Amino acid dipepetide frequency for Pudu puda papillomavirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.893AlaAla: 4.893 ± 1.871
0.445AlaCys: 0.445 ± 0.396
2.669AlaAsp: 2.669 ± 1.173
4.893AlaGlu: 4.893 ± 1.577
3.114AlaPhe: 3.114 ± 0.76
4.448AlaGly: 4.448 ± 0.993
0.0AlaHis: 0.0 ± 0.0
1.335AlaIle: 1.335 ± 0.712
2.669AlaLys: 2.669 ± 1.198
4.448AlaLeu: 4.448 ± 0.926
0.89AlaMet: 0.89 ± 0.41
2.224AlaAsn: 2.224 ± 0.785
3.559AlaPro: 3.559 ± 1.817
2.224AlaGln: 2.224 ± 0.967
2.669AlaArg: 2.669 ± 1.555
3.559AlaSer: 3.559 ± 0.97
6.673AlaThr: 6.673 ± 1.112
1.779AlaVal: 1.779 ± 0.596
2.224AlaTrp: 2.224 ± 1.021
0.445AlaTyr: 0.445 ± 0.396
0.0AlaXaa: 0.0 ± 0.0
Cys
0.89CysAla: 0.89 ± 0.415
0.89CysCys: 0.89 ± 1.095
0.445CysAsp: 0.445 ± 0.547
0.0CysGlu: 0.0 ± 0.0
0.445CysPhe: 0.445 ± 0.436
1.779CysGly: 1.779 ± 1.221
0.89CysHis: 0.89 ± 1.127
1.335CysIle: 1.335 ± 1.066
1.779CysLys: 1.779 ± 0.83
1.335CysLeu: 1.335 ± 0.643
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
2.669CysPro: 2.669 ± 1.182
1.335CysGln: 1.335 ± 0.606
2.669CysArg: 2.669 ± 1.565
0.89CysSer: 0.89 ± 0.575
2.224CysThr: 2.224 ± 1.572
0.445CysVal: 0.445 ± 0.547
0.89CysTrp: 0.89 ± 0.415
0.89CysTyr: 0.89 ± 0.688
0.0CysXaa: 0.0 ± 0.0
Asp
4.448AspAla: 4.448 ± 0.946
2.224AspCys: 2.224 ± 0.624
3.114AspAsp: 3.114 ± 1.183
0.89AspGlu: 0.89 ± 0.648
2.224AspPhe: 2.224 ± 0.506
3.559AspGly: 3.559 ± 1.385
0.445AspHis: 0.445 ± 0.368
4.004AspIle: 4.004 ± 1.007
1.779AspLys: 1.779 ± 0.717
8.452AspLeu: 8.452 ± 2.267
0.89AspMet: 0.89 ± 0.415
3.114AspAsn: 3.114 ± 0.834
3.559AspPro: 3.559 ± 1.767
2.224AspGln: 2.224 ± 0.466
1.335AspArg: 1.335 ± 0.776
4.893AspSer: 4.893 ± 0.92
4.448AspThr: 4.448 ± 1.362
3.114AspVal: 3.114 ± 0.687
0.89AspTrp: 0.89 ± 0.707
2.224AspTyr: 2.224 ± 0.785
0.0AspXaa: 0.0 ± 0.0
Glu
3.114GluAla: 3.114 ± 1.238
0.445GluCys: 0.445 ± 0.547
5.783GluAsp: 5.783 ± 0.729
12.011GluGlu: 12.011 ± 2.74
3.114GluPhe: 3.114 ± 0.768
3.114GluGly: 3.114 ± 1.551
1.335GluHis: 1.335 ± 0.448
3.559GluIle: 3.559 ± 1.053
3.114GluLys: 3.114 ± 0.93
5.338GluLeu: 5.338 ± 0.467
1.335GluMet: 1.335 ± 0.429
3.114GluAsn: 3.114 ± 1.875
3.559GluPro: 3.559 ± 1.339
3.559GluGln: 3.559 ± 1.518
1.779GluArg: 1.779 ± 0.581
3.114GluSer: 3.114 ± 0.687
4.448GluThr: 4.448 ± 1.334
6.228GluVal: 6.228 ± 1.588
0.89GluTrp: 0.89 ± 0.473
0.89GluTyr: 0.89 ± 0.415
0.0GluXaa: 0.0 ± 0.0
Phe
1.779PheAla: 1.779 ± 0.646
0.445PheCys: 0.445 ± 0.547
2.669PheAsp: 2.669 ± 0.91
4.004PheGlu: 4.004 ± 0.731
2.224PhePhe: 2.224 ± 1.01
2.224PheGly: 2.224 ± 1.26
1.335PheHis: 1.335 ± 0.606
2.224PheIle: 2.224 ± 0.791
3.559PheLys: 3.559 ± 1.037
4.448PheLeu: 4.448 ± 1.498
0.445PheMet: 0.445 ± 0.354
3.114PheAsn: 3.114 ± 0.438
0.89PhePro: 0.89 ± 0.707
1.779PheGln: 1.779 ± 0.848
1.335PheArg: 1.335 ± 0.383
5.338PheSer: 5.338 ± 0.95
1.335PheThr: 1.335 ± 0.662
0.89PheVal: 0.89 ± 0.46
1.335PheTrp: 1.335 ± 0.662
2.224PheTyr: 2.224 ± 1.141
0.0PheXaa: 0.0 ± 0.0
Gly
2.669GlyAla: 2.669 ± 1.173
1.335GlyCys: 1.335 ± 0.927
6.228GlyAsp: 6.228 ± 1.848
5.338GlyGlu: 5.338 ± 1.371
0.89GlyPhe: 0.89 ± 0.46
7.117GlyGly: 7.117 ± 2.596
3.559GlyHis: 3.559 ± 0.588
3.559GlyIle: 3.559 ± 0.783
1.335GlyLys: 1.335 ± 0.662
4.893GlyLeu: 4.893 ± 1.511
0.445GlyMet: 0.445 ± 0.396
2.224GlyAsn: 2.224 ± 0.694
2.669GlyPro: 2.669 ± 0.456
2.224GlyGln: 2.224 ± 0.822
7.117GlyArg: 7.117 ± 1.981
5.338GlySer: 5.338 ± 1.2
6.673GlyThr: 6.673 ± 1.572
3.114GlyVal: 3.114 ± 1.226
0.89GlyTrp: 0.89 ± 1.095
1.335GlyTyr: 1.335 ± 0.704
0.0GlyXaa: 0.0 ± 0.0
His
0.89HisAla: 0.89 ± 0.415
0.445HisCys: 0.445 ± 0.564
0.89HisAsp: 0.89 ± 0.575
0.445HisGlu: 0.445 ± 0.564
1.779HisPhe: 1.779 ± 0.596
0.89HisGly: 0.89 ± 0.481
0.0HisHis: 0.0 ± 0.0
0.445HisIle: 0.445 ± 0.368
0.445HisLys: 0.445 ± 0.564
0.445HisLeu: 0.445 ± 0.396
0.89HisMet: 0.89 ± 0.691
1.335HisAsn: 1.335 ± 0.676
0.89HisPro: 0.89 ± 0.46
1.335HisGln: 1.335 ± 0.662
1.335HisArg: 1.335 ± 0.698
0.89HisSer: 0.89 ± 0.645
1.779HisThr: 1.779 ± 0.626
1.335HisVal: 1.335 ± 0.839
1.335HisTrp: 1.335 ± 0.404
0.445HisTyr: 0.445 ± 0.436
0.0HisXaa: 0.0 ± 0.0
Ile
2.669IleAla: 2.669 ± 1.273
1.779IleCys: 1.779 ± 0.851
3.559IleAsp: 3.559 ± 1.094
3.559IleGlu: 3.559 ± 1.115
1.335IlePhe: 1.335 ± 0.698
4.893IleGly: 4.893 ± 2.242
0.0IleHis: 0.0 ± 0.0
1.335IleIle: 1.335 ± 0.383
3.114IleLys: 3.114 ± 0.454
1.335IleLeu: 1.335 ± 0.383
0.445IleMet: 0.445 ± 0.37
1.335IleAsn: 1.335 ± 0.429
2.669IlePro: 2.669 ± 0.767
0.445IleGln: 0.445 ± 0.368
2.669IleArg: 2.669 ± 1.025
3.114IleSer: 3.114 ± 0.852
2.224IleThr: 2.224 ± 0.709
4.448IleVal: 4.448 ± 1.012
0.445IleTrp: 0.445 ± 0.547
3.559IleTyr: 3.559 ± 1.26
