Amino acid dipepetide frequency for Acinetobacter phage vB_AbaP_Acibel007

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.04AlaAla: 8.04 ± 0.911
0.451AlaCys: 0.451 ± 0.202
4.884AlaAsp: 4.884 ± 0.593
4.959AlaGlu: 4.959 ± 0.56
3.607AlaPhe: 3.607 ± 0.438
5.485AlaGly: 5.485 ± 0.711
1.803AlaHis: 1.803 ± 0.384
4.433AlaIle: 4.433 ± 0.59
6.161AlaLys: 6.161 ± 0.677
9.467AlaLeu: 9.467 ± 0.699
2.93AlaMet: 2.93 ± 0.507
4.133AlaAsn: 4.133 ± 0.485
2.404AlaPro: 2.404 ± 0.542
4.659AlaGln: 4.659 ± 0.592
2.63AlaArg: 2.63 ± 0.349
4.283AlaSer: 4.283 ± 0.655
5.034AlaThr: 5.034 ± 0.861
5.71AlaVal: 5.71 ± 0.742
0.902AlaTrp: 0.902 ± 0.25
3.832AlaTyr: 3.832 ± 0.482
0.0AlaXaa: 0.0 ± 0.0
Cys
0.601CysAla: 0.601 ± 0.275
0.225CysCys: 0.225 ± 0.123
0.301CysAsp: 0.301 ± 0.139
0.526CysGlu: 0.526 ± 0.228
0.451CysPhe: 0.451 ± 0.184
1.127CysGly: 1.127 ± 0.264
0.301CysHis: 0.301 ± 0.156
1.052CysIle: 1.052 ± 0.25
0.676CysLys: 0.676 ± 0.191
0.751CysLeu: 0.751 ± 0.23
0.451CysMet: 0.451 ± 0.197
0.827CysAsn: 0.827 ± 0.231
0.676CysPro: 0.676 ± 0.199
0.301CysGln: 0.301 ± 0.156
0.301CysArg: 0.301 ± 0.162
0.601CysSer: 0.601 ± 0.185
0.526CysThr: 0.526 ± 0.199
1.052CysVal: 1.052 ± 0.306
0.075CysTrp: 0.075 ± 0.068
0.601CysTyr: 0.601 ± 0.254
0.0CysXaa: 0.0 ± 0.0
Asp
5.184AspAla: 5.184 ± 0.679
1.127AspCys: 1.127 ± 0.345
3.682AspAsp: 3.682 ± 0.668
3.456AspGlu: 3.456 ± 0.528
1.954AspPhe: 1.954 ± 0.393
4.508AspGly: 4.508 ± 0.557
1.352AspHis: 1.352 ± 0.275
2.855AspIle: 2.855 ± 0.472
4.283AspLys: 4.283 ± 0.688
5.41AspLeu: 5.41 ± 0.747
2.329AspMet: 2.329 ± 0.371
2.78AspAsn: 2.78 ± 0.311
2.104AspPro: 2.104 ± 0.447
1.954AspGln: 1.954 ± 0.433
2.48AspArg: 2.48 ± 0.472
3.381AspSer: 3.381 ± 0.493
3.531AspThr: 3.531 ± 0.468
5.184AspVal: 5.184 ± 0.574
1.352AspTrp: 1.352 ± 0.352
3.381AspTyr: 3.381 ± 0.48
0.0AspXaa: 0.0 ± 0.0
Glu
7.363GluAla: 7.363 ± 0.767
0.526GluCys: 0.526 ± 0.18
3.757GluAsp: 3.757 ± 0.455
2.78GluGlu: 2.78 ± 0.543
2.705GluPhe: 2.705 ± 0.497
2.705GluGly: 2.705 ± 0.381
1.653GluHis: 1.653 ± 0.285
3.081GluIle: 3.081 ± 0.495
2.104GluLys: 2.104 ± 0.548
5.786GluLeu: 5.786 ± 0.595
1.428GluMet: 1.428 ± 0.329
2.63GluAsn: 2.63 ± 0.379
1.503GluPro: 1.503 ± 0.367
2.705GluGln: 2.705 ± 0.536
3.306GluArg: 3.306 ± 0.567
2.93GluSer: 2.93 ± 0.606
2.705GluThr: 2.705 ± 0.343
5.485GluVal: 5.485 ± 0.713
0.451GluTrp: 0.451 ± 0.166
2.404GluTyr: 2.404 ± 0.432
0.0GluXaa: 0.0 ± 0.0
Phe
2.855PheAla: 2.855 ± 0.366
0.676PheCys: 0.676 ± 0.234
2.404PheAsp: 2.404 ± 0.409
2.179PheGlu: 2.179 ± 0.375
1.352PhePhe: 1.352 ± 0.281
2.329PheGly: 2.329 ± 0.395
0.676PheHis: 0.676 ± 0.198
2.555PheIle: 2.555 ± 0.451
3.156PheLys: 3.156 ± 0.524
3.306PheLeu: 3.306 ± 0.544
1.352PheMet: 1.352 ± 0.248
1.803PheAsn: 1.803 ± 0.344
1.503PhePro: 1.503 ± 0.363
0.902PheGln: 0.902 ± 0.276
1.878PheArg: 1.878 ± 0.338
2.555PheSer: 2.555 ± 0.367
2.104PheThr: 2.104 ± 0.462
2.48PheVal: 2.48 ± 0.383
0.526PheTrp: 0.526 ± 0.203
0.526PheTyr: 0.526 ± 0.176
0.0PheXaa: 0.0 ± 0.0
Gly
4.734GlyAla: 4.734 ± 0.522
0.977GlyCys: 0.977 ± 0.27
3.982GlyAsp: 3.982 ± 0.453
4.057GlyGlu: 4.057 ± 0.448
2.705GlyPhe: 2.705 ± 0.486
5.335GlyGly: 5.335 ± 0.983
1.277GlyHis: 1.277 ± 0.327
4.959GlyIle: 4.959 ± 0.406
5.034GlyLys: 5.034 ± 0.678
6.086GlyLeu: 6.086 ± 0.833
2.029GlyMet: 2.029 ± 0.421
3.306GlyAsn: 3.306 ± 0.493
0.0GlyPro: 0.0 ± 0.0
3.231GlyGln: 3.231 ± 0.541
3.607GlyArg: 3.607 ± 0.531
4.433GlySer: 4.433 ± 0.512
6.011GlyThr: 6.011 ± 0.518
5.635GlyVal: 5.635 ± 0.648
0.977GlyTrp: 0.977 ± 0.291
2.404GlyTyr: 2.404 ± 0.448
0.0GlyXaa: 0.0 ± 0.0
His
1.052HisAla: 1.052 ± 0.312
0.526HisCys: 0.526 ± 0.224
1.653HisAsp: 1.653 ± 0.307
0.977HisGlu: 0.977 ± 0.301
0.676HisPhe: 0.676 ± 0.282
1.954HisGly: 1.954 ± 0.384
0.526HisHis: 0.526 ± 0.189
0.977HisIle: 0.977 ± 0.267
1.503HisLys: 1.503 ± 0.33
1.578HisLeu: 1.578 ± 0.357
0.601HisMet: 0.601 ± 0.276
0.902HisAsn: 0.902 ± 0.348
1.052HisPro: 1.052 ± 0.264
0.676HisGln: 0.676 ± 0.206
1.052HisArg: 1.052 ± 0.245
1.202HisSer: 1.202 ± 0.353
1.352HisThr: 1.352 ± 0.338
1.578HisVal: 1.578 ± 0.289
0.376HisTrp: 0.376 ± 0.169
0.977HisTyr: 0.977 ± 0.221
0.0HisXaa: 0.0 ± 0.0
Ile
3.757IleAla: 3.757 ± 0.561
0.526IleCys: 0.526 ± 0.201
4.208IleAsp: 4.208 ± 0.462
3.832IleGlu: 3.832 ± 0.643
0.977IlePhe: 0.977 ± 0.293
4.659IleGly: 4.659 ± 0.659
1.352IleHis: 1.352 ± 0.35
2.855IleIle: 2.855 ± 0.511
4.659IleLys: 4.659 ± 0.72
3.156IleLeu: 3.156 ± 0.454
1.277IleMet: 1.277 ± 0.258
3.306IleAsn: 3.306 ± 0.503
2.254IlePro: 2.254 ± 0.425
2.855IleGln: 2.855 ± 0.407
2.48IleArg: 2.48 ± 0.401
2.254IleSer: 2.254 ± 0.346
3.306IleThr: 3.306 ± 0.498
3.456IleVal: 3.456 ± 0.461
0.451IleTrp: 0.451 ± 0.18
1.653IleTyr: 1.653 ± 0.281
0.0IleXaa: 0.0 ± 0.0
Lys
6.387LysAla: 6.387 ± 0.72
0.676LysCys: 0.676 ± 0.203
4.508LysAsp: 4.508 ± 0.529
3.456LysGlu: 3.456 ± 0.556
1.728LysPhe: 1.728 ± 0.358
4.809LysGly: 4.809 ± 0.472
2.104LysHis: 2.104 ± 0.39
2.63LysIle: 2.63 ± 0.52
2.029LysLys: 2.029 ± 0.36
5.861LysLeu: 5.861 ± 0.733
1.428LysMet: 1.428 ± 0.393
3.081LysAsn: 3.081 ± 0.414
3.832LysPro: 3.832 ± 0.739
3.306LysGln: 3.306 ± 0.392
3.306LysArg: 3.306 ± 0.516
3.531LysSer: 3.531 ± 0.529
2.705LysThr: 2.705 ± 0.459
4.659LysVal: 4.659 ± 0.487
1.127LysTrp: 1.127 ± 0.316
2.63LysTyr: 2.63 ± 0.471
0.0LysXaa: 0.0 ± 0.0
Leu
7.514LeuAla: 7.514 ± 0.672
0.977LeuCys: 0.977 ± 0.323
6.236LeuAsp: 6.236 ± 0.686
4.508LeuGlu: 4.508 ± 0.399
2.48LeuPhe: 2.48 ± 0.427
6.612LeuGly: 6.612 ± 0.728
1.578LeuHis: 1.578 ± 0.355
3.982LeuIle: 3.982 ± 0.573
5.635LeuLys: 5.635 ± 0.707
7.514LeuLeu: 7.514 ± 0.885
1.803LeuMet: 1.803 ± 0.35
4.433LeuAsn: 4.433 ± 0.549
3.231LeuPro: 3.231 ± 0.464
3.907LeuGln: 3.907 ± 0.49
4.884LeuArg: 4.884 ± 0.435
5.936LeuSer: 5.936 ± 0.495
5.786LeuThr: 5.786 ± 0.414
5.71LeuVal: 5.71 ± 0.661
0.676LeuTrp: 0.676 ± 0.196
3.005LeuTyr: 3.005 ± 0.432
0.0LeuXaa: 0.0 ± 0.0
Met
1.728MetAla: 1.728 ± 0.368
0.301MetCys: 0.301 ± 0.146
1.503MetAsp: 1.503 ± 0.346
1.728MetGlu: 1.728 ± 0.288
1.052MetPhe: 1.052 ± 0.244
1.803MetGly: 1.803 ± 0.341
0.827MetHis: 0.827 ± 0.201
1.653MetIle: 1.653 ± 0.45
1.803MetLys: 1.803 ± 0.474
2.555MetLeu: 2.555 ± 0.441
0.751MetMet: 0.751 ± 0.212
1.202MetAsn: 1.202 ± 0.336
0.676MetPro: 0.676 ± 0.167
1.578MetGln: 1.578 ± 0.397
2.179MetArg: 2.179 ± 0.408
2.254MetSer: 2.254 ± 0.403
1.954MetThr: 1.954 ± 0.395
0.827MetVal: 0.827 ± 0.192
0.601MetTrp: 0.601 ± 0.168
1.578MetTyr: 1.578 ± 0.253
0.0MetXaa: 0.0 ± 0.0
Asn
4.433AsnAla: 4.433 ± 0.737
0.376AsnCys: 0.376 ± 0.125
3.156AsnAsp: 3.156 ± 0.403
3.081AsnGlu: 3.081 ± 0.518
1.728AsnPhe: 1.728 ± 0.35
4.133AsnGly: 4.133 ± 0.785
1.127AsnHis: 1.127 ± 0.31
3.607AsnIle: 3.607 ± 0.494
2.705AsnLys: 2.705 ± 0.282
4.057AsnLeu: 4.057 ± 0.537
1.578AsnMet: 1.578 ± 0.327
2.555AsnAsn: 2.555 ± 0.435
2.555AsnPro: 2.555 ± 0.459
2.104AsnGln: 2.104 ± 0.521
2.329AsnArg: 2.329 ± 0.616
2.63AsnSer: 2.63 ± 0.356
2.705AsnThr: 2.705 ± 0.422
3.231AsnVal: 3.231 ± 0.432
0.751AsnTrp: 0.751 ± 0.222
1.653AsnTyr: 1.653 ± 0.419
0.0AsnXaa: 0.0 ± 0.0
Pro
3.081ProAla: 3.081 ± 0.544
0.225ProCys: 0.225 ± 0.111
2.78ProAsp: 2.78 ± 0.287
3.607ProGlu: 3.607 ± 0.597
1.277ProPhe: 1.277 ± 0.238
0.0ProGly: 0.0 ± 0.0
0.676ProHis: 0.676 ± 0.183
1.878ProIle: 1.878 ± 0.437
2.254ProLys: 2.254 ± 0.384
3.156ProLeu: 3.156 ± 0.44
1.202ProMet: 1.202 ± 0.262
2.254ProAsn: 2.254 ± 0.32
0.902ProPro: 0.902 ± 0.281
1.728ProGln: 1.728 ± 0.398
0.827ProArg: 0.827 ± 0.193
1.578ProSer: 1.578 ± 0.302
2.404ProThr: 2.404 ± 0.346
2.93ProVal: 2.93 ± 0.506
0.225ProTrp: 0.225 ± 0.116
1.428ProTyr: 1.428 ± 0.332
0.0ProXaa: 0.0 ± 0.0
Gln
5.26GlnAla: 5.26 ± 0.806
0.376GlnCys: 0.376 ± 0.157
1.578GlnAsp: 1.578 ± 0.352
3.156GlnGlu: 3.156 ± 0.579
2.705GlnPhe: 2.705 ± 0.34
3.607GlnGly: 3.607 ± 0.586
0.902GlnHis: 0.902 ± 0.32
1.878GlnIle: 1.878 ± 0.308
1.803GlnLys: 1.803 ± 0.408
5.635GlnLeu: 5.635 ± 0.879
0.827GlnMet: 0.827 ± 0.239
1.728GlnAsn: 1.728 ± 0.257
1.503GlnPro: 1.503 ± 0.336
3.005GlnGln: 3.005 ± 0.555
2.63GlnArg: 2.63 ± 0.43
2.555GlnSer: 2.555 ± 0.483
2.179GlnThr: 2.179 ± 0.459
2.78GlnVal: 2.78 ± 0.389
0.526GlnTrp: 0.526 ± 0.202
2.254GlnTyr: 2.254 ± 0.499
0.0GlnXaa: 0.0 ± 0.0
Arg
2.78ArgAla: 2.78 ± 0.396
0.451ArgCys: 0.451 ± 0.256
3.081ArgAsp: 3.081 ± 0.448
2.48ArgGlu: 2.48 ± 0.436
2.104ArgPhe: 2.104 ± 0.273
2.93ArgGly: 2.93 ± 0.411
0.977ArgHis: 0.977 ± 0.24
2.48ArgIle: 2.48 ± 0.355
4.433ArgLys: 4.433 ± 0.569
4.283ArgLeu: 4.283 ± 0.428
1.653ArgMet: 1.653 ± 0.398
2.855ArgAsn: 2.855 ± 0.37
1.127ArgPro: 1.127 ± 0.198
1.428ArgGln: 1.428 ± 0.331
3.005ArgArg: 3.005 ± 0.546
3.005ArgSer: 3.005 ± 0.551
3.005ArgThr: 3.005 ± 0.384
3.156ArgVal: 3.156 ± 0.527
0.301ArgTrp: 0.301 ± 0.138
1.803ArgTyr: 1.803 ± 0.306
0.0ArgXaa: 0.0 ± 0.0
Ser
4.959SerAla: 4.959 ± 0.711
0.376SerCys: 0.376 ± 0.194
3.531SerAsp: 3.531 ± 0.426
3.081SerGlu: 3.081 ± 0.353
2.555SerPhe: 2.555 ± 0.482
4.583SerGly: 4.583 ± 0.603
0.376SerHis: 0.376 ± 0.156
2.93SerIle: 2.93 ± 0.518
3.381SerLys: 3.381 ± 0.488
4.208SerLeu: 4.208 ± 0.523
2.254SerMet: 2.254 ± 0.551
2.63SerAsn: 2.63 ± 0.456
2.029SerPro: 2.029 ± 0.383
3.005SerGln: 3.005 ± 0.61
2.179SerArg: 2.179 ± 0.292
3.832SerSer: 3.832 ± 0.698
4.133SerThr: 4.133 ± 0.515
3.832SerVal: 3.832 ± 0.551
0.376SerTrp: 0.376 ± 0.135
2.93SerTyr: 2.93 ± 0.44
0.0SerXaa: 0.0 ± 0.0
Thr
6.537ThrAla: 6.537 ± 0.838
0.676ThrCys: 0.676 ± 0.207
3.607ThrAsp: 3.607 ± 0.433
3.231ThrGlu: 3.231 ± 0.453
2.254ThrPhe: 2.254 ± 0.284
5.034ThrGly: 5.034 ± 0.659
1.052ThrHis: 1.052 ± 0.213
3.682ThrIle: 3.682 ± 0.433
3.081ThrLys: 3.081 ± 0.42
4.884ThrLeu: 4.884 ± 0.462
1.277ThrMet: 1.277 ± 0.253
2.555ThrAsn: 2.555 ± 0.401
3.081ThrPro: 3.081 ± 0.381
3.231ThrGln: 3.231 ± 0.352
2.93ThrArg: 2.93 ± 0.358
2.705ThrSer: 2.705 ± 0.349
3.456ThrThr: 3.456 ± 0.689
4.959ThrVal: 4.959 ± 0.718
0.526ThrTrp: 0.526 ± 0.18
2.63ThrTyr: 2.63 ± 0.425
0.0ThrXaa: 0.0 ± 0.0
Val
6.837ValAla: 6.837 ± 0.617
0.676ValCys: 0.676 ± 0.205
4.208ValAsp: 4.208 ± 0.654
3.531ValGlu: 3.531 ± 0.554
2.78ValPhe: 2.78 ± 0.467
5.71ValGly: 5.71 ± 0.546
1.578ValHis: 1.578 ± 0.368
3.231ValIle: 3.231 ± 0.544
5.41ValLys: 5.41 ± 0.673
4.508ValLeu: 4.508 ± 0.514
1.352ValMet: 1.352 ± 0.303
3.456ValAsn: 3.456 ± 0.396
2.78ValPro: 2.78 ± 0.461
3.832ValGln: 3.832 ± 0.559
2.93ValArg: 2.93 ± 0.477
4.433ValSer: 4.433 ± 0.656
5.184ValThr: 5.184 ± 0.848
4.884ValVal: 4.884 ± 0.654
0.751ValTrp: 0.751 ± 0.235
3.005ValTyr: 3.005 ± 0.444
0.0ValXaa: 0.0 ± 0.0
Trp
0.526TrpAla: 0.526 ± 0.151
0.376TrpCys: 0.376 ± 0.163
0.827TrpAsp: 0.827 ± 0.22
0.751TrpGlu: 0.751 ± 0.251
0.676TrpPhe: 0.676 ± 0.217
0.601TrpGly: 0.601 ± 0.217
0.301TrpHis: 0.301 ± 0.154
0.601TrpIle: 0.601 ± 0.202
0.902TrpLys: 0.902 ± 0.247
1.052TrpLeu: 1.052 ± 0.318
0.301TrpMet: 0.301 ± 0.15
0.977TrpAsn: 0.977 ± 0.216
0.0TrpPro: 0.0 ± 0.0
0.075TrpGln: 0.075 ± 0.066
0.451TrpArg: 0.451 ± 0.16
0.977TrpSer: 0.977 ± 0.208
0.676TrpThr: 0.676 ± 0.245
0.751TrpVal: 0.751 ± 0.224
0.075TrpTrp: 0.075 ± 0.074
0.676TrpTyr: 0.676 ± 0.201
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.179TyrAla: 2.179 ± 0.406
0.902TyrCys: 0.902 ± 0.228
2.404TyrAsp: 2.404 ± 0.342
2.63TyrGlu: 2.63 ± 0.451
1.352TyrPhe: 1.352 ± 0.376
2.855TyrGly: 2.855 ± 0.468
0.751TyrHis: 0.751 ± 0.24
1.954TyrIle: 1.954 ± 0.347
2.78TyrLys: 2.78 ± 0.526
3.156TyrLeu: 3.156 ± 0.395
1.653TyrMet: 1.653 ± 0.315
3.081TyrAsn: 3.081 ± 0.552
1.202TyrPro: 1.202 ± 0.219
2.404TyrGln: 2.404 ± 0.298
1.954TyrArg: 1.954 ± 0.475
2.179TyrSer: 2.179 ± 0.4
2.63TyrThr: 2.63 ± 0.441
2.78TyrVal: 2.78 ± 0.348
0.526TyrTrp: 0.526 ± 0.173
1.653TyrTyr: 1.653 ± 0.366
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 53 proteins (13310 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski