Amino acid dipepetide frequency for Paraglaciecola psychrophila 170

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.999AlaAla: 6.999 ± 0.092	0.886AlaCys: 0.886 ± 0.025	4.618AlaAsp: 4.618 ± 0.059	4.76AlaGlu: 4.76 ± 0.056	3.431AlaPhe: 3.431 ± 0.054	5.589AlaGly: 5.589 ± 0.074	1.541AlaHis: 1.541 ± 0.038	5.846AlaIle: 5.846 ± 0.073	4.949AlaLys: 4.949 ± 0.071	8.812AlaLeu: 8.812 ± 0.089	2.313AlaMet: 2.313 ± 0.045	3.858AlaAsn: 3.858 ± 0.051	2.549AlaPro: 2.549 ± 0.04	3.566AlaGln: 3.566 ± 0.051	3.067AlaArg: 3.067 ± 0.045	5.369AlaSer: 5.369 ± 0.071	4.315AlaThr: 4.315 ± 0.058	5.306AlaVal: 5.306 ± 0.065	0.855AlaTrp: 0.855 ± 0.026	2.452AlaTyr: 2.452 ± 0.045	0.0AlaXaa: 0.0 ± 0.0
Cys	0.786CysAla: 0.786 ± 0.02	0.176CysCys: 0.176 ± 0.01	0.575CysAsp: 0.575 ± 0.021	0.577CysGlu: 0.577 ± 0.016	0.497CysPhe: 0.497 ± 0.017	0.78CysGly: 0.78 ± 0.026	0.322CysHis: 0.322 ± 0.014	0.722CysIle: 0.722 ± 0.022	0.501CysLys: 0.501 ± 0.021	1.128CysLeu: 1.128 ± 0.028	0.263CysMet: 0.263 ± 0.012	0.357CysAsn: 0.357 ± 0.016	0.418CysPro: 0.418 ± 0.02	0.47CysGln: 0.47 ± 0.017	0.399CysArg: 0.399 ± 0.015	0.727CysSer: 0.727 ± 0.024	0.464CysThr: 0.464 ± 0.017	0.624CysVal: 0.624 ± 0.02	0.131CysTrp: 0.131 ± 0.01	0.347CysTyr: 0.347 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	4.376AspAla: 4.376 ± 0.064	0.528AspCys: 0.528 ± 0.022	3.192AspAsp: 3.192 ± 0.067	3.578AspGlu: 3.578 ± 0.066	2.762AspPhe: 2.762 ± 0.043	3.711AspGly: 3.711 ± 0.079	0.992AspHis: 0.992 ± 0.025	4.447AspIle: 4.447 ± 0.06	3.592AspLys: 3.592 ± 0.053	5.316AspLeu: 5.316 ± 0.066	1.498AspMet: 1.498 ± 0.033	2.837AspAsn: 2.837 ± 0.047	2.026AspPro: 2.026 ± 0.047	1.905AspGln: 1.905 ± 0.034	1.966AspArg: 1.966 ± 0.036	3.382AspSer: 3.382 ± 0.056	3.016AspThr: 3.016 ± 0.058	3.92AspVal: 3.92 ± 0.055	0.902AspTrp: 0.902 ± 0.025	2.137AspTyr: 2.137 ± 0.038	0.0AspXaa: 0.0 ± 0.0
Glu	4.255GluAla: 4.255 ± 0.052	0.461GluCys: 0.461 ± 0.019	2.763GluAsp: 2.763 ± 0.042	2.986GluGlu: 2.986 ± 0.062	2.58GluPhe: 2.58 ± 0.041	3.128GluGly: 3.128 ± 0.049	1.556GluHis: 1.556 ± 0.034	3.749GluIle: 3.749 ± 0.052	3.64GluLys: 3.64 ± 0.048	6.59GluLeu: 6.59 ± 0.079	1.483GluMet: 1.483 ± 0.029	2.851GluAsn: 2.851 ± 0.049	1.815GluPro: 1.815 ± 0.042	3.859GluGln: 3.859 ± 0.068	2.602GluArg: 2.602 ± 0.048	3.496GluSer: 3.496 ± 0.051	2.936GluThr: 2.936 ± 0.048	3.825GluVal: 3.825 ± 0.058	0.67GluTrp: 0.67 ± 0.021	1.861GluTyr: 1.861 ± 0.038	0.0GluXaa: 0.0 ± 0.0
Phe	3.646PheAla: 3.646 ± 0.054	0.575PheCys: 0.575 ± 0.022	2.913PheAsp: 2.913 ± 0.048	2.726PheGlu: 2.726 ± 0.037	1.905PhePhe: 1.905 ± 0.041	3.266PheGly: 3.266 ± 0.055	0.805PheHis: 0.805 ± 0.023	3.116PheIle: 3.116 ± 0.056	2.257PheLys: 2.257 ± 0.041	3.624PheLeu: 3.624 ± 0.06	1.189PheMet: 1.189 ± 0.027	2.339PheAsn: 2.339 ± 0.041	1.484PhePro: 1.484 ± 0.035	1.254PheGln: 1.254 ± 0.027	1.542PheArg: 1.542 ± 0.035	3.804PheSer: 3.804 ± 0.052	2.541PheThr: 2.541 ± 0.05	2.927PheVal: 2.927 ± 0.045	0.566PheTrp: 0.566 ± 0.019	1.526PheTyr: 1.526 ± 0.034	0.0PheXaa: 0.0 ± 0.0
Gly	4.933GlyAla: 4.933 ± 0.072	0.817GlyCys: 0.817 ± 0.027	3.65GlyAsp: 3.65 ± 0.071	3.799GlyGlu: 3.799 ± 0.056	3.443GlyPhe: 3.443 ± 0.053	4.637GlyGly: 4.637 ± 0.067	1.472GlyHis: 1.472 ± 0.029	4.798GlyIle: 4.798 ± 0.062	3.964GlyLys: 3.964 ± 0.055	7.088GlyLeu: 7.088 ± 0.068	1.841GlyMet: 1.841 ± 0.038	2.831GlyAsn: 2.831 ± 0.054	1.67GlyPro: 1.67 ± 0.041	2.795GlyGln: 2.795 ± 0.04	2.716GlyArg: 2.716 ± 0.05	4.236GlySer: 4.236 ± 0.066	3.384GlyThr: 3.384 ± 0.057	4.779GlyVal: 4.779 ± 0.067	0.938GlyTrp: 0.938 ± 0.025	2.531GlyTyr: 2.531 ± 0.041	0.0GlyXaa: 0.0 ± 0.0
His	1.56HisAla: 1.56 ± 0.036	0.324HisCys: 0.324 ± 0.016	1.057HisAsp: 1.057 ± 0.029	1.06HisGlu: 1.06 ± 0.028	1.113HisPhe: 1.113 ± 0.029	1.393HisGly: 1.393 ± 0.037	0.711HisHis: 0.711 ± 0.026	1.556HisIle: 1.556 ± 0.037	1.203HisLys: 1.203 ± 0.028	2.187HisLeu: 2.187 ± 0.043	0.545HisMet: 0.545 ± 0.02	0.995HisAsn: 0.995 ± 0.031	1.072HisPro: 1.072 ± 0.028	1.176HisGln: 1.176 ± 0.032	0.989HisArg: 0.989 ± 0.025	1.529HisSer: 1.529 ± 0.031	1.157HisThr: 1.157 ± 0.027	1.248HisVal: 1.248 ± 0.029	0.327HisTrp: 0.327 ± 0.016	0.873HisTyr: 0.873 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	6.208IleAla: 6.208 ± 0.066	0.775IleCys: 0.775 ± 0.021	4.617IleAsp: 4.617 ± 0.061	4.71IleGlu: 4.71 ± 0.058	2.672IlePhe: 2.672 ± 0.049	4.847IleGly: 4.847 ± 0.059	1.351IleHis: 1.351 ± 0.032	4.322IleIle: 4.322 ± 0.059	3.999IleLys: 3.999 ± 0.052	5.81IleLeu: 5.81 ± 0.068	1.512IleMet: 1.512 ± 0.034	3.699IleAsn: 3.699 ± 0.055	2.691IlePro: 2.691 ± 0.043	2.702IleGln: 2.702 ± 0.045	2.773IleArg: 2.773 ± 0.044	5.233IleSer: 5.233 ± 0.063	3.962IleThr: 3.962 ± 0.055	4.292IleVal: 4.292 ± 0.062	0.719IleTrp: 0.719 ± 0.022	1.891IleTyr: 1.891 ± 0.038	0.0IleXaa: 0.0 ± 0.0
Lys	4.563LysAla: 4.563 ± 0.068	0.393LysCys: 0.393 ± 0.018	2.85LysAsp: 2.85 ± 0.044	3.023LysGlu: 3.023 ± 0.048	1.895LysPhe: 1.895 ± 0.036	3.429LysGly: 3.429 ± 0.059	1.418LysHis: 1.418 ± 0.034	3.7LysIle: 3.7 ± 0.046	3.272LysLys: 3.272 ± 0.054	5.727LysLeu: 5.727 ± 0.07	1.531LysMet: 1.531 ± 0.034	2.821LysAsn: 2.821 ± 0.048	2.325LysPro: 2.325 ± 0.041	3.353LysGln: 3.353 ± 0.053	2.754LysArg: 2.754 ± 0.049	3.564LysSer: 3.564 ± 0.056	3.462LysThr: 3.462 ± 0.043	3.952LysVal: 3.952 ± 0.055	0.653LysTrp: 0.653 ± 0.019	1.606LysTyr: 1.606 ± 0.037	0.0LysXaa: 0.0 ± 0.0
Leu	9.215LeuAla: 9.215 ± 0.089	1.109LeuCys: 1.109 ± 0.028	5.785LeuAsp: 5.785 ± 0.07	5.576LeuGlu: 5.576 ± 0.064	4.371LeuPhe: 4.371 ± 0.058	6.942LeuGly: 6.942 ± 0.084	2.072LeuHis: 2.072 ± 0.04	6.814LeuIle: 6.814 ± 0.077	5.706LeuLys: 5.706 ± 0.059	10.555LeuLeu: 10.555 ± 0.109	2.68LeuMet: 2.68 ± 0.045	5.114LeuAsn: 5.114 ± 0.061	4.463LeuPro: 4.463 ± 0.056	4.134LeuGln: 4.134 ± 0.065	3.993LeuArg: 3.993 ± 0.048	8.212LeuSer: 8.212 ± 0.079	6.045LeuThr: 6.045 ± 0.061	6.902LeuVal: 6.902 ± 0.074	1.012LeuTrp: 1.012 ± 0.028	2.74LeuTyr: 2.74 ± 0.044	0.0LeuXaa: 0.0 ± 0.0
Met	2.355MetAla: 2.355 ± 0.042	0.249MetCys: 0.249 ± 0.013	1.178MetAsp: 1.178 ± 0.03	1.045MetGlu: 1.045 ± 0.024	1.057MetPhe: 1.057 ± 0.031	1.765MetGly: 1.765 ± 0.038	0.526MetHis: 0.526 ± 0.021	1.435MetIle: 1.435 ± 0.031	1.365MetLys: 1.365 ± 0.029	3.008MetLeu: 3.008 ± 0.057	0.692MetMet: 0.692 ± 0.022	1.121MetAsn: 1.121 ± 0.029	1.308MetPro: 1.308 ± 0.033	1.465MetGln: 1.465 ± 0.032	1.147MetArg: 1.147 ± 0.03	1.99MetSer: 1.99 ± 0.036	1.554MetThr: 1.554 ± 0.031	1.606MetVal: 1.606 ± 0.031	0.245MetTrp: 0.245 ± 0.013	0.57MetTyr: 0.57 ± 0.021	0.0MetXaa: 0.0 ± 0.0
Asn	3.556AsnAla: 3.556 ± 0.051	0.452AsnCys: 0.452 ± 0.02	2.481AsnAsp: 2.481 ± 0.046	2.529AsnGlu: 2.529 ± 0.043	1.898AsnPhe: 1.898 ± 0.04	3.074AsnGly: 3.074 ± 0.051	1.051AsnHis: 1.051 ± 0.028	3.749AsnIle: 3.749 ± 0.056	2.921AsnLys: 2.921 ± 0.047	4.586AsnLeu: 4.586 ± 0.061	1.224AsnMet: 1.224 ± 0.027	2.535AsnAsn: 2.535 ± 0.053	2.021AsnPro: 2.021 ± 0.036	2.454AsnGln: 2.454 ± 0.051	1.953AsnArg: 1.953 ± 0.035	3.068AsnSer: 3.068 ± 0.055	2.723AsnThr: 2.723 ± 0.051	3.003AsnVal: 3.003 ± 0.038	0.754AsnTrp: 0.754 ± 0.025	1.563AsnTyr: 1.563 ± 0.033	0.0AsnXaa: 0.0 ± 0.0
Pro	2.722ProAla: 2.722 ± 0.052	0.303ProCys: 0.303 ± 0.015	2.363ProAsp: 2.363 ± 0.038	2.833ProGlu: 2.833 ± 0.041	1.739ProPhe: 1.739 ± 0.033	2.178ProGly: 2.178 ± 0.045	0.758ProHis: 0.758 ± 0.023	2.787ProIle: 2.787 ± 0.04	2.188ProLys: 2.188 ± 0.036	3.749ProLeu: 3.749 ± 0.054	0.97ProMet: 0.97 ± 0.026	1.916ProAsn: 1.916 ± 0.043	1.118ProPro: 1.118 ± 0.029	1.642ProGln: 1.642 ± 0.03	1.285ProArg: 1.285 ± 0.031	2.543ProSer: 2.543 ± 0.045	1.989ProThr: 1.989 ± 0.045	2.736ProVal: 2.736 ± 0.047	0.482ProTrp: 0.482 ± 0.018	1.195ProTyr: 1.195 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	4.244GlnAla: 4.244 ± 0.057	0.388GlnCys: 0.388 ± 0.015	2.249GlnAsp: 2.249 ± 0.036	2.209GlnGlu: 2.209 ± 0.042	1.893GlnPhe: 1.893 ± 0.037	2.953GlnGly: 2.953 ± 0.047	1.339GlnHis: 1.339 ± 0.032	3.059GlnIle: 3.059 ± 0.043	2.481GlnLys: 2.481 ± 0.041	5.157GlnLeu: 5.157 ± 0.078	1.072GlnMet: 1.072 ± 0.024	2.035GlnAsn: 2.035 ± 0.045	1.721GlnPro: 1.721 ± 0.034	3.648GlnGln: 3.648 ± 0.085	2.239GlnArg: 2.239 ± 0.046	3.152GlnSer: 3.152 ± 0.052	2.562GlnThr: 2.562 ± 0.045	3.108GlnVal: 3.108 ± 0.043	0.668GlnTrp: 0.668 ± 0.023	1.429GlnTyr: 1.429 ± 0.034	0.0GlnXaa: 0.0 ± 0.0
Arg	3.053ArgAla: 3.053 ± 0.045	0.396ArgCys: 0.396 ± 0.017	2.184ArgAsp: 2.184 ± 0.04	2.371ArgGlu: 2.371 ± 0.044	2.095ArgPhe: 2.095 ± 0.037	2.477ArgGly: 2.477 ± 0.046	0.957ArgHis: 0.957 ± 0.024	2.798ArgIle: 2.798 ± 0.046	2.297ArgLys: 2.297 ± 0.042	4.65ArgLeu: 4.65 ± 0.06	1.101ArgMet: 1.101 ± 0.025	1.81ArgAsn: 1.81 ± 0.035	1.491ArgPro: 1.491 ± 0.031	2.065ArgGln: 2.065 ± 0.035	1.93ArgArg: 1.93 ± 0.037	2.481ArgSer: 2.481 ± 0.043	1.955ArgThr: 1.955 ± 0.039	2.819ArgVal: 2.819 ± 0.05	0.585ArgTrp: 0.585 ± 0.019	1.587ArgTyr: 1.587 ± 0.031	0.0ArgXaa: 0.0 ± 0.0
Ser	5.479SerAla: 5.479 ± 0.063	0.717SerCys: 0.717 ± 0.022	3.95SerAsp: 3.95 ± 0.072	4.079SerGlu: 4.079 ± 0.056	3.07SerPhe: 3.07 ± 0.05	5.023SerGly: 5.023 ± 0.075	1.592SerHis: 1.592 ± 0.036	4.918SerIle: 4.918 ± 0.061	3.727SerLys: 3.727 ± 0.057	7.469SerLeu: 7.469 ± 0.077	1.768SerMet: 1.768 ± 0.034	3.077SerAsn: 3.077 ± 0.052	2.475SerPro: 2.475 ± 0.044	3.207SerGln: 3.207 ± 0.05	2.858SerArg: 2.858 ± 0.042	4.84SerSer: 4.84 ± 0.074	3.583SerThr: 3.583 ± 0.054	4.742SerVal: 4.742 ± 0.062	0.838SerTrp: 0.838 ± 0.024	2.158SerTyr: 2.158 ± 0.044	0.0SerXaa: 0.0 ± 0.0
Thr	4.435ThrAla: 4.435 ± 0.063	0.477ThrCys: 0.477 ± 0.017	3.337ThrAsp: 3.337 ± 0.056	3.167ThrGlu: 3.167 ± 0.05	2.381ThrPhe: 2.381 ± 0.04	4.022ThrGly: 4.022 ± 0.068	1.234ThrHis: 1.234 ± 0.031	3.594ThrIle: 3.594 ± 0.051	2.549ThrLys: 2.549 ± 0.044	6.198ThrLeu: 6.198 ± 0.064	1.161ThrMet: 1.161 ± 0.032	2.32ThrAsn: 2.32 ± 0.046	2.617ThrPro: 2.617 ± 0.044	2.598ThrGln: 2.598 ± 0.049	2.073ThrArg: 2.073 ± 0.041	3.789ThrSer: 3.789 ± 0.06	2.957ThrThr: 2.957 ± 0.052	3.593ThrVal: 3.593 ± 0.059	0.647ThrTrp: 0.647 ± 0.021	1.593ThrTyr: 1.593 ± 0.037	0.0ThrXaa: 0.0 ± 0.0
Val	5.587ValAla: 5.587 ± 0.077	0.707ValCys: 0.707 ± 0.024	4.021ValAsp: 4.021 ± 0.057	3.981ValGlu: 3.981 ± 0.057	2.997ValPhe: 2.997 ± 0.05	4.335ValGly: 4.335 ± 0.066	1.261ValHis: 1.261 ± 0.033	4.784ValIle: 4.784 ± 0.054	3.674ValLys: 3.674 ± 0.061	6.613ValLeu: 6.613 ± 0.076	1.863ValMet: 1.863 ± 0.032	3.403ValAsn: 3.403 ± 0.053	2.423ValPro: 2.423 ± 0.047	2.296ValGln: 2.296 ± 0.044	2.575ValArg: 2.575 ± 0.043	5.034ValSer: 5.034 ± 0.062	4.071ValThr: 4.071 ± 0.07	4.849ValVal: 4.849 ± 0.073	0.704ValTrp: 0.704 ± 0.026	1.836ValTyr: 1.836 ± 0.035	0.0ValXaa: 0.0 ± 0.0
Trp	0.783TrpAla: 0.783 ± 0.025	0.137TrpCys: 0.137 ± 0.01	0.625TrpAsp: 0.625 ± 0.025	0.498TrpGlu: 0.498 ± 0.019	0.58TrpPhe: 0.58 ± 0.022	0.733TrpGly: 0.733 ± 0.023	0.359TrpHis: 0.359 ± 0.016	0.726TrpIle: 0.726 ± 0.022	0.5TrpLys: 0.5 ± 0.02	1.714TrpLeu: 1.714 ± 0.036	0.309TrpMet: 0.309 ± 0.013	0.472TrpAsn: 0.472 ± 0.02	0.469TrpPro: 0.469 ± 0.018	1.041TrpGln: 1.041 ± 0.027	0.641TrpArg: 0.641 ± 0.023	0.803TrpSer: 0.803 ± 0.027	0.545TrpThr: 0.545 ± 0.019	0.859TrpVal: 0.859 ± 0.024	0.183TrpTrp: 0.183 ± 0.012	0.38TrpTyr: 0.38 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.326TyrAla: 2.326 ± 0.036	0.394TyrCys: 0.394 ± 0.015	1.674TyrAsp: 1.674 ± 0.034	1.598TyrGlu: 1.598 ± 0.039	1.626TyrPhe: 1.626 ± 0.036	2.042TyrGly: 2.042 ± 0.041	0.758TyrHis: 0.758 ± 0.022	1.865TyrIle: 1.865 ± 0.036	1.503TyrLys: 1.503 ± 0.031	3.459TyrLeu: 3.459 ± 0.051	0.665TyrMet: 0.665 ± 0.023	1.203TyrAsn: 1.203 ± 0.028	1.34TyrPro: 1.34 ± 0.033	1.976TyrGln: 1.976 ± 0.047	1.603TyrArg: 1.603 ± 0.034	2.315TyrSer: 2.315 ± 0.042	1.523TyrThr: 1.523 ± 0.038	1.922TyrVal: 1.922 ± 0.037	0.482TyrTrp: 0.482 ± 0.018	1.116TyrTyr: 1.116 ± 0.034	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5601 proteins (1496535 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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