Amino acid dipepetide frequency for Wuhan aphid virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.345AlaAla: 4.345 ± 2.471
0.0AlaCys: 0.0 ± 0.0
1.337AlaAsp: 1.337 ± 0.729
2.34AlaGlu: 2.34 ± 0.231
3.008AlaPhe: 3.008 ± 1.329
2.674AlaGly: 2.674 ± 0.665
2.34AlaHis: 2.34 ± 0.75
2.005AlaIle: 2.005 ± 0.464
2.005AlaLys: 2.005 ± 0.745
10.361AlaLeu: 10.361 ± 2.856
3.008AlaMet: 3.008 ± 0.674
2.34AlaAsn: 2.34 ± 0.933
2.005AlaPro: 2.005 ± 0.628
3.008AlaGln: 3.008 ± 1.148
3.008AlaArg: 3.008 ± 0.669
6.684AlaSer: 6.684 ± 0.847
3.342AlaThr: 3.342 ± 1.131
2.005AlaVal: 2.005 ± 0.453
1.337AlaTrp: 1.337 ± 0.756
4.345AlaTyr: 4.345 ± 1.163
0.0AlaXaa: 0.0 ± 0.0
Cys
0.668CysAla: 0.668 ± 0.464
0.334CysCys: 0.334 ± 0.23
0.668CysAsp: 0.668 ± 0.263
0.668CysGlu: 0.668 ± 0.536
0.668CysPhe: 0.668 ± 0.339
1.003CysGly: 1.003 ± 0.478
0.334CysHis: 0.334 ± 0.23
1.003CysIle: 1.003 ± 0.478
0.334CysLys: 0.334 ± 0.327
1.337CysLeu: 1.337 ± 0.894
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.668CysPro: 0.668 ± 0.456
0.668CysGln: 0.668 ± 0.536
0.668CysArg: 0.668 ± 0.536
2.005CysSer: 2.005 ± 0.833
1.003CysThr: 1.003 ± 0.464
1.337CysVal: 1.337 ± 0.504
0.0CysTrp: 0.0 ± 0.0
1.003CysTyr: 1.003 ± 0.335
0.0CysXaa: 0.0 ± 0.0
Asp
3.008AspAla: 3.008 ± 1.618
0.668AspCys: 0.668 ± 0.456
3.676AspAsp: 3.676 ± 0.492
3.008AspGlu: 3.008 ± 1.27
1.003AspPhe: 1.003 ± 0.396
1.003AspGly: 1.003 ± 0.613
1.337AspHis: 1.337 ± 0.481
5.013AspIle: 5.013 ± 1.606
3.342AspLys: 3.342 ± 0.933
4.345AspLeu: 4.345 ± 0.947
2.005AspMet: 2.005 ± 0.468
1.671AspAsn: 1.671 ± 0.669
1.671AspPro: 1.671 ± 0.804
2.005AspGln: 2.005 ± 0.354
1.337AspArg: 1.337 ± 0.742
2.005AspSer: 2.005 ± 0.554
5.013AspThr: 5.013 ± 0.933
4.345AspVal: 4.345 ± 1.027
1.671AspTrp: 1.671 ± 0.504
1.003AspTyr: 1.003 ± 0.69
0.0AspXaa: 0.0 ± 0.0
Glu
2.34GluAla: 2.34 ± 0.535
1.003GluCys: 1.003 ± 0.559
2.34GluAsp: 2.34 ± 0.801
3.676GluGlu: 3.676 ± 0.889
2.34GluPhe: 2.34 ± 0.902
1.671GluGly: 1.671 ± 0.487
0.334GluHis: 0.334 ± 0.334
3.676GluIle: 3.676 ± 0.893
3.676GluLys: 3.676 ± 0.764
5.348GluLeu: 5.348 ± 1.719
1.671GluMet: 1.671 ± 0.355
3.008GluAsn: 3.008 ± 0.724
1.671GluPro: 1.671 ± 0.606
1.337GluGln: 1.337 ± 0.633
3.342GluArg: 3.342 ± 1.065
3.008GluSer: 3.008 ± 0.513
5.348GluThr: 5.348 ± 1.29
2.674GluVal: 2.674 ± 1.026
0.334GluTrp: 0.334 ± 0.335
0.668GluTyr: 0.668 ± 0.464
0.0GluXaa: 0.0 ± 0.0
Phe
1.671PheAla: 1.671 ± 0.428
0.668PheCys: 0.668 ± 0.466
3.008PheAsp: 3.008 ± 0.655
1.337PheGlu: 1.337 ± 0.511
1.337PhePhe: 1.337 ± 0.481
5.348PheGly: 5.348 ± 1.423
0.334PheHis: 0.334 ± 0.327
1.003PheIle: 1.003 ± 0.478
1.671PheLys: 1.671 ± 0.337
6.016PheLeu: 6.016 ± 0.975
1.671PheMet: 1.671 ± 0.825
2.34PheAsn: 2.34 ± 1.022
1.337PhePro: 1.337 ± 0.439
0.334PheGln: 0.334 ± 0.268
1.003PheArg: 1.003 ± 0.446
4.011PheSer: 4.011 ± 0.499
3.008PheThr: 3.008 ± 0.245
3.342PheVal: 3.342 ± 0.671
0.668PheTrp: 0.668 ± 0.536
2.674PheTyr: 2.674 ± 0.665
0.0PheXaa: 0.0 ± 0.0
Gly
2.674GlyAla: 2.674 ± 1.083
0.334GlyCys: 0.334 ± 0.268
2.674GlyAsp: 2.674 ± 0.878
2.674GlyGlu: 2.674 ± 0.68
4.345GlyPhe: 4.345 ± 1.81
4.679GlyGly: 4.679 ± 1.318
2.34GlyHis: 2.34 ± 0.647
4.679GlyIle: 4.679 ± 0.987
4.679GlyLys: 4.679 ± 1.013
8.69GlyLeu: 8.69 ± 1.345
2.34GlyMet: 2.34 ± 0.546
2.674GlyAsn: 2.674 ± 0.638
4.345GlyPro: 4.345 ± 0.776
2.34GlyGln: 2.34 ± 0.77
6.684GlyArg: 6.684 ± 1.359
3.676GlySer: 3.676 ± 0.917
2.34GlyThr: 2.34 ± 0.75
4.345GlyVal: 4.345 ± 1.165
0.668GlyTrp: 0.668 ± 0.32
3.008GlyTyr: 3.008 ± 0.813
0.0GlyXaa: 0.0 ± 0.0
His
1.337HisAla: 1.337 ± 0.31
0.0HisCys: 0.0 ± 0.0
1.671HisAsp: 1.671 ± 0.45
2.674HisGlu: 2.674 ± 0.531
3.342HisPhe: 3.342 ± 0.688
1.337HisGly: 1.337 ± 0.838
1.003HisHis: 1.003 ± 0.522
0.668HisIle: 0.668 ± 0.46
0.334HisLys: 0.334 ± 0.23
1.337HisLeu: 1.337 ± 0.439
0.668HisMet: 0.668 ± 0.441
1.337HisAsn: 1.337 ± 0.743
0.334HisPro: 0.334 ± 0.268
1.003HisGln: 1.003 ± 0.522
1.003HisArg: 1.003 ± 0.223
2.34HisSer: 2.34 ± 0.951
1.003HisThr: 1.003 ± 0.543
2.34HisVal: 2.34 ± 0.902
1.003HisTrp: 1.003 ± 0.522
2.34HisTyr: 2.34 ± 0.839
0.334HisXaa: 0.334 ± 0.327
Ile
5.682IleAla: 5.682 ± 0.992
2.005IleCys: 2.005 ± 0.706
1.671IleAsp: 1.671 ± 0.337
2.674IleGlu: 2.674 ± 0.602
1.671IlePhe: 1.671 ± 1.259
4.345IleGly: 4.345 ± 1.198
0.668IleHis: 0.668 ± 0.37
3.342IleIle: 3.342 ± 0.602
3.676IleLys: 3.676 ± 0.834
6.35IleLeu: 6.35 ± 1.762
1.671IleMet: 1.671 ± 0.41
3.342IleAsn: 3.342 ± 0.224
5.013IlePro: 5.013 ± 0.751
2.674IleGln: 2.674 ± 1.051
3.676IleArg: 3.676 ± 0.944
4.345IleSer: 4.345 ± 1.016
6.016IleThr: 6.016 ± 1.486
3.676IleVal: 3.676 ± 1.032
1.337IleTrp: 1.337 ± 0.934
2.674IleTyr: 2.674 ± 0.906
0.0IleXaa: 0.0 ± 0.0
Lys
2.674LysAla: 2.674 ± 0.474
0.668LysCys: 0.668 ± 0.339
2.674LysAsp: 2.674 ± 0.297
2.005LysGlu: 2.005 ± 0.843
1.003LysPhe: 1.003 ± 0.575
5.682LysGly: 5.682 ± 0.703
1.337LysHis: 1.337 ± 0.526
5.013LysIle: 5.013 ± 1.488
2.674LysLys: 2.674 ± 1.027
3.676LysLeu: 3.676 ± 1.088
2.005LysMet: 2.005 ± 0.622
1.671LysAsn: 1.671 ± 0.818
3.008LysPro: 3.008 ± 1.166
2.674LysGln: 2.674 ± 0.417
3.008LysArg: 3.008 ± 0.694
0.668LysSer: 0.668 ± 0.263
5.682LysThr: 5.682 ± 1.463
2.005LysVal: 2.005 ± 0.83
1.003LysTrp: 1.003 ± 0.464
2.674LysTyr: 2.674 ± 1.06
0.0LysXaa: 0.0 ± 0.0
Leu
6.35LeuAla: 6.35 ± 2.105
1.671LeuCys: 1.671 ± 0.285
3.676LeuAsp: 3.676 ± 0.91
4.345LeuGlu: 4.345 ± 1.369
5.348LeuPhe: 5.348 ± 1.435
6.35LeuGly: 6.35 ± 1.194
3.342LeuHis: 3.342 ± 0.973
4.679LeuIle: 4.679 ± 1.485
6.35LeuLys: 6.35 ± 0.689
12.032LeuLeu: 12.032 ± 1.297
5.013LeuMet: 5.013 ± 1.047
3.008LeuAsn: 3.008 ± 0.608
4.345LeuPro: 4.345 ± 0.873
2.674LeuGln: 2.674 ± 0.862
6.016LeuArg: 6.016 ± 1.16
6.684LeuSer: 6.684 ± 0.809
10.695LeuThr: 10.695 ± 1.838
4.011LeuVal: 4.011 ± 0.86
0.334LeuTrp: 0.334 ± 0.335
3.676LeuTyr: 3.676 ± 1.062
0.0LeuXaa: 0.0 ± 0.0
Met
1.671MetAla: 1.671 ± 0.54
0.668MetCys: 0.668 ± 0.362
1.003MetAsp: 1.003 ± 0.415
1.003MetGlu: 1.003 ± 0.522
2.34MetPhe: 2.34 ± 0.959
1.671MetGly: 1.671 ± 0.703
1.337MetHis: 1.337 ± 0.729
6.016MetIle: 6.016 ± 1.517
3.008MetLys: 3.008 ± 0.733
2.674MetLeu: 2.674 ± 1.129
0.668MetMet: 0.668 ± 0.32
1.671MetAsn: 1.671 ± 0.624
0.668MetPro: 0.668 ± 0.46
1.003MetGln: 1.003 ± 0.478
2.34MetArg: 2.34 ± 0.91
0.334MetSer: 0.334 ± 0.23
1.671MetThr: 1.671 ± 0.488
3.342MetVal: 3.342 ± 0.761
0.334MetTrp: 0.334 ± 0.334
0.668MetTyr: 0.668 ± 0.466
0.0MetXaa: 0.0 ± 0.0
Asn
2.34AsnAla: 2.34 ± 0.858
0.334AsnCys: 0.334 ± 0.268
0.668AsnAsp: 0.668 ± 0.42
2.005AsnGlu: 2.005 ± 0.928
1.003AsnPhe: 1.003 ± 0.559
1.671AsnGly: 1.671 ± 1.045
1.337AsnHis: 1.337 ± 0.92
2.34AsnIle: 2.34 ± 0.733
2.34AsnLys: 2.34 ± 1.027
2.005AsnLeu: 2.005 ± 0.535
0.0AsnMet: 0.0 ± 0.0
2.005AsnAsn: 2.005 ± 1.045
3.342AsnPro: 3.342 ± 0.761
0.668AsnGln: 0.668 ± 0.435
2.005AsnArg: 2.005 ± 0.446
3.008AsnSer: 3.008 ± 0.76
3.676AsnThr: 3.676 ± 0.849
3.008AsnVal: 3.008 ± 0.587
2.34AsnTrp: 2.34 ± 0.431
1.671AsnTyr: 1.671 ± 0.45
0.0AsnXaa: 0.0 ± 0.0
Pro
2.005ProAla: 2.005 ± 0.554
1.671ProCys: 1.671 ± 0.445
1.003ProAsp: 1.003 ± 0.804
2.005ProGlu: 2.005 ± 0.957
1.337ProPhe: 1.337 ± 0.252
5.013ProGly: 5.013 ± 0.642
1.671ProHis: 1.671 ± 0.542
3.008ProIle: 3.008 ± 0.531
2.34ProLys: 2.34 ± 0.784
3.676ProLeu: 3.676 ± 0.492
1.003ProMet: 1.003 ± 0.389
1.003ProAsn: 1.003 ± 0.415
1.671ProPro: 1.671 ± 0.652
2.34ProGln: 2.34 ± 0.607
2.34ProArg: 2.34 ± 0.91
2.674ProSer: 2.674 ± 0.353
3.008ProThr: 3.008 ± 1.044
4.011ProVal: 4.011 ± 0.755
1.671ProTrp: 1.671 ± 0.405
2.674ProTyr: 2.674 ± 1.088
0.0ProXaa: 0.0 ± 0.0
Gln
3.676GlnAla: 3.676 ± 1.187
0.334GlnCys: 0.334 ± 0.327
2.005GlnAsp: 2.005 ± 0.595
1.671GlnGlu: 1.671 ± 0.641
1.671GlnPhe: 1.671 ± 0.656
4.345GlnGly: 4.345 ± 1.09
0.334GlnHis: 0.334 ± 0.23
3.008GlnIle: 3.008 ± 1.006
2.005GlnLys: 2.005 ± 1.252
2.005GlnLeu: 2.005 ± 0.829
0.0GlnMet: 0.0 ± 0.0
0.334GlnAsn: 0.334 ± 0.23
1.671GlnPro: 1.671 ± 0.321
1.337GlnGln: 1.337 ± 0.673
2.005GlnArg: 2.005 ± 0.486
1.337GlnSer: 1.337 ± 0.252
2.674GlnThr: 2.674 ± 0.329
2.34GlnVal: 2.34 ± 0.673
1.003GlnTrp: 1.003 ± 0.335
1.337GlnTyr: 1.337 ± 0.252
0.0GlnXaa: 0.0 ± 0.0
Arg
1.671ArgAla: 1.671 ± 0.907
0.0ArgCys: 0.0 ± 0.0
3.676ArgAsp: 3.676 ± 1.076
3.676ArgGlu: 3.676 ± 1.085
1.003ArgPhe: 1.003 ± 0.223
4.011ArgGly: 4.011 ± 0.777
1.337ArgHis: 1.337 ± 0.934
4.345ArgIle: 4.345 ± 1.598
2.005ArgLys: 2.005 ± 0.652
5.682ArgLeu: 5.682 ± 1.099
2.34ArgMet: 2.34 ± 0.651
3.008ArgAsn: 3.008 ± 1.322
2.34ArgPro: 2.34 ± 0.414
3.008ArgGln: 3.008 ± 0.773
4.011ArgArg: 4.011 ± 1.208
3.008ArgSer: 3.008 ± 0.601
2.34ArgThr: 2.34 ± 1.204
3.676ArgVal: 3.676 ± 0.956
0.668ArgTrp: 0.668 ± 0.542
2.674ArgTyr: 2.674 ± 0.888
0.0ArgXaa: 0.0 ± 0.0
Ser
2.005SerAla: 2.005 ± 0.708
1.003SerCys: 1.003 ± 0.415
3.676SerAsp: 3.676 ± 1.366
3.676SerGlu: 3.676 ± 1.004
3.342SerPhe: 3.342 ± 0.806
4.345SerGly: 4.345 ± 0.527
2.34SerHis: 2.34 ± 0.622
3.676SerIle: 3.676 ± 0.33
2.005SerLys: 2.005 ± 0.701
8.021SerLeu: 8.021 ± 1.021
1.337SerMet: 1.337 ± 0.659
2.34SerAsn: 2.34 ± 0.556
2.005SerPro: 2.005 ± 0.7
1.671SerGln: 1.671 ± 0.907
3.676SerArg: 3.676 ± 0.845
1.003SerSer: 1.003 ± 0.451
5.348SerThr: 5.348 ± 0.988
4.011SerVal: 4.011 ± 2.01
1.337SerTrp: 1.337 ± 0.465
1.003SerTyr: 1.003 ± 0.442
0.0SerXaa: 0.0 ± 0.0
Thr
8.021ThrAla: 8.021 ± 0.963
0.668ThrCys: 0.668 ± 0.435
4.011ThrAsp: 4.011 ± 0.811
2.674ThrGlu: 2.674 ± 0.671
2.674ThrPhe: 2.674 ± 1.024
6.016ThrGly: 6.016 ± 1.478
3.342ThrHis: 3.342 ± 1.014
5.348ThrIle: 5.348 ± 1.022
3.008ThrLys: 3.008 ± 0.608
5.682ThrLeu: 5.682 ± 0.777
2.34ThrMet: 2.34 ± 0.702
2.005ThrAsn: 2.005 ± 0.964
3.342ThrPro: 3.342 ± 0.767
2.34ThrGln: 2.34 ± 0.345
3.676ThrArg: 3.676 ± 0.948
5.013ThrSer: 5.013 ± 1.408
6.35ThrThr: 6.35 ± 0.803
3.342ThrVal: 3.342 ± 0.837
0.668ThrTrp: 0.668 ± 0.339
5.348ThrTyr: 5.348 ± 2.367
0.0ThrXaa: 0.0 ± 0.0
Val
4.345ValAla: 4.345 ± 0.753
1.337ValCys: 1.337 ± 0.792
4.345ValAsp: 4.345 ± 0.994
2.34ValGlu: 2.34 ± 0.556
3.008ValPhe: 3.008 ± 0.399
6.35ValGly: 6.35 ± 0.934
1.003ValHis: 1.003 ± 0.396
4.011ValIle: 4.011 ± 0.454
3.008ValLys: 3.008 ± 0.633
5.013ValLeu: 5.013 ± 1.489
3.008ValMet: 3.008 ± 0.538
2.005ValAsn: 2.005 ± 0.559
3.676ValPro: 3.676 ± 0.687
2.005ValGln: 2.005 ± 0.446
1.003ValArg: 1.003 ± 0.532
2.005ValSer: 2.005 ± 0.622
3.676ValThr: 3.676 ± 0.57
3.342ValVal: 3.342 ± 0.753
1.671ValTrp: 1.671 ± 0.677
2.674ValTyr: 2.674 ± 0.87
0.0ValXaa: 0.0 ± 0.0
Trp
1.337TrpAla: 1.337 ± 0.673
0.334TrpCys: 0.334 ± 0.335
1.003TrpAsp: 1.003 ± 0.63
1.337TrpGlu: 1.337 ± 0.484
0.334TrpPhe: 0.334 ± 0.334
0.668TrpGly: 0.668 ± 0.32
0.0TrpHis: 0.0 ± 0.0
1.337TrpIle: 1.337 ± 0.87
1.671TrpLys: 1.671 ± 0.777
2.005TrpLeu: 2.005 ± 0.7
1.003TrpMet: 1.003 ± 0.223
0.668TrpAsn: 0.668 ± 0.401
1.003TrpPro: 1.003 ± 0.647
0.668TrpGln: 0.668 ± 0.37
1.671TrpArg: 1.671 ± 0.321
0.668TrpSer: 0.668 ± 0.464
1.003TrpThr: 1.003 ± 0.415
0.668TrpVal: 0.668 ± 0.32
0.334TrpTrp: 0.334 ± 0.334
1.003TrpTyr: 1.003 ± 0.559
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.676TyrAla: 3.676 ± 0.935
0.668TyrCys: 0.668 ± 0.371
4.345TyrAsp: 4.345 ± 1.331
3.676TyrGlu: 3.676 ± 1.267
2.005TyrPhe: 2.005 ± 0.554
2.005TyrGly: 2.005 ± 0.446
1.337TyrHis: 1.337 ± 0.634
2.674TyrIle: 2.674 ± 1.158
1.671TyrLys: 1.671 ± 0.542
4.345TyrLeu: 4.345 ± 1.084
2.005TyrMet: 2.005 ± 0.354
1.337TyrAsn: 1.337 ± 0.439
2.005TyrPro: 2.005 ± 0.96
1.337TyrGln: 1.337 ± 0.522
2.005TyrArg: 2.005 ± 0.339
3.008TyrSer: 3.008 ± 0.466
2.674TyrThr: 2.674 ± 0.998
2.005TyrVal: 2.005 ± 0.948
0.334TyrTrp: 0.334 ± 0.23
2.34TyrTyr: 2.34 ± 0.81
0.334TyrXaa: 0.334 ± 0.327
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.334XaaSer: 0.334 ± 0.327
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.334XaaTyr: 0.334 ± 0.327
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2993 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski