Amino acid dipepetide frequency for Candidatus Electrothrix aarhusiensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.898AlaAla: 7.898 ± 0.119	1.127AlaCys: 1.127 ± 0.039	4.634AlaAsp: 4.634 ± 0.074	6.078AlaGlu: 6.078 ± 0.094	3.111AlaPhe: 3.111 ± 0.058	6.426AlaGly: 6.426 ± 0.084	1.448AlaHis: 1.448 ± 0.037	4.431AlaIle: 4.431 ± 0.069	3.986AlaLys: 3.986 ± 0.064	8.522AlaLeu: 8.522 ± 0.094	2.22AlaMet: 2.22 ± 0.051	2.409AlaAsn: 2.409 ± 0.055	2.752AlaPro: 2.752 ± 0.052	2.921AlaGln: 2.921 ± 0.052	3.901AlaArg: 3.901 ± 0.066	4.346AlaSer: 4.346 ± 0.062	3.732AlaThr: 3.732 ± 0.064	6.43AlaVal: 6.43 ± 0.084	0.879AlaTrp: 0.879 ± 0.027	2.013AlaTyr: 2.013 ± 0.049	0.0AlaXaa: 0.0 ± 0.0
Cys	0.941CysAla: 0.941 ± 0.032	0.331CysCys: 0.331 ± 0.021	0.663CysAsp: 0.663 ± 0.027	0.726CysGlu: 0.726 ± 0.033	0.648CysPhe: 0.648 ± 0.024	1.18CysGly: 1.18 ± 0.038	0.386CysHis: 0.386 ± 0.025	0.747CysIle: 0.747 ± 0.026	0.549CysLys: 0.549 ± 0.026	1.431CysLeu: 1.431 ± 0.037	0.326CysMet: 0.326 ± 0.018	0.499CysAsn: 0.499 ± 0.021	0.796CysPro: 0.796 ± 0.032	0.548CysGln: 0.548 ± 0.023	0.946CysArg: 0.946 ± 0.029	1.09CysSer: 1.09 ± 0.032	0.751CysThr: 0.751 ± 0.029	0.686CysVal: 0.686 ± 0.025	0.209CysTrp: 0.209 ± 0.016	0.44CysTyr: 0.44 ± 0.019	0.001CysXaa: 0.001 ± 0.001
Asp	3.924AspAla: 3.924 ± 0.067	0.766AspCys: 0.766 ± 0.03	2.919AspAsp: 2.919 ± 0.077	3.805AspGlu: 3.805 ± 0.071	2.753AspPhe: 2.753 ± 0.055	3.72AspGly: 3.72 ± 0.076	1.091AspHis: 1.091 ± 0.034	3.998AspIle: 3.998 ± 0.069	3.143AspLys: 3.143 ± 0.055	5.538AspLeu: 5.538 ± 0.077	1.365AspMet: 1.365 ± 0.038	2.187AspAsn: 2.187 ± 0.05	2.585AspPro: 2.585 ± 0.055	2.266AspGln: 2.266 ± 0.042	2.853AspArg: 2.853 ± 0.05	3.167AspSer: 3.167 ± 0.059	2.716AspThr: 2.716 ± 0.054	3.16AspVal: 3.16 ± 0.058	0.817AspTrp: 0.817 ± 0.026	1.778AspTyr: 1.778 ± 0.047	0.0AspXaa: 0.0 ± 0.0
Glu	5.285GluAla: 5.285 ± 0.077	0.599GluCys: 0.599 ± 0.028	3.352GluAsp: 3.352 ± 0.073	5.665GluGlu: 5.665 ± 0.094	2.312GluPhe: 2.312 ± 0.053	3.952GluGly: 3.952 ± 0.067	1.544GluHis: 1.544 ± 0.041	4.7GluIle: 4.7 ± 0.071	5.446GluLys: 5.446 ± 0.081	7.02GluLeu: 7.02 ± 0.097	1.784GluMet: 1.784 ± 0.041	2.846GluAsn: 2.846 ± 0.05	2.171GluPro: 2.171 ± 0.046	4.343GluGln: 4.343 ± 0.074	3.784GluArg: 3.784 ± 0.059	3.274GluSer: 3.274 ± 0.068	3.194GluThr: 3.194 ± 0.061	4.075GluVal: 4.075 ± 0.065	0.673GluTrp: 0.673 ± 0.029	2.04GluTyr: 2.04 ± 0.049	0.0GluXaa: 0.0 ± 0.0
Phe	3.239PheAla: 3.239 ± 0.062	0.774PheCys: 0.774 ± 0.028	2.458PheAsp: 2.458 ± 0.055	2.089PheGlu: 2.089 ± 0.045	2.773PhePhe: 2.773 ± 0.062	2.924PheGly: 2.924 ± 0.056	1.001PheHis: 1.001 ± 0.027	2.835PheIle: 2.835 ± 0.058	1.81PheLys: 1.81 ± 0.046	4.931PheLeu: 4.931 ± 0.074	0.994PheMet: 0.994 ± 0.03	1.578PheAsn: 1.578 ± 0.037	1.861PhePro: 1.861 ± 0.044	1.633PheGln: 1.633 ± 0.039	2.214PheArg: 2.214 ± 0.046	3.585PheSer: 3.585 ± 0.061	2.472PheThr: 2.472 ± 0.049	2.442PheVal: 2.442 ± 0.048	0.557PheTrp: 0.557 ± 0.022	1.408PheTyr: 1.408 ± 0.039	0.0PheXaa: 0.0 ± 0.0
Gly	4.826GlyAla: 4.826 ± 0.077	1.16GlyCys: 1.16 ± 0.033	3.556GlyAsp: 3.556 ± 0.076	4.412GlyGlu: 4.412 ± 0.075	3.127GlyPhe: 3.127 ± 0.054	4.954GlyGly: 4.954 ± 0.088	1.503GlyHis: 1.503 ± 0.037	5.078GlyIle: 5.078 ± 0.08	4.719GlyLys: 4.719 ± 0.065	6.844GlyLeu: 6.844 ± 0.098	2.169GlyMet: 2.169 ± 0.048	2.706GlyAsn: 2.706 ± 0.054	2.045GlyPro: 2.045 ± 0.049	2.701GlyGln: 2.701 ± 0.058	3.949GlyArg: 3.949 ± 0.073	4.311GlySer: 4.311 ± 0.074	3.945GlyThr: 3.945 ± 0.082	4.459GlyVal: 4.459 ± 0.065	0.917GlyTrp: 0.917 ± 0.03	2.353GlyTyr: 2.353 ± 0.05	0.0GlyXaa: 0.0 ± 0.0
His	1.527HisAla: 1.527 ± 0.036	0.377HisCys: 0.377 ± 0.019	1.107HisAsp: 1.107 ± 0.035	1.261HisGlu: 1.261 ± 0.034	1.044HisPhe: 1.044 ± 0.031	1.545HisGly: 1.545 ± 0.04	0.621HisHis: 0.621 ± 0.024	1.407HisIle: 1.407 ± 0.035	1.055HisLys: 1.055 ± 0.028	2.323HisLeu: 2.323 ± 0.05	0.42HisMet: 0.42 ± 0.019	0.852HisAsn: 0.852 ± 0.026	1.227HisPro: 1.227 ± 0.038	0.934HisGln: 0.934 ± 0.03	1.228HisArg: 1.228 ± 0.039	1.324HisSer: 1.324 ± 0.034	1.059HisThr: 1.059 ± 0.029	1.17HisVal: 1.17 ± 0.036	0.263HisTrp: 0.263 ± 0.014	0.713HisTyr: 0.713 ± 0.029	0.0HisXaa: 0.0 ± 0.0
Ile	5.219IleAla: 5.219 ± 0.078	0.947IleCys: 0.947 ± 0.029	3.67IleAsp: 3.67 ± 0.062	4.057IleGlu: 4.057 ± 0.062	2.839IlePhe: 2.839 ± 0.061	4.417IleGly: 4.417 ± 0.076	1.424IleHis: 1.424 ± 0.04	4.598IleIle: 4.598 ± 0.074	3.491IleLys: 3.491 ± 0.064	6.469IleLeu: 6.469 ± 0.077	1.527IleMet: 1.527 ± 0.034	2.697IleAsn: 2.697 ± 0.055	2.932IlePro: 2.932 ± 0.053	2.259IleGln: 2.259 ± 0.044	3.824IleArg: 3.824 ± 0.06	4.622IleSer: 4.622 ± 0.076	3.752IleThr: 3.752 ± 0.071	3.697IleVal: 3.697 ± 0.058	0.632IleTrp: 0.632 ± 0.028	1.776IleTyr: 1.776 ± 0.047	0.0IleXaa: 0.0 ± 0.0
Lys	4.4LysAla: 4.4 ± 0.076	0.537LysCys: 0.537 ± 0.025	3.026LysAsp: 3.026 ± 0.062	4.909LysGlu: 4.909 ± 0.085	1.675LysPhe: 1.675 ± 0.047	3.849LysGly: 3.849 ± 0.07	1.08LysHis: 1.08 ± 0.032	4.277LysIle: 4.277 ± 0.072	5.812LysLys: 5.812 ± 0.107	4.787LysLeu: 4.787 ± 0.072	1.605LysMet: 1.605 ± 0.046	2.914LysAsn: 2.914 ± 0.061	2.091LysPro: 2.091 ± 0.045	2.482LysGln: 2.482 ± 0.055	3.018LysArg: 3.018 ± 0.052	2.97LysSer: 2.97 ± 0.051	3.17LysThr: 3.17 ± 0.052	3.458LysVal: 3.458 ± 0.061	0.483LysTrp: 0.483 ± 0.024	1.829LysTyr: 1.829 ± 0.044	0.0LysXaa: 0.0 ± 0.0
Leu	9.129LeuAla: 9.129 ± 0.107	1.42LeuCys: 1.42 ± 0.044	5.734LeuAsp: 5.734 ± 0.075	6.406LeuGlu: 6.406 ± 0.088	4.914LeuPhe: 4.914 ± 0.08	6.348LeuGly: 6.348 ± 0.08	2.497LeuHis: 2.497 ± 0.041	6.34LeuIle: 6.34 ± 0.082	5.474LeuLys: 5.474 ± 0.078	12.084LeuLeu: 12.084 ± 0.146	2.236LeuMet: 2.236 ± 0.046	3.677LeuAsn: 3.677 ± 0.061	5.266LeuPro: 5.266 ± 0.072	4.063LeuGln: 4.063 ± 0.067	5.737LeuArg: 5.737 ± 0.08	7.107LeuSer: 7.107 ± 0.085	5.598LeuThr: 5.598 ± 0.074	6.306LeuVal: 6.306 ± 0.078	1.012LeuTrp: 1.012 ± 0.032	2.903LeuTyr: 2.903 ± 0.053	0.0LeuXaa: 0.0 ± 0.0
Met	2.062MetAla: 2.062 ± 0.05	0.22MetCys: 0.22 ± 0.015	1.283MetAsp: 1.283 ± 0.04	1.588MetGlu: 1.588 ± 0.04	0.776MetPhe: 0.776 ± 0.029	1.613MetGly: 1.613 ± 0.046	0.507MetHis: 0.507 ± 0.023	1.609MetIle: 1.609 ± 0.038	1.747MetLys: 1.747 ± 0.045	2.592MetLeu: 2.592 ± 0.05	0.669MetMet: 0.669 ± 0.024	1.071MetAsn: 1.071 ± 0.033	1.238MetPro: 1.238 ± 0.033	1.169MetGln: 1.169 ± 0.034	1.394MetArg: 1.394 ± 0.037	1.572MetSer: 1.572 ± 0.04	1.537MetThr: 1.537 ± 0.039	1.589MetVal: 1.589 ± 0.037	0.187MetTrp: 0.187 ± 0.013	0.54MetTyr: 0.54 ± 0.023	0.0MetXaa: 0.0 ± 0.0
Asn	2.577AsnAla: 2.577 ± 0.053	0.492AsnCys: 0.492 ± 0.022	1.995AsnAsp: 1.995 ± 0.046	2.297AsnGlu: 2.297 ± 0.046	1.607AsnPhe: 1.607 ± 0.039	2.731AsnGly: 2.731 ± 0.055	0.772AsnHis: 0.772 ± 0.032	3.0AsnIle: 3.0 ± 0.054	2.246AsnLys: 2.246 ± 0.051	3.629AsnLeu: 3.629 ± 0.057	0.959AsnMet: 0.959 ± 0.027	1.833AsnAsn: 1.833 ± 0.06	2.027AsnPro: 2.027 ± 0.041	1.526AsnGln: 1.526 ± 0.043	2.312AsnArg: 2.312 ± 0.049	2.308AsnSer: 2.308 ± 0.053	1.943AsnThr: 1.943 ± 0.049	2.021AsnVal: 2.021 ± 0.042	0.47AsnTrp: 0.47 ± 0.023	1.205AsnTyr: 1.205 ± 0.033	0.0AsnXaa: 0.0 ± 0.0
Pro	3.537ProAla: 3.537 ± 0.058	0.589ProCys: 0.589 ± 0.021	3.107ProAsp: 3.107 ± 0.06	3.799ProGlu: 3.799 ± 0.065	1.938ProPhe: 1.938 ± 0.04	3.171ProGly: 3.171 ± 0.061	0.838ProHis: 0.838 ± 0.028	2.151ProIle: 2.151 ± 0.041	2.031ProLys: 2.031 ± 0.048	4.355ProLeu: 4.355 ± 0.07	0.989ProMet: 0.989 ± 0.032	1.283ProAsn: 1.283 ± 0.037	1.892ProPro: 1.892 ± 0.051	1.514ProGln: 1.514 ± 0.04	1.621ProArg: 1.621 ± 0.04	2.47ProSer: 2.47 ± 0.05	2.034ProThr: 2.034 ± 0.051	3.587ProVal: 3.587 ± 0.064	0.535ProTrp: 0.535 ± 0.021	1.325ProTyr: 1.325 ± 0.037	0.001ProXaa: 0.001 ± 0.001
Gln	3.837GlnAla: 3.837 ± 0.059	0.478GlnCys: 0.478 ± 0.025	2.152GlnAsp: 2.152 ± 0.054	3.63GlnGlu: 3.63 ± 0.075	1.355GlnPhe: 1.355 ± 0.034	3.326GlnGly: 3.326 ± 0.058	0.971GlnHis: 0.971 ± 0.034	2.193GlnIle: 2.193 ± 0.042	2.598GlnLys: 2.598 ± 0.055	4.144GlnLeu: 4.144 ± 0.064	0.904GlnMet: 0.904 ± 0.029	1.365GlnAsn: 1.365 ± 0.034	1.654GlnPro: 1.654 ± 0.042	2.618GlnGln: 2.618 ± 0.067	2.36GlnArg: 2.36 ± 0.047	1.973GlnSer: 1.973 ± 0.043	1.822GlnThr: 1.822 ± 0.041	2.828GlnVal: 2.828 ± 0.056	0.454GlnTrp: 0.454 ± 0.017	1.331GlnTyr: 1.331 ± 0.037	0.001GlnXaa: 0.001 ± 0.001
Arg	3.478ArgAla: 3.478 ± 0.06	0.766ArgCys: 0.766 ± 0.028	2.641ArgAsp: 2.641 ± 0.047	3.711ArgGlu: 3.711 ± 0.066	2.621ArgPhe: 2.621 ± 0.05	2.86ArgGly: 2.86 ± 0.059	1.259ArgHis: 1.259 ± 0.032	3.976ArgIle: 3.976 ± 0.055	3.635ArgLys: 3.635 ± 0.056	5.988ArgLeu: 5.988 ± 0.083	1.549ArgMet: 1.549 ± 0.042	2.164ArgAsn: 2.164 ± 0.046	2.176ArgPro: 2.176 ± 0.046	2.571ArgGln: 2.571 ± 0.05	3.254ArgArg: 3.254 ± 0.067	3.211ArgSer: 3.211 ± 0.056	2.591ArgThr: 2.591 ± 0.055	3.261ArgVal: 3.261 ± 0.058	0.622ArgTrp: 0.622 ± 0.025	1.898ArgTyr: 1.898 ± 0.046	0.0ArgXaa: 0.0 ± 0.0
Ser	4.502SerAla: 4.502 ± 0.077	1.083SerCys: 1.083 ± 0.037	3.059SerAsp: 3.059 ± 0.059	3.663SerGlu: 3.663 ± 0.058	3.152SerPhe: 3.152 ± 0.057	5.15SerGly: 5.15 ± 0.072	1.199SerHis: 1.199 ± 0.032	3.623SerIle: 3.623 ± 0.068	2.967SerLys: 2.967 ± 0.063	6.785SerLeu: 6.785 ± 0.097	1.637SerMet: 1.637 ± 0.043	2.079SerAsn: 2.079 ± 0.05	2.794SerPro: 2.794 ± 0.052	2.052SerGln: 2.052 ± 0.044	3.357SerArg: 3.357 ± 0.055	4.557SerSer: 4.557 ± 0.068	3.162SerThr: 3.162 ± 0.063	4.129SerVal: 4.129 ± 0.07	0.937SerTrp: 0.937 ± 0.03	1.944SerTyr: 1.944 ± 0.046	0.0SerXaa: 0.0 ± 0.0
Thr	4.831ThrAla: 4.831 ± 0.074	0.698ThrCys: 0.698 ± 0.025	3.048ThrAsp: 3.048 ± 0.058	3.405ThrGlu: 3.405 ± 0.057	2.089ThrPhe: 2.089 ± 0.042	4.656ThrGly: 4.656 ± 0.075	0.951ThrHis: 0.951 ± 0.028	3.112ThrIle: 3.112 ± 0.056	2.316ThrLys: 2.316 ± 0.049	5.412ThrLeu: 5.412 ± 0.072	1.169ThrMet: 1.169 ± 0.031	1.619ThrAsn: 1.619 ± 0.041	2.615ThrPro: 2.615 ± 0.058	1.53ThrGln: 1.53 ± 0.039	2.374ThrArg: 2.374 ± 0.044	3.041ThrSer: 3.041 ± 0.058	2.851ThrThr: 2.851 ± 0.068	4.362ThrVal: 4.362 ± 0.065	0.621ThrTrp: 0.621 ± 0.032	1.448ThrTyr: 1.448 ± 0.046	0.0ThrXaa: 0.0 ± 0.0
Val	5.206ValAla: 5.206 ± 0.075	0.876ValCys: 0.876 ± 0.031	3.826ValAsp: 3.826 ± 0.068	4.2ValGlu: 4.2 ± 0.069	2.766ValPhe: 2.766 ± 0.051	4.142ValGly: 4.142 ± 0.069	1.428ValHis: 1.428 ± 0.038	4.241ValIle: 4.241 ± 0.063	3.192ValLys: 3.192 ± 0.059	6.803ValLeu: 6.803 ± 0.09	1.562ValMet: 1.562 ± 0.037	2.421ValAsn: 2.421 ± 0.051	2.762ValPro: 2.762 ± 0.052	2.731ValGln: 2.731 ± 0.055	3.57ValArg: 3.57 ± 0.057	4.067ValSer: 4.067 ± 0.061	3.604ValThr: 3.604 ± 0.067	4.567ValVal: 4.567 ± 0.078	0.595ValTrp: 0.595 ± 0.025	1.84ValTyr: 1.84 ± 0.043	0.001ValXaa: 0.001 ± 0.001
Trp	0.743TrpAla: 0.743 ± 0.027	0.175TrpCys: 0.175 ± 0.012	0.588TrpAsp: 0.588 ± 0.027	0.674TrpGlu: 0.674 ± 0.028	0.547TrpPhe: 0.547 ± 0.024	0.706TrpGly: 0.706 ± 0.027	0.252TrpHis: 0.252 ± 0.016	0.683TrpIle: 0.683 ± 0.025	0.686TrpLys: 0.686 ± 0.025	1.355TrpLeu: 1.355 ± 0.04	0.311TrpMet: 0.311 ± 0.019	0.499TrpAsn: 0.499 ± 0.024	0.459TrpPro: 0.459 ± 0.02	0.789TrpGln: 0.789 ± 0.026	0.633TrpArg: 0.633 ± 0.024	0.697TrpSer: 0.697 ± 0.032	0.451TrpThr: 0.451 ± 0.021	0.612TrpVal: 0.612 ± 0.023	0.172TrpTrp: 0.172 ± 0.011	0.373TrpTyr: 0.373 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.102TyrAla: 2.102 ± 0.051	0.476TyrCys: 0.476 ± 0.025	1.732TyrAsp: 1.732 ± 0.054	1.682TyrGlu: 1.682 ± 0.046	1.532TyrPhe: 1.532 ± 0.043	2.062TyrGly: 2.062 ± 0.044	0.687TyrHis: 0.687 ± 0.027	1.848TyrIle: 1.848 ± 0.041	1.466TyrLys: 1.466 ± 0.041	3.24TyrLeu: 3.24 ± 0.062	0.566TyrMet: 0.566 ± 0.021	1.255TyrAsn: 1.255 ± 0.037	1.426TyrPro: 1.426 ± 0.04	1.345TyrGln: 1.345 ± 0.035	1.905TyrArg: 1.905 ± 0.046	2.139TyrSer: 2.139 ± 0.048	1.765TyrThr: 1.765 ± 0.05	1.56TyrVal: 1.56 ± 0.042	0.37TyrTrp: 0.37 ± 0.021	1.135TyrTyr: 1.135 ± 0.039	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.001XaaGly: 0.001 ± 0.001	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.001XaaLeu: 0.001 ± 0.001	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.001	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.001XaaVal: 0.001 ± 0.001	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4071 proteins (1082977 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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