Amino acid dipepetide frequency for Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton mentagrophytes)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.831AlaAla: 8.831 ± 0.079	0.966AlaCys: 0.966 ± 0.015	4.056AlaAsp: 4.056 ± 0.035	5.118AlaGlu: 5.118 ± 0.047	2.844AlaPhe: 2.844 ± 0.026	5.657AlaGly: 5.657 ± 0.05	1.651AlaHis: 1.651 ± 0.023	4.219AlaIle: 4.219 ± 0.038	4.082AlaLys: 4.082 ± 0.043	7.146AlaLeu: 7.146 ± 0.048	1.827AlaMet: 1.827 ± 0.025	2.917AlaAsn: 2.917 ± 0.03	4.437AlaPro: 4.437 ± 0.044	3.163AlaGln: 3.163 ± 0.038	4.651AlaArg: 4.651 ± 0.041	7.312AlaSer: 7.312 ± 0.051	4.891AlaThr: 4.891 ± 0.039	5.017AlaVal: 5.017 ± 0.042	0.982AlaTrp: 0.982 ± 0.018	1.96AlaTyr: 1.96 ± 0.02	0.0AlaXaa: 0.0 ± 0.0
Cys	0.81CysAla: 0.81 ± 0.015	0.259CysCys: 0.259 ± 0.009	0.587CysAsp: 0.587 ± 0.011	0.595CysGlu: 0.595 ± 0.013	0.567CysPhe: 0.567 ± 0.012	0.866CysGly: 0.866 ± 0.019	0.314CysHis: 0.314 ± 0.01	0.718CysIle: 0.718 ± 0.015	0.508CysLys: 0.508 ± 0.012	1.317CysLeu: 1.317 ± 0.023	0.28CysMet: 0.28 ± 0.009	0.402CysAsn: 0.402 ± 0.011	0.675CysPro: 0.675 ± 0.013	0.432CysGln: 0.432 ± 0.011	0.726CysArg: 0.726 ± 0.015	0.961CysSer: 0.961 ± 0.019	0.631CysThr: 0.631 ± 0.014	0.732CysVal: 0.732 ± 0.017	0.187CysTrp: 0.187 ± 0.007	0.36CysTyr: 0.36 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	4.315AspAla: 4.315 ± 0.033	0.599AspCys: 0.599 ± 0.012	4.272AspAsp: 4.272 ± 0.053	4.633AspGlu: 4.633 ± 0.041	2.051AspPhe: 2.051 ± 0.02	4.002AspGly: 4.002 ± 0.037	1.168AspHis: 1.168 ± 0.017	3.455AspIle: 3.455 ± 0.03	2.601AspLys: 2.601 ± 0.032	4.763AspLeu: 4.763 ± 0.042	1.263AspMet: 1.263 ± 0.019	2.019AspAsn: 2.019 ± 0.025	3.156AspPro: 3.156 ± 0.034	1.827AspGln: 1.827 ± 0.027	2.994AspArg: 2.994 ± 0.032	4.334AspSer: 4.334 ± 0.039	3.105AspThr: 3.105 ± 0.028	3.37AspVal: 3.37 ± 0.031	0.763AspTrp: 0.763 ± 0.014	1.497AspTyr: 1.497 ± 0.02	0.0AspXaa: 0.0 ± 0.0
Glu	5.29GluAla: 5.29 ± 0.044	0.607GluCys: 0.607 ± 0.013	4.375GluAsp: 4.375 ± 0.037	6.266GluGlu: 6.266 ± 0.085	1.952GluPhe: 1.952 ± 0.024	3.706GluGly: 3.706 ± 0.034	1.342GluHis: 1.342 ± 0.018	3.26GluIle: 3.26 ± 0.038	4.284GluLys: 4.284 ± 0.048	5.269GluLeu: 5.269 ± 0.044	1.446GluMet: 1.446 ± 0.019	2.513GluAsn: 2.513 ± 0.028	2.936GluPro: 2.936 ± 0.036	2.574GluGln: 2.574 ± 0.03	4.036GluArg: 4.036 ± 0.042	4.525GluSer: 4.525 ± 0.043	3.516GluThr: 3.516 ± 0.038	3.487GluVal: 3.487 ± 0.034	0.802GluTrp: 0.802 ± 0.014	1.76GluTyr: 1.76 ± 0.026	0.0GluXaa: 0.0 ± 0.0
Phe	2.797PheAla: 2.797 ± 0.032	0.571PheCys: 0.571 ± 0.013	2.225PheAsp: 2.225 ± 0.024	2.041PheGlu: 2.041 ± 0.022	1.916PhePhe: 1.916 ± 0.036	2.59PheGly: 2.59 ± 0.035	0.9PheHis: 0.9 ± 0.014	1.919PheIle: 1.919 ± 0.027	1.572PheLys: 1.572 ± 0.024	3.507PheLeu: 3.507 ± 0.036	0.729PheMet: 0.729 ± 0.014	1.481PheAsn: 1.481 ± 0.018	1.995PhePro: 1.995 ± 0.019	1.323PheGln: 1.323 ± 0.015	1.881PheArg: 1.881 ± 0.024	3.339PheSer: 3.339 ± 0.037	2.114PheThr: 2.114 ± 0.023	2.203PheVal: 2.203 ± 0.028	0.556PheTrp: 0.556 ± 0.012	1.095PheTyr: 1.095 ± 0.018	0.0PheXaa: 0.0 ± 0.0
Gly	4.753GlyAla: 4.753 ± 0.045	0.845GlyCys: 0.845 ± 0.017	3.541GlyAsp: 3.541 ± 0.033	3.779GlyGlu: 3.779 ± 0.037	2.528GlyPhe: 2.528 ± 0.026	5.483GlyGly: 5.483 ± 0.064	1.594GlyHis: 1.594 ± 0.023	3.521GlyIle: 3.521 ± 0.034	3.66GlyLys: 3.66 ± 0.034	5.59GlyLeu: 5.59 ± 0.045	1.552GlyMet: 1.552 ± 0.023	2.528GlyAsn: 2.528 ± 0.027	3.202GlyPro: 3.202 ± 0.034	2.524GlyGln: 2.524 ± 0.027	4.055GlyArg: 4.055 ± 0.037	5.744GlySer: 5.744 ± 0.048	3.764GlyThr: 3.764 ± 0.043	4.052GlyVal: 4.052 ± 0.037	1.032GlyTrp: 1.032 ± 0.017	2.011GlyTyr: 2.011 ± 0.026	0.0GlyXaa: 0.0 ± 0.0
His	1.696HisAla: 1.696 ± 0.021	0.303HisCys: 0.303 ± 0.009	1.275HisAsp: 1.275 ± 0.02	1.278HisGlu: 1.278 ± 0.017	0.891HisPhe: 0.891 ± 0.017	1.695HisGly: 1.695 ± 0.023	0.983HisHis: 0.983 ± 0.028	1.324HisIle: 1.324 ± 0.019	0.907HisLys: 0.907 ± 0.015	2.223HisLeu: 2.223 ± 0.024	0.467HisMet: 0.467 ± 0.01	0.874HisAsn: 0.874 ± 0.016	1.738HisPro: 1.738 ± 0.023	1.141HisGln: 1.141 ± 0.024	1.523HisArg: 1.523 ± 0.022	2.031HisSer: 2.031 ± 0.027	1.299HisThr: 1.299 ± 0.018	1.292HisVal: 1.292 ± 0.019	0.29HisTrp: 0.29 ± 0.009	0.65HisTyr: 0.65 ± 0.014	0.0HisXaa: 0.0 ± 0.0
Ile	3.937IleAla: 3.937 ± 0.035	0.78IleCys: 0.78 ± 0.017	3.034IleAsp: 3.034 ± 0.03	3.041IleGlu: 3.041 ± 0.033	2.113IlePhe: 2.113 ± 0.026	3.058IleGly: 3.058 ± 0.036	1.282IleHis: 1.282 ± 0.019	2.725IleIle: 2.725 ± 0.032	2.44IleLys: 2.44 ± 0.031	4.767IleLeu: 4.767 ± 0.046	1.03IleMet: 1.03 ± 0.017	1.955IleAsn: 1.955 ± 0.026	3.452IlePro: 3.452 ± 0.034	2.028IleGln: 2.028 ± 0.022	2.924IleArg: 2.924 ± 0.03	4.479IleSer: 4.479 ± 0.033	2.895IleThr: 2.895 ± 0.031	3.007IleVal: 3.007 ± 0.033	0.678IleTrp: 0.678 ± 0.014	1.55IleTyr: 1.55 ± 0.025	0.0IleXaa: 0.0 ± 0.0
Lys	4.351LysAla: 4.351 ± 0.044	0.496LysCys: 0.496 ± 0.014	2.966LysAsp: 2.966 ± 0.036	3.921LysGlu: 3.921 ± 0.045	1.554LysPhe: 1.554 ± 0.019	3.173LysGly: 3.173 ± 0.031	1.148LysHis: 1.148 ± 0.019	2.465LysIle: 2.465 ± 0.029	4.239LysLys: 4.239 ± 0.067	4.392LysLeu: 4.392 ± 0.036	1.072LysMet: 1.072 ± 0.018	1.932LysAsn: 1.932 ± 0.021	3.084LysPro: 3.084 ± 0.034	2.141LysGln: 2.141 ± 0.026	3.725LysArg: 3.725 ± 0.041	3.906LysSer: 3.906 ± 0.036	2.891LysThr: 2.891 ± 0.027	2.809LysVal: 2.809 ± 0.032	0.651LysTrp: 0.651 ± 0.015	1.506LysTyr: 1.506 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	7.419LeuAla: 7.419 ± 0.048	1.193LeuCys: 1.193 ± 0.022	5.051LeuAsp: 5.051 ± 0.039	5.498LeuGlu: 5.498 ± 0.048	3.524LeuPhe: 3.524 ± 0.035	5.413LeuGly: 5.413 ± 0.047	2.219LeuHis: 2.219 ± 0.023	4.043LeuIle: 4.043 ± 0.039	4.459LeuLys: 4.459 ± 0.035	8.763LeuLeu: 8.763 ± 0.072	1.658LeuMet: 1.658 ± 0.023	3.23LeuAsn: 3.23 ± 0.032	5.609LeuPro: 5.609 ± 0.042	3.765LeuGln: 3.765 ± 0.039	5.653LeuArg: 5.653 ± 0.043	7.812LeuSer: 7.812 ± 0.054	4.821LeuThr: 4.821 ± 0.037	5.167LeuVal: 5.167 ± 0.043	1.059LeuTrp: 1.059 ± 0.017	2.35LeuTyr: 2.35 ± 0.026	0.0LeuXaa: 0.0 ± 0.0
Met	2.105MetAla: 2.105 ± 0.025	0.218MetCys: 0.218 ± 0.008	1.277MetAsp: 1.277 ± 0.017	1.379MetGlu: 1.379 ± 0.019	0.753MetPhe: 0.753 ± 0.014	1.437MetGly: 1.437 ± 0.021	0.463MetHis: 0.463 ± 0.011	1.025MetIle: 1.025 ± 0.02	1.154MetLys: 1.154 ± 0.017	1.857MetLeu: 1.857 ± 0.023	0.529MetMet: 0.529 ± 0.013	0.832MetAsn: 0.832 ± 0.015	1.153MetPro: 1.153 ± 0.017	0.847MetGln: 0.847 ± 0.015	1.127MetArg: 1.127 ± 0.018	1.711MetSer: 1.711 ± 0.021	1.215MetThr: 1.215 ± 0.018	1.274MetVal: 1.274 ± 0.017	0.211MetTrp: 0.211 ± 0.008	0.496MetTyr: 0.496 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	2.98AsnAla: 2.98 ± 0.028	0.438AsnCys: 0.438 ± 0.011	2.062AsnAsp: 2.062 ± 0.025	2.218AsnGlu: 2.218 ± 0.026	1.363AsnPhe: 1.363 ± 0.019	2.964AsnGly: 2.964 ± 0.034	0.892AsnHis: 0.892 ± 0.015	2.339AsnIle: 2.339 ± 0.029	1.772AsnLys: 1.772 ± 0.023	3.274AsnLeu: 3.274 ± 0.035	0.885AsnMet: 0.885 ± 0.015	1.835AsnAsn: 1.835 ± 0.032	2.548AsnPro: 2.548 ± 0.031	1.398AsnGln: 1.398 ± 0.019	2.021AsnArg: 2.021 ± 0.023	3.063AsnSer: 3.063 ± 0.033	2.366AsnThr: 2.366 ± 0.029	2.213AsnVal: 2.213 ± 0.025	0.5AsnTrp: 0.5 ± 0.013	1.027AsnTyr: 1.027 ± 0.019	0.0AsnXaa: 0.0 ± 0.0
Pro	5.32ProAla: 5.32 ± 0.055	0.569ProCys: 0.569 ± 0.015	3.197ProAsp: 3.197 ± 0.029	3.935ProGlu: 3.935 ± 0.036	2.136ProPhe: 2.136 ± 0.026	3.948ProGly: 3.948 ± 0.046	1.376ProHis: 1.376 ± 0.023	2.657ProIle: 2.657 ± 0.028	2.839ProLys: 2.839 ± 0.03	4.846ProLeu: 4.846 ± 0.044	1.055ProMet: 1.055 ± 0.017	2.254ProAsn: 2.254 ± 0.029	5.578ProPro: 5.578 ± 0.091	2.616ProGln: 2.616 ± 0.034	3.35ProArg: 3.35 ± 0.037	6.495ProSer: 6.495 ± 0.068	4.087ProThr: 4.087 ± 0.059	3.588ProVal: 3.588 ± 0.035	0.653ProTrp: 0.653 ± 0.013	1.482ProTyr: 1.482 ± 0.023	0.0ProXaa: 0.0 ± 0.0
Gln	3.366GlnAla: 3.366 ± 0.034	0.415GlnCys: 0.415 ± 0.012	1.976GlnAsp: 1.976 ± 0.024	2.462GlnGlu: 2.462 ± 0.031	1.281GlnPhe: 1.281 ± 0.018	2.356GlnGly: 2.356 ± 0.028	1.215GlnHis: 1.215 ± 0.023	1.874GlnIle: 1.874 ± 0.025	2.212GlnLys: 2.212 ± 0.028	3.548GlnLeu: 3.548 ± 0.036	0.836GlnMet: 0.836 ± 0.015	1.608GlnAsn: 1.608 ± 0.021	2.877GlnPro: 2.877 ± 0.039	3.28GlnGln: 3.28 ± 0.086	2.755GlnArg: 2.755 ± 0.032	3.231GlnSer: 3.231 ± 0.035	2.268GlnThr: 2.268 ± 0.027	2.066GlnVal: 2.066 ± 0.024	0.495GlnTrp: 0.495 ± 0.011	1.13GlnTyr: 1.13 ± 0.018	0.0GlnXaa: 0.0 ± 0.0
Arg	4.511ArgAla: 4.511 ± 0.042	0.703ArgCys: 0.703 ± 0.016	3.385ArgAsp: 3.385 ± 0.032	4.127ArgGlu: 4.127 ± 0.044	2.033ArgPhe: 2.033 ± 0.025	3.59ArgGly: 3.59 ± 0.039	1.555ArgHis: 1.555 ± 0.021	2.926ArgIle: 2.926 ± 0.03	3.677ArgLys: 3.677 ± 0.039	5.423ArgLeu: 5.423 ± 0.043	1.25ArgMet: 1.25 ± 0.017	2.294ArgAsn: 2.294 ± 0.023	3.524ArgPro: 3.524 ± 0.038	2.691ArgGln: 2.691 ± 0.028	5.299ArgArg: 5.299 ± 0.05	4.946ArgSer: 4.946 ± 0.041	3.119ArgThr: 3.119 ± 0.028	3.226ArgVal: 3.226 ± 0.028	0.843ArgTrp: 0.843 ± 0.015	1.658ArgTyr: 1.658 ± 0.02	0.0ArgXaa: 0.0 ± 0.0
Ser	6.602SerAla: 6.602 ± 0.045	0.922SerCys: 0.922 ± 0.015	4.137SerAsp: 4.137 ± 0.042	4.346SerGlu: 4.346 ± 0.043	3.182SerPhe: 3.182 ± 0.034	5.59SerGly: 5.59 ± 0.047	2.145SerHis: 2.145 ± 0.026	4.378SerIle: 4.378 ± 0.039	4.338SerLys: 4.338 ± 0.036	7.792SerLeu: 7.792 ± 0.052	1.849SerMet: 1.849 ± 0.023	3.44SerAsn: 3.44 ± 0.037	5.994SerPro: 5.994 ± 0.065	3.588SerGln: 3.588 ± 0.038	5.428SerArg: 5.428 ± 0.041	10.381SerSer: 10.381 ± 0.088	6.032SerThr: 6.032 ± 0.05	4.524SerVal: 4.524 ± 0.035	1.036SerTrp: 1.036 ± 0.017	2.103SerTyr: 2.103 ± 0.028	0.0SerXaa: 0.0 ± 0.0
Thr	5.132ThrAla: 5.132 ± 0.037	0.677ThrCys: 0.677 ± 0.016	2.846ThrAsp: 2.846 ± 0.029	3.213ThrGlu: 3.213 ± 0.036	2.079ThrPhe: 2.079 ± 0.024	4.04ThrGly: 4.04 ± 0.047	1.263ThrHis: 1.263 ± 0.018	3.109ThrIle: 3.109 ± 0.035	2.738ThrLys: 2.738 ± 0.027	5.084ThrLeu: 5.084 ± 0.042	1.175ThrMet: 1.175 ± 0.017	2.221ThrAsn: 2.221 ± 0.026	4.501ThrPro: 4.501 ± 0.048	2.092ThrGln: 2.092 ± 0.027	3.028ThrArg: 3.028 ± 0.027	5.708ThrSer: 5.708 ± 0.05	4.281ThrThr: 4.281 ± 0.05	3.502ThrVal: 3.502 ± 0.037	0.711ThrTrp: 0.711 ± 0.013	1.515ThrTyr: 1.515 ± 0.018	0.0ThrXaa: 0.0 ± 0.0
Val	4.661ValAla: 4.661 ± 0.037	0.815ValCys: 0.815 ± 0.016	3.573ValAsp: 3.573 ± 0.032	3.818ValGlu: 3.818 ± 0.039	2.319ValPhe: 2.319 ± 0.029	3.576ValGly: 3.576 ± 0.039	1.294ValHis: 1.294 ± 0.016	2.956ValIle: 2.956 ± 0.033	2.991ValLys: 2.991 ± 0.031	5.217ValLeu: 5.217 ± 0.046	1.232ValMet: 1.232 ± 0.018	2.157ValAsn: 2.157 ± 0.023	3.395ValPro: 3.395 ± 0.037	2.189ValGln: 2.189 ± 0.026	3.191ValArg: 3.191 ± 0.03	4.735ValSer: 4.735 ± 0.035	3.269ValThr: 3.269 ± 0.033	3.941ValVal: 3.941 ± 0.043	0.734ValTrp: 0.734 ± 0.016	1.653ValTyr: 1.653 ± 0.021	0.0ValXaa: 0.0 ± 0.0
Trp	0.954TrpAla: 0.954 ± 0.018	0.163TrpCys: 0.163 ± 0.007	0.792TrpAsp: 0.792 ± 0.014	0.79TrpGlu: 0.79 ± 0.014	0.464TrpPhe: 0.464 ± 0.013	0.755TrpGly: 0.755 ± 0.014	0.306TrpHis: 0.306 ± 0.009	0.69TrpIle: 0.69 ± 0.013	0.812TrpLys: 0.812 ± 0.016	1.223TrpLeu: 1.223 ± 0.02	0.333TrpMet: 0.333 ± 0.009	0.58TrpAsn: 0.58 ± 0.014	0.54TrpPro: 0.54 ± 0.01	0.49TrpGln: 0.49 ± 0.011	0.837TrpArg: 0.837 ± 0.016	0.954TrpSer: 0.954 ± 0.018	0.768TrpThr: 0.768 ± 0.016	0.749TrpVal: 0.749 ± 0.014	0.238TrpTrp: 0.238 ± 0.008	0.357TrpTyr: 0.357 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.898TyrAla: 1.898 ± 0.02	0.385TyrCys: 0.385 ± 0.011	1.563TyrAsp: 1.563 ± 0.019	1.488TyrGlu: 1.488 ± 0.019	1.205TyrPhe: 1.205 ± 0.02	1.858TyrGly: 1.858 ± 0.024	0.767TyrHis: 0.767 ± 0.015	1.571TyrIle: 1.571 ± 0.023	1.139TyrLys: 1.139 ± 0.018	2.706TyrLeu: 2.706 ± 0.025	0.599TyrMet: 0.599 ± 0.011	1.087TyrAsn: 1.087 ± 0.018	1.586TyrPro: 1.586 ± 0.024	1.141TyrGln: 1.141 ± 0.019	1.575TyrArg: 1.575 ± 0.019	2.139TyrSer: 2.139 ± 0.027	1.583TyrThr: 1.583 ± 0.02	1.495TyrVal: 1.495 ± 0.02	0.373TyrTrp: 0.373 ± 0.01	0.894TyrTyr: 0.894 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 7976 proteins (3936409 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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