Amino acid dipepetide frequency for Sesbania mosaic virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.237AlaAla: 7.237 ± 1.034
1.974AlaCys: 1.974 ± 0.901
3.947AlaAsp: 3.947 ± 1.406
5.921AlaGlu: 5.921 ± 3.157
1.316AlaPhe: 1.316 ± 0.985
7.895AlaGly: 7.895 ± 2.52
1.316AlaHis: 1.316 ± 1.069
3.289AlaIle: 3.289 ± 1.603
5.921AlaLys: 5.921 ± 1.211
3.947AlaLeu: 3.947 ± 1.276
1.974AlaMet: 1.974 ± 1.105
3.289AlaAsn: 3.289 ± 1.12
5.263AlaPro: 5.263 ± 1.865
3.289AlaGln: 3.289 ± 0.718
3.289AlaArg: 3.289 ± 1.481
8.553AlaSer: 8.553 ± 2.191
6.579AlaThr: 6.579 ± 1.437
5.921AlaVal: 5.921 ± 2.076
1.316AlaTrp: 1.316 ± 0.432
0.658AlaTyr: 0.658 ± 0.493
0.0AlaXaa: 0.0 ± 0.0
Cys
2.632CysAla: 2.632 ± 0.983
1.974CysCys: 1.974 ± 1.478
0.658CysAsp: 0.658 ± 0.493
1.974CysGlu: 1.974 ± 2.125
1.974CysPhe: 1.974 ± 1.105
0.0CysGly: 0.0 ± 0.0
0.658CysHis: 0.658 ± 0.465
1.316CysIle: 1.316 ± 1.079
2.632CysLys: 2.632 ± 1.259
3.289CysLeu: 3.289 ± 0.88
0.0CysMet: 0.0 ± 0.0
1.316CysAsn: 1.316 ± 1.069
2.632CysPro: 2.632 ± 0.654
1.316CysGln: 1.316 ± 0.432
3.289CysArg: 3.289 ± 3.065
1.974CysSer: 1.974 ± 1.042
1.316CysThr: 1.316 ± 0.735
1.316CysVal: 1.316 ± 0.432
0.658CysTrp: 0.658 ± 0.493
1.974CysTyr: 1.974 ± 0.75
0.0CysXaa: 0.0 ± 0.0
Asp
1.974AspAla: 1.974 ± 0.802
1.974AspCys: 1.974 ± 1.222
1.316AspAsp: 1.316 ± 0.432
3.289AspGlu: 3.289 ± 1.869
0.658AspPhe: 0.658 ± 0.465
2.632AspGly: 2.632 ± 0.735
0.658AspHis: 0.658 ± 1.106
1.974AspIle: 1.974 ± 1.261
1.316AspLys: 1.316 ± 0.432
3.947AspLeu: 3.947 ± 1.653
0.658AspMet: 0.658 ± 0.694
0.0AspAsn: 0.0 ± 0.0
1.974AspPro: 1.974 ± 0.901
1.316AspGln: 1.316 ± 0.432
1.316AspArg: 1.316 ± 0.432
1.974AspSer: 1.974 ± 1.042
2.632AspThr: 2.632 ± 1.145
3.947AspVal: 3.947 ± 1.035
1.974AspTrp: 1.974 ± 0.802
2.632AspTyr: 2.632 ± 1.21
0.0AspXaa: 0.0 ± 0.0
Glu
5.921GluAla: 5.921 ± 2.272
0.658GluCys: 0.658 ± 1.106
5.921GluAsp: 5.921 ± 2.809
3.289GluGlu: 3.289 ± 1.933
3.289GluPhe: 3.289 ± 1.184
3.289GluGly: 3.289 ± 1.975
0.658GluHis: 0.658 ± 0.493
5.921GluIle: 5.921 ± 1.528
2.632GluLys: 2.632 ± 0.864
7.895GluLeu: 7.895 ± 2.487
0.658GluMet: 0.658 ± 0.493
1.974GluAsn: 1.974 ± 1.222
1.974GluPro: 1.974 ± 0.518
1.316GluGln: 1.316 ± 0.432
4.605GluArg: 4.605 ± 2.706
4.605GluSer: 4.605 ± 1.929
3.947GluThr: 3.947 ± 0.864
3.947GluVal: 3.947 ± 1.802
0.658GluTrp: 0.658 ± 0.493
0.658GluTyr: 0.658 ± 1.106
0.0GluXaa: 0.0 ± 0.0
Phe
3.289PheAla: 3.289 ± 1.615
1.316PheCys: 1.316 ± 0.985
3.289PheAsp: 3.289 ± 0.88
3.289PheGlu: 3.289 ± 1.268
0.658PhePhe: 0.658 ± 0.493
2.632PheGly: 2.632 ± 1.259
0.0PheHis: 0.0 ± 0.0
1.974PheIle: 1.974 ± 1.08
0.658PheLys: 0.658 ± 0.493
1.974PheLeu: 1.974 ± 0.901
0.658PheMet: 0.658 ± 0.493
1.316PheAsn: 1.316 ± 1.079
0.658PhePro: 0.658 ± 0.493
1.974PheGln: 1.974 ± 1.105
1.316PheArg: 1.316 ± 0.985
0.658PheSer: 0.658 ± 0.493
1.316PheThr: 1.316 ± 1.069
1.316PheVal: 1.316 ± 1.079
0.0PheTrp: 0.0 ± 0.0
1.974PheTyr: 1.974 ± 1.222
0.0PheXaa: 0.0 ± 0.0
Gly
2.632GlyAla: 2.632 ± 1.455
1.316GlyCys: 1.316 ± 0.432
3.947GlyAsp: 3.947 ± 1.604
3.289GlyGlu: 3.289 ± 1.915
3.947GlyPhe: 3.947 ± 0.464
3.289GlyGly: 3.289 ± 1.009
0.658GlyHis: 0.658 ± 0.493
1.974GlyIle: 1.974 ± 1.342
6.579GlyLys: 6.579 ± 1.702
2.632GlyLeu: 2.632 ± 0.808
1.316GlyMet: 1.316 ± 0.432
0.658GlyAsn: 0.658 ± 0.493
3.947GlyPro: 3.947 ± 1.007
1.974GlyGln: 1.974 ± 0.518
3.947GlyArg: 3.947 ± 1.115
8.553GlySer: 8.553 ± 1.833
2.632GlyThr: 2.632 ± 1.145
6.579GlyVal: 6.579 ± 2.504
1.974GlyTrp: 1.974 ± 0.802
2.632GlyTyr: 2.632 ± 0.735
0.0GlyXaa: 0.0 ± 0.0
His
1.974HisAla: 1.974 ± 0.901
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.658HisGlu: 0.658 ± 1.106
0.0HisPhe: 0.0 ± 0.0
0.658HisGly: 0.658 ± 0.493
0.658HisHis: 0.658 ± 0.465
0.0HisIle: 0.0 ± 0.0
0.658HisLys: 0.658 ± 0.493
0.658HisLeu: 0.658 ± 0.493
0.658HisMet: 0.658 ± 0.694
1.316HisAsn: 1.316 ± 1.069
0.658HisPro: 0.658 ± 0.465
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
2.632HisSer: 2.632 ± 0.735
1.316HisThr: 1.316 ± 1.069
3.947HisVal: 3.947 ± 1.499
0.658HisTrp: 0.658 ± 0.493
1.316HisTyr: 1.316 ± 0.985
0.0HisXaa: 0.0 ± 0.0
Ile
3.289IleAla: 3.289 ± 2.049
0.0IleCys: 0.0 ± 0.0
1.316IleAsp: 1.316 ± 1.069
3.947IleGlu: 3.947 ± 0.864
0.658IlePhe: 0.658 ± 0.493
3.947IleGly: 3.947 ± 0.464
1.316IleHis: 1.316 ± 0.735
1.316IleIle: 1.316 ± 1.069
1.974IleLys: 1.974 ± 1.222
1.974IleLeu: 1.974 ± 1.394
0.658IleMet: 0.658 ± 0.493
1.974IleAsn: 1.974 ± 0.518
3.289IlePro: 3.289 ± 0.718
0.658IleGln: 0.658 ± 0.694
3.289IleArg: 3.289 ± 1.481
3.947IleSer: 3.947 ± 1.035
1.316IleThr: 1.316 ± 0.693
1.974IleVal: 1.974 ± 1.08
0.0IleTrp: 0.0 ± 0.0
1.316IleTyr: 1.316 ± 0.693
0.0IleXaa: 0.0 ± 0.0
Lys
6.579LysAla: 6.579 ± 1.308
0.0LysCys: 0.0 ± 0.0
3.289LysAsp: 3.289 ± 1.736
1.316LysGlu: 1.316 ± 0.929
1.974LysPhe: 1.974 ± 1.261
1.316LysGly: 1.316 ± 0.929
0.658LysHis: 0.658 ± 0.493
1.974LysIle: 1.974 ± 0.75
3.289LysLys: 3.289 ± 0.718
5.921LysLeu: 5.921 ± 3.545
1.316LysMet: 1.316 ± 0.929
0.658LysAsn: 0.658 ± 1.106
3.947LysPro: 3.947 ± 1.604
3.289LysGln: 3.289 ± 1.009
1.974LysArg: 1.974 ± 0.518
4.605LysSer: 4.605 ± 1.91
2.632LysThr: 2.632 ± 0.654
1.974LysVal: 1.974 ± 2.128
1.316LysTrp: 1.316 ± 0.735
3.289LysTyr: 3.289 ± 0.79
0.0LysXaa: 0.0 ± 0.0
Leu
5.921LeuAla: 5.921 ± 0.578
2.632LeuCys: 2.632 ± 0.735
3.947LeuAsp: 3.947 ± 1.05
5.263LeuGlu: 5.263 ± 1.987
2.632LeuPhe: 2.632 ± 1.971
7.895LeuGly: 7.895 ± 2.253
1.316LeuHis: 1.316 ± 0.432
2.632LeuIle: 2.632 ± 1.259
2.632LeuLys: 2.632 ± 1.17
9.211LeuLeu: 9.211 ± 1.606
2.632LeuMet: 2.632 ± 1.17
3.947LeuAsn: 3.947 ± 1.694
4.605LeuPro: 4.605 ± 2.687
3.289LeuGln: 3.289 ± 1.14
5.921LeuArg: 5.921 ± 1.052
10.526LeuSer: 10.526 ± 2.451
1.974LeuThr: 1.974 ± 0.955
10.526LeuVal: 10.526 ± 1.041
1.316LeuTrp: 1.316 ± 0.432
1.316LeuTyr: 1.316 ± 0.432
0.0LeuXaa: 0.0 ± 0.0
Met
3.289MetAla: 3.289 ± 1.821
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
0.0MetGlu: 0.0 ± 0.0
0.658MetPhe: 0.658 ± 0.465
2.632MetGly: 2.632 ± 0.735
0.658MetHis: 0.658 ± 0.465
0.658MetIle: 0.658 ± 0.694
0.658MetLys: 0.658 ± 0.493
1.974MetLeu: 1.974 ± 0.75
0.658MetMet: 0.658 ± 0.465
0.658MetAsn: 0.658 ± 0.493
1.316MetPro: 1.316 ± 0.735
1.316MetGln: 1.316 ± 1.069
1.974MetArg: 1.974 ± 0.802
2.632MetSer: 2.632 ± 1.509
0.658MetThr: 0.658 ± 0.465
0.658MetVal: 0.658 ± 0.694
0.0MetTrp: 0.0 ± 0.0
0.658MetTyr: 0.658 ± 0.465
0.0MetXaa: 0.0 ± 0.0
Asn
1.316AsnAla: 1.316 ± 1.069
0.658AsnCys: 0.658 ± 0.465
0.658AsnAsp: 0.658 ± 1.106
1.974AsnGlu: 1.974 ± 0.75
0.0AsnPhe: 0.0 ± 0.0
1.316AsnGly: 1.316 ± 1.21
0.0AsnHis: 0.0 ± 0.0
1.316AsnIle: 1.316 ± 0.735
0.658AsnLys: 0.658 ± 0.493
3.289AsnLeu: 3.289 ± 0.654
1.974AsnMet: 1.974 ± 0.927
0.658AsnAsn: 0.658 ± 0.694
3.289AsnPro: 3.289 ± 1.009
1.974AsnGln: 1.974 ± 1.105
3.289AsnArg: 3.289 ± 0.654
2.632AsnSer: 2.632 ± 0.983
1.316AsnThr: 1.316 ± 0.735
0.658AsnVal: 0.658 ± 0.465
0.658AsnTrp: 0.658 ± 0.694
1.316AsnTyr: 1.316 ± 1.069
0.0AsnXaa: 0.0 ± 0.0
Pro
5.921ProAla: 5.921 ± 1.211
3.289ProCys: 3.289 ± 1.933
0.658ProAsp: 0.658 ± 0.493
6.579ProGlu: 6.579 ± 1.617
0.658ProPhe: 0.658 ± 0.465
3.289ProGly: 3.289 ± 1.736
1.974ProHis: 1.974 ± 1.478
0.0ProIle: 0.0 ± 0.0
3.289ProLys: 3.289 ± 1.009
5.921ProLeu: 5.921 ± 1.257
0.0ProMet: 0.0 ± 0.0
0.658ProAsn: 0.658 ± 0.465
7.237ProPro: 7.237 ± 3.692
1.316ProGln: 1.316 ± 0.735
1.316ProArg: 1.316 ± 1.079
10.526ProSer: 10.526 ± 3.435
6.579ProThr: 6.579 ± 1.47
4.605ProVal: 4.605 ± 0.488
0.658ProTrp: 0.658 ± 0.493
3.289ProTyr: 3.289 ± 1.206
0.0ProXaa: 0.0 ± 0.0
Gln
2.632GlnAla: 2.632 ± 1.21
0.0GlnCys: 0.0 ± 0.0
1.316GlnAsp: 1.316 ± 0.432
1.974GlnGlu: 1.974 ± 0.75
0.658GlnPhe: 0.658 ± 0.465
1.974GlnGly: 1.974 ± 0.518
0.658GlnHis: 0.658 ± 1.106
0.658GlnIle: 0.658 ± 0.465
1.316GlnLys: 1.316 ± 0.929
5.921GlnLeu: 5.921 ± 3.125
0.658GlnMet: 0.658 ± 0.694
1.316GlnAsn: 1.316 ± 0.985
2.632GlnPro: 2.632 ± 1.497
1.974GlnGln: 1.974 ± 1.307
1.974GlnArg: 1.974 ± 1.08
2.632GlnSer: 2.632 ± 1.17
1.974GlnThr: 1.974 ± 0.75
1.316GlnVal: 1.316 ± 0.693
0.0GlnTrp: 0.0 ± 0.0
1.316GlnTyr: 1.316 ± 0.693
0.0GlnXaa: 0.0 ± 0.0
Arg
5.921ArgAla: 5.921 ± 5.113
2.632ArgCys: 2.632 ± 1.455
0.0ArgAsp: 0.0 ± 0.0
3.289ArgGlu: 3.289 ± 1.268
1.974ArgPhe: 1.974 ± 1.478
4.605ArgGly: 4.605 ± 1.79
1.974ArgHis: 1.974 ± 1.261
3.947ArgIle: 3.947 ± 2.084
3.289ArgLys: 3.289 ± 1.933
5.263ArgLeu: 5.263 ± 1.471
0.658ArgMet: 0.658 ± 0.493
2.632ArgAsn: 2.632 ± 1.145
1.316ArgPro: 1.316 ± 0.929
1.316ArgGln: 1.316 ± 0.735
5.263ArgArg: 5.263 ± 2.533
3.289ArgSer: 3.289 ± 0.654
1.316ArgThr: 1.316 ± 0.432
5.263ArgVal: 5.263 ± 2.816
0.0ArgTrp: 0.0 ± 0.0
1.974ArgTyr: 1.974 ± 0.518
0.0ArgXaa: 0.0 ± 0.0
Ser
7.895SerAla: 7.895 ± 3.489
4.605SerCys: 4.605 ± 0.488
3.947SerAsp: 3.947 ± 0.864
5.921SerGlu: 5.921 ± 1.052
2.632SerPhe: 2.632 ± 0.944
7.895SerGly: 7.895 ± 0.435
1.316SerHis: 1.316 ± 0.432
2.632SerIle: 2.632 ± 1.387
5.263SerLys: 5.263 ± 1.672
8.553SerLeu: 8.553 ± 3.402
3.289SerMet: 3.289 ± 0.869
1.974SerAsn: 1.974 ± 0.955
7.895SerPro: 7.895 ± 2.592
2.632SerGln: 2.632 ± 1.17
5.921SerArg: 5.921 ± 1.492
15.132SerSer: 15.132 ± 3.875
6.579SerThr: 6.579 ± 2.24
6.579SerVal: 6.579 ± 1.579
3.289SerTrp: 3.289 ± 1.14
2.632SerTyr: 2.632 ± 0.944
0.0SerXaa: 0.0 ± 0.0
Thr
5.921ThrAla: 5.921 ± 3.34
1.316ThrCys: 1.316 ± 0.929
0.658ThrAsp: 0.658 ± 0.694
0.658ThrGlu: 0.658 ± 0.493
1.974ThrPhe: 1.974 ± 0.901
1.316ThrGly: 1.316 ± 1.069
1.974ThrHis: 1.974 ± 0.955
1.974ThrIle: 1.974 ± 1.08
1.974ThrLys: 1.974 ± 1.394
5.921ThrLeu: 5.921 ± 1.211
0.0ThrMet: 0.0 ± 0.0
1.974ThrAsn: 1.974 ± 1.478
6.579ThrPro: 6.579 ± 1.308
1.974ThrGln: 1.974 ± 0.518
1.316ThrArg: 1.316 ± 0.693
6.579ThrSer: 6.579 ± 0.348
3.947ThrThr: 3.947 ± 0.864
3.289ThrVal: 3.289 ± 1.821
1.316ThrTrp: 1.316 ± 0.693
1.316ThrTyr: 1.316 ± 1.387
0.0ThrXaa: 0.0 ± 0.0
Val
5.263ValAla: 5.263 ± 1.917
5.263ValCys: 5.263 ± 4.042
2.632ValAsp: 2.632 ± 0.735
7.237ValGlu: 7.237 ± 1.703
1.974ValPhe: 1.974 ± 1.261
5.263ValGly: 5.263 ± 1.917
0.658ValHis: 0.658 ± 0.465
2.632ValIle: 2.632 ± 0.654
3.947ValLys: 3.947 ± 1.007
4.605ValLeu: 4.605 ± 1.564
1.316ValMet: 1.316 ± 0.693
1.974ValAsn: 1.974 ± 1.307
4.605ValPro: 4.605 ± 1.172
1.974ValGln: 1.974 ± 0.518
5.921ValArg: 5.921 ± 1.456
5.921ValSer: 5.921 ± 2.979
1.316ValThr: 1.316 ± 0.735
3.947ValVal: 3.947 ± 0.901
3.289ValTrp: 3.289 ± 1.367
1.316ValTyr: 1.316 ± 1.069
0.0ValXaa: 0.0 ± 0.0
Trp
1.974TrpAla: 1.974 ± 0.802
1.316TrpCys: 1.316 ± 0.432
0.0TrpAsp: 0.0 ± 0.0
2.632TrpGlu: 2.632 ± 0.864
0.658TrpPhe: 0.658 ± 0.493
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.316TrpIle: 1.316 ± 0.929
0.658TrpLys: 0.658 ± 0.465
3.289TrpLeu: 3.289 ± 1.206
0.0TrpMet: 0.0 ± 0.0
0.658TrpAsn: 0.658 ± 0.493
1.974TrpPro: 1.974 ± 1.478
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
3.947TrpSer: 3.947 ± 1.035
0.0TrpThr: 0.0 ± 0.0
0.658TrpVal: 0.658 ± 0.493
0.0TrpTrp: 0.0 ± 0.0
0.658TrpTyr: 0.658 ± 0.694
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.316TyrAla: 1.316 ± 1.21
1.974TyrCys: 1.974 ± 1.042
0.658TyrAsp: 0.658 ± 0.694
1.316TyrGlu: 1.316 ± 0.432
1.974TyrPhe: 1.974 ± 2.125
2.632TyrGly: 2.632 ± 0.983
0.658TyrHis: 0.658 ± 0.465
0.658TyrIle: 0.658 ± 0.694
1.974TyrLys: 1.974 ± 0.518
3.947TyrLeu: 3.947 ± 1.296
1.316TyrMet: 1.316 ± 0.432
0.0TyrAsn: 0.0 ± 0.0
1.974TyrPro: 1.974 ± 1.042
0.0TyrGln: 0.0 ± 0.0
0.0TyrArg: 0.0 ± 0.0
5.921TyrSer: 5.921 ± 3.774
2.632TyrThr: 2.632 ± 1.974
2.632TyrVal: 2.632 ± 1.332
0.658TyrTrp: 0.658 ± 0.465
1.974TyrTyr: 1.974 ± 1.222
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1521 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski