Trichophyton rubrum (strain ATCC MYA-4607 / CBS 118892) (Athlete s foot fungus)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Fungi; Dikarya; Ascomycota; saccharomyceta; Pezizomycotina; leotiomyceta; Eurotiomycetes; Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton; Trichophyton rubrum

Average proteome isoelectric point is 6.75

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 10006 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|F2SX70|F2SX70_TRIRC Uncharacterized protein OS=Trichophyton rubrum (strain ATCC MYA-4607 / CBS 118892) OX=559305 GN=TERG_07165 PE=4 SV=1
MM1 pKa = 7.73ADD3 pKa = 3.18SVSIYY8 pKa = 10.87DD9 pKa = 3.84EE10 pKa = 4.41IEE12 pKa = 4.35IEE14 pKa = 5.66DD15 pKa = 3.7MTFDD19 pKa = 3.82PVLQIYY25 pKa = 9.16HH26 pKa = 5.73YY27 pKa = 9.36PCPCGDD33 pKa = 3.29RR34 pKa = 11.84FEE36 pKa = 6.13IGLADD41 pKa = 3.99LRR43 pKa = 11.84DD44 pKa = 3.96GEE46 pKa = 5.15DD47 pKa = 2.8IGVCPSCSLMIRR59 pKa = 11.84VIFDD63 pKa = 3.33EE64 pKa = 5.08ADD66 pKa = 3.39LPKK69 pKa = 10.6DD70 pKa = 3.45DD71 pKa = 4.72SGNNGGVATAITAA84 pKa = 3.74

Molecular weight: 9.13 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|F2SBM8|F2SBM8_TRIRC Uncharacterized protein OS=Trichophyton rubrum (strain ATCC MYA-4607 / CBS 118892) OX=559305 GN=TERG_00488 PE=4 SV=1
MM1 pKa = 7.49LLSSQRR7 pKa = 11.84KK8 pKa = 7.76RR9 pKa = 11.84RR10 pKa = 11.84RR11 pKa = 11.84TTRR14 pKa = 11.84RR15 pKa = 11.84AALSLASVPASSEE28 pKa = 4.07TSSEE32 pKa = 3.61RR33 pKa = 11.84RR34 pKa = 11.84KK35 pKa = 9.5SKK37 pKa = 10.08KK38 pKa = 9.26RR39 pKa = 11.84RR40 pKa = 11.84RR41 pKa = 11.84TSKK44 pKa = 9.9RR45 pKa = 11.84RR46 pKa = 11.84KK47 pKa = 6.87TRR49 pKa = 11.84LRR51 pKa = 11.84KK52 pKa = 7.15TRR54 pKa = 11.84RR55 pKa = 11.84PRR57 pKa = 11.84RR58 pKa = 11.84MMLKK62 pKa = 10.46LLLLSSMLLRR72 pKa = 11.84SPSLPLPRR80 pKa = 11.84LLRR83 pKa = 11.84PLLLLLSQPLMLLLKK98 pKa = 9.78SQSPRR103 pKa = 11.84RR104 pKa = 11.84RR105 pKa = 11.84RR106 pKa = 11.84QRR108 pKa = 11.84LLSSLSVPPFLAPSSRR124 pKa = 11.84SSPRR128 pKa = 11.84KK129 pKa = 7.73TMTRR133 pKa = 11.84PRR135 pKa = 11.84RR136 pKa = 11.84RR137 pKa = 11.84SVLRR141 pKa = 11.84PQLSLAPLPSSATLSMLRR159 pKa = 11.84PPSQSSRR166 pKa = 11.84RR167 pKa = 11.84LLLLPMTMPLKK178 pKa = 10.31RR179 pKa = 11.84PRR181 pKa = 11.84RR182 pKa = 11.84PRR184 pKa = 11.84RR185 pKa = 11.84SLPQPRR191 pKa = 11.84ATSSSPSS198 pKa = 3.17

Molecular weight: 22.89 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

8617

1389

10006

4326730

42

7884

432.4

47.94

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

8.101 ± 0.022

1.268 ± 0.01

5.554 ± 0.017

6.245 ± 0.027

3.668 ± 0.016

6.621 ± 0.022

2.424 ± 0.011

5.175 ± 0.018

5.179 ± 0.023

8.853 ± 0.027

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.188 ± 0.009

3.829 ± 0.012

6.147 ± 0.031

4.123 ± 0.021

6.115 ± 0.023

8.705 ± 0.029

5.881 ± 0.019

5.87 ± 0.018

1.282 ± 0.009

2.771 ± 0.013
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski