Amino acid dipepetide frequency for Nocardioides currus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.79AlaAla: 18.79 ± 0.197	0.97AlaCys: 0.97 ± 0.024	8.653AlaAsp: 8.653 ± 0.082	7.501AlaGlu: 7.501 ± 0.088	3.559AlaPhe: 3.559 ± 0.056	12.158AlaGly: 12.158 ± 0.104	2.576AlaHis: 2.576 ± 0.05	4.731AlaIle: 4.731 ± 0.069	2.51AlaLys: 2.51 ± 0.054	13.155AlaLeu: 13.155 ± 0.137	2.849AlaMet: 2.849 ± 0.046	2.123AlaAsn: 2.123 ± 0.047	6.159AlaPro: 6.159 ± 0.093	3.391AlaGln: 3.391 ± 0.056	9.271AlaArg: 9.271 ± 0.089	6.851AlaSer: 6.851 ± 0.078	8.066AlaThr: 8.066 ± 0.107	11.501AlaVal: 11.501 ± 0.114	2.073AlaTrp: 2.073 ± 0.039	2.543AlaTyr: 2.543 ± 0.046	0.0AlaXaa: 0.0 ± 0.0
Cys	0.796CysAla: 0.796 ± 0.026	0.093CysCys: 0.093 ± 0.008	0.494CysAsp: 0.494 ± 0.021	0.358CysGlu: 0.358 ± 0.015	0.223CysPhe: 0.223 ± 0.013	0.838CysGly: 0.838 ± 0.027	0.183CysHis: 0.183 ± 0.012	0.194CysIle: 0.194 ± 0.012	0.106CysLys: 0.106 ± 0.008	0.638CysLeu: 0.638 ± 0.023	0.111CysMet: 0.111 ± 0.009	0.14CysAsn: 0.14 ± 0.011	0.444CysPro: 0.444 ± 0.019	0.16CysGln: 0.16 ± 0.011	0.54CysArg: 0.54 ± 0.022	0.469CysSer: 0.469 ± 0.019	0.466CysThr: 0.466 ± 0.021	0.592CysVal: 0.592 ± 0.024	0.116CysTrp: 0.116 ± 0.011	0.128CysTyr: 0.128 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	8.232AspAla: 8.232 ± 0.085	0.342AspCys: 0.342 ± 0.016	5.068AspAsp: 5.068 ± 0.066	4.801AspGlu: 4.801 ± 0.06	1.817AspPhe: 1.817 ± 0.04	6.652AspGly: 6.652 ± 0.084	1.58AspHis: 1.58 ± 0.037	2.075AspIle: 2.075 ± 0.037	1.163AspLys: 1.163 ± 0.036	7.661AspLeu: 7.661 ± 0.085	0.892AspMet: 0.892 ± 0.026	1.166AspAsn: 1.166 ± 0.032	4.526AspPro: 4.526 ± 0.053	1.938AspGln: 1.938 ± 0.041	5.003AspArg: 5.003 ± 0.07	2.708AspSer: 2.708 ± 0.047	3.215AspThr: 3.215 ± 0.051	6.486AspVal: 6.486 ± 0.082	1.027AspTrp: 1.027 ± 0.032	1.277AspTyr: 1.277 ± 0.03	0.0AspXaa: 0.0 ± 0.0
Glu	6.992GluAla: 6.992 ± 0.09	0.345GluCys: 0.345 ± 0.017	3.205GluAsp: 3.205 ± 0.055	3.136GluGlu: 3.136 ± 0.06	1.464GluPhe: 1.464 ± 0.036	4.182GluGly: 4.182 ± 0.055	1.678GluHis: 1.678 ± 0.038	2.441GluIle: 2.441 ± 0.042	1.344GluLys: 1.344 ± 0.039	6.267GluLeu: 6.267 ± 0.077	1.048GluMet: 1.048 ± 0.029	0.84GluAsn: 0.84 ± 0.025	3.164GluPro: 3.164 ± 0.055	2.285GluGln: 2.285 ± 0.041	4.973GluArg: 4.973 ± 0.067	2.918GluSer: 2.918 ± 0.05	3.02GluThr: 3.02 ± 0.049	5.572GluVal: 5.572 ± 0.064	0.864GluTrp: 0.864 ± 0.027	0.786GluTyr: 0.786 ± 0.025	0.0GluXaa: 0.0 ± 0.0
Phe	3.778PheAla: 3.778 ± 0.058	0.249PheCys: 0.249 ± 0.015	2.171PheAsp: 2.171 ± 0.038	1.645PheGlu: 1.645 ± 0.037	0.958PhePhe: 0.958 ± 0.028	2.968PheGly: 2.968 ± 0.051	0.631PheHis: 0.631 ± 0.023	0.863PheIle: 0.863 ± 0.026	0.521PheLys: 0.521 ± 0.019	2.636PheLeu: 2.636 ± 0.051	0.454PheMet: 0.454 ± 0.019	0.594PheAsn: 0.594 ± 0.02	1.277PhePro: 1.277 ± 0.031	0.61PheGln: 0.61 ± 0.021	1.709PheArg: 1.709 ± 0.039	1.571PheSer: 1.571 ± 0.034	2.016PheThr: 2.016 ± 0.043	2.7PheVal: 2.7 ± 0.05	0.44PheTrp: 0.44 ± 0.021	0.603PheTyr: 0.603 ± 0.024	0.0PheXaa: 0.0 ± 0.0
Gly	10.221GlyAla: 10.221 ± 0.098	0.789GlyCys: 0.789 ± 0.025	5.832GlyAsp: 5.832 ± 0.075	5.106GlyGlu: 5.106 ± 0.06	3.012GlyPhe: 3.012 ± 0.06	7.888GlyGly: 7.888 ± 0.089	2.107GlyHis: 2.107 ± 0.045	3.693GlyIle: 3.693 ± 0.055	2.106GlyLys: 2.106 ± 0.043	9.367GlyLeu: 9.367 ± 0.096	1.904GlyMet: 1.904 ± 0.04	1.745GlyAsn: 1.745 ± 0.058	4.311GlyPro: 4.311 ± 0.071	2.591GlyGln: 2.591 ± 0.043	7.045GlyArg: 7.045 ± 0.08	5.569GlySer: 5.569 ± 0.069	5.84GlyThr: 5.84 ± 0.084	8.011GlyVal: 8.011 ± 0.078	1.771GlyTrp: 1.771 ± 0.039	2.087GlyTyr: 2.087 ± 0.039	0.0GlyXaa: 0.0 ± 0.0
His	2.663HisAla: 2.663 ± 0.057	0.171HisCys: 0.171 ± 0.011	1.676HisAsp: 1.676 ± 0.04	1.295HisGlu: 1.295 ± 0.035	0.6HisPhe: 0.6 ± 0.023	2.12HisGly: 2.12 ± 0.048	0.693HisHis: 0.693 ± 0.025	0.551HisIle: 0.551 ± 0.02	0.315HisLys: 0.315 ± 0.017	2.42HisLeu: 2.42 ± 0.049	0.307HisMet: 0.307 ± 0.015	0.348HisAsn: 0.348 ± 0.017	1.599HisPro: 1.599 ± 0.04	0.657HisGln: 0.657 ± 0.023	1.802HisArg: 1.802 ± 0.041	0.855HisSer: 0.855 ± 0.027	1.091HisThr: 1.091 ± 0.027	2.092HisVal: 2.092 ± 0.045	0.349HisTrp: 0.349 ± 0.017	0.452HisTyr: 0.452 ± 0.016	0.0HisXaa: 0.0 ± 0.0
Ile	5.172IleAla: 5.172 ± 0.064	0.301IleCys: 0.301 ± 0.016	2.915IleAsp: 2.915 ± 0.049	2.424IleGlu: 2.424 ± 0.046	0.84IlePhe: 0.84 ± 0.023	3.915IleGly: 3.915 ± 0.076	0.644IleHis: 0.644 ± 0.019	1.074IleIle: 1.074 ± 0.03	0.82IleLys: 0.82 ± 0.026	2.582IleLeu: 2.582 ± 0.047	0.463IleMet: 0.463 ± 0.018	0.838IleAsn: 0.838 ± 0.025	1.775IlePro: 1.775 ± 0.039	0.74IleGln: 0.74 ± 0.026	2.217IleArg: 2.217 ± 0.037	1.974IleSer: 1.974 ± 0.034	2.461IleThr: 2.461 ± 0.052	3.313IleVal: 3.313 ± 0.051	0.439IleTrp: 0.439 ± 0.018	0.595IleTyr: 0.595 ± 0.023	0.0IleXaa: 0.0 ± 0.0
Lys	2.614LysAla: 2.614 ± 0.057	0.111LysCys: 0.111 ± 0.009	1.231LysAsp: 1.231 ± 0.032	0.954LysGlu: 0.954 ± 0.03	0.488LysPhe: 0.488 ± 0.02	1.58LysGly: 1.58 ± 0.039	0.402LysHis: 0.402 ± 0.018	0.863LysIle: 0.863 ± 0.028	0.791LysLys: 0.791 ± 0.038	1.744LysLeu: 1.744 ± 0.047	0.373LysMet: 0.373 ± 0.018	0.436LysAsn: 0.436 ± 0.02	1.173LysPro: 1.173 ± 0.036	0.668LysGln: 0.668 ± 0.024	1.329LysArg: 1.329 ± 0.031	1.064LysSer: 1.064 ± 0.026	1.265LysThr: 1.265 ± 0.037	1.99LysVal: 1.99 ± 0.049	0.223LysTrp: 0.223 ± 0.013	0.409LysTyr: 0.409 ± 0.02	0.0LysXaa: 0.0 ± 0.0
Leu	14.998LeuAla: 14.998 ± 0.144	0.649LeuCys: 0.649 ± 0.021	7.337LeuAsp: 7.337 ± 0.076	5.363LeuGlu: 5.363 ± 0.075	2.44LeuPhe: 2.44 ± 0.048	9.604LeuGly: 9.604 ± 0.099	2.058LeuHis: 2.058 ± 0.043	2.925LeuIle: 2.925 ± 0.056	1.741LeuLys: 1.741 ± 0.043	10.334LeuLeu: 10.334 ± 0.126	1.723LeuMet: 1.723 ± 0.037	1.597LeuAsn: 1.597 ± 0.037	5.637LeuPro: 5.637 ± 0.066	2.169LeuGln: 2.169 ± 0.044	7.469LeuArg: 7.469 ± 0.095	5.34LeuSer: 5.34 ± 0.067	6.462LeuThr: 6.462 ± 0.088	10.781LeuVal: 10.781 ± 0.111	1.205LeuTrp: 1.205 ± 0.03	1.432LeuTyr: 1.432 ± 0.029	0.0LeuXaa: 0.0 ± 0.0
Met	2.4MetAla: 2.4 ± 0.038	0.15MetCys: 0.15 ± 0.011	0.951MetAsp: 0.951 ± 0.027	0.789MetGlu: 0.789 ± 0.026	0.548MetPhe: 0.548 ± 0.022	1.462MetGly: 1.462 ± 0.037	0.385MetHis: 0.385 ± 0.017	0.69MetIle: 0.69 ± 0.022	0.472MetLys: 0.472 ± 0.02	1.822MetLeu: 1.822 ± 0.041	0.36MetMet: 0.36 ± 0.017	0.398MetAsn: 0.398 ± 0.016	1.095MetPro: 1.095 ± 0.028	0.483MetGln: 0.483 ± 0.016	1.516MetArg: 1.516 ± 0.034	1.465MetSer: 1.465 ± 0.031	1.787MetThr: 1.787 ± 0.037	1.583MetVal: 1.583 ± 0.03	0.223MetTrp: 0.223 ± 0.013	0.282MetTyr: 0.282 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	2.25AsnAla: 2.25 ± 0.049	0.14AsnCys: 0.14 ± 0.01	1.118AsnAsp: 1.118 ± 0.034	0.899AsnGlu: 0.899 ± 0.026	0.51AsnPhe: 0.51 ± 0.019	1.767AsnGly: 1.767 ± 0.049	0.372AsnHis: 0.372 ± 0.019	0.721AsnIle: 0.721 ± 0.026	0.397AsnLys: 0.397 ± 0.019	1.776AsnLeu: 1.776 ± 0.039	0.298AsnMet: 0.298 ± 0.016	0.469AsnAsn: 0.469 ± 0.034	1.342AsnPro: 1.342 ± 0.035	0.508AsnGln: 0.508 ± 0.021	1.222AsnArg: 1.222 ± 0.029	0.812AsnSer: 0.812 ± 0.025	1.075AsnThr: 1.075 ± 0.04	1.515AsnVal: 1.515 ± 0.037	0.247AsnTrp: 0.247 ± 0.014	0.407AsnTyr: 0.407 ± 0.019	0.0AsnXaa: 0.0 ± 0.0
Pro	7.225ProAla: 7.225 ± 0.101	0.298ProCys: 0.298 ± 0.02	4.666ProAsp: 4.666 ± 0.072	3.68ProGlu: 3.68 ± 0.05	1.455ProPhe: 1.455 ± 0.033	5.456ProGly: 5.456 ± 0.069	1.164ProHis: 1.164 ± 0.033	1.735ProIle: 1.735 ± 0.036	0.946ProLys: 0.946 ± 0.03	4.643ProLeu: 4.643 ± 0.065	1.058ProMet: 1.058 ± 0.028	0.836ProAsn: 0.836 ± 0.029	2.662ProPro: 2.662 ± 0.052	1.355ProGln: 1.355 ± 0.035	3.533ProArg: 3.533 ± 0.064	3.227ProSer: 3.227 ± 0.054	3.948ProThr: 3.948 ± 0.064	5.154ProVal: 5.154 ± 0.063	0.925ProTrp: 0.925 ± 0.026	1.131ProTyr: 1.131 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	3.488GlnAla: 3.488 ± 0.043	0.155GlnCys: 0.155 ± 0.01	1.337GlnAsp: 1.337 ± 0.032	1.273GlnGlu: 1.273 ± 0.034	0.72GlnPhe: 0.72 ± 0.022	2.112GlnGly: 2.112 ± 0.035	0.692GlnHis: 0.692 ± 0.021	0.993GlnIle: 0.993 ± 0.025	0.54GlnLys: 0.54 ± 0.021	2.943GlnLeu: 2.943 ± 0.048	0.559GlnMet: 0.559 ± 0.021	0.418GlnAsn: 0.418 ± 0.02	1.574GlnPro: 1.574 ± 0.035	1.108GlnGln: 1.108 ± 0.034	2.434GlnArg: 2.434 ± 0.045	1.28GlnSer: 1.28 ± 0.03	1.43GlnThr: 1.43 ± 0.032	2.832GlnVal: 2.832 ± 0.047	0.467GlnTrp: 0.467 ± 0.018	0.433GlnTyr: 0.433 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	8.743ArgAla: 8.743 ± 0.101	0.493ArgCys: 0.493 ± 0.019	4.727ArgAsp: 4.727 ± 0.058	4.313ArgGlu: 4.313 ± 0.057	2.222ArgPhe: 2.222 ± 0.04	5.538ArgGly: 5.538 ± 0.071	1.856ArgHis: 1.856 ± 0.039	3.133ArgIle: 3.133 ± 0.045	1.386ArgLys: 1.386 ± 0.036	7.972ArgLeu: 7.972 ± 0.08	1.703ArgMet: 1.703 ± 0.035	1.31ArgAsn: 1.31 ± 0.031	4.146ArgPro: 4.146 ± 0.068	2.055ArgGln: 2.055 ± 0.041	7.074ArgArg: 7.074 ± 0.105	4.393ArgSer: 4.393 ± 0.061	4.611ArgThr: 4.611 ± 0.06	6.154ArgVal: 6.154 ± 0.07	1.345ArgTrp: 1.345 ± 0.033	1.441ArgTyr: 1.441 ± 0.033	0.0ArgXaa: 0.0 ± 0.0
Ser	6.689SerAla: 6.689 ± 0.067	0.387SerCys: 0.387 ± 0.017	3.257SerAsp: 3.257 ± 0.052	2.687SerGlu: 2.687 ± 0.048	1.814SerPhe: 1.814 ± 0.045	5.783SerGly: 5.783 ± 0.069	1.104SerHis: 1.104 ± 0.029	2.024SerIle: 2.024 ± 0.041	0.96SerLys: 0.96 ± 0.031	5.338SerLeu: 5.338 ± 0.067	1.35SerMet: 1.35 ± 0.033	0.964SerAsn: 0.964 ± 0.027	3.182SerPro: 3.182 ± 0.06	1.404SerGln: 1.404 ± 0.032	3.856SerArg: 3.856 ± 0.058	3.466SerSer: 3.466 ± 0.064	3.897SerThr: 3.897 ± 0.066	4.828SerVal: 4.828 ± 0.068	0.941SerTrp: 0.941 ± 0.03	1.281SerTyr: 1.281 ± 0.033	0.0SerXaa: 0.0 ± 0.0
Thr	7.602ThrAla: 7.602 ± 0.106	0.475ThrCys: 0.475 ± 0.027	3.969ThrAsp: 3.969 ± 0.064	3.029ThrGlu: 3.029 ± 0.047	1.979ThrPhe: 1.979 ± 0.041	6.171ThrGly: 6.171 ± 0.095	1.251ThrHis: 1.251 ± 0.029	2.528ThrIle: 2.528 ± 0.053	1.237ThrLys: 1.237 ± 0.037	5.932ThrLeu: 5.932 ± 0.065	1.175ThrMet: 1.175 ± 0.033	1.23ThrAsn: 1.23 ± 0.045	4.208ThrPro: 4.208 ± 0.07	1.531ThrGln: 1.531 ± 0.033	4.112ThrArg: 4.112 ± 0.061	4.022ThrSer: 4.022 ± 0.062	4.656ThrThr: 4.656 ± 0.081	5.827ThrVal: 5.827 ± 0.093	1.136ThrTrp: 1.136 ± 0.033	1.522ThrTyr: 1.522 ± 0.037	0.0ThrXaa: 0.0 ± 0.0
Val	12.588ValAla: 12.588 ± 0.115	0.683ValCys: 0.683 ± 0.022	6.442ValAsp: 6.442 ± 0.07	5.61ValGlu: 5.61 ± 0.074	2.551ValPhe: 2.551 ± 0.049	7.884ValGly: 7.884 ± 0.083	1.98ValHis: 1.98 ± 0.048	3.2ValIle: 3.2 ± 0.048	1.68ValLys: 1.68 ± 0.043	10.187ValLeu: 10.187 ± 0.113	1.688ValMet: 1.688 ± 0.039	1.67ValAsn: 1.67 ± 0.042	5.091ValPro: 5.091 ± 0.065	2.085ValGln: 2.085 ± 0.039	6.806ValArg: 6.806 ± 0.068	5.128ValSer: 5.128 ± 0.061	6.153ValThr: 6.153 ± 0.108	10.742ValVal: 10.742 ± 0.119	1.211ValTrp: 1.211 ± 0.033	1.398ValTyr: 1.398 ± 0.036	0.0ValXaa: 0.0 ± 0.0
Trp	1.614TrpAla: 1.614 ± 0.04	0.153TrpCys: 0.153 ± 0.011	0.938TrpAsp: 0.938 ± 0.03	0.707TrpGlu: 0.707 ± 0.021	0.572TrpPhe: 0.572 ± 0.024	1.073TrpGly: 1.073 ± 0.03	0.39TrpHis: 0.39 ± 0.017	0.58TrpIle: 0.58 ± 0.021	0.301TrpLys: 0.301 ± 0.016	1.893TrpLeu: 1.893 ± 0.042	0.322TrpMet: 0.322 ± 0.017	0.35TrpAsn: 0.35 ± 0.018	0.785TrpPro: 0.785 ± 0.027	0.563TrpGln: 0.563 ± 0.018	1.324TrpArg: 1.324 ± 0.029	1.115TrpSer: 1.115 ± 0.029	1.111TrpThr: 1.111 ± 0.03	1.274TrpVal: 1.274 ± 0.03	0.414TrpTrp: 0.414 ± 0.018	0.262TrpTyr: 0.262 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.576TyrAla: 2.576 ± 0.042	0.14TyrCys: 0.14 ± 0.009	1.641TyrAsp: 1.641 ± 0.036	0.956TyrGlu: 0.956 ± 0.027	0.622TyrPhe: 0.622 ± 0.022	1.844TyrGly: 1.844 ± 0.035	0.308TyrHis: 0.308 ± 0.014	0.489TyrIle: 0.489 ± 0.022	0.374TyrLys: 0.374 ± 0.021	1.955TyrLeu: 1.955 ± 0.038	0.22TyrMet: 0.22 ± 0.014	0.372TyrAsn: 0.372 ± 0.018	0.945TyrPro: 0.945 ± 0.029	0.487TyrGln: 0.487 ± 0.02	1.381TyrArg: 1.381 ± 0.039	0.983TyrSer: 0.983 ± 0.027	1.019TyrThr: 1.019 ± 0.029	1.827TyrVal: 1.827 ± 0.037	0.325TyrTrp: 0.325 ± 0.017	0.416TyrTyr: 0.416 ± 0.02	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4242 proteins (1384144 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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