Amino acid dipepetide frequency for Serinus canaria papillomavirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.208AlaAla: 8.208 ± 3.25
2.736AlaCys: 2.736 ± 1.352
2.052AlaAsp: 2.052 ± 0.695
3.42AlaGlu: 3.42 ± 1.057
2.052AlaPhe: 2.052 ± 0.881
5.814AlaGly: 5.814 ± 1.886
0.342AlaHis: 0.342 ± 0.298
2.052AlaIle: 2.052 ± 0.752
3.078AlaLys: 3.078 ± 0.955
3.078AlaLeu: 3.078 ± 1.196
2.394AlaMet: 2.394 ± 0.927
0.684AlaAsn: 0.684 ± 0.371
6.156AlaPro: 6.156 ± 0.771
3.078AlaGln: 3.078 ± 1.061
3.762AlaArg: 3.762 ± 1.195
3.762AlaSer: 3.762 ± 1.368
3.42AlaThr: 3.42 ± 0.879
3.42AlaVal: 3.42 ± 1.057
0.0AlaTrp: 0.0 ± 0.0
2.052AlaTyr: 2.052 ± 0.777
0.0AlaXaa: 0.0 ± 0.0
Cys
1.368CysAla: 1.368 ± 1.002
0.0CysCys: 0.0 ± 0.0
0.342CysAsp: 0.342 ± 0.272
0.342CysGlu: 0.342 ± 0.373
1.71CysPhe: 1.71 ± 0.853
1.026CysGly: 1.026 ± 0.56
0.684CysHis: 0.684 ± 0.459
0.342CysIle: 0.342 ± 0.373
1.026CysLys: 1.026 ± 0.815
2.052CysLeu: 2.052 ± 1.054
0.342CysMet: 0.342 ± 0.373
0.0CysAsn: 0.0 ± 0.0
2.394CysPro: 2.394 ± 0.685
0.0CysGln: 0.0 ± 0.0
3.42CysArg: 3.42 ± 1.486
2.394CysSer: 2.394 ± 1.017
1.026CysThr: 1.026 ± 0.848
0.342CysVal: 0.342 ± 0.298
0.684CysTrp: 0.684 ± 0.381
1.71CysTyr: 1.71 ± 1.334
0.0CysXaa: 0.0 ± 0.0
Asp
3.078AspAla: 3.078 ± 0.605
1.71AspCys: 1.71 ± 0.755
4.104AspAsp: 4.104 ± 1.096
4.788AspGlu: 4.788 ± 1.615
2.394AspPhe: 2.394 ± 0.336
4.788AspGly: 4.788 ± 1.184
0.684AspHis: 0.684 ± 0.347
3.078AspIle: 3.078 ± 1.277
1.368AspLys: 1.368 ± 0.445
5.472AspLeu: 5.472 ± 0.829
0.342AspMet: 0.342 ± 0.319
2.394AspAsn: 2.394 ± 0.818
6.156AspPro: 6.156 ± 1.079
0.684AspGln: 0.684 ± 0.441
4.788AspArg: 4.788 ± 1.357
5.13AspSer: 5.13 ± 0.884
4.104AspThr: 4.104 ± 1.116
3.078AspVal: 3.078 ± 0.935
1.026AspTrp: 1.026 ± 0.427
1.026AspTyr: 1.026 ± 0.386
0.0AspXaa: 0.0 ± 0.0
Glu
3.762GluAla: 3.762 ± 1.051
0.684GluCys: 0.684 ± 0.459
6.498GluAsp: 6.498 ± 1.842
4.104GluGlu: 4.104 ± 0.715
1.368GluPhe: 1.368 ± 0.81
5.472GluGly: 5.472 ± 1.086
1.368GluHis: 1.368 ± 0.656
2.394GluIle: 2.394 ± 0.808
2.052GluLys: 2.052 ± 1.039
4.446GluLeu: 4.446 ± 1.009
0.684GluMet: 0.684 ± 0.478
2.394GluAsn: 2.394 ± 0.637
2.394GluPro: 2.394 ± 0.955
2.394GluGln: 2.394 ± 0.901
2.052GluArg: 2.052 ± 0.654
3.762GluSer: 3.762 ± 0.684
1.368GluThr: 1.368 ± 0.629
6.498GluVal: 6.498 ± 2.14
0.684GluTrp: 0.684 ± 0.544
2.736GluTyr: 2.736 ± 0.727
0.0GluXaa: 0.0 ± 0.0
Phe
1.368PheAla: 1.368 ± 0.58
0.0PheCys: 0.0 ± 0.0
1.71PheAsp: 1.71 ± 0.5
3.42PheGlu: 3.42 ± 0.894
2.736PhePhe: 2.736 ± 0.802
2.052PheGly: 2.052 ± 0.526
1.026PheHis: 1.026 ± 0.503
1.71PheIle: 1.71 ± 0.733
2.052PheLys: 2.052 ± 0.992
3.762PheLeu: 3.762 ± 1.65
0.0PheMet: 0.0 ± 0.0
2.052PheAsn: 2.052 ± 0.66
2.052PhePro: 2.052 ± 1.106
2.394PheGln: 2.394 ± 0.688
3.078PheArg: 3.078 ± 0.673
1.026PheSer: 1.026 ± 0.611
1.368PheThr: 1.368 ± 0.422
0.684PheVal: 0.684 ± 0.458
1.026PheTrp: 1.026 ± 0.35
1.368PheTyr: 1.368 ± 0.491
0.0PheXaa: 0.0 ± 0.0
Gly
2.394GlyAla: 2.394 ± 0.92
0.342GlyCys: 0.342 ± 0.319
3.078GlyAsp: 3.078 ± 1.672
5.472GlyGlu: 5.472 ± 1.036
3.078GlyPhe: 3.078 ± 0.967
5.814GlyGly: 5.814 ± 1.686
1.71GlyHis: 1.71 ± 0.414
4.104GlyIle: 4.104 ± 1.188
3.42GlyLys: 3.42 ± 0.987
8.55GlyLeu: 8.55 ± 2.046
1.368GlyMet: 1.368 ± 0.569
1.71GlyAsn: 1.71 ± 0.639
6.156GlyPro: 6.156 ± 1.936
4.104GlyGln: 4.104 ± 1.94
6.156GlyArg: 6.156 ± 1.171
5.814GlySer: 5.814 ± 1.722
4.104GlyThr: 4.104 ± 1.433
5.814GlyVal: 5.814 ± 1.198
0.342GlyTrp: 0.342 ± 0.272
2.052GlyTyr: 2.052 ± 0.861
0.0GlyXaa: 0.0 ± 0.0
His
1.368HisAla: 1.368 ± 0.798
1.026HisCys: 1.026 ± 0.508
1.368HisAsp: 1.368 ± 0.879
0.684HisGlu: 0.684 ± 0.466
0.684HisPhe: 0.684 ± 0.354
2.052HisGly: 2.052 ± 0.531
1.368HisHis: 1.368 ± 0.6
1.368HisIle: 1.368 ± 0.574
0.0HisLys: 0.0 ± 0.0
1.71HisLeu: 1.71 ± 0.707
0.0HisMet: 0.0 ± 0.0
0.342HisAsn: 0.342 ± 0.272
0.342HisPro: 0.342 ± 0.37
0.0HisGln: 0.0 ± 0.0
1.71HisArg: 1.71 ± 0.896
1.026HisSer: 1.026 ± 0.662
1.71HisThr: 1.71 ± 0.58
2.736HisVal: 2.736 ± 1.182
1.026HisTrp: 1.026 ± 0.508
1.026HisTyr: 1.026 ± 0.554
0.0HisXaa: 0.0 ± 0.0
Ile
1.368IleAla: 1.368 ± 0.81
0.684IleCys: 0.684 ± 0.389
3.078IleAsp: 3.078 ± 1.28
1.368IleGlu: 1.368 ± 0.633
2.052IlePhe: 2.052 ± 0.444
3.078IleGly: 3.078 ± 1.316
1.026IleHis: 1.026 ± 0.42
1.368IleIle: 1.368 ± 0.574
1.026IleLys: 1.026 ± 0.57
5.13IleLeu: 5.13 ± 0.838
0.342IleMet: 0.342 ± 0.319
1.026IleAsn: 1.026 ± 0.35
3.42IlePro: 3.42 ± 1.351
3.762IleGln: 3.762 ± 0.836
2.394IleArg: 2.394 ± 0.956
2.394IleSer: 2.394 ± 0.601
2.394IleThr: 2.394 ± 0.795
1.368IleVal: 1.368 ± 0.762
0.342IleTrp: 0.342 ± 0.302
1.368IleTyr: 1.368 ± 0.798
0.0IleXaa: 0.0 ± 0.0
Lys
2.052LysAla: 2.052 ± 1.0
1.026LysCys: 1.026 ± 0.648
3.762LysAsp: 3.762 ± 1.628
1.026LysGlu: 1.026 ± 0.815
1.368LysPhe: 1.368 ± 0.821
4.446LysGly: 4.446 ± 1.346
1.368LysHis: 1.368 ± 0.578
1.71LysIle: 1.71 ± 0.624
3.078LysLys: 3.078 ± 1.021
2.052LysLeu: 2.052 ± 1.046
1.026LysMet: 1.026 ± 0.621
1.026LysAsn: 1.026 ± 0.815
1.026LysPro: 1.026 ± 0.488
0.684LysGln: 0.684 ± 0.639
3.078LysArg: 3.078 ± 0.945
2.736LysSer: 2.736 ± 1.187
2.394LysThr: 2.394 ± 1.227
0.684LysVal: 0.684 ± 0.503
0.0LysTrp: 0.0 ± 0.0
2.052LysTyr: 2.052 ± 0.58
0.0LysXaa: 0.0 ± 0.0
Leu
2.052LeuAla: 2.052 ± 0.684
3.762LeuCys: 3.762 ± 1.03
5.13LeuAsp: 5.13 ± 0.74
3.762LeuGlu: 3.762 ± 1.568
3.762LeuPhe: 3.762 ± 1.216
6.156LeuGly: 6.156 ± 0.691
1.368LeuHis: 1.368 ± 0.578
2.736LeuIle: 2.736 ± 0.9
5.472LeuLys: 5.472 ± 1.295
6.156LeuLeu: 6.156 ± 1.847
2.052LeuMet: 2.052 ± 0.574
2.052LeuAsn: 2.052 ± 1.365
7.182LeuPro: 7.182 ± 1.155
7.866LeuGln: 7.866 ± 2.237
4.104LeuArg: 4.104 ± 1.794
7.524LeuSer: 7.524 ± 1.487
4.446LeuThr: 4.446 ± 1.327
4.446LeuVal: 4.446 ± 1.291
1.368LeuTrp: 1.368 ± 0.317
1.71LeuTyr: 1.71 ± 0.58
0.0LeuXaa: 0.0 ± 0.0
Met
1.368MetAla: 1.368 ± 0.455
0.0MetCys: 0.0 ± 0.0
0.684MetAsp: 0.684 ± 0.381
1.026MetGlu: 1.026 ± 0.603
0.684MetPhe: 0.684 ± 0.459
0.0MetGly: 0.0 ± 0.0
1.026MetHis: 1.026 ± 0.626
0.684MetIle: 0.684 ± 0.381
0.0MetLys: 0.0 ± 0.0
0.342MetLeu: 0.342 ± 0.272
0.342MetMet: 0.342 ± 0.319
0.684MetAsn: 0.684 ± 0.517
2.052MetPro: 2.052 ± 1.059
1.026MetGln: 1.026 ± 0.603
0.342MetArg: 0.342 ± 0.452
2.052MetSer: 2.052 ± 0.49
0.684MetThr: 0.684 ± 0.517
0.342MetVal: 0.342 ± 0.272
0.684MetTrp: 0.684 ± 0.466
0.342MetTyr: 0.342 ± 0.37
0.0MetXaa: 0.0 ± 0.0
Asn
2.052AsnAla: 2.052 ± 0.791
1.026AsnCys: 1.026 ± 0.45
1.026AsnAsp: 1.026 ± 0.357
1.368AsnGlu: 1.368 ± 0.81
0.342AsnPhe: 0.342 ± 0.452
1.71AsnGly: 1.71 ± 1.179
0.342AsnHis: 0.342 ± 0.272
1.026AsnIle: 1.026 ± 0.386
1.71AsnLys: 1.71 ± 0.77
2.052AsnLeu: 2.052 ± 0.659
0.0AsnMet: 0.0 ± 0.0
2.394AsnAsn: 2.394 ± 0.957
4.104AsnPro: 4.104 ± 1.183
2.052AsnGln: 2.052 ± 1.06
2.052AsnArg: 2.052 ± 1.142
3.078AsnSer: 3.078 ± 1.056
1.368AsnThr: 1.368 ± 0.743
1.368AsnVal: 1.368 ± 0.554
1.368AsnTrp: 1.368 ± 1.076
1.368AsnTyr: 1.368 ± 0.762
0.0AsnXaa: 0.0 ± 0.0
Pro
8.55ProAla: 8.55 ± 2.309
1.026ProCys: 1.026 ± 0.708
5.472ProAsp: 5.472 ± 1.174
5.13ProGlu: 5.13 ± 1.159
2.394ProPhe: 2.394 ± 1.178
5.472ProGly: 5.472 ± 2.728
0.342ProHis: 0.342 ± 0.319
3.42ProIle: 3.42 ± 0.99
2.394ProLys: 2.394 ± 0.812
6.498ProLeu: 6.498 ± 0.662
1.368ProMet: 1.368 ± 0.583
2.394ProAsn: 2.394 ± 1.149
17.784ProPro: 17.784 ± 10.487
1.026ProGln: 1.026 ± 0.723
6.84ProArg: 6.84 ± 1.249
7.524ProSer: 7.524 ± 2.348
3.762ProThr: 3.762 ± 1.112
5.472ProVal: 5.472 ± 1.448
0.684ProTrp: 0.684 ± 0.596
5.472ProTyr: 5.472 ± 2.832
0.0ProXaa: 0.0 ± 0.0
Gln
4.104GlnAla: 4.104 ± 1.182
0.342GlnCys: 0.342 ± 0.272
2.736GlnAsp: 2.736 ± 0.969
2.394GlnGlu: 2.394 ± 0.72
1.026GlnPhe: 1.026 ± 0.565
2.052GlnGly: 2.052 ± 0.604
1.026GlnHis: 1.026 ± 0.599
1.026GlnIle: 1.026 ± 0.386
1.368GlnLys: 1.368 ± 0.6
7.524GlnLeu: 7.524 ± 1.274
0.684GlnMet: 0.684 ± 0.381
2.736GlnAsn: 2.736 ± 1.229
5.472GlnPro: 5.472 ± 2.251
2.394GlnGln: 2.394 ± 0.844
3.42GlnArg: 3.42 ± 0.752
4.788GlnSer: 4.788 ± 1.242
1.71GlnThr: 1.71 ± 0.644
2.052GlnVal: 2.052 ± 0.864
1.026GlnTrp: 1.026 ± 0.386
0.342GlnTyr: 0.342 ± 0.319
0.0GlnXaa: 0.0 ± 0.0
Arg
6.84ArgAla: 6.84 ± 1.652
2.052ArgCys: 2.052 ± 0.872
3.762ArgAsp: 3.762 ± 0.913
4.788ArgGlu: 4.788 ± 1.129
1.71ArgPhe: 1.71 ± 0.553
3.762ArgGly: 3.762 ± 1.3
1.71ArgHis: 1.71 ± 0.612
3.42ArgIle: 3.42 ± 0.812
2.052ArgLys: 2.052 ± 0.917
4.788ArgLeu: 4.788 ± 1.404
0.342ArgMet: 0.342 ± 0.375
2.394ArgAsn: 2.394 ± 0.498
7.866ArgPro: 7.866 ± 2.655
4.788ArgGln: 4.788 ± 1.896
6.498ArgArg: 6.498 ± 2.086
4.446ArgSer: 4.446 ± 0.843
1.368ArgThr: 1.368 ± 0.569
5.814ArgVal: 5.814 ± 1.794
0.684ArgTrp: 0.684 ± 0.371
2.736ArgTyr: 2.736 ± 0.648
0.0ArgXaa: 0.0 ± 0.0
Ser
4.446SerAla: 4.446 ± 1.07
0.684SerCys: 0.684 ± 0.639
5.13SerAsp: 5.13 ± 0.77
4.788SerGlu: 4.788 ± 1.226
2.736SerPhe: 2.736 ± 0.661
8.208SerGly: 8.208 ± 1.644
1.368SerHis: 1.368 ± 0.553
2.052SerIle: 2.052 ± 0.519
2.052SerLys: 2.052 ± 0.721
6.498SerLeu: 6.498 ± 1.365
1.368SerMet: 1.368 ± 0.641
2.052SerAsn: 2.052 ± 1.332
4.788SerPro: 4.788 ± 1.832
2.394SerGln: 2.394 ± 0.946
5.13SerArg: 5.13 ± 1.227
8.892SerSer: 8.892 ± 1.189
6.84SerThr: 6.84 ± 1.54
5.814SerVal: 5.814 ± 1.573
1.026SerTrp: 1.026 ± 0.56
4.446SerTyr: 4.446 ± 2.277
0.0SerXaa: 0.0 ± 0.0
Thr
4.446ThrAla: 4.446 ± 1.018
0.342ThrCys: 0.342 ± 0.373
2.394ThrAsp: 2.394 ± 1.44
2.394ThrGlu: 2.394 ± 0.913
1.71ThrPhe: 1.71 ± 0.707
4.446ThrGly: 4.446 ± 1.73
0.342ThrHis: 0.342 ± 0.319
2.394ThrIle: 2.394 ± 0.675
1.368ThrLys: 1.368 ± 0.984
2.736ThrLeu: 2.736 ± 0.845
0.342ThrMet: 0.342 ± 0.246
2.052ThrAsn: 2.052 ± 0.563
4.788ThrPro: 4.788 ± 1.011
3.42ThrGln: 3.42 ± 1.107
4.104ThrArg: 4.104 ± 1.651
5.13ThrSer: 5.13 ± 1.332
1.368ThrThr: 1.368 ± 0.564
5.814ThrVal: 5.814 ± 1.542
1.368ThrTrp: 1.368 ± 0.66
1.368ThrTyr: 1.368 ± 0.578
0.0ThrXaa: 0.0 ± 0.0
Val
1.368ValAla: 1.368 ± 0.743
2.736ValCys: 2.736 ± 2.151
3.762ValAsp: 3.762 ± 1.281
2.736ValGlu: 2.736 ± 1.185
2.736ValPhe: 2.736 ± 0.93
5.814ValGly: 5.814 ± 1.897
2.052ValHis: 2.052 ± 0.829
2.052ValIle: 2.052 ± 0.637
1.71ValLys: 1.71 ± 0.833
5.814ValLeu: 5.814 ± 1.802
0.342ValMet: 0.342 ± 0.298
1.71ValAsn: 1.71 ± 1.229
6.84ValPro: 6.84 ± 1.618
3.078ValGln: 3.078 ± 0.9
4.446ValArg: 4.446 ± 1.753
5.13ValSer: 5.13 ± 0.866
5.814ValThr: 5.814 ± 2.046
3.42ValVal: 3.42 ± 0.886
0.342ValTrp: 0.342 ± 0.319
1.71ValTyr: 1.71 ± 0.716
0.0ValXaa: 0.0 ± 0.0
Trp
0.684TrpAla: 0.684 ± 0.389
0.342TrpCys: 0.342 ± 0.272
1.026TrpAsp: 1.026 ± 0.603
1.368TrpGlu: 1.368 ± 0.58
0.0TrpPhe: 0.0 ± 0.0
0.684TrpGly: 0.684 ± 0.639
1.026TrpHis: 1.026 ± 0.655
1.368TrpIle: 1.368 ± 0.673
0.342TrpLys: 0.342 ± 0.272
2.052TrpLeu: 2.052 ± 0.88
0.342TrpMet: 0.342 ± 0.302
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.026TrpGln: 1.026 ± 0.73
1.368TrpArg: 1.368 ± 0.881
1.026TrpSer: 1.026 ± 0.482
1.71TrpThr: 1.71 ± 0.66
1.026TrpVal: 1.026 ± 0.433
0.342TrpTrp: 0.342 ± 0.298
0.342TrpTyr: 0.342 ± 0.302
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.684TyrAla: 0.684 ± 0.381
0.684TyrCys: 0.684 ± 0.622
3.078TyrAsp: 3.078 ± 1.19
2.736TyrGlu: 2.736 ± 0.95
0.342TyrPhe: 0.342 ± 0.319
2.736TyrGly: 2.736 ± 1.085
1.368TyrHis: 1.368 ± 0.666
0.684TyrIle: 0.684 ± 0.389
1.026TyrLys: 1.026 ± 0.917
2.394TyrLeu: 2.394 ± 0.917
0.342TyrMet: 0.342 ± 0.452
1.71TyrAsn: 1.71 ± 0.496
2.052TyrPro: 2.052 ± 1.099
2.052TyrGln: 2.052 ± 1.456
3.42TyrArg: 3.42 ± 1.654
3.078TyrSer: 3.078 ± 0.774
1.368TyrThr: 1.368 ± 0.424
3.42TyrVal: 3.42 ± 0.953
2.052TyrTrp: 2.052 ± 0.866
2.052TyrTyr: 2.052 ± 1.029
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (2925 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski