Amino acid dipepetide frequency for Orf virus (strain Goat/Texas/SA00/2000) (OV-SA00) (Orf virus-San Angelo 2000)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
14.464AlaAla: 14.464 ± 1.063
2.545AlaCys: 2.545 ± 0.387
6.637AlaAsp: 6.637 ± 0.442
5.995AlaGlu: 5.995 ± 0.462
3.711AlaPhe: 3.711 ± 0.366
5.258AlaGly: 5.258 ± 0.443
1.737AlaHis: 1.737 ± 0.215
3.069AlaIle: 3.069 ± 0.319
2.95AlaLys: 2.95 ± 0.281
10.777AlaLeu: 10.777 ± 0.727
2.664AlaMet: 2.664 ± 0.282
2.593AlaAsn: 2.593 ± 0.26
5.686AlaPro: 5.686 ± 0.56
2.379AlaGln: 2.379 ± 0.223
10.206AlaArg: 10.206 ± 0.619
6.709AlaSer: 6.709 ± 0.442
4.52AlaThr: 4.52 ± 0.355
9.111AlaVal: 9.111 ± 0.604
0.547AlaTrp: 0.547 ± 0.129
2.236AlaTyr: 2.236 ± 0.27
0.0AlaXaa: 0.0 ± 0.0
Cys
2.26CysAla: 2.26 ± 0.326
0.809CysCys: 0.809 ± 0.143
1.38CysAsp: 1.38 ± 0.183
1.404CysGlu: 1.404 ± 0.191
0.928CysPhe: 0.928 ± 0.151
1.832CysGly: 1.832 ± 0.171
0.309CysHis: 0.309 ± 0.071
0.761CysIle: 0.761 ± 0.151
0.785CysLys: 0.785 ± 0.126
2.308CysLeu: 2.308 ± 0.299
0.666CysMet: 0.666 ± 0.142
0.547CysAsn: 0.547 ± 0.115
1.237CysPro: 1.237 ± 0.381
0.404CysGln: 0.404 ± 0.097
1.832CysArg: 1.832 ± 0.237
1.808CysSer: 1.808 ± 0.216
1.261CysThr: 1.261 ± 0.188
2.474CysVal: 2.474 ± 0.243
0.19CysTrp: 0.19 ± 0.059
0.714CysTyr: 0.714 ± 0.112
0.0CysXaa: 0.0 ± 0.0
Asp
7.327AspAla: 7.327 ± 0.453
1.118AspCys: 1.118 ± 0.155
3.402AspAsp: 3.402 ± 0.306
4.092AspGlu: 4.092 ± 0.28
3.045AspPhe: 3.045 ± 0.267
3.997AspGly: 3.997 ± 0.295
0.714AspHis: 0.714 ± 0.113
2.831AspIle: 2.831 ± 0.257
1.832AspLys: 1.832 ± 0.247
5.4AspLeu: 5.4 ± 0.333
1.808AspMet: 1.808 ± 0.182
2.165AspAsn: 2.165 ± 0.263
3.021AspPro: 3.021 ± 0.315
0.666AspGln: 0.666 ± 0.14
3.64AspArg: 3.64 ± 0.35
3.783AspSer: 3.783 ± 0.322
2.688AspThr: 2.688 ± 0.328
5.543AspVal: 5.543 ± 0.418
0.404AspTrp: 0.404 ± 0.096
1.689AspTyr: 1.689 ± 0.207
0.0AspXaa: 0.0 ± 0.0
Glu
4.924GluAla: 4.924 ± 0.335
0.952GluCys: 0.952 ± 0.165
3.545GluAsp: 3.545 ± 0.321
4.425GluGlu: 4.425 ± 0.444
2.974GluPhe: 2.974 ± 0.27
2.712GluGly: 2.712 ± 0.279
1.546GluHis: 1.546 ± 0.215
2.474GluIle: 2.474 ± 0.321
2.76GluLys: 2.76 ± 0.268
5.21GluLeu: 5.21 ± 0.351
1.76GluMet: 1.76 ± 0.235
2.26GluAsn: 2.26 ± 0.282
2.45GluPro: 2.45 ± 0.268
1.475GluGln: 1.475 ± 0.248
4.924GluArg: 4.924 ± 0.387
3.783GluSer: 3.783 ± 0.288
3.783GluThr: 3.783 ± 0.289
4.449GluVal: 4.449 ± 0.338
0.619GluTrp: 0.619 ± 0.103
1.832GluTyr: 1.832 ± 0.157
0.0GluXaa: 0.0 ± 0.0
Phe
4.472PheAla: 4.472 ± 0.35
1.308PheCys: 1.308 ± 0.226
2.712PheAsp: 2.712 ± 0.253
2.45PheGlu: 2.45 ± 0.281
2.403PhePhe: 2.403 ± 0.26
2.617PheGly: 2.617 ± 0.261
0.928PheHis: 0.928 ± 0.186
1.499PheIle: 1.499 ± 0.201
1.689PheLys: 1.689 ± 0.23
4.306PheLeu: 4.306 ± 0.392
1.213PheMet: 1.213 ± 0.183
1.879PheAsn: 1.879 ± 0.191
1.975PhePro: 1.975 ± 0.179
0.928PheGln: 0.928 ± 0.143
2.974PheArg: 2.974 ± 0.245
3.545PheSer: 3.545 ± 0.277
2.26PheThr: 2.26 ± 0.232
4.52PheVal: 4.52 ± 0.375
0.428PheTrp: 0.428 ± 0.11
1.166PheTyr: 1.166 ± 0.171
0.0PheXaa: 0.0 ± 0.0
Gly
6.899GlyAla: 6.899 ± 0.496
1.475GlyCys: 1.475 ± 0.2
3.521GlyAsp: 3.521 ± 0.289
2.95GlyGlu: 2.95 ± 0.251
2.403GlyPhe: 2.403 ± 0.259
3.997GlyGly: 3.997 ± 0.396
0.88GlyHis: 0.88 ± 0.129
2.189GlyIle: 2.189 ± 0.257
2.212GlyLys: 2.212 ± 0.238
4.068GlyLeu: 4.068 ± 0.314
1.427GlyMet: 1.427 ± 0.199
1.784GlyAsn: 1.784 ± 0.229
1.737GlyPro: 1.737 ± 0.27
1.047GlyGln: 1.047 ± 0.175
4.734GlyArg: 4.734 ± 0.387
3.521GlySer: 3.521 ± 0.254
2.831GlyThr: 2.831 ± 0.352
5.091GlyVal: 5.091 ± 0.403
0.476GlyTrp: 0.476 ± 0.089
1.618GlyTyr: 1.618 ± 0.216
0.0GlyXaa: 0.0 ± 0.0
His
1.951HisAla: 1.951 ± 0.21
0.5HisCys: 0.5 ± 0.105
1.118HisAsp: 1.118 ± 0.166
0.88HisGlu: 0.88 ± 0.159
0.856HisPhe: 0.856 ± 0.127
1.189HisGly: 1.189 ± 0.162
0.833HisHis: 0.833 ± 0.156
1.094HisIle: 1.094 ± 0.155
0.69HisLys: 0.69 ± 0.148
2.189HisLeu: 2.189 ± 0.233
0.714HisMet: 0.714 ± 0.123
0.642HisAsn: 0.642 ± 0.108
1.237HisPro: 1.237 ± 0.159
0.404HisGln: 0.404 ± 0.089
1.808HisArg: 1.808 ± 0.225
1.213HisSer: 1.213 ± 0.181
1.261HisThr: 1.261 ± 0.161
2.403HisVal: 2.403 ± 0.277
0.214HisTrp: 0.214 ± 0.078
0.571HisTyr: 0.571 ± 0.088
0.0HisXaa: 0.0 ± 0.0
Ile
3.331IleAla: 3.331 ± 0.283
1.071IleCys: 1.071 ± 0.145
2.236IleAsp: 2.236 ± 0.216
2.498IleGlu: 2.498 ± 0.226
2.07IlePhe: 2.07 ± 0.23
1.451IleGly: 1.451 ± 0.212
0.714IleHis: 0.714 ± 0.136
1.308IleIle: 1.308 ± 0.199
1.689IleLys: 1.689 ± 0.225
2.95IleLeu: 2.95 ± 0.318
1.047IleMet: 1.047 ± 0.173
1.927IleAsn: 1.927 ± 0.244
1.713IlePro: 1.713 ± 0.247
1.047IleGln: 1.047 ± 0.163
2.736IleArg: 2.736 ± 0.285
2.902IleSer: 2.902 ± 0.367
1.808IleThr: 1.808 ± 0.213
3.687IleVal: 3.687 ± 0.344
0.262IleTrp: 0.262 ± 0.086
