Amino acid dipepetide frequency for Falsochrobactrum shanghaiense

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	14.525AlaAla: 14.525 ± 0.171	0.909AlaCys: 0.909 ± 0.03	6.389AlaAsp: 6.389 ± 0.083	7.185AlaGlu: 7.185 ± 0.104	4.439AlaPhe: 4.439 ± 0.065	9.564AlaGly: 9.564 ± 0.121	2.208AlaHis: 2.208 ± 0.042	7.06AlaIle: 7.06 ± 0.094	4.125AlaLys: 4.125 ± 0.07	12.43AlaLeu: 12.43 ± 0.139	3.406AlaMet: 3.406 ± 0.057	3.12AlaAsn: 3.12 ± 0.053	4.725AlaPro: 4.725 ± 0.084	4.237AlaGln: 4.237 ± 0.067	7.827AlaArg: 7.827 ± 0.092	6.661AlaSer: 6.661 ± 0.096	5.365AlaThr: 5.365 ± 0.074	7.913AlaVal: 7.913 ± 0.089	1.22AlaTrp: 1.22 ± 0.032	2.635AlaTyr: 2.635 ± 0.051	0.0AlaXaa: 0.0 ± 0.0
Cys	0.874CysAla: 0.874 ± 0.029	0.108CysCys: 0.108 ± 0.011	0.514CysAsp: 0.514 ± 0.022	0.415CysGlu: 0.415 ± 0.016	0.346CysPhe: 0.346 ± 0.017	0.842CysGly: 0.842 ± 0.028	0.238CysHis: 0.238 ± 0.018	0.461CysIle: 0.461 ± 0.02	0.219CysLys: 0.219 ± 0.014	0.698CysLeu: 0.698 ± 0.025	0.18CysMet: 0.18 ± 0.013	0.228CysAsn: 0.228 ± 0.014	0.417CysPro: 0.417 ± 0.02	0.228CysGln: 0.228 ± 0.012	0.523CysArg: 0.523 ± 0.024	0.452CysSer: 0.452 ± 0.021	0.378CysThr: 0.378 ± 0.021	0.548CysVal: 0.548 ± 0.025	0.107CysTrp: 0.107 ± 0.009	0.181CysTyr: 0.181 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	6.379AspAla: 6.379 ± 0.093	0.469AspCys: 0.469 ± 0.021	3.137AspAsp: 3.137 ± 0.061	3.892AspGlu: 3.892 ± 0.07	2.296AspPhe: 2.296 ± 0.041	4.815AspGly: 4.815 ± 0.076	1.283AspHis: 1.283 ± 0.034	3.504AspIle: 3.504 ± 0.065	2.038AspLys: 2.038 ± 0.043	5.404AspLeu: 5.404 ± 0.065	1.619AspMet: 1.619 ± 0.04	1.667AspAsn: 1.667 ± 0.037	3.05AspPro: 3.05 ± 0.049	1.695AspGln: 1.695 ± 0.042	3.99AspArg: 3.99 ± 0.065	2.215AspSer: 2.215 ± 0.044	2.494AspThr: 2.494 ± 0.047	3.929AspVal: 3.929 ± 0.057	0.923AspTrp: 0.923 ± 0.031	1.645AspTyr: 1.645 ± 0.04	0.0AspXaa: 0.0 ± 0.0
Glu	7.544GluAla: 7.544 ± 0.095	0.368GluCys: 0.368 ± 0.018	2.977GluAsp: 2.977 ± 0.062	3.845GluGlu: 3.845 ± 0.07	1.847GluPhe: 1.847 ± 0.043	4.488GluGly: 4.488 ± 0.075	1.262GluHis: 1.262 ± 0.033	3.934GluIle: 3.934 ± 0.071	3.295GluLys: 3.295 ± 0.06	5.524GluLeu: 5.524 ± 0.076	1.656GluMet: 1.656 ± 0.039	2.209GluAsn: 2.209 ± 0.051	2.689GluPro: 2.689 ± 0.058	2.329GluGln: 2.329 ± 0.048	4.856GluArg: 4.856 ± 0.071	2.547GluSer: 2.547 ± 0.044	3.575GluThr: 3.575 ± 0.067	3.696GluVal: 3.696 ± 0.075	0.719GluTrp: 0.719 ± 0.026	1.217GluTyr: 1.217 ± 0.035	0.0GluXaa: 0.0 ± 0.0
Phe	4.514PheAla: 4.514 ± 0.067	0.394PheCys: 0.394 ± 0.019	2.725PheAsp: 2.725 ± 0.048	2.229PheGlu: 2.229 ± 0.045	1.589PhePhe: 1.589 ± 0.045	3.64PheGly: 3.64 ± 0.057	0.815PheHis: 0.815 ± 0.029	2.169PheIle: 2.169 ± 0.047	1.154PheLys: 1.154 ± 0.034	3.49PheLeu: 3.49 ± 0.069	0.922PheMet: 0.922 ± 0.029	1.236PheAsn: 1.236 ± 0.036	1.608PhePro: 1.608 ± 0.04	1.098PheGln: 1.098 ± 0.033	2.286PheArg: 2.286 ± 0.043	2.633PheSer: 2.633 ± 0.048	2.067PheThr: 2.067 ± 0.046	2.753PheVal: 2.753 ± 0.055	0.561PheTrp: 0.561 ± 0.025	0.979PheTyr: 0.979 ± 0.029	0.0PheXaa: 0.0 ± 0.0
Gly	8.24GlyAla: 8.24 ± 0.106	0.751GlyCys: 0.751 ± 0.026	4.149GlyAsp: 4.149 ± 0.061	4.888GlyGlu: 4.888 ± 0.073	3.738GlyPhe: 3.738 ± 0.072	6.777GlyGly: 6.777 ± 0.131	1.803GlyHis: 1.803 ± 0.038	5.176GlyIle: 5.176 ± 0.074	3.849GlyLys: 3.849 ± 0.069	8.398GlyLeu: 8.398 ± 0.106	2.31GlyMet: 2.31 ± 0.052	2.551GlyAsn: 2.551 ± 0.062	2.965GlyPro: 2.965 ± 0.049	2.816GlyGln: 2.816 ± 0.058	5.447GlyArg: 5.447 ± 0.073	4.692GlySer: 4.692 ± 0.084	4.357GlyThr: 4.357 ± 0.116	5.721GlyVal: 5.721 ± 0.081	1.256GlyTrp: 1.256 ± 0.032	2.333GlyTyr: 2.333 ± 0.049	0.0GlyXaa: 0.0 ± 0.0
His	2.085HisAla: 2.085 ± 0.051	0.214HisCys: 0.214 ± 0.013	1.282HisAsp: 1.282 ± 0.039	1.223HisGlu: 1.223 ± 0.036	0.884HisPhe: 0.884 ± 0.029	1.909HisGly: 1.909 ± 0.045	0.561HisHis: 0.561 ± 0.027	1.242HisIle: 1.242 ± 0.036	0.635HisLys: 0.635 ± 0.023	1.987HisLeu: 1.987 ± 0.047	0.58HisMet: 0.58 ± 0.022	0.576HisAsn: 0.576 ± 0.025	1.226HisPro: 1.226 ± 0.039	0.588HisGln: 0.588 ± 0.021	1.354HisArg: 1.354 ± 0.039	1.007HisSer: 1.007 ± 0.031	0.806HisThr: 0.806 ± 0.028	1.448HisVal: 1.448 ± 0.041	0.294HisTrp: 0.294 ± 0.017	0.596HisTyr: 0.596 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	8.117IleAla: 8.117 ± 0.092	0.577IleCys: 0.577 ± 0.024	3.928IleAsp: 3.928 ± 0.065	4.1IleGlu: 4.1 ± 0.059	2.14IlePhe: 2.14 ± 0.046	5.393IleGly: 5.393 ± 0.083	1.123IleHis: 1.123 ± 0.034	3.461IleIle: 3.461 ± 0.067	1.791IleLys: 1.791 ± 0.041	5.232IleLeu: 5.232 ± 0.074	1.337IleMet: 1.337 ± 0.039	1.859IleAsn: 1.859 ± 0.047	2.456IlePro: 2.456 ± 0.046	1.392IleGln: 1.392 ± 0.033	3.714IleArg: 3.714 ± 0.061	3.602IleSer: 3.602 ± 0.062	2.973IleThr: 2.973 ± 0.052	4.609IleVal: 4.609 ± 0.074	0.666IleTrp: 0.666 ± 0.028	1.384IleTyr: 1.384 ± 0.034	0.0IleXaa: 0.0 ± 0.0
Lys	4.808LysAla: 4.808 ± 0.082	0.185LysCys: 0.185 ± 0.011	2.013LysAsp: 2.013 ± 0.049	2.043LysGlu: 2.043 ± 0.049	1.076LysPhe: 1.076 ± 0.035	3.044LysGly: 3.044 ± 0.05	0.692LysHis: 0.692 ± 0.026	2.218LysIle: 2.218 ± 0.049	1.767LysLys: 1.767 ± 0.043	3.867LysLeu: 3.867 ± 0.071	0.995LysMet: 0.995 ± 0.028	1.238LysAsn: 1.238 ± 0.036	2.355LysPro: 2.355 ± 0.046	1.272LysGln: 1.272 ± 0.036	2.719LysArg: 2.719 ± 0.048	2.374LysSer: 2.374 ± 0.047	2.235LysThr: 2.235 ± 0.048	2.465LysVal: 2.465 ± 0.05	0.399LysTrp: 0.399 ± 0.019	0.774LysTyr: 0.774 ± 0.027	0.0LysXaa: 0.0 ± 0.0
Leu	12.336LeuAla: 12.336 ± 0.123	0.858LeuCys: 0.858 ± 0.028	5.844LeuAsp: 5.844 ± 0.078	5.737LeuGlu: 5.737 ± 0.072	3.833LeuPhe: 3.833 ± 0.072	7.732LeuGly: 7.732 ± 0.1	1.797LeuHis: 1.797 ± 0.042	5.494LeuIle: 5.494 ± 0.086	4.029LeuLys: 4.029 ± 0.065	9.263LeuLeu: 9.263 ± 0.121	2.431LeuMet: 2.431 ± 0.047	2.861LeuAsn: 2.861 ± 0.054	5.2LeuPro: 5.2 ± 0.062	2.847LeuGln: 2.847 ± 0.052	6.39LeuArg: 6.39 ± 0.077	6.679LeuSer: 6.679 ± 0.068	5.297LeuThr: 5.297 ± 0.08	7.049LeuVal: 7.049 ± 0.079	1.012LeuTrp: 1.012 ± 0.031	2.212LeuTyr: 2.212 ± 0.046	0.0LeuXaa: 0.0 ± 0.0
Met	3.014MetAla: 3.014 ± 0.048	0.159MetCys: 0.159 ± 0.012	1.175MetAsp: 1.175 ± 0.033	1.375MetGlu: 1.375 ± 0.031	0.746MetPhe: 0.746 ± 0.026	1.926MetGly: 1.926 ± 0.047	0.487MetHis: 0.487 ± 0.022	1.597MetIle: 1.597 ± 0.043	1.206MetLys: 1.206 ± 0.036	2.633MetLeu: 2.633 ± 0.052	0.709MetMet: 0.709 ± 0.03	0.946MetAsn: 0.946 ± 0.026	1.505MetPro: 1.505 ± 0.036	1.023MetGln: 1.023 ± 0.032	1.987MetArg: 1.987 ± 0.042	1.822MetSer: 1.822 ± 0.035	1.762MetThr: 1.762 ± 0.038	1.723MetVal: 1.723 ± 0.045	0.238MetTrp: 0.238 ± 0.016	0.297MetTyr: 0.297 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	3.528AsnAla: 3.528 ± 0.06	0.254AsnCys: 0.254 ± 0.014	1.642AsnAsp: 1.642 ± 0.034	1.668AsnGlu: 1.668 ± 0.038	1.071AsnPhe: 1.071 ± 0.036	2.758AsnGly: 2.758 ± 0.075	0.625AsnHis: 0.625 ± 0.021	1.962AsnIle: 1.962 ± 0.047	0.983AsnLys: 0.983 ± 0.034	2.877AsnLeu: 2.877 ± 0.058	0.82AsnMet: 0.82 ± 0.025	0.946AsnAsn: 0.946 ± 0.032	1.962AsnPro: 1.962 ± 0.049	0.938AsnGln: 0.938 ± 0.034	2.112AsnArg: 2.112 ± 0.043	1.642AsnSer: 1.642 ± 0.042	1.441AsnThr: 1.441 ± 0.038	2.11AsnVal: 2.11 ± 0.041	0.497AsnTrp: 0.497 ± 0.023	0.818AsnTyr: 0.818 ± 0.03	0.0AsnXaa: 0.0 ± 0.0
Pro	5.393ProAla: 5.393 ± 0.082	0.306ProCys: 0.306 ± 0.019	3.363ProAsp: 3.363 ± 0.051	3.564ProGlu: 3.564 ± 0.05	2.017ProPhe: 2.017 ± 0.037	3.785ProGly: 3.785 ± 0.073	1.085ProHis: 1.085 ± 0.03	2.337ProIle: 2.337 ± 0.045	1.653ProLys: 1.653 ± 0.038	4.487ProLeu: 4.487 ± 0.063	1.113ProMet: 1.113 ± 0.03	1.372ProAsn: 1.372 ± 0.038	1.952ProPro: 1.952 ± 0.049	1.944ProGln: 1.944 ± 0.042	2.501ProArg: 2.501 ± 0.056	2.676ProSer: 2.676 ± 0.057	2.184ProThr: 2.184 ± 0.049	4.183ProVal: 4.183 ± 0.065	0.606ProTrp: 0.606 ± 0.026	1.193ProTyr: 1.193 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	4.073GlnAla: 4.073 ± 0.061	0.216GlnCys: 0.216 ± 0.016	1.526GlnAsp: 1.526 ± 0.037	1.824GlnGlu: 1.824 ± 0.046	1.201GlnPhe: 1.201 ± 0.034	2.341GlnGly: 2.341 ± 0.048	0.656GlnHis: 0.656 ± 0.026	2.133GlnIle: 2.133 ± 0.041	1.506GlnLys: 1.506 ± 0.041	3.07GlnLeu: 3.07 ± 0.063	0.96GlnMet: 0.96 ± 0.03	1.104GlnAsn: 1.104 ± 0.03	1.755GlnPro: 1.755 ± 0.043	1.38GlnGln: 1.38 ± 0.043	2.4GlnArg: 2.4 ± 0.049	2.045GlnSer: 2.045 ± 0.043	1.747GlnThr: 1.747 ± 0.046	2.116GlnVal: 2.116 ± 0.051	0.429GlnTrp: 0.429 ± 0.02	0.727GlnTyr: 0.727 ± 0.028	0.0GlnXaa: 0.0 ± 0.0
Arg	6.708ArgAla: 6.708 ± 0.081	0.439ArgCys: 0.439 ± 0.022	3.769ArgAsp: 3.769 ± 0.059	4.249ArgGlu: 4.249 ± 0.072	2.9ArgPhe: 2.9 ± 0.047	4.367ArgGly: 4.367 ± 0.065	1.612ArgHis: 1.612 ± 0.038	4.368ArgIle: 4.368 ± 0.055	2.823ArgLys: 2.823 ± 0.057	7.347ArgLeu: 7.347 ± 0.087	1.894ArgMet: 1.894 ± 0.049	2.257ArgAsn: 2.257 ± 0.046	3.043ArgPro: 3.043 ± 0.057	2.689ArgGln: 2.689 ± 0.052	4.854ArgArg: 4.854 ± 0.088	3.667ArgSer: 3.667 ± 0.051	3.123ArgThr: 3.123 ± 0.049	4.289ArgVal: 4.289 ± 0.061	0.841ArgTrp: 0.841 ± 0.027	1.704ArgTyr: 1.704 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	6.42SerAla: 6.42 ± 0.088	0.422SerCys: 0.422 ± 0.023	3.22SerAsp: 3.22 ± 0.059	3.152SerGlu: 3.152 ± 0.059	2.612SerPhe: 2.612 ± 0.051	5.908SerGly: 5.908 ± 0.112	1.15SerHis: 1.15 ± 0.033	3.332SerIle: 3.332 ± 0.058	1.947SerLys: 1.947 ± 0.046	5.71SerLeu: 5.71 ± 0.077	1.473SerMet: 1.473 ± 0.039	1.662SerAsn: 1.662 ± 0.036	2.632SerPro: 2.632 ± 0.045	1.779SerGln: 1.779 ± 0.04	3.708SerArg: 3.708 ± 0.058	3.352SerSer: 3.352 ± 0.066	2.754SerThr: 2.754 ± 0.051	4.154SerVal: 4.154 ± 0.061	0.75SerTrp: 0.75 ± 0.03	1.424SerTyr: 1.424 ± 0.039	0.0SerXaa: 0.0 ± 0.0
Thr	5.76ThrAla: 5.76 ± 0.079	0.377ThrCys: 0.377 ± 0.021	2.735ThrAsp: 2.735 ± 0.049	2.569ThrGlu: 2.569 ± 0.049	1.869ThrPhe: 1.869 ± 0.045	4.969ThrGly: 4.969 ± 0.083	1.017ThrHis: 1.017 ± 0.03	3.315ThrIle: 3.315 ± 0.055	1.598ThrLys: 1.598 ± 0.033	5.468ThrLeu: 5.468 ± 0.09	1.186ThrMet: 1.186 ± 0.032	1.393ThrAsn: 1.393 ± 0.04	2.955ThrPro: 2.955 ± 0.055	1.538ThrGln: 1.538 ± 0.033	3.076ThrArg: 3.076 ± 0.049	2.858ThrSer: 2.858 ± 0.051	2.655ThrThr: 2.655 ± 0.062	4.118ThrVal: 4.118 ± 0.068	0.549ThrTrp: 0.549 ± 0.021	1.158ThrTyr: 1.158 ± 0.033	0.0ThrXaa: 0.0 ± 0.0
Val	8.032ValAla: 8.032 ± 0.09	0.568ValCys: 0.568 ± 0.021	3.897ValAsp: 3.897 ± 0.065	4.66ValGlu: 4.66 ± 0.073	2.766ValPhe: 2.766 ± 0.058	4.966ValGly: 4.966 ± 0.079	1.3ValHis: 1.3 ± 0.034	4.292ValIle: 4.292 ± 0.067	2.616ValLys: 2.616 ± 0.052	7.131ValLeu: 7.131 ± 0.094	1.886ValMet: 1.886 ± 0.045	2.234ValAsn: 2.234 ± 0.051	3.403ValPro: 3.403 ± 0.062	2.039ValGln: 2.039 ± 0.041	4.481ValArg: 4.481 ± 0.069	4.469ValSer: 4.469 ± 0.073	4.149ValThr: 4.149 ± 0.066	5.253ValVal: 5.253 ± 0.079	0.82ValTrp: 0.82 ± 0.028	1.493ValTyr: 1.493 ± 0.039	0.0ValXaa: 0.0 ± 0.0
Trp	1.104TrpAla: 1.104 ± 0.036	0.13TrpCys: 0.13 ± 0.011	0.622TrpAsp: 0.622 ± 0.023	0.543TrpGlu: 0.543 ± 0.024	0.493TrpPhe: 0.493 ± 0.022	0.846TrpGly: 0.846 ± 0.03	0.312TrpHis: 0.312 ± 0.02	0.597TrpIle: 0.597 ± 0.02	0.536TrpLys: 0.536 ± 0.022	1.578TrpLeu: 1.578 ± 0.043	0.342TrpMet: 0.342 ± 0.021	0.469TrpAsn: 0.469 ± 0.024	0.641TrpPro: 0.641 ± 0.024	0.586TrpGln: 0.586 ± 0.025	0.981TrpArg: 0.981 ± 0.029	0.788TrpSer: 0.788 ± 0.024	0.644TrpThr: 0.644 ± 0.022	0.753TrpVal: 0.753 ± 0.024	0.198TrpTrp: 0.198 ± 0.015	0.283TrpTyr: 0.283 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.49TyrAla: 2.49 ± 0.05	0.255TyrCys: 0.255 ± 0.017	1.54TyrAsp: 1.54 ± 0.044	1.417TyrGlu: 1.417 ± 0.034	0.999TyrPhe: 0.999 ± 0.03	2.145TyrGly: 2.145 ± 0.044	0.474TyrHis: 0.474 ± 0.022	1.2TyrIle: 1.2 ± 0.034	0.77TyrLys: 0.77 ± 0.028	2.308TyrLeu: 2.308 ± 0.043	0.508TyrMet: 0.508 ± 0.023	0.726TyrAsn: 0.726 ± 0.027	1.175TyrPro: 1.175 ± 0.035	0.79TyrGln: 0.79 ± 0.028	1.736TyrArg: 1.736 ± 0.042	1.377TyrSer: 1.377 ± 0.033	1.155TyrThr: 1.155 ± 0.035	1.626TyrVal: 1.626 ± 0.038	0.36TyrTrp: 0.36 ± 0.018	0.674TyrTyr: 0.674 ± 0.027	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3608 proteins (1107300 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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