GluGly: 3.861 ± 2.298
0.0GluHis: 0.0 ± 0.0
3.861GluIle: 3.861 ± 2.298
7.722GluLys: 7.722 ± 4.596
3.861GluLeu: 3.861 ± 2.298
0.0GluMet: 0.0 ± 0.0
5.792GluAsn: 5.792 ± 3.447
1.931GluPro: 1.931 ± 1.149
0.0GluGln: 0.0 ± 0.0
0.0GluArg: 0.0 ± 0.0
1.931GluSer: 1.931 ± 1.149
3.861GluThr: 3.861 ± 2.298
0.0GluVal: 0.0 ± 0.0
1.931GluTrp: 1.931 ± 1.433
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
1.931PheAla: 1.931 ± 1.433
0.0PheCys: 0.0 ± 0.0
3.861PheAsp: 3.861 ± 2.298
0.0PheGlu: 0.0 ± 0.0
3.861PhePhe: 3.861 ± 0.284
1.931PheGly: 1.931 ± 1.433
0.0PheHis: 0.0 ± 0.0
1.931PheIle: 1.931 ± 1.149
5.792PheLys: 5.792 ± 1.717
0.0PheLeu: 0.0 ± 0.0
1.931PheMet: 1.931 ± 1.433
1.931PheAsn: 1.931 ± 1.433
0.0PhePro: 0.0 ± 0.0
5.792PheGln: 5.792 ± 3.447
1.931PheArg: 1.931 ± 1.433
9.653PheSer: 9.653 ± 0.581
1.931PheThr: 1.931 ± 1.149
1.931PheVal: 1.931 ± 1.433
1.931PheTrp: 1.931 ± 1.149
1.931PheTyr: 1.931 ± 1.433
0.0PheXaa: 0.0 ± 0.0
Gly
5.792GlyAla: 5.792 ± 4.299
0.0GlyCys: 0.0 ± 0.0
0.0GlyAsp: 0.0 ± 0.0
1.931GlyGlu: 1.931 ± 1.149
1.931GlyPhe: 1.931 ± 1.433
5.792GlyGly: 5.792 ± 1.717
0.0GlyHis: 0.0 ± 0.0
0.0GlyIle: 0.0 ± 0.0
9.653GlyLys: 9.653 ± 3.163
3.861GlyLeu: 3.861 ± 2.866
3.861GlyMet: 3.861 ± 0.284
7.722GlyAsn: 7.722 ± 0.568
1.931GlyPro: 1.931 ± 1.149
0.0GlyGln: 0.0 ± 0.0
1.931GlyArg: 1.931 ± 1.433
1.931GlySer: 1.931 ± 1.149
9.653GlyThr: 9.653 ± 0.581
3.861GlyVal: 3.861 ± 2.298
1.931GlyTrp: 1.931 ± 1.433
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.931HisGlu: 1.931 ± 1.149
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
1.931HisIle: 1.931 ± 1.149
1.931HisLys: 1.931 ± 1.433
1.931HisLeu: 1.931 ± 1.149
1.931HisMet: 1.931 ± 1.433
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
3.861HisSer: 3.861 ± 2.866
0.0HisThr: 0.0 ± 0.0
1.931HisVal: 1.931 ± 1.149
1.931HisTrp: 1.931 ± 1.149
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.931IleAla: 1.931 ± 1.433
1.931IleCys: 1.931 ± 1.149
5.792IleAsp: 5.792 ± 1.717
5.792IleGlu: 5.792 ± 3.447
5.792IlePhe: 5.792 ± 0.865
3.861IleGly: 3.861 ± 0.284
3.861IleHis: 3.861 ± 2.298
7.722IleIle: 7.722 ± 2.014
7.722IleLys: 7.722 ± 4.596
5.792IleLeu: 5.792 ± 0.865
1.931IleMet: 1.931 ± 1.149
3.861IleAsn: 3.861 ± 0.284
0.0IlePro: 0.0 ± 0.0
0.0IleGln: 0.0 ± 0.0
0.0IleArg: 0.0 ± 0.0
0.0IleSer: 0.0 ± 0.0
1.931IleThr: 1.931 ± 1.433
7.722IleVal: 7.722 ± 0.568
0.0IleTrp: 0.0 ± 0.0
3.861IleTyr: 3.861 ± 2.298
0.0IleXaa: 0.0 ± 0.0
Lys
3.861LysAla: 3.861 ± 0.284
1.931LysCys: 1.931 ± 1.149
11.583LysAsp: 11.583 ± 4.312
7.722LysGlu: 7.722 ± 4.596
3.861LysPhe: 3.861 ± 2.866
5.792LysGly: 5.792 ± 0.865
0.0LysHis: 0.0 ± 0.0
3.861LysIle: 3.861 ± 2.298
3.861LysLys: 3.861 ± 0.284
3.861LysLeu: 3.861 ± 2.298
0.0LysMet: 0.0 ± 0.0
7.722LysAsn: 7.722 ± 0.568
7.722LysPro: 7.722 ± 0.568
3.861LysGln: 3.861 ± 2.866
3.861LysArg: 3.861 ± 0.284
7.722LysSer: 7.722 ± 0.568
7.722LysThr: 7.722 ± 0.568
7.722LysVal: 7.722 ± 2.014
3.861LysTrp: 3.861 ± 2.866
7.722LysTyr: 7.722 ± 0.568
0.0LysXaa: 0.0 ± 0.0
Leu
1.931LeuAla: 1.931 ± 1.433
0.0LeuCys: 0.0 ± 0.0
5.792LeuAsp: 5.792 ± 1.717
1.931LeuGlu: 1.931 ± 1.149
0.0LeuPhe: 0.0 ± 0.0
3.861LeuGly: 3.861 ± 0.284
0.0LeuHis: 0.0 ± 0.0
1.931LeuIle: 1.931 ± 1.433
11.583LeuLys: 11.583 ± 0.852
5.792LeuLeu: 5.792 ± 1.717
1.931LeuMet: 1.931 ± 1.149
5.792LeuAsn: 5.792 ± 0.865
0.0LeuPro: 0.0 ± 0.0
1.931LeuGln: 1.931 ± 1.149
1.931LeuArg: 1.931 ± 1.149
1.931LeuSer: 1.931 ± 1.149
1.931LeuThr: 1.931 ± 1.149
1.931LeuVal: 1.931 ± 1.149
1.931LeuTrp: 1.931 ± 1.433
3.861LeuTyr: 3.861 ± 0.284
0.0LeuXaa: 0.0 ± 0.0
Met
1.931MetAla: 1.931 ± 1.149
1.931MetCys: 1.931 ± 1.433
3.861MetAsp: 3.861 ± 2.298
1.931MetGlu: 1.931 ± 1.149
1.931MetPhe: 1.931 ± 1.149
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
1.931MetIle: 1.931 ± 1.149
1.931MetLys: 1.931 ± 1.433
1.931MetLeu: 1.931 ± 1.149
1.931MetMet: 1.931 ± 1.868
1.931MetAsn: 1.931 ± 1.433
0.0MetPro: 0.0 ± 0.0
1.931MetGln: 1.931 ± 1.433
0.0MetArg: 0.0 ± 0.0
0.0MetSer: 0.0 ± 0.0
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
3.861MetTyr: 3.861 ± 2.866
0.0MetXaa: 0.0 ± 0.0
Asn
3.861AsnAla: 3.861 ± 0.284
0.0AsnCys: 0.0 ± 0.0
3.861AsnAsp: 3.861 ± 2.866
0.0AsnGlu: 0.0 ± 0.0
1.931AsnPhe: 1.931 ± 1.433
5.792AsnGly: 5.792 ± 0.865
3.861AsnHis: 3.861 ± 2.866
5.792AsnIle: 5.792 ± 0.865
9.653AsnLys: 9.653 ± 0.581
3.861AsnLeu: 3.861 ± 0.284
3.861AsnMet: 3.861 ± 0.838
1.931AsnAsn: 1.931 ± 1.149
3.861AsnPro: 3.861 ± 2.298
7.722AsnGln: 7.722 ± 0.568
3.861AsnArg: 3.861 ± 2.298
3.861AsnSer: 3.861 ± 2.866
3.861AsnThr: 3.861 ± 0.284
3.861AsnVal: 3.861 ± 2.866
1.931AsnTrp: 1.931 ± 1.149
1.931AsnTyr: 1.931 ± 1.149
0.0AsnXaa: 0.0 ± 0.0
Pro
0.0ProAla: 0.0 ± 0.0
0.0ProCys: 0.0 ± 0.0
1.931ProAsp: 1.931 ± 1.149
1.931ProGlu: 1.931 ± 1.149
1.931ProPhe: 1.931 ± 1.149
0.0ProGly: 0.0 ± 0.0
1.931ProHis: 1.931 ± 1.149
1.931ProIle: 1.931 ± 1.149
5.792ProLys: 5.792 ± 1.717
0.0ProLeu: 0.0 ± 0.0
0.0ProMet: 0.0 ± 0.0
3.861ProAsn: 3.861 ± 0.284
1.931ProPro: 1.931 ± 1.149
1.931ProGln: 1.931 ± 1.149
1.931ProArg: 1.931 ± 1.149
3.861ProSer: 3.861 ± 2.866
1.931ProThr: 1.931 ± 1.433
0.0ProVal: 0.0 ± 0.0
1.931ProTrp: 1.931 ± 1.149
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
3.861GlnAla: 3.861 ± 2.298
0.0GlnCys: 0.0 ± 0.0
1.931GlnAsp: 1.931 ± 1.149
0.0GlnGlu: 0.0 ± 0.0
1.931GlnPhe: 1.931 ± 1.433
3.861GlnGly: 3.861 ± 0.284
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
3.861GlnLys: 3.861 ± 2.866
1.931GlnLeu: 1.931 ± 1.149
1.931GlnMet: 1.931 ± 1.149
0.0GlnAsn: 0.0 ± 0.0
0.0GlnPro: 0.0 ± 0.0
0.0GlnGln: 0.0 ± 0.0
5.792GlnArg: 5.792 ± 1.717
0.0GlnSer: 0.0 ± 0.0
0.0GlnThr: 0.0 ± 0.0
1.931GlnVal: 1.931 ± 1.433
0.0GlnTrp: 0.0 ± 0.0
1.931GlnTyr: 1.931 ± 1.433
0.0GlnXaa: 0.0 ± 0.0
Arg
3.861ArgAla: 3.861 ± 0.284
3.861ArgCys: 3.861 ± 2.298
3.861ArgAsp: 3.861 ± 2.298
0.0ArgGlu: 0.0 ± 0.0
3.861ArgPhe: 3.861 ± 0.284
0.0ArgGly: 0.0 ± 0.0
1.931ArgHis: 1.931 ± 1.149
5.792ArgIle: 5.792 ± 1.717
1.931ArgLys: 1.931 ± 1.433
1.931ArgLeu: 1.931 ± 1.433
0.0ArgMet: 0.0 ± 0.0
5.792ArgAsn: 5.792 ± 0.865
1.931ArgPro: 1.931 ± 1.149
0.0ArgGln: 0.0 ± 0.0
9.653ArgArg: 9.653 ± 7.165
7.722ArgSer: 7.722 ± 2.014
3.861ArgThr: 3.861 ± 0.284
5.792ArgVal: 5.792 ± 4.299
3.861ArgTrp: 3.861 ± 2.298
3.861ArgTyr: 3.861 ± 2.866
0.0ArgXaa: 0.0 ± 0.0
Ser
0.0SerAla: 0.0 ± 0.0
0.0SerCys: 0.0 ± 0.0
0.0SerAsp: 0.0 ± 0.0
0.0SerGlu: 0.0 ± 0.0
0.0SerPhe: 0.0 ± 0.0
7.722SerGly: 7.722 ± 2.014
0.0SerHis: 0.0 ± 0.0
3.861SerIle: 3.861 ± 2.298
7.722SerLys: 7.722 ± 2.014
1.931SerLeu: 1.931 ± 1.433
0.0SerMet: 0.0 ± 0.0
5.792SerAsn: 5.792 ± 1.717
3.861SerPro: 3.861 ± 2.866
0.0SerGln: 0.0 ± 0.0
7.722SerArg: 7.722 ± 3.15
3.861SerSer: 3.861 ± 0.284
9.653SerThr: 9.653 ± 4.583
3.861SerVal: 3.861 ± 2.866
1.931SerTrp: 1.931 ± 1.149
1.931SerTyr: 1.931 ± 1.149
0.0SerXaa: 0.0 ± 0.0
Thr
0.0ThrAla: 0.0 ± 0.0
0.0ThrCys: 0.0 ± 0.0
3.861ThrAsp: 3.861 ± 0.284
1.931ThrGlu: 1.931 ± 1.149
5.792ThrPhe: 5.792 ± 1.717
5.792ThrGly: 5.792 ± 0.865
1.931ThrHis: 1.931 ± 1.433
5.792ThrIle: 5.792 ± 0.865
3.861ThrLys: 3.861 ± 2.298
5.792ThrLeu: 5.792 ± 1.717
0.0ThrMet: 0.0 ± 0.0
3.861ThrAsn: 3.861 ± 2.298
0.0ThrPro: 0.0 ± 0.0
1.931ThrGln: 1.931 ± 1.433
5.792ThrArg: 5.792 ± 0.865
3.861ThrSer: 3.861 ± 2.866
3.861ThrThr: 3.861 ± 2.866
1.931ThrVal: 1.931 ± 1.149
0.0ThrTrp: 0.0 ± 0.0
3.861ThrTyr: 3.861 ± 2.866
0.0ThrXaa: 0.0 ± 0.0
Val
1.931ValAla: 1.931 ± 1.433
1.931ValCys: 1.931 ± 1.149
0.0ValAsp: 0.0 ± 0.0
5.792ValGlu: 5.792 ± 1.717
5.792ValPhe: 5.792 ± 0.865
3.861ValGly: 3.861 ± 0.284
0.0ValHis: 0.0 ± 0.0
9.653ValIle: 9.653 ± 0.581
3.861ValLys: 3.861 ± 0.284
5.792ValLeu: 5.792 ± 1.717
1.931ValMet: 1.931 ± 1.433
1.931ValAsn: 1.931 ± 1.433
0.0ValPro: 0.0 ± 0.0
0.0ValGln: 0.0 ± 0.0
5.792ValArg: 5.792 ± 1.717
1.931ValSer: 1.931 ± 1.433
1.931ValThr: 1.931 ± 1.433
0.0ValVal: 0.0 ± 0.0
0.0ValTrp: 0.0 ± 0.0
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
1.931TrpCys: 1.931 ± 1.149
3.861TrpAsp: 3.861 ± 0.284
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
1.931TrpGly: 1.931 ± 1.433
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
5.792TrpLys: 5.792 ± 0.865
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
1.931TrpAsn: 1.931 ± 1.433
1.931TrpPro: 1.931 ± 1.149
1.931TrpGln: 1.931 ± 1.433
0.0TrpArg: 0.0 ± 0.0
1.931TrpSer: 1.931 ± 1.149
1.931TrpThr: 1.931 ± 1.149
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.931TrpTyr: 1.931 ± 1.149
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.931TyrAla: 1.931 ± 1.433
3.861TyrCys: 3.861 ± 2.298
0.0TyrAsp: 0.0 ± 0.0
1.931TyrGlu: 1.931 ± 1.149
3.861TyrPhe: 3.861 ± 2.298
1.931TyrGly: 1.931 ± 1.433
0.0TyrHis: 0.0 ± 0.0
7.722TyrIle: 7.722 ± 3.15
3.861TyrLys: 3.861 ± 0.284
1.931TyrLeu: 1.931 ± 1.149
1.931TyrMet: 1.931 ± 1.149
5.792TyrAsn: 5.792 ± 4.299
3.861TyrPro: 3.861 ± 2.298
0.0TyrGln: 0.0 ± 0.0
1.931TyrArg: 1.931 ± 1.433
1.931TyrSer: 1.931 ± 1.433
0.0TyrThr: 0.0 ± 0.0
1.931TyrVal: 1.931 ± 1.433
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (519 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski