Amino acid dipepetide frequency for Paraburkholderia phytofirmans OLGA172

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	16.747AlaAla: 16.747 ± 0.209	1.291AlaCys: 1.291 ± 0.026	6.476AlaAsp: 6.476 ± 0.062	6.206AlaGlu: 6.206 ± 0.069	4.234AlaPhe: 4.234 ± 0.045	9.806AlaGly: 9.806 ± 0.07	2.775AlaHis: 2.775 ± 0.036	5.693AlaIle: 5.693 ± 0.055	3.885AlaLys: 3.885 ± 0.052	13.509AlaLeu: 13.509 ± 0.109	3.163AlaMet: 3.163 ± 0.046	3.435AlaAsn: 3.435 ± 0.043	5.58AlaPro: 5.58 ± 0.065	5.277AlaGln: 5.277 ± 0.054	8.266AlaArg: 8.266 ± 0.077	7.449AlaSer: 7.449 ± 0.065	6.378AlaThr: 6.378 ± 0.092	8.729AlaVal: 8.729 ± 0.08	1.586AlaTrp: 1.586 ± 0.026	2.699AlaTyr: 2.699 ± 0.036	0.0AlaXaa: 0.0 ± 0.0
Cys	1.208CysAla: 1.208 ± 0.025	0.133CysCys: 0.133 ± 0.008	0.554CysAsp: 0.554 ± 0.018	0.525CysGlu: 0.525 ± 0.015	0.353CysPhe: 0.353 ± 0.012	0.993CysGly: 0.993 ± 0.023	0.237CysHis: 0.237 ± 0.012	0.409CysIle: 0.409 ± 0.014	0.243CysLys: 0.243 ± 0.011	0.844CysLeu: 0.844 ± 0.022	0.203CysMet: 0.203 ± 0.01	0.26CysAsn: 0.26 ± 0.012	0.447CysPro: 0.447 ± 0.018	0.229CysGln: 0.229 ± 0.011	0.641CysArg: 0.641 ± 0.015	0.554CysSer: 0.554 ± 0.016	0.478CysThr: 0.478 ± 0.015	0.799CysVal: 0.799 ± 0.021	0.132CysTrp: 0.132 ± 0.007	0.234CysTyr: 0.234 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	7.248AspAla: 7.248 ± 0.08	0.467AspCys: 0.467 ± 0.014	3.047AspAsp: 3.047 ± 0.043	3.41AspGlu: 3.41 ± 0.041	1.995AspPhe: 1.995 ± 0.033	4.502AspGly: 4.502 ± 0.054	1.177AspHis: 1.177 ± 0.023	2.614AspIle: 2.614 ± 0.04	1.659AspLys: 1.659 ± 0.031	5.267AspLeu: 5.267 ± 0.06	1.174AspMet: 1.174 ± 0.023	1.397AspAsn: 1.397 ± 0.029	2.811AspPro: 2.811 ± 0.044	1.657AspGln: 1.657 ± 0.026	3.322AspArg: 3.322 ± 0.046	2.714AspSer: 2.714 ± 0.034	2.892AspThr: 2.892 ± 0.034	4.313AspVal: 4.313 ± 0.046	0.928AspTrp: 0.928 ± 0.022	1.506AspTyr: 1.506 ± 0.026	0.0AspXaa: 0.0 ± 0.0
Glu	6.55GluAla: 6.55 ± 0.068	0.422GluCys: 0.422 ± 0.017	2.259GluAsp: 2.259 ± 0.038	2.532GluGlu: 2.532 ± 0.051	1.878GluPhe: 1.878 ± 0.035	3.439GluGly: 3.439 ± 0.043	1.469GluHis: 1.469 ± 0.026	2.88GluIle: 2.88 ± 0.044	1.934GluLys: 1.934 ± 0.031	5.646GluLeu: 5.646 ± 0.057	1.281GluMet: 1.281 ± 0.026	1.486GluAsn: 1.486 ± 0.026	2.48GluPro: 2.48 ± 0.038	2.486GluGln: 2.486 ± 0.042	4.774GluArg: 4.774 ± 0.053	2.777GluSer: 2.777 ± 0.039	2.974GluThr: 2.974 ± 0.039	3.655GluVal: 3.655 ± 0.049	0.763GluTrp: 0.763 ± 0.017	1.234GluTyr: 1.234 ± 0.025	0.0GluXaa: 0.0 ± 0.0
Phe	4.586PheAla: 4.586 ± 0.049	0.438PheCys: 0.438 ± 0.016	2.734PheAsp: 2.734 ± 0.038	2.095PheGlu: 2.095 ± 0.03	1.469PhePhe: 1.469 ± 0.033	3.669PheGly: 3.669 ± 0.044	0.754PheHis: 0.754 ± 0.02	1.647PheIle: 1.647 ± 0.029	1.113PheLys: 1.113 ± 0.023	3.05PheLeu: 3.05 ± 0.039	0.838PheMet: 0.838 ± 0.019	1.236PheAsn: 1.236 ± 0.024	1.566PhePro: 1.566 ± 0.027	0.995PheGln: 0.995 ± 0.02	2.092PheArg: 2.092 ± 0.033	2.396PheSer: 2.396 ± 0.033	1.969PheThr: 1.969 ± 0.033	3.048PheVal: 3.048 ± 0.044	0.506PheTrp: 0.506 ± 0.015	0.996PheTyr: 0.996 ± 0.022	0.0PheXaa: 0.0 ± 0.0
Gly	8.928GlyAla: 8.928 ± 0.075	0.826GlyCys: 0.826 ± 0.022	3.879GlyAsp: 3.879 ± 0.046	4.259GlyGlu: 4.259 ± 0.049	3.443GlyPhe: 3.443 ± 0.043	6.592GlyGly: 6.592 ± 0.094	1.916GlyHis: 1.916 ± 0.031	4.163GlyIle: 4.163 ± 0.042	3.316GlyLys: 3.316 ± 0.045	7.797GlyLeu: 7.797 ± 0.07	2.13GlyMet: 2.13 ± 0.035	2.47GlyAsn: 2.47 ± 0.041	2.82GlyPro: 2.82 ± 0.037	2.734GlyGln: 2.734 ± 0.038	4.973GlyArg: 4.973 ± 0.043	4.745GlySer: 4.745 ± 0.059	4.589GlyThr: 4.589 ± 0.077	6.509GlyVal: 6.509 ± 0.06	1.327GlyTrp: 1.327 ± 0.025	2.426GlyTyr: 2.426 ± 0.04	0.0GlyXaa: 0.0 ± 0.0
His	2.97HisAla: 2.97 ± 0.039	0.281HisCys: 0.281 ± 0.011	1.359HisAsp: 1.359 ± 0.025	1.243HisGlu: 1.243 ± 0.024	0.995HisPhe: 0.995 ± 0.021	2.13HisGly: 2.13 ± 0.032	0.651HisHis: 0.651 ± 0.017	0.977HisIle: 0.977 ± 0.024	0.579HisLys: 0.579 ± 0.018	2.194HisLeu: 2.194 ± 0.032	0.561HisMet: 0.561 ± 0.017	0.545HisAsn: 0.545 ± 0.016	1.422HisPro: 1.422 ± 0.023	0.692HisGln: 0.692 ± 0.017	1.547HisArg: 1.547 ± 0.028	1.184HisSer: 1.184 ± 0.024	1.196HisThr: 1.196 ± 0.031	1.736HisVal: 1.736 ± 0.025	0.391HisTrp: 0.391 ± 0.014	0.69HisTyr: 0.69 ± 0.018	0.0HisXaa: 0.0 ± 0.0
Ile	6.849IleAla: 6.849 ± 0.058	0.486IleCys: 0.486 ± 0.015	3.437IleAsp: 3.437 ± 0.042	3.377IleGlu: 3.377 ± 0.048	1.54IlePhe: 1.54 ± 0.03	4.601IleGly: 4.601 ± 0.053	0.947IleHis: 0.947 ± 0.022	1.72IleIle: 1.72 ± 0.031	1.466IleLys: 1.466 ± 0.027	3.498IleLeu: 3.498 ± 0.037	0.783IleMet: 0.783 ± 0.019	1.497IleAsn: 1.497 ± 0.029	2.203IlePro: 2.203 ± 0.028	1.346IleGln: 1.346 ± 0.028	2.898IleArg: 2.898 ± 0.036	2.725IleSer: 2.725 ± 0.039	2.585IleThr: 2.585 ± 0.07	4.318IleVal: 4.318 ± 0.047	0.499IleTrp: 0.499 ± 0.016	1.102IleTyr: 1.102 ± 0.021	0.0IleXaa: 0.0 ± 0.0
Lys	3.707LysAla: 3.707 ± 0.056	0.199LysCys: 0.199 ± 0.011	1.594LysAsp: 1.594 ± 0.032	1.565LysGlu: 1.565 ± 0.03	0.995LysPhe: 0.995 ± 0.023	2.285LysGly: 2.285 ± 0.037	0.73LysHis: 0.73 ± 0.02	1.655LysIle: 1.655 ± 0.03	1.36LysLys: 1.36 ± 0.034	3.549LysLeu: 3.549 ± 0.049	0.83LysMet: 0.83 ± 0.017	0.973LysAsn: 0.973 ± 0.022	2.027LysPro: 2.027 ± 0.029	1.369LysGln: 1.369 ± 0.028	2.548LysArg: 2.548 ± 0.036	1.83LysSer: 1.83 ± 0.03	2.008LysThr: 2.008 ± 0.034	2.432LysVal: 2.432 ± 0.037	0.416LysTrp: 0.416 ± 0.015	0.789LysTyr: 0.789 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	13.26LeuAla: 13.26 ± 0.1	1.019LeuCys: 1.019 ± 0.026	5.866LeuAsp: 5.866 ± 0.058	5.201LeuGlu: 5.201 ± 0.055	3.641LeuPhe: 3.641 ± 0.046	7.83LeuGly: 7.83 ± 0.074	2.292LeuHis: 2.292 ± 0.035	4.779LeuIle: 4.779 ± 0.047	3.568LeuLys: 3.568 ± 0.043	9.941LeuLeu: 9.941 ± 0.089	2.216LeuMet: 2.216 ± 0.036	2.994LeuAsn: 2.994 ± 0.045	5.56LeuPro: 5.56 ± 0.057	3.456LeuGln: 3.456 ± 0.044	7.043LeuArg: 7.043 ± 0.067	6.539LeuSer: 6.539 ± 0.065	5.725LeuThr: 5.725 ± 0.059	7.275LeuVal: 7.275 ± 0.065	1.168LeuTrp: 1.168 ± 0.026	2.234LeuTyr: 2.234 ± 0.036	0.0LeuXaa: 0.0 ± 0.0
Met	2.496MetAla: 2.496 ± 0.04	0.183MetCys: 0.183 ± 0.009	0.96MetAsp: 0.96 ± 0.023	0.961MetGlu: 0.961 ± 0.021	0.779MetPhe: 0.779 ± 0.018	1.537MetGly: 1.537 ± 0.026	0.572MetHis: 0.572 ± 0.015	1.112MetIle: 1.112 ± 0.022	1.07MetLys: 1.07 ± 0.023	2.625MetLeu: 2.625 ± 0.041	0.567MetMet: 0.567 ± 0.017	0.938MetAsn: 0.938 ± 0.021	1.441MetPro: 1.441 ± 0.026	0.999MetGln: 0.999 ± 0.021	1.79MetArg: 1.79 ± 0.028	1.703MetSer: 1.703 ± 0.025	1.613MetThr: 1.613 ± 0.028	1.579MetVal: 1.579 ± 0.028	0.217MetTrp: 0.217 ± 0.011	0.411MetTyr: 0.411 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	3.672AsnAla: 3.672 ± 0.047	0.291AsnCys: 0.291 ± 0.011	1.53AsnAsp: 1.53 ± 0.029	1.424AsnGlu: 1.424 ± 0.027	1.067AsnPhe: 1.067 ± 0.026	2.766AsnGly: 2.766 ± 0.048	0.596AsnHis: 0.596 ± 0.015	1.308AsnIle: 1.308 ± 0.026	0.772AsnLys: 0.772 ± 0.021	2.863AsnLeu: 2.863 ± 0.042	0.604AsnMet: 0.604 ± 0.015	0.913AsnAsn: 0.913 ± 0.026	1.873AsnPro: 1.873 ± 0.03	0.986AsnGln: 0.986 ± 0.02	1.915AsnArg: 1.915 ± 0.032	1.567AsnSer: 1.567 ± 0.035	1.635AsnThr: 1.635 ± 0.041	2.354AsnVal: 2.354 ± 0.032	0.465AsnTrp: 0.465 ± 0.014	0.758AsnTyr: 0.758 ± 0.018	0.0AsnXaa: 0.0 ± 0.0
Pro	6.243ProAla: 6.243 ± 0.067	0.344ProCys: 0.344 ± 0.012	3.151ProAsp: 3.151 ± 0.039	3.036ProGlu: 3.036 ± 0.04	1.907ProPhe: 1.907 ± 0.029	4.008ProGly: 4.008 ± 0.051	1.263ProHis: 1.263 ± 0.026	2.083ProIle: 2.083 ± 0.028	1.553ProLys: 1.553 ± 0.029	5.07ProLeu: 5.07 ± 0.053	1.113ProMet: 1.113 ± 0.023	1.466ProAsn: 1.466 ± 0.026	2.388ProPro: 2.388 ± 0.039	1.927ProGln: 1.927 ± 0.034	2.76ProArg: 2.76 ± 0.044	2.91ProSer: 2.91 ± 0.04	2.576ProThr: 2.576 ± 0.036	4.223ProVal: 4.223 ± 0.049	0.632ProTrp: 0.632 ± 0.016	1.236ProTyr: 1.236 ± 0.027	0.0ProXaa: 0.0 ± 0.0
Gln	4.514GlnAla: 4.514 ± 0.058	0.286GlnCys: 0.286 ± 0.01	1.433GlnAsp: 1.433 ± 0.027	1.45GlnGlu: 1.45 ± 0.027	1.365GlnPhe: 1.365 ± 0.023	2.445GlnGly: 2.445 ± 0.035	0.967GlnHis: 0.967 ± 0.021	2.125GlnIle: 2.125 ± 0.035	1.194GlnLys: 1.194 ± 0.025	3.942GlnLeu: 3.942 ± 0.051	1.032GlnMet: 1.032 ± 0.022	1.009GlnAsn: 1.009 ± 0.022	2.069GlnPro: 2.069 ± 0.034	2.037GlnGln: 2.037 ± 0.044	2.998GlnArg: 2.998 ± 0.04	2.113GlnSer: 2.113 ± 0.03	2.127GlnThr: 2.127 ± 0.032	2.539GlnVal: 2.539 ± 0.034	0.572GlnTrp: 0.572 ± 0.017	0.974GlnTyr: 0.974 ± 0.019	0.0GlnXaa: 0.0 ± 0.0
Arg	7.696ArgAla: 7.696 ± 0.059	0.613ArgCys: 0.613 ± 0.018	3.681ArgAsp: 3.681 ± 0.042	4.251ArgGlu: 4.251 ± 0.052	2.891ArgPhe: 2.891 ± 0.042	4.419ArgGly: 4.419 ± 0.047	1.872ArgHis: 1.872 ± 0.028	3.589ArgIle: 3.589 ± 0.046	2.211ArgLys: 2.211 ± 0.034	7.12ArgLeu: 7.12 ± 0.075	1.733ArgMet: 1.733 ± 0.027	2.014ArgAsn: 2.014 ± 0.033	2.957ArgPro: 2.957 ± 0.037	2.647ArgGln: 2.647 ± 0.04	5.189ArgArg: 5.189 ± 0.062	3.69ArgSer: 3.69 ± 0.045	3.453ArgThr: 3.453 ± 0.044	5.138ArgVal: 5.138 ± 0.059	1.067ArgTrp: 1.067 ± 0.023	2.014ArgTyr: 2.014 ± 0.03	0.0ArgXaa: 0.0 ± 0.0
Ser	7.113SerAla: 7.113 ± 0.061	0.501SerCys: 0.501 ± 0.018	3.013SerAsp: 3.013 ± 0.039	2.804SerGlu: 2.804 ± 0.036	2.26SerPhe: 2.26 ± 0.032	5.504SerGly: 5.504 ± 0.075	1.29SerHis: 1.29 ± 0.025	2.926SerIle: 2.926 ± 0.037	1.801SerLys: 1.801 ± 0.03	5.882SerLeu: 5.882 ± 0.06	1.459SerMet: 1.459 ± 0.027	1.841SerAsn: 1.841 ± 0.029	2.917SerPro: 2.917 ± 0.038	2.011SerGln: 2.011 ± 0.036	3.794SerArg: 3.794 ± 0.046	3.744SerSer: 3.744 ± 0.046	3.332SerThr: 3.332 ± 0.054	4.555SerVal: 4.555 ± 0.047	0.757SerTrp: 0.757 ± 0.018	1.408SerTyr: 1.408 ± 0.028	0.0SerXaa: 0.0 ± 0.0
Thr	6.164ThrAla: 6.164 ± 0.072	0.441ThrCys: 0.441 ± 0.015	2.771ThrAsp: 2.771 ± 0.05	2.486ThrGlu: 2.486 ± 0.036	2.013ThrPhe: 2.013 ± 0.032	4.818ThrGly: 4.818 ± 0.066	1.298ThrHis: 1.298 ± 0.023	2.757ThrIle: 2.757 ± 0.065	1.412ThrLys: 1.412 ± 0.03	6.479ThrLeu: 6.479 ± 0.061	1.186ThrMet: 1.186 ± 0.022	1.435ThrAsn: 1.435 ± 0.031	3.467ThrPro: 3.467 ± 0.049	2.094ThrGln: 2.094 ± 0.041	3.546ThrArg: 3.546 ± 0.043	3.212ThrSer: 3.212 ± 0.065	3.032ThrThr: 3.032 ± 0.077	4.464ThrVal: 4.464 ± 0.055	0.717ThrTrp: 0.717 ± 0.021	1.374ThrTyr: 1.374 ± 0.026	0.0ThrXaa: 0.0 ± 0.0
Val	9.254ValAla: 9.254 ± 0.078	0.821ValCys: 0.821 ± 0.02	4.336ValAsp: 4.336 ± 0.042	4.276ValGlu: 4.276 ± 0.044	2.778ValPhe: 2.778 ± 0.039	5.518ValGly: 5.518 ± 0.052	1.584ValHis: 1.584 ± 0.03	3.795ValIle: 3.795 ± 0.043	2.584ValLys: 2.584 ± 0.044	7.77ValLeu: 7.77 ± 0.065	1.851ValMet: 1.851 ± 0.039	2.295ValAsn: 2.295 ± 0.035	3.908ValPro: 3.908 ± 0.04	2.608ValGln: 2.608 ± 0.034	5.039ValArg: 5.039 ± 0.046	4.849ValSer: 4.849 ± 0.049	4.572ValThr: 4.572 ± 0.063	6.172ValVal: 6.172 ± 0.062	0.955ValTrp: 0.955 ± 0.024	1.755ValTyr: 1.755 ± 0.027	0.0ValXaa: 0.0 ± 0.0
Trp	1.154TrpAla: 1.154 ± 0.028	0.154TrpCys: 0.154 ± 0.01	0.618TrpAsp: 0.618 ± 0.016	0.522TrpGlu: 0.522 ± 0.012	0.57TrpPhe: 0.57 ± 0.017	0.845TrpGly: 0.845 ± 0.02	0.422TrpHis: 0.422 ± 0.014	0.73TrpIle: 0.73 ± 0.018	0.47TrpLys: 0.47 ± 0.015	1.909TrpLeu: 1.909 ± 0.037	0.358TrpMet: 0.358 ± 0.013	0.477TrpAsn: 0.477 ± 0.018	0.661TrpPro: 0.661 ± 0.02	0.69TrpGln: 0.69 ± 0.02	1.144TrpArg: 1.144 ± 0.024	0.807TrpSer: 0.807 ± 0.02	0.708TrpThr: 0.708 ± 0.017	0.956TrpVal: 0.956 ± 0.02	0.211TrpTrp: 0.211 ± 0.011	0.321TrpTyr: 0.321 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.824TyrAla: 2.824 ± 0.037	0.279TyrCys: 0.279 ± 0.011	1.402TyrAsp: 1.402 ± 0.026	1.295TyrGlu: 1.295 ± 0.025	1.024TyrPhe: 1.024 ± 0.019	2.135TyrGly: 2.135 ± 0.032	0.53TyrHis: 0.53 ± 0.018	0.917TyrIle: 0.917 ± 0.023	0.674TyrLys: 0.674 ± 0.018	2.652TyrLeu: 2.652 ± 0.041	0.473TyrMet: 0.473 ± 0.016	0.678TyrAsn: 0.678 ± 0.018	1.29TyrPro: 1.29 ± 0.025	0.95TyrGln: 0.95 ± 0.022	1.967TyrArg: 1.967 ± 0.033	1.406TyrSer: 1.406 ± 0.027	1.324TyrThr: 1.324 ± 0.027	1.924TyrVal: 1.924 ± 0.029	0.417TyrTrp: 0.417 ± 0.015	0.67TyrTyr: 0.67 ± 0.017	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 7096 proteins (2227262 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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