Amino acid dipepetide frequency for Ectocarpus siliculosus virus 1 (isolate New Zealand/Kaikoura/1988) (EsV-1)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.977AlaAla: 6.977 ± 0.553
1.65AlaCys: 1.65 ± 0.148
4.976AlaAsp: 4.976 ± 0.306
4.259AlaGlu: 4.259 ± 0.367
3.069AlaPhe: 3.069 ± 0.235
4.922AlaGly: 4.922 ± 0.439
1.69AlaHis: 1.69 ± 0.131
3.367AlaIle: 3.367 ± 0.21
5.098AlaLys: 5.098 ± 0.394
6.342AlaLeu: 6.342 ± 0.346
2.245AlaMet: 2.245 ± 0.178
2.65AlaAsn: 2.65 ± 0.194
2.894AlaPro: 2.894 ± 0.371
2.042AlaGln: 2.042 ± 0.196
4.719AlaArg: 4.719 ± 0.347
6.761AlaSer: 6.761 ± 0.365
4.854AlaThr: 4.854 ± 0.328
4.868AlaVal: 4.868 ± 0.256
0.69AlaTrp: 0.69 ± 0.104
2.177AlaTyr: 2.177 ± 0.17
0.0AlaXaa: 0.0 ± 0.0
Cys
1.866CysAla: 1.866 ± 0.177
0.608CysCys: 0.608 ± 0.086
1.041CysAsp: 1.041 ± 0.124
1.055CysGlu: 1.055 ± 0.12
1.014CysPhe: 1.014 ± 0.123
1.582CysGly: 1.582 ± 0.182
0.69CysHis: 0.69 ± 0.122
0.933CysIle: 0.933 ± 0.123
0.771CysLys: 0.771 ± 0.11
2.055CysLeu: 2.055 ± 0.188
0.446CysMet: 0.446 ± 0.079
0.744CysAsn: 0.744 ± 0.114
1.149CysPro: 1.149 ± 0.124
0.46CysGln: 0.46 ± 0.088
1.23CysArg: 1.23 ± 0.14
1.758CysSer: 1.758 ± 0.159
1.203CysThr: 1.203 ± 0.112
1.717CysVal: 1.717 ± 0.168
0.162CysTrp: 0.162 ± 0.043
0.433CysTyr: 0.433 ± 0.087
0.0CysXaa: 0.0 ± 0.0
Asp
4.881AspAla: 4.881 ± 0.261
1.068AspCys: 1.068 ± 0.132
4.787AspAsp: 4.787 ± 0.37
3.678AspGlu: 3.678 ± 0.269
2.501AspPhe: 2.501 ± 0.196
4.57AspGly: 4.57 ± 0.347
1.258AspHis: 1.258 ± 0.111
3.637AspIle: 3.637 ± 0.234
2.961AspLys: 2.961 ± 0.183
5.084AspLeu: 5.084 ± 0.278
1.988AspMet: 1.988 ± 0.138
2.163AspAsn: 2.163 ± 0.184
2.718AspPro: 2.718 ± 0.189
1.609AspGln: 1.609 ± 0.165
3.205AspArg: 3.205 ± 0.219
4.665AspSer: 4.665 ± 0.388
3.935AspThr: 3.935 ± 0.235
5.003AspVal: 5.003 ± 0.287
0.446AspTrp: 0.446 ± 0.073
1.298AspTyr: 1.298 ± 0.161
0.0AspXaa: 0.0 ± 0.0
Glu
4.273GluAla: 4.273 ± 0.364
0.892GluCys: 0.892 ± 0.121
3.083GluAsp: 3.083 ± 0.282
4.8GluGlu: 4.8 ± 0.544
2.474GluPhe: 2.474 ± 0.217
3.191GluGly: 3.191 ± 0.274
1.393GluHis: 1.393 ± 0.168
3.935GluIle: 3.935 ± 0.265
4.246GluLys: 4.246 ± 0.386
4.503GluLeu: 4.503 ± 0.311
1.541GluMet: 1.541 ± 0.17
2.894GluAsn: 2.894 ± 0.192
1.487GluPro: 1.487 ± 0.162
2.218GluGln: 2.218 ± 0.232
3.489GluArg: 3.489 ± 0.253
4.165GluSer: 4.165 ± 0.407
3.867GluThr: 3.867 ± 0.252
3.827GluVal: 3.827 ± 0.261
0.892GluTrp: 0.892 ± 0.124
1.893GluTyr: 1.893 ± 0.17
0.0GluXaa: 0.0 ± 0.0
Phe
2.826PheAla: 2.826 ± 0.17
0.987PheCys: 0.987 ± 0.135
2.785PheAsp: 2.785 ± 0.205
2.177PheGlu: 2.177 ± 0.171
2.245PhePhe: 2.245 ± 0.209
2.961PheGly: 2.961 ± 0.234
1.176PheHis: 1.176 ± 0.141
1.907PheIle: 1.907 ± 0.161
2.326PheLys: 2.326 ± 0.193
3.164PheLeu: 3.164 ± 0.187
0.838PheMet: 0.838 ± 0.096
1.379PheAsn: 1.379 ± 0.161
1.839PhePro: 1.839 ± 0.192
1.46PheGln: 1.46 ± 0.143
2.366PheArg: 2.366 ± 0.185
3.259PheSer: 3.259 ± 0.237
2.258PheThr: 2.258 ± 0.216
3.299PheVal: 3.299 ± 0.238
0.487PheTrp: 0.487 ± 0.072
1.163PheTyr: 1.163 ± 0.125
0.0PheXaa: 0.0 ± 0.0
Gly
5.071GlyAla: 5.071 ± 0.409
1.717GlyCys: 1.717 ± 0.172
4.313GlyAsp: 4.313 ± 0.294
3.691GlyGlu: 3.691 ± 0.236
2.123GlyPhe: 2.123 ± 0.209
5.814GlyGly: 5.814 ± 0.833
1.501GlyHis: 1.501 ± 0.16
3.232GlyIle: 3.232 ± 0.237
3.462GlyLys: 3.462 ± 0.226
4.989GlyLeu: 4.989 ± 0.29
1.46GlyMet: 1.46 ± 0.157
2.772GlyAsn: 2.772 ± 0.224
2.434GlyPro: 2.434 ± 0.634
1.487GlyGln: 1.487 ± 0.168
3.556GlyArg: 3.556 ± 0.225
5.49GlySer: 5.49 ± 0.318
4.408GlyThr: 4.408 ± 0.362
5.3GlyVal: 5.3 ± 0.329
0.541GlyTrp: 0.541 ± 0.082
1.907GlyTyr: 1.907 ± 0.187
0.0GlyXaa: 0.0 ± 0.0
His
1.961HisAla: 1.961 ± 0.146
0.419HisCys: 0.419 ± 0.093
1.569HisAsp: 1.569 ± 0.148
1.406HisGlu: 1.406 ± 0.137
1.19HisPhe: 1.19 ± 0.121
1.812HisGly: 1.812 ± 0.175
0.852HisHis: 0.852 ± 0.12
1.001HisIle: 1.001 ± 0.106
1.406HisLys: 1.406 ± 0.167
2.163HisLeu: 2.163 ± 0.163
0.608HisMet: 0.608 ± 0.089
0.825HisAsn: 0.825 ± 0.112
1.109HisPro: 1.109 ± 0.129
0.771HisGln: 0.771 ± 0.088
1.744HisArg: 1.744 ± 0.15
1.69HisSer: 1.69 ± 0.144
1.514HisThr: 1.514 ± 0.151
2.082HisVal: 2.082 ± 0.172
0.23HisTrp: 0.23 ± 0.063
0.527HisTyr: 0.527 ± 0.089
0.0HisXaa: 0.0 ± 0.0
Ile
3.38IleAla: 3.38 ± 0.206
1.055IleCys: 1.055 ± 0.122
3.61IleAsp: 3.61 ± 0.214
3.38IleGlu: 3.38 ± 0.243
1.866IlePhe: 1.866 ± 0.167
3.34IleGly: 3.34 ± 0.235
1.19IleHis: 1.19 ± 0.12
2.501IleIle: 2.501 ± 0.2
2.691IleLys: 2.691 ± 0.188
3.975IleLeu: 3.975 ± 0.236
1.487IleMet: 1.487 ± 0.144
2.245IleAsn: 2.245 ± 0.187
2.312IlePro: 2.312 ± 0.256
1.879IleGln: 1.879 ± 0.182
2.84IleArg: 2.84 ± 0.22
4.286IleSer: 4.286 ± 0.267
2.758IleThr: 2.758 ± 0.188
4.097IleVal: 4.097 ± 0.241
0.419IleTrp: 0.419 ± 0.084
1.325IleTyr: 1.325 ± 0.154
0.0IleXaa: 0.0 ± 0.0
Lys
4.259LysAla: 4.259 ± 0.465
0.825LysCys: 0.825 ± 0.105
3.11LysAsp: 3.11 ± 0.206
3.489LysGlu: 3.489 ± 0.311
1.961LysPhe: 1.961 ± 0.167
2.758LysGly: 2.758 ± 0.256
1.298LysHis: 1.298 ± 0.123
3.475LysIle: 3.475 ± 0.222
5.801LysLys: 5.801 ± 0.617
4.286LysLeu: 4.286 ± 0.271
1.839LysMet: 1.839 ± 0.177
3.029LysAsn: 3.029 ± 0.215
2.028LysPro: 2.028 ± 0.2
2.19LysGln: 2.19 ± 0.29
4.097LysArg: 4.097 ± 0.331
4.165LysSer: 4.165 ± 0.227
4.259LysThr: 4.259 ± 0.322
3.624LysVal: 3.624 ± 0.24
0.5LysTrp: 0.5 ± 0.101
1.893LysTyr: 1.893 ± 0.159
0.0LysXaa: 0.0 ± 0.0
Leu
5.801LeuAla: 5.801 ± 0.313
1.663LeuCys: 1.663 ± 0.167
4.638LeuAsp: 4.638 ± 0.255
5.287LeuGlu: 5.287 ± 0.379
3.935LeuPhe: 3.935 ± 0.264
4.678LeuGly: 4.678 ± 0.284
2.218LeuHis: 2.218 ± 0.217
3.015LeuIle: 3.015 ± 0.198
4.651LeuLys: 4.651 ± 0.316
7.788LeuLeu: 7.788 ± 0.452
2.312LeuMet: 2.312 ± 0.193
3.205LeuAsn: 3.205 ± 0.202
3.664LeuPro: 3.664 ± 0.286
3.164LeuGln: 3.164 ± 0.226
5.652LeuArg: 5.652 ± 0.316
6.369LeuSer: 6.369 ± 0.368
4.313LeuThr: 4.313 ± 0.276
6.193LeuVal: 6.193 ± 0.299
0.744LeuTrp: 0.744 ± 0.09
2.231LeuTyr: 2.231 ± 0.171
0.0LeuXaa: 0.0 ± 0.0
Met
1.961MetAla: 1.961 ± 0.182
0.622MetCys: 0.622 ± 0.089
1.677MetAsp: 1.677 ± 0.142
1.582MetGlu: 1.582 ± 0.15
1.258MetPhe: 1.258 ± 0.139
1.379MetGly: 1.379 ± 0.124
0.73MetHis: 0.73 ± 0.103
1.406MetIle: 1.406 ± 0.126
1.879MetLys: 1.879 ± 0.172
2.028MetLeu: 2.028 ± 0.177
0.852MetMet: 0.852 ± 0.119
1.406MetAsn: 1.406 ± 0.153
0.892MetPro: 0.892 ± 0.107
0.919MetGln: 0.919 ± 0.134
1.623MetArg: 1.623 ± 0.181
2.353MetSer: 2.353 ± 0.201
1.825MetThr: 1.825 ± 0.172
2.123MetVal: 2.123 ± 0.173
0.203MetTrp: 0.203 ± 0.056
1.068MetTyr: 1.068 ± 0.126
0.0MetXaa: 0.0 ± 0.0
Asn
3.34AsnAla: 3.34 ± 0.223
0.703AsnCys: 0.703 ± 0.089
2.677AsnAsp: 2.677 ± 0.216
2.001AsnGlu: 2.001 ± 0.2
1.582AsnPhe: 1.582 ± 0.136
2.921AsnGly: 2.921 ± 0.201
0.987AsnHis: 0.987 ± 0.122
2.596AsnIle: 2.596 ± 0.193
2.42AsnLys: 2.42 ± 0.22
3.624AsnLeu: 3.624 ± 0.23
1.339AsnMet: 1.339 ± 0.13
1.988AsnAsn: 1.988 ± 0.193
1.596AsnPro: 1.596 ± 0.173
1.122AsnGln: 1.122 ± 0.147
2.123AsnArg: 2.123 ± 0.183
2.799AsnSer: 2.799 ± 0.223
2.515AsnThr: 2.515 ± 0.199
3.083AsnVal: 3.083 ± 0.247
0.392AsnTrp: 0.392 ± 0.084
1.122AsnTyr: 1.122 ± 0.118
0.0AsnXaa: 0.0 ± 0.0
Pro
3.407ProAla: 3.407 ± 0.386
0.933ProCys: 0.933 ± 0.11
2.353ProAsp: 2.353 ± 0.212
2.096ProGlu: 2.096 ± 0.216
1.771ProPhe: 1.771 ± 0.164
2.785ProGly: 2.785 ± 0.205
0.798ProHis: 0.798 ± 0.124
1.609ProIle: 1.609 ± 0.138
1.663ProLys: 1.663 ± 0.182
3.489ProLeu: 3.489 ± 0.221
1.244ProMet: 1.244 ± 0.152
1.596ProAsn: 1.596 ± 0.146
2.664ProPro: 2.664 ± 0.395
1.203ProGln: 1.203 ± 0.189
2.38ProArg: 2.38 ± 0.179
3.921ProSer: 3.921 ± 0.249
2.501ProThr: 2.501 ± 0.208
3.218ProVal: 3.218 ± 0.23
0.433ProTrp: 0.433 ± 0.086
0.974ProTyr: 0.974 ± 0.097
0.0ProXaa: 0.0 ± 0.0
Gln
2.529GlnAla: 2.529 ± 0.2
0.595GlnCys: 0.595 ± 0.101
1.298GlnAsp: 1.298 ± 0.136
1.893GlnGlu: 1.893 ± 0.207
0.919GlnPhe: 0.919 ± 0.098
1.69GlnGly: 1.69 ± 0.166
0.933GlnHis: 0.933 ± 0.14
1.42GlnIle: 1.42 ± 0.14
2.163GlnLys: 2.163 ± 0.248
2.353GlnLeu: 2.353 ± 0.191
1.082GlnMet: 1.082 ± 0.125
1.42GlnAsn: 1.42 ± 0.163
1.379GlnPro: 1.379 ± 0.228
2.285GlnGln: 2.285 ± 0.492
2.474GlnArg: 2.474 ± 0.226
2.596GlnSer: 2.596 ± 0.207
2.015GlnThr: 2.015 ± 0.204
1.988GlnVal: 1.988 ± 0.185
0.5GlnTrp: 0.5 ± 0.097
0.906GlnTyr: 0.906 ± 0.131
0.0GlnXaa: 0.0 ± 0.0
Arg
4.435ArgAla: 4.435 ± 0.317
1.623ArgCys: 1.623 ± 0.161
3.543ArgAsp: 3.543 ± 0.223
3.962ArgGlu: 3.962 ± 0.286
2.096ArgPhe: 2.096 ± 0.166
4.124ArgGly: 4.124 ± 0.299
1.663ArgHis: 1.663 ± 0.151
3.123ArgIle: 3.123 ± 0.227
4.178ArgLys: 4.178 ± 0.323
5.219ArgLeu: 5.219 ± 0.27
1.514ArgMet: 1.514 ± 0.137
2.447ArgAsn: 2.447 ± 0.203
1.852ArgPro: 1.852 ± 0.175
2.069ArgGln: 2.069 ± 0.192
4.692ArgArg: 4.692 ± 0.293
4.273ArgSer: 4.273 ± 0.238
3.178ArgThr: 3.178 ± 0.264
5.044ArgVal: 5.044 ± 0.281
0.649ArgTrp: 0.649 ± 0.107
1.785ArgTyr: 1.785 ± 0.172
0.0ArgXaa: 0.0 ± 0.0
Ser
6.139SerAla: 6.139 ± 0.375
1.65SerCys: 1.65 ± 0.138
5.138SerAsp: 5.138 ± 0.338
4.543SerGlu: 4.543 ± 0.394
3.529SerPhe: 3.529 ± 0.229
5.882SerGly: 5.882 ± 0.373
1.758SerHis: 1.758 ± 0.169
4.543SerIle: 4.543 ± 0.254
3.908SerLys: 3.908 ± 0.287
6.152SerLeu: 6.152 ± 0.324
2.218SerMet: 2.218 ± 0.177
3.164SerAsn: 3.164 ± 0.23
3.205SerPro: 3.205 ± 0.254
1.961SerGln: 1.961 ± 0.14
4.949SerArg: 4.949 ± 0.302
8.492SerSer: 8.492 ± 0.575
5.287SerThr: 5.287 ± 0.352
6.301SerVal: 6.301 ± 0.317
0.771SerTrp: 0.771 ± 0.102
1.961SerTyr: 1.961 ± 0.201
0.0SerXaa: 0.0 ± 0.0
Thr
4.733ThrAla: 4.733 ± 0.301
1.217ThrCys: 1.217 ± 0.134
3.624ThrAsp: 3.624 ± 0.247
3.448ThrGlu: 3.448 ± 0.246
2.38ThrPhe: 2.38 ± 0.231
3.908ThrGly: 3.908 ± 0.287
1.555ThrHis: 1.555 ± 0.151
3.462ThrIle: 3.462 ± 0.179
3.462ThrLys: 3.462 ± 0.275
5.192ThrLeu: 5.192 ± 0.322
1.596ThrMet: 1.596 ± 0.161
2.312ThrAsn: 2.312 ± 0.151
3.462ThrPro: 3.462 ± 0.228
1.731ThrGln: 1.731 ± 0.159
3.353ThrArg: 3.353 ± 0.234
5.084ThrSer: 5.084 ± 0.321
4.624ThrThr: 4.624 ± 0.325
4.489ThrVal: 4.489 ± 0.24
0.636ThrTrp: 0.636 ± 0.086
1.731ThrTyr: 1.731 ± 0.184
0.0ThrXaa: 0.0 ± 0.0
Val
5.774ValAla: 5.774 ± 0.318
1.934ValCys: 1.934 ± 0.194
4.719ValAsp: 4.719 ± 0.284
4.381ValGlu: 4.381 ± 0.271
3.218ValPhe: 3.218 ± 0.204
4.76ValGly: 4.76 ± 0.328
2.231ValHis: 2.231 ± 0.187
3.434ValIle: 3.434 ± 0.247
3.637ValLys: 3.637 ± 0.233
6.139ValLeu: 6.139 ± 0.302
1.947ValMet: 1.947 ± 0.156
3.069ValAsn: 3.069 ± 0.247
2.718ValPro: 2.718 ± 0.251
2.691ValGln: 2.691 ± 0.183
4.53ValArg: 4.53 ± 0.254
6.517ValSer: 6.517 ± 0.28
4.232ValThr: 4.232 ± 0.287
6.179ValVal: 6.179 ± 0.342
0.608ValTrp: 0.608 ± 0.09
2.474ValTyr: 2.474 ± 0.188
0.0ValXaa: 0.0 ± 0.0
Trp
0.527TrpAla: 0.527 ± 0.076
0.149TrpCys: 0.149 ± 0.04
0.5TrpAsp: 0.5 ± 0.066
0.46TrpGlu: 0.46 ± 0.082
0.46TrpPhe: 0.46 ± 0.086
0.541TrpGly: 0.541 ± 0.09
0.27TrpHis: 0.27 ± 0.053
0.352TrpIle: 0.352 ± 0.066
0.771TrpLys: 0.771 ± 0.098
0.771TrpLeu: 0.771 ± 0.115
0.379TrpMet: 0.379 ± 0.073
0.5TrpAsn: 0.5 ± 0.086
0.352TrpPro: 0.352 ± 0.073
0.311TrpGln: 0.311 ± 0.062
0.771TrpArg: 0.771 ± 0.104
0.825TrpSer: 0.825 ± 0.097
0.649TrpThr: 0.649 ± 0.117
0.622TrpVal: 0.622 ± 0.086
0.149TrpTrp: 0.149 ± 0.048
0.365TrpTyr: 0.365 ± 0.07
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.109TyrAla: 2.109 ± 0.196
0.608TyrCys: 0.608 ± 0.103
2.015TyrAsp: 2.015 ± 0.165
1.474TyrGlu: 1.474 ± 0.127
1.312TyrPhe: 1.312 ± 0.134
1.65TyrGly: 1.65 ± 0.164
0.69TyrHis: 0.69 ± 0.097
1.69TyrIle: 1.69 ± 0.145
1.406TyrLys: 1.406 ± 0.132
2.204TyrLeu: 2.204 ± 0.188
0.838TyrMet: 0.838 ± 0.116
1.122TyrAsn: 1.122 ± 0.119
1.285TyrPro: 1.285 ± 0.136
0.865TyrGln: 0.865 ± 0.125
1.677TyrArg: 1.677 ± 0.139
2.082TyrSer: 2.082 ± 0.18
1.798TyrThr: 1.798 ± 0.164
2.136TyrVal: 2.136 ± 0.175
0.27TyrTrp: 0.27 ± 0.072
0.865TyrTyr: 0.865 ± 0.105
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 231 proteins (73957 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski