Amino acid dipepetide frequency for Campylobacter pinnipediorum subsp. caledonicus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.534AlaAla: 3.534 ± 0.128
0.833AlaCys: 0.833 ± 0.047
3.399AlaAsp: 3.399 ± 0.091
2.89AlaGlu: 2.89 ± 0.105
3.119AlaPhe: 3.119 ± 0.08
3.913AlaGly: 3.913 ± 0.106
0.96AlaHis: 0.96 ± 0.042
6.268AlaIle: 6.268 ± 0.134
6.906AlaLys: 6.906 ± 0.146
6.489AlaLeu: 6.489 ± 0.131
1.743AlaMet: 1.743 ± 0.068
4.077AlaAsn: 4.077 ± 0.101
1.522AlaPro: 1.522 ± 0.054
1.88AlaGln: 1.88 ± 0.066
2.258AlaArg: 2.258 ± 0.07
4.109AlaSer: 4.109 ± 0.094
3.401AlaThr: 3.401 ± 0.095
3.498AlaVal: 3.498 ± 0.099
0.406AlaTrp: 0.406 ± 0.027
2.383AlaTyr: 2.383 ± 0.068
0.0AlaXaa: 0.0 ± 0.0
Cys
0.69CysAla: 0.69 ± 0.035
0.13CysCys: 0.13 ± 0.019
0.808CysAsp: 0.808 ± 0.046
0.886CysGlu: 0.886 ± 0.053
0.575CysPhe: 0.575 ± 0.033
0.886CysGly: 0.886 ± 0.05
0.251CysHis: 0.251 ± 0.037
0.914CysIle: 0.914 ± 0.04
0.831CysLys: 0.831 ± 0.045
0.821CysLeu: 0.821 ± 0.041
0.261CysMet: 0.261 ± 0.021
0.45CysAsn: 0.45 ± 0.024
0.375CysPro: 0.375 ± 0.028
0.198CysGln: 0.198 ± 0.02
0.211CysArg: 0.211 ± 0.019
0.674CysSer: 0.674 ± 0.037
0.318CysThr: 0.318 ± 0.028
0.762CysVal: 0.762 ± 0.044
0.051CysTrp: 0.051 ± 0.01
0.383CysTyr: 0.383 ± 0.027
0.0CysXaa: 0.0 ± 0.0
Asp
3.203AspAla: 3.203 ± 0.095
0.535AspCys: 0.535 ± 0.034
4.006AspAsp: 4.006 ± 0.107
5.586AspGlu: 5.586 ± 0.107
3.797AspPhe: 3.797 ± 0.09
3.656AspGly: 3.656 ± 0.101
0.61AspHis: 0.61 ± 0.033
6.935AspIle: 6.935 ± 0.125
6.182AspLys: 6.182 ± 0.122
4.925AspLeu: 4.925 ± 0.107
1.499AspMet: 1.499 ± 0.051
3.526AspAsn: 3.526 ± 0.102
1.379AspPro: 1.379 ± 0.055
0.943AspGln: 0.943 ± 0.044
1.787AspArg: 1.787 ± 0.071
3.715AspSer: 3.715 ± 0.088
2.802AspThr: 2.802 ± 0.087
3.886AspVal: 3.886 ± 0.083
0.333AspTrp: 0.333 ± 0.024
2.298AspTyr: 2.298 ± 0.07
0.0AspXaa: 0.0 ± 0.0
Glu
3.94GluAla: 3.94 ± 0.128
0.695GluCys: 0.695 ± 0.033
3.14GluAsp: 3.14 ± 0.088
3.934GluGlu: 3.934 ± 0.122
3.776GluPhe: 3.776 ± 0.088
2.5GluGly: 2.5 ± 0.083
1.031GluHis: 1.031 ± 0.046
6.847GluIle: 6.847 ± 0.13
6.514GluLys: 6.514 ± 0.151
7.605GluLeu: 7.605 ± 0.121
1.339GluMet: 1.339 ± 0.055
5.02GluAsn: 5.02 ± 0.104
1.469GluPro: 1.469 ± 0.06
2.294GluGln: 2.294 ± 0.077
2.103GluArg: 2.103 ± 0.062
3.147GluSer: 3.147 ± 0.101
2.273GluThr: 2.273 ± 0.075
3.614GluVal: 3.614 ± 0.085
0.431GluTrp: 0.431 ± 0.028
2.602GluTyr: 2.602 ± 0.07
0.0GluXaa: 0.0 ± 0.0
Phe
3.403PheAla: 3.403 ± 0.08
0.768PheCys: 0.768 ± 0.038
3.98PheAsp: 3.98 ± 0.104
3.585PheGlu: 3.585 ± 0.087
3.161PhePhe: 3.161 ± 0.109
3.766PheGly: 3.766 ± 0.095
0.568PheHis: 0.568 ± 0.033
4.99PheIle: 4.99 ± 0.102
4.637PheLys: 4.637 ± 0.101
5.458PheLeu: 5.458 ± 0.134
1.318PheMet: 1.318 ± 0.05
3.109PheAsn: 3.109 ± 0.09
0.924PhePro: 0.924 ± 0.041
0.941PheGln: 0.941 ± 0.039
1.381PheArg: 1.381 ± 0.044
3.978PheSer: 3.978 ± 0.104
2.301PheThr: 2.301 ± 0.078
3.353PheVal: 3.353 ± 0.099
0.448PheTrp: 0.448 ± 0.03
2.235PheTyr: 2.235 ± 0.08
0.0PheXaa: 0.0 ± 0.0
Gly
4.41GlyAla: 4.41 ± 0.118
0.693GlyCys: 0.693 ± 0.041
3.248GlyAsp: 3.248 ± 0.087
3.469GlyGlu: 3.469 ± 0.107
3.745GlyPhe: 3.745 ± 0.092
4.039GlyGly: 4.039 ± 0.118
0.977GlyHis: 0.977 ± 0.05
5.449GlyIle: 5.449 ± 0.121
4.845GlyLys: 4.845 ± 0.125
5.327GlyLeu: 5.327 ± 0.097
1.393GlyMet: 1.393 ± 0.058
2.644GlyAsn: 2.644 ± 0.096
0.825GlyPro: 0.825 ± 0.044
1.288GlyGln: 1.288 ± 0.059
1.905GlyArg: 1.905 ± 0.072
3.713GlySer: 3.713 ± 0.094
2.532GlyThr: 2.532 ± 0.088
4.711GlyVal: 4.711 ± 0.105
0.457GlyTrp: 0.457 ± 0.035
2.614GlyTyr: 2.614 ± 0.077
0.0GlyXaa: 0.0 ± 0.0
His
0.785HisAla: 0.785 ± 0.038
0.191HisCys: 0.191 ± 0.018
0.735HisAsp: 0.735 ± 0.043
0.764HisGlu: 0.764 ± 0.039
0.848HisPhe: 0.848 ± 0.041
0.922HisGly: 0.922 ± 0.049
0.311HisHis: 0.311 ± 0.036
1.398HisIle: 1.398 ± 0.05
1.261HisLys: 1.261 ± 0.051
1.353HisLeu: 1.353 ± 0.054
0.377HisMet: 0.377 ± 0.026
0.81HisAsn: 0.81 ± 0.04
0.653HisPro: 0.653 ± 0.042
0.41HisGln: 0.41 ± 0.03
0.442HisArg: 0.442 ± 0.034
1.038HisSer: 1.038 ± 0.046
0.8HisThr: 0.8 ± 0.043
0.606HisVal: 0.606 ± 0.029
0.109HisTrp: 0.109 ± 0.015
0.575HisTyr: 0.575 ± 0.032
0.0HisXaa: 0.0 ± 0.0
Ile
6.256IleAla: 6.256 ± 0.128
1.202IleCys: 1.202 ± 0.053
5.755IleAsp: 5.755 ± 0.113
5.344IleGlu: 5.344 ± 0.109
4.948IlePhe: 4.948 ± 0.15
5.449IleGly: 5.449 ± 0.106
1.134IleHis: 1.134 ± 0.043
7.449IleIle: 7.449 ± 0.182
9.297IleLys: 9.297 ± 0.151
8.398IleLeu: 8.398 ± 0.16
1.913IleMet: 1.913 ± 0.066
6.237IleAsn: 6.237 ± 0.145
2.423IlePro: 2.423 ± 0.079
2.667IleGln: 2.667 ± 0.076
2.593IleArg: 2.593 ± 0.075
7.318IleSer: 7.318 ± 0.145
4.363IleThr: 4.363 ± 0.104
5.357IleVal: 5.357 ± 0.102
0.558IleTrp: 0.558 ± 0.033
3.189IleTyr: 3.189 ± 0.073
0.0IleXaa: 0.0 ± 0.0
Lys
5.891LysAla: 5.891 ± 0.156
0.615LysCys: 0.615 ± 0.036
7.4LysAsp: 7.4 ± 0.148
7.731LysGlu: 7.731 ± 0.175
4.906LysPhe: 4.906 ± 0.104
4.104LysGly: 4.104 ± 0.098
1.309LysHis: 1.309 ± 0.048
9.404LysIle: 9.404 ± 0.145
8.76LysLys: 8.76 ± 0.179
7.687LysLeu: 7.687 ± 0.143
2.37LysMet: 2.37 ± 0.073
8.192LysAsn: 8.192 ± 0.155
2.479LysPro: 2.479 ± 0.077
3.528LysGln: 3.528 ± 0.087
2.865LysArg: 2.865 ± 0.066
5.934LysSer: 5.934 ± 0.113
5.039LysThr: 5.039 ± 0.108
4.628LysVal: 4.628 ± 0.104
0.472LysTrp: 0.472 ± 0.036
3.256LysTyr: 3.256 ± 0.087
0.0LysXaa: 0.0 ± 0.0
Leu
6.327LeuAla: 6.327 ± 0.123
1.059LeuCys: 1.059 ± 0.05
5.618LeuAsp: 5.618 ± 0.092
5.881LeuGlu: 5.881 ± 0.127
4.671LeuPhe: 4.671 ± 0.115
5.685LeuGly: 5.685 ± 0.117
1.276LeuHis: 1.276 ± 0.049
7.009LeuIle: 7.009 ± 0.132
10.271LeuLys: 10.271 ± 0.162
7.609LeuLeu: 7.609 ± 0.163
2.008LeuMet: 2.008 ± 0.072
7.081LeuAsn: 7.081 ± 0.155
2.961LeuPro: 2.961 ± 0.079
2.759LeuGln: 2.759 ± 0.067
3.058LeuArg: 3.058 ± 0.083
7.664LeuSer: 7.664 ± 0.141
4.031LeuThr: 4.031 ± 0.103
4.932LeuVal: 4.932 ± 0.099
0.49LeuTrp: 0.49 ± 0.034
3.134LeuTyr: 3.134 ± 0.085
0.0LeuXaa: 0.0 ± 0.0
Met
1.648MetAla: 1.648 ± 0.056
0.238MetCys: 0.238 ± 0.02
1.255MetAsp: 1.255 ± 0.045
0.861MetGlu: 0.861 ± 0.047
1.046MetPhe: 1.046 ± 0.046
1.435MetGly: 1.435 ± 0.064
0.372MetHis: 0.372 ± 0.026
2.2MetIle: 2.2 ± 0.068
2.159MetLys: 2.159 ± 0.071
2.387MetLeu: 2.387 ± 0.076
0.575MetMet: 0.575 ± 0.039
1.284MetAsn: 1.284 ± 0.05
0.994MetPro: 0.994 ± 0.047
1.16MetGln: 1.16 ± 0.047
0.791MetArg: 0.791 ± 0.043
1.804MetSer: 1.804 ± 0.06
0.823MetThr: 0.823 ± 0.042
1.316MetVal: 1.316 ± 0.056
0.139MetTrp: 0.139 ± 0.018
0.621MetTyr: 0.621 ± 0.032
0.0MetXaa: 0.0 ± 0.0
Asn
4.149AsnAla: 4.149 ± 0.089
0.429AsnCys: 0.429 ± 0.033
3.866AsnAsp: 3.866 ± 0.1
4.856AsnGlu: 4.856 ± 0.112
3.517AsnPhe: 3.517 ± 0.105
3.919AsnGly: 3.919 ± 0.103
0.831AsnHis: 0.831 ± 0.042
6.792AsnIle: 6.792 ± 0.175
6.062AsnLys: 6.062 ± 0.143
6.687AsnLeu: 6.687 ± 0.159
1.195AsnMet: 1.195 ± 0.045
4.125AsnAsn: 4.125 ± 0.131
2.206AsnPro: 2.206 ± 0.072
1.84AsnGln: 1.84 ± 0.059
1.755AsnArg: 1.755 ± 0.06
4.477AsnSer: 4.477 ± 0.111
3.38AsnThr: 3.38 ± 0.102
3.336AsnVal: 3.336 ± 0.091
0.305AsnTrp: 0.305 ± 0.022
2.077AsnTyr: 2.077 ± 0.076
0.0AsnXaa: 0.0 ± 0.0
Pro
1.429ProAla: 1.429 ± 0.056
0.248ProCys: 0.248 ± 0.021
1.625ProAsp: 1.625 ± 0.067
1.724ProGlu: 1.724 ± 0.059
1.598ProPhe: 1.598 ± 0.053
1.162ProGly: 1.162 ± 0.052
0.493ProHis: 0.493 ± 0.034
2.467ProIle: 2.467 ± 0.077
2.623ProLys: 2.623 ± 0.078
2.399ProLeu: 2.399 ± 0.077
0.627ProMet: 0.627 ± 0.037
1.777ProAsn: 1.777 ± 0.066
0.642ProPro: 0.642 ± 0.046
0.735ProGln: 0.735 ± 0.039
0.775ProArg: 0.775 ± 0.036
1.724ProSer: 1.724 ± 0.059
1.444ProThr: 1.444 ± 0.057
1.72ProVal: 1.72 ± 0.058
0.187ProTrp: 0.187 ± 0.02
1.124ProTyr: 1.124 ± 0.041
0.0ProXaa: 0.0 ± 0.0
Gln
1.957GlnAla: 1.957 ± 0.067
0.166GlnCys: 0.166 ± 0.021
1.859GlnAsp: 1.859 ± 0.065
2.107GlnGlu: 2.107 ± 0.081
0.857GlnPhe: 0.857 ± 0.039
1.36GlnGly: 1.36 ± 0.054
0.352GlnHis: 0.352 ± 0.024
2.978GlnIle: 2.978 ± 0.084
3.204GlnLys: 3.204 ± 0.083
1.827GlnLeu: 1.827 ± 0.055
0.758GlnMet: 0.758 ± 0.04
2.862GlnAsn: 2.862 ± 0.09
0.591GlnPro: 0.591 ± 0.036
0.855GlnGln: 0.855 ± 0.053
1.099GlnArg: 1.099 ± 0.045
1.8GlnSer: 1.8 ± 0.058
1.831GlnThr: 1.831 ± 0.069
1.347GlnVal: 1.347 ± 0.06
0.166GlnTrp: 0.166 ± 0.017
0.751GlnTyr: 0.751 ± 0.039
0.0GlnXaa: 0.0 ± 0.0
Arg
2.092ArgAla: 2.092 ± 0.066
0.271ArgCys: 0.271 ± 0.026
1.922ArgAsp: 1.922 ± 0.059
2.115ArgGlu: 2.115 ± 0.082
1.882ArgPhe: 1.882 ± 0.055
1.808ArgGly: 1.808 ± 0.072
0.541ArgHis: 0.541 ± 0.03
2.522ArgIle: 2.522 ± 0.065
2.427ArgLys: 2.427 ± 0.071
3.132ArgLeu: 3.132 ± 0.079
0.794ArgMet: 0.794 ± 0.041
1.608ArgAsn: 1.608 ± 0.044
0.829ArgPro: 0.829 ± 0.044
1.048ArgGln: 1.048 ± 0.039
1.12ArgArg: 1.12 ± 0.058
1.68ArgSer: 1.68 ± 0.059
1.233ArgThr: 1.233 ± 0.055
2.267ArgVal: 2.267 ± 0.068
0.221ArgTrp: 0.221 ± 0.019
1.414ArgTyr: 1.414 ± 0.052
0.0ArgXaa: 0.0 ± 0.0
Ser
4.016SerAla: 4.016 ± 0.091
0.707SerCys: 0.707 ± 0.041
4.01SerAsp: 4.01 ± 0.103
3.949SerGlu: 3.949 ± 0.098
4.01SerPhe: 4.01 ± 0.101
4.239SerGly: 4.239 ± 0.091
1.073SerHis: 1.073 ± 0.045
5.887SerIle: 5.887 ± 0.12
6.538SerLys: 6.538 ± 0.137
6.832SerLeu: 6.832 ± 0.145
1.619SerMet: 1.619 ± 0.052
4.239SerAsn: 4.239 ± 0.119
1.591SerPro: 1.591 ± 0.055
1.909SerGln: 1.909 ± 0.055
2.128SerArg: 2.128 ± 0.074
5.161SerSer: 5.161 ± 0.136
2.894SerThr: 2.894 ± 0.079
4.359SerVal: 4.359 ± 0.093
0.48SerTrp: 0.48 ± 0.036
2.69SerTyr: 2.69 ± 0.077
0.0SerXaa: 0.0 ± 0.0
Thr
2.749ThrAla: 2.749 ± 0.083
0.427ThrCys: 0.427 ± 0.03
2.482ThrAsp: 2.482 ± 0.077
2.086ThrGlu: 2.086 ± 0.072
2.12ThrPhe: 2.12 ± 0.07
2.894ThrGly: 2.894 ± 0.085
0.878ThrHis: 0.878 ± 0.04
4.052ThrIle: 4.052 ± 0.099
4.786ThrLys: 4.786 ± 0.11
4.883ThrLeu: 4.883 ± 0.108
0.97ThrMet: 0.97 ± 0.045
3.157ThrAsn: 3.157 ± 0.104
1.884ThrPro: 1.884 ± 0.062
1.804ThrGln: 1.804 ± 0.063
1.509ThrArg: 1.509 ± 0.052
3.258ThrSer: 3.258 ± 0.078
2.772ThrThr: 2.772 ± 0.107
1.913ThrVal: 1.913 ± 0.083
0.297ThrTrp: 0.297 ± 0.025
1.688ThrTyr: 1.688 ± 0.055
0.0ThrXaa: 0.0 ± 0.0
Val
4.269ValAla: 4.269 ± 0.105
0.844ValCys: 0.844 ± 0.039
3.572ValAsp: 3.572 ± 0.093
3.477ValGlu: 3.477 ± 0.084
3.187ValPhe: 3.187 ± 0.09
3.913ValGly: 3.913 ± 0.102
0.659ValHis: 0.659 ± 0.037
4.654ValIle: 4.654 ± 0.123
5.251ValLys: 5.251 ± 0.117
5.923ValLeu: 5.923 ± 0.111
1.351ValMet: 1.351 ± 0.057
3.05ValAsn: 3.05 ± 0.085
1.556ValPro: 1.556 ± 0.05
1.219ValGln: 1.219 ± 0.045
1.842ValArg: 1.842 ± 0.056
4.365ValSer: 4.365 ± 0.09
2.261ValThr: 2.261 ± 0.084
4.496ValVal: 4.496 ± 0.112
0.375ValTrp: 0.375 ± 0.03
1.968ValTyr: 1.968 ± 0.067
0.0ValXaa: 0.0 ± 0.0
Trp
0.459TrpAla: 0.459 ± 0.032
0.07TrpCys: 0.07 ± 0.01
0.421TrpAsp: 0.421 ± 0.026
0.333TrpGlu: 0.333 ± 0.024
0.33TrpPhe: 0.33 ± 0.03
0.482TrpGly: 0.482 ± 0.036
0.16TrpHis: 0.16 ± 0.019
0.537TrpIle: 0.537 ± 0.036
0.331TrpLys: 0.331 ± 0.026
0.688TrpLeu: 0.688 ± 0.04
0.225TrpMet: 0.225 ± 0.019
0.301TrpAsn: 0.301 ± 0.026
0.099TrpPro: 0.099 ± 0.016
0.255TrpGln: 0.255 ± 0.021
0.204TrpArg: 0.204 ± 0.02
0.385TrpSer: 0.385 ± 0.029
0.213TrpThr: 0.213 ± 0.022
0.398TrpVal: 0.398 ± 0.032
0.086TrpTrp: 0.086 ± 0.013
0.255TrpTyr: 0.255 ± 0.024
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.381TyrAla: 2.381 ± 0.072
0.356TyrCys: 0.356 ± 0.026
2.501TyrAsp: 2.501 ± 0.08
2.694TyrGlu: 2.694 ± 0.075
2.21TyrPhe: 2.21 ± 0.076
2.155TyrGly: 2.155 ± 0.068
0.602TyrHis: 0.602 ± 0.03
3.1TyrIle: 3.1 ± 0.075
3.685TyrLys: 3.685 ± 0.085
3.096TyrLeu: 3.096 ± 0.086
0.772TyrMet: 0.772 ± 0.035
2.252TyrAsn: 2.252 ± 0.068
1.122TyrPro: 1.122 ± 0.052
0.993TyrGln: 0.993 ± 0.047
1.099TyrArg: 1.099 ± 0.05
2.385TyrSer: 2.385 ± 0.072
1.898TyrThr: 1.898 ± 0.066
1.734TyrVal: 1.734 ± 0.053
0.223TyrTrp: 0.223 ± 0.022
1.383TyrTyr: 1.383 ± 0.055
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1649 proteins (524899 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski