Amino acid dipepetide frequency for Tortoise microvirus 59

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.962AlaAla: 5.962 ± 1.924
1.084AlaCys: 1.084 ± 0.794
3.794AlaAsp: 3.794 ± 1.677
5.42AlaGlu: 5.42 ± 1.948
2.71AlaPhe: 2.71 ± 1.483
5.962AlaGly: 5.962 ± 3.728
0.542AlaHis: 0.542 ± 0.48
2.71AlaIle: 2.71 ± 1.099
3.252AlaLys: 3.252 ± 1.275
6.504AlaLeu: 6.504 ± 1.513
2.168AlaMet: 2.168 ± 1.14
4.336AlaAsn: 4.336 ± 1.377
4.878AlaPro: 4.878 ± 1.993
5.962AlaGln: 5.962 ± 2.397
2.71AlaArg: 2.71 ± 0.826
7.588AlaSer: 7.588 ± 1.784
5.42AlaThr: 5.42 ± 1.344
5.42AlaVal: 5.42 ± 1.473
0.0AlaTrp: 0.0 ± 0.0
2.71AlaTyr: 2.71 ± 0.745
0.0AlaXaa: 0.0 ± 0.0
Cys
0.542CysAla: 0.542 ± 0.64
0.0CysCys: 0.0 ± 0.0
0.542CysAsp: 0.542 ± 0.39
0.542CysGlu: 0.542 ± 0.864
0.0CysPhe: 0.0 ± 0.0
1.084CysGly: 1.084 ± 0.461
1.084CysHis: 1.084 ± 0.794
0.0CysIle: 0.0 ± 0.0
1.084CysLys: 1.084 ± 0.794
2.168CysLeu: 2.168 ± 1.528
0.0CysMet: 0.0 ± 0.0
1.084CysAsn: 1.084 ± 0.767
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
2.71CysArg: 2.71 ± 1.298
0.542CysSer: 0.542 ± 0.39
1.626CysThr: 1.626 ± 1.233
1.084CysVal: 1.084 ± 1.062
0.0CysTrp: 0.0 ± 0.0
1.084CysTyr: 1.084 ± 1.728
0.0CysXaa: 0.0 ± 0.0
Asp
7.046AspAla: 7.046 ± 3.017
1.084AspCys: 1.084 ± 0.633
4.878AspAsp: 4.878 ± 1.84
0.542AspGlu: 0.542 ± 0.39
7.046AspPhe: 7.046 ± 2.3
2.71AspGly: 2.71 ± 1.206
0.542AspHis: 0.542 ± 0.39
3.794AspIle: 3.794 ± 1.255
3.252AspLys: 3.252 ± 1.114
5.962AspLeu: 5.962 ± 2.066
1.626AspMet: 1.626 ± 0.961
1.084AspAsn: 1.084 ± 0.633
0.542AspPro: 0.542 ± 0.864
1.084AspGln: 1.084 ± 0.96
3.252AspArg: 3.252 ± 1.198
3.794AspSer: 3.794 ± 1.974
3.252AspThr: 3.252 ± 1.288
4.878AspVal: 4.878 ± 1.338
0.542AspTrp: 0.542 ± 0.488
4.878AspTyr: 4.878 ± 1.051
0.0AspXaa: 0.0 ± 0.0
Glu
2.71GluAla: 2.71 ± 1.312
0.0GluCys: 0.0 ± 0.0
0.542GluAsp: 0.542 ± 0.48
1.626GluGlu: 1.626 ± 0.8
1.626GluPhe: 1.626 ± 0.729
1.084GluGly: 1.084 ± 0.975
1.084GluHis: 1.084 ± 0.827
2.168GluIle: 2.168 ± 1.131
3.252GluLys: 3.252 ± 1.11
4.336GluLeu: 4.336 ± 2.22
2.168GluMet: 2.168 ± 0.612
1.626GluAsn: 1.626 ± 0.919
2.168GluPro: 2.168 ± 1.279
3.794GluGln: 3.794 ± 1.671
4.336GluArg: 4.336 ± 1.987
3.794GluSer: 3.794 ± 1.341
1.084GluThr: 1.084 ± 0.726
4.878GluVal: 4.878 ± 2.383
0.542GluTrp: 0.542 ± 0.488
2.71GluTyr: 2.71 ± 1.589
0.0GluXaa: 0.0 ± 0.0
Phe
3.794PheAla: 3.794 ± 1.845
1.084PheCys: 1.084 ± 0.975
3.252PheAsp: 3.252 ± 1.787
3.794PheGlu: 3.794 ± 1.533
2.168PhePhe: 2.168 ± 1.453
3.252PheGly: 3.252 ± 1.282
0.542PheHis: 0.542 ± 0.48
4.336PheIle: 4.336 ± 1.423
2.168PheLys: 2.168 ± 1.642
2.71PheLeu: 2.71 ± 1.798
1.626PheMet: 1.626 ± 0.961
2.71PheAsn: 2.71 ± 1.002
2.168PhePro: 2.168 ± 1.099
2.168PheGln: 2.168 ± 1.396
1.626PheArg: 1.626 ± 1.409
2.71PheSer: 2.71 ± 1.091
3.794PheThr: 3.794 ± 1.464
0.0PheVal: 0.0 ± 0.0
0.542PheTrp: 0.542 ± 0.48
1.084PheTyr: 1.084 ± 0.726
0.0PheXaa: 0.0 ± 0.0
Gly
2.168GlyAla: 2.168 ± 1.115
1.084GlyCys: 1.084 ± 0.633
4.878GlyAsp: 4.878 ± 1.139
2.168GlyGlu: 2.168 ± 0.797
2.71GlyPhe: 2.71 ± 1.405
2.168GlyGly: 2.168 ± 0.797
1.084GlyHis: 1.084 ± 0.539
2.168GlyIle: 2.168 ± 0.617
1.084GlyLys: 1.084 ± 0.827
8.672GlyLeu: 8.672 ± 1.503
1.626GlyMet: 1.626 ± 0.675
3.252GlyAsn: 3.252 ± 1.894
0.0GlyPro: 0.0 ± 0.0
1.084GlyGln: 1.084 ± 0.96
2.71GlyArg: 2.71 ± 0.852
7.588GlySer: 7.588 ± 2.42
2.168GlyThr: 2.168 ± 0.617
6.504GlyVal: 6.504 ± 1.145
0.542GlyTrp: 0.542 ± 0.488
4.336GlyTyr: 4.336 ± 1.229
0.0GlyXaa: 0.0 ± 0.0
His
1.626HisAla: 1.626 ± 0.807
0.0HisCys: 0.0 ± 0.0
0.542HisAsp: 0.542 ± 0.64
0.0HisGlu: 0.0 ± 0.0
0.542HisPhe: 0.542 ± 0.48
2.168HisGly: 2.168 ± 0.761
0.0HisHis: 0.0 ± 0.0
0.542HisIle: 0.542 ± 0.701
0.542HisLys: 0.542 ± 0.488
2.168HisLeu: 2.168 ± 0.827
0.0HisMet: 0.0 ± 0.0
1.626HisAsn: 1.626 ± 0.931
0.542HisPro: 0.542 ± 0.39
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
1.084HisSer: 1.084 ± 0.558
2.71HisThr: 2.71 ± 1.052
1.626HisVal: 1.626 ± 0.942
0.0HisTrp: 0.0 ± 0.0
1.626HisTyr: 1.626 ± 0.44
0.0HisXaa: 0.0 ± 0.0
Ile
5.962IleAla: 5.962 ± 1.391
1.084IleCys: 1.084 ± 1.062
3.794IleAsp: 3.794 ± 2.888
1.626IleGlu: 1.626 ± 1.488
1.084IlePhe: 1.084 ± 1.063
3.252IleGly: 3.252 ± 1.382
0.542IleHis: 0.542 ± 0.488
0.0IleIle: 0.0 ± 0.0
1.084IleLys: 1.084 ± 1.035
3.252IleLeu: 3.252 ± 1.307
0.542IleMet: 0.542 ± 0.39
1.626IleAsn: 1.626 ± 0.809
6.504IlePro: 6.504 ± 1.597
1.626IleGln: 1.626 ± 0.861
2.168IleArg: 2.168 ± 0.834
3.252IleSer: 3.252 ± 1.486
2.168IleThr: 2.168 ± 1.036
1.626IleVal: 1.626 ± 0.44
0.542IleTrp: 0.542 ± 0.39
1.084IleTyr: 1.084 ± 0.709
0.0IleXaa: 0.0 ± 0.0
Lys
2.71LysAla: 2.71 ± 1.598
0.0LysCys: 0.0 ± 0.0
1.084LysAsp: 1.084 ± 1.075
2.71LysGlu: 2.71 ± 0.904
1.084LysPhe: 1.084 ± 0.897
2.168LysGly: 2.168 ± 0.981
0.0LysHis: 0.0 ± 0.0
1.626LysIle: 1.626 ± 0.765
0.542LysLys: 0.542 ± 0.701
4.336LysLeu: 4.336 ± 1.166
2.168LysMet: 2.168 ± 1.028
3.252LysAsn: 3.252 ± 1.09
0.542LysPro: 0.542 ± 0.751
2.168LysGln: 2.168 ± 1.074
1.626LysArg: 1.626 ± 1.219
3.252LysSer: 3.252 ± 1.599
3.794LysThr: 3.794 ± 2.306
1.084LysVal: 1.084 ± 0.558
0.0LysTrp: 0.0 ± 0.0
2.71LysTyr: 2.71 ± 2.438
0.0LysXaa: 0.0 ± 0.0
Leu
7.588LeuAla: 7.588 ± 1.281
2.71LeuCys: 2.71 ± 1.45
5.962LeuAsp: 5.962 ± 2.274
3.794LeuGlu: 3.794 ± 1.71
4.336LeuPhe: 4.336 ± 1.79
11.382LeuGly: 11.382 ± 2.724
1.084LeuHis: 1.084 ± 0.461
1.626LeuIle: 1.626 ± 0.666
2.168LeuLys: 2.168 ± 1.074
7.046LeuLeu: 7.046 ± 3.336
1.084LeuMet: 1.084 ± 1.28
4.878LeuAsn: 4.878 ± 1.439
8.13LeuPro: 8.13 ± 2.429
3.794LeuGln: 3.794 ± 0.961
4.336LeuArg: 4.336 ± 0.897
10.84LeuSer: 10.84 ± 1.291
7.046LeuThr: 7.046 ± 2.847
2.168LeuVal: 2.168 ± 1.544
1.626LeuTrp: 1.626 ± 1.169
3.794LeuTyr: 3.794 ± 1.763
0.0LeuXaa: 0.0 ± 0.0
Met
4.336MetAla: 4.336 ± 1.51
0.0MetCys: 0.0 ± 0.0
1.084MetAsp: 1.084 ± 0.827
0.0MetGlu: 0.0 ± 0.0
0.542MetPhe: 0.542 ± 0.488
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.542MetIle: 0.542 ± 0.39
2.168MetLys: 2.168 ± 1.607
1.626MetLeu: 1.626 ± 0.694
0.542MetMet: 0.542 ± 0.39
0.0MetAsn: 0.0 ± 0.0
1.626MetPro: 1.626 ± 0.804
1.084MetGln: 1.084 ± 0.96
1.084MetArg: 1.084 ± 0.539
4.878MetSer: 4.878 ± 1.477
1.626MetThr: 1.626 ± 0.694
0.542MetVal: 0.542 ± 0.48
0.0MetTrp: 0.0 ± 0.0
3.252MetTyr: 3.252 ± 1.071
0.0MetXaa: 0.0 ± 0.0
Asn
4.336AsnAla: 4.336 ± 1.477
0.0AsnCys: 0.0 ± 0.0
2.168AsnAsp: 2.168 ± 1.15
4.878AsnGlu: 4.878 ± 1.38
3.794AsnPhe: 3.794 ± 1.021
2.71AsnGly: 2.71 ± 1.366
0.542AsnHis: 0.542 ± 0.39
1.084AsnIle: 1.084 ± 0.539
2.71AsnLys: 2.71 ± 1.298
3.252AsnLeu: 3.252 ± 1.126
1.084AsnMet: 1.084 ± 0.558
1.626AsnAsn: 1.626 ± 0.807
3.252AsnPro: 3.252 ± 1.433
1.626AsnGln: 1.626 ± 0.943
3.252AsnArg: 3.252 ± 0.886
1.626AsnSer: 1.626 ± 0.729
3.794AsnThr: 3.794 ± 1.543
3.794AsnVal: 3.794 ± 1.903
1.084AsnTrp: 1.084 ± 0.829
3.252AsnTyr: 3.252 ± 0.781
0.0AsnXaa: 0.0 ± 0.0
Pro
2.71ProAla: 2.71 ± 0.654
1.626ProCys: 1.626 ± 1.874
3.794ProAsp: 3.794 ± 1.038
3.252ProGlu: 3.252 ± 1.855
1.626ProPhe: 1.626 ± 0.865
0.542ProGly: 0.542 ± 0.39
1.626ProHis: 1.626 ± 1.105
4.878ProIle: 4.878 ± 2.047
1.626ProLys: 1.626 ± 1.248
3.252ProLeu: 3.252 ± 0.716
2.168ProMet: 2.168 ± 0.697
2.71ProAsn: 2.71 ± 1.481
1.626ProPro: 1.626 ± 1.09
2.168ProGln: 2.168 ± 1.15
2.71ProArg: 2.71 ± 1.296
10.298ProSer: 10.298 ± 1.757
3.252ProThr: 3.252 ± 1.274
6.504ProVal: 6.504 ± 3.953
0.0ProTrp: 0.0 ± 0.0
2.168ProTyr: 2.168 ± 1.559
0.0ProXaa: 0.0 ± 0.0
Gln
3.794GlnAla: 3.794 ± 1.74
0.542GlnCys: 0.542 ± 0.488
3.794GlnAsp: 3.794 ± 1.255
1.626GlnGlu: 1.626 ± 0.919
2.71GlnPhe: 2.71 ± 1.862
1.626GlnGly: 1.626 ± 0.44
1.626GlnHis: 1.626 ± 1.021
1.084GlnIle: 1.084 ± 0.827
1.084GlnLys: 1.084 ± 0.96
3.252GlnLeu: 3.252 ± 2.307
0.542GlnMet: 0.542 ± 0.488
3.794GlnAsn: 3.794 ± 2.173
0.542GlnPro: 0.542 ± 0.39
5.962GlnGln: 5.962 ± 4.703
3.794GlnArg: 3.794 ± 1.258
3.794GlnSer: 3.794 ± 1.354
2.71GlnThr: 2.71 ± 1.269
2.71GlnVal: 2.71 ± 1.269
0.542GlnTrp: 0.542 ± 0.48
1.084GlnTyr: 1.084 ± 0.758
0.0GlnXaa: 0.0 ± 0.0
Arg
3.794ArgAla: 3.794 ± 1.554
0.542ArgCys: 0.542 ± 0.39
3.252ArgAsp: 3.252 ± 0.909
2.71ArgGlu: 2.71 ± 0.763
0.542ArgPhe: 0.542 ± 0.48
3.794ArgGly: 3.794 ± 0.938
0.542ArgHis: 0.542 ± 0.48
3.252ArgIle: 3.252 ± 1.592
1.626ArgLys: 1.626 ± 1.248
6.504ArgLeu: 6.504 ± 1.338
0.542ArgMet: 0.542 ± 0.48
2.71ArgAsn: 2.71 ± 0.95
4.336ArgPro: 4.336 ± 1.929
3.794ArgGln: 3.794 ± 1.676
3.794ArgArg: 3.794 ± 1.081
3.794ArgSer: 3.794 ± 0.806
2.168ArgThr: 2.168 ± 0.994
3.252ArgVal: 3.252 ± 1.528
0.0ArgTrp: 0.0 ± 0.0
4.336ArgTyr: 4.336 ± 1.423
0.0ArgXaa: 0.0 ± 0.0
Ser
5.42SerAla: 5.42 ± 1.573
1.084SerCys: 1.084 ± 0.975
4.878SerAsp: 4.878 ± 2.048
3.794SerGlu: 3.794 ± 1.18
2.71SerPhe: 2.71 ± 1.205
5.962SerGly: 5.962 ± 1.554
2.168SerHis: 2.168 ± 0.618
3.252SerIle: 3.252 ± 1.37
3.252SerLys: 3.252 ± 1.703
11.382SerLeu: 11.382 ± 2.03
1.084SerMet: 1.084 ± 1.035
2.168SerAsn: 2.168 ± 0.761
8.13SerPro: 8.13 ± 1.216
2.71SerGln: 2.71 ± 1.001
4.336SerArg: 4.336 ± 1.744
8.13SerSer: 8.13 ± 2.735
5.962SerThr: 5.962 ± 1.619
6.504SerVal: 6.504 ± 2.054
0.0SerTrp: 0.0 ± 0.0
3.794SerTyr: 3.794 ± 1.196
0.0SerXaa: 0.0 ± 0.0
Thr
5.962ThrAla: 5.962 ± 1.621
0.0ThrCys: 0.0 ± 0.0
3.794ThrAsp: 3.794 ± 0.815
3.252ThrGlu: 3.252 ± 1.523
5.42ThrPhe: 5.42 ± 1.648
2.71ThrGly: 2.71 ± 1.318
1.084ThrHis: 1.084 ± 0.975
2.168ThrIle: 2.168 ± 0.618
3.252ThrLys: 3.252 ± 1.126
7.046ThrLeu: 7.046 ± 2.993
2.168ThrMet: 2.168 ± 0.827
1.084ThrAsn: 1.084 ± 0.539
4.878ThrPro: 4.878 ± 1.954
2.71ThrGln: 2.71 ± 1.064
2.168ThrArg: 2.168 ± 0.953
2.71ThrSer: 2.71 ± 0.826
3.794ThrThr: 3.794 ± 1.722
4.878ThrVal: 4.878 ± 0.881
0.0ThrTrp: 0.0 ± 0.0
3.252ThrTyr: 3.252 ± 0.947
0.0ThrXaa: 0.0 ± 0.0
Val
4.336ValAla: 4.336 ± 1.287
1.626ValCys: 1.626 ± 1.347
6.504ValAsp: 6.504 ± 1.443
1.626ValGlu: 1.626 ± 1.222
1.626ValPhe: 1.626 ± 1.09
3.252ValGly: 3.252 ± 1.911
1.084ValHis: 1.084 ± 0.633
4.336ValIle: 4.336 ± 1.315
1.626ValLys: 1.626 ± 1.214
7.588ValLeu: 7.588 ± 1.007
1.626ValMet: 1.626 ± 1.445
4.878ValAsn: 4.878 ± 1.194
6.504ValPro: 6.504 ± 2.082
1.084ValGln: 1.084 ± 0.733
4.336ValArg: 4.336 ± 1.962
3.252ValSer: 3.252 ± 1.082
3.252ValThr: 3.252 ± 1.441
2.168ValVal: 2.168 ± 1.212
0.0ValTrp: 0.0 ± 0.0
0.542ValTyr: 0.542 ± 0.751
0.0ValXaa: 0.0 ± 0.0
Trp
0.542TrpAla: 0.542 ± 0.48
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.542TrpLeu: 0.542 ± 0.488
0.0TrpMet: 0.0 ± 0.0
1.626TrpAsn: 1.626 ± 0.809
0.0TrpPro: 0.0 ± 0.0
0.542TrpGln: 0.542 ± 0.48
1.084TrpArg: 1.084 ± 0.827
1.626TrpSer: 1.626 ± 0.865
0.542TrpThr: 0.542 ± 0.488
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.794TyrAla: 3.794 ± 1.436
1.626TyrCys: 1.626 ± 0.701
3.252TyrAsp: 3.252 ± 1.73
2.168TyrGlu: 2.168 ± 0.618
3.252TyrPhe: 3.252 ± 1.178
2.168TyrGly: 2.168 ± 0.952
2.168TyrHis: 2.168 ± 1.748
3.252TyrIle: 3.252 ± 1.41
1.084TyrLys: 1.084 ± 0.558
3.794TyrLeu: 3.794 ± 1.471
1.626TyrMet: 1.626 ± 0.921
3.794TyrAsn: 3.794 ± 0.91
2.168TyrPro: 2.168 ± 1.075
3.252TyrGln: 3.252 ± 0.781
3.252TyrArg: 3.252 ± 1.382
2.168TyrSer: 2.168 ± 1.036
2.168TyrThr: 2.168 ± 1.15
2.168TyrVal: 2.168 ± 1.086
0.542TyrTrp: 0.542 ± 0.488
2.71TyrTyr: 2.71 ± 1.064
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (1846 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski