Amino acid dipepetide frequency for Hortaea werneckii

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.965AlaAla: 9.965 ± 0.048	1.06AlaCys: 1.06 ± 0.014	4.569AlaAsp: 4.569 ± 0.023	5.837AlaGlu: 5.837 ± 0.034	3.284AlaPhe: 3.284 ± 0.022	6.904AlaGly: 6.904 ± 0.035	1.849AlaHis: 1.849 ± 0.016	3.919AlaIle: 3.919 ± 0.026	4.358AlaLys: 4.358 ± 0.031	7.612AlaLeu: 7.612 ± 0.037	2.114AlaMet: 2.114 ± 0.017	3.235AlaAsn: 3.235 ± 0.021	5.281AlaPro: 5.281 ± 0.036	4.042AlaGln: 4.042 ± 0.026	5.034AlaArg: 5.034 ± 0.024	7.817AlaSer: 7.817 ± 0.045	5.531AlaThr: 5.531 ± 0.028	5.381AlaVal: 5.381 ± 0.028	1.187AlaTrp: 1.187 ± 0.013	2.284AlaTyr: 2.284 ± 0.019	0.0AlaXaa: 0.0 ± 0.0
Cys	0.902CysAla: 0.902 ± 0.012	0.207CysCys: 0.207 ± 0.006	0.606CysAsp: 0.606 ± 0.009	0.585CysGlu: 0.585 ± 0.008	0.511CysPhe: 0.511 ± 0.008	0.907CysGly: 0.907 ± 0.013	0.287CysHis: 0.287 ± 0.007	0.6CysIle: 0.6 ± 0.009	0.478CysLys: 0.478 ± 0.009	1.137CysLeu: 1.137 ± 0.014	0.263CysMet: 0.263 ± 0.006	0.425CysAsn: 0.425 ± 0.008	0.621CysPro: 0.621 ± 0.009	0.423CysGln: 0.423 ± 0.009	0.666CysArg: 0.666 ± 0.009	0.828CysSer: 0.828 ± 0.011	0.636CysThr: 0.636 ± 0.009	0.726CysVal: 0.726 ± 0.009	0.202CysTrp: 0.202 ± 0.006	0.347CysTyr: 0.347 ± 0.006	0.0CysXaa: 0.0 ± 0.0
Asp	5.101AspAla: 5.101 ± 0.025	0.615AspCys: 0.615 ± 0.009	4.378AspAsp: 4.378 ± 0.037	4.871AspGlu: 4.871 ± 0.031	2.26AspPhe: 2.26 ± 0.015	4.409AspGly: 4.409 ± 0.023	1.229AspHis: 1.229 ± 0.014	2.602AspIle: 2.602 ± 0.019	2.17AspLys: 2.17 ± 0.019	4.98AspLeu: 4.98 ± 0.03	1.309AspMet: 1.309 ± 0.014	1.757AspAsn: 1.757 ± 0.016	3.318AspPro: 3.318 ± 0.023	2.063AspGln: 2.063 ± 0.017	3.108AspArg: 3.108 ± 0.024	3.98AspSer: 3.98 ± 0.026	2.844AspThr: 2.844 ± 0.022	3.76AspVal: 3.76 ± 0.022	0.891AspTrp: 0.891 ± 0.012	1.644AspTyr: 1.644 ± 0.015	0.0AspXaa: 0.0 ± 0.0
Glu	5.846GluAla: 5.846 ± 0.037	0.565GluCys: 0.565 ± 0.01	4.634GluAsp: 4.634 ± 0.029	5.951GluGlu: 5.951 ± 0.047	1.729GluPhe: 1.729 ± 0.016	4.685GluGly: 4.685 ± 0.025	1.489GluHis: 1.489 ± 0.015	2.621GluIle: 2.621 ± 0.018	3.915GluLys: 3.915 ± 0.029	5.006GluLeu: 5.006 ± 0.027	1.589GluMet: 1.589 ± 0.014	2.199GluAsn: 2.199 ± 0.017	2.866GluPro: 2.866 ± 0.021	3.007GluGln: 3.007 ± 0.023	4.411GluArg: 4.411 ± 0.029	4.188GluSer: 4.188 ± 0.028	3.472GluThr: 3.472 ± 0.021	3.648GluVal: 3.648 ± 0.023	0.878GluTrp: 0.878 ± 0.011	1.62GluTyr: 1.62 ± 0.015	0.0GluXaa: 0.0 ± 0.0
