Amino acid dipepetide frequency for Chrysochromulina parva virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.916AlaAla: 1.916 ± 0.941
0.709AlaCys: 0.709 ± 0.161
1.135AlaAsp: 1.135 ± 0.342
1.916AlaGlu: 1.916 ± 0.376
0.78AlaPhe: 0.78 ± 0.267
1.348AlaGly: 1.348 ± 0.356
0.709AlaHis: 0.709 ± 0.286
3.618AlaIle: 3.618 ± 0.572
4.044AlaLys: 4.044 ± 0.578
3.618AlaLeu: 3.618 ± 0.659
0.639AlaMet: 0.639 ± 0.191
3.122AlaAsn: 3.122 ± 0.699
0.993AlaPro: 0.993 ± 0.236
1.206AlaGln: 1.206 ± 0.389
0.993AlaArg: 0.993 ± 0.285
2.128AlaSer: 2.128 ± 0.428
2.909AlaThr: 2.909 ± 0.97
1.916AlaVal: 1.916 ± 0.518
0.355AlaTrp: 0.355 ± 0.177
0.78AlaTyr: 0.78 ± 0.229
0.0AlaXaa: 0.0 ± 0.0
Cys
0.568CysAla: 0.568 ± 0.181
0.639CysCys: 0.639 ± 0.25
0.993CysAsp: 0.993 ± 0.265
0.922CysGlu: 0.922 ± 0.265
0.497CysPhe: 0.497 ± 0.227
1.064CysGly: 1.064 ± 0.404
0.213CysHis: 0.213 ± 0.108
1.348CysIle: 1.348 ± 0.399
2.128CysLys: 2.128 ± 0.325
1.206CysLeu: 1.206 ± 0.282
0.213CysMet: 0.213 ± 0.121
1.419CysAsn: 1.419 ± 0.366
0.922CysPro: 0.922 ± 0.29
0.284CysGln: 0.284 ± 0.111
0.355CysArg: 0.355 ± 0.172
1.845CysSer: 1.845 ± 0.449
0.497CysThr: 0.497 ± 0.156
0.851CysVal: 0.851 ± 0.25
0.0CysTrp: 0.0 ± 0.0
0.78CysTyr: 0.78 ± 0.25
0.0CysXaa: 0.0 ± 0.0
Asp
2.838AspAla: 2.838 ± 0.509
0.639AspCys: 0.639 ± 0.2
5.25AspAsp: 5.25 ± 1.513
6.172AspGlu: 6.172 ± 1.783
3.193AspPhe: 3.193 ± 0.506
1.561AspGly: 1.561 ± 0.294
0.213AspHis: 0.213 ± 0.104
4.47AspIle: 4.47 ± 0.567
4.895AspLys: 4.895 ± 0.775
5.321AspLeu: 5.321 ± 0.827
0.568AspMet: 0.568 ± 0.21
3.689AspAsn: 3.689 ± 0.499
1.135AspPro: 1.135 ± 0.314
0.78AspGln: 0.78 ± 0.26
0.568AspArg: 0.568 ± 0.169
3.76AspSer: 3.76 ± 0.47
2.057AspThr: 2.057 ± 0.448
1.916AspVal: 1.916 ± 0.439
0.355AspTrp: 0.355 ± 0.167
3.76AspTyr: 3.76 ± 0.521
0.0AspXaa: 0.0 ± 0.0
Glu
2.27GluAla: 2.27 ± 0.52
1.277GluCys: 1.277 ± 0.349
6.456GluAsp: 6.456 ± 2.138
7.591GluGlu: 7.591 ± 1.531
2.696GluPhe: 2.696 ± 0.464
1.632GluGly: 1.632 ± 0.437
0.922GluHis: 0.922 ± 0.238
4.399GluIle: 4.399 ± 0.552
7.449GluLys: 7.449 ± 1.336
7.237GluLeu: 7.237 ± 0.9
0.426GluMet: 0.426 ± 0.158
6.527GluAsn: 6.527 ± 1.079
1.632GluPro: 1.632 ± 0.322
2.909GluGln: 2.909 ± 0.675
2.27GluArg: 2.27 ± 0.476
3.335GluSer: 3.335 ± 0.553
4.044GluThr: 4.044 ± 0.714
2.625GluVal: 2.625 ± 0.56
0.639GluTrp: 0.639 ± 0.196
2.483GluTyr: 2.483 ± 0.317
0.0GluXaa: 0.0 ± 0.0
Phe
1.277PheAla: 1.277 ± 0.353
0.993PheCys: 0.993 ± 0.203
2.27PheAsp: 2.27 ± 0.421
2.483PheGlu: 2.483 ± 0.497
1.561PhePhe: 1.561 ± 0.361
1.277PheGly: 1.277 ± 0.344
0.78PheHis: 0.78 ± 0.282
5.25PheIle: 5.25 ± 0.746
4.753PheLys: 4.753 ± 0.736
5.037PheLeu: 5.037 ± 0.802
0.851PheMet: 0.851 ± 0.281
4.47PheAsn: 4.47 ± 0.546
1.135PhePro: 1.135 ± 0.276
0.709PheGln: 0.709 ± 0.178
1.49PheArg: 1.49 ± 0.299
4.824PheSer: 4.824 ± 0.991
2.98PheThr: 2.98 ± 0.489
2.27PheVal: 2.27 ± 0.5
0.142PheTrp: 0.142 ± 0.109
2.199PheTyr: 2.199 ± 0.359
0.0PheXaa: 0.0 ± 0.0
Gly
1.277GlyAla: 1.277 ± 0.377
0.497GlyCys: 0.497 ± 0.173
1.774GlyAsp: 1.774 ± 0.306
1.703GlyGlu: 1.703 ± 0.454
1.774GlyPhe: 1.774 ± 0.318
1.774GlyGly: 1.774 ± 0.546
0.284GlyHis: 0.284 ± 0.12
2.767GlyIle: 2.767 ± 0.47
4.044GlyLys: 4.044 ± 0.612
3.193GlyLeu: 3.193 ± 0.416
0.78GlyMet: 0.78 ± 0.275
1.561GlyAsn: 1.561 ± 0.334
0.639GlyPro: 0.639 ± 0.183
0.851GlyGln: 0.851 ± 0.219
1.135GlyArg: 1.135 ± 0.378
4.044GlySer: 4.044 ± 1.768
3.405GlyThr: 3.405 ± 1.519
1.703GlyVal: 1.703 ± 0.343
0.284GlyTrp: 0.284 ± 0.136
1.49GlyTyr: 1.49 ± 0.384
0.0GlyXaa: 0.0 ± 0.0
His
0.639HisAla: 0.639 ± 0.284
0.284HisCys: 0.284 ± 0.183
0.497HisAsp: 0.497 ± 0.18
1.348HisGlu: 1.348 ± 0.378
0.709HisPhe: 0.709 ± 0.211
0.497HisGly: 0.497 ± 0.147
0.284HisHis: 0.284 ± 0.213
1.916HisIle: 1.916 ± 0.324
1.703HisLys: 1.703 ± 0.358
2.909HisLeu: 2.909 ± 1.881
0.355HisMet: 0.355 ± 0.17
1.774HisAsn: 1.774 ± 0.4
0.355HisPro: 0.355 ± 0.19
0.709HisGln: 0.709 ± 0.468
0.78HisArg: 0.78 ± 0.275
0.851HisSer: 0.851 ± 0.265
0.922HisThr: 0.922 ± 0.302
0.355HisVal: 0.355 ± 0.126
0.0HisTrp: 0.0 ± 0.0
0.78HisTyr: 0.78 ± 0.254
0.0HisXaa: 0.0 ± 0.0
Ile
3.689IleAla: 3.689 ± 0.544
1.348IleCys: 1.348 ± 0.348
5.25IleAsp: 5.25 ± 0.668
5.818IleGlu: 5.818 ± 0.843
6.101IlePhe: 6.101 ± 0.818
2.554IleGly: 2.554 ± 0.279
1.064IleHis: 1.064 ± 0.238
10.358IleIle: 10.358 ± 1.219
10.358IleLys: 10.358 ± 0.868
7.875IleLeu: 7.875 ± 0.672
1.632IleMet: 1.632 ± 0.348
11.635IleAsn: 11.635 ± 1.385
2.909IlePro: 2.909 ± 0.455
2.767IleGln: 2.767 ± 0.521
1.987IleArg: 1.987 ± 0.443
5.534IleSer: 5.534 ± 0.585
5.818IleThr: 5.818 ± 0.594
4.47IleVal: 4.47 ± 0.61
0.355IleTrp: 0.355 ± 0.149
3.476IleTyr: 3.476 ± 0.516
0.0IleXaa: 0.0 ± 0.0
Lys
3.122LysAla: 3.122 ± 0.495
1.348LysCys: 1.348 ± 0.336
4.399LysAsp: 4.399 ± 0.815
7.379LysGlu: 7.379 ± 1.161
4.186LysPhe: 4.186 ± 0.57
3.264LysGly: 3.264 ± 0.533
2.767LysHis: 2.767 ± 0.587
10.145LysIle: 10.145 ± 0.883
12.487LysLys: 12.487 ± 1.567
10.004LysLeu: 10.004 ± 0.929
2.128LysMet: 2.128 ± 0.507
11.777LysAsn: 11.777 ± 1.162
1.774LysPro: 1.774 ± 0.34
4.044LysGln: 4.044 ± 0.582
2.625LysArg: 2.625 ± 0.522
6.74LysSer: 6.74 ± 0.801
5.96LysThr: 5.96 ± 0.748
3.476LysVal: 3.476 ± 0.516
0.639LysTrp: 0.639 ± 0.233
7.52LysTyr: 7.52 ± 0.83
0.0LysXaa: 0.0 ± 0.0
Leu
2.27LeuAla: 2.27 ± 0.477
1.561LeuCys: 1.561 ± 0.336
4.47LeuAsp: 4.47 ± 0.71
7.024LeuGlu: 7.024 ± 0.825
6.314LeuPhe: 6.314 ± 0.938
2.696LeuGly: 2.696 ± 0.478
3.405LeuHis: 3.405 ± 1.796
9.72LeuIle: 9.72 ± 0.733
8.514LeuLys: 8.514 ± 0.708
17.737LeuLeu: 17.737 ± 6.762
1.135LeuMet: 1.135 ± 0.221
7.733LeuAsn: 7.733 ± 1.185
2.483LeuPro: 2.483 ± 0.532
2.767LeuGln: 2.767 ± 0.396
2.909LeuArg: 2.909 ± 0.696
6.243LeuSer: 6.243 ± 0.612
4.257LeuThr: 4.257 ± 0.537
5.321LeuVal: 5.321 ± 1.663
0.568LeuTrp: 0.568 ± 0.167
4.753LeuTyr: 4.753 ± 0.645
0.0LeuXaa: 0.0 ± 0.0
Met
0.426MetAla: 0.426 ± 0.186
0.568MetCys: 0.568 ± 0.169
0.851MetAsp: 0.851 ± 0.241
1.561MetGlu: 1.561 ± 0.399
0.709MetPhe: 0.709 ± 0.266
0.709MetGly: 0.709 ± 0.275
0.568MetHis: 0.568 ± 0.175
0.993MetIle: 0.993 ± 0.285
1.845MetLys: 1.845 ± 0.354
1.49MetLeu: 1.49 ± 0.351
0.355MetMet: 0.355 ± 0.153
0.851MetAsn: 0.851 ± 0.186
0.78MetPro: 0.78 ± 0.292
0.355MetGln: 0.355 ± 0.15
0.78MetArg: 0.78 ± 0.265
1.987MetSer: 1.987 ± 0.449
1.277MetThr: 1.277 ± 0.368
0.497MetVal: 0.497 ± 0.203
0.071MetTrp: 0.071 ± 0.074
0.497MetTyr: 0.497 ± 0.206
0.0MetXaa: 0.0 ± 0.0
Asn
3.902AsnAla: 3.902 ± 0.416
1.135AsnCys: 1.135 ± 0.291
4.895AsnAsp: 4.895 ± 0.574
5.96AsnGlu: 5.96 ± 0.668
4.328AsnPhe: 4.328 ± 0.566
2.767AsnGly: 2.767 ± 0.445
1.206AsnHis: 1.206 ± 0.282
12.416AsnIle: 12.416 ± 1.109
10.642AsnLys: 10.642 ± 1.243
6.953AsnLeu: 6.953 ± 0.801
2.412AsnMet: 2.412 ± 0.442
13.551AsnAsn: 13.551 ± 2.023
1.845AsnPro: 1.845 ± 0.467
1.703AsnGln: 1.703 ± 0.371
1.135AsnArg: 1.135 ± 0.325
7.379AsnSer: 7.379 ± 0.798
4.753AsnThr: 4.753 ± 0.528
4.328AsnVal: 4.328 ± 0.6
0.284AsnTrp: 0.284 ± 0.146
6.172AsnTyr: 6.172 ± 0.863
0.0AsnXaa: 0.0 ± 0.0
Pro
0.993ProAla: 0.993 ± 0.297
0.497ProCys: 0.497 ± 0.237
1.419ProAsp: 1.419 ± 0.376
1.774ProGlu: 1.774 ± 0.339
1.064ProPhe: 1.064 ± 0.218
0.78ProGly: 0.78 ± 0.293
0.78ProHis: 0.78 ± 0.217
2.696ProIle: 2.696 ± 0.503
2.199ProLys: 2.199 ± 0.271
2.483ProLeu: 2.483 ± 0.416
0.851ProMet: 0.851 ± 0.232
2.27ProAsn: 2.27 ± 0.401
2.341ProPro: 2.341 ± 1.45
0.426ProGln: 0.426 ± 0.204
0.851ProArg: 0.851 ± 0.302
2.341ProSer: 2.341 ± 0.587
0.709ProThr: 0.709 ± 0.272
0.993ProVal: 0.993 ± 0.261
0.071ProTrp: 0.071 ± 0.07
2.199ProTyr: 2.199 ± 0.415
0.0ProXaa: 0.0 ± 0.0
Gln
1.206GlnAla: 1.206 ± 0.353
0.497GlnCys: 0.497 ± 0.232
1.561GlnAsp: 1.561 ± 0.489
2.625GlnGlu: 2.625 ± 0.553
1.277GlnPhe: 1.277 ± 0.336
0.497GlnGly: 0.497 ± 0.15
0.284GlnHis: 0.284 ± 0.135
2.341GlnIle: 2.341 ± 0.428
3.76GlnLys: 3.76 ± 0.382
2.483GlnLeu: 2.483 ± 0.434
0.639GlnMet: 0.639 ± 0.215
2.767GlnAsn: 2.767 ± 0.467
0.78GlnPro: 0.78 ± 0.165
1.49GlnGln: 1.49 ± 0.52
0.922GlnArg: 0.922 ± 0.319
1.987GlnSer: 1.987 ± 0.305
1.206GlnThr: 1.206 ± 0.335
0.922GlnVal: 0.922 ± 0.564
0.142GlnTrp: 0.142 ± 0.109
0.922GlnTyr: 0.922 ± 0.258
0.0GlnXaa: 0.0 ± 0.0
Arg
1.632ArgAla: 1.632 ± 0.399
0.709ArgCys: 0.709 ± 0.241
1.348ArgAsp: 1.348 ± 0.294
2.199ArgGlu: 2.199 ± 0.428
1.135ArgPhe: 1.135 ± 0.321
1.064ArgGly: 1.064 ± 0.326
0.639ArgHis: 0.639 ± 0.249
1.703ArgIle: 1.703 ± 0.324
3.76ArgLys: 3.76 ± 0.696
2.483ArgLeu: 2.483 ± 0.567
0.071ArgMet: 0.071 ± 0.065
2.199ArgAsn: 2.199 ± 0.379
0.78ArgPro: 0.78 ± 0.282
1.703ArgGln: 1.703 ± 0.565
2.625ArgArg: 2.625 ± 0.839
1.135ArgSer: 1.135 ± 0.41
1.561ArgThr: 1.561 ± 0.424
0.639ArgVal: 0.639 ± 0.217
0.213ArgTrp: 0.213 ± 0.133
1.277ArgTyr: 1.277 ± 0.34
0.0ArgXaa: 0.0 ± 0.0
Ser
3.122SerAla: 3.122 ± 1.01
1.845SerCys: 1.845 ± 0.616
3.831SerAsp: 3.831 ± 0.711
3.689SerGlu: 3.689 ± 0.782
3.051SerPhe: 3.051 ± 0.479
4.541SerGly: 4.541 ± 1.912
0.639SerHis: 0.639 ± 0.191
5.96SerIle: 5.96 ± 0.614
7.449SerLys: 7.449 ± 0.864
7.095SerLeu: 7.095 ± 0.826
1.135SerMet: 1.135 ± 0.26
7.804SerAsn: 7.804 ± 0.735
1.916SerPro: 1.916 ± 0.623
1.206SerGln: 1.206 ± 0.377
2.554SerArg: 2.554 ± 0.51
9.862SerSer: 9.862 ± 4.057
2.767SerThr: 2.767 ± 0.504
2.483SerVal: 2.483 ± 0.419
0.426SerTrp: 0.426 ± 0.211
3.76SerTyr: 3.76 ± 0.738
0.0SerXaa: 0.0 ± 0.0
Thr
0.993ThrAla: 0.993 ± 0.419
0.851ThrCys: 0.851 ± 0.243
2.199ThrAsp: 2.199 ± 0.344
2.483ThrGlu: 2.483 ± 0.72
2.128ThrPhe: 2.128 ± 0.521
2.483ThrGly: 2.483 ± 1.361
1.49ThrHis: 1.49 ± 0.473
5.25ThrIle: 5.25 ± 0.975
5.108ThrLys: 5.108 ± 0.923
5.037ThrLeu: 5.037 ± 0.543
1.064ThrMet: 1.064 ± 0.271
6.031ThrAsn: 6.031 ± 0.901
1.561ThrPro: 1.561 ± 0.244
1.916ThrGln: 1.916 ± 0.437
2.767ThrArg: 2.767 ± 0.691
3.902ThrSer: 3.902 ± 0.953
2.909ThrThr: 2.909 ± 0.954
1.064ThrVal: 1.064 ± 0.317
0.142ThrTrp: 0.142 ± 0.1
2.767ThrTyr: 2.767 ± 0.329
0.0ThrXaa: 0.0 ± 0.0
Val
1.49ValAla: 1.49 ± 0.352
0.639ValCys: 0.639 ± 0.25
1.561ValAsp: 1.561 ± 0.306
2.554ValGlu: 2.554 ± 0.4
2.27ValPhe: 2.27 ± 0.573
1.348ValGly: 1.348 ± 0.269
0.426ValHis: 0.426 ± 0.15
3.547ValIle: 3.547 ± 0.609
3.618ValLys: 3.618 ± 0.62
4.966ValLeu: 4.966 ± 1.44
0.497ValMet: 0.497 ± 0.222
3.335ValAsn: 3.335 ± 0.563
1.987ValPro: 1.987 ± 0.44
1.348ValGln: 1.348 ± 0.27
1.064ValArg: 1.064 ± 0.294
3.831ValSer: 3.831 ± 0.831
1.419ValThr: 1.419 ± 0.263
2.341ValVal: 2.341 ± 0.756
0.284ValTrp: 0.284 ± 0.182
2.199ValTyr: 2.199 ± 0.55
0.0ValXaa: 0.0 ± 0.0
Trp
0.071TrpAla: 0.071 ± 0.069
0.0TrpCys: 0.0 ± 0.0
0.355TrpAsp: 0.355 ± 0.157
0.497TrpGlu: 0.497 ± 0.185
0.284TrpPhe: 0.284 ± 0.145
0.709TrpGly: 0.709 ± 0.35
0.213TrpHis: 0.213 ± 0.121
0.568TrpIle: 0.568 ± 0.217
0.355TrpLys: 0.355 ± 0.179
0.284TrpLeu: 0.284 ± 0.16
0.213TrpMet: 0.213 ± 0.15
0.213TrpAsn: 0.213 ± 0.112
0.142TrpPro: 0.142 ± 0.1
0.284TrpGln: 0.284 ± 0.128
0.071TrpArg: 0.071 ± 0.073
0.284TrpSer: 0.284 ± 0.142
0.213TrpThr: 0.213 ± 0.127
0.284TrpVal: 0.284 ± 0.134
0.142TrpTrp: 0.142 ± 0.09
0.142TrpTyr: 0.142 ± 0.088
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.135TyrAla: 1.135 ± 0.235
0.709TyrCys: 0.709 ± 0.194
2.625TyrAsp: 2.625 ± 0.384
3.122TyrGlu: 3.122 ± 0.464
2.767TyrPhe: 2.767 ± 0.466
2.412TyrGly: 2.412 ± 0.451
0.78TyrHis: 0.78 ± 0.198
5.534TyrIle: 5.534 ± 0.661
6.669TyrLys: 6.669 ± 1.071
4.47TyrLeu: 4.47 ± 0.415
1.135TyrMet: 1.135 ± 0.223
5.037TyrAsn: 5.037 ± 0.775
1.632TyrPro: 1.632 ± 0.323
0.851TyrGln: 0.851 ± 0.201
0.993TyrArg: 0.993 ± 0.239
3.122TyrSer: 3.122 ± 0.423
2.483TyrThr: 2.483 ± 0.426
2.27TyrVal: 2.27 ± 0.388
0.213TyrTrp: 0.213 ± 0.117
3.264TyrTyr: 3.264 ± 0.511
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 45 proteins (14096 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski