Amino acid dipepetide frequency for Eel virus European X

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.338AlaAla: 3.338 ± 0.909
0.834AlaCys: 0.834 ± 0.488
2.503AlaAsp: 2.503 ± 0.675
2.782AlaGlu: 2.782 ± 0.65
0.834AlaPhe: 0.834 ± 0.496
3.616AlaGly: 3.616 ± 1.018
1.391AlaHis: 1.391 ± 0.645
3.894AlaIle: 3.894 ± 0.739
3.616AlaLys: 3.616 ± 2.09
5.563AlaLeu: 5.563 ± 1.155
2.503AlaMet: 2.503 ± 0.999
2.503AlaAsn: 2.503 ± 1.426
1.947AlaPro: 1.947 ± 0.694
3.616AlaGln: 3.616 ± 0.761
3.06AlaArg: 3.06 ± 0.736
3.338AlaSer: 3.338 ± 0.904
3.894AlaThr: 3.894 ± 0.577
2.503AlaVal: 2.503 ± 0.922
1.113AlaTrp: 1.113 ± 0.651
3.338AlaTyr: 3.338 ± 0.837
0.0AlaXaa: 0.0 ± 0.0
Cys
0.556CysAla: 0.556 ± 0.843
0.0CysCys: 0.0 ± 0.0
1.113CysAsp: 1.113 ± 0.552
0.278CysGlu: 0.278 ± 0.163
0.0CysPhe: 0.0 ± 0.0
0.556CysGly: 0.556 ± 0.276
0.278CysHis: 0.278 ± 0.163
0.278CysIle: 0.278 ± 0.336
0.834CysLys: 0.834 ± 0.593
2.503CysLeu: 2.503 ± 0.304
0.0CysMet: 0.0 ± 0.0
1.113CysAsn: 1.113 ± 0.651
1.391CysPro: 1.391 ± 0.833
0.278CysGln: 0.278 ± 0.336
0.556CysArg: 0.556 ± 0.276
0.834CysSer: 0.834 ± 0.593
0.556CysThr: 0.556 ± 0.276
1.391CysVal: 1.391 ± 0.814
1.113CysTrp: 1.113 ± 0.337
0.278CysTyr: 0.278 ± 0.494
0.0CysXaa: 0.0 ± 0.0
Asp
3.338AspAla: 3.338 ± 0.712
1.113AspCys: 1.113 ± 0.337
2.225AspAsp: 2.225 ± 0.697
4.451AspGlu: 4.451 ± 1.009
1.947AspPhe: 1.947 ± 0.54
3.338AspGly: 3.338 ± 0.987
1.669AspHis: 1.669 ± 0.479
2.782AspIle: 2.782 ± 0.936
3.338AspLys: 3.338 ± 1.277
6.398AspLeu: 6.398 ± 1.207
2.225AspMet: 2.225 ± 0.64
0.556AspAsn: 0.556 ± 0.325
2.225AspPro: 2.225 ± 0.608
1.391AspGln: 1.391 ± 0.7
2.782AspArg: 2.782 ± 0.939
3.616AspSer: 3.616 ± 0.54
2.503AspThr: 2.503 ± 0.865
2.225AspVal: 2.225 ± 0.697
1.947AspTrp: 1.947 ± 1.187
3.894AspTyr: 3.894 ± 0.836
0.0AspXaa: 0.0 ± 0.0
Glu
2.782GluAla: 2.782 ± 0.986
0.556GluCys: 0.556 ± 0.672
3.894GluAsp: 3.894 ± 0.739
5.841GluGlu: 5.841 ± 2.48
3.616GluPhe: 3.616 ± 1.149
3.338GluGly: 3.338 ± 1.112
1.947GluHis: 1.947 ± 0.704
5.563GluIle: 5.563 ± 1.24
3.616GluLys: 3.616 ± 1.726
6.12GluLeu: 6.12 ± 1.137
1.113GluMet: 1.113 ± 0.375
1.391GluAsn: 1.391 ± 0.323
2.225GluPro: 2.225 ± 1.248
1.669GluGln: 1.669 ± 0.815
3.894GluArg: 3.894 ± 0.905
6.954GluSer: 6.954 ± 2.306
4.451GluThr: 4.451 ± 1.968
3.338GluVal: 3.338 ± 1.041
1.113GluTrp: 1.113 ± 0.578
2.782GluTyr: 2.782 ± 1.098
0.0GluXaa: 0.0 ± 0.0
Phe
1.391PheAla: 1.391 ± 0.597
0.834PheCys: 0.834 ± 0.593
1.669PheAsp: 1.669 ± 0.952
1.947PheGlu: 1.947 ± 0.576
2.782PhePhe: 2.782 ± 1.306
1.391PheGly: 1.391 ± 0.433
1.391PheHis: 1.391 ± 0.814
0.0PheIle: 0.0 ± 0.0
3.616PheLys: 3.616 ± 0.622
4.451PheLeu: 4.451 ± 1.975
1.391PheMet: 1.391 ± 0.533
1.391PheAsn: 1.391 ± 0.455
1.947PhePro: 1.947 ± 0.523
4.729PheGln: 4.729 ± 1.608
2.225PheArg: 2.225 ± 0.987
2.503PheSer: 2.503 ± 0.622
1.669PheThr: 1.669 ± 1.105
2.503PheVal: 2.503 ± 0.595
0.556PheTrp: 0.556 ± 0.427
0.834PheTyr: 0.834 ± 0.873
0.0PheXaa: 0.0 ± 0.0
Gly
2.503GlyAla: 2.503 ± 0.692
0.556GlyCys: 0.556 ± 0.325
2.782GlyAsp: 2.782 ± 0.761
2.503GlyGlu: 2.503 ± 0.978
3.616GlyPhe: 3.616 ± 1.169
2.782GlyGly: 2.782 ± 0.604
0.834GlyHis: 0.834 ± 0.488
4.172GlyIle: 4.172 ± 0.95
4.729GlyLys: 4.729 ± 2.183
6.954GlyLeu: 6.954 ± 1.405
1.947GlyMet: 1.947 ± 1.184
2.782GlyAsn: 2.782 ± 0.961
2.503GlyPro: 2.503 ± 1.729
2.503GlyGln: 2.503 ± 0.877
1.947GlyArg: 1.947 ± 0.606
5.007GlySer: 5.007 ± 0.852
2.503GlyThr: 2.503 ± 0.772
3.616GlyVal: 3.616 ± 1.074
1.947GlyTrp: 1.947 ± 0.576
1.113GlyTyr: 1.113 ± 0.552
0.0GlyXaa: 0.0 ± 0.0
His
1.669HisAla: 1.669 ± 0.608
0.278HisCys: 0.278 ± 0.421
1.391HisAsp: 1.391 ± 0.645
0.556HisGlu: 0.556 ± 0.276
1.669HisPhe: 1.669 ± 0.385
0.556HisGly: 0.556 ± 0.987
1.113HisHis: 1.113 ± 0.447
2.503HisIle: 2.503 ± 0.595
1.113HisLys: 1.113 ± 0.424
2.782HisLeu: 2.782 ± 1.107
0.834HisMet: 0.834 ± 0.42
0.278HisAsn: 0.278 ± 0.163
2.225HisPro: 2.225 ± 0.804
2.225HisGln: 2.225 ± 0.636
1.669HisArg: 1.669 ± 0.708
1.391HisSer: 1.391 ± 0.533
0.556HisThr: 0.556 ± 0.325
1.113HisVal: 1.113 ± 0.651
0.834HisTrp: 0.834 ± 0.304
1.391HisTyr: 1.391 ± 0.586
0.0HisXaa: 0.0 ± 0.0
Ile
3.616IleAla: 3.616 ± 0.858
0.834IleCys: 0.834 ± 0.498
3.338IleAsp: 3.338 ± 0.782
5.285IleGlu: 5.285 ± 1.473
2.503IlePhe: 2.503 ± 1.029
4.451IleGly: 4.451 ± 1.241
1.113IleHis: 1.113 ± 0.489
2.225IleIle: 2.225 ± 0.368
4.172IleLys: 4.172 ± 0.99
5.841IleLeu: 5.841 ± 1.904
0.834IleMet: 0.834 ± 0.355
3.338IleAsn: 3.338 ± 0.638
2.503IlePro: 2.503 ± 1.141
3.616IleGln: 3.616 ± 1.116
3.616IleArg: 3.616 ± 1.349
3.616IleSer: 3.616 ± 1.301
3.338IleThr: 3.338 ± 1.354
2.225IleVal: 2.225 ± 0.518
0.834IleTrp: 0.834 ± 0.42
3.338IleTyr: 3.338 ± 0.965
0.0IleXaa: 0.0 ± 0.0
Lys
2.782LysAla: 2.782 ± 1.381
0.556LysCys: 0.556 ± 0.276
3.894LysAsp: 3.894 ± 0.812
5.563LysGlu: 5.563 ± 1.5
1.391LysPhe: 1.391 ± 0.844
4.729LysGly: 4.729 ± 1.018
1.113LysHis: 1.113 ± 0.434
3.06LysIle: 3.06 ± 1.03
6.12LysLys: 6.12 ± 2.279
6.12LysLeu: 6.12 ± 1.884
1.391LysMet: 1.391 ± 1.12
4.451LysAsn: 4.451 ± 1.783
1.669LysPro: 1.669 ± 1.022
2.503LysGln: 2.503 ± 1.001
3.338LysArg: 3.338 ± 0.619
5.563LysSer: 5.563 ± 1.839
3.616LysThr: 3.616 ± 1.189
3.338LysVal: 3.338 ± 0.405
2.503LysTrp: 2.503 ± 0.866
2.503LysTyr: 2.503 ± 1.279
0.0LysXaa: 0.0 ± 0.0
Leu
5.841LeuAla: 5.841 ± 1.611
0.834LeuCys: 0.834 ± 0.304
7.232LeuAsp: 7.232 ± 1.428
7.789LeuGlu: 7.789 ± 1.174
4.451LeuPhe: 4.451 ± 1.351
5.841LeuGly: 5.841 ± 0.962
1.113LeuHis: 1.113 ± 0.402
8.067LeuIle: 8.067 ± 2.084
3.06LeuLys: 3.06 ± 0.793
6.954LeuLeu: 6.954 ± 1.053
3.338LeuMet: 3.338 ± 0.809
3.616LeuAsn: 3.616 ± 1.109
4.172LeuPro: 4.172 ± 1.037
3.338LeuGln: 3.338 ± 0.856
7.51LeuArg: 7.51 ± 1.063
10.014LeuSer: 10.014 ± 0.72
6.398LeuThr: 6.398 ± 1.094
6.398LeuVal: 6.398 ± 2.122
0.834LeuTrp: 0.834 ± 0.304
1.113LeuTyr: 1.113 ± 0.337
0.0LeuXaa: 0.0 ± 0.0
Met
1.947MetAla: 1.947 ± 1.187
0.278MetCys: 0.278 ± 0.421
2.225MetAsp: 2.225 ± 0.673
1.669MetGlu: 1.669 ± 1.305
1.391MetPhe: 1.391 ± 0.497
1.947MetGly: 1.947 ± 0.763
0.278MetHis: 0.278 ± 0.163
0.834MetIle: 0.834 ± 0.304
0.556MetLys: 0.556 ± 0.435
1.391MetLeu: 1.391 ± 1.002
1.669MetMet: 1.669 ± 0.634
0.834MetAsn: 0.834 ± 0.355
0.834MetPro: 0.834 ± 0.42
1.113MetGln: 1.113 ± 0.605
2.503MetArg: 2.503 ± 0.813
3.06MetSer: 3.06 ± 1.179
2.782MetThr: 2.782 ± 0.678
1.669MetVal: 1.669 ± 1.443
0.278MetTrp: 0.278 ± 0.163
0.556MetTyr: 0.556 ± 0.276
0.0MetXaa: 0.0 ± 0.0
Asn
2.782AsnAla: 2.782 ± 0.849
0.278AsnCys: 0.278 ± 0.336
0.834AsnAsp: 0.834 ± 0.355
1.391AsnGlu: 1.391 ± 1.577
1.391AsnPhe: 1.391 ± 0.814
3.894AsnGly: 3.894 ± 0.834
2.225AsnHis: 2.225 ± 0.627
3.338AsnIle: 3.338 ± 0.98
3.06AsnLys: 3.06 ± 1.219
4.729AsnLeu: 4.729 ± 0.779
1.391AsnMet: 1.391 ± 0.802
3.616AsnAsn: 3.616 ± 0.929
3.894AsnPro: 3.894 ± 0.577
3.338AsnGln: 3.338 ± 0.599
1.391AsnArg: 1.391 ± 0.533
2.782AsnSer: 2.782 ± 1.381
0.834AsnThr: 0.834 ± 0.304
1.947AsnVal: 1.947 ± 0.662
1.391AsnTrp: 1.391 ± 0.814
0.834AsnTyr: 0.834 ± 0.355
0.0AsnXaa: 0.0 ± 0.0
Pro
2.225ProAla: 2.225 ± 1.026
0.278ProCys: 0.278 ± 0.163
1.669ProAsp: 1.669 ± 0.721
5.007ProGlu: 5.007 ± 1.541
2.225ProPhe: 2.225 ± 0.948
1.669ProGly: 1.669 ± 0.932
2.225ProHis: 2.225 ± 1.129
2.503ProIle: 2.503 ± 0.861
3.616ProLys: 3.616 ± 1.769
4.729ProLeu: 4.729 ± 1.751
0.0ProMet: 0.0 ± 0.392
1.391ProAsn: 1.391 ± 0.7
1.113ProPro: 1.113 ± 0.87
1.113ProGln: 1.113 ± 0.693
1.113ProArg: 1.113 ± 0.744
4.729ProSer: 4.729 ± 0.807
4.451ProThr: 4.451 ± 1.248
2.503ProVal: 2.503 ± 1.166
0.278ProTrp: 0.278 ± 0.163
1.947ProTyr: 1.947 ± 1.57
0.0ProXaa: 0.0 ± 0.0
Gln
2.782GlnAla: 2.782 ± 2.283
0.834GlnCys: 0.834 ± 0.433
3.894GlnAsp: 3.894 ± 1.654
2.225GlnGlu: 2.225 ± 0.873
1.391GlnPhe: 1.391 ± 1.152
3.338GlnGly: 3.338 ± 0.768
0.834GlnHis: 0.834 ± 0.488
1.947GlnIle: 1.947 ± 0.485
3.338GlnLys: 3.338 ± 0.991
3.894GlnLeu: 3.894 ± 0.701
1.113GlnMet: 1.113 ± 0.625
2.503GlnAsn: 2.503 ± 1.146
0.834GlnPro: 0.834 ± 0.44
0.834GlnGln: 0.834 ± 0.304
1.947GlnArg: 1.947 ± 0.74
3.616GlnSer: 3.616 ± 2.115
1.947GlnThr: 1.947 ± 0.829
3.894GlnVal: 3.894 ± 1.191
0.278GlnTrp: 0.278 ± 0.336
1.391GlnTyr: 1.391 ± 0.586
0.0GlnXaa: 0.0 ± 0.0
Arg
3.338ArgAla: 3.338 ± 1.071
0.834ArgCys: 0.834 ± 0.488
1.669ArgAsp: 1.669 ± 0.608
3.616ArgGlu: 3.616 ± 0.818
2.225ArgPhe: 2.225 ± 0.984
3.06ArgGly: 3.06 ± 1.05
1.947ArgHis: 1.947 ± 0.765
1.947ArgIle: 1.947 ± 1.1
3.338ArgLys: 3.338 ± 1.492
4.172ArgLeu: 4.172 ± 0.559
1.669ArgMet: 1.669 ± 0.71
3.338ArgAsn: 3.338 ± 0.963
2.225ArgPro: 2.225 ± 0.816
2.225ArgGln: 2.225 ± 0.987
3.06ArgArg: 3.06 ± 0.674
5.841ArgSer: 5.841 ± 0.835
1.669ArgThr: 1.669 ± 0.721
3.06ArgVal: 3.06 ± 1.075
1.113ArgTrp: 1.113 ± 0.402
0.556ArgTyr: 0.556 ± 0.669
0.0ArgXaa: 0.0 ± 0.0
Ser
7.789SerAla: 7.789 ± 1.4
1.113SerCys: 1.113 ± 0.402
7.232SerAsp: 7.232 ± 1.426
4.729SerGlu: 4.729 ± 0.7
3.338SerPhe: 3.338 ± 0.877
2.782SerGly: 2.782 ± 0.555
3.616SerHis: 3.616 ± 1.33
6.676SerIle: 6.676 ± 0.935
6.12SerLys: 6.12 ± 1.319
8.345SerLeu: 8.345 ± 2.657
1.947SerMet: 1.947 ± 0.825
3.616SerAsn: 3.616 ± 1.712
4.451SerPro: 4.451 ± 0.994
2.782SerGln: 2.782 ± 1.564
2.782SerArg: 2.782 ± 0.957
8.345SerSer: 8.345 ± 1.786
3.894SerThr: 3.894 ± 0.969
5.285SerVal: 5.285 ± 2.177
1.391SerTrp: 1.391 ± 0.844
1.669SerTyr: 1.669 ± 0.728
0.0SerXaa: 0.0 ± 0.0
Thr
1.669ThrAla: 1.669 ± 0.668
1.391ThrCys: 1.391 ± 0.433