1.332IleTyr: 1.332 ± 0.164
0.0IleXaa: 0.0 ± 0.0
Lys
2.117LysAla: 2.117 ± 0.224
0.619LysCys: 0.619 ± 0.127
2.07LysAsp: 2.07 ± 0.223
1.998LysGlu: 1.998 ± 0.229
1.356LysPhe: 1.356 ± 0.239
1.451LysGly: 1.451 ± 0.175
0.975LysHis: 0.975 ± 0.149
2.26LysIle: 2.26 ± 0.331
2.308LysLys: 2.308 ± 0.273
3.83LysLeu: 3.83 ± 0.336
1.047LysMet: 1.047 ± 0.153
1.57LysAsn: 1.57 ± 0.23
1.546LysPro: 1.546 ± 0.214
1.023LysGln: 1.023 ± 0.191
2.593LysArg: 2.593 ± 0.292
2.641LysSer: 2.641 ± 0.247
2.688LysThr: 2.688 ± 0.274
2.331LysVal: 2.331 ± 0.25
0.119LysTrp: 0.119 ± 0.065
1.356LysTyr: 1.356 ± 0.19
0.0LysXaa: 0.0 ± 0.0
Leu
9.801LeuAla: 9.801 ± 0.656
2.545LeuCys: 2.545 ± 0.238
5.662LeuAsp: 5.662 ± 0.417
5.258LeuGlu: 5.258 ± 0.384
4.71LeuPhe: 4.71 ± 0.348
4.829LeuGly: 4.829 ± 0.323
2.212LeuHis: 2.212 ± 0.299
3.568LeuIle: 3.568 ± 0.267
3.402LeuLys: 3.402 ± 0.297
9.992LeuLeu: 9.992 ± 0.557
2.926LeuMet: 2.926 ± 0.264
2.974LeuAsn: 2.974 ± 0.328
4.044LeuPro: 4.044 ± 0.299
1.951LeuGln: 1.951 ± 0.249
8.683LeuArg: 8.683 ± 0.586
6.97LeuSer: 6.97 ± 0.361
5.043LeuThr: 5.043 ± 0.392
8.136LeuVal: 8.136 ± 0.482
0.452LeuTrp: 0.452 ± 0.116
2.688LeuTyr: 2.688 ± 0.276
0.0LeuXaa: 0.0 ± 0.0
Met
2.783MetAla: 2.783 ± 0.248
0.523MetCys: 0.523 ± 0.134
2.022MetAsp: 2.022 ± 0.219
2.022MetGlu: 2.022 ± 0.219
1.427MetPhe: 1.427 ± 0.179
1.237MetGly: 1.237 ± 0.126
0.547MetHis: 0.547 ± 0.13
1.213MetIle: 1.213 ± 0.161
0.999MetLys: 0.999 ± 0.166
2.617MetLeu: 2.617 ± 0.241
0.5MetMet: 0.5 ± 0.108
0.714MetAsn: 0.714 ± 0.147
1.285MetPro: 1.285 ± 0.191
0.571MetGln: 0.571 ± 0.114
2.545MetArg: 2.545 ± 0.23
2.236MetSer: 2.236 ± 0.242
1.737MetThr: 1.737 ± 0.214
1.879MetVal: 1.879 ± 0.212
0.285MetTrp: 0.285 ± 0.074
1.142MetTyr: 1.142 ± 0.173
0.0MetXaa: 0.0 ± 0.0
Asn
3.402AsnAla: 3.402 ± 0.297
0.642AsnCys: 0.642 ± 0.134
1.665AsnAsp: 1.665 ± 0.215
1.594AsnGlu: 1.594 ± 0.187
1.975AsnPhe: 1.975 ± 0.253
1.998AsnGly: 1.998 ± 0.207
0.761AsnHis: 0.761 ± 0.159
1.808AsnIle: 1.808 ± 0.237
1.404AsnLys: 1.404 ± 0.192
2.617AsnLeu: 2.617 ± 0.309
1.261AsnMet: 1.261 ± 0.211
1.832AsnAsn: 1.832 ± 0.278
1.594AsnPro: 1.594 ± 0.198
0.666AsnGln: 0.666 ± 0.161
2.212AsnArg: 2.212 ± 0.213
2.093AsnSer: 2.093 ± 0.242
2.141AsnThr: 2.141 ± 0.228
3.426AsnVal: 3.426 ± 0.274
0.143AsnTrp: 0.143 ± 0.06
1.308AsnTyr: 1.308 ± 0.173
0.0AsnXaa: 0.0 ± 0.0
Pro
6.114ProAla: 6.114 ± 0.772
1.237ProCys: 1.237 ± 0.147
3.235ProAsp: 3.235 ± 0.247
3.664ProGlu: 3.664 ± 0.343
1.594ProPhe: 1.594 ± 0.201
3.116ProGly: 3.116 ± 0.28
0.999ProHis: 0.999 ± 0.177
1.356ProIle: 1.356 ± 0.177
1.237ProLys: 1.237 ± 0.207
4.782ProLeu: 4.782 ± 0.452
1.071ProMet: 1.071 ± 0.157
1.189ProAsn: 1.189 ± 0.181
3.973ProPro: 3.973 ± 0.48
1.166ProGln: 1.166 ± 0.175
3.64ProArg: 3.64 ± 0.341
3.949ProSer: 3.949 ± 0.356
2.569ProThr: 2.569 ± 0.362
3.64ProVal: 3.64 ± 0.321
0.404ProTrp: 0.404 ± 0.101
0.952ProTyr: 0.952 ± 0.156
0.0ProXaa: 0.0 ± 0.0
Gln
1.546GlnAla: 1.546 ± 0.203
0.476GlnCys: 0.476 ± 0.096
1.047GlnAsp: 1.047 ± 0.153
1.427GlnGlu: 1.427 ± 0.198
0.952GlnPhe: 0.952 ± 0.17
0.856GlnGly: 0.856 ± 0.154
0.761GlnHis: 0.761 ± 0.13
0.928GlnIle: 0.928 ± 0.157
0.833GlnLys: 0.833 ± 0.169
2.141GlnLeu: 2.141 ± 0.221
0.809GlnMet: 0.809 ± 0.158
0.88GlnAsn: 0.88 ± 0.15
1.332GlnPro: 1.332 ± 0.212
0.452GlnGln: 0.452 ± 0.094
1.927GlnArg: 1.927 ± 0.229
1.475GlnSer: 1.475 ± 0.22
1.475GlnThr: 1.475 ± 0.206
1.189GlnVal: 1.189 ± 0.148
0.214GlnTrp: 0.214 ± 0.071
0.571GlnTyr: 0.571 ± 0.119
0.0GlnXaa: 0.0 ± 0.0
Arg
9.111ArgAla: 9.111 ± 0.623
1.927ArgCys: 1.927 ± 0.243
4.068ArgAsp: 4.068 ± 0.312
4.663ArgGlu: 4.663 ± 0.343
3.521ArgPhe: 3.521 ± 0.33
4.615ArgGly: 4.615 ± 0.372
2.783ArgHis: 2.783 ± 0.266
2.569ArgIle: 2.569 ± 0.232
2.76ArgLys: 2.76 ± 0.264
8.017ArgLeu: 8.017 ± 0.449
2.45ArgMet: 2.45 ± 0.216
2.498ArgAsn: 2.498 ± 0.21
3.664ArgPro: 3.664 ± 0.318
2.046ArgGln: 2.046 ± 0.194
7.874ArgArg: 7.874 ± 0.616
5.21ArgSer: 5.21 ± 0.446
3.878ArgThr: 3.878 ± 0.26
7.636ArgVal: 7.636 ± 0.416
0.404ArgTrp: 0.404 ± 0.102
2.308ArgTyr: 2.308 ± 0.231
0.0ArgXaa: 0.0 ± 0.0
Ser
7.446SerAla: 7.446 ± 0.472
1.38SerCys: 1.38 ± 0.174
3.735SerAsp: 3.735 ± 0.288
3.878SerGlu: 3.878 ± 0.355
2.474SerPhe: 2.474 ± 0.25
4.449SerGly: 4.449 ± 0.407
1.166SerHis: 1.166 ± 0.169
2.712SerIle: 2.712 ± 0.291
2.664SerLys: 2.664 ± 0.284
6.495SerLeu: 6.495 ± 0.33
2.141SerMet: 2.141 ± 0.205
2.117SerAsn: 2.117 ± 0.247
3.545SerPro: 3.545 ± 0.318
1.499SerGln: 1.499 ± 0.216
5.424SerArg: 5.424 ± 0.393
5.638SerSer: 5.638 ± 0.826
4.377SerThr: 4.377 ± 0.373
6.542SerVal: 6.542 ± 0.314
0.381SerTrp: 0.381 ± 0.09
1.737SerTyr: 1.737 ± 0.209
0.0SerXaa: 0.0 ± 0.0
Thr
4.806ThrAla: 4.806 ± 0.343
1.023ThrCys: 1.023 ± 0.146
2.95ThrAsp: 2.95 ± 0.228
3.069ThrGlu: 3.069 ± 0.326
2.141ThrPhe: 2.141 ± 0.25
2.855ThrGly: 2.855 ± 0.326
1.285ThrHis: 1.285 ± 0.195
1.618ThrIle: 1.618 ± 0.236
1.879ThrLys: 1.879 ± 0.238
5.4ThrLeu: 5.4 ± 0.353
1.213ThrMet: 1.213 ± 0.164
2.117ThrAsn: 2.117 ± 0.191
4.401ThrPro: 4.401 ± 0.537
1.38ThrGln: 1.38 ± 0.23
4.258ThrArg: 4.258 ± 0.319
3.687ThrSer: 3.687 ± 0.373
3.212ThrThr: 3.212 ± 0.442
4.52ThrVal: 4.52 ± 0.358
0.381ThrTrp: 0.381 ± 0.087
1.546ThrTyr: 1.546 ± 0.198
0.0ThrXaa: 0.0 ± 0.0
Val
7.827ValAla: 7.827 ± 0.445
2.831ValCys: 2.831 ± 0.288
6.138ValAsp: 6.138 ± 0.388
4.806ValGlu: 4.806 ± 0.35
4.449ValPhe: 4.449 ± 0.407
4.068ValGly: 4.068 ± 0.277
1.951ValHis: 1.951 ± 0.23
2.664ValIle: 2.664 ± 0.286
2.783ValLys: 2.783 ± 0.272
9.302ValLeu: 9.302 ± 0.578
2.284ValMet: 2.284 ± 0.206
3.426ValAsn: 3.426 ± 0.299
3.902ValPro: 3.902 ± 0.274
1.57ValGln: 1.57 ± 0.175
7.47ValArg: 7.47 ± 0.379
6.304ValSer: 6.304 ± 0.415
4.425ValThr: 4.425 ± 0.34
7.827ValVal: 7.827 ± 0.508
0.642ValTrp: 0.642 ± 0.167
2.879ValTyr: 2.879 ± 0.335
0.0ValXaa: 0.0 ± 0.0
Trp
0.5TrpAla: 0.5 ± 0.083
0.167TrpCys: 0.167 ± 0.056
0.285TrpAsp: 0.285 ± 0.087
0.285TrpGlu: 0.285 ± 0.097
0.523TrpPhe: 0.523 ± 0.118
0.547TrpGly: 0.547 ± 0.131
0.119TrpHis: 0.119 ± 0.049
0.381TrpIle: 0.381 ± 0.095
0.143TrpLys: 0.143 ± 0.068
0.714TrpLeu: 0.714 ± 0.142
0.238TrpMet: 0.238 ± 0.072
0.167TrpAsn: 0.167 ± 0.081
0.333TrpPro: 0.333 ± 0.083
0.095TrpGln: 0.095 ± 0.037
0.642TrpArg: 0.642 ± 0.116
0.476TrpSer: 0.476 ± 0.102
0.523TrpThr: 0.523 ± 0.105
0.357TrpVal: 0.357 ± 0.083
0.143TrpTrp: 0.143 ± 0.1
0.285TrpTyr: 0.285 ± 0.084
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.712TyrAla: 2.712 ± 0.267
0.761TyrCys: 0.761 ± 0.133
1.737TyrAsp: 1.737 ± 0.182
1.499TyrGlu: 1.499 ± 0.207
1.76TyrPhe: 1.76 ± 0.193
1.784TyrGly: 1.784 ± 0.219
0.547TyrHis: 0.547 ± 0.102
1.475TyrIle: 1.475 ± 0.188
0.88TyrLys: 0.88 ± 0.164
2.736TyrLeu: 2.736 ± 0.235
1.023TyrMet: 1.023 ± 0.153
1.261TyrAsn: 1.261 ± 0.24
1.213TyrPro: 1.213 ± 0.164
0.523TyrGln: 0.523 ± 0.124
1.879TyrArg: 1.879 ± 0.225
1.856TyrSer: 1.856 ± 0.225
1.261TyrThr: 1.261 ± 0.154
2.807TyrVal: 2.807 ± 0.263
0.214TyrTrp: 0.214 ± 0.071
0.904TyrTyr: 0.904 ± 0.143
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 129 proteins (42036 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski