Amino acid dipepetide frequency for Arthrobacter ulcerisalmonis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	22.043AlaAla: 22.043 ± 0.218	0.749AlaCys: 0.749 ± 0.029	7.812AlaAsp: 7.812 ± 0.095	7.975AlaGlu: 7.975 ± 0.111	3.689AlaPhe: 3.689 ± 0.066	13.245AlaGly: 13.245 ± 0.135	2.364AlaHis: 2.364 ± 0.045	5.419AlaIle: 5.419 ± 0.082	3.931AlaLys: 3.931 ± 0.069	13.261AlaLeu: 13.261 ± 0.132	2.822AlaMet: 2.822 ± 0.056	3.058AlaAsn: 3.058 ± 0.055	6.326AlaPro: 6.326 ± 0.106	4.16AlaGln: 4.16 ± 0.072	7.283AlaArg: 7.283 ± 0.087	7.359AlaSer: 7.359 ± 0.086	7.608AlaThr: 7.608 ± 0.095	11.595AlaVal: 11.595 ± 0.112	1.651AlaTrp: 1.651 ± 0.045	2.245AlaTyr: 2.245 ± 0.053	0.0AlaXaa: 0.0 ± 0.0
Cys	0.695CysAla: 0.695 ± 0.024	0.07CysCys: 0.07 ± 0.008	0.317CysAsp: 0.317 ± 0.017	0.291CysGlu: 0.291 ± 0.016	0.193CysPhe: 0.193 ± 0.013	0.663CysGly: 0.663 ± 0.024	0.12CysHis: 0.12 ± 0.012	0.232CysIle: 0.232 ± 0.015	0.104CysLys: 0.104 ± 0.009	0.569CysLeu: 0.569 ± 0.025	0.093CysMet: 0.093 ± 0.009	0.134CysAsn: 0.134 ± 0.012	0.34CysPro: 0.34 ± 0.023	0.165CysGln: 0.165 ± 0.014	0.389CysArg: 0.389 ± 0.018	0.405CysSer: 0.405 ± 0.022	0.394CysThr: 0.394 ± 0.022	0.437CysVal: 0.437 ± 0.021	0.092CysTrp: 0.092 ± 0.01	0.145CysTyr: 0.145 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	7.504AspAla: 7.504 ± 0.09	0.304AspCys: 0.304 ± 0.018	3.096AspAsp: 3.096 ± 0.059	3.124AspGlu: 3.124 ± 0.063	1.921AspPhe: 1.921 ± 0.047	5.609AspGly: 5.609 ± 0.086	1.224AspHis: 1.224 ± 0.032	2.366AspIle: 2.366 ± 0.05	1.36AspLys: 1.36 ± 0.039	5.784AspLeu: 5.784 ± 0.083	0.915AspMet: 0.915 ± 0.031	1.121AspAsn: 1.121 ± 0.034	3.628AspPro: 3.628 ± 0.064	1.986AspGln: 1.986 ± 0.048	3.361AspArg: 3.361 ± 0.056	2.919AspSer: 2.919 ± 0.051	2.812AspThr: 2.812 ± 0.054	4.995AspVal: 4.995 ± 0.067	0.845AspTrp: 0.845 ± 0.03	1.277AspTyr: 1.277 ± 0.037	0.0AspXaa: 0.0 ± 0.0
Glu	6.698GluAla: 6.698 ± 0.103	0.278GluCys: 0.278 ± 0.016	2.653GluAsp: 2.653 ± 0.059	2.901GluGlu: 2.901 ± 0.055	1.726GluPhe: 1.726 ± 0.043	3.596GluGly: 3.596 ± 0.061	1.378GluHis: 1.378 ± 0.037	2.53GluIle: 2.53 ± 0.053	1.678GluLys: 1.678 ± 0.049	6.679GluLeu: 6.679 ± 0.092	0.954GluMet: 0.954 ± 0.034	1.404GluAsn: 1.404 ± 0.039	2.826GluPro: 2.826 ± 0.065	2.23GluGln: 2.23 ± 0.047	3.783GluArg: 3.783 ± 0.059	3.089GluSer: 3.089 ± 0.052	2.898GluThr: 2.898 ± 0.052	4.143GluVal: 4.143 ± 0.065	0.751GluTrp: 0.751 ± 0.029	1.053GluTyr: 1.053 ± 0.034	0.0GluXaa: 0.0 ± 0.0
Phe	4.163PheAla: 4.163 ± 0.06	0.254PheCys: 0.254 ± 0.015	2.085PheAsp: 2.085 ± 0.049	1.651PheGlu: 1.651 ± 0.042	1.18PhePhe: 1.18 ± 0.039	3.422PheGly: 3.422 ± 0.057	0.609PheHis: 0.609 ± 0.025	1.348PheIle: 1.348 ± 0.04	0.802PheLys: 0.802 ± 0.03	3.024PheLeu: 3.024 ± 0.06	0.588PheMet: 0.588 ± 0.028	0.903PheAsn: 0.903 ± 0.029	1.464PhePro: 1.464 ± 0.041	0.864PheGln: 0.864 ± 0.036	1.803PheArg: 1.803 ± 0.044	1.987PheSer: 1.987 ± 0.042	2.148PheThr: 2.148 ± 0.05	2.539PheVal: 2.539 ± 0.048	0.484PheTrp: 0.484 ± 0.021	0.7PheTyr: 0.7 ± 0.025	0.0PheXaa: 0.0 ± 0.0
Gly	10.281GlyAla: 10.281 ± 0.112	0.608GlyCys: 0.608 ± 0.021	4.046GlyAsp: 4.046 ± 0.077	4.232GlyGlu: 4.232 ± 0.069	3.262GlyPhe: 3.262 ± 0.055	7.292GlyGly: 7.292 ± 0.11	1.964GlyHis: 1.964 ± 0.045	4.718GlyIle: 4.718 ± 0.077	3.018GlyLys: 3.018 ± 0.053	9.255GlyLeu: 9.255 ± 0.109	2.01GlyMet: 2.01 ± 0.043	2.253GlyAsn: 2.253 ± 0.049	4.045GlyPro: 4.045 ± 0.076	3.177GlyGln: 3.177 ± 0.063	5.582GlyArg: 5.582 ± 0.074	5.884GlySer: 5.884 ± 0.08	6.189GlyThr: 6.189 ± 0.086	7.35GlyVal: 7.35 ± 0.096	1.556GlyTrp: 1.556 ± 0.039	2.168GlyTyr: 2.168 ± 0.044	0.0GlyXaa: 0.0 ± 0.0
His	2.317HisAla: 2.317 ± 0.048	0.155HisCys: 0.155 ± 0.014	1.184HisAsp: 1.184 ± 0.036	1.099HisGlu: 1.099 ± 0.032	0.671HisPhe: 0.671 ± 0.026	1.953HisGly: 1.953 ± 0.049	0.652HisHis: 0.652 ± 0.029	0.786HisIle: 0.786 ± 0.027	0.423HisLys: 0.423 ± 0.023	2.152HisLeu: 2.152 ± 0.045	0.34HisMet: 0.34 ± 0.021	0.434HisAsn: 0.434 ± 0.02	1.408HisPro: 1.408 ± 0.037	0.763HisGln: 0.763 ± 0.029	1.518HisArg: 1.518 ± 0.038	1.15HisSer: 1.15 ± 0.033	1.044HisThr: 1.044 ± 0.036	1.634HisVal: 1.634 ± 0.039	0.298HisTrp: 0.298 ± 0.016	0.465HisTyr: 0.465 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	5.972IleAla: 5.972 ± 0.086	0.303IleCys: 0.303 ± 0.017	2.687IleAsp: 2.687 ± 0.049	2.349IleGlu: 2.349 ± 0.05	1.45IlePhe: 1.45 ± 0.039	4.074IleGly: 4.074 ± 0.066	0.805IleHis: 0.805 ± 0.028	1.989IleIle: 1.989 ± 0.054	1.178IleLys: 1.178 ± 0.033	4.098IleLeu: 4.098 ± 0.075	0.798IleMet: 0.798 ± 0.027	1.309IleAsn: 1.309 ± 0.035	2.49IlePro: 2.49 ± 0.056	1.232IleGln: 1.232 ± 0.033	2.774IleArg: 2.774 ± 0.059	2.844IleSer: 2.844 ± 0.057	2.887IleThr: 2.887 ± 0.056	3.602IleVal: 3.602 ± 0.058	0.513IleTrp: 0.513 ± 0.021	0.861IleTyr: 0.861 ± 0.028	0.0IleXaa: 0.0 ± 0.0
Lys	3.668LysAla: 3.668 ± 0.07	0.104LysCys: 0.104 ± 0.011	1.817LysAsp: 1.817 ± 0.046	1.409LysGlu: 1.409 ± 0.035	0.794LysPhe: 0.794 ± 0.032	2.044LysGly: 2.044 ± 0.047	0.538LysHis: 0.538 ± 0.021	1.41LysIle: 1.41 ± 0.037	1.039LysLys: 1.039 ± 0.041	2.657LysLeu: 2.657 ± 0.058	0.59LysMet: 0.59 ± 0.026	0.786LysAsn: 0.786 ± 0.029	1.654LysPro: 1.654 ± 0.04	0.838LysGln: 0.838 ± 0.026	1.652LysArg: 1.652 ± 0.046	1.599LysSer: 1.599 ± 0.042	1.689LysThr: 1.689 ± 0.038	2.402LysVal: 2.402 ± 0.053	0.28LysTrp: 0.28 ± 0.018	0.623LysTyr: 0.623 ± 0.025	0.0LysXaa: 0.0 ± 0.0
Leu	15.388LeuAla: 15.388 ± 0.142	0.594LeuCys: 0.594 ± 0.024	6.132LeuAsp: 6.132 ± 0.077	5.073LeuGlu: 5.073 ± 0.086	2.939LeuPhe: 2.939 ± 0.062	9.175LeuGly: 9.175 ± 0.113	1.972LeuHis: 1.972 ± 0.048	4.448LeuIle: 4.448 ± 0.072	2.617LeuLys: 2.617 ± 0.054	10.677LeuLeu: 10.677 ± 0.136	1.935LeuMet: 1.935 ± 0.047	2.583LeuAsn: 2.583 ± 0.047	5.795LeuPro: 5.795 ± 0.074	3.017LeuGln: 3.017 ± 0.049	6.783LeuArg: 6.783 ± 0.091	6.072LeuSer: 6.072 ± 0.083	6.505LeuThr: 6.505 ± 0.08	8.733LeuVal: 8.733 ± 0.104	1.243LeuTrp: 1.243 ± 0.043	1.67LeuTyr: 1.67 ± 0.038	0.0LeuXaa: 0.0 ± 0.0
Met	2.666MetAla: 2.666 ± 0.048	0.112MetCys: 0.112 ± 0.01	0.999MetAsp: 0.999 ± 0.028	0.84MetGlu: 0.84 ± 0.028	0.602MetPhe: 0.602 ± 0.024	1.664MetGly: 1.664 ± 0.04	0.307MetHis: 0.307 ± 0.016	0.864MetIle: 0.864 ± 0.032	0.554MetLys: 0.554 ± 0.022	1.904MetLeu: 1.904 ± 0.045	0.382MetMet: 0.382 ± 0.022	0.579MetAsn: 0.579 ± 0.026	1.108MetPro: 1.108 ± 0.03	0.565MetGln: 0.565 ± 0.023	1.119MetArg: 1.119 ± 0.033	1.502MetSer: 1.502 ± 0.035	1.624MetThr: 1.624 ± 0.039	1.676MetVal: 1.676 ± 0.039	0.208MetTrp: 0.208 ± 0.012	0.302MetTyr: 0.302 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	2.948AsnAla: 2.948 ± 0.061	0.153AsnCys: 0.153 ± 0.013	1.322AsnAsp: 1.322 ± 0.041	1.165AsnGlu: 1.165 ± 0.037	0.83AsnPhe: 0.83 ± 0.03	2.429AsnGly: 2.429 ± 0.046	0.567AsnHis: 0.567 ± 0.023	1.113AsnIle: 1.113 ± 0.036	0.68AsnLys: 0.68 ± 0.025	2.413AsnLeu: 2.413 ± 0.049	0.454AsnMet: 0.454 ± 0.022	0.765AsnAsn: 0.765 ± 0.029	1.884AsnPro: 1.884 ± 0.046	0.909AsnGln: 0.909 ± 0.029	1.596AsnArg: 1.596 ± 0.038	1.423AsnSer: 1.423 ± 0.043	1.431AsnThr: 1.431 ± 0.036	1.994AsnVal: 1.994 ± 0.045	0.39AsnTrp: 0.39 ± 0.018	0.592AsnTyr: 0.592 ± 0.025	0.0AsnXaa: 0.0 ± 0.0
Pro	8.205ProAla: 8.205 ± 0.113	0.212ProCys: 0.212 ± 0.014	3.572ProAsp: 3.572 ± 0.061	3.746ProGlu: 3.746 ± 0.055	1.647ProPhe: 1.647 ± 0.04	5.282ProGly: 5.282 ± 0.078	1.083ProHis: 1.083 ± 0.038	1.81ProIle: 1.81 ± 0.046	1.361ProLys: 1.361 ± 0.037	5.045ProLeu: 5.045 ± 0.074	1.006ProMet: 1.006 ± 0.031	1.227ProAsn: 1.227 ± 0.036	2.067ProPro: 2.067 ± 0.059	1.804ProGln: 1.804 ± 0.044	2.817ProArg: 2.817 ± 0.056	3.278ProSer: 3.278 ± 0.059	3.218ProThr: 3.218 ± 0.062	4.793ProVal: 4.793 ± 0.081	0.77ProTrp: 0.77 ± 0.032	0.997ProTyr: 0.997 ± 0.03	0.0ProXaa: 0.0 ± 0.0
Gln	4.189GlnAla: 4.189 ± 0.071	0.155GlnCys: 0.155 ± 0.013	1.79GlnAsp: 1.79 ± 0.045	1.729GlnGlu: 1.729 ± 0.037	0.933GlnPhe: 0.933 ± 0.03	2.529GlnGly: 2.529 ± 0.047	0.832GlnHis: 0.832 ± 0.028	1.533GlnIle: 1.533 ± 0.039	0.84GlnLys: 0.84 ± 0.026	3.861GlnLeu: 3.861 ± 0.066	0.634GlnMet: 0.634 ± 0.023	0.744GlnAsn: 0.744 ± 0.029	2.083GlnPro: 2.083 ± 0.051	1.555GlnGln: 1.555 ± 0.049	2.599GlnArg: 2.599 ± 0.054	1.672GlnSer: 1.672 ± 0.041	1.608GlnThr: 1.608 ± 0.037	2.628GlnVal: 2.628 ± 0.05	0.513GlnTrp: 0.513 ± 0.021	0.701GlnTyr: 0.701 ± 0.029	0.0GlnXaa: 0.0 ± 0.0
Arg	6.794ArgAla: 6.794 ± 0.087	0.377ArgCys: 0.377 ± 0.019	3.409ArgAsp: 3.409 ± 0.065	3.576ArgGlu: 3.576 ± 0.06	2.118ArgPhe: 2.118 ± 0.047	4.531ArgGly: 4.531 ± 0.065	1.508ArgHis: 1.508 ± 0.036	3.173ArgIle: 3.173 ± 0.055	1.981ArgLys: 1.981 ± 0.047	6.588ArgLeu: 6.588 ± 0.089	1.358ArgMet: 1.358 ± 0.037	1.737ArgAsn: 1.737 ± 0.044	3.22ArgPro: 3.22 ± 0.063	2.346ArgGln: 2.346 ± 0.056	5.136ArgArg: 5.136 ± 0.085	3.893ArgSer: 3.893 ± 0.06	3.987ArgThr: 3.987 ± 0.067	4.581ArgVal: 4.581 ± 0.075	1.0ArgTrp: 1.0 ± 0.032	1.438ArgTyr: 1.438 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	7.856SerAla: 7.856 ± 0.095	0.316SerCys: 0.316 ± 0.017	2.854SerAsp: 2.854 ± 0.054	2.71SerGlu: 2.71 ± 0.048	2.09SerPhe: 2.09 ± 0.038	5.986SerGly: 5.986 ± 0.079	1.124SerHis: 1.124 ± 0.036	2.568SerIle: 2.568 ± 0.051	1.499SerLys: 1.499 ± 0.044	5.923SerLeu: 5.923 ± 0.073	1.41SerMet: 1.41 ± 0.033	1.501SerAsn: 1.501 ± 0.039	3.277SerPro: 3.277 ± 0.055	1.905SerGln: 1.905 ± 0.046	3.707SerArg: 3.707 ± 0.058	3.834SerSer: 3.834 ± 0.067	3.884SerThr: 3.884 ± 0.07	4.935SerVal: 4.935 ± 0.075	0.935SerTrp: 0.935 ± 0.029	1.371SerTyr: 1.371 ± 0.043	0.0SerXaa: 0.0 ± 0.0
Thr	8.37ThrAla: 8.37 ± 0.099	0.316ThrCys: 0.316 ± 0.016	3.355ThrAsp: 3.355 ± 0.055	3.165ThrGlu: 3.165 ± 0.064	1.965ThrPhe: 1.965 ± 0.04	5.759ThrGly: 5.759 ± 0.079	1.12ThrHis: 1.12 ± 0.038	2.627ThrIle: 2.627 ± 0.049	1.64ThrLys: 1.64 ± 0.043	5.99ThrLeu: 5.99 ± 0.078	1.068ThrMet: 1.068 ± 0.033	1.442ThrAsn: 1.442 ± 0.038	3.879ThrPro: 3.879 ± 0.079	1.719ThrGln: 1.719 ± 0.042	3.207ThrArg: 3.207 ± 0.054	3.626ThrSer: 3.626 ± 0.066	3.755ThrThr: 3.755 ± 0.072	5.868ThrVal: 5.868 ± 0.085	0.785ThrTrp: 0.785 ± 0.027	1.229ThrTyr: 1.229 ± 0.03	0.0ThrXaa: 0.0 ± 0.0
Val	11.086ValAla: 11.086 ± 0.129	0.507ValCys: 0.507 ± 0.022	5.103ValAsp: 5.103 ± 0.077	4.596ValGlu: 4.596 ± 0.074	2.648ValPhe: 2.648 ± 0.051	6.762ValGly: 6.762 ± 0.096	1.679ValHis: 1.679 ± 0.042	3.919ValIle: 3.919 ± 0.058	2.026ValLys: 2.026 ± 0.047	9.413ValLeu: 9.413 ± 0.115	1.651ValMet: 1.651 ± 0.039	2.09ValAsn: 2.09 ± 0.043	4.747ValPro: 4.747 ± 0.08	2.524ValGln: 2.524 ± 0.049	5.2ValArg: 5.2 ± 0.075	5.07ValSer: 5.07 ± 0.08	5.215ValThr: 5.215 ± 0.072	8.093ValVal: 8.093 ± 0.111	0.965ValTrp: 0.965 ± 0.029	1.405ValTyr: 1.405 ± 0.033	0.0ValXaa: 0.0 ± 0.0
Trp	1.511TrpAla: 1.511 ± 0.04	0.125TrpCys: 0.125 ± 0.011	0.767TrpAsp: 0.767 ± 0.03	0.605TrpGlu: 0.605 ± 0.026	0.55TrpPhe: 0.55 ± 0.028	0.929TrpGly: 0.929 ± 0.031	0.296TrpHis: 0.296 ± 0.017	0.659TrpIle: 0.659 ± 0.024	0.387TrpLys: 0.387 ± 0.02	1.815TrpLeu: 1.815 ± 0.045	0.279TrpMet: 0.279 ± 0.017	0.446TrpAsn: 0.446 ± 0.019	0.647TrpPro: 0.647 ± 0.025	0.635TrpGln: 0.635 ± 0.026	0.971TrpArg: 0.971 ± 0.031	0.795TrpSer: 0.795 ± 0.029	0.841TrpThr: 0.841 ± 0.034	1.086TrpVal: 1.086 ± 0.037	0.305TrpTrp: 0.305 ± 0.018	0.276TrpTyr: 0.276 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.241TyrAla: 2.241 ± 0.046	0.155TyrCys: 0.155 ± 0.013	1.15TyrAsp: 1.15 ± 0.036	1.014TyrGlu: 1.014 ± 0.032	0.809TyrPhe: 0.809 ± 0.026	1.948TyrGly: 1.948 ± 0.039	0.303TyrHis: 0.303 ± 0.017	0.703TyrIle: 0.703 ± 0.027	0.475TyrLys: 0.475 ± 0.024	2.239TyrLeu: 2.239 ± 0.054	0.289TyrMet: 0.289 ± 0.018	0.543TyrAsn: 0.543 ± 0.023	1.053TyrPro: 1.053 ± 0.031	0.734TyrGln: 0.734 ± 0.025	1.47TyrArg: 1.47 ± 0.04	1.285TyrSer: 1.285 ± 0.033	1.15TyrThr: 1.15 ± 0.039	1.615TyrVal: 1.615 ± 0.037	0.339TyrTrp: 0.339 ± 0.018	0.483TyrTyr: 0.483 ± 0.023	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3300 proteins (1050411 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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