Amino acid dipepetide frequency for Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937))

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.166AlaAla: 11.166 ± 0.141	1.151AlaCys: 1.151 ± 0.034	5.381AlaAsp: 5.381 ± 0.063	5.444AlaGlu: 5.444 ± 0.07	3.591AlaPhe: 3.591 ± 0.06	8.08AlaGly: 8.08 ± 0.131	1.915AlaHis: 1.915 ± 0.039	5.592AlaIle: 5.592 ± 0.067	3.171AlaLys: 3.171 ± 0.052	12.458AlaLeu: 12.458 ± 0.113	2.987AlaMet: 2.987 ± 0.041	2.957AlaAsn: 2.957 ± 0.067	3.955AlaPro: 3.955 ± 0.06	4.701AlaGln: 4.701 ± 0.063	6.264AlaArg: 6.264 ± 0.062	5.961AlaSer: 5.961 ± 0.061	4.808AlaThr: 4.808 ± 0.086	7.089AlaVal: 7.089 ± 0.084	1.347AlaTrp: 1.347 ± 0.033	2.276AlaTyr: 2.276 ± 0.047	0.001AlaXaa: 0.001 ± 0.001
Cys	0.998CysAla: 0.998 ± 0.027	0.198CysCys: 0.198 ± 0.013	0.599CysAsp: 0.599 ± 0.022	0.532CysGlu: 0.532 ± 0.02	0.457CysPhe: 0.457 ± 0.019	1.076CysGly: 1.076 ± 0.032	0.366CysHis: 0.366 ± 0.016	0.52CysIle: 0.52 ± 0.021	0.267CysLys: 0.267 ± 0.014	1.114CysLeu: 1.114 ± 0.034	0.234CysMet: 0.234 ± 0.014	0.338CysAsn: 0.338 ± 0.016	0.512CysPro: 0.512 ± 0.02	0.489CysGln: 0.489 ± 0.02	0.816CysArg: 0.816 ± 0.028	0.632CysSer: 0.632 ± 0.021	0.469CysThr: 0.469 ± 0.019	0.733CysVal: 0.733 ± 0.024	0.188CysTrp: 0.188 ± 0.011	0.346CysTyr: 0.346 ± 0.016	0.001CysXaa: 0.001 ± 0.001
Asp	5.493AspAla: 5.493 ± 0.066	0.532AspCys: 0.532 ± 0.02	3.112AspAsp: 3.112 ± 0.056	3.349AspGlu: 3.349 ± 0.051	2.016AspPhe: 2.016 ± 0.038	4.1AspGly: 4.1 ± 0.078	1.062AspHis: 1.062 ± 0.029	3.506AspIle: 3.506 ± 0.053	2.172AspLys: 2.172 ± 0.046	4.595AspLeu: 4.595 ± 0.062	1.281AspMet: 1.281 ± 0.031	2.206AspAsn: 2.206 ± 0.049	2.266AspPro: 2.266 ± 0.042	1.759AspGln: 1.759 ± 0.04	2.976AspArg: 2.976 ± 0.05	3.019AspSer: 3.019 ± 0.058	2.694AspThr: 2.694 ± 0.063	3.82AspVal: 3.82 ± 0.059	0.898AspTrp: 0.898 ± 0.025	1.908AspTyr: 1.908 ± 0.038	0.001AspXaa: 0.001 ± 0.001
Glu	4.765GluAla: 4.765 ± 0.06	0.454GluCys: 0.454 ± 0.022	2.112GluAsp: 2.112 ± 0.047	2.815GluGlu: 2.815 ± 0.056	1.685GluPhe: 1.685 ± 0.038	3.05GluGly: 3.05 ± 0.052	1.393GluHis: 1.393 ± 0.033	2.913GluIle: 2.913 ± 0.046	2.701GluLys: 2.701 ± 0.054	5.72GluLeu: 5.72 ± 0.066	1.481GluMet: 1.481 ± 0.031	2.069GluAsn: 2.069 ± 0.04	2.179GluPro: 2.179 ± 0.046	3.737GluGln: 3.737 ± 0.067	3.935GluArg: 3.935 ± 0.062	2.774GluSer: 2.774 ± 0.041	2.713GluThr: 2.713 ± 0.044	3.396GluVal: 3.396 ± 0.053	0.745GluTrp: 0.745 ± 0.024	1.329GluTyr: 1.329 ± 0.026	0.001GluXaa: 0.001 ± 0.001
Phe	3.519PheAla: 3.519 ± 0.057	0.555PheCys: 0.555 ± 0.022	2.268PheAsp: 2.268 ± 0.042	1.607PheGlu: 1.607 ± 0.034	1.603PhePhe: 1.603 ± 0.044	3.038PheGly: 3.038 ± 0.057	0.857PheHis: 0.857 ± 0.025	2.358PheIle: 2.358 ± 0.045	1.11PheLys: 1.11 ± 0.031	3.334PheLeu: 3.334 ± 0.057	0.963PheMet: 0.963 ± 0.028	1.63PheAsn: 1.63 ± 0.036	1.585PhePro: 1.585 ± 0.038	1.222PheGln: 1.222 ± 0.028	2.121PheArg: 2.121 ± 0.043	3.208PheSer: 3.208 ± 0.049	2.171PheThr: 2.171 ± 0.04	2.366PheVal: 2.366 ± 0.048	0.566PheTrp: 0.566 ± 0.023	1.236PheTyr: 1.236 ± 0.036	0.0PheXaa: 0.0 ± 0.0
Gly	6.337GlyAla: 6.337 ± 0.097	0.998GlyCys: 0.998 ± 0.03	3.796GlyAsp: 3.796 ± 0.064	4.367GlyGlu: 4.367 ± 0.067	3.161GlyPhe: 3.161 ± 0.048	5.451GlyGly: 5.451 ± 0.125	1.639GlyHis: 1.639 ± 0.038	4.57GlyIle: 4.57 ± 0.065	3.582GlyLys: 3.582 ± 0.045	7.683GlyLeu: 7.683 ± 0.087	2.284GlyMet: 2.284 ± 0.041	2.801GlyAsn: 2.801 ± 0.065	2.086GlyPro: 2.086 ± 0.039	3.21GlyGln: 3.21 ± 0.064	4.236GlyArg: 4.236 ± 0.062	4.251GlySer: 4.251 ± 0.071	3.625GlyThr: 3.625 ± 0.098	5.825GlyVal: 5.825 ± 0.061	1.304GlyTrp: 1.304 ± 0.034	2.589GlyTyr: 2.589 ± 0.051	0.001GlyXaa: 0.001 ± 0.001
His	1.999HisAla: 1.999 ± 0.041	0.362HisCys: 0.362 ± 0.018	1.366HisAsp: 1.366 ± 0.033	1.078HisGlu: 1.078 ± 0.028	0.979HisPhe: 0.979 ± 0.031	1.77HisGly: 1.77 ± 0.033	0.88HisHis: 0.88 ± 0.031	1.301HisIle: 1.301 ± 0.029	0.656HisLys: 0.656 ± 0.022	2.339HisLeu: 2.339 ± 0.049	0.492HisMet: 0.492 ± 0.019	0.782HisAsn: 0.782 ± 0.026	1.479HisPro: 1.479 ± 0.034	1.343HisGln: 1.343 ± 0.037	1.481HisArg: 1.481 ± 0.038	1.347HisSer: 1.347 ± 0.034	1.168HisThr: 1.168 ± 0.03	1.265HisVal: 1.265 ± 0.03	0.453HisTrp: 0.453 ± 0.018	0.923HisTyr: 0.923 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	6.164IleAla: 6.164 ± 0.082	0.592IleCys: 0.592 ± 0.019	3.353IleAsp: 3.353 ± 0.057	2.96IleGlu: 2.96 ± 0.059	1.763IlePhe: 1.763 ± 0.042	4.5IleGly: 4.5 ± 0.059	1.151IleHis: 1.151 ± 0.03	2.958IleIle: 2.958 ± 0.068	2.074IleLys: 2.074 ± 0.044	4.619IleLeu: 4.619 ± 0.077	1.219IleMet: 1.219 ± 0.035	2.467IleAsn: 2.467 ± 0.052	2.618IlePro: 2.618 ± 0.047	1.957IleGln: 1.957 ± 0.038	3.391IleArg: 3.391 ± 0.052	3.701IleSer: 3.701 ± 0.062	3.39IleThr: 3.39 ± 0.048	3.595IleVal: 3.595 ± 0.053	0.593IleTrp: 0.593 ± 0.021	1.437IleTyr: 1.437 ± 0.035	0.001IleXaa: 0.001 ± 0.001
Lys	3.587LysAla: 3.587 ± 0.056	0.232LysCys: 0.232 ± 0.013	1.82LysAsp: 1.82 ± 0.036	1.884LysGlu: 1.884 ± 0.046	0.964LysPhe: 0.964 ± 0.028	2.524LysGly: 2.524 ± 0.041	0.751LysHis: 0.751 ± 0.022	1.97LysIle: 1.97 ± 0.044	1.899LysLys: 1.899 ± 0.06	3.671LysLeu: 3.671 ± 0.058	0.976LysMet: 0.976 ± 0.029	1.629LysAsn: 1.629 ± 0.04	2.003LysPro: 2.003 ± 0.038	1.852LysGln: 1.852 ± 0.047	2.278LysArg: 2.278 ± 0.044	2.144LysSer: 2.144 ± 0.044	2.451LysThr: 2.451 ± 0.049	2.493LysVal: 2.493 ± 0.044	0.37LysTrp: 0.37 ± 0.018	0.976LysTyr: 0.976 ± 0.03	0.0LysXaa: 0.0 ± 0.0
Leu	12.104LeuAla: 12.104 ± 0.11	1.331LeuCys: 1.331 ± 0.032	5.682LeuAsp: 5.682 ± 0.075	5.136LeuGlu: 5.136 ± 0.07	4.321LeuPhe: 4.321 ± 0.073	7.443LeuGly: 7.443 ± 0.091	2.4LeuHis: 2.4 ± 0.041	5.742LeuIle: 5.742 ± 0.093	4.143LeuLys: 4.143 ± 0.063	12.716LeuLeu: 12.716 ± 0.164	2.958LeuMet: 2.958 ± 0.048	4.084LeuAsn: 4.084 ± 0.057	6.092LeuPro: 6.092 ± 0.084	4.496LeuGln: 4.496 ± 0.073	6.708LeuArg: 6.708 ± 0.074	8.095LeuSer: 8.095 ± 0.101	6.795LeuThr: 6.795 ± 0.11	7.157LeuVal: 7.157 ± 0.081	1.357LeuTrp: 1.357 ± 0.035	2.669LeuTyr: 2.669 ± 0.044	0.001LeuXaa: 0.001 ± 0.002
Met	2.791MetAla: 2.791 ± 0.043	0.187MetCys: 0.187 ± 0.013	1.134MetAsp: 1.134 ± 0.023	1.161MetGlu: 1.161 ± 0.031	0.796MetPhe: 0.796 ± 0.025	1.733MetGly: 1.733 ± 0.032	0.492MetHis: 0.492 ± 0.02	1.344MetIle: 1.344 ± 0.036	1.193MetLys: 1.193 ± 0.03	3.155MetLeu: 3.155 ± 0.052	0.857MetMet: 0.857 ± 0.027	1.051MetAsn: 1.051 ± 0.029	1.352MetPro: 1.352 ± 0.032	1.2MetGln: 1.2 ± 0.028	1.449MetArg: 1.449 ± 0.031	1.834MetSer: 1.834 ± 0.037	1.779MetThr: 1.779 ± 0.036	1.885MetVal: 1.885 ± 0.038	0.217MetTrp: 0.217 ± 0.012	0.482MetTyr: 0.482 ± 0.021	0.001MetXaa: 0.001 ± 0.001
Asn	3.661AsnAla: 3.661 ± 0.073	0.312AsnCys: 0.312 ± 0.017	1.956AsnAsp: 1.956 ± 0.058	1.686AsnGlu: 1.686 ± 0.04	1.178AsnPhe: 1.178 ± 0.035	2.99AsnGly: 2.99 ± 0.063	0.82AsnHis: 0.82 ± 0.026	2.119AsnIle: 2.119 ± 0.044	1.346AsnLys: 1.346 ± 0.035	3.423AsnLeu: 3.423 ± 0.049	0.84AsnMet: 0.84 ± 0.025	1.512AsnAsn: 1.512 ± 0.038	2.057AsnPro: 2.057 ± 0.048	1.685AsnGln: 1.685 ± 0.038	2.256AsnArg: 2.256 ± 0.043	1.964AsnSer: 1.964 ± 0.04	2.0AsnThr: 2.0 ± 0.039	2.385AsnVal: 2.385 ± 0.047	0.531AsnTrp: 0.531 ± 0.02	1.057AsnTyr: 1.057 ± 0.032	0.0AsnXaa: 0.0 ± 0.0
Pro	5.246ProAla: 5.246 ± 0.071	0.455ProCys: 0.455 ± 0.021	3.088ProAsp: 3.088 ± 0.048	3.134ProGlu: 3.134 ± 0.048	1.835ProPhe: 1.835 ± 0.033	3.553ProGly: 3.553 ± 0.06	1.149ProHis: 1.149 ± 0.035	1.925ProIle: 1.925 ± 0.048	1.318ProLys: 1.318 ± 0.039	5.402ProLeu: 5.402 ± 0.078	1.082ProMet: 1.082 ± 0.027	1.334ProAsn: 1.334 ± 0.034	1.982ProPro: 1.982 ± 0.044	2.298ProGln: 2.298 ± 0.04	2.153ProArg: 2.153 ± 0.04	2.582ProSer: 2.582 ± 0.044	2.295ProThr: 2.295 ± 0.046	3.944ProVal: 3.944 ± 0.062	0.691ProTrp: 0.691 ± 0.022	1.339ProTyr: 1.339 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	5.505GlnAla: 5.505 ± 0.078	0.406GlnCys: 0.406 ± 0.019	2.089GlnAsp: 2.089 ± 0.04	2.237GlnGlu: 2.237 ± 0.044	1.523GlnPhe: 1.523 ± 0.033	3.328GlnGly: 3.328 ± 0.071	1.401GlnHis: 1.401 ± 0.04	2.226GlnIle: 2.226 ± 0.041	1.569GlnLys: 1.569 ± 0.037	5.509GlnLeu: 5.509 ± 0.072	1.119GlnMet: 1.119 ± 0.03	1.376GlnAsn: 1.376 ± 0.034	2.605GlnPro: 2.605 ± 0.052	3.835GlnGln: 3.835 ± 0.079	3.605GlnArg: 3.605 ± 0.056	2.506GlnSer: 2.506 ± 0.046	2.443GlnThr: 2.443 ± 0.042	3.294GlnVal: 3.294 ± 0.052	0.701GlnTrp: 0.701 ± 0.025	1.175GlnTyr: 1.175 ± 0.031	0.0GlnXaa: 0.0 ± 0.0
Arg	5.034ArgAla: 5.034 ± 0.059	0.715ArgCys: 0.715 ± 0.024	3.253ArgAsp: 3.253 ± 0.052	3.674ArgGlu: 3.674 ± 0.051	2.766ArgPhe: 2.766 ± 0.044	3.516ArgGly: 3.516 ± 0.062	1.967ArgHis: 1.967 ± 0.041	3.656ArgIle: 3.656 ± 0.055	2.184ArgLys: 2.184 ± 0.046	7.501ArgLeu: 7.501 ± 0.087	1.584ArgMet: 1.584 ± 0.03	2.033ArgAsn: 2.033 ± 0.042	2.558ArgPro: 2.558 ± 0.049	4.168ArgGln: 4.168 ± 0.066	4.311ArgArg: 4.311 ± 0.078	3.062ArgSer: 3.062 ± 0.048	2.744ArgThr: 2.744 ± 0.043	4.137ArgVal: 4.137 ± 0.06	1.11ArgTrp: 1.11 ± 0.03	2.427ArgTyr: 2.427 ± 0.047	0.001ArgXaa: 0.001 ± 0.001
Ser	6.206SerAla: 6.206 ± 0.083	0.586SerCys: 0.586 ± 0.02	3.235SerAsp: 3.235 ± 0.058	2.934SerGlu: 2.934 ± 0.047	2.28SerPhe: 2.28 ± 0.04	5.491SerGly: 5.491 ± 0.072	1.499SerHis: 1.499 ± 0.033	2.935SerIle: 2.935 ± 0.053	1.76SerLys: 1.76 ± 0.034	7.45SerLeu: 7.45 ± 0.077	1.544SerMet: 1.544 ± 0.033	1.925SerAsn: 1.925 ± 0.04	2.91SerPro: 2.91 ± 0.05	2.787SerGln: 2.787 ± 0.048	3.882SerArg: 3.882 ± 0.057	3.938SerSer: 3.938 ± 0.073	3.06SerThr: 3.06 ± 0.056	4.408SerVal: 4.408 ± 0.062	0.919SerTrp: 0.919 ± 0.026	1.699SerTyr: 1.699 ± 0.032	0.001SerXaa: 0.001 ± 0.001
Thr	5.291ThrAla: 5.291 ± 0.113	0.468ThrCys: 0.468 ± 0.018	2.674ThrAsp: 2.674 ± 0.052	2.558ThrGlu: 2.558 ± 0.044	1.92ThrPhe: 1.92 ± 0.04	4.281ThrGly: 4.281 ± 0.069	1.261ThrHis: 1.261 ± 0.032	2.629ThrIle: 2.629 ± 0.042	1.322ThrLys: 1.322 ± 0.037	7.82ThrLeu: 7.82 ± 0.115	1.085ThrMet: 1.085 ± 0.028	1.507ThrAsn: 1.507 ± 0.04	3.419ThrPro: 3.419 ± 0.061	2.268ThrGln: 2.268 ± 0.04	3.22ThrArg: 3.22 ± 0.05	3.031ThrSer: 3.031 ± 0.051	2.885ThrThr: 2.885 ± 0.058	4.141ThrVal: 4.141 ± 0.106	0.64ThrTrp: 0.64 ± 0.023	1.241ThrTyr: 1.241 ± 0.042	0.0ThrXaa: 0.0 ± 0.0
Val	7.055ValAla: 7.055 ± 0.081	0.788ValCys: 0.788 ± 0.029	3.736ValAsp: 3.736 ± 0.055	3.691ValGlu: 3.691 ± 0.062	2.677ValPhe: 2.677 ± 0.057	4.806ValGly: 4.806 ± 0.061	1.212ValHis: 1.212 ± 0.029	4.307ValIle: 4.307 ± 0.06	2.727ValLys: 2.727 ± 0.051	7.356ValLeu: 7.356 ± 0.075	2.199ValMet: 2.199 ± 0.042	2.651ValAsn: 2.651 ± 0.05	2.993ValPro: 2.993 ± 0.053	2.49ValGln: 2.49 ± 0.041	3.963ValArg: 3.963 ± 0.058	4.93ValSer: 4.93 ± 0.061	4.299ValThr: 4.299 ± 0.094	5.558ValVal: 5.558 ± 0.077	0.921ValTrp: 0.921 ± 0.023	1.734ValTyr: 1.734 ± 0.037	0.002ValXaa: 0.002 ± 0.001
Trp	0.968TrpAla: 0.968 ± 0.029	0.174TrpCys: 0.174 ± 0.011	0.555TrpAsp: 0.555 ± 0.022	0.559TrpGlu: 0.559 ± 0.022	0.583TrpPhe: 0.583 ± 0.024	0.874TrpGly: 0.874 ± 0.024	0.438TrpHis: 0.438 ± 0.019	0.615TrpIle: 0.615 ± 0.021	0.456TrpLys: 0.456 ± 0.02	2.328TrpLeu: 2.328 ± 0.047	0.363TrpMet: 0.363 ± 0.017	0.463TrpAsn: 0.463 ± 0.017	0.653TrpPro: 0.653 ± 0.023	1.206TrpGln: 1.206 ± 0.034	1.168TrpArg: 1.168 ± 0.035	0.799TrpSer: 0.799 ± 0.027	0.472TrpThr: 0.472 ± 0.02	0.918TrpVal: 0.918 ± 0.023	0.244TrpTrp: 0.244 ± 0.013	0.389TrpTyr: 0.389 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.405TyrAla: 2.405 ± 0.045	0.387TyrCys: 0.387 ± 0.017	1.555TyrAsp: 1.555 ± 0.044	1.158TyrGlu: 1.158 ± 0.031	1.216TyrPhe: 1.216 ± 0.03	2.191TyrGly: 2.191 ± 0.042	0.807TyrHis: 0.807 ± 0.025	1.318TyrIle: 1.318 ± 0.034	0.824TyrLys: 0.824 ± 0.028	3.238TyrLeu: 3.238 ± 0.051	0.544TyrMet: 0.544 ± 0.021	0.963TyrAsn: 0.963 ± 0.031	1.502TyrPro: 1.502 ± 0.039	1.748TyrGln: 1.748 ± 0.042	2.193TyrArg: 2.193 ± 0.039	1.668TyrSer: 1.668 ± 0.036	1.4TyrThr: 1.4 ± 0.046	1.686TyrVal: 1.686 ± 0.035	0.431TyrTrp: 0.431 ± 0.019	0.903TyrTyr: 0.903 ± 0.03	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.002XaaAla: 0.002 ± 0.002	0.0XaaCys: 0.0 ± 0.0	0.001XaaAsp: 0.001 ± 0.001	0.001XaaGlu: 0.001 ± 0.001	0.002XaaPhe: 0.002 ± 0.001	0.001XaaGly: 0.001 ± 0.001	0.001XaaHis: 0.001 ± 0.001	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.001XaaLeu: 0.001 ± 0.001	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.001XaaVal: 0.001 ± 0.001	0.0XaaTrp: 0.0 ± 0.0	0.001XaaTyr: 0.001 ± 0.001	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4532 proteins (1412289 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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