Amino acid dipepetide frequency for Bat polyomavirus 5b

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.383AlaAla: 6.383 ± 5.217
2.128AlaCys: 2.128 ± 0.713
0.709AlaAsp: 0.709 ± 0.6
7.092AlaGlu: 7.092 ± 4.366
0.709AlaPhe: 0.709 ± 0.745
2.128AlaGly: 2.128 ± 0.902
2.128AlaHis: 2.128 ± 1.001
4.255AlaIle: 4.255 ± 1.362
3.546AlaLys: 3.546 ± 1.525
7.801AlaLeu: 7.801 ± 6.059
2.128AlaMet: 2.128 ± 2.178
1.418AlaAsn: 1.418 ± 0.514
2.128AlaPro: 2.128 ± 1.038
0.709AlaGln: 0.709 ± 0.6
4.255AlaArg: 4.255 ± 1.368
2.128AlaSer: 2.128 ± 0.716
4.255AlaThr: 4.255 ± 2.364
8.511AlaVal: 8.511 ± 1.933
2.128AlaTrp: 2.128 ± 0.628
2.128AlaTyr: 2.128 ± 1.038
0.0AlaXaa: 0.0 ± 0.0
Cys
2.837CysAla: 2.837 ± 0.675
1.418CysCys: 1.418 ± 1.49
0.709CysAsp: 0.709 ± 0.6
1.418CysGlu: 1.418 ± 0.736
0.709CysPhe: 0.709 ± 0.745
0.709CysGly: 0.709 ± 0.6
0.0CysHis: 0.0 ± 0.0
1.418CysIle: 1.418 ± 0.825
2.837CysLys: 2.837 ± 0.675
1.418CysLeu: 1.418 ± 1.49
1.418CysMet: 1.418 ± 0.736
2.128CysAsn: 2.128 ± 0.932
1.418CysPro: 1.418 ± 0.514
0.709CysGln: 0.709 ± 0.412
0.0CysArg: 0.0 ± 0.0
1.418CysSer: 1.418 ± 1.2
1.418CysThr: 1.418 ± 0.825
1.418CysVal: 1.418 ± 0.821
0.0CysTrp: 0.0 ± 0.0
4.255CysTyr: 4.255 ± 2.846
0.0CysXaa: 0.0 ± 0.0
Asp
3.546AspAla: 3.546 ± 0.494
0.709AspCys: 0.709 ± 0.745
4.965AspAsp: 4.965 ± 2.21
4.255AspGlu: 4.255 ± 1.316
3.546AspPhe: 3.546 ± 1.595
6.383AspGly: 6.383 ± 1.755
1.418AspHis: 1.418 ± 0.514
1.418AspIle: 1.418 ± 1.001
4.965AspLys: 4.965 ± 1.513
3.546AspLeu: 3.546 ± 1.519
0.0AspMet: 0.0 ± 0.0
2.128AspAsn: 2.128 ± 0.713
3.546AspPro: 3.546 ± 1.172
1.418AspGln: 1.418 ± 0.825
1.418AspArg: 1.418 ± 0.736
2.837AspSer: 2.837 ± 0.603
1.418AspThr: 1.418 ± 0.514
3.546AspVal: 3.546 ± 1.42
0.709AspTrp: 0.709 ± 0.412
1.418AspTyr: 1.418 ± 0.834
0.0AspXaa: 0.0 ± 0.0
Glu
8.511GluAla: 8.511 ± 7.189
1.418GluCys: 1.418 ± 0.825
2.128GluAsp: 2.128 ± 0.713
5.674GluGlu: 5.674 ± 1.478
2.837GluPhe: 2.837 ± 1.473
4.965GluGly: 4.965 ± 1.881
0.709GluHis: 0.709 ± 0.412
0.0GluIle: 0.0 ± 0.0
6.383GluLys: 6.383 ± 1.566
10.638GluLeu: 10.638 ± 3.762
1.418GluMet: 1.418 ± 0.514
5.674GluAsn: 5.674 ± 1.206
1.418GluPro: 1.418 ± 0.514
0.709GluGln: 0.709 ± 0.959
0.709GluArg: 0.709 ± 0.412
2.837GluSer: 2.837 ± 0.759
2.128GluThr: 2.128 ± 0.628
2.128GluVal: 2.128 ± 1.801
0.0GluTrp: 0.0 ± 0.0
2.128GluTyr: 2.128 ± 0.932
0.0GluXaa: 0.0 ± 0.0
Phe
4.965PheAla: 4.965 ± 1.399
2.837PheCys: 2.837 ± 2.149
0.0PheAsp: 0.0 ± 0.0
2.128PheGlu: 2.128 ± 1.237
1.418PhePhe: 1.418 ± 0.514
2.837PheGly: 2.837 ± 0.984
2.128PheHis: 2.128 ± 1.001
2.128PheIle: 2.128 ± 0.902
2.837PheLys: 2.837 ± 1.649
4.255PheLeu: 4.255 ± 1.264
1.418PheMet: 1.418 ± 0.736
2.128PheAsn: 2.128 ± 1.117
2.837PhePro: 2.837 ± 0.967
2.128PheGln: 2.128 ± 1.001
1.418PheArg: 1.418 ± 0.514
2.128PheSer: 2.128 ± 0.902
1.418PheThr: 1.418 ± 0.821
2.128PheVal: 2.128 ± 0.902
0.709PheTrp: 0.709 ± 0.745
2.837PheTyr: 2.837 ± 1.028
0.0PheXaa: 0.0 ± 0.0
Gly
3.546GlyAla: 3.546 ± 2.314
0.709GlyCys: 0.709 ± 0.412
4.965GlyAsp: 4.965 ± 1.537
4.255GlyGlu: 4.255 ± 2.07
3.546GlyPhe: 3.546 ± 1.611
5.674GlyGly: 5.674 ± 1.579
0.709GlyHis: 0.709 ± 0.412
4.965GlyIle: 4.965 ± 2.304
3.546GlyLys: 3.546 ± 0.925
6.383GlyLeu: 6.383 ± 2.521
0.0GlyMet: 0.0 ± 0.0
3.546GlyAsn: 3.546 ± 1.403
5.674GlyPro: 5.674 ± 1.349
5.674GlyGln: 5.674 ± 1.132
1.418GlyArg: 1.418 ± 0.834
1.418GlySer: 1.418 ± 0.834
1.418GlyThr: 1.418 ± 1.2
7.801GlyVal: 7.801 ± 0.821
0.0GlyTrp: 0.0 ± 0.0
1.418GlyTyr: 1.418 ± 1.2
0.0GlyXaa: 0.0 ± 0.0
His
0.709HisAla: 0.709 ± 0.412
2.128HisCys: 2.128 ± 0.932
1.418HisAsp: 1.418 ± 0.834
0.0HisGlu: 0.0 ± 0.0
1.418HisPhe: 1.418 ± 1.2
0.0HisGly: 0.0 ± 0.0
0.709HisHis: 0.709 ± 0.959
0.0HisIle: 0.0 ± 0.0
0.0HisLys: 0.0 ± 0.0
2.128HisLeu: 2.128 ± 1.038
0.709HisMet: 0.709 ± 0.635
1.418HisAsn: 1.418 ± 0.736
2.128HisPro: 2.128 ± 0.932
1.418HisGln: 1.418 ± 0.834
1.418HisArg: 1.418 ± 0.736
0.709HisSer: 0.709 ± 0.959
0.0HisThr: 0.0 ± 0.0
1.418HisVal: 1.418 ± 0.825
0.709HisTrp: 0.709 ± 0.745
1.418HisTyr: 1.418 ± 0.825
0.0HisXaa: 0.0 ± 0.0
Ile
2.128IleAla: 2.128 ± 1.23
1.418IleCys: 1.418 ± 0.514
2.837IleAsp: 2.837 ± 1.649
2.128IleGlu: 2.128 ± 1.344
0.0IlePhe: 0.0 ± 0.0
1.418IleGly: 1.418 ± 1.001
0.0IleHis: 0.0 ± 0.0
2.128IleIle: 2.128 ± 0.902
1.418IleLys: 1.418 ± 0.825
4.255IleLeu: 4.255 ± 1.35
2.128IleMet: 2.128 ± 1.237
2.837IleAsn: 2.837 ± 0.967
5.674IlePro: 5.674 ± 1.772
0.709IleGln: 0.709 ± 0.412
1.418IleArg: 1.418 ± 0.834
2.837IleSer: 2.837 ± 3.835
4.255IleThr: 4.255 ± 0.747
2.837IleVal: 2.837 ± 1.028
1.418IleTrp: 1.418 ± 1.918
4.255IleTyr: 4.255 ± 1.316
0.0IleXaa: 0.0 ± 0.0
Lys
4.965LysAla: 4.965 ± 2.024
2.128LysCys: 2.128 ± 0.628
0.709LysAsp: 0.709 ± 0.6
3.546LysGlu: 3.546 ± 2.14
2.837LysPhe: 2.837 ± 1.239
5.674LysGly: 5.674 ± 1.772
1.418LysHis: 1.418 ± 0.825
2.837LysIle: 2.837 ± 1.473
7.801LysLys: 7.801 ± 2.693
7.092LysLeu: 7.092 ± 1.85
6.383LysMet: 6.383 ± 1.813
2.837LysAsn: 2.837 ± 1.028
4.255LysPro: 4.255 ± 1.811
2.128LysGln: 2.128 ± 0.932
5.674LysArg: 5.674 ± 1.478
2.837LysSer: 2.837 ± 1.045
6.383LysThr: 6.383 ± 3.018
2.837LysVal: 2.837 ± 1.473
0.0LysTrp: 0.0 ± 0.0
1.418LysTyr: 1.418 ± 0.736
0.0LysXaa: 0.0 ± 0.0
Leu
5.674LeuAla: 5.674 ± 3.408
2.128LeuCys: 2.128 ± 0.628
4.965LeuAsp: 4.965 ± 1.74
5.674LeuGlu: 5.674 ± 1.195
7.092LeuPhe: 7.092 ± 2.005
2.837LeuGly: 2.837 ± 0.967
2.128LeuHis: 2.128 ± 0.713
4.965LeuIle: 4.965 ± 1.74
4.255LeuLys: 4.255 ± 1.864
9.929LeuLeu: 9.929 ± 2.058
1.418LeuMet: 1.418 ± 0.834
6.383LeuAsn: 6.383 ± 1.661
6.383LeuPro: 6.383 ± 1.305
7.092LeuGln: 7.092 ± 0.674
2.128LeuArg: 2.128 ± 0.716
4.965LeuSer: 4.965 ± 1.274
6.383LeuThr: 6.383 ± 1.569
5.674LeuVal: 5.674 ± 2.429
2.128LeuTrp: 2.128 ± 1.423
2.837LeuTyr: 2.837 ± 1.045
0.0LeuXaa: 0.0 ± 0.0
Met
2.128MetAla: 2.128 ± 0.716
0.709MetCys: 0.709 ± 0.745
2.837MetAsp: 2.837 ± 1.473
0.709MetGlu: 0.709 ± 0.412
0.709MetPhe: 0.709 ± 0.412
2.128MetGly: 2.128 ± 0.716
0.709MetHis: 0.709 ± 0.745
1.418MetIle: 1.418 ± 0.736
3.546MetLys: 3.546 ± 1.629
2.128MetLeu: 2.128 ± 0.902
2.837MetMet: 2.837 ± 1.188
3.546MetAsn: 3.546 ± 1.629
0.709MetPro: 0.709 ± 0.6
2.128MetGln: 2.128 ± 1.038
0.0MetArg: 0.0 ± 0.0
2.128MetSer: 2.128 ± 0.716
2.128MetThr: 2.128 ± 1.23
0.709MetVal: 0.709 ± 0.412
0.709MetTrp: 0.709 ± 0.6
0.709MetTyr: 0.709 ± 0.6
0.0MetXaa: 0.0 ± 0.0
Asn
2.128AsnAla: 2.128 ± 0.932
2.128AsnCys: 2.128 ± 0.932
0.709AsnAsp: 0.709 ± 0.6
6.383AsnGlu: 6.383 ± 0.907
1.418AsnPhe: 1.418 ± 0.825
2.128AsnGly: 2.128 ± 1.801
0.0AsnHis: 0.0 ± 0.0
2.128AsnIle: 2.128 ± 1.237
5.674AsnLys: 5.674 ± 1.785
7.801AsnLeu: 7.801 ± 1.938
0.709AsnMet: 0.709 ± 0.6
2.128AsnAsn: 2.128 ± 1.038
3.546AsnPro: 3.546 ± 1.504
2.837AsnGln: 2.837 ± 1.025
0.709AsnArg: 0.709 ± 0.6
2.128AsnSer: 2.128 ± 1.75
2.837AsnThr: 2.837 ± 1.025
3.546AsnVal: 3.546 ± 0.796
0.709AsnTrp: 0.709 ± 0.959
2.128AsnTyr: 2.128 ± 1.001
0.0AsnXaa: 0.0 ± 0.0
Pro
4.255ProAla: 4.255 ± 0.947
1.418ProCys: 1.418 ± 0.736
7.092ProAsp: 7.092 ± 1.562
2.837ProGlu: 2.837 ± 0.603
2.128ProPhe: 2.128 ± 1.237
6.383ProGly: 6.383 ± 0.559
0.709ProHis: 0.709 ± 0.745
2.128ProIle: 2.128 ± 1.038
6.383ProLys: 6.383 ± 1.755
3.546ProLeu: 3.546 ± 1.172
2.128ProMet: 2.128 ± 0.628
1.418ProAsn: 1.418 ± 0.514
3.546ProPro: 3.546 ± 1.42
1.418ProGln: 1.418 ± 0.834
1.418ProArg: 1.418 ± 1.2
3.546ProSer: 3.546 ± 0.744
0.709ProThr: 0.709 ± 0.6
4.965ProVal: 4.965 ± 2.647
0.0ProTrp: 0.0 ± 0.0
0.709ProTyr: 0.709 ± 0.6
0.0ProXaa: 0.0 ± 0.0
Gln
3.546GlnAla: 3.546 ± 1.434
0.0GlnCys: 0.0 ± 0.0
4.255GlnAsp: 4.255 ± 1.35
1.418GlnGlu: 1.418 ± 0.825
2.837GlnPhe: 2.837 ± 1.028
2.837GlnGly: 2.837 ± 1.617
1.418GlnHis: 1.418 ± 1.186
5.674GlnIle: 5.674 ± 0.309
2.837GlnLys: 2.837 ± 1.239
0.709GlnLeu: 0.709 ± 0.412
1.418GlnMet: 1.418 ± 0.825
1.418GlnAsn: 1.418 ± 0.834
2.128GlnPro: 2.128 ± 1.038
0.709GlnGln: 0.709 ± 0.412
0.709GlnArg: 0.709 ± 0.412
3.546GlnSer: 3.546 ± 2.062
2.128GlnThr: 2.128 ± 1.117
3.546GlnVal: 3.546 ± 1.519
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
0.709ArgAla: 0.709 ± 0.959
0.709ArgCys: 0.709 ± 0.745
4.965ArgAsp: 4.965 ± 1.64
1.418ArgGlu: 1.418 ± 0.834
2.837ArgPhe: 2.837 ± 1.239
1.418ArgGly: 1.418 ± 0.514
0.0ArgHis: 0.0 ± 0.0
3.546ArgIle: 3.546 ± 0.934
2.128ArgLys: 2.128 ± 1.038
1.418ArgLeu: 1.418 ± 0.834
2.837ArgMet: 2.837 ± 0.651
1.418ArgAsn: 1.418 ± 0.514
1.418ArgPro: 1.418 ± 0.834
0.0ArgGln: 0.0 ± 0.0
0.709ArgArg: 0.709 ± 0.412
0.709ArgSer: 0.709 ± 0.412
0.709ArgThr: 0.709 ± 0.6
1.418ArgVal: 1.418 ± 0.834
0.709ArgTrp: 0.709 ± 0.745
3.546ArgTyr: 3.546 ± 1.519
0.0ArgXaa: 0.0 ± 0.0
Ser
4.255SerAla: 4.255 ± 3.499
2.128SerCys: 2.128 ± 1.801
2.837SerAsp: 2.837 ± 1.649
1.418SerGlu: 1.418 ± 0.736
4.965SerPhe: 4.965 ± 1.219
2.837SerGly: 2.837 ± 1.127
0.709SerHis: 0.709 ± 0.412
2.128SerIle: 2.128 ± 1.866
1.418SerLys: 1.418 ± 1.2
7.092SerLeu: 7.092 ± 1.956
2.128SerMet: 2.128 ± 1.866
2.128SerAsn: 2.128 ± 1.237
2.837SerPro: 2.837 ± 1.045
2.128SerGln: 2.128 ± 1.237
1.418SerArg: 1.418 ± 0.736
6.383SerSer: 6.383 ± 2.55
4.255SerThr: 4.255 ± 1.275
3.546SerVal: 3.546 ± 1.691
0.709SerTrp: 0.709 ± 0.959
0.709SerTyr: 0.709 ± 0.412
0.0SerXaa: 0.0 ± 0.0
Thr
2.128ThrAla: 2.128 ± 0.716
0.709ThrCys: 0.709 ± 0.6
0.709ThrAsp: 0.709 ± 0.6
3.546ThrGlu: 3.546 ± 0.925
1.418ThrPhe: 1.418 ± 0.834
5.674ThrGly: 5.674 ± 3.524
2.128ThrHis: 2.128 ± 0.713
1.418ThrIle: 1.418 ± 0.514
3.546ThrLys: 3.546 ± 1.525
6.383ThrLeu: 6.383 ± 1.554
0.709ThrMet: 0.709 ± 0.412
1.418ThrAsn: 1.418 ± 1.001
2.128ThrPro: 2.128 ± 0.628
3.546ThrGln: 3.546 ± 1.172
3.546ThrArg: 3.546 ± 0.494
2.837ThrSer: 2.837 ± 1.617
5.674ThrThr: 5.674 ± 1.87
3.546ThrVal: 3.546 ± 0.796
0.0ThrTrp: 0.0 ± 0.0
2.128ThrTyr: 2.128 ± 1.038
0.0ThrXaa: 0.0 ± 0.0
Val
3.546ValAla: 3.546 ± 1.434
2.837ValCys: 2.837 ± 1.473
3.546ValAsp: 3.546 ± 1.172
5.674ValGlu: 5.674 ± 2.108
1.418ValPhe: 1.418 ± 0.825
5.674ValGly: 5.674 ± 1.447
0.709ValHis: 0.709 ± 0.6
2.128ValIle: 2.128 ± 0.713
5.674ValLys: 5.674 ± 1.366
4.965ValLeu: 4.965 ± 2.65
0.0ValMet: 0.0 ± 0.0
4.965ValAsn: 4.965 ± 1.258
2.128ValPro: 2.128 ± 0.716
2.837ValGln: 2.837 ± 0.603
2.837ValArg: 2.837 ± 2.002
6.383ValSer: 6.383 ± 1.317
3.546ValThr: 3.546 ± 1.519
4.965ValVal: 4.965 ± 1.412
1.418ValTrp: 1.418 ± 0.821
2.837ValTyr: 2.837 ± 1.279
0.0ValXaa: 0.0 ± 0.0
Trp
0.709TrpAla: 0.709 ± 0.745
0.0TrpCys: 0.0 ± 0.0
1.418TrpAsp: 1.418 ± 1.001
1.418TrpGlu: 1.418 ± 0.821
1.418TrpPhe: 1.418 ± 1.49
2.128TrpGly: 2.128 ± 1.734
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.709TrpLys: 0.709 ± 0.412
0.709TrpLeu: 0.709 ± 0.959
0.0TrpMet: 0.0 ± 0.0
0.709TrpAsn: 0.709 ± 0.412
0.0TrpPro: 0.0 ± 0.0
1.418TrpGln: 1.418 ± 0.736
0.709TrpArg: 0.709 ± 0.959
0.709TrpSer: 0.709 ± 0.6
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.709TrpTrp: 0.709 ± 0.745
0.709TrpTyr: 0.709 ± 0.412
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.709TyrAla: 0.709 ± 0.412
0.0TyrCys: 0.0 ± 0.0
1.418TyrAsp: 1.418 ± 1.001
1.418TyrGlu: 1.418 ± 0.821
1.418TyrPhe: 1.418 ± 1.2
2.837TyrGly: 2.837 ± 1.279
2.128TyrHis: 2.128 ± 0.932
1.418TyrIle: 1.418 ± 1.186
4.255TyrLys: 4.255 ± 1.864
2.837TyrLeu: 2.837 ± 0.675
2.128TyrMet: 2.128 ± 1.237
2.128TyrAsn: 2.128 ± 1.038
2.837TyrPro: 2.837 ± 1.753
1.418TyrGln: 1.418 ± 0.825
0.709TyrArg: 0.709 ± 0.745
3.546TyrSer: 3.546 ± 1.172
2.128TyrThr: 2.128 ± 0.713
3.546TyrVal: 3.546 ± 0.934
0.709TyrTrp: 0.709 ± 0.412
0.709TyrTyr: 0.709 ± 0.959
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1411 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski