Amino acid dipepetide frequency for Tortoise microvirus 106

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.521AlaAla: 1.521 ± 1.561
1.521AlaCys: 1.521 ± 0.674
3.042AlaAsp: 3.042 ± 1.311
3.042AlaGlu: 3.042 ± 1.446
2.281AlaPhe: 2.281 ± 1.003
3.802AlaGly: 3.802 ± 2.245
1.521AlaHis: 1.521 ± 1.419
3.042AlaIle: 3.042 ± 0.911
0.0AlaLys: 0.0 ± 0.0
6.084AlaLeu: 6.084 ± 1.737
0.76AlaMet: 0.76 ± 0.709
3.042AlaAsn: 3.042 ± 0.995
2.281AlaPro: 2.281 ± 1.427
1.521AlaGln: 1.521 ± 1.419
3.802AlaArg: 3.802 ± 1.733
3.042AlaSer: 3.042 ± 1.014
3.802AlaThr: 3.802 ± 1.601
3.042AlaVal: 3.042 ± 1.314
1.521AlaTrp: 1.521 ± 0.674
1.521AlaTyr: 1.521 ± 0.723
0.0AlaXaa: 0.0 ± 0.0
Cys
0.76CysAla: 0.76 ± 0.709
0.76CysCys: 0.76 ± 0.478
3.042CysAsp: 3.042 ± 1.008
0.76CysGlu: 0.76 ± 0.478
0.0CysPhe: 0.0 ± 0.0
0.76CysGly: 0.76 ± 0.709
0.76CysHis: 0.76 ± 0.834
0.76CysIle: 0.76 ± 0.709
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.76CysGln: 0.76 ± 0.478
1.521CysArg: 1.521 ± 1.419
0.76CysSer: 0.76 ± 0.709
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.76CysTyr: 0.76 ± 0.709
0.0CysXaa: 0.0 ± 0.0
Asp
5.323AspAla: 5.323 ± 1.813
0.0AspCys: 0.0 ± 0.0
0.0AspAsp: 0.0 ± 0.0
3.802AspGlu: 3.802 ± 1.999
3.042AspPhe: 3.042 ± 1.612
0.76AspGly: 0.76 ± 0.979
0.0AspHis: 0.0 ± 0.0
4.563AspIle: 4.563 ± 1.361
2.281AspLys: 2.281 ± 0.945
4.563AspLeu: 4.563 ± 1.44
1.521AspMet: 1.521 ± 0.956
2.281AspAsn: 2.281 ± 1.488
2.281AspPro: 2.281 ± 1.03
0.76AspGln: 0.76 ± 0.478
1.521AspArg: 1.521 ± 0.916
3.802AspSer: 3.802 ± 1.787
2.281AspThr: 2.281 ± 1.433
3.042AspVal: 3.042 ± 1.832
1.521AspTrp: 1.521 ± 1.419
6.844AspTyr: 6.844 ± 1.595
0.0AspXaa: 0.0 ± 0.0
Glu
1.521GluAla: 1.521 ± 0.723
0.76GluCys: 0.76 ± 0.834
3.802GluAsp: 3.802 ± 1.803
1.521GluGlu: 1.521 ± 1.098
2.281GluPhe: 2.281 ± 0.945
3.802GluGly: 3.802 ± 1.034
2.281GluHis: 2.281 ± 0.621
4.563GluIle: 4.563 ± 1.514
3.802GluLys: 3.802 ± 1.831
3.802GluLeu: 3.802 ± 2.236
0.76GluMet: 0.76 ± 0.698
9.125GluAsn: 9.125 ± 3.39
3.802GluPro: 3.802 ± 0.763
0.76GluGln: 0.76 ± 0.478
6.084GluArg: 6.084 ± 2.343
6.084GluSer: 6.084 ± 2.142
4.563GluThr: 4.563 ± 0.786
3.042GluVal: 3.042 ± 1.911
0.76GluTrp: 0.76 ± 0.979
3.042GluTyr: 3.042 ± 1.911
0.0GluXaa: 0.0 ± 0.0
Phe
1.521PheAla: 1.521 ± 0.956
0.0PheCys: 0.0 ± 0.0
3.042PheAsp: 3.042 ± 1.388
3.802PheGlu: 3.802 ± 1.026
3.042PhePhe: 3.042 ± 1.117
5.323PheGly: 5.323 ± 2.662
0.0PheHis: 0.0 ± 0.0
2.281PheIle: 2.281 ± 0.945
2.281PheLys: 2.281 ± 0.929
5.323PheLeu: 5.323 ± 1.443
0.0PheMet: 0.0 ± 0.0
2.281PheAsn: 2.281 ± 1.003
0.0PhePro: 0.0 ± 0.0
2.281PheGln: 2.281 ± 1.433
2.281PheArg: 2.281 ± 1.433
4.563PheSer: 4.563 ± 1.755
2.281PheThr: 2.281 ± 1.084
4.563PheVal: 4.563 ± 2.553
0.76PheTrp: 0.76 ± 0.478
0.76PheTyr: 0.76 ± 0.709
0.0PheXaa: 0.0 ± 0.0
Gly
3.802GlyAla: 3.802 ± 1.072
0.0GlyCys: 0.0 ± 0.0
0.76GlyAsp: 0.76 ± 0.478
3.802GlyGlu: 3.802 ± 1.746
1.521GlyPhe: 1.521 ± 1.419
3.042GlyGly: 3.042 ± 1.314
1.521GlyHis: 1.521 ± 0.956
0.76GlyIle: 0.76 ± 0.834
2.281GlyLys: 2.281 ± 0.878
7.605GlyLeu: 7.605 ± 3.394
3.802GlyMet: 3.802 ± 1.463
3.802GlyAsn: 3.802 ± 1.794
0.0GlyPro: 0.0 ± 0.0
0.76GlyGln: 0.76 ± 0.781
1.521GlyArg: 1.521 ± 0.674
8.365GlySer: 8.365 ± 1.127
1.521GlyThr: 1.521 ± 0.956
3.802GlyVal: 3.802 ± 1.613
0.0GlyTrp: 0.0 ± 0.0
3.042GlyTyr: 3.042 ± 1.911
0.0GlyXaa: 0.0 ± 0.0
His
0.76HisAla: 0.76 ± 0.709
0.0HisCys: 0.0 ± 0.0
0.76HisAsp: 0.76 ± 0.834
0.76HisGlu: 0.76 ± 0.834
0.76HisPhe: 0.76 ± 0.478
2.281HisGly: 2.281 ± 0.929
0.0HisHis: 0.0 ± 0.0
0.76HisIle: 0.76 ± 0.709
0.76HisLys: 0.76 ± 0.709
1.521HisLeu: 1.521 ± 0.723
0.76HisMet: 0.76 ± 0.478
2.281HisAsn: 2.281 ± 0.929
1.521HisPro: 1.521 ± 0.674
1.521HisGln: 1.521 ± 0.956
0.76HisArg: 0.76 ± 0.478
0.76HisSer: 0.76 ± 0.979
0.0HisThr: 0.0 ± 0.0
1.521HisVal: 1.521 ± 0.956
0.0HisTrp: 0.0 ± 0.0
3.042HisTyr: 3.042 ± 2.838
0.0HisXaa: 0.0 ± 0.0
Ile
1.521IleAla: 1.521 ± 0.956
1.521IleCys: 1.521 ± 0.674
1.521IleAsp: 1.521 ± 0.674
2.281IleGlu: 2.281 ± 1.419
3.042IlePhe: 3.042 ± 1.403
2.281IleGly: 2.281 ± 1.134
0.0IleHis: 0.0 ± 0.0
1.521IleIle: 1.521 ± 0.916
3.802IleLys: 3.802 ± 2.287
6.844IleLeu: 6.844 ± 1.716
3.042IleMet: 3.042 ± 1.733
2.281IleAsn: 2.281 ± 0.621
4.563IlePro: 4.563 ± 3.253
2.281IleGln: 2.281 ± 1.299
3.802IleArg: 3.802 ± 1.267
3.042IleSer: 3.042 ± 0.758
2.281IleThr: 2.281 ± 1.084
3.042IleVal: 3.042 ± 0.995
1.521IleTrp: 1.521 ± 0.674
2.281IleTyr: 2.281 ± 0.621
0.0IleXaa: 0.0 ± 0.0
Lys
1.521LysAla: 1.521 ± 0.916
0.0LysCys: 0.0 ± 0.0
8.365LysAsp: 8.365 ± 1.647
5.323LysGlu: 5.323 ± 1.443
2.281LysPhe: 2.281 ± 1.433
3.802LysGly: 3.802 ± 1.429
0.76LysHis: 0.76 ± 0.709
3.042LysIle: 3.042 ± 1.06
8.365LysLys: 8.365 ± 2.926
3.802LysLeu: 3.802 ± 2.236
2.281LysMet: 2.281 ± 0.946
3.802LysAsn: 3.802 ± 3.829
3.802LysPro: 3.802 ± 0.954
3.042LysGln: 3.042 ± 2.012
3.042LysArg: 3.042 ± 1.462
3.802LysSer: 3.802 ± 2.06
3.042LysThr: 3.042 ± 1.457
0.0LysVal: 0.0 ± 0.0
0.0LysTrp: 0.0 ± 0.0
5.323LysTyr: 5.323 ± 3.029
0.0LysXaa: 0.0 ± 0.0
Leu
2.281LeuAla: 2.281 ± 1.427
1.521LeuCys: 1.521 ± 1.098
5.323LeuAsp: 5.323 ± 2.488
6.084LeuGlu: 6.084 ± 1.567
6.844LeuPhe: 6.844 ± 4.453
4.563LeuGly: 4.563 ± 2.177
1.521LeuHis: 1.521 ± 0.956
7.605LeuIle: 7.605 ± 1.793
6.084LeuLys: 6.084 ± 4.188
6.084LeuLeu: 6.084 ± 3.569
4.563LeuMet: 4.563 ± 1.717
5.323LeuAsn: 5.323 ± 2.386
7.605LeuPro: 7.605 ± 2.283
5.323LeuGln: 5.323 ± 0.956
4.563LeuArg: 4.563 ± 1.244
8.365LeuSer: 8.365 ± 2.434
6.084LeuThr: 6.084 ± 2.985
2.281LeuVal: 2.281 ± 1.084
0.76LeuTrp: 0.76 ± 0.781
3.042LeuTyr: 3.042 ± 0.995
0.0LeuXaa: 0.0 ± 0.0
Met
4.563MetAla: 4.563 ± 1.605
0.0MetCys: 0.0 ± 0.0
0.76MetAsp: 0.76 ± 0.979
3.042MetGlu: 3.042 ± 0.911
0.76MetPhe: 0.76 ± 0.709
1.521MetGly: 1.521 ± 0.723
1.521MetHis: 1.521 ± 0.956
0.76MetIle: 0.76 ± 0.709
3.042MetLys: 3.042 ± 1.915
3.802MetLeu: 3.802 ± 0.565
0.0MetMet: 0.0 ± 0.0
2.281MetAsn: 2.281 ± 1.427
0.76MetPro: 0.76 ± 0.478
1.521MetGln: 1.521 ± 1.419
0.76MetArg: 0.76 ± 0.709
0.0MetSer: 0.0 ± 0.0
0.76MetThr: 0.76 ± 0.478
2.281MetVal: 2.281 ± 1.57
0.0MetTrp: 0.0 ± 0.0
0.76MetTyr: 0.76 ± 0.478
0.0MetXaa: 0.0 ± 0.0
Asn
3.802AsnAla: 3.802 ± 1.366
0.0AsnCys: 0.0 ± 0.0
2.281AsnAsp: 2.281 ± 1.003
5.323AsnGlu: 5.323 ± 1.496
0.0AsnPhe: 0.0 ± 0.0
0.76AsnGly: 0.76 ± 0.709
1.521AsnHis: 1.521 ± 0.806
5.323AsnIle: 5.323 ± 1.401
7.605AsnLys: 7.605 ± 1.218
5.323AsnLeu: 5.323 ± 2.694
1.521AsnMet: 1.521 ± 0.956
6.084AsnAsn: 6.084 ± 1.288
4.563AsnPro: 4.563 ± 1.835
3.802AsnGln: 3.802 ± 2.236
3.042AsnArg: 3.042 ± 1.846
4.563AsnSer: 4.563 ± 1.345
4.563AsnThr: 4.563 ± 1.987
3.042AsnVal: 3.042 ± 1.311
0.0AsnTrp: 0.0 ± 0.0
3.802AsnTyr: 3.802 ± 2.225
0.0AsnXaa: 0.0 ± 0.0
Pro
3.042ProAla: 3.042 ± 1.348
1.521ProCys: 1.521 ± 1.419
3.802ProAsp: 3.802 ± 1.281
3.802ProGlu: 3.802 ± 1.803
2.281ProPhe: 2.281 ± 1.835
2.281ProGly: 2.281 ± 0.94
0.76ProHis: 0.76 ± 0.709
4.563ProIle: 4.563 ± 1.523
0.76ProLys: 0.76 ± 0.834
5.323ProLeu: 5.323 ± 1.632
0.76ProMet: 0.76 ± 0.478
3.042ProAsn: 3.042 ± 1.446
1.521ProPro: 1.521 ± 0.806
3.042ProGln: 3.042 ± 1.388
1.521ProArg: 1.521 ± 0.674
3.802ProSer: 3.802 ± 2.461
1.521ProThr: 1.521 ± 0.723
3.802ProVal: 3.802 ± 0.763
0.76ProTrp: 0.76 ± 0.478
3.802ProTyr: 3.802 ± 1.463
0.0ProXaa: 0.0 ± 0.0
Gln
2.281GlnAla: 2.281 ± 1.427
0.76GlnCys: 0.76 ± 0.478
1.521GlnAsp: 1.521 ± 0.723
2.281GlnGlu: 2.281 ± 0.945
1.521GlnPhe: 1.521 ± 0.674
0.76GlnGly: 0.76 ± 0.478
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
5.323GlnLys: 5.323 ± 1.669
6.844GlnLeu: 6.844 ± 2.531
2.281GlnMet: 2.281 ± 1.488
2.281GlnAsn: 2.281 ± 1.427
1.521GlnPro: 1.521 ± 0.956
4.563GlnGln: 4.563 ± 2.99
3.802GlnArg: 3.802 ± 1.242
5.323GlnSer: 5.323 ± 1.439
3.042GlnThr: 3.042 ± 1.008
0.0GlnVal: 0.0 ± 0.0
0.76GlnTrp: 0.76 ± 0.709
1.521GlnTyr: 1.521 ± 1.201
0.0GlnXaa: 0.0 ± 0.0
Arg
1.521ArgAla: 1.521 ± 0.806
0.76ArgCys: 0.76 ± 0.709
3.802ArgAsp: 3.802 ± 0.565
4.563ArgGlu: 4.563 ± 2.169
2.281ArgPhe: 2.281 ± 0.929
3.042ArgGly: 3.042 ± 1.311
0.0ArgHis: 0.0 ± 0.0
1.521ArgIle: 1.521 ± 0.916
4.563ArgLys: 4.563 ± 1.885
7.605ArgLeu: 7.605 ± 1.077
1.521ArgMet: 1.521 ± 1.46
3.042ArgAsn: 3.042 ± 1.06
2.281ArgPro: 2.281 ± 1.433
1.521ArgGln: 1.521 ± 0.956
4.563ArgArg: 4.563 ± 1.209
3.042ArgSer: 3.042 ± 2.514
2.281ArgThr: 2.281 ± 1.03
1.521ArgVal: 1.521 ± 0.674
3.042ArgTrp: 3.042 ± 1.014
5.323ArgTyr: 5.323 ± 1.666
0.0ArgXaa: 0.0 ± 0.0
Ser
8.365SerAla: 8.365 ± 2.44
0.0SerCys: 0.0 ± 0.0
2.281SerAsp: 2.281 ± 1.34
7.605SerGlu: 7.605 ± 2.005
5.323SerPhe: 5.323 ± 1.086
3.802SerGly: 3.802 ± 1.228
0.0SerHis: 0.0 ± 0.0
2.281SerIle: 2.281 ± 2.937
3.042SerLys: 3.042 ± 1.462
7.605SerLeu: 7.605 ± 4.458
2.281SerMet: 2.281 ± 1.623
4.563SerAsn: 4.563 ± 2.123
6.084SerPro: 6.084 ± 2.24
3.042SerGln: 3.042 ± 1.644
3.802SerArg: 3.802 ± 1.026
4.563SerSer: 4.563 ± 1.209
1.521SerThr: 1.521 ± 0.956
3.802SerVal: 3.802 ± 2.884
0.0SerTrp: 0.0 ± 0.0
4.563SerTyr: 4.563 ± 1.442
0.0SerXaa: 0.0 ± 0.0
Thr
1.521ThrAla: 1.521 ± 0.956
0.76ThrCys: 0.76 ± 0.478
2.281ThrAsp: 2.281 ± 1.299
3.042ThrGlu: 3.042 ± 1.314
2.281ThrPhe: 2.281 ± 1.433
4.563ThrGly: 4.563 ± 2.219
2.281ThrHis: 2.281 ± 2.128
5.323ThrIle: 5.323 ± 1.748
3.802ThrLys: 3.802 ± 1.944
6.084ThrLeu: 6.084 ± 1.881
1.521ThrMet: 1.521 ± 1.098
2.281ThrAsn: 2.281 ± 1.089
3.042ThrPro: 3.042 ± 1.644
2.281ThrGln: 2.281 ± 1.427
0.76ThrArg: 0.76 ± 0.478
1.521ThrSer: 1.521 ± 0.956
1.521ThrThr: 1.521 ± 0.916
2.281ThrVal: 2.281 ± 1.003
0.0ThrTrp: 0.0 ± 0.0
0.76ThrTyr: 0.76 ± 0.709
0.0ThrXaa: 0.0 ± 0.0
Val
1.521ValAla: 1.521 ± 0.674
0.0ValCys: 0.0 ± 0.0
0.76ValAsp: 0.76 ± 0.478
1.521ValGlu: 1.521 ± 0.806
1.521ValPhe: 1.521 ± 0.956
2.281ValGly: 2.281 ± 0.945
4.563ValHis: 4.563 ± 1.523
0.76ValIle: 0.76 ± 0.478
3.042ValLys: 3.042 ± 1.62
2.281ValLeu: 2.281 ± 1.084
0.76ValMet: 0.76 ± 0.979
2.281ValAsn: 2.281 ± 0.946
3.802ValPro: 3.802 ± 1.16
0.76ValGln: 0.76 ± 0.478
5.323ValArg: 5.323 ± 2.038
7.605ValSer: 7.605 ± 3.39
2.281ValThr: 2.281 ± 0.929
3.802ValVal: 3.802 ± 1.221
0.76ValTrp: 0.76 ± 0.478
2.281ValTyr: 2.281 ± 1.427
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.76TrpCys: 0.76 ± 0.709
0.76TrpAsp: 0.76 ± 0.781
0.76TrpGlu: 0.76 ± 0.478
1.521TrpPhe: 1.521 ± 0.916
0.0TrpGly: 0.0 ± 0.0
0.76TrpHis: 0.76 ± 0.478
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
1.521TrpLeu: 1.521 ± 1.08
0.0TrpMet: 0.0 ± 0.0
2.281TrpAsn: 2.281 ± 0.929
0.76TrpPro: 0.76 ± 0.478
0.0TrpGln: 0.0 ± 0.0
0.76TrpArg: 0.76 ± 0.781
0.0TrpSer: 0.0 ± 0.0
1.521TrpThr: 1.521 ± 0.674
0.76TrpVal: 0.76 ± 0.781
0.0TrpTrp: 0.0 ± 0.0
0.76TrpTyr: 0.76 ± 0.709
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.042TyrAla: 3.042 ± 1.911
0.76TyrCys: 0.76 ± 0.709
2.281TyrAsp: 2.281 ± 0.929
3.802TyrGlu: 3.802 ± 2.335
3.802TyrPhe: 3.802 ± 1.746
2.281TyrGly: 2.281 ± 0.621
0.76TyrHis: 0.76 ± 0.709
3.042TyrIle: 3.042 ± 2.161
4.563TyrLys: 4.563 ± 0.592
3.802TyrLeu: 3.802 ± 1.551
0.0TyrMet: 0.0 ± 0.0
4.563TyrAsn: 4.563 ± 1.209
1.521TyrPro: 1.521 ± 0.956
6.844TyrGln: 6.844 ± 4.168
4.563TyrArg: 4.563 ± 1.835
1.521TyrSer: 1.521 ± 0.866
3.042TyrThr: 3.042 ± 0.911
2.281TyrVal: 2.281 ± 1.299
0.76TyrTrp: 0.76 ± 0.781
1.521TyrTyr: 1.521 ± 1.098
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1316 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski