Amino acid dipepetide frequency for Fox fecal rhabdovirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.232AlaAla: 6.232 ± 1.868
1.039AlaCys: 1.039 ± 0.613
2.285AlaAsp: 2.285 ± 0.922
5.816AlaGlu: 5.816 ± 2.051
2.077AlaPhe: 2.077 ± 0.472
4.57AlaGly: 4.57 ± 0.897
1.662AlaHis: 1.662 ± 0.496
5.193AlaIle: 5.193 ± 1.162
3.947AlaLys: 3.947 ± 0.97
6.44AlaLeu: 6.44 ± 1.272
2.285AlaMet: 2.285 ± 0.697
2.285AlaAsn: 2.285 ± 1.113
4.985AlaPro: 4.985 ± 1.245
1.246AlaGln: 1.246 ± 0.349
2.7AlaArg: 2.7 ± 1.087
6.855AlaSer: 6.855 ± 1.422
4.362AlaThr: 4.362 ± 1.134
4.155AlaVal: 4.155 ± 0.672
1.454AlaTrp: 1.454 ± 0.439
2.493AlaTyr: 2.493 ± 1.056
0.0AlaXaa: 0.0 ± 0.0
Cys
0.415CysAla: 0.415 ± 0.213
1.039CysCys: 1.039 ± 0.39
0.623CysAsp: 0.623 ± 0.423
2.285CysGlu: 2.285 ± 1.11
1.246CysPhe: 1.246 ± 0.854
0.623CysGly: 0.623 ± 0.264
0.415CysHis: 0.415 ± 0.45
1.039CysIle: 1.039 ± 0.613
0.415CysLys: 0.415 ± 0.343
1.662CysLeu: 1.662 ± 0.446
0.415CysMet: 0.415 ± 0.245
0.208CysAsn: 0.208 ± 0.123
0.415CysPro: 0.415 ± 0.235
0.831CysGln: 0.831 ± 0.271
1.454CysArg: 1.454 ± 0.417
1.662CysSer: 1.662 ± 0.701
0.623CysThr: 0.623 ± 0.799
1.039CysVal: 1.039 ± 0.286
0.208CysTrp: 0.208 ± 0.123
1.246CysTyr: 1.246 ± 0.327
0.0CysXaa: 0.0 ± 0.0
Asp
1.87AspAla: 1.87 ± 0.392
0.623AspCys: 0.623 ± 0.423
3.324AspAsp: 3.324 ± 1.351
2.7AspGlu: 2.7 ± 1.135
2.493AspPhe: 2.493 ± 1.252
2.285AspGly: 2.285 ± 1.176
1.87AspHis: 1.87 ± 0.582
2.7AspIle: 2.7 ± 0.801
2.493AspLys: 2.493 ± 0.678
4.362AspLeu: 4.362 ± 1.283
1.87AspMet: 1.87 ± 0.584
2.908AspAsn: 2.908 ± 0.733
4.57AspPro: 4.57 ± 1.448
1.039AspGln: 1.039 ± 0.461
1.662AspArg: 1.662 ± 0.543
3.739AspSer: 3.739 ± 0.548
3.324AspThr: 3.324 ± 0.841
2.077AspVal: 2.077 ± 0.702
0.623AspTrp: 0.623 ± 0.288
1.246AspTyr: 1.246 ± 0.495
0.0AspXaa: 0.0 ± 0.0
Glu
3.116GluAla: 3.116 ± 1.858
1.246GluCys: 1.246 ± 0.399
2.493GluAsp: 2.493 ± 1.106
6.024GluGlu: 6.024 ± 0.906
3.116GluPhe: 3.116 ± 0.775
4.778GluGly: 4.778 ± 0.75
1.662GluHis: 1.662 ± 0.321
2.908GluIle: 2.908 ± 1.022
3.531GluLys: 3.531 ± 0.889
7.894GluLeu: 7.894 ± 1.359
2.493GluMet: 2.493 ± 0.375
1.662GluAsn: 1.662 ± 0.467
3.116GluPro: 3.116 ± 1.523
1.87GluGln: 1.87 ± 0.561
3.739GluArg: 3.739 ± 0.919
4.985GluSer: 4.985 ± 0.803
1.87GluThr: 1.87 ± 0.625
5.193GluVal: 5.193 ± 1.33
1.454GluTrp: 1.454 ± 0.509
1.454GluTyr: 1.454 ± 0.47
0.0GluXaa: 0.0 ± 0.0
Phe
2.7PheAla: 2.7 ± 0.33
0.831PheCys: 0.831 ± 0.402
1.454PheAsp: 1.454 ± 0.447
2.285PheGlu: 2.285 ± 0.525
2.7PhePhe: 2.7 ± 0.974
3.116PheGly: 3.116 ± 0.725
0.623PheHis: 0.623 ± 0.436
1.039PheIle: 1.039 ± 0.368
2.077PheLys: 2.077 ± 0.533
3.531PheLeu: 3.531 ± 0.855
0.208PheMet: 0.208 ± 0.422
1.039PheAsn: 1.039 ± 0.435
2.493PhePro: 2.493 ± 1.04
1.039PheGln: 1.039 ± 0.453
1.87PheArg: 1.87 ± 0.719
4.155PheSer: 4.155 ± 1.82
2.908PheThr: 2.908 ± 0.539
1.662PheVal: 1.662 ± 0.47
0.623PheTrp: 0.623 ± 0.27
0.831PheTyr: 0.831 ± 0.37
0.0PheXaa: 0.0 ± 0.0
Gly
4.985GlyAla: 4.985 ± 0.926
2.285GlyCys: 2.285 ± 0.426
5.401GlyAsp: 5.401 ± 1.247
3.947GlyGlu: 3.947 ± 0.79
2.7GlyPhe: 2.7 ± 0.665
4.778GlyGly: 4.778 ± 1.206
1.039GlyHis: 1.039 ± 0.461
3.324GlyIle: 3.324 ± 1.234
4.155GlyLys: 4.155 ± 0.849
6.855GlyLeu: 6.855 ± 1.191
0.623GlyMet: 0.623 ± 0.427
2.908GlyAsn: 2.908 ± 0.653
1.662GlyPro: 1.662 ± 0.592
2.7GlyGln: 2.7 ± 0.616
3.116GlyArg: 3.116 ± 0.752
5.193GlySer: 5.193 ± 0.871
2.285GlyThr: 2.285 ± 0.948
4.985GlyVal: 4.985 ± 0.895
1.246GlyTrp: 1.246 ± 0.367
1.87GlyTyr: 1.87 ± 0.699
0.0GlyXaa: 0.0 ± 0.0
His
1.87HisAla: 1.87 ± 0.842
0.415HisCys: 0.415 ± 0.533
1.246HisAsp: 1.246 ± 0.52
0.623HisGlu: 0.623 ± 0.439
0.623HisPhe: 0.623 ± 0.429
2.077HisGly: 2.077 ± 0.396
0.415HisHis: 0.415 ± 0.245
1.454HisIle: 1.454 ± 0.859
1.039HisLys: 1.039 ± 0.435
3.116HisLeu: 3.116 ± 0.682
0.415HisMet: 0.415 ± 0.213
0.831HisAsn: 0.831 ± 0.37
2.285HisPro: 2.285 ± 0.782
0.208HisGln: 0.208 ± 0.422
1.662HisArg: 1.662 ± 1.145
3.116HisSer: 3.116 ± 0.749
0.623HisThr: 0.623 ± 0.439
1.039HisVal: 1.039 ± 0.286
0.623HisTrp: 0.623 ± 0.368
0.208HisTyr: 0.208 ± 0.123
0.0HisXaa: 0.0 ± 0.0
Ile
5.193IleAla: 5.193 ± 1.288
0.208IleCys: 0.208 ± 0.266
3.116IleAsp: 3.116 ± 1.195
2.285IleGlu: 2.285 ± 0.991
1.87IlePhe: 1.87 ± 0.846
4.155IleGly: 4.155 ± 1.331
1.246IleHis: 1.246 ± 0.363
4.985IleIle: 4.985 ± 1.616
3.947IleLys: 3.947 ± 0.787
5.816IleLeu: 5.816 ± 0.887
1.246IleMet: 1.246 ± 0.387
1.662IleAsn: 1.662 ± 0.687
3.324IlePro: 3.324 ± 0.984
1.454IleGln: 1.454 ± 0.677
3.324IleArg: 3.324 ± 0.887
6.44IleSer: 6.44 ± 1.365
4.155IleThr: 4.155 ± 0.834
3.324IleVal: 3.324 ± 0.711
0.831IleTrp: 0.831 ± 0.339
1.87IleTyr: 1.87 ± 1.053
0.0IleXaa: 0.0 ± 0.0
Lys
4.155LysAla: 4.155 ± 1.387
1.039LysCys: 1.039 ± 0.394
2.493LysAsp: 2.493 ± 0.945
5.401LysGlu: 5.401 ± 1.714
3.739LysPhe: 3.739 ± 1.214
4.985LysGly: 4.985 ± 0.891
1.039LysHis: 1.039 ± 0.413
2.7LysIle: 2.7 ± 0.614
3.531LysLys: 3.531 ± 1.438
2.908LysLeu: 2.908 ± 0.402
1.454LysMet: 1.454 ± 0.701
1.662LysAsn: 1.662 ± 0.553
3.116LysPro: 3.116 ± 1.018
1.246LysGln: 1.246 ± 0.491
2.493LysArg: 2.493 ± 0.516
3.531LysSer: 3.531 ± 1.01
3.116LysThr: 3.116 ± 1.247
3.531LysVal: 3.531 ± 1.084
1.246LysTrp: 1.246 ± 0.425
1.454LysTyr: 1.454 ± 0.822
0.0LysXaa: 0.0 ± 0.0
Leu
6.647LeuAla: 6.647 ± 1.154
1.662LeuCys: 1.662 ± 0.496
3.531LeuAsp: 3.531 ± 1.115
6.855LeuGlu: 6.855 ± 1.47
3.531LeuPhe: 3.531 ± 1.111
6.855LeuGly: 6.855 ± 0.718
3.324LeuHis: 3.324 ± 1.095
5.401LeuIle: 5.401 ± 1.98
4.985LeuLys: 4.985 ± 1.528
9.555LeuLeu: 9.555 ± 0.449
2.077LeuMet: 2.077 ± 0.756
2.7LeuAsn: 2.7 ± 1.129
5.401LeuPro: 5.401 ± 0.643
3.324LeuGln: 3.324 ± 0.543
6.855LeuArg: 6.855 ± 1.148
9.763LeuSer: 9.763 ± 1.777
6.647LeuThr: 6.647 ± 1.479
5.401LeuVal: 5.401 ± 1.527
1.662LeuTrp: 1.662 ± 0.613
2.285LeuTyr: 2.285 ± 0.501
0.0LeuXaa: 0.0 ± 0.0
Met
0.831MetAla: 0.831 ± 0.273
1.039MetCys: 1.039 ± 0.286
0.831MetAsp: 0.831 ± 0.273
1.87MetGlu: 1.87 ± 0.476
1.039MetPhe: 1.039 ± 0.459
1.246MetGly: 1.246 ± 0.763
0.415MetHis: 0.415 ± 0.406
2.077MetIle: 2.077 ± 0.598
1.454MetLys: 1.454 ± 0.447
2.908MetLeu: 2.908 ± 0.625
0.831MetMet: 0.831 ± 0.402
1.246MetAsn: 1.246 ± 0.46
0.831MetPro: 0.831 ± 0.555
0.623MetGln: 0.623 ± 0.262
2.077MetArg: 2.077 ± 0.812
3.116MetSer: 3.116 ± 1.44
1.039MetThr: 1.039 ± 0.453
1.454MetVal: 1.454 ± 0.467
0.208MetTrp: 0.208 ± 0.123
0.623MetTyr: 0.623 ± 0.264
0.0MetXaa: 0.0 ± 0.0
Asn
2.077AsnAla: 2.077 ± 0.541
0.415AsnCys: 0.415 ± 0.406
2.285AsnAsp: 2.285 ± 0.852
2.7AsnGlu: 2.7 ± 0.975
1.246AsnPhe: 1.246 ± 0.448
2.077AsnGly: 2.077 ± 0.971
0.623AsnHis: 0.623 ± 0.427
2.285AsnIle: 2.285 ± 1.446
1.039AsnLys: 1.039 ± 0.286
2.908AsnLeu: 2.908 ± 0.872
0.415AsnMet: 0.415 ± 0.244
1.246AsnAsn: 1.246 ± 0.503
2.285AsnPro: 2.285 ± 0.548
1.87AsnGln: 1.87 ± 0.7
0.415AsnArg: 0.415 ± 0.456
1.87AsnSer: 1.87 ± 0.844
1.87AsnThr: 1.87 ± 0.625
2.908AsnVal: 2.908 ± 0.454
1.87AsnTrp: 1.87 ± 0.413
1.87AsnTyr: 1.87 ± 0.487
0.0AsnXaa: 0.0 ± 0.0
Pro
3.739ProAla: 3.739 ± 1.451
0.831ProCys: 0.831 ± 0.749
4.155ProAsp: 4.155 ± 0.791
4.778ProGlu: 4.778 ± 0.948
1.454ProPhe: 1.454 ± 0.36
2.285ProGly: 2.285 ± 0.54
1.87ProHis: 1.87 ± 0.723
4.155ProIle: 4.155 ± 1.025
3.947ProLys: 3.947 ± 1.163
4.155ProLeu: 4.155 ± 0.967
1.662ProMet: 1.662 ± 0.579
0.831ProAsn: 0.831 ± 0.494
4.362ProPro: 4.362 ± 2.289
2.7ProGln: 2.7 ± 0.762
3.116ProArg: 3.116 ± 0.884
5.401ProSer: 5.401 ± 1.013
2.285ProThr: 2.285 ± 0.525
3.324ProVal: 3.324 ± 0.848
0.831ProTrp: 0.831 ± 0.445
1.454ProTyr: 1.454 ± 0.55
0.0ProXaa: 0.0 ± 0.0
Gln
1.454GlnAla: 1.454 ± 0.562
0.208GlnCys: 0.208 ± 0.123
1.662GlnAsp: 1.662 ± 0.646
0.831GlnGlu: 0.831 ± 0.339
1.039GlnPhe: 1.039 ± 0.451
1.87GlnGly: 1.87 ± 0.389
1.039GlnHis: 1.039 ± 0.452
1.454GlnIle: 1.454 ± 0.467
1.246GlnLys: 1.246 ± 0.763
3.739GlnLeu: 3.739 ± 0.801
0.208GlnMet: 0.208 ± 0.422
1.039GlnAsn: 1.039 ± 0.465
1.662GlnPro: 1.662 ± 0.523
0.208GlnGln: 0.208 ± 0.123
2.285GlnArg: 2.285 ± 0.755
3.324GlnSer: 3.324 ± 0.549
1.039GlnThr: 1.039 ± 0.465
2.908GlnVal: 2.908 ± 1.157
0.208GlnTrp: 0.208 ± 0.123
1.246GlnTyr: 1.246 ± 0.536
0.0GlnXaa: 0.0 ± 0.0
Arg
5.401ArgAla: 5.401 ± 0.875
0.415ArgCys: 0.415 ± 0.244
1.454ArgAsp: 1.454 ± 0.47
3.116ArgGlu: 3.116 ± 0.67
2.077ArgPhe: 2.077 ± 0.677
3.947ArgGly: 3.947 ± 0.873
1.454ArgHis: 1.454 ± 0.74
3.947ArgIle: 3.947 ± 0.906
2.908ArgLys: 2.908 ± 0.773
6.232ArgLeu: 6.232 ± 0.607
1.87ArgMet: 1.87 ± 0.61
0.831ArgAsn: 0.831 ± 0.243
2.908ArgPro: 2.908 ± 1.192
1.246ArgGln: 1.246 ± 0.645
3.531ArgArg: 3.531 ± 1.239
3.116ArgSer: 3.116 ± 0.877
2.077ArgThr: 2.077 ± 0.394
3.739ArgVal: 3.739 ± 1.319
1.454ArgTrp: 1.454 ± 0.595
1.87ArgTyr: 1.87 ± 1.023
0.0ArgXaa: 0.0 ± 0.0
Ser
8.932SerAla: 8.932 ± 1.027
1.662SerCys: 1.662 ± 0.883
4.362SerAsp: 4.362 ± 1.174
4.778SerGlu: 4.778 ± 0.767
1.039SerPhe: 1.039 ± 0.594
4.155SerGly: 4.155 ± 1.291
2.077SerHis: 2.077 ± 0.65
6.647SerIle: 6.647 ± 0.779
3.947SerLys: 3.947 ± 1.324
8.517SerLeu: 8.517 ± 1.767
2.077SerMet: 2.077 ± 0.47
4.57SerAsn: 4.57 ± 1.502
4.778SerPro: 4.778 ± 0.867
2.285SerGln: 2.285 ± 1.23
4.155SerArg: 4.155 ± 0.542
9.348SerSer: 9.348 ± 1.085
5.816SerThr: 5.816 ± 0.846
6.647SerVal: 6.647 ± 1.536
1.662SerTrp: 1.662 ± 0.539
3.324SerTyr: 3.324 ± 0.642
0.0SerXaa: 0.0 ± 0.0
Thr
4.362ThrAla: 4.362 ± 0.899
0.208ThrCys: 0.208 ± 0.266
2.077ThrAsp: 2.077 ± 0.68
2.493ThrGlu: 2.493 ± 0.414
1.039ThrPhe: 1.039 ± 0.825
3.947ThrGly: 3.947 ± 0.849
1.454ThrHis: 1.454 ± 0.467
3.116ThrIle: 3.116 ± 0.961
4.778ThrLys: 4.778 ± 1.007
4.778ThrLeu: 4.778 ± 1.57
1.454ThrMet: 1.454 ± 0.495
2.285ThrAsn: 2.285 ± 0.64
3.324ThrPro: 3.324 ± 0.899
1.87ThrGln: 1.87 ± 0.665
2.493ThrArg: 2.493 ± 0.615
6.44ThrSer: 6.44 ± 1.435
2.7ThrThr: 2.7 ± 0.545
3.116ThrVal: 3.116 ± 0.919
0.623ThrTrp: 0.623 ± 0.264
1.662ThrTyr: 1.662 ± 1.249
0.0ThrXaa: 0.0 ± 0.0
Val
4.155ValAla: 4.155 ± 0.697
1.662ValCys: 1.662 ± 0.675
2.908ValAsp: 2.908 ± 0.625
3.739ValGlu: 3.739 ± 0.956
1.246ValPhe: 1.246 ± 0.578
4.155ValGly: 4.155 ± 0.775
0.831ValHis: 0.831 ± 0.494
3.947ValIle: 3.947 ± 0.969
2.7ValLys: 2.7 ± 1.006
7.478ValLeu: 7.478 ± 1.615
1.662ValMet: 1.662 ± 0.498
2.493ValAsn: 2.493 ± 0.351
2.908ValPro: 2.908 ± 0.852
1.039ValGln: 1.039 ± 0.438
4.155ValArg: 4.155 ± 1.204
5.193ValSer: 5.193 ± 1.066
3.947ValThr: 3.947 ± 1.234
4.778ValVal: 4.778 ± 2.263
1.039ValTrp: 1.039 ± 0.663
2.908ValTyr: 2.908 ± 0.669
0.0ValXaa: 0.0 ± 0.0
Trp
1.662TrpAla: 1.662 ± 0.835
0.415TrpCys: 0.415 ± 0.245
0.831TrpAsp: 0.831 ± 0.494
1.039TrpGlu: 1.039 ± 0.578
1.039TrpPhe: 1.039 ± 0.507
2.077TrpGly: 2.077 ± 0.815
0.208TrpHis: 0.208 ± 0.257
0.831TrpIle: 0.831 ± 0.349
1.246TrpLys: 1.246 ± 0.515
0.831TrpLeu: 0.831 ± 0.37
1.246TrpMet: 1.246 ± 0.515
0.831TrpAsn: 0.831 ± 0.491
0.831TrpPro: 0.831 ± 0.491
0.208TrpGln: 0.208 ± 0.228
1.039TrpArg: 1.039 ± 0.679
1.454TrpSer: 1.454 ± 0.655
1.662TrpThr: 1.662 ± 0.523
0.831TrpVal: 0.831 ± 0.558
0.0TrpTrp: 0.0 ± 0.0
0.208TrpTyr: 0.208 ± 0.123
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.285TyrAla: 2.285 ± 0.705
0.623TyrCys: 0.623 ± 0.264
1.246TyrAsp: 1.246 ± 0.973
1.039TyrGlu: 1.039 ± 0.52
1.87TyrPhe: 1.87 ± 0.805
2.077TyrGly: 2.077 ± 0.435
0.623TyrHis: 0.623 ± 0.532
1.246TyrIle: 1.246 ± 1.022
1.454TyrLys: 1.454 ± 0.417
4.778TyrLeu: 4.778 ± 0.695
1.039TyrMet: 1.039 ± 0.435
1.039TyrAsn: 1.039 ± 0.435
2.077TyrPro: 2.077 ± 1.285
1.662TyrGln: 1.662 ± 0.647
1.662TyrArg: 1.662 ± 0.913
2.077TyrSer: 2.077 ± 0.906
1.87TyrThr: 1.87 ± 0.819
0.831TyrVal: 0.831 ± 0.494
0.623TyrTrp: 0.623 ± 0.262
0.623TyrTyr: 0.623 ± 0.284
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (4815 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski