Amino acid dipepetide frequency for Palleronia marisminoris

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.0AlaAla: 17.0 ± 0.189	1.091AlaCys: 1.091 ± 0.034	7.155AlaAsp: 7.155 ± 0.083	8.815AlaGlu: 8.815 ± 0.1	4.422AlaPhe: 4.422 ± 0.068	10.929AlaGly: 10.929 ± 0.119	2.287AlaHis: 2.287 ± 0.05	6.138AlaIle: 6.138 ± 0.083	3.129AlaLys: 3.129 ± 0.055	13.617AlaLeu: 13.617 ± 0.123	3.659AlaMet: 3.659 ± 0.065	2.487AlaAsn: 2.487 ± 0.046	5.959AlaPro: 5.959 ± 0.094	4.074AlaGln: 4.074 ± 0.064	9.451AlaArg: 9.451 ± 0.106	5.471AlaSer: 5.471 ± 0.082	6.355AlaThr: 6.355 ± 0.085	8.662AlaVal: 8.662 ± 0.104	1.633AlaTrp: 1.633 ± 0.043	2.379AlaTyr: 2.379 ± 0.045	0.0AlaXaa: 0.0 ± 0.0
Cys	1.001CysAla: 1.001 ± 0.031	0.11CysCys: 0.11 ± 0.01	0.592CysAsp: 0.592 ± 0.025	0.466CysGlu: 0.466 ± 0.02	0.298CysPhe: 0.298 ± 0.017	0.905CysGly: 0.905 ± 0.033	0.237CysHis: 0.237 ± 0.015	0.38CysIle: 0.38 ± 0.019	0.155CysLys: 0.155 ± 0.011	0.899CysLeu: 0.899 ± 0.031	0.167CysMet: 0.167 ± 0.011	0.208CysAsn: 0.208 ± 0.014	0.464CysPro: 0.464 ± 0.023	0.202CysGln: 0.202 ± 0.012	0.595CysArg: 0.595 ± 0.022	0.439CysSer: 0.439 ± 0.02	0.403CysThr: 0.403 ± 0.018	0.622CysVal: 0.622 ± 0.027	0.119CysTrp: 0.119 ± 0.011	0.176CysTyr: 0.176 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	7.832AspAla: 7.832 ± 0.097	0.472AspCys: 0.472 ± 0.021	3.765AspAsp: 3.765 ± 0.087	4.257AspGlu: 4.257 ± 0.069	2.11AspPhe: 2.11 ± 0.046	5.847AspGly: 5.847 ± 0.099	1.385AspHis: 1.385 ± 0.033	2.889AspIle: 2.889 ± 0.051	1.359AspLys: 1.359 ± 0.039	6.622AspLeu: 6.622 ± 0.085	1.606AspMet: 1.606 ± 0.037	1.158AspAsn: 1.158 ± 0.032	3.953AspPro: 3.953 ± 0.057	1.775AspGln: 1.775 ± 0.043	5.22AspArg: 5.22 ± 0.085	2.119AspSer: 2.119 ± 0.045	3.08AspThr: 3.08 ± 0.067	4.507AspVal: 4.507 ± 0.069	1.235AspTrp: 1.235 ± 0.035	1.476AspTyr: 1.476 ± 0.033	0.0AspXaa: 0.0 ± 0.0
Glu	8.797GluAla: 8.797 ± 0.103	0.373GluCys: 0.373 ± 0.017	3.74GluAsp: 3.74 ± 0.07	3.74GluGlu: 3.74 ± 0.072	1.714GluPhe: 1.714 ± 0.044	5.554GluGly: 5.554 ± 0.082	1.216GluHis: 1.216 ± 0.031	3.724GluIle: 3.724 ± 0.053	1.761GluLys: 1.761 ± 0.051	5.281GluLeu: 5.281 ± 0.071	1.942GluMet: 1.942 ± 0.041	1.626GluAsn: 1.626 ± 0.038	2.909GluPro: 2.909 ± 0.055	1.91GluGln: 1.91 ± 0.046	5.036GluArg: 5.036 ± 0.069	2.435GluSer: 2.435 ± 0.045	4.141GluThr: 4.141 ± 0.053	4.718GluVal: 4.718 ± 0.074	0.745GluTrp: 0.745 ± 0.03	0.957GluTyr: 0.957 ± 0.031	0.0GluXaa: 0.0 ± 0.0
Phe	4.475PheAla: 4.475 ± 0.07	0.394PheCys: 0.394 ± 0.018	2.877PheAsp: 2.877 ± 0.05	2.154PheGlu: 2.154 ± 0.047	1.429PhePhe: 1.429 ± 0.039	3.683PheGly: 3.683 ± 0.057	0.741PheHis: 0.741 ± 0.026	1.535PheIle: 1.535 ± 0.039	0.707PheLys: 0.707 ± 0.025	3.381PheLeu: 3.381 ± 0.069	0.78PheMet: 0.78 ± 0.03	0.899PheAsn: 0.899 ± 0.034	1.643PhePro: 1.643 ± 0.04	0.937PheGln: 0.937 ± 0.031	2.317PheArg: 2.317 ± 0.05	1.9PheSer: 1.9 ± 0.048	1.99PheThr: 1.99 ± 0.041	2.719PheVal: 2.719 ± 0.055	0.536PheTrp: 0.536 ± 0.026	0.867PheTyr: 0.867 ± 0.032	0.0PheXaa: 0.0 ± 0.0
Gly	10.259GlyAla: 10.259 ± 0.12	0.882GlyCys: 0.882 ± 0.036	5.001GlyAsp: 5.001 ± 0.098	5.198GlyGlu: 5.198 ± 0.078	3.53GlyPhe: 3.53 ± 0.065	7.736GlyGly: 7.736 ± 0.12	1.973GlyHis: 1.973 ± 0.047	4.569GlyIle: 4.569 ± 0.077	2.569GlyLys: 2.569 ± 0.061	9.172GlyLeu: 9.172 ± 0.119	2.598GlyMet: 2.598 ± 0.05	2.004GlyAsn: 2.004 ± 0.067	4.011GlyPro: 4.011 ± 0.069	3.0GlyGln: 3.0 ± 0.056	6.683GlyArg: 6.683 ± 0.08	4.4GlySer: 4.4 ± 0.063	5.134GlyThr: 5.134 ± 0.076	6.5GlyVal: 6.5 ± 0.079	1.463GlyTrp: 1.463 ± 0.039	2.244GlyTyr: 2.244 ± 0.045	0.0GlyXaa: 0.0 ± 0.0
His	2.5HisAla: 2.5 ± 0.057	0.208HisCys: 0.208 ± 0.013	1.397HisAsp: 1.397 ± 0.039	1.227HisGlu: 1.227 ± 0.031	0.744HisPhe: 0.744 ± 0.023	2.002HisGly: 2.002 ± 0.043	0.551HisHis: 0.551 ± 0.023	0.872HisIle: 0.872 ± 0.03	0.429HisLys: 0.429 ± 0.019	2.038HisLeu: 2.038 ± 0.048	0.553HisMet: 0.553 ± 0.022	0.402HisAsn: 0.402 ± 0.02	1.385HisPro: 1.385 ± 0.038	0.547HisGln: 0.547 ± 0.021	1.515HisArg: 1.515 ± 0.041	0.831HisSer: 0.831 ± 0.028	0.804HisThr: 0.804 ± 0.027	1.688HisVal: 1.688 ± 0.034	0.34HisTrp: 0.34 ± 0.017	0.501HisTyr: 0.501 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	6.92IleAla: 6.92 ± 0.08	0.559IleCys: 0.559 ± 0.022	3.615IleAsp: 3.615 ± 0.056	3.662IleGlu: 3.662 ± 0.062	1.765IlePhe: 1.765 ± 0.042	4.876IleGly: 4.876 ± 0.068	0.958IleHis: 0.958 ± 0.031	1.949IleIle: 1.949 ± 0.05	1.003IleLys: 1.003 ± 0.03	4.978IleLeu: 4.978 ± 0.078	0.979IleMet: 0.979 ± 0.031	1.075IleAsn: 1.075 ± 0.031	2.278IlePro: 2.278 ± 0.045	1.123IleGln: 1.123 ± 0.033	3.35IleArg: 3.35 ± 0.055	2.661IleSer: 2.661 ± 0.046	2.518IleThr: 2.518 ± 0.052	4.133IleVal: 4.133 ± 0.062	0.644IleTrp: 0.644 ± 0.026	1.17IleTyr: 1.17 ± 0.031	0.0IleXaa: 0.0 ± 0.0
Lys	3.107LysAla: 3.107 ± 0.062	0.133LysCys: 0.133 ± 0.01	1.472LysAsp: 1.472 ± 0.039	1.341LysGlu: 1.341 ± 0.039	0.735LysPhe: 0.735 ± 0.027	2.318LysGly: 2.318 ± 0.061	0.523LysHis: 0.523 ± 0.021	1.386LysIle: 1.386 ± 0.04	0.959LysLys: 0.959 ± 0.042	2.426LysLeu: 2.426 ± 0.053	0.677LysMet: 0.677 ± 0.027	0.658LysAsn: 0.658 ± 0.024	1.518LysPro: 1.518 ± 0.039	0.678LysGln: 0.678 ± 0.026	2.013LysArg: 2.013 ± 0.047	1.449LysSer: 1.449 ± 0.037	1.492LysThr: 1.492 ± 0.038	1.935LysVal: 1.935 ± 0.043	0.304LysTrp: 0.304 ± 0.017	0.465LysTyr: 0.465 ± 0.023	0.0LysXaa: 0.0 ± 0.0
Leu	12.999LeuAla: 12.999 ± 0.141	0.93LeuCys: 0.93 ± 0.034	6.419LeuAsp: 6.419 ± 0.083	5.207LeuGlu: 5.207 ± 0.071	3.421LeuPhe: 3.421 ± 0.062	8.804LeuGly: 8.804 ± 0.105	1.914LeuHis: 1.914 ± 0.047	4.91LeuIle: 4.91 ± 0.088	2.652LeuLys: 2.652 ± 0.052	8.861LeuLeu: 8.861 ± 0.108	2.493LeuMet: 2.493 ± 0.051	2.429LeuAsn: 2.429 ± 0.05	5.584LeuPro: 5.584 ± 0.085	2.523LeuGln: 2.523 ± 0.048	7.32LeuArg: 7.32 ± 0.089	6.905LeuSer: 6.905 ± 0.083	6.066LeuThr: 6.066 ± 0.074	7.245LeuVal: 7.245 ± 0.093	1.299LeuTrp: 1.299 ± 0.033	1.959LeuTyr: 1.959 ± 0.042	0.0LeuXaa: 0.0 ± 0.0
Met	3.275MetAla: 3.275 ± 0.058	0.19MetCys: 0.19 ± 0.014	1.352MetAsp: 1.352 ± 0.035	1.333MetGlu: 1.333 ± 0.032	0.777MetPhe: 0.777 ± 0.03	2.223MetGly: 2.223 ± 0.045	0.453MetHis: 0.453 ± 0.018	1.477MetIle: 1.477 ± 0.032	0.927MetLys: 0.927 ± 0.03	2.545MetLeu: 2.545 ± 0.046	0.691MetMet: 0.691 ± 0.027	0.796MetAsn: 0.796 ± 0.027	1.55MetPro: 1.55 ± 0.034	0.894MetGln: 0.894 ± 0.028	1.985MetArg: 1.985 ± 0.043	1.734MetSer: 1.734 ± 0.041	2.071MetThr: 2.071 ± 0.037	1.726MetVal: 1.726 ± 0.044	0.263MetTrp: 0.263 ± 0.016	0.306MetTyr: 0.306 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	2.872AsnAla: 2.872 ± 0.054	0.206AsnCys: 0.206 ± 0.013	1.367AsnAsp: 1.367 ± 0.048	1.232AsnGlu: 1.232 ± 0.033	0.918AsnPhe: 0.918 ± 0.029	2.09AsnGly: 2.09 ± 0.05	0.506AsnHis: 0.506 ± 0.023	1.188AsnIle: 1.188 ± 0.037	0.49AsnLys: 0.49 ± 0.02	2.374AsnLeu: 2.374 ± 0.043	0.579AsnMet: 0.579 ± 0.025	0.556AsnAsn: 0.556 ± 0.027	1.671AsnPro: 1.671 ± 0.039	0.669AsnGln: 0.669 ± 0.024	1.73AsnArg: 1.73 ± 0.043	1.008AsnSer: 1.008 ± 0.032	1.131AsnThr: 1.131 ± 0.033	1.797AsnVal: 1.797 ± 0.045	0.386AsnTrp: 0.386 ± 0.017	0.573AsnTyr: 0.573 ± 0.022	0.0AsnXaa: 0.0 ± 0.0
Pro	5.987ProAla: 5.987 ± 0.093	0.346ProCys: 0.346 ± 0.016	4.409ProAsp: 4.409 ± 0.067	4.37ProGlu: 4.37 ± 0.072	1.997ProPhe: 1.997 ± 0.045	4.702ProGly: 4.702 ± 0.069	1.07ProHis: 1.07 ± 0.031	2.258ProIle: 2.258 ± 0.042	1.43ProLys: 1.43 ± 0.043	4.759ProLeu: 4.759 ± 0.064	1.281ProMet: 1.281 ± 0.034	1.206ProAsn: 1.206 ± 0.033	2.558ProPro: 2.558 ± 0.066	1.602ProGln: 1.602 ± 0.044	3.155ProArg: 3.155 ± 0.059	2.652ProSer: 2.652 ± 0.048	2.575ProThr: 2.575 ± 0.051	4.284ProVal: 4.284 ± 0.059	0.715ProTrp: 0.715 ± 0.03	1.144ProTyr: 1.144 ± 0.036	0.0ProXaa: 0.0 ± 0.0
Gln	3.627GlnAla: 3.627 ± 0.06	0.179GlnCys: 0.179 ± 0.012	1.642GlnAsp: 1.642 ± 0.037	1.58GlnGlu: 1.58 ± 0.041	0.951GlnPhe: 0.951 ± 0.03	2.547GlnGly: 2.547 ± 0.047	0.555GlnHis: 0.555 ± 0.023	1.846GlnIle: 1.846 ± 0.044	0.911GlnLys: 0.911 ± 0.028	2.578GlnLeu: 2.578 ± 0.049	0.939GlnMet: 0.939 ± 0.03	0.839GlnAsn: 0.839 ± 0.029	1.609GlnPro: 1.609 ± 0.037	1.084GlnGln: 1.084 ± 0.041	2.142GlnArg: 2.142 ± 0.05	1.65GlnSer: 1.65 ± 0.039	1.656GlnThr: 1.656 ± 0.041	2.302GlnVal: 2.302 ± 0.041	0.407GlnTrp: 0.407 ± 0.022	0.526GlnTyr: 0.526 ± 0.023	0.0GlnXaa: 0.0 ± 0.0
Arg	8.705ArgAla: 8.705 ± 0.091	0.497ArgCys: 0.497 ± 0.023	4.761ArgAsp: 4.761 ± 0.07	4.382ArgGlu: 4.382 ± 0.073	2.757ArgPhe: 2.757 ± 0.05	5.193ArgGly: 5.193 ± 0.075	1.727ArgHis: 1.727 ± 0.041	4.257ArgIle: 4.257 ± 0.06	2.036ArgLys: 2.036 ± 0.051	8.029ArgLeu: 8.029 ± 0.094	2.171ArgMet: 2.171 ± 0.046	1.774ArgAsn: 1.774 ± 0.037	3.744ArgPro: 3.744 ± 0.059	2.386ArgGln: 2.386 ± 0.051	5.855ArgArg: 5.855 ± 0.097	3.552ArgSer: 3.552 ± 0.057	3.592ArgThr: 3.592 ± 0.055	5.358ArgVal: 5.358 ± 0.066	0.954ArgTrp: 0.954 ± 0.036	1.552ArgTyr: 1.552 ± 0.041	0.0ArgXaa: 0.0 ± 0.0
Ser	5.795SerAla: 5.795 ± 0.08	0.397SerCys: 0.397 ± 0.019	3.345SerAsp: 3.345 ± 0.062	3.013SerGlu: 3.013 ± 0.052	2.129SerPhe: 2.129 ± 0.048	5.276SerGly: 5.276 ± 0.089	1.067SerHis: 1.067 ± 0.036	2.473SerIle: 2.473 ± 0.052	1.216SerLys: 1.216 ± 0.033	4.908SerLeu: 4.908 ± 0.074	1.35SerMet: 1.35 ± 0.035	1.219SerAsn: 1.219 ± 0.037	2.604SerPro: 2.604 ± 0.047	1.501SerGln: 1.501 ± 0.04	3.576SerArg: 3.576 ± 0.052	2.522SerSer: 2.522 ± 0.057	2.588SerThr: 2.588 ± 0.048	3.705SerVal: 3.705 ± 0.062	0.683SerTrp: 0.683 ± 0.029	1.265SerTyr: 1.265 ± 0.032	0.0SerXaa: 0.0 ± 0.0
Thr	6.304ThrAla: 6.304 ± 0.075	0.495ThrCys: 0.495 ± 0.024	3.252ThrAsp: 3.252 ± 0.053	3.261ThrGlu: 3.261 ± 0.049	2.059ThrPhe: 2.059 ± 0.043	5.496ThrGly: 5.496 ± 0.073	1.133ThrHis: 1.133 ± 0.034	2.739ThrIle: 2.739 ± 0.057	1.216ThrLys: 1.216 ± 0.037	6.129ThrLeu: 6.129 ± 0.085	1.317ThrMet: 1.317 ± 0.034	1.209ThrAsn: 1.209 ± 0.034	3.394ThrPro: 3.394 ± 0.059	1.441ThrGln: 1.441 ± 0.033	3.793ThrArg: 3.793 ± 0.055	2.753ThrSer: 2.753 ± 0.053	2.911ThrThr: 2.911 ± 0.05	4.307ThrVal: 4.307 ± 0.065	0.751ThrTrp: 0.751 ± 0.029	1.233ThrTyr: 1.233 ± 0.037	0.0ThrXaa: 0.0 ± 0.0
Val	9.45ValAla: 9.45 ± 0.104	0.611ValCys: 0.611 ± 0.022	4.15ValAsp: 4.15 ± 0.072	5.151ValGlu: 5.151 ± 0.072	2.849ValPhe: 2.849 ± 0.063	5.72ValGly: 5.72 ± 0.08	1.398ValHis: 1.398 ± 0.035	4.072ValIle: 4.072 ± 0.069	1.81ValLys: 1.81 ± 0.044	7.546ValLeu: 7.546 ± 0.099	1.967ValMet: 1.967 ± 0.035	1.858ValAsn: 1.858 ± 0.042	3.85ValPro: 3.85 ± 0.063	1.997ValGln: 1.997 ± 0.045	4.752ValArg: 4.752 ± 0.066	4.222ValSer: 4.222 ± 0.066	4.813ValThr: 4.813 ± 0.063	5.963ValVal: 5.963 ± 0.081	0.961ValTrp: 0.961 ± 0.03	1.433ValTyr: 1.433 ± 0.035	0.0ValXaa: 0.0 ± 0.0
Trp	1.366TrpAla: 1.366 ± 0.037	0.144TrpCys: 0.144 ± 0.011	0.755TrpAsp: 0.755 ± 0.027	0.64TrpGlu: 0.64 ± 0.025	0.536TrpPhe: 0.536 ± 0.023	0.978TrpGly: 0.978 ± 0.032	0.339TrpHis: 0.339 ± 0.019	0.731TrpIle: 0.731 ± 0.03	0.387TrpLys: 0.387 ± 0.018	1.612TrpLeu: 1.612 ± 0.041	0.389TrpMet: 0.389 ± 0.019	0.424TrpAsn: 0.424 ± 0.02	0.767TrpPro: 0.767 ± 0.027	0.598TrpGln: 0.598 ± 0.022	1.232TrpArg: 1.232 ± 0.037	0.85TrpSer: 0.85 ± 0.031	0.838TrpThr: 0.838 ± 0.03	0.916TrpVal: 0.916 ± 0.032	0.239TrpTrp: 0.239 ± 0.016	0.272TrpTyr: 0.272 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.443TyrAla: 2.443 ± 0.042	0.221TyrCys: 0.221 ± 0.014	1.601TyrAsp: 1.601 ± 0.04	1.288TyrGlu: 1.288 ± 0.033	0.823TyrPhe: 0.823 ± 0.028	2.046TyrGly: 2.046 ± 0.043	0.499TyrHis: 0.499 ± 0.02	0.822TyrIle: 0.822 ± 0.032	0.442TyrLys: 0.442 ± 0.021	2.185TyrLeu: 2.185 ± 0.042	0.431TyrMet: 0.431 ± 0.02	0.516TyrAsn: 0.516 ± 0.022	1.049TyrPro: 1.049 ± 0.032	0.628TyrGln: 0.628 ± 0.025	1.563TyrArg: 1.563 ± 0.036	1.082TyrSer: 1.082 ± 0.033	1.035TyrThr: 1.035 ± 0.029	1.487TyrVal: 1.487 ± 0.036	0.336TyrTrp: 0.336 ± 0.02	0.524TyrTyr: 0.524 ± 0.022	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3664 proteins (1119639 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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