2.225ThrAsp: 2.225 ± 0.656
5.563ThrGlu: 5.563 ± 1.596
1.391ThrPhe: 1.391 ± 0.323
3.616ThrGly: 3.616 ± 1.004
1.391ThrHis: 1.391 ± 0.323
2.782ThrIle: 2.782 ± 0.993
3.06ThrLys: 3.06 ± 1.459
5.563ThrLeu: 5.563 ± 1.418
0.556ThrMet: 0.556 ± 0.325
3.06ThrAsn: 3.06 ± 0.869
3.338ThrPro: 3.338 ± 2.407
1.947ThrGln: 1.947 ± 0.88
2.782ThrArg: 2.782 ± 1.215
5.007ThrSer: 5.007 ± 0.835
4.451ThrThr: 4.451 ± 0.851
3.06ThrVal: 3.06 ± 0.528
1.113ThrTrp: 1.113 ± 0.489
1.669ThrTyr: 1.669 ± 0.589
0.0ThrXaa: 0.0 ± 0.0
Val
2.225ValAla: 2.225 ± 1.937
1.947ValCys: 1.947 ± 0.943
2.503ValAsp: 2.503 ± 1.349
2.782ValGlu: 2.782 ± 1.023
1.669ValPhe: 1.669 ± 0.932
3.06ValGly: 3.06 ± 0.778
0.556ValHis: 0.556 ± 0.672
4.729ValIle: 4.729 ± 1.286
4.451ValLys: 4.451 ± 0.583
4.172ValLeu: 4.172 ± 1.129
1.391ValMet: 1.391 ± 0.879
2.225ValAsn: 2.225 ± 0.518
3.06ValPro: 3.06 ± 1.05
2.225ValGln: 2.225 ± 0.627
2.225ValArg: 2.225 ± 0.97
6.398ValSer: 6.398 ± 1.225
3.616ValThr: 3.616 ± 0.772
2.782ValVal: 2.782 ± 0.904
0.834ValTrp: 0.834 ± 0.593
1.947ValTyr: 1.947 ± 0.577
0.0ValXaa: 0.0 ± 0.0
Trp
2.225TrpAla: 2.225 ± 1.524
0.0TrpCys: 0.0 ± 0.0
0.556TrpAsp: 0.556 ± 0.325
0.834TrpGlu: 0.834 ± 0.488
0.278TrpPhe: 0.278 ± 0.163
1.947TrpGly: 1.947 ± 0.346
0.278TrpHis: 0.278 ± 0.163
1.391TrpIle: 1.391 ± 0.863
1.669TrpLys: 1.669 ± 0.668
1.113TrpLeu: 1.113 ± 0.337
0.834TrpMet: 0.834 ± 1.03
1.391TrpAsn: 1.391 ± 0.557
0.834TrpPro: 0.834 ± 0.488
0.0TrpGln: 0.0 ± 0.0
0.834TrpArg: 0.834 ± 0.304
2.782TrpSer: 2.782 ± 0.394
1.391TrpThr: 1.391 ± 0.586
0.834TrpVal: 0.834 ± 0.873
0.278TrpTrp: 0.278 ± 0.163
0.278TrpTyr: 0.278 ± 0.336
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.391TyrAla: 1.391 ± 0.535
0.556TyrCys: 0.556 ± 0.598
1.113TyrAsp: 1.113 ± 0.651
1.391TyrGlu: 1.391 ± 0.586
1.113TyrPhe: 1.113 ± 0.651
1.391TyrGly: 1.391 ± 0.645
0.834TyrHis: 0.834 ± 0.766
1.947TyrIle: 1.947 ± 0.949
2.782TyrLys: 2.782 ± 1.071
6.12TyrLeu: 6.12 ± 1.897
1.391TyrMet: 1.391 ± 0.881
1.947TyrAsn: 1.947 ± 0.513
1.669TyrPro: 1.669 ± 0.668
1.391TyrGln: 1.391 ± 0.803
1.669TyrArg: 1.669 ± 0.875
2.503TyrSer: 2.503 ± 0.675
1.113TyrThr: 1.113 ± 1.255
1.113TyrVal: 1.113 ± 0.673
0.0TyrTrp: 0.0 ± 0.0
1.113TyrTyr: 1.113 ± 0.795
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (3596 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski