Amino acid dipepetide frequency for Human mastadenovirus C

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
14.708AlaAla: 14.708 ± 2.937
1.214AlaCys: 1.214 ± 0.466
2.834AlaAsp: 2.834 ± 0.674
3.913AlaGlu: 3.913 ± 0.983
2.969AlaPhe: 2.969 ± 0.649
4.183AlaGly: 4.183 ± 0.96
1.619AlaHis: 1.619 ± 0.385
4.183AlaIle: 4.183 ± 0.786
1.214AlaLys: 1.214 ± 0.425
8.771AlaLeu: 8.771 ± 1.227
1.214AlaMet: 1.214 ± 0.523
2.969AlaAsn: 2.969 ± 0.861
6.882AlaPro: 6.882 ± 1.415
2.834AlaGln: 2.834 ± 0.553
5.937AlaArg: 5.937 ± 1.127
5.532AlaSer: 5.532 ± 1.011
3.913AlaThr: 3.913 ± 0.774
5.532AlaVal: 5.532 ± 0.797
1.079AlaTrp: 1.079 ± 0.389
1.889AlaTyr: 1.889 ± 0.519
0.0AlaXaa: 0.0 ± 0.0
Cys
1.754CysAla: 1.754 ± 0.564
1.484CysCys: 1.484 ± 0.536
0.405CysAsp: 0.405 ± 0.193
0.81CysGlu: 0.81 ± 0.341
0.405CysPhe: 0.405 ± 0.23
2.024CysGly: 2.024 ± 0.499
1.079CysHis: 1.079 ± 0.496
0.675CysIle: 0.675 ± 0.332
0.81CysLys: 0.81 ± 0.28
1.619CysLeu: 1.619 ± 0.439
0.54CysMet: 0.54 ± 0.255
1.349CysAsn: 1.349 ± 0.437
0.675CysPro: 0.675 ± 0.234
0.135CysGln: 0.135 ± 0.132
1.349CysArg: 1.349 ± 0.398
1.484CysSer: 1.484 ± 0.545
1.079CysThr: 1.079 ± 0.406
1.079CysVal: 1.079 ± 0.412
0.27CysTrp: 0.27 ± 0.186
1.214CysTyr: 1.214 ± 0.484
0.0CysXaa: 0.0 ± 0.0
Asp
3.778AspAla: 3.778 ± 0.919
0.675AspCys: 0.675 ± 0.342
3.508AspAsp: 3.508 ± 0.712
4.588AspGlu: 4.588 ± 0.983
1.754AspPhe: 1.754 ± 0.555
2.969AspGly: 2.969 ± 0.772
1.214AspHis: 1.214 ± 0.452
1.619AspIle: 1.619 ± 0.447
1.619AspLys: 1.619 ± 0.421
5.397AspLeu: 5.397 ± 1.095
2.429AspMet: 2.429 ± 0.671
1.079AspAsn: 1.079 ± 0.309
2.294AspPro: 2.294 ± 0.625
1.484AspGln: 1.484 ± 0.363
2.969AspArg: 2.969 ± 0.857
2.969AspSer: 2.969 ± 0.716
1.619AspThr: 1.619 ± 0.615
3.103AspVal: 3.103 ± 0.575
0.675AspTrp: 0.675 ± 0.316
2.159AspTyr: 2.159 ± 0.438
0.0AspXaa: 0.0 ± 0.0
Glu
5.802GluAla: 5.802 ± 0.946
1.619GluCys: 1.619 ± 0.465
5.532GluAsp: 5.532 ± 0.669
9.85GluGlu: 9.85 ± 1.585
2.024GluPhe: 2.024 ± 0.442
4.183GluGly: 4.183 ± 0.886
1.484GluHis: 1.484 ± 0.45
1.484GluIle: 1.484 ± 0.293
2.159GluLys: 2.159 ± 0.465
5.532GluLeu: 5.532 ± 0.787
1.079GluMet: 1.079 ± 0.344
1.754GluAsn: 1.754 ± 0.479
4.048GluPro: 4.048 ± 1.301
3.913GluGln: 3.913 ± 0.67
5.262GluArg: 5.262 ± 1.044
3.103GluSer: 3.103 ± 0.533
3.643GluThr: 3.643 ± 0.689
4.048GluVal: 4.048 ± 0.659
0.27GluTrp: 0.27 ± 0.168
1.484GluTyr: 1.484 ± 0.49
0.0GluXaa: 0.0 ± 0.0
Phe
2.294PheAla: 2.294 ± 0.527
0.675PheCys: 0.675 ± 0.421
1.484PheAsp: 1.484 ± 0.554
2.159PheGlu: 2.159 ± 0.57
1.079PhePhe: 1.079 ± 0.407
1.214PheGly: 1.214 ± 0.4
0.405PheHis: 0.405 ± 0.234
1.889PheIle: 1.889 ± 0.528
1.079PheLys: 1.079 ± 0.542
2.969PheLeu: 2.969 ± 0.858
1.349PheMet: 1.349 ± 0.479
1.079PheAsn: 1.079 ± 0.293
2.834PhePro: 2.834 ± 0.607
1.484PheGln: 1.484 ± 0.33
2.429PheArg: 2.429 ± 0.435
2.564PheSer: 2.564 ± 0.655
2.564PheThr: 2.564 ± 0.626
2.294PheVal: 2.294 ± 0.521
0.135PheTrp: 0.135 ± 0.142
1.214PheTyr: 1.214 ± 0.417
0.0PheXaa: 0.0 ± 0.0
Gly
4.453GlyAla: 4.453 ± 0.891
1.079GlyCys: 1.079 ± 0.316
2.699GlyAsp: 2.699 ± 0.753
2.969GlyGlu: 2.969 ± 0.567
2.699GlyPhe: 2.699 ± 0.455
6.342GlyGly: 6.342 ± 0.886
2.294GlyHis: 2.294 ± 0.499
3.508GlyIle: 3.508 ± 0.752
1.079GlyLys: 1.079 ± 0.406
4.993GlyLeu: 4.993 ± 0.722
2.159GlyMet: 2.159 ± 0.669
3.103GlyAsn: 3.103 ± 0.92
3.373GlyPro: 3.373 ± 0.612
2.429GlyGln: 2.429 ± 0.537
5.128GlyArg: 5.128 ± 1.024
4.048GlySer: 4.048 ± 0.841
2.564GlyThr: 2.564 ± 0.527
5.128GlyVal: 5.128 ± 1.166
0.135GlyTrp: 0.135 ± 0.143
1.349GlyTyr: 1.349 ± 0.486
0.0GlyXaa: 0.0 ± 0.0
His
1.484HisAla: 1.484 ± 0.365
1.079HisCys: 1.079 ± 0.62
1.079HisAsp: 1.079 ± 0.462
1.079HisGlu: 1.079 ± 0.383
0.675HisPhe: 0.675 ± 0.278
2.159HisGly: 2.159 ± 0.477
0.945HisHis: 0.945 ± 0.368
0.81HisIle: 0.81 ± 0.362
1.214HisLys: 1.214 ± 0.386
3.238HisLeu: 3.238 ± 0.7
0.27HisMet: 0.27 ± 0.167
1.079HisAsn: 1.079 ± 0.5
2.294HisPro: 2.294 ± 0.68
0.81HisGln: 0.81 ± 0.31
2.159HisArg: 2.159 ± 0.598
1.754HisSer: 1.754 ± 0.509
0.81HisThr: 0.81 ± 0.295
1.619HisVal: 1.619 ± 0.456
0.405HisTrp: 0.405 ± 0.221
0.945HisTyr: 0.945 ± 0.332
0.0HisXaa: 0.0 ± 0.0
Ile
2.834IleAla: 2.834 ± 0.898
0.81IleCys: 0.81 ± 0.396
1.619IleAsp: 1.619 ± 0.369
1.754IleGlu: 1.754 ± 0.429
1.484IlePhe: 1.484 ± 0.518
1.889IleGly: 1.889 ± 0.376
0.81IleHis: 0.81 ± 0.31
1.754IleIle: 1.754 ± 0.556
2.024IleLys: 2.024 ± 0.515
5.128IleLeu: 5.128 ± 1.011
1.079IleMet: 1.079 ± 0.265
2.024IleAsn: 2.024 ± 0.574
2.429IlePro: 2.429 ± 0.646
1.214IleGln: 1.214 ± 0.329
2.834IleArg: 2.834 ± 0.818
2.699IleSer: 2.699 ± 0.555
1.754IleThr: 1.754 ± 0.615
2.834IleVal: 2.834 ± 0.726
0.27IleTrp: 0.27 ± 0.166
0.675IleTyr: 0.675 ± 0.352
0.0IleXaa: 0.0 ± 0.0
Lys
2.159LysAla: 2.159 ± 0.536
0.675LysCys: 0.675 ± 0.257
1.484LysAsp: 1.484 ± 0.432
1.754LysGlu: 1.754 ± 0.439
0.945LysPhe: 0.945 ± 0.456
1.214LysGly: 1.214 ± 0.4
0.81LysHis: 0.81 ± 0.427
2.294LysIle: 2.294 ± 0.499
2.834LysLys: 2.834 ± 0.95
2.564LysLeu: 2.564 ± 0.55
1.214LysMet: 1.214 ± 0.523
1.484LysAsn: 1.484 ± 0.423
1.889LysPro: 1.889 ± 0.513
1.619LysGln: 1.619 ± 0.492
3.913LysArg: 3.913 ± 1.054
2.294LysSer: 2.294 ± 0.559
1.754LysThr: 1.754 ± 0.34
1.484LysVal: 1.484 ± 0.496
0.405LysTrp: 0.405 ± 0.318
1.079LysTyr: 1.079 ± 0.341
0.0LysXaa: 0.0 ± 0.0
Leu
7.286LeuAla: 7.286 ± 0.88
1.619LeuCys: 1.619 ± 0.584
5.128LeuAsp: 5.128 ± 0.758
5.667LeuGlu: 5.667 ± 0.994
2.429LeuPhe: 2.429 ± 0.608
5.128LeuGly: 5.128 ± 0.861
3.913LeuHis: 3.913 ± 0.764
4.453LeuIle: 4.453 ± 0.691
5.532LeuLys: 5.532 ± 1.038
9.445LeuLeu: 9.445 ± 1.482
2.564LeuMet: 2.564 ± 0.515
4.588LeuAsn: 4.588 ± 0.883
6.072LeuPro: 6.072 ± 0.943
4.993LeuGln: 4.993 ± 1.048
7.421LeuArg: 7.421 ± 0.774
4.453LeuSer: 4.453 ± 0.822
6.072LeuThr: 6.072 ± 1.231
4.183LeuVal: 4.183 ± 0.614
1.754LeuTrp: 1.754 ± 0.472
1.889LeuTyr: 1.889 ± 0.544
0.0LeuXaa: 0.0 ± 0.0
Met
2.159MetAla: 2.159 ± 0.571
0.27MetCys: 0.27 ± 0.174
0.945MetAsp: 0.945 ± 0.392
1.889MetGlu: 1.889 ± 0.405
1.484MetPhe: 1.484 ± 0.439
0.945MetGly: 0.945 ± 0.301
1.484MetHis: 1.484 ± 0.7
0.945MetIle: 0.945 ± 0.297
0.405MetLys: 0.405 ± 0.218
2.429MetLeu: 2.429 ± 0.632
0.81MetMet: 0.81 ± 0.285
1.079MetAsn: 1.079 ± 0.363
1.079MetPro: 1.079 ± 0.357
1.079MetGln: 1.079 ± 0.281
1.889MetArg: 1.889 ± 0.59
2.024MetSer: 2.024 ± 0.469
2.159MetThr: 2.159 ± 0.597
2.159MetVal: 2.159 ± 0.609
0.27MetTrp: 0.27 ± 0.164
0.405MetTyr: 0.405 ± 0.195
0.0MetXaa: 0.0 ± 0.0
Asn
2.294AsnAla: 2.294 ± 0.618
0.945AsnCys: 0.945 ± 0.57
1.214AsnAsp: 1.214 ± 0.561
2.024AsnGlu: 2.024 ± 0.388
2.429AsnPhe: 2.429 ± 0.597
0.945AsnGly: 0.945 ± 0.317
0.27AsnHis: 0.27 ± 0.183
2.024AsnIle: 2.024 ± 0.713
1.079AsnLys: 1.079 ± 0.376
4.588AsnLeu: 4.588 ± 0.988
1.754AsnMet: 1.754 ± 0.403
1.484AsnAsn: 1.484 ± 0.463
2.969AsnPro: 2.969 ± 0.742
1.214AsnGln: 1.214 ± 0.392
2.834AsnArg: 2.834 ± 0.739
3.913AsnSer: 3.913 ± 0.853
2.024AsnThr: 2.024 ± 0.544
2.294AsnVal: 2.294 ± 0.592
0.405AsnTrp: 0.405 ± 0.286
1.889AsnTyr: 1.889 ± 0.492
0.0AsnXaa: 0.0 ± 0.0
Pro
5.262ProAla: 5.262 ± 0.637
0.405ProCys: 0.405 ± 0.234
3.373ProAsp: 3.373 ± 0.514
6.207ProGlu: 6.207 ± 1.594
2.564ProPhe: 2.564 ± 0.745
5.262ProGly: 5.262 ± 0.754
0.675ProHis: 0.675 ± 0.261
1.619ProIle: 1.619 ± 0.422
2.429ProLys: 2.429 ± 0.541
4.048ProLeu: 4.048 ± 0.809
1.214ProMet: 1.214 ± 0.359
2.564ProAsn: 2.564 ± 0.501
9.445ProPro: 9.445 ± 1.472
3.238ProGln: 3.238 ± 0.95
6.342ProArg: 6.342 ± 1.006
6.612ProSer: 6.612 ± 1.055
4.858ProThr: 4.858 ± 0.852
5.397ProVal: 5.397 ± 1.048
0.675ProTrp: 0.675 ± 0.335
1.484ProTyr: 1.484 ± 0.443
0.0ProXaa: 0.0 ± 0.0
Gln
4.183GlnAla: 4.183 ± 0.742
0.81GlnCys: 0.81 ± 0.295
1.754GlnAsp: 1.754 ± 0.44
4.183GlnGlu: 4.183 ± 0.658
1.079GlnPhe: 1.079 ± 0.425
2.294GlnGly: 2.294 ± 0.615
1.214GlnHis: 1.214 ± 0.421
1.754GlnIle: 1.754 ± 0.403
1.619GlnLys: 1.619 ± 0.458
3.913GlnLeu: 3.913 ± 0.636
0.81GlnMet: 0.81 ± 0.335
1.754GlnAsn: 1.754 ± 0.663
3.643GlnPro: 3.643 ± 0.797
3.508GlnGln: 3.508 ± 0.721
3.778GlnArg: 3.778 ± 0.771
2.834GlnSer: 2.834 ± 0.706
2.159GlnThr: 2.159 ± 0.474
2.429GlnVal: 2.429 ± 0.606
0.27GlnTrp: 0.27 ± 0.201
0.405GlnTyr: 0.405 ± 0.213
0.0GlnXaa: 0.0 ± 0.0
Arg
7.691ArgAla: 7.691 ± 1.161
1.619ArgCys: 1.619 ± 0.624
4.318ArgAsp: 4.318 ± 1.281
4.858ArgGlu: 4.858 ± 1.189
1.889ArgPhe: 1.889 ± 0.379
5.937ArgGly: 5.937 ± 0.987
3.103ArgHis: 3.103 ± 0.464
1.754ArgIle: 1.754 ± 0.42
2.294ArgLys: 2.294 ± 0.567
5.937ArgLeu: 5.937 ± 1.054
1.349ArgMet: 1.349 ± 0.452
3.643ArgAsn: 3.643 ± 0.555
7.017ArgPro: 7.017 ± 1.095
4.723ArgGln: 4.723 ± 0.772
12.684ArgArg: 12.684 ± 3.128
6.072ArgSer: 6.072 ± 1.201
3.238ArgThr: 3.238 ± 0.841
4.588ArgVal: 4.588 ± 1.301
1.349ArgTrp: 1.349 ± 0.387
0.945ArgTyr: 0.945 ± 0.337
0.0ArgXaa: 0.0 ± 0.0
Ser
4.723SerAla: 4.723 ± 1.061
1.349SerCys: 1.349 ± 0.511
2.699SerAsp: 2.699 ± 0.457
4.453SerGlu: 4.453 ± 0.716
2.024SerPhe: 2.024 ± 0.502
6.207SerGly: 6.207 ± 0.941
1.079SerHis: 1.079 ± 0.363
2.294SerIle: 2.294 ± 0.513
2.699SerLys: 2.699 ± 0.568
7.691SerLeu: 7.691 ± 1.16
1.349SerMet: 1.349 ± 0.465
2.834SerAsn: 2.834 ± 0.844
6.072SerPro: 6.072 ± 0.934
2.564SerGln: 2.564 ± 0.654
4.858SerArg: 4.858 ± 0.808
4.723SerSer: 4.723 ± 1.105
4.318SerThr: 4.318 ± 0.77
4.858SerVal: 4.858 ± 0.887
1.079SerTrp: 1.079 ± 0.445
1.484SerTyr: 1.484 ± 0.496
0.0SerXaa: 0.0 ± 0.0
Thr
3.373ThrAla: 3.373 ± 0.812
1.619ThrCys: 1.619 ± 0.459
2.429ThrAsp: 2.429 ± 0.555
3.103ThrGlu: 3.103 ± 0.49
1.889ThrPhe: 1.889 ± 0.52
3.778ThrGly: 3.778 ± 0.699
1.349ThrHis: 1.349 ± 0.351
1.619ThrIle: 1.619 ± 0.583
0.81ThrLys: 0.81 ± 0.265
5.937ThrLeu: 5.937 ± 0.884
1.484ThrMet: 1.484 ± 0.425
1.214ThrAsn: 1.214 ± 0.495
4.588ThrPro: 4.588 ± 0.718
2.159ThrGln: 2.159 ± 0.506
4.858ThrArg: 4.858 ± 0.933
3.643ThrSer: 3.643 ± 0.773
4.453ThrThr: 4.453 ± 0.88
4.588ThrVal: 4.588 ± 0.709
0.27ThrTrp: 0.27 ± 0.147
1.754ThrTyr: 1.754 ± 0.381
0.0ThrXaa: 0.0 ± 0.0
Val
5.532ValAla: 5.532 ± 0.943
1.619ValCys: 1.619 ± 0.418
2.159ValAsp: 2.159 ± 0.51
4.453ValGlu: 4.453 ± 0.791
2.024ValPhe: 2.024 ± 0.723
2.159ValGly: 2.159 ± 0.47
0.81ValHis: 0.81 ± 0.44
2.564ValIle: 2.564 ± 0.53
1.484ValLys: 1.484 ± 0.339
5.937ValLeu: 5.937 ± 0.744
2.294ValMet: 2.294 ± 0.56
1.889ValAsn: 1.889 ± 0.473
4.993ValPro: 4.993 ± 0.819
3.103ValGln: 3.103 ± 0.889
5.667ValArg: 5.667 ± 1.01
5.667ValSer: 5.667 ± 0.829
3.913ValThr: 3.913 ± 0.591
4.993ValVal: 4.993 ± 1.13
0.405ValTrp: 0.405 ± 0.2
2.969ValTyr: 2.969 ± 0.664
0.0ValXaa: 0.0 ± 0.0
Trp
0.405TrpAla: 0.405 ± 0.252
0.135TrpCys: 0.135 ± 0.146
1.349TrpAsp: 1.349 ± 0.608
0.81TrpGlu: 0.81 ± 0.394
0.27TrpPhe: 0.27 ± 0.198
1.214TrpGly: 1.214 ± 0.398
0.0TrpHis: 0.0 ± 0.0
0.27TrpIle: 0.27 ± 0.199
0.54TrpLys: 0.54 ± 0.296
0.81TrpLeu: 0.81 ± 0.304
0.27TrpMet: 0.27 ± 0.244
0.54TrpAsn: 0.54 ± 0.305
0.54TrpPro: 0.54 ± 0.32
0.54TrpGln: 0.54 ± 0.345
0.675TrpArg: 0.675 ± 0.377
0.945TrpSer: 0.945 ± 0.344
0.675TrpThr: 0.675 ± 0.269
0.405TrpVal: 0.405 ± 0.21
0.0TrpTrp: 0.0 ± 0.0
0.405TrpTyr: 0.405 ± 0.275
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.214TyrAla: 1.214 ± 0.423
0.54TyrCys: 0.54 ± 0.247
1.889TyrAsp: 1.889 ± 0.478
1.754TyrGlu: 1.754 ± 0.66
1.079TyrPhe: 1.079 ± 0.413
1.484TyrGly: 1.484 ± 0.634
1.349TyrHis: 1.349 ± 0.351
0.405TyrIle: 0.405 ± 0.253
0.945TyrLys: 0.945 ± 0.32
3.643TyrLeu: 3.643 ± 0.802
0.675TyrMet: 0.675 ± 0.398
1.079TyrAsn: 1.079 ± 0.351
0.54TyrPro: 0.54 ± 0.247
1.349TyrGln: 1.349 ± 0.348
2.024TyrArg: 2.024 ± 0.476
2.024TyrSer: 2.024 ± 0.728
1.349TyrThr: 1.349 ± 0.397
1.619TyrVal: 1.619 ± 0.397
0.675TyrTrp: 0.675 ± 0.28
0.27TyrTyr: 0.27 ± 0.277
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 27 proteins (7412 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski