Amino acid dipepetide frequency for Trichophyton rubrum (strain ATCC MYA-4607 / CBS 118892) (Athlete s foot fungus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.437AlaAla: 8.437 ± 0.057	0.981AlaCys: 0.981 ± 0.016	3.985AlaAsp: 3.985 ± 0.028	4.986AlaGlu: 4.986 ± 0.045	2.89AlaPhe: 2.89 ± 0.032	5.534AlaGly: 5.534 ± 0.037	1.684AlaHis: 1.684 ± 0.019	4.252AlaIle: 4.252 ± 0.032	4.059AlaLys: 4.059 ± 0.029	7.146AlaLeu: 7.146 ± 0.047	1.861AlaMet: 1.861 ± 0.021	2.879AlaAsn: 2.879 ± 0.025	4.442AlaPro: 4.442 ± 0.046	3.179AlaGln: 3.179 ± 0.031	4.688AlaArg: 4.688 ± 0.04	7.16AlaSer: 7.16 ± 0.052	4.871AlaThr: 4.871 ± 0.036	4.999AlaVal: 4.999 ± 0.036	0.983AlaTrp: 0.983 ± 0.015	1.991AlaTyr: 1.991 ± 0.023	0.0AlaXaa: 0.0 ± 0.0
Cys	0.887CysAla: 0.887 ± 0.015	0.289CysCys: 0.289 ± 0.009	0.609CysAsp: 0.609 ± 0.013	0.595CysGlu: 0.595 ± 0.013	0.562CysPhe: 0.562 ± 0.01	0.939CysGly: 0.939 ± 0.018	0.339CysHis: 0.339 ± 0.009	0.762CysIle: 0.762 ± 0.013	0.563CysLys: 0.563 ± 0.011	1.354CysLeu: 1.354 ± 0.02	0.315CysMet: 0.315 ± 0.008	0.428CysAsn: 0.428 ± 0.012	0.703CysPro: 0.703 ± 0.015	0.471CysGln: 0.471 ± 0.01	0.792CysArg: 0.792 ± 0.015	1.034CysSer: 1.034 ± 0.016	0.667CysThr: 0.667 ± 0.014	0.778CysVal: 0.778 ± 0.015	0.192CysTrp: 0.192 ± 0.007	0.398CysTyr: 0.398 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	4.234AspAla: 4.234 ± 0.033	0.653AspCys: 0.653 ± 0.014	4.033AspAsp: 4.033 ± 0.043	4.465AspGlu: 4.465 ± 0.041	2.068AspPhe: 2.068 ± 0.024	3.885AspGly: 3.885 ± 0.031	1.174AspHis: 1.174 ± 0.018	3.435AspIle: 3.435 ± 0.031	2.593AspLys: 2.593 ± 0.025	4.751AspLeu: 4.751 ± 0.036	1.274AspMet: 1.274 ± 0.017	1.994AspAsn: 1.994 ± 0.021	3.112AspPro: 3.112 ± 0.029	1.858AspGln: 1.858 ± 0.02	2.997AspArg: 2.997 ± 0.033	4.264AspSer: 4.264 ± 0.037	3.024AspThr: 3.024 ± 0.025	3.418AspVal: 3.418 ± 0.029	0.761AspTrp: 0.761 ± 0.013	1.547AspTyr: 1.547 ± 0.021	0.0AspXaa: 0.0 ± 0.0
Glu	5.176GluAla: 5.176 ± 0.041	0.658GluCys: 0.658 ± 0.015	4.177GluAsp: 4.177 ± 0.041	5.644GluGlu: 5.644 ± 0.059	1.991GluPhe: 1.991 ± 0.024	3.609GluGly: 3.609 ± 0.034	1.366GluHis: 1.366 ± 0.018	3.229GluIle: 3.229 ± 0.03	4.127GluLys: 4.127 ± 0.037	5.243GluLeu: 5.243 ± 0.04	1.452GluMet: 1.452 ± 0.018	2.497GluAsn: 2.497 ± 0.026	2.859GluPro: 2.859 ± 0.037	2.504GluGln: 2.504 ± 0.028	3.904GluArg: 3.904 ± 0.038	4.51GluSer: 4.51 ± 0.033	3.453GluThr: 3.453 ± 0.031	3.472GluVal: 3.472 ± 0.028	0.794GluTrp: 0.794 ± 0.014	1.788GluTyr: 1.788 ± 0.024	0.0GluXaa: 0.0 ± 0.0
Phe	2.786PheAla: 2.786 ± 0.027	0.581PheCys: 0.581 ± 0.012	2.237PheAsp: 2.237 ± 0.025	2.078PheGlu: 2.078 ± 0.023	1.596PhePhe: 1.596 ± 0.023	2.63PheGly: 2.63 ± 0.03	0.922PheHis: 0.922 ± 0.016	1.925PheIle: 1.925 ± 0.026	1.628PheLys: 1.628 ± 0.017	3.425PheLeu: 3.425 ± 0.036	0.777PheMet: 0.777 ± 0.013	1.491PheAsn: 1.491 ± 0.017	1.979PhePro: 1.979 ± 0.02	1.358PheGln: 1.358 ± 0.018	1.992PheArg: 1.992 ± 0.022	3.229PheSer: 3.229 ± 0.029	2.167PheThr: 2.167 ± 0.023	2.26PheVal: 2.26 ± 0.023	0.546PheTrp: 0.546 ± 0.012	1.077PheTyr: 1.077 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	4.738GlyAla: 4.738 ± 0.035	0.892GlyCys: 0.892 ± 0.017	3.506GlyAsp: 3.506 ± 0.034	3.705GlyGlu: 3.705 ± 0.036	2.58GlyPhe: 2.58 ± 0.026	5.453GlyGly: 5.453 ± 0.051	1.629GlyHis: 1.629 ± 0.021	3.599GlyIle: 3.599 ± 0.03	3.625GlyLys: 3.625 ± 0.034	5.645GlyLeu: 5.645 ± 0.037	1.598GlyMet: 1.598 ± 0.02	2.556GlyAsn: 2.556 ± 0.029	3.222GlyPro: 3.222 ± 0.034	2.562GlyGln: 2.562 ± 0.028	4.044GlyArg: 4.044 ± 0.034	5.767GlySer: 5.767 ± 0.04	3.822GlyThr: 3.822 ± 0.031	4.152GlyVal: 4.152 ± 0.033	1.026GlyTrp: 1.026 ± 0.017	2.09GlyTyr: 2.09 ± 0.023	0.0GlyXaa: 0.0 ± 0.0
His	1.705HisAla: 1.705 ± 0.019	0.322HisCys: 0.322 ± 0.009	1.294HisAsp: 1.294 ± 0.019	1.289HisGlu: 1.289 ± 0.02	0.912HisPhe: 0.912 ± 0.015	1.709HisGly: 1.709 ± 0.025	0.966HisHis: 0.966 ± 0.021	1.352HisIle: 1.352 ± 0.017	0.914HisLys: 0.914 ± 0.015	2.241HisLeu: 2.241 ± 0.025	0.49HisMet: 0.49 ± 0.011	0.881HisAsn: 0.881 ± 0.016	1.75HisPro: 1.75 ± 0.019	1.14HisGln: 1.14 ± 0.022	1.613HisArg: 1.613 ± 0.02	2.078HisSer: 2.078 ± 0.024	1.304HisThr: 1.304 ± 0.016	1.313HisVal: 1.313 ± 0.017	0.293HisTrp: 0.293 ± 0.008	0.676HisTyr: 0.676 ± 0.014	0.0HisXaa: 0.0 ± 0.0
Ile	3.986IleAla: 3.986 ± 0.035	0.823IleCys: 0.823 ± 0.016	3.03IleAsp: 3.03 ± 0.027	3.072IleGlu: 3.072 ± 0.029	2.106IlePhe: 2.106 ± 0.024	3.173IleGly: 3.173 ± 0.032	1.303IleHis: 1.303 ± 0.019	2.726IleIle: 2.726 ± 0.03	2.493IleLys: 2.493 ± 0.028	4.817IleLeu: 4.817 ± 0.039	1.089IleMet: 1.089 ± 0.017	1.951IleAsn: 1.951 ± 0.023	3.387IlePro: 3.387 ± 0.029	2.048IleGln: 2.048 ± 0.024	3.029IleArg: 3.029 ± 0.029	4.451IleSer: 4.451 ± 0.035	2.958IleThr: 2.958 ± 0.029	3.11IleVal: 3.11 ± 0.028	0.684IleTrp: 0.684 ± 0.012	1.515IleTyr: 1.515 ± 0.019	0.0IleXaa: 0.0 ± 0.0
Lys	4.353LysAla: 4.353 ± 0.036	0.571LysCys: 0.571 ± 0.014	2.966LysAsp: 2.966 ± 0.028	3.772LysGlu: 3.772 ± 0.033	1.593LysPhe: 1.593 ± 0.023	3.156LysGly: 3.156 ± 0.033	1.154LysHis: 1.154 ± 0.017	2.529LysIle: 2.529 ± 0.025	3.74LysLys: 3.74 ± 0.049	4.428LysLeu: 4.428 ± 0.034	1.108LysMet: 1.108 ± 0.014	1.912LysAsn: 1.912 ± 0.021	3.083LysPro: 3.083 ± 0.031	2.059LysGln: 2.059 ± 0.024	3.587LysArg: 3.587 ± 0.032	3.89LysSer: 3.89 ± 0.036	2.833LysThr: 2.833 ± 0.024	2.889LysVal: 2.889 ± 0.028	0.636LysTrp: 0.636 ± 0.014	1.534LysTyr: 1.534 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	7.353LeuAla: 7.353 ± 0.045	1.234LeuCys: 1.234 ± 0.018	5.053LeuAsp: 5.053 ± 0.037	5.501LeuGlu: 5.501 ± 0.039	3.395LeuPhe: 3.395 ± 0.031	5.56LeuGly: 5.56 ± 0.039	2.189LeuHis: 2.189 ± 0.025	4.112LeuIle: 4.112 ± 0.033	4.497LeuLys: 4.497 ± 0.033	8.428LeuLeu: 8.428 ± 0.057	1.731LeuMet: 1.731 ± 0.022	3.349LeuAsn: 3.349 ± 0.029	5.543LeuPro: 5.543 ± 0.044	3.756LeuGln: 3.756 ± 0.036	5.731LeuArg: 5.731 ± 0.041	7.648LeuSer: 7.648 ± 0.051	4.827LeuThr: 4.827 ± 0.039	5.167LeuVal: 5.167 ± 0.045	1.102LeuTrp: 1.102 ± 0.017	2.351LeuTyr: 2.351 ± 0.023	0.0LeuXaa: 0.0 ± 0.0
Met	2.202MetAla: 2.202 ± 0.025	0.231MetCys: 0.231 ± 0.007	1.258MetAsp: 1.258 ± 0.019	1.366MetGlu: 1.366 ± 0.019	0.783MetPhe: 0.783 ± 0.013	1.494MetGly: 1.494 ± 0.02	0.504MetHis: 0.504 ± 0.011	1.067MetIle: 1.067 ± 0.018	1.171MetLys: 1.171 ± 0.019	1.944MetLeu: 1.944 ± 0.022	0.57MetMet: 0.57 ± 0.013	0.861MetAsn: 0.861 ± 0.016	1.201MetPro: 1.201 ± 0.017	0.875MetGln: 0.875 ± 0.018	1.181MetArg: 1.181 ± 0.017	1.787MetSer: 1.787 ± 0.019	1.246MetThr: 1.246 ± 0.016	1.378MetVal: 1.378 ± 0.021	0.234MetTrp: 0.234 ± 0.007	0.526MetTyr: 0.526 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	2.971AsnAla: 2.971 ± 0.029	0.47AsnCys: 0.47 ± 0.011	2.03AsnAsp: 2.03 ± 0.022	2.198AsnGlu: 2.198 ± 0.024	1.402AsnPhe: 1.402 ± 0.02	2.99AsnGly: 2.99 ± 0.03	0.892AsnHis: 0.892 ± 0.015	2.349AsnIle: 2.349 ± 0.024	1.747AsnLys: 1.747 ± 0.021	3.329AsnLeu: 3.329 ± 0.031	0.903AsnMet: 0.903 ± 0.014	1.772AsnAsn: 1.772 ± 0.03	2.537AsnPro: 2.537 ± 0.026	1.458AsnGln: 1.458 ± 0.021	2.066AsnArg: 2.066 ± 0.026	3.051AsnSer: 3.051 ± 0.027	2.327AsnThr: 2.327 ± 0.024	2.251AsnVal: 2.251 ± 0.025	0.502AsnTrp: 0.502 ± 0.011	1.05AsnTyr: 1.05 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	5.193ProAla: 5.193 ± 0.049	0.581ProCys: 0.581 ± 0.014	3.146ProAsp: 3.146 ± 0.03	3.875ProGlu: 3.875 ± 0.033	2.084ProPhe: 2.084 ± 0.022	3.926ProGly: 3.926 ± 0.038	1.4ProHis: 1.4 ± 0.02	2.671ProIle: 2.671 ± 0.028	2.839ProLys: 2.839 ± 0.029	4.785ProLeu: 4.785 ± 0.034	1.114ProMet: 1.114 ± 0.016	2.272ProAsn: 2.272 ± 0.027	5.439ProPro: 5.439 ± 0.077	2.615ProGln: 2.615 ± 0.03	3.4ProArg: 3.4 ± 0.035	6.346ProSer: 6.346 ± 0.053	4.009ProThr: 4.009 ± 0.045	3.575ProVal: 3.575 ± 0.033	0.654ProTrp: 0.654 ± 0.013	1.548ProTyr: 1.548 ± 0.02	0.0ProXaa: 0.0 ± 0.0
Gln	3.318GlnAla: 3.318 ± 0.036	0.429GlnCys: 0.429 ± 0.01	1.963GlnAsp: 1.963 ± 0.022	2.438GlnGlu: 2.438 ± 0.026	1.316GlnPhe: 1.316 ± 0.02	2.355GlnGly: 2.355 ± 0.026	1.245GlnHis: 1.245 ± 0.021	1.916GlnIle: 1.916 ± 0.022	2.135GlnLys: 2.135 ± 0.022	3.559GlnLeu: 3.559 ± 0.033	0.896GlnMet: 0.896 ± 0.017	1.6GlnAsn: 1.6 ± 0.02	2.864GlnPro: 2.864 ± 0.041	3.207GlnGln: 3.207 ± 0.086	2.706GlnArg: 2.706 ± 0.026	3.256GlnSer: 3.256 ± 0.031	2.233GlnThr: 2.233 ± 0.027	2.128GlnVal: 2.128 ± 0.023	0.481GlnTrp: 0.481 ± 0.01	1.186GlnTyr: 1.186 ± 0.018	0.0GlnXaa: 0.0 ± 0.0
Arg	4.525ArgAla: 4.525 ± 0.033	0.775ArgCys: 0.775 ± 0.016	3.362ArgAsp: 3.362 ± 0.037	3.981ArgGlu: 3.981 ± 0.041	2.113ArgPhe: 2.113 ± 0.022	3.701ArgGly: 3.701 ± 0.034	1.604ArgHis: 1.604 ± 0.018	3.024ArgIle: 3.024 ± 0.029	3.542ArgLys: 3.542 ± 0.031	5.402ArgLeu: 5.402 ± 0.038	1.358ArgMet: 1.358 ± 0.018	2.343ArgAsn: 2.343 ± 0.024	3.492ArgPro: 3.492 ± 0.034	2.677ArgGln: 2.677 ± 0.03	5.114ArgArg: 5.114 ± 0.053	5.042ArgSer: 5.042 ± 0.044	3.193ArgThr: 3.193 ± 0.03	3.325ArgVal: 3.325 ± 0.028	0.838ArgTrp: 0.838 ± 0.013	1.741ArgTyr: 1.741 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	6.485SerAla: 6.485 ± 0.042	0.972SerCys: 0.972 ± 0.016	4.098SerAsp: 4.098 ± 0.035	4.263SerGlu: 4.263 ± 0.034	3.142SerPhe: 3.142 ± 0.031	5.67SerGly: 5.67 ± 0.04	2.145SerHis: 2.145 ± 0.027	4.381SerIle: 4.381 ± 0.035	4.325SerLys: 4.325 ± 0.037	7.682SerLeu: 7.682 ± 0.043	1.894SerMet: 1.894 ± 0.02	3.438SerAsn: 3.438 ± 0.031	5.826SerPro: 5.826 ± 0.058	3.555SerGln: 3.555 ± 0.035	5.486SerArg: 5.486 ± 0.046	9.937SerSer: 9.937 ± 0.084	5.958SerThr: 5.958 ± 0.047	4.602SerVal: 4.602 ± 0.035	1.031SerTrp: 1.031 ± 0.015	2.161SerTyr: 2.161 ± 0.021	0.0SerXaa: 0.0 ± 0.0
Thr	5.046ThrAla: 5.046 ± 0.039	0.757ThrCys: 0.757 ± 0.016	2.783ThrAsp: 2.783 ± 0.03	3.116ThrGlu: 3.116 ± 0.029	2.124ThrPhe: 2.124 ± 0.025	4.037ThrGly: 4.037 ± 0.029	1.31ThrHis: 1.31 ± 0.02	3.107ThrIle: 3.107 ± 0.029	2.739ThrLys: 2.739 ± 0.029	5.166ThrLeu: 5.166 ± 0.035	1.194ThrMet: 1.194 ± 0.016	2.172ThrAsn: 2.172 ± 0.023	4.464ThrPro: 4.464 ± 0.036	2.073ThrGln: 2.073 ± 0.025	3.048ThrArg: 3.048 ± 0.028	5.621ThrSer: 5.621 ± 0.051	4.21ThrThr: 4.21 ± 0.053	3.59ThrVal: 3.59 ± 0.033	0.71ThrTrp: 0.71 ± 0.013	1.539ThrTyr: 1.539 ± 0.019	0.0ThrXaa: 0.0 ± 0.0
Val	4.691ValAla: 4.691 ± 0.035	0.862ValCys: 0.862 ± 0.015	3.632ValAsp: 3.632 ± 0.03	3.804ValGlu: 3.804 ± 0.031	2.338ValPhe: 2.338 ± 0.026	3.674ValGly: 3.674 ± 0.039	1.326ValHis: 1.326 ± 0.018	3.053ValIle: 3.053 ± 0.031	3.062ValLys: 3.062 ± 0.033	5.292ValLeu: 5.292 ± 0.042	1.31ValMet: 1.31 ± 0.02	2.205ValAsn: 2.205 ± 0.022	3.447ValPro: 3.447 ± 0.031	2.193ValGln: 2.193 ± 0.024	3.27ValArg: 3.27 ± 0.027	4.793ValSer: 4.793 ± 0.032	3.35ValThr: 3.35 ± 0.032	3.972ValVal: 3.972 ± 0.037	0.738ValTrp: 0.738 ± 0.014	1.688ValTyr: 1.688 ± 0.021	0.0ValXaa: 0.0 ± 0.0
Trp	0.946TrpAla: 0.946 ± 0.016	0.169TrpCys: 0.169 ± 0.006	0.788TrpAsp: 0.788 ± 0.015	0.776TrpGlu: 0.776 ± 0.013	0.465TrpPhe: 0.465 ± 0.011	0.769TrpGly: 0.769 ± 0.015	0.303TrpHis: 0.303 ± 0.009	0.708TrpIle: 0.708 ± 0.013	0.795TrpLys: 0.795 ± 0.013	1.206TrpLeu: 1.206 ± 0.016	0.332TrpMet: 0.332 ± 0.009	0.595TrpAsn: 0.595 ± 0.01	0.531TrpPro: 0.531 ± 0.011	0.483TrpGln: 0.483 ± 0.01	0.863TrpArg: 0.863 ± 0.014	0.985TrpSer: 0.985 ± 0.017	0.757TrpThr: 0.757 ± 0.012	0.74TrpVal: 0.74 ± 0.013	0.231TrpTrp: 0.231 ± 0.009	0.381TrpTyr: 0.381 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.975TyrAla: 1.975 ± 0.02	0.428TyrCys: 0.428 ± 0.01	1.589TyrAsp: 1.589 ± 0.023	1.527TyrGlu: 1.527 ± 0.02	1.224TyrPhe: 1.224 ± 0.018	1.945TyrGly: 1.945 ± 0.026	0.787TyrHis: 0.787 ± 0.014	1.554TyrIle: 1.554 ± 0.02	1.196TyrLys: 1.196 ± 0.018	2.684TyrLeu: 2.684 ± 0.029	0.612TyrMet: 0.612 ± 0.011	1.1TyrAsn: 1.1 ± 0.015	1.591TyrPro: 1.591 ± 0.02	1.159TyrGln: 1.159 ± 0.018	1.641TyrArg: 1.641 ± 0.019	2.202TyrSer: 2.202 ± 0.026	1.6TyrThr: 1.6 ± 0.02	1.581TyrVal: 1.581 ± 0.021	0.389TyrTrp: 0.389 ± 0.009	0.924TyrTyr: 0.924 ± 0.016	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 10006 proteins (4326730 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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