Phe	3.262PheAla: 3.262 ± 0.022	0.513PheCys: 0.513 ± 0.009	2.173PheAsp: 2.173 ± 0.016	2.103PheGlu: 2.103 ± 0.019	1.509PhePhe: 1.509 ± 0.017	2.973PheGly: 2.973 ± 0.024	0.83PheHis: 0.83 ± 0.009	1.517PheIle: 1.517 ± 0.015	1.385PheLys: 1.385 ± 0.015	3.151PheLeu: 3.151 ± 0.025	0.759PheMet: 0.759 ± 0.01	1.374PheAsn: 1.374 ± 0.014	1.801PhePro: 1.801 ± 0.014	1.308PheGln: 1.308 ± 0.016	1.799PheArg: 1.799 ± 0.015	2.705PheSer: 2.705 ± 0.02	2.105PheThr: 2.105 ± 0.018	2.239PheVal: 2.239 ± 0.02	0.616PheTrp: 0.616 ± 0.01	1.081PheTyr: 1.081 ± 0.012	0.0PheXaa: 0.0 ± 0.0
Gly	5.971GlyAla: 5.971 ± 0.033	0.861GlyCys: 0.861 ± 0.012	3.973GlyAsp: 3.973 ± 0.025	4.392GlyGlu: 4.392 ± 0.029	2.882GlyPhe: 2.882 ± 0.023	7.559GlyGly: 7.559 ± 0.058	1.721GlyHis: 1.721 ± 0.017	3.348GlyIle: 3.348 ± 0.023	3.894GlyLys: 3.894 ± 0.028	6.194GlyLeu: 6.194 ± 0.03	1.969GlyMet: 1.969 ± 0.016	2.77GlyAsn: 2.77 ± 0.021	3.373GlyPro: 3.373 ± 0.026	3.007GlyGln: 3.007 ± 0.022	4.445GlyArg: 4.445 ± 0.025	6.19GlySer: 6.19 ± 0.036	4.211GlyThr: 4.211 ± 0.028	4.542GlyVal: 4.542 ± 0.023	1.263GlyTrp: 1.263 ± 0.015	2.242GlyTyr: 2.242 ± 0.021	0.0GlyXaa: 0.0 ± 0.0
His	2.007HisAla: 2.007 ± 0.018	0.32HisCys: 0.32 ± 0.007	1.375HisAsp: 1.375 ± 0.013	1.424HisGlu: 1.424 ± 0.015	0.913HisPhe: 0.913 ± 0.01	1.771HisGly: 1.771 ± 0.018	0.904HisHis: 0.904 ± 0.016	1.012HisIle: 1.012 ± 0.012	0.856HisLys: 0.856 ± 0.012	2.205HisLeu: 2.205 ± 0.02	0.484HisMet: 0.484 ± 0.008	0.822HisAsn: 0.822 ± 0.011	1.683HisPro: 1.683 ± 0.015	1.079HisGln: 1.079 ± 0.015	1.476HisArg: 1.476 ± 0.014	1.812HisSer: 1.812 ± 0.017	1.219HisThr: 1.219 ± 0.014	1.43HisVal: 1.43 ± 0.013	0.359HisTrp: 0.359 ± 0.007	0.69HisTyr: 0.69 ± 0.009	0.0HisXaa: 0.0 ± 0.0
Ile	3.946IleAla: 3.946 ± 0.024	0.651IleCys: 0.651 ± 0.008	2.602IleAsp: 2.602 ± 0.019	2.578IleGlu: 2.578 ± 0.02	1.708IlePhe: 1.708 ± 0.018	3.041IleGly: 3.041 ± 0.024	1.013IleHis: 1.013 ± 0.012	1.94IleIle: 1.94 ± 0.018	1.84IleLys: 1.84 ± 0.016	3.789IleLeu: 3.789 ± 0.024	0.942IleMet: 0.942 ± 0.01	1.603IleAsn: 1.603 ± 0.015	2.579IlePro: 2.579 ± 0.018	1.642IleGln: 1.642 ± 0.014	2.439IleArg: 2.439 ± 0.02	3.23IleSer: 3.23 ± 0.019	2.524IleThr: 2.524 ± 0.019	2.78IleVal: 2.78 ± 0.022	0.645IleTrp: 0.645 ± 0.009	1.256IleTyr: 1.256 ± 0.013	0.0IleXaa: 0.0 ± 0.0
Lys	4.545LysAla: 4.545 ± 0.027	0.457LysCys: 0.457 ± 0.008	2.838LysAsp: 2.838 ± 0.022	3.431LysGlu: 3.431 ± 0.029	1.25LysPhe: 1.25 ± 0.013	3.296LysGly: 3.296 ± 0.028	1.155LysHis: 1.155 ± 0.013	1.886LysIle: 1.886 ± 0.016	3.324LysLys: 3.324 ± 0.032	3.847LysLeu: 3.847 ± 0.027	1.073LysMet: 1.073 ± 0.011	1.584LysAsn: 1.584 ± 0.015	2.903LysPro: 2.903 ± 0.028	2.196LysGln: 2.196 ± 0.017	3.608LysArg: 3.608 ± 0.028	3.298LysSer: 3.298 ± 0.027	2.72LysThr: 2.72 ± 0.02	2.787LysVal: 2.787 ± 0.019	0.637LysTrp: 0.637 ± 0.008	1.255LysTyr: 1.255 ± 0.014	0.0LysXaa: 0.0 ± 0.0
Leu	7.735LeuAla: 7.735 ± 0.036	1.103LeuCys: 1.103 ± 0.013	4.89LeuAsp: 4.89 ± 0.029	5.241LeuGlu: 5.241 ± 0.029	3.027LeuPhe: 3.027 ± 0.02	5.845LeuGly: 5.845 ± 0.028	2.157LeuHis: 2.157 ± 0.016	3.463LeuIle: 3.463 ± 0.023	3.967LeuLys: 3.967 ± 0.026	7.654LeuLeu: 7.654 ± 0.053	1.762LeuMet: 1.762 ± 0.016	2.992LeuAsn: 2.992 ± 0.023	5.496LeuPro: 5.496 ± 0.032	3.925LeuGln: 3.925 ± 0.027	5.455LeuArg: 5.455 ± 0.037	6.674LeuSer: 6.674 ± 0.038	4.592LeuThr: 4.592 ± 0.026	4.883LeuVal: 4.883 ± 0.031	1.109LeuTrp: 1.109 ± 0.014	2.231LeuTyr: 2.231 ± 0.018	0.0LeuXaa: 0.0 ± 0.0
Met	2.326MetAla: 2.326 ± 0.017	0.241MetCys: 0.241 ± 0.006	1.302MetAsp: 1.302 ± 0.012	1.332MetGlu: 1.332 ± 0.012	0.745MetPhe: 0.745 ± 0.009	1.591MetGly: 1.591 ± 0.017	0.547MetHis: 0.547 ± 0.01	0.922MetIle: 0.922 ± 0.011	1.057MetLys: 1.057 ± 0.011	1.968MetLeu: 1.968 ± 0.015	0.615MetMet: 0.615 ± 0.009	0.834MetAsn: 0.834 ± 0.01	1.492MetPro: 1.492 ± 0.018	1.07MetGln: 1.07 ± 0.014	1.368MetArg: 1.368 ± 0.012	1.902MetSer: 1.902 ± 0.016	1.309MetThr: 1.309 ± 0.014	1.264MetVal: 1.264 ± 0.014	0.267MetTrp: 0.267 ± 0.006	0.555MetTyr: 0.555 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	3.488AsnAla: 3.488 ± 0.022	0.39AsnCys: 0.39 ± 0.007	2.022AsnAsp: 2.022 ± 0.016	2.13AsnGlu: 2.13 ± 0.019	1.333AsnPhe: 1.333 ± 0.013	3.252AsnGly: 3.252 ± 0.027	0.826AsnHis: 0.826 ± 0.011	1.753AsnIle: 1.753 ± 0.016	1.486AsnLys: 1.486 ± 0.013	3.059AsnLeu: 3.059 ± 0.019	0.825AsnMet: 0.825 ± 0.011	1.459AsnAsn: 1.459 ± 0.017	2.361AsnPro: 2.361 ± 0.02	1.376AsnGln: 1.376 ± 0.015	1.826AsnArg: 1.826 ± 0.014	2.582AsnSer: 2.582 ± 0.023	2.2AsnThr: 2.2 ± 0.019	2.367AsnVal: 2.367 ± 0.018	0.526AsnTrp: 0.526 ± 0.007	1.036AsnTyr: 1.036 ± 0.011	0.0AsnXaa: 0.0 ± 0.0
Pro	5.78ProAla: 5.78 ± 0.038	0.443ProCys: 0.443 ± 0.009	3.171ProAsp: 3.171 ± 0.021	3.927ProGlu: 3.927 ± 0.025	1.971ProPhe: 1.971 ± 0.016	4.077ProGly: 4.077 ± 0.023	1.407ProHis: 1.407 ± 0.015	2.267ProIle: 2.267 ± 0.016	2.784ProLys: 2.784 ± 0.024	4.479ProLeu: 4.479 ± 0.024	1.141ProMet: 1.141 ± 0.011	2.284ProAsn: 2.284 ± 0.017	5.729ProPro: 5.729 ± 0.07	2.901ProGln: 2.901 ± 0.029	3.211ProArg: 3.211 ± 0.023	6.27ProSer: 6.27 ± 0.046	4.134ProThr: 4.134 ± 0.026	3.307ProVal: 3.307 ± 0.023	0.722ProTrp: 0.722 ± 0.01	1.594ProTyr: 1.594 ± 0.018	0.0ProXaa: 0.0 ± 0.0
Gln	4.045GlnAla: 4.045 ± 0.026	0.431GlnCys: 0.431 ± 0.008	2.344GlnAsp: 2.344 ± 0.015	2.708GlnGlu: 2.708 ± 0.02	1.153GlnPhe: 1.153 ± 0.012	2.815GlnGly: 2.815 ± 0.021	1.286GlnHis: 1.286 ± 0.017	1.74GlnIle: 1.74 ± 0.014	2.143GlnLys: 2.143 ± 0.02	3.456GlnLeu: 3.456 ± 0.025	1.022GlnMet: 1.022 ± 0.012	1.662GlnAsn: 1.662 ± 0.016	3.087GlnPro: 3.087 ± 0.029	3.663GlnGln: 3.663 ± 0.046	3.036GlnArg: 3.036 ± 0.023	3.362GlnSer: 3.362 ± 0.024	2.619GlnThr: 2.619 ± 0.018	2.17GlnVal: 2.17 ± 0.017	0.629GlnTrp: 0.629 ± 0.009	1.267GlnTyr: 1.267 ± 0.014	0.0GlnXaa: 0.0 ± 0.0
Arg	4.785ArgAla: 4.785 ± 0.029	0.653ArgCys: 0.653 ± 0.01	3.276ArgAsp: 3.276 ± 0.023	4.117ArgGlu: 4.117 ± 0.03	2.034ArgPhe: 2.034 ± 0.018	3.821ArgGly: 3.821 ± 0.023	1.575ArgHis: 1.575 ± 0.016	2.598ArgIle: 2.598 ± 0.018	3.709ArgLys: 3.709 ± 0.026	5.177ArgLeu: 5.177 ± 0.034	1.422ArgMet: 1.422 ± 0.015	2.179ArgAsn: 2.179 ± 0.019	3.618ArgPro: 3.618 ± 0.029	2.929ArgGln: 2.929 ± 0.023	5.124ArgArg: 5.124 ± 0.034	4.822ArgSer: 4.822 ± 0.033	3.292ArgThr: 3.292 ± 0.02	3.047ArgVal: 3.047 ± 0.02	0.911ArgTrp: 0.911 ± 0.01	1.56ArgTyr: 1.56 ± 0.014	0.0ArgXaa: 0.0 ± 0.0
Ser	7.315SerAla: 7.315 ± 0.042	0.763SerCys: 0.763 ± 0.01	4.191SerAsp: 4.191 ± 0.027	4.346SerGlu: 4.346 ± 0.026	2.771SerPhe: 2.771 ± 0.019	6.144SerGly: 6.144 ± 0.039	1.846SerHis: 1.846 ± 0.017	3.412SerIle: 3.412 ± 0.021	3.707SerLys: 3.707 ± 0.025	6.568SerLeu: 6.568 ± 0.035	1.814SerMet: 1.814 ± 0.017	3.05SerAsn: 3.05 ± 0.022	5.388SerPro: 5.388 ± 0.04	3.431SerGln: 3.431 ± 0.028	4.747SerArg: 4.747 ± 0.032	9.028SerSer: 9.028 ± 0.089	5.674SerThr: 5.674 ± 0.05	4.286SerVal: 4.286 ± 0.029	1.068SerTrp: 1.068 ± 0.012	2.037SerTyr: 2.037 ± 0.018	0.0SerXaa: 0.0 ± 0.0
Thr	5.661ThrAla: 5.661 ± 0.028	0.707ThrCys: 0.707 ± 0.011	2.8ThrAsp: 2.8 ± 0.019	3.106ThrGlu: 3.106 ± 0.024	2.212ThrPhe: 2.212 ± 0.018	4.437ThrGly: 4.437 ± 0.03	1.279ThrHis: 1.279 ± 0.013	2.698ThrIle: 2.698 ± 0.021	2.496ThrLys: 2.496 ± 0.017	4.991ThrLeu: 4.991 ± 0.028	1.247ThrMet: 1.247 ± 0.014	2.166ThrAsn: 2.166 ± 0.019	4.382ThrPro: 4.382 ± 0.026	2.281ThrGln: 2.281 ± 0.017	2.931ThrArg: 2.931 ± 0.017	5.563ThrSer: 5.563 ± 0.049	4.385ThrThr: 4.385 ± 0.047	3.545ThrVal: 3.545 ± 0.027	0.809ThrTrp: 0.809 ± 0.011	1.617ThrTyr: 1.617 ± 0.017	0.0ThrXaa: 0.0 ± 0.0
Val	5.163ValAla: 5.163 ± 0.026	0.767ValCys: 0.767 ± 0.012	3.572ValAsp: 3.572 ± 0.023	3.816ValGlu: 3.816 ± 0.023	2.251ValPhe: 2.251 ± 0.018	4.144ValGly: 4.144 ± 0.026	1.342ValHis: 1.342 ± 0.014	2.48ValIle: 2.48 ± 0.019	2.781ValLys: 2.781 ± 0.023	5.112ValLeu: 5.112 ± 0.036	1.349ValMet: 1.349 ± 0.012	2.179ValAsn: 2.179 ± 0.018	3.511ValPro: 3.511 ± 0.022	2.492ValGln: 2.492 ± 0.018	3.418ValArg: 3.418 ± 0.025	4.33ValSer: 4.33 ± 0.028	3.296ValThr: 3.296 ± 0.026	3.923ValVal: 3.923 ± 0.028	0.856ValTrp: 0.856 ± 0.012	1.666ValTyr: 1.666 ± 0.013	0.0ValXaa: 0.0 ± 0.0
Trp	1.119TrpAla: 1.119 ± 0.014	0.199TrpCys: 0.199 ± 0.005	0.866TrpAsp: 0.866 ± 0.012	0.828TrpGlu: 0.828 ± 0.011	0.525TrpPhe: 0.525 ± 0.008	0.899TrpGly: 0.899 ± 0.012	0.373TrpHis: 0.373 ± 0.007	0.713TrpIle: 0.713 ± 0.01	0.727TrpLys: 0.727 ± 0.01	1.326TrpLeu: 1.326 ± 0.014	0.383TrpMet: 0.383 ± 0.007	0.589TrpAsn: 0.589 ± 0.009	0.631TrpPro: 0.631 ± 0.01	0.674TrpGln: 0.674 ± 0.009	0.995TrpArg: 0.995 ± 0.012	1.034TrpSer: 1.034 ± 0.012	0.911TrpThr: 0.911 ± 0.01	0.785TrpVal: 0.785 ± 0.009	0.268TrpTrp: 0.268 ± 0.006	0.434TrpTyr: 0.434 ± 0.007	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.303TyrAla: 2.303 ± 0.019	0.408TyrCys: 0.408 ± 0.008	1.708TyrAsp: 1.708 ± 0.017	1.597TyrGlu: 1.597 ± 0.013	1.135TyrPhe: 1.135 ± 0.011	2.235TyrGly: 2.235 ± 0.02	0.724TyrHis: 0.724 ± 0.01	1.255TyrIle: 1.255 ± 0.014	1.011TyrLys: 1.011 ± 0.012	2.492TyrLeu: 2.492 ± 0.02	0.625TyrMet: 0.625 ± 0.009	1.133TyrAsn: 1.133 ± 0.013	1.479TyrPro: 1.479 ± 0.014	1.13TyrGln: 1.13 ± 0.012	1.554TyrArg: 1.554 ± 0.014	1.971TyrSer: 1.971 ± 0.018	1.64TyrThr: 1.64 ± 0.017	1.578TyrVal: 1.578 ± 0.015	0.436TyrTrp: 0.436 ± 0.008	0.954TyrTyr: 0.954 ± 0.012	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 16466 proteins (8038627 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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