0.0IleXaa: 0.0 ± 0.0
Lys
2.224LysAla: 2.224 ± 0.791
1.779LysCys: 1.779 ± 0.581
1.335LysAsp: 1.335 ± 0.729
2.224LysGlu: 2.224 ± 0.694
3.559LysPhe: 3.559 ± 1.264
2.224LysGly: 2.224 ± 0.853
1.779LysHis: 1.779 ± 0.991
2.224LysIle: 2.224 ± 0.958
3.559LysLys: 3.559 ± 0.518
2.669LysLeu: 2.669 ± 1.547
0.89LysMet: 0.89 ± 0.597
3.114LysAsn: 3.114 ± 1.076
1.779LysPro: 1.779 ± 0.646
1.779LysGln: 1.779 ± 0.581
5.338LysArg: 5.338 ± 0.913
4.448LysSer: 4.448 ± 1.304
1.779LysThr: 1.779 ± 0.622
3.114LysVal: 3.114 ± 1.441
1.335LysTrp: 1.335 ± 0.689
2.224LysTyr: 2.224 ± 0.873
0.0LysXaa: 0.0 ± 0.0
Leu
4.448LeuAla: 4.448 ± 0.79
1.779LeuCys: 1.779 ± 0.917
6.673LeuAsp: 6.673 ± 0.79
4.004LeuGlu: 4.004 ± 1.993
5.338LeuPhe: 5.338 ± 0.803
5.783LeuGly: 5.783 ± 1.44
1.335LeuHis: 1.335 ± 0.698
3.559LeuIle: 3.559 ± 0.982
7.562LeuLys: 7.562 ± 1.631
10.231LeuLeu: 10.231 ± 2.537
1.779LeuMet: 1.779 ± 0.776
1.335LeuAsn: 1.335 ± 1.061
3.559LeuPro: 3.559 ± 1.484
8.007LeuGln: 8.007 ± 1.497
4.893LeuArg: 4.893 ± 1.277
5.783LeuSer: 5.783 ± 1.454
6.228LeuThr: 6.228 ± 0.707
3.114LeuVal: 3.114 ± 1.079
1.335LeuTrp: 1.335 ± 0.585
3.114LeuTyr: 3.114 ± 0.547
0.0LeuXaa: 0.0 ± 0.0
Met
1.779MetAla: 1.779 ± 0.717
0.89MetCys: 0.89 ± 0.707
1.779MetAsp: 1.779 ± 1.583
0.445MetGlu: 0.445 ± 0.436
0.89MetPhe: 0.89 ± 0.707
0.445MetGly: 0.445 ± 0.368
0.0MetHis: 0.0 ± 0.0
0.445MetIle: 0.445 ± 0.368
0.445MetLys: 0.445 ± 0.354
1.779MetLeu: 1.779 ± 0.991
0.445MetMet: 0.445 ± 0.396
0.445MetAsn: 0.445 ± 0.396
0.0MetPro: 0.0 ± 0.0
0.445MetGln: 0.445 ± 0.354
0.89MetArg: 0.89 ± 0.707
1.335MetSer: 1.335 ± 0.585
0.89MetThr: 0.89 ± 0.707
1.779MetVal: 1.779 ± 0.622
0.0MetTrp: 0.0 ± 0.0
0.89MetTyr: 0.89 ± 0.791
0.0MetXaa: 0.0 ± 0.0
Asn
2.669AsnAla: 2.669 ± 1.022
0.89AsnCys: 0.89 ± 0.473
1.335AsnAsp: 1.335 ± 0.712
3.559AsnGlu: 3.559 ± 1.046
2.224AsnPhe: 2.224 ± 1.215
2.224AsnGly: 2.224 ± 0.423
0.445AsnHis: 0.445 ± 0.354
2.224AsnIle: 2.224 ± 1.141
2.669AsnLys: 2.669 ± 1.388
1.779AsnLeu: 1.779 ± 0.696
1.335AsnMet: 1.335 ± 0.662
2.669AsnAsn: 2.669 ± 1.02
3.114AsnPro: 3.114 ± 1.617
2.224AsnGln: 2.224 ± 0.694
2.669AsnArg: 2.669 ± 0.562
2.669AsnSer: 2.669 ± 0.974
2.669AsnThr: 2.669 ± 0.615
0.89AsnVal: 0.89 ± 0.707
0.445AsnTrp: 0.445 ± 0.354
0.445AsnTyr: 0.445 ± 0.368
0.0AsnXaa: 0.0 ± 0.0
Pro
3.114ProAla: 3.114 ± 0.741
0.89ProCys: 0.89 ± 1.127
4.448ProAsp: 4.448 ± 2.135
4.448ProGlu: 4.448 ± 1.337
0.89ProPhe: 0.89 ± 0.575
3.114ProGly: 3.114 ± 1.79
0.0ProHis: 0.0 ± 0.0
1.779ProIle: 1.779 ± 0.21
3.114ProLys: 3.114 ± 0.438
4.448ProLeu: 4.448 ± 0.79
0.89ProMet: 0.89 ± 0.415
4.004ProAsn: 4.004 ± 1.571
8.452ProPro: 8.452 ± 1.103
1.335ProGln: 1.335 ± 0.776
3.559ProArg: 3.559 ± 1.354
4.893ProSer: 4.893 ± 0.901
3.114ProThr: 3.114 ± 1.518
4.448ProVal: 4.448 ± 1.024
0.0ProTrp: 0.0 ± 0.0
2.669ProTyr: 2.669 ± 1.112
0.0ProXaa: 0.0 ± 0.0
Gln
1.335GlnAla: 1.335 ± 0.383
1.779GlnCys: 1.779 ± 1.3
1.335GlnAsp: 1.335 ± 1.104
4.448GlnGlu: 4.448 ± 1.044
1.779GlnPhe: 1.779 ± 1.265
5.783GlnGly: 5.783 ± 1.771
0.89GlnHis: 0.89 ± 0.424
0.89GlnIle: 0.89 ± 0.473
0.445GlnLys: 0.445 ± 0.436
6.228GlnLeu: 6.228 ± 1.74
1.335GlnMet: 1.335 ± 0.729
1.335GlnAsn: 1.335 ± 0.662
1.335GlnPro: 1.335 ± 0.711
4.448GlnGln: 4.448 ± 2.554
3.114GlnArg: 3.114 ± 1.725
2.669GlnSer: 2.669 ± 0.537
5.338GlnThr: 5.338 ± 1.156
3.559GlnVal: 3.559 ± 0.42
0.445GlnTrp: 0.445 ± 0.354
2.669GlnTyr: 2.669 ± 0.448
0.0GlnXaa: 0.0 ± 0.0
Arg
3.559ArgAla: 3.559 ± 0.739
2.224ArgCys: 2.224 ± 1.623
0.445ArgAsp: 0.445 ± 0.436
3.114ArgGlu: 3.114 ± 1.238
2.669ArgPhe: 2.669 ± 0.456
4.004ArgGly: 4.004 ± 1.507
1.335ArgHis: 1.335 ± 0.776
2.669ArgIle: 2.669 ± 1.014
4.893ArgLys: 4.893 ± 1.108
7.562ArgLeu: 7.562 ± 1.799
0.445ArgMet: 0.445 ± 0.354
1.335ArgAsn: 1.335 ± 0.643
3.114ArgPro: 3.114 ± 2.121
4.004ArgGln: 4.004 ± 0.736
9.786ArgArg: 9.786 ± 2.802
5.338ArgSer: 5.338 ± 1.258
3.114ArgThr: 3.114 ± 1.522
2.224ArgVal: 2.224 ± 1.403
0.445ArgTrp: 0.445 ± 0.547
2.224ArgTyr: 2.224 ± 1.302
0.0ArgXaa: 0.0 ± 0.0
Ser
5.338SerAla: 5.338 ± 1.482
0.89SerCys: 0.89 ± 0.61
4.893SerAsp: 4.893 ± 1.605
4.448SerGlu: 4.448 ± 1.148
4.448SerPhe: 4.448 ± 1.879
2.224SerGly: 2.224 ± 0.953
1.335SerHis: 1.335 ± 0.711
4.004SerIle: 4.004 ± 1.565
1.335SerLys: 1.335 ± 1.187
9.342SerLeu: 9.342 ± 1.64
1.335SerMet: 1.335 ± 0.404
2.224SerAsn: 2.224 ± 0.853
5.338SerPro: 5.338 ± 1.959
4.004SerGln: 4.004 ± 1.507
4.893SerArg: 4.893 ± 1.197
8.007SerSer: 8.007 ± 2.067
5.783SerThr: 5.783 ± 1.408
3.559SerVal: 3.559 ± 1.354
1.335SerTrp: 1.335 ± 1.308
1.335SerTyr: 1.335 ± 0.733
0.0SerXaa: 0.0 ± 0.0
Thr
4.004ThrAla: 4.004 ± 0.902
0.445ThrCys: 0.445 ± 0.354
4.448ThrAsp: 4.448 ± 0.715
2.669ThrGlu: 2.669 ± 1.378
2.224ThrPhe: 2.224 ± 0.953
7.562ThrGly: 7.562 ± 1.948
1.335ThrHis: 1.335 ± 0.873
3.114ThrIle: 3.114 ± 1.209
2.224ThrLys: 2.224 ± 0.466
8.452ThrLeu: 8.452 ± 1.956
1.335ThrMet: 1.335 ± 0.728
2.669ThrAsn: 2.669 ± 0.91
5.783ThrPro: 5.783 ± 1.579
4.893ThrGln: 4.893 ± 0.893
2.669ThrArg: 2.669 ± 1.051
3.114ThrSer: 3.114 ± 1.223
2.224ThrThr: 2.224 ± 0.371
6.673ThrVal: 6.673 ± 1.36
1.335ThrTrp: 1.335 ± 0.841
0.89ThrTyr: 0.89 ± 0.707
0.0ThrXaa: 0.0 ± 0.0
Val
3.559ValAla: 3.559 ± 1.024
1.335ValCys: 1.335 ± 0.585
2.669ValAsp: 2.669 ± 0.93
4.004ValGlu: 4.004 ± 0.73
2.669ValPhe: 2.669 ± 1.136
3.114ValGly: 3.114 ± 0.834
1.335ValHis: 1.335 ± 0.737
3.559ValIle: 3.559 ± 1.253
3.114ValLys: 3.114 ± 1.031
3.559ValLeu: 3.559 ± 1.715
0.0ValMet: 0.0 ± 0.324
2.224ValAsn: 2.224 ± 1.01
4.448ValPro: 4.448 ± 1.531
2.224ValGln: 2.224 ± 1.079
2.224ValArg: 2.224 ± 0.442
6.228ValSer: 6.228 ± 0.841
4.004ValThr: 4.004 ± 1.99
2.669ValVal: 2.669 ± 1.213
0.445ValTrp: 0.445 ± 0.396
1.779ValTyr: 1.779 ± 1.01
0.0ValXaa: 0.0 ± 0.0
Trp
0.445TrpAla: 0.445 ± 0.354
0.445TrpCys: 0.445 ± 0.547
1.335TrpAsp: 1.335 ± 0.783
1.779TrpGlu: 1.779 ± 0.979
1.335TrpPhe: 1.335 ± 1.061
1.779TrpGly: 1.779 ± 1.142
0.0TrpHis: 0.0 ± 0.0
0.89TrpIle: 0.89 ± 0.415
1.779TrpLys: 1.779 ± 1.15
0.89TrpLeu: 0.89 ± 0.707
0.445TrpMet: 0.445 ± 0.354
1.335TrpAsn: 1.335 ± 0.698
0.445TrpPro: 0.445 ± 0.547
0.0TrpGln: 0.0 ± 0.0
0.445TrpArg: 0.445 ± 0.354
1.335TrpSer: 1.335 ± 0.841
1.335TrpThr: 1.335 ± 0.838
1.335TrpVal: 1.335 ± 0.404
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.335TyrAla: 1.335 ± 1.061
0.445TyrCys: 0.445 ± 0.354
1.779TyrAsp: 1.779 ± 0.658
3.559TyrGlu: 3.559 ± 0.889
0.445TyrPhe: 0.445 ± 0.354
2.669TyrGly: 2.669 ± 0.422
0.89TyrHis: 0.89 ± 0.46
1.779TyrIle: 1.779 ± 0.653
0.445TyrLys: 0.445 ± 0.436
2.224TyrLeu: 2.224 ± 0.991
0.0TyrMet: 0.0 ± 0.0
0.0TyrAsn: 0.0 ± 0.0
1.779TyrPro: 1.779 ± 0.658
2.669TyrGln: 2.669 ± 1.187
3.114TyrArg: 3.114 ± 0.604
3.114TyrSer: 3.114 ± 0.971
1.779TyrThr: 1.779 ± 0.755
0.89TyrVal: 0.89 ± 0.415
1.335TyrTrp: 1.335 ± 1.187
3.114TyrTyr: 3.114 ± 1.613
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2249 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski