Amino acid dipepetide frequency for Xylanibacterium ulmi

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	25.063AlaAla: 25.063 ± 0.256	0.925AlaCys: 0.925 ± 0.03	9.361AlaAsp: 9.361 ± 0.091	7.46AlaGlu: 7.46 ± 0.1	3.787AlaPhe: 3.787 ± 0.063	13.895AlaGly: 13.895 ± 0.118	3.239AlaHis: 3.239 ± 0.059	4.676AlaIle: 4.676 ± 0.073	2.241AlaLys: 2.241 ± 0.053	16.071AlaLeu: 16.071 ± 0.153	2.725AlaMet: 2.725 ± 0.048	2.081AlaAsn: 2.081 ± 0.049	8.581AlaPro: 8.581 ± 0.122	4.933AlaGln: 4.933 ± 0.079	11.935AlaArg: 11.935 ± 0.132	7.248AlaSer: 7.248 ± 0.082	8.52AlaThr: 8.52 ± 0.086	13.856AlaVal: 13.856 ± 0.136	2.417AlaTrp: 2.417 ± 0.057	2.496AlaTyr: 2.496 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	0.887CysAla: 0.887 ± 0.026	0.058CysCys: 0.058 ± 0.007	0.383CysAsp: 0.383 ± 0.018	0.317CysGlu: 0.317 ± 0.018	0.128CysPhe: 0.128 ± 0.01	0.708CysGly: 0.708 ± 0.028	0.134CysHis: 0.134 ± 0.012	0.078CysIle: 0.078 ± 0.009	0.063CysLys: 0.063 ± 0.007	0.522CysLeu: 0.522 ± 0.021	0.077CysMet: 0.077 ± 0.008	0.084CysAsn: 0.084 ± 0.008	0.386CysPro: 0.386 ± 0.021	0.138CysGln: 0.138 ± 0.01	0.391CysArg: 0.391 ± 0.019	0.334CysSer: 0.334 ± 0.018	0.285CysThr: 0.285 ± 0.017	0.605CysVal: 0.605 ± 0.024	0.089CysTrp: 0.089 ± 0.009	0.101CysTyr: 0.101 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	9.732AspAla: 9.732 ± 0.107	0.276AspCys: 0.276 ± 0.016	4.779AspAsp: 4.779 ± 0.076	3.66AspGlu: 3.66 ± 0.062	1.353AspPhe: 1.353 ± 0.034	6.934AspGly: 6.934 ± 0.095	1.316AspHis: 1.316 ± 0.035	1.611AspIle: 1.611 ± 0.04	0.904AspLys: 0.904 ± 0.029	6.83AspLeu: 6.83 ± 0.08	0.632AspMet: 0.632 ± 0.024	0.849AspAsn: 0.849 ± 0.028	4.583AspPro: 4.583 ± 0.068	1.569AspGln: 1.569 ± 0.035	4.152AspArg: 4.152 ± 0.06	2.075AspSer: 2.075 ± 0.046	2.752AspThr: 2.752 ± 0.046	6.771AspVal: 6.771 ± 0.079	0.848AspTrp: 0.848 ± 0.028	1.058AspTyr: 1.058 ± 0.03	0.0AspXaa: 0.0 ± 0.0
Glu	7.26GluAla: 7.26 ± 0.101	0.246GluCys: 0.246 ± 0.014	2.367GluAsp: 2.367 ± 0.051	2.276GluGlu: 2.276 ± 0.052	1.242GluPhe: 1.242 ± 0.035	3.703GluGly: 3.703 ± 0.067	1.545GluHis: 1.545 ± 0.043	1.996GluIle: 1.996 ± 0.048	0.79GluLys: 0.79 ± 0.034	5.33GluLeu: 5.33 ± 0.082	0.745GluMet: 0.745 ± 0.027	0.827GluAsn: 0.827 ± 0.029	3.401GluPro: 3.401 ± 0.059	1.946GluGln: 1.946 ± 0.044	5.535GluArg: 5.535 ± 0.081	2.289GluSer: 2.289 ± 0.041	2.612GluThr: 2.612 ± 0.056	4.739GluVal: 4.739 ± 0.076	0.702GluTrp: 0.702 ± 0.025	0.971GluTyr: 0.971 ± 0.029	0.0GluXaa: 0.0 ± 0.0
Phe	3.95PheAla: 3.95 ± 0.062	0.21PheCys: 0.21 ± 0.014	2.045PheAsp: 2.045 ± 0.047	1.494PheGlu: 1.494 ± 0.038	0.816PhePhe: 0.816 ± 0.033	2.984PheGly: 2.984 ± 0.059	0.528PheHis: 0.528 ± 0.021	0.706PheIle: 0.706 ± 0.026	0.374PheLys: 0.374 ± 0.02	2.342PheLeu: 2.342 ± 0.055	0.34PheMet: 0.34 ± 0.018	0.483PheAsn: 0.483 ± 0.022	1.195PhePro: 1.195 ± 0.037	0.632PheGln: 0.632 ± 0.023	1.547PheArg: 1.547 ± 0.033	1.304PheSer: 1.304 ± 0.032	1.677PheThr: 1.677 ± 0.039	2.565PheVal: 2.565 ± 0.056	0.464PheTrp: 0.464 ± 0.022	0.522PheTyr: 0.522 ± 0.023	0.0PheXaa: 0.0 ± 0.0
Gly	13.649GlyAla: 13.649 ± 0.144	0.584GlyCys: 0.584 ± 0.024	5.358GlyAsp: 5.358 ± 0.081	4.768GlyGlu: 4.768 ± 0.073	2.817GlyPhe: 2.817 ± 0.056	8.279GlyGly: 8.279 ± 0.113	2.006GlyHis: 2.006 ± 0.044	2.856GlyIle: 2.856 ± 0.053	1.881GlyLys: 1.881 ± 0.044	9.518GlyLeu: 9.518 ± 0.092	1.844GlyMet: 1.844 ± 0.041	1.413GlyAsn: 1.413 ± 0.04	4.881GlyPro: 4.881 ± 0.075	2.774GlyGln: 2.774 ± 0.048	7.122GlyArg: 7.122 ± 0.077	4.959GlySer: 4.959 ± 0.069	4.981GlyThr: 4.981 ± 0.076	9.55GlyVal: 9.55 ± 0.1	1.72GlyTrp: 1.72 ± 0.04	1.997GlyTyr: 1.997 ± 0.047	0.0GlyXaa: 0.0 ± 0.0
His	2.978HisAla: 2.978 ± 0.06	0.123HisCys: 0.123 ± 0.01	1.472HisAsp: 1.472 ± 0.037	1.149HisGlu: 1.149 ± 0.032	0.471HisPhe: 0.471 ± 0.022	2.118HisGly: 2.118 ± 0.043	0.603HisHis: 0.603 ± 0.027	0.544HisIle: 0.544 ± 0.022	0.286HisLys: 0.286 ± 0.015	2.35HisLeu: 2.35 ± 0.044	0.267HisMet: 0.267 ± 0.015	0.355HisAsn: 0.355 ± 0.016	1.562HisPro: 1.562 ± 0.039	0.558HisGln: 0.558 ± 0.023	1.687HisArg: 1.687 ± 0.043	0.808HisSer: 0.808 ± 0.027	1.192HisThr: 1.192 ± 0.036	1.928HisVal: 1.928 ± 0.039	0.281HisTrp: 0.281 ± 0.017	0.392HisTyr: 0.392 ± 0.018	0.0HisXaa: 0.0 ± 0.0
Ile	5.306IleAla: 5.306 ± 0.074	0.207IleCys: 0.207 ± 0.014	2.471IleAsp: 2.471 ± 0.055	1.961IleGlu: 1.961 ± 0.043	0.73IlePhe: 0.73 ± 0.031	3.361IleGly: 3.361 ± 0.063	0.503IleHis: 0.503 ± 0.024	0.964IleIle: 0.964 ± 0.033	0.602IleLys: 0.602 ± 0.027	2.593IleLeu: 2.593 ± 0.052	0.443IleMet: 0.443 ± 0.021	0.555IleAsn: 0.555 ± 0.023	1.687IlePro: 1.687 ± 0.041	0.632IleGln: 0.632 ± 0.024	1.777IleArg: 1.777 ± 0.046	1.454IleSer: 1.454 ± 0.041	2.264IleThr: 2.264 ± 0.043	3.253IleVal: 3.253 ± 0.058	0.337IleTrp: 0.337 ± 0.017	0.505IleTyr: 0.505 ± 0.02	0.0IleXaa: 0.0 ± 0.0
Lys	2.227LysAla: 2.227 ± 0.053	0.061LysCys: 0.061 ± 0.007	0.903LysAsp: 0.903 ± 0.033	0.783LysGlu: 0.783 ± 0.028	0.327LysPhe: 0.327 ± 0.018	1.27LysGly: 1.27 ± 0.04	0.363LysHis: 0.363 ± 0.017	0.625LysIle: 0.625 ± 0.029	0.455LysLys: 0.455 ± 0.027	1.245LysLeu: 1.245 ± 0.039	0.247LysMet: 0.247 ± 0.016	0.377LysAsn: 0.377 ± 0.018	0.961LysPro: 0.961 ± 0.032	0.453LysGln: 0.453 ± 0.02	1.17LysArg: 1.17 ± 0.037	0.858LysSer: 0.858 ± 0.033	1.003LysThr: 1.003 ± 0.032	1.529LysVal: 1.529 ± 0.041	0.164LysTrp: 0.164 ± 0.011	0.362LysTyr: 0.362 ± 0.021	0.0LysXaa: 0.0 ± 0.0
Leu	17.122LeuAla: 17.122 ± 0.152	0.546LeuCys: 0.546 ± 0.025	7.312LeuAsp: 7.312 ± 0.091	4.493LeuGlu: 4.493 ± 0.072	2.368LeuPhe: 2.368 ± 0.06	9.723LeuGly: 9.723 ± 0.11	1.892LeuHis: 1.892 ± 0.039	2.934LeuIle: 2.934 ± 0.059	1.33LeuLys: 1.33 ± 0.038	10.115LeuLeu: 10.115 ± 0.116	1.406LeuMet: 1.406 ± 0.038	1.415LeuAsn: 1.415 ± 0.038	5.729LeuPro: 5.729 ± 0.069	2.033LeuGln: 2.033 ± 0.041	8.502LeuArg: 8.502 ± 0.106	4.825LeuSer: 4.825 ± 0.065	6.837LeuThr: 6.837 ± 0.078	10.136LeuVal: 10.136 ± 0.115	1.292LeuTrp: 1.292 ± 0.037	1.528LeuTyr: 1.528 ± 0.038	0.0LeuXaa: 0.0 ± 0.0
Met	2.093MetAla: 2.093 ± 0.044	0.11MetCys: 0.11 ± 0.009	0.744MetAsp: 0.744 ± 0.024	0.534MetGlu: 0.534 ± 0.025	0.435MetPhe: 0.435 ± 0.021	1.203MetGly: 1.203 ± 0.037	0.271MetHis: 0.271 ± 0.017	0.593MetIle: 0.593 ± 0.024	0.242MetLys: 0.242 ± 0.015	1.643MetLeu: 1.643 ± 0.042	0.232MetMet: 0.232 ± 0.017	0.328MetAsn: 0.328 ± 0.02	1.036MetPro: 1.036 ± 0.024	0.376MetGln: 0.376 ± 0.017	1.45MetArg: 1.45 ± 0.033	1.344MetSer: 1.344 ± 0.032	1.658MetThr: 1.658 ± 0.035	1.393MetVal: 1.393 ± 0.034	0.176MetTrp: 0.176 ± 0.013	0.227MetTyr: 0.227 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	2.141AsnAla: 2.141 ± 0.046	0.094AsnCys: 0.094 ± 0.008	0.923AsnAsp: 0.923 ± 0.035	0.715AsnGlu: 0.715 ± 0.027	0.454AsnPhe: 0.454 ± 0.021	1.446AsnGly: 1.446 ± 0.039	0.344AsnHis: 0.344 ± 0.017	0.547AsnIle: 0.547 ± 0.028	0.276AsnLys: 0.276 ± 0.017	1.692AsnLeu: 1.692 ± 0.039	0.233AsnMet: 0.233 ± 0.015	0.374AsnAsn: 0.374 ± 0.02	1.366AsnPro: 1.366 ± 0.039	0.443AsnGln: 0.443 ± 0.02	0.968AsnArg: 0.968 ± 0.036	0.65AsnSer: 0.65 ± 0.026	0.939AsnThr: 0.939 ± 0.032	1.53AsnVal: 1.53 ± 0.039	0.224AsnTrp: 0.224 ± 0.014	0.335AsnTyr: 0.335 ± 0.019	0.0AsnXaa: 0.0 ± 0.0
Pro	8.985ProAla: 8.985 ± 0.128	0.25ProCys: 0.25 ± 0.013	4.427ProAsp: 4.427 ± 0.069	3.517ProGlu: 3.517 ± 0.051	1.536ProPhe: 1.536 ± 0.037	6.137ProGly: 6.137 ± 0.076	1.343ProHis: 1.343 ± 0.036	1.625ProIle: 1.625 ± 0.036	0.72ProLys: 0.72 ± 0.028	5.19ProLeu: 5.19 ± 0.076	0.874ProMet: 0.874 ± 0.03	0.867ProAsn: 0.867 ± 0.031	3.119ProPro: 3.119 ± 0.068	1.842ProGln: 1.842 ± 0.037	4.119ProArg: 4.119 ± 0.066	3.372ProSer: 3.372 ± 0.051	4.176ProThr: 4.176 ± 0.078	5.526ProVal: 5.526 ± 0.071	0.931ProTrp: 0.931 ± 0.027	1.008ProTyr: 1.008 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	4.22GlnAla: 4.22 ± 0.055	0.14GlnCys: 0.14 ± 0.01	1.393GlnAsp: 1.393 ± 0.033	1.288GlnGlu: 1.288 ± 0.032	0.788GlnPhe: 0.788 ± 0.028	2.29GlnGly: 2.29 ± 0.043	0.61GlnHis: 0.61 ± 0.022	1.213GlnIle: 1.213 ± 0.034	0.372GlnLys: 0.372 ± 0.018	2.459GlnLeu: 2.459 ± 0.043	0.498GlnMet: 0.498 ± 0.021	0.475GlnAsn: 0.475 ± 0.021	1.546GlnPro: 1.546 ± 0.037	0.966GlnGln: 0.966 ± 0.036	2.387GlnArg: 2.387 ± 0.048	1.201GlnSer: 1.201 ± 0.034	1.585GlnThr: 1.585 ± 0.039	3.102GlnVal: 3.102 ± 0.054	0.473GlnTrp: 0.473 ± 0.018	0.555GlnTyr: 0.555 ± 0.027	0.0GlnXaa: 0.0 ± 0.0
Arg	11.327ArgAla: 11.327 ± 0.129	0.393ArgCys: 0.393 ± 0.021	4.362ArgAsp: 4.362 ± 0.071	4.407ArgGlu: 4.407 ± 0.069	2.14ArgPhe: 2.14 ± 0.047	6.013ArgGly: 6.013 ± 0.092	1.839ArgHis: 1.839 ± 0.046	2.549ArgIle: 2.549 ± 0.048	1.185ArgLys: 1.185 ± 0.029	8.473ArgLeu: 8.473 ± 0.105	1.633ArgMet: 1.633 ± 0.039	1.126ArgAsn: 1.126 ± 0.036	4.685ArgPro: 4.685 ± 0.077	2.157ArgGln: 2.157 ± 0.045	7.971ArgArg: 7.971 ± 0.121	3.876ArgSer: 3.876 ± 0.065	4.729ArgThr: 4.729 ± 0.072	7.132ArgVal: 7.132 ± 0.076	1.458ArgTrp: 1.458 ± 0.037	1.579ArgTyr: 1.579 ± 0.034	0.0ArgXaa: 0.0 ± 0.0
Ser	7.024SerAla: 7.024 ± 0.092	0.272SerCys: 0.272 ± 0.017	2.823SerAsp: 2.823 ± 0.052	1.972SerGlu: 1.972 ± 0.044	1.411SerPhe: 1.411 ± 0.036	5.523SerGly: 5.523 ± 0.076	0.917SerHis: 0.917 ± 0.027	1.668SerIle: 1.668 ± 0.043	0.786SerLys: 0.786 ± 0.027	4.847SerLeu: 4.847 ± 0.056	0.942SerMet: 0.942 ± 0.026	0.83SerAsn: 0.83 ± 0.027	3.175SerPro: 3.175 ± 0.05	1.368SerGln: 1.368 ± 0.031	3.472SerArg: 3.472 ± 0.059	2.552SerSer: 2.552 ± 0.054	3.34SerThr: 3.34 ± 0.066	4.364SerVal: 4.364 ± 0.063	0.805SerTrp: 0.805 ± 0.03	0.883SerTyr: 0.883 ± 0.029	0.0SerXaa: 0.0 ± 0.0
Thr	8.527ThrAla: 8.527 ± 0.097	0.381ThrCys: 0.381 ± 0.022	3.199ThrAsp: 3.199 ± 0.053	2.448ThrGlu: 2.448 ± 0.049	1.843ThrPhe: 1.843 ± 0.052	6.011ThrGly: 6.011 ± 0.079	1.304ThrHis: 1.304 ± 0.031	2.251ThrIle: 2.251 ± 0.043	0.956ThrLys: 0.956 ± 0.034	6.385ThrLeu: 6.385 ± 0.078	0.946ThrMet: 0.946 ± 0.029	0.962ThrAsn: 0.962 ± 0.03	4.771ThrPro: 4.771 ± 0.082	1.645ThrGln: 1.645 ± 0.044	4.186ThrArg: 4.186 ± 0.064	3.375ThrSer: 3.375 ± 0.061	4.496ThrThr: 4.496 ± 0.086	5.968ThrVal: 5.968 ± 0.085	1.001ThrTrp: 1.001 ± 0.033	1.187ThrTyr: 1.187 ± 0.035	0.0ThrXaa: 0.0 ± 0.0
Val	14.568ValAla: 14.568 ± 0.126	0.638ValCys: 0.638 ± 0.026	6.203ValAsp: 6.203 ± 0.081	5.691ValGlu: 5.691 ± 0.083	2.46ValPhe: 2.46 ± 0.05	8.547ValGly: 8.547 ± 0.094	1.704ValHis: 1.704 ± 0.037	3.232ValIle: 3.232 ± 0.054	1.433ValLys: 1.433 ± 0.04	10.129ValLeu: 10.129 ± 0.119	1.536ValMet: 1.536 ± 0.037	1.602ValAsn: 1.602 ± 0.041	5.192ValPro: 5.192 ± 0.074	1.972ValGln: 1.972 ± 0.043	7.774ValArg: 7.774 ± 0.096	4.655ValSer: 4.655 ± 0.067	6.692ValThr: 6.692 ± 0.085	11.79ValVal: 11.79 ± 0.12	1.261ValTrp: 1.261 ± 0.037	1.588ValTyr: 1.588 ± 0.043	0.0ValXaa: 0.0 ± 0.0
Trp	2.003TrpAla: 2.003 ± 0.049	0.134TrpCys: 0.134 ± 0.01	0.92TrpAsp: 0.92 ± 0.03	0.601TrpGlu: 0.601 ± 0.022	0.544TrpPhe: 0.544 ± 0.022	1.081TrpGly: 1.081 ± 0.031	0.342TrpHis: 0.342 ± 0.018	0.484TrpIle: 0.484 ± 0.022	0.207TrpLys: 0.207 ± 0.013	1.778TrpLeu: 1.778 ± 0.047	0.252TrpMet: 0.252 ± 0.014	0.347TrpAsn: 0.347 ± 0.016	0.769TrpPro: 0.769 ± 0.03	0.562TrpGln: 0.562 ± 0.025	1.39TrpArg: 1.39 ± 0.035	0.928TrpSer: 0.928 ± 0.023	1.038TrpThr: 1.038 ± 0.031	1.292TrpVal: 1.292 ± 0.034	0.407TrpTrp: 0.407 ± 0.019	0.279TrpTyr: 0.279 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.449TyrAla: 2.449 ± 0.053	0.122TyrCys: 0.122 ± 0.01	1.24TyrAsp: 1.24 ± 0.035	0.988TyrGlu: 0.988 ± 0.036	0.525TyrPhe: 0.525 ± 0.021	1.731TyrGly: 1.731 ± 0.043	0.322TyrHis: 0.322 ± 0.019	0.455TyrIle: 0.455 ± 0.022	0.279TyrLys: 0.279 ± 0.017	2.028TyrLeu: 2.028 ± 0.041	0.216TyrMet: 0.216 ± 0.014	0.343TyrAsn: 0.343 ± 0.019	0.938TyrPro: 0.938 ± 0.032	0.558TyrGln: 0.558 ± 0.021	1.498TyrArg: 1.498 ± 0.04	0.867TyrSer: 0.867 ± 0.03	1.068TyrThr: 1.068 ± 0.039	1.638TyrVal: 1.638 ± 0.037	0.308TyrTrp: 0.308 ± 0.015	0.37TyrTyr: 0.37 ± 0.018	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3500 proteins (1185822 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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