Amino acid dipepetide frequency for Bandicoot papillomatosis carcinomatosis virus type 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.51AlaAla: 2.51 ± 1.716
0.0AlaCys: 0.0 ± 0.0
4.184AlaAsp: 4.184 ± 1.282
1.674AlaGlu: 1.674 ± 0.417
1.674AlaPhe: 1.674 ± 1.295
0.0AlaGly: 0.0 ± 0.0
1.674AlaHis: 1.674 ± 0.92
5.021AlaIle: 5.021 ± 1.485
2.51AlaLys: 2.51 ± 1.724
1.674AlaLeu: 1.674 ± 0.92
1.674AlaMet: 1.674 ± 0.417
3.347AlaAsn: 3.347 ± 1.84
4.184AlaPro: 4.184 ± 2.176
1.674AlaGln: 1.674 ± 1.295
2.51AlaArg: 2.51 ± 0.768
0.837AlaSer: 0.837 ± 0.889
5.021AlaThr: 5.021 ± 1.621
2.51AlaVal: 2.51 ± 1.942
0.0AlaTrp: 0.0 ± 0.0
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
2.51CysAla: 2.51 ± 1.716
0.0CysCys: 0.0 ± 0.0
0.837CysAsp: 0.837 ± 0.889
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
1.674CysGly: 1.674 ± 0.92
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
1.674CysLys: 1.674 ± 1.149
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.837CysAsn: 0.837 ± 0.575
2.51CysPro: 2.51 ± 0.768
0.837CysGln: 0.837 ± 0.647
0.837CysArg: 0.837 ± 0.889
0.837CysSer: 0.837 ± 0.889
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.837CysTrp: 0.837 ± 0.575
1.674CysTyr: 1.674 ± 1.779
0.0CysXaa: 0.0 ± 0.0
Asp
4.184AspAla: 4.184 ± 2.176
0.837AspCys: 0.837 ± 0.575
1.674AspAsp: 1.674 ± 0.863
1.674AspGlu: 1.674 ± 0.92
5.858AspPhe: 5.858 ± 3.46
2.51AspGly: 2.51 ± 0.476
0.0AspHis: 0.0 ± 0.0
5.858AspIle: 5.858 ± 1.345
5.858AspLys: 5.858 ± 0.925
2.51AspLeu: 2.51 ± 0.476
1.674AspMet: 1.674 ± 0.92
4.184AspAsn: 4.184 ± 1.081
7.531AspPro: 7.531 ± 3.312
1.674AspGln: 1.674 ± 1.149
0.837AspArg: 0.837 ± 0.647
5.858AspSer: 5.858 ± 1.345
5.021AspThr: 5.021 ± 2.089
5.858AspVal: 5.858 ± 2.46
2.51AspTrp: 2.51 ± 1.716
0.837AspTyr: 0.837 ± 0.889
0.0AspXaa: 0.0 ± 0.0
Glu
3.347GluAla: 3.347 ± 1.727
0.837GluCys: 0.837 ± 0.889
7.531GluAsp: 7.531 ± 1.655
9.205GluGlu: 9.205 ± 1.018
1.674GluPhe: 1.674 ± 0.92
3.347GluGly: 3.347 ± 0.666
1.674GluHis: 1.674 ± 0.92
5.021GluIle: 5.021 ± 0.485
2.51GluLys: 2.51 ± 0.768
10.042GluLeu: 10.042 ± 0.94
0.837GluMet: 0.837 ± 0.647
2.51GluAsn: 2.51 ± 0.476
1.674GluPro: 1.674 ± 0.863
0.0GluGln: 0.0 ± 0.0
6.695GluArg: 6.695 ± 2.58
4.184GluSer: 4.184 ± 0.097
3.347GluThr: 3.347 ± 0.666
1.674GluVal: 1.674 ± 1.295
0.0GluTrp: 0.0 ± 0.0
1.674GluTyr: 1.674 ± 0.417
0.0GluXaa: 0.0 ± 0.0
Phe
1.674PheAla: 1.674 ± 0.417
1.674PheCys: 1.674 ± 1.779
2.51PheAsp: 2.51 ± 1.24
3.347PheGlu: 3.347 ± 0.835
0.837PhePhe: 0.837 ± 0.575
1.674PheGly: 1.674 ± 1.295
0.0PheHis: 0.0 ± 0.0
4.184PheIle: 4.184 ± 1.081
1.674PheLys: 1.674 ± 1.149
5.021PheLeu: 5.021 ± 0.485
0.0PheMet: 0.0 ± 0.0
3.347PheAsn: 3.347 ± 0.835
1.674PhePro: 1.674 ± 0.417
1.674PheGln: 1.674 ± 0.417
0.837PheArg: 0.837 ± 0.575
5.858PheSer: 5.858 ± 3.295
1.674PheThr: 1.674 ± 1.149
3.347PheVal: 3.347 ± 0.606
1.674PheTrp: 1.674 ± 1.149
2.51PheTyr: 2.51 ± 0.768
0.0PheXaa: 0.0 ± 0.0
Gly
2.51GlyAla: 2.51 ± 1.942
1.674GlyCys: 1.674 ± 0.92
5.858GlyAsp: 5.858 ± 2.044
3.347GlyGlu: 3.347 ± 0.606
2.51GlyPhe: 2.51 ± 1.716
14.226GlyGly: 14.226 ± 8.003
1.674GlyHis: 1.674 ± 0.92
1.674GlyIle: 1.674 ± 0.417
0.837GlyLys: 0.837 ± 0.575
2.51GlyLeu: 2.51 ± 0.926
0.0GlyMet: 0.0 ± 0.0
5.021GlyAsn: 5.021 ± 1.501
4.184GlyPro: 4.184 ± 2.451
3.347GlyGln: 3.347 ± 1.29
2.51GlyArg: 2.51 ± 0.476
6.695GlySer: 6.695 ± 0.941
5.858GlyThr: 5.858 ± 3.46
1.674GlyVal: 1.674 ± 1.149
0.0GlyTrp: 0.0 ± 0.0
1.674GlyTyr: 1.674 ± 0.417
0.0GlyXaa: 0.0 ± 0.0
His
0.837HisAla: 0.837 ± 0.575
1.674HisCys: 1.674 ± 1.779
0.837HisAsp: 0.837 ± 0.575
0.837HisGlu: 0.837 ± 0.647
0.837HisPhe: 0.837 ± 0.575
0.837HisGly: 0.837 ± 0.889
0.837HisHis: 0.837 ± 0.889
0.837HisIle: 0.837 ± 0.575
0.0HisLys: 0.0 ± 0.0
1.674HisLeu: 1.674 ± 0.863
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
2.51HisPro: 2.51 ± 0.476
0.0HisGln: 0.0 ± 0.0
0.837HisArg: 0.837 ± 0.647
0.0HisSer: 0.0 ± 0.0
0.837HisThr: 0.837 ± 0.889
1.674HisVal: 1.674 ± 0.417
0.837HisTrp: 0.837 ± 0.575
0.837HisTyr: 0.837 ± 0.889
0.0HisXaa: 0.0 ± 0.0
Ile
0.837IleAla: 0.837 ± 0.647
1.674IleCys: 1.674 ± 1.149
6.695IleAsp: 6.695 ± 3.114
5.858IleGlu: 5.858 ± 1.345
3.347IlePhe: 3.347 ± 0.666
6.695IleGly: 6.695 ± 1.992
0.0IleHis: 0.0 ± 0.0
3.347IleIle: 3.347 ± 1.542
3.347IleLys: 3.347 ± 1.84
5.858IleLeu: 5.858 ± 1.666
1.674IleMet: 1.674 ± 0.907
6.695IleAsn: 6.695 ± 0.672
2.51IlePro: 2.51 ± 0.926
0.837IleGln: 0.837 ± 0.575
0.0IleArg: 0.0 ± 0.0
3.347IleSer: 3.347 ± 0.835
3.347IleThr: 3.347 ± 0.666
2.51IleVal: 2.51 ± 1.942
0.837IleTrp: 0.837 ± 0.575
2.51IleTyr: 2.51 ± 1.24
0.0IleXaa: 0.0 ± 0.0
Lys
4.184LysAla: 4.184 ± 2.23
0.0LysCys: 0.0 ± 0.0
3.347LysAsp: 3.347 ± 0.606
5.021LysGlu: 5.021 ± 2.77
2.51LysPhe: 2.51 ± 0.768
1.674LysGly: 1.674 ± 0.92
0.0LysHis: 0.0 ± 0.0
3.347LysIle: 3.347 ± 0.835
5.021LysLys: 5.021 ± 2.481
3.347LysLeu: 3.347 ± 1.364
3.347LysMet: 3.347 ± 1.786
1.674LysAsn: 1.674 ± 1.779
3.347LysPro: 3.347 ± 0.835
0.837LysGln: 0.837 ± 0.575
6.695LysArg: 6.695 ± 0.545
4.184LysSer: 4.184 ± 1.094
3.347LysThr: 3.347 ± 1.29
2.51LysVal: 2.51 ± 1.724
0.0LysTrp: 0.0 ± 0.0
3.347LysTyr: 3.347 ± 0.606
0.0LysXaa: 0.0 ± 0.0
Leu
2.51LeuAla: 2.51 ± 0.768
0.837LeuCys: 0.837 ± 0.575
6.695LeuAsp: 6.695 ± 0.545
10.042LeuGlu: 10.042 ± 2.234
6.695LeuPhe: 6.695 ± 3.428
5.858LeuGly: 5.858 ± 1.059
2.51LeuHis: 2.51 ± 1.942
1.674LeuIle: 1.674 ± 0.863
4.184LeuLys: 4.184 ± 1.314
5.858LeuLeu: 5.858 ± 0.96
1.674LeuMet: 1.674 ± 0.863
5.858LeuAsn: 5.858 ± 1.855
3.347LeuPro: 3.347 ± 0.835
3.347LeuGln: 3.347 ± 1.542
2.51LeuArg: 2.51 ± 0.926
3.347LeuSer: 3.347 ± 2.59
2.51LeuThr: 2.51 ± 0.476
5.021LeuVal: 5.021 ± 1.535
0.0LeuTrp: 0.0 ± 0.0
3.347LeuTyr: 3.347 ± 0.835
0.0LeuXaa: 0.0 ± 0.0
Met
0.837MetAla: 0.837 ± 0.575
0.0MetCys: 0.0 ± 0.0
3.347MetAsp: 3.347 ± 1.364
0.837MetGlu: 0.837 ± 0.647
1.674MetPhe: 1.674 ± 0.92
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
1.674MetIle: 1.674 ± 0.92
1.674MetLys: 1.674 ± 1.779
0.837MetLeu: 0.837 ± 0.575
0.0MetMet: 0.0 ± 0.0
0.837MetAsn: 0.837 ± 0.889
0.0MetPro: 0.0 ± 0.0
1.674MetGln: 1.674 ± 0.417
1.674MetArg: 1.674 ± 1.295
1.674MetSer: 1.674 ± 0.417
0.837MetThr: 0.837 ± 0.575
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.347AsnAla: 3.347 ± 0.666
1.674AsnCys: 1.674 ± 0.417
0.837AsnAsp: 0.837 ± 0.575
0.837AsnGlu: 0.837 ± 0.889
4.184AsnPhe: 4.184 ± 2.23
1.674AsnGly: 1.674 ± 1.149
1.674AsnHis: 1.674 ± 1.779
3.347AsnIle: 3.347 ± 0.666
5.858AsnLys: 5.858 ± 3.018
3.347AsnLeu: 3.347 ± 1.29
1.674AsnMet: 1.674 ± 0.417
6.695AsnAsn: 6.695 ± 0.672
5.858AsnPro: 5.858 ± 2.46
3.347AsnGln: 3.347 ± 0.606
2.51AsnArg: 2.51 ± 1.25
3.347AsnSer: 3.347 ± 0.606
7.531AsnThr: 7.531 ± 2.303
5.858AsnVal: 5.858 ± 0.925
0.837AsnTrp: 0.837 ± 0.889
4.184AsnTyr: 4.184 ± 1.314
0.0AsnXaa: 0.0 ± 0.0
Pro
2.51ProAla: 2.51 ± 0.926
0.0ProCys: 0.0 ± 0.0
10.042ProAsp: 10.042 ± 1.999
5.858ProGlu: 5.858 ± 1.345
1.674ProPhe: 1.674 ± 1.295
3.347ProGly: 3.347 ± 0.666
0.0ProHis: 0.0 ± 0.0
3.347ProIle: 3.347 ± 1.542
4.184ProLys: 4.184 ± 1.094
9.205ProLeu: 9.205 ± 2.261
0.837ProMet: 0.837 ± 0.647
5.021ProAsn: 5.021 ± 1.535
5.021ProPro: 5.021 ± 0.485
1.674ProGln: 1.674 ± 0.863
2.51ProArg: 2.51 ± 0.768
9.205ProSer: 9.205 ± 1.49
2.51ProThr: 2.51 ± 0.926
2.51ProVal: 2.51 ± 0.926
0.0ProTrp: 0.0 ± 0.0
2.51ProTyr: 2.51 ± 1.724
0.0ProXaa: 0.0 ± 0.0
Gln
0.0GlnAla: 0.0 ± 0.0
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
0.0GlnGlu: 0.0 ± 0.0
0.837GlnPhe: 0.837 ± 0.647
0.837GlnGly: 0.837 ± 0.575
0.0GlnHis: 0.0 ± 0.0
3.347GlnIle: 3.347 ± 1.78
2.51GlnLys: 2.51 ± 0.768
3.347GlnLeu: 3.347 ± 0.666
1.674GlnMet: 1.674 ± 1.149
3.347GlnAsn: 3.347 ± 0.606
1.674GlnPro: 1.674 ± 1.149
0.0GlnGln: 0.0 ± 0.0
0.837GlnArg: 0.837 ± 0.575
2.51GlnSer: 2.51 ± 0.476
2.51GlnThr: 2.51 ± 0.926
0.837GlnVal: 0.837 ± 0.647
0.837GlnTrp: 0.837 ± 0.889
4.184GlnTyr: 4.184 ± 1.094
0.0GlnXaa: 0.0 ± 0.0
Arg
0.837ArgAla: 0.837 ± 0.647
0.837ArgCys: 0.837 ± 0.575
0.837ArgAsp: 0.837 ± 0.647
0.837ArgGlu: 0.837 ± 0.575
2.51ArgPhe: 2.51 ± 0.768
3.347ArgGly: 3.347 ± 1.29
2.51ArgHis: 2.51 ± 1.25
4.184ArgIle: 4.184 ± 1.094
5.858ArgLys: 5.858 ± 1.059
4.184ArgLeu: 4.184 ± 0.097
0.837ArgMet: 0.837 ± 0.575
4.184ArgAsn: 4.184 ± 1.225
5.021ArgPro: 5.021 ± 0.7
0.837ArgGln: 0.837 ± 0.575
4.184ArgArg: 4.184 ± 2.176
3.347ArgSer: 3.347 ± 0.666
1.674ArgThr: 1.674 ± 0.417
3.347ArgVal: 3.347 ± 1.542
0.0ArgTrp: 0.0 ± 0.0
1.674ArgTyr: 1.674 ± 0.863
0.0ArgXaa: 0.0 ± 0.0
Ser
5.021SerAla: 5.021 ± 0.951
0.837SerCys: 0.837 ± 0.889
5.858SerAsp: 5.858 ± 0.925
5.021SerGlu: 5.021 ± 0.7
0.837SerPhe: 0.837 ± 0.889
6.695SerGly: 6.695 ± 1.713
2.51SerHis: 2.51 ± 0.476
8.368SerIle: 8.368 ± 4.353
0.837SerLys: 0.837 ± 0.575
6.695SerLeu: 6.695 ± 1.633
0.0SerMet: 0.0 ± 0.656
5.858SerAsn: 5.858 ± 1.059
1.674SerPro: 1.674 ± 1.295
3.347SerGln: 3.347 ± 1.84
3.347SerArg: 3.347 ± 2.59
10.042SerSer: 10.042 ± 1.947
3.347SerThr: 3.347 ± 0.835
3.347SerVal: 3.347 ± 1.542
0.0SerTrp: 0.0 ± 0.0
1.674SerTyr: 1.674 ± 1.779
0.0SerXaa: 0.0 ± 0.0
Thr
0.0ThrAla: 0.0 ± 0.0
2.51ThrCys: 2.51 ± 0.476
0.837ThrAsp: 0.837 ± 0.647
7.531ThrGlu: 7.531 ± 0.759
3.347ThrPhe: 3.347 ± 0.666
5.858ThrGly: 5.858 ± 2.46
0.0ThrHis: 0.0 ± 0.0
4.184ThrIle: 4.184 ± 1.225
4.184ThrLys: 4.184 ± 1.844
4.184ThrLeu: 4.184 ± 1.27
0.0ThrMet: 0.0 ± 0.0
0.837ThrAsn: 0.837 ± 0.575
7.531ThrPro: 7.531 ± 0.759
0.0ThrGln: 0.0 ± 0.0
3.347ThrArg: 3.347 ± 1.29
1.674ThrSer: 1.674 ± 0.417
6.695ThrThr: 6.695 ± 1.633
8.368ThrVal: 8.368 ± 2.087
0.0ThrTrp: 0.0 ± 0.0
3.347ThrTyr: 3.347 ± 1.714
0.0ThrXaa: 0.0 ± 0.0
Val
3.347ValAla: 3.347 ± 0.835
0.0ValCys: 0.0 ± 0.0
2.51ValAsp: 2.51 ± 0.926
2.51ValGlu: 2.51 ± 0.768
3.347ValPhe: 3.347 ± 0.835
3.347ValGly: 3.347 ± 1.29
0.0ValHis: 0.0 ± 0.0
1.674ValIle: 1.674 ± 1.295
3.347ValLys: 3.347 ± 1.78
1.674ValLeu: 1.674 ± 1.149
0.0ValMet: 0.0 ± 0.0
5.021ValAsn: 5.021 ± 0.7
8.368ValPro: 8.368 ± 2.087
2.51ValGln: 2.51 ± 1.942
2.51ValArg: 2.51 ± 0.926
5.858ValSer: 5.858 ± 0.376
4.184ValThr: 4.184 ± 3.237
2.51ValVal: 2.51 ± 0.926
0.837ValTrp: 0.837 ± 0.575
0.837ValTyr: 0.837 ± 0.575
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.837TrpAsp: 0.837 ± 0.575
0.837TrpGlu: 0.837 ± 0.889
0.0TrpPhe: 0.0 ± 0.0
0.837TrpGly: 0.837 ± 0.575
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.837TrpLeu: 0.837 ± 0.575
0.0TrpMet: 0.0 ± 0.0
0.837TrpAsn: 0.837 ± 0.575
0.0TrpPro: 0.0 ± 0.0
1.674TrpGln: 1.674 ± 0.92
0.0TrpArg: 0.0 ± 0.0
2.51TrpSer: 2.51 ± 1.716
1.674TrpThr: 1.674 ± 1.149
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.674TyrAla: 1.674 ± 1.149
0.0TyrCys: 0.0 ± 0.0
1.674TyrAsp: 1.674 ± 0.92
2.51TyrGlu: 2.51 ± 1.716
0.837TyrPhe: 0.837 ± 0.575
3.347TyrGly: 3.347 ± 0.606
1.674TyrHis: 1.674 ± 0.417
0.837TyrIle: 0.837 ± 0.575
1.674TyrLys: 1.674 ± 0.417
5.021TyrLeu: 5.021 ± 1.485
0.837TyrMet: 0.837 ± 0.889
2.51TyrAsn: 2.51 ± 1.25
3.347TyrPro: 3.347 ± 0.835
0.0TyrGln: 0.0 ± 0.0
5.858TyrArg: 5.858 ± 0.925
0.837TyrSer: 0.837 ± 0.647
2.51TyrThr: 2.51 ± 1.716
0.837TyrVal: 0.837 ± 0.647
0.837TyrTrp: 0.837 ± 0.575
0.837TyrTyr: 0.837 ± 0.575
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1196 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski