Amino acid dipepetide frequency for Fusarium graminearum dsRNA mycovirus-4

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
13.71AlaAla: 13.71 ± 4.144
0.0AlaCys: 0.0 ± 0.0
5.998AlaAsp: 5.998 ± 1.635
5.998AlaGlu: 5.998 ± 2.899
1.714AlaPhe: 1.714 ± 0.664
4.284AlaGly: 4.284 ± 2.17
1.714AlaHis: 1.714 ± 0.664
1.714AlaIle: 1.714 ± 1.853
5.998AlaLys: 5.998 ± 1.935
6.855AlaLeu: 6.855 ± 1.715
2.571AlaMet: 2.571 ± 1.903
1.714AlaAsn: 1.714 ± 1.015
5.998AlaPro: 5.998 ± 1.935
4.284AlaGln: 4.284 ± 3.785
6.855AlaArg: 6.855 ± 0.563
5.141AlaSer: 5.141 ± 3.044
9.426AlaThr: 9.426 ± 2.688
5.998AlaVal: 5.998 ± 1.635
0.857AlaTrp: 0.857 ± 0.927
4.284AlaTyr: 4.284 ± 1.508
0.0AlaXaa: 0.0 ± 0.0
Cys
0.857CysAla: 0.857 ± 0.507
0.0CysCys: 0.0 ± 0.0
1.714CysAsp: 1.714 ± 1.015
0.857CysGlu: 0.857 ± 0.507
1.714CysPhe: 1.714 ± 1.015
0.857CysGly: 0.857 ± 0.507
0.857CysHis: 0.857 ± 0.927
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
1.714CysLeu: 1.714 ± 1.962
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.857CysPro: 0.857 ± 0.927
0.0CysGln: 0.0 ± 0.0
0.857CysArg: 0.857 ± 0.927
0.857CysSer: 0.857 ± 0.507
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.998AspAla: 5.998 ± 1.401
0.857AspCys: 0.857 ± 0.927
8.569AspAsp: 8.569 ± 5.073
2.571AspGlu: 2.571 ± 1.785
1.714AspPhe: 1.714 ± 0.664
3.428AspGly: 3.428 ± 1.886
1.714AspHis: 1.714 ± 0.664
0.857AspIle: 0.857 ± 0.507
4.284AspLys: 4.284 ± 1.508
6.855AspLeu: 6.855 ± 2.008
2.571AspMet: 2.571 ± 1.785
2.571AspAsn: 2.571 ± 1.856
4.284AspPro: 4.284 ± 1.243
3.428AspGln: 3.428 ± 3.933
3.428AspArg: 3.428 ± 1.886
2.571AspSer: 2.571 ± 0.733
4.284AspThr: 4.284 ± 1.508
5.998AspVal: 5.998 ± 0.725
2.571AspTrp: 2.571 ± 1.522
4.284AspTyr: 4.284 ± 2.045
0.0AspXaa: 0.0 ± 0.0
Glu
4.284GluAla: 4.284 ± 1.578
0.857GluCys: 0.857 ± 2.183
4.284GluAsp: 4.284 ± 1.508
7.712GluGlu: 7.712 ± 0.789
2.571GluPhe: 2.571 ± 1.522
4.284GluGly: 4.284 ± 2.045
1.714GluHis: 1.714 ± 1.853
3.428GluIle: 3.428 ± 2.06
2.571GluLys: 2.571 ± 1.53
3.428GluLeu: 3.428 ± 2.06
0.857GluMet: 0.857 ± 0.927
2.571GluAsn: 2.571 ± 1.53
4.284GluPro: 4.284 ± 1.508
5.141GluGln: 5.141 ± 3.387
4.284GluArg: 4.284 ± 1.508
2.571GluSer: 2.571 ± 4.27
2.571GluThr: 2.571 ± 1.522
0.857GluVal: 0.857 ± 2.183
1.714GluTrp: 1.714 ± 1.015
0.857GluTyr: 0.857 ± 0.927
0.0GluXaa: 0.0 ± 0.0
Phe
4.284PheAla: 4.284 ± 1.304
0.857PheCys: 0.857 ± 0.507
5.141PheAsp: 5.141 ± 1.467
2.571PheGlu: 2.571 ± 1.522
0.857PhePhe: 0.857 ± 0.507
1.714PheGly: 1.714 ± 1.015
0.857PheHis: 0.857 ± 0.507
0.857PheIle: 0.857 ± 0.507
3.428PheLys: 3.428 ± 2.029
2.571PheLeu: 2.571 ± 4.12
1.714PheMet: 1.714 ± 0.664
2.571PheAsn: 2.571 ± 0.733
1.714PhePro: 1.714 ± 1.015
0.857PheGln: 0.857 ± 0.507
0.857PheArg: 0.857 ± 2.183
1.714PheSer: 1.714 ± 1.015
0.857PheThr: 0.857 ± 0.507
2.571PheVal: 2.571 ± 1.522
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
5.998GlyAla: 5.998 ± 2.82
0.0GlyCys: 0.0 ± 0.0
5.998GlyAsp: 5.998 ± 5.562
1.714GlyGlu: 1.714 ± 1.015
1.714GlyPhe: 1.714 ± 1.015
4.284GlyGly: 4.284 ± 2.17
2.571GlyHis: 2.571 ± 0.733
1.714GlyIle: 1.714 ± 1.015
3.428GlyLys: 3.428 ± 1.072
5.141GlyLeu: 5.141 ± 1.118
4.284GlyMet: 4.284 ± 2.17
2.571GlyAsn: 2.571 ± 1.522
1.714GlyPro: 1.714 ± 0.664
0.857GlyGln: 0.857 ± 0.507
6.855GlyArg: 6.855 ± 2.904
4.284GlySer: 4.284 ± 2.649
4.284GlyThr: 4.284 ± 2.17
3.428GlyVal: 3.428 ± 1.072
1.714GlyTrp: 1.714 ± 1.015
2.571GlyTyr: 2.571 ± 4.12
0.0GlyXaa: 0.0 ± 0.0
His
3.428HisAla: 3.428 ± 1.328
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.714HisGlu: 1.714 ± 0.664
1.714HisPhe: 1.714 ± 1.015
2.571HisGly: 2.571 ± 1.856
0.0HisHis: 0.0 ± 0.0
0.857HisIle: 0.857 ± 0.507
3.428HisLys: 3.428 ± 1.072
1.714HisLeu: 1.714 ± 0.664
2.571HisMet: 2.571 ± 1.856
1.714HisAsn: 1.714 ± 1.015
1.714HisPro: 1.714 ± 0.664
0.857HisGln: 0.857 ± 0.507
1.714HisArg: 1.714 ± 1.015
0.857HisSer: 0.857 ± 0.927
0.857HisThr: 0.857 ± 0.507
0.857HisVal: 0.857 ± 0.927
0.857HisTrp: 0.857 ± 0.927
1.714HisTyr: 1.714 ± 0.664
0.0HisXaa: 0.0 ± 0.0
Ile
3.428IleAla: 3.428 ± 1.328
0.857IleCys: 0.857 ± 0.507
0.857IleAsp: 0.857 ± 0.927
0.0IleGlu: 0.0 ± 0.0
2.571IlePhe: 2.571 ± 1.522
2.571IleGly: 2.571 ± 1.785
0.857IleHis: 0.857 ± 0.507
0.0IleIle: 0.0 ± 0.0
0.857IleLys: 0.857 ± 0.927
2.571IleLeu: 2.571 ± 1.785
0.857IleMet: 0.857 ± 0.507
0.857IleAsn: 0.857 ± 0.927
2.571IlePro: 2.571 ± 1.53
3.428IleGln: 3.428 ± 2.029
3.428IleArg: 3.428 ± 2.029
3.428IleSer: 3.428 ± 1.072
1.714IleThr: 1.714 ± 0.664
0.857IleVal: 0.857 ± 2.183
0.857IleTrp: 0.857 ± 0.927
0.857IleTyr: 0.857 ± 0.507
0.0IleXaa: 0.0 ± 0.0
Lys
4.284LysAla: 4.284 ± 1.508
0.0LysCys: 0.0 ± 0.0
0.0LysAsp: 0.0 ± 0.0
2.571LysGlu: 2.571 ± 2.78
5.141LysPhe: 5.141 ± 3.044
3.428LysGly: 3.428 ± 1.072
0.857LysHis: 0.857 ± 0.507
0.857LysIle: 0.857 ± 0.507
2.571LysLys: 2.571 ± 0.733
5.998LysLeu: 5.998 ± 1.765
0.857LysMet: 0.857 ± 0.927
0.0LysAsn: 0.0 ± 0.0
0.857LysPro: 0.857 ± 0.507
0.857LysGln: 0.857 ± 0.507
3.428LysArg: 3.428 ± 2.441
3.428LysSer: 3.428 ± 1.072
0.857LysThr: 0.857 ± 0.927
2.571LysVal: 2.571 ± 2.78
1.714LysTrp: 1.714 ± 1.853
0.857LysTyr: 0.857 ± 0.507
0.0LysXaa: 0.0 ± 0.0
Leu
5.998LeuAla: 5.998 ± 1.935
2.571LeuCys: 2.571 ± 1.522
8.569LeuAsp: 8.569 ± 2.539
6.855LeuGlu: 6.855 ± 5.342
1.714LeuPhe: 1.714 ± 1.015
9.426LeuGly: 9.426 ± 3.237
0.0LeuHis: 0.0 ± 0.0
3.428LeuIle: 3.428 ± 2.029
0.0LeuLys: 0.0 ± 0.0
9.426LeuLeu: 9.426 ± 4.33
1.714LeuMet: 1.714 ± 1.128
1.714LeuAsn: 1.714 ± 1.015
5.141LeuPro: 5.141 ± 1.223
2.571LeuGln: 2.571 ± 0.733
11.14LeuArg: 11.14 ± 2.644
4.284LeuSer: 4.284 ± 2.17
8.569LeuThr: 8.569 ± 2.607
5.141LeuVal: 5.141 ± 1.223
0.0LeuTrp: 0.0 ± 0.0
1.714LeuTyr: 1.714 ± 1.962
0.0LeuXaa: 0.0 ± 0.0
Met
2.571MetAla: 2.571 ± 1.53
0.0MetCys: 0.0 ± 0.0
0.857MetAsp: 0.857 ± 0.507
0.857MetGlu: 0.857 ± 0.507
1.714MetPhe: 1.714 ± 0.664
2.571MetGly: 2.571 ± 1.53
0.857MetHis: 0.857 ± 2.183
1.714MetIle: 1.714 ± 1.015
0.857MetLys: 0.857 ± 0.507
0.857MetLeu: 0.857 ± 0.507
0.857MetMet: 0.857 ± 0.507
0.857MetAsn: 0.857 ± 0.507
0.857MetPro: 0.857 ± 0.927
0.0MetGln: 0.0 ± 0.0
3.428MetArg: 3.428 ± 3.156
0.857MetSer: 0.857 ± 0.507
1.714MetThr: 1.714 ± 0.664
3.428MetVal: 3.428 ± 4.373
1.714MetTrp: 1.714 ± 1.962
2.571MetTyr: 2.571 ± 0.733
0.0MetXaa: 0.0 ± 0.0
Asn
0.857AsnAla: 0.857 ± 2.183
0.0AsnCys: 0.0 ± 0.0
0.857AsnAsp: 0.857 ± 0.507
0.0AsnGlu: 0.0 ± 0.0
0.0AsnPhe: 0.0 ± 0.0
2.571AsnGly: 2.571 ± 1.785
3.428AsnHis: 3.428 ± 2.029
0.0AsnIle: 0.0 ± 0.0
1.714AsnLys: 1.714 ± 0.664
2.571AsnLeu: 2.571 ± 1.522
0.0AsnMet: 0.0 ± 0.0
0.0AsnAsn: 0.0 ± 0.0
4.284AsnPro: 4.284 ± 1.304
0.0AsnGln: 0.0 ± 0.0
2.571AsnArg: 2.571 ± 1.53
0.857AsnSer: 0.857 ± 0.927
1.714AsnThr: 1.714 ± 1.015
0.857AsnVal: 0.857 ± 0.507
0.0AsnTrp: 0.0 ± 0.0
1.714AsnTyr: 1.714 ± 1.015
0.0AsnXaa: 0.0 ± 0.0
Pro
6.855ProAla: 6.855 ± 4.12
1.714ProCys: 1.714 ± 1.015
4.284ProAsp: 4.284 ± 1.243
5.998ProGlu: 5.998 ± 1.935
1.714ProPhe: 1.714 ± 2.186
3.428ProGly: 3.428 ± 1.452
1.714ProHis: 1.714 ± 1.015
2.571ProIle: 2.571 ± 1.53
0.857ProLys: 0.857 ± 0.507
5.141ProLeu: 5.141 ± 1.979
0.857ProMet: 0.857 ± 0.507
0.857ProAsn: 0.857 ± 0.507
4.284ProPro: 4.284 ± 2.17
4.284ProGln: 4.284 ± 1.304
1.714ProArg: 1.714 ± 1.015
4.284ProSer: 4.284 ± 1.304
4.284ProThr: 4.284 ± 2.17
3.428ProVal: 3.428 ± 2.029
0.857ProTrp: 0.857 ± 0.927
1.714ProTyr: 1.714 ± 0.664
0.0ProXaa: 0.0 ± 0.0
Gln
1.714GlnAla: 1.714 ± 1.015
0.857GlnCys: 0.857 ± 0.927
5.141GlnAsp: 5.141 ± 5.885
1.714GlnGlu: 1.714 ± 0.664
1.714GlnPhe: 1.714 ± 1.015
3.428GlnGly: 3.428 ± 1.886
0.857GlnHis: 0.857 ± 0.927
0.0GlnIle: 0.0 ± 0.0
0.857GlnLys: 0.857 ± 0.927
5.141GlnLeu: 5.141 ± 1.467
3.428GlnMet: 3.428 ± 1.072
0.0GlnAsn: 0.0 ± 0.0
0.0GlnPro: 0.0 ± 0.0
2.571GlnGln: 2.571 ± 0.733
5.141GlnArg: 5.141 ± 1.223
4.284GlnSer: 4.284 ± 1.508
0.857GlnThr: 0.857 ± 0.507
1.714GlnVal: 1.714 ± 0.664
1.714GlnTrp: 1.714 ± 4.366
2.571GlnTyr: 2.571 ± 0.733
0.0GlnXaa: 0.0 ± 0.0
Arg
8.569ArgAla: 8.569 ± 0.139
0.0ArgCys: 0.0 ± 0.0
5.998ArgAsp: 5.998 ± 1.401
4.284ArgGlu: 4.284 ± 4.661
1.714ArgPhe: 1.714 ± 1.962
5.141ArgGly: 5.141 ± 1.992
5.141ArgHis: 5.141 ± 1.467
5.141ArgIle: 5.141 ± 2.142
5.141ArgLys: 5.141 ± 1.467
6.855ArgLeu: 6.855 ± 1.715
0.857ArgMet: 0.857 ± 0.927
0.857ArgAsn: 0.857 ± 0.927
6.855ArgPro: 6.855 ± 1.129
3.428ArgGln: 3.428 ± 1.072
8.569ArgArg: 8.569 ± 2.815
2.571ArgSer: 2.571 ± 0.733
4.284ArgThr: 4.284 ± 1.243
3.428ArgVal: 3.428 ± 1.328
3.428ArgTrp: 3.428 ± 1.886
0.857ArgTyr: 0.857 ± 0.507
0.0ArgXaa: 0.0 ± 0.0
Ser
5.141SerAla: 5.141 ± 1.979
0.857SerCys: 0.857 ± 0.507
5.998SerAsp: 5.998 ± 0.725
3.428SerGlu: 3.428 ± 1.886
2.571SerPhe: 2.571 ± 0.733
1.714SerGly: 1.714 ± 0.664
0.0SerHis: 0.0 ± 0.0
3.428SerIle: 3.428 ± 1.072
1.714SerLys: 1.714 ± 1.853
8.569SerLeu: 8.569 ± 2.482
1.714SerMet: 1.714 ± 1.853
0.0SerAsn: 0.0 ± 0.0
3.428SerPro: 3.428 ± 1.328
2.571SerGln: 2.571 ± 1.522
3.428SerArg: 3.428 ± 2.441
5.998SerSer: 5.998 ± 2.464
1.714SerThr: 1.714 ± 2.186
2.571SerVal: 2.571 ± 1.522
0.857SerTrp: 0.857 ± 0.507
1.714SerTyr: 1.714 ± 0.664
0.0SerXaa: 0.0 ± 0.0
Thr
5.141ThrAla: 5.141 ± 1.118
0.857ThrCys: 0.857 ± 0.927
3.428ThrAsp: 3.428 ± 1.328
2.571ThrGlu: 2.571 ± 1.522
2.571ThrPhe: 2.571 ± 1.522
4.284ThrGly: 4.284 ± 2.649
1.714ThrHis: 1.714 ± 0.664
1.714ThrIle: 1.714 ± 0.664
1.714ThrLys: 1.714 ± 0.664
4.284ThrLeu: 4.284 ± 1.243
0.857ThrMet: 0.857 ± 2.183
1.714ThrAsn: 1.714 ± 1.962
5.141ThrPro: 5.141 ± 1.979
1.714ThrGln: 1.714 ± 1.853
4.284ThrArg: 4.284 ± 1.578
5.141ThrSer: 5.141 ± 1.467
4.284ThrThr: 4.284 ± 1.508
5.998ThrVal: 5.998 ± 2.464
0.0ThrTrp: 0.0 ± 0.0
1.714ThrTyr: 1.714 ± 1.015
0.0ThrXaa: 0.0 ± 0.0
Val
5.141ValAla: 5.141 ± 1.118
0.0ValCys: 0.0 ± 0.0
3.428ValAsp: 3.428 ± 1.072
5.998ValGlu: 5.998 ± 1.401
0.857ValPhe: 0.857 ± 2.183
3.428ValGly: 3.428 ± 1.072
3.428ValHis: 3.428 ± 2.029
2.571ValIle: 2.571 ± 0.733
0.857ValLys: 0.857 ± 0.927
3.428ValLeu: 3.428 ± 2.06
0.0ValMet: 0.0 ± 0.0
1.714ValAsn: 1.714 ± 0.664
3.428ValPro: 3.428 ± 2.06
3.428ValGln: 3.428 ± 1.452
6.855ValArg: 6.855 ± 2.144
2.571ValSer: 2.571 ± 0.733
3.428ValThr: 3.428 ± 3.923
3.428ValVal: 3.428 ± 2.06
0.857ValTrp: 0.857 ± 0.927
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
1.714TrpAla: 1.714 ± 2.186
0.0TrpCys: 0.0 ± 0.0
0.857TrpAsp: 0.857 ± 0.507
3.428TrpGlu: 3.428 ± 1.452
1.714TrpPhe: 1.714 ± 0.664
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.714TrpIle: 1.714 ± 1.962
0.857TrpLys: 0.857 ± 0.927
4.284TrpLeu: 4.284 ± 1.304
0.0TrpMet: 0.0 ± 0.0
0.857TrpAsn: 0.857 ± 0.927
0.857TrpPro: 0.857 ± 0.507
0.0TrpGln: 0.0 ± 0.0
0.857TrpArg: 0.857 ± 0.507
0.0TrpSer: 0.0 ± 0.0
0.857TrpThr: 0.857 ± 0.507
1.714TrpVal: 1.714 ± 1.962
0.0TrpTrp: 0.0 ± 0.0
0.857TrpTyr: 0.857 ± 0.507
0.0TrpXaa: 0.0 ± 0.0
Tyr
5.141TyrAla: 5.141 ± 1.223
0.857TyrCys: 0.857 ± 0.507
0.857TyrAsp: 0.857 ± 0.507
0.0TyrGlu: 0.0 ± 0.0
0.0TyrPhe: 0.0 ± 0.0
1.714TyrGly: 1.714 ± 1.962
0.857TyrHis: 0.857 ± 2.183
0.857TyrIle: 0.857 ± 0.507
0.0TyrLys: 0.0 ± 0.0
3.428TyrLeu: 3.428 ± 1.328
1.714TyrMet: 1.714 ± 1.015
0.857TyrAsn: 0.857 ± 0.507
2.571TyrPro: 2.571 ± 1.856
3.428TyrGln: 3.428 ± 1.328
3.428TyrArg: 3.428 ± 1.072
1.714TyrSer: 1.714 ± 0.664
2.571TyrThr: 2.571 ± 1.522
0.0TyrVal: 0.0 ± 0.0
0.857TyrTrp: 0.857 ± 0.507
1.714TyrTyr: 1.714 ± 1.015
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1168 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski