Amino acid dipepetide frequency for Swinepox virus (strain Swine/Nebraska/17077-99/1999) (SWPV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.232AlaAla: 1.232 ± 0.196
0.605AlaCys: 0.605 ± 0.103
1.427AlaAsp: 1.427 ± 0.189
0.821AlaGlu: 0.821 ± 0.141
1.189AlaPhe: 1.189 ± 0.188
0.865AlaGly: 0.865 ± 0.159
0.389AlaHis: 0.389 ± 0.106
3.264AlaIle: 3.264 ± 0.251
1.707AlaLys: 1.707 ± 0.204
2.205AlaLeu: 2.205 ± 0.188
0.692AlaMet: 0.692 ± 0.121
1.491AlaAsn: 1.491 ± 0.158
0.519AlaPro: 0.519 ± 0.103
0.303AlaGln: 0.303 ± 0.085
1.405AlaArg: 1.405 ± 0.211
2.529AlaSer: 2.529 ± 0.312
1.621AlaThr: 1.621 ± 0.19
1.837AlaVal: 1.837 ± 0.231
0.173AlaTrp: 0.173 ± 0.053
1.383AlaTyr: 1.383 ± 0.172
0.0AlaXaa: 0.0 ± 0.0
Cys
0.519CysAla: 0.519 ± 0.12
0.648CysCys: 0.648 ± 0.126
1.34CysAsp: 1.34 ± 0.162
1.059CysGlu: 1.059 ± 0.146
0.648CysPhe: 0.648 ± 0.095
0.994CysGly: 0.994 ± 0.147
0.259CysHis: 0.259 ± 0.072
2.983CysIle: 2.983 ± 0.29
1.599CysLys: 1.599 ± 0.194
1.707CysLeu: 1.707 ± 0.224
0.562CysMet: 0.562 ± 0.105
1.621CysAsn: 1.621 ± 0.196
0.67CysPro: 0.67 ± 0.149
0.281CysGln: 0.281 ± 0.084
0.562CysArg: 0.562 ± 0.123
2.032CysSer: 2.032 ± 0.218
0.929CysThr: 0.929 ± 0.166
1.232CysVal: 1.232 ± 0.163
0.216CysTrp: 0.216 ± 0.058
1.427CysTyr: 1.427 ± 0.17
0.0CysXaa: 0.0 ± 0.0
Asp
1.664AspAla: 1.664 ± 0.178
1.016AspCys: 1.016 ± 0.171
5.036AspAsp: 5.036 ± 0.384
3.437AspGlu: 3.437 ± 0.313
3.285AspPhe: 3.285 ± 0.25
2.053AspGly: 2.053 ± 0.21
0.8AspHis: 0.8 ± 0.137
10.461AspIle: 10.461 ± 0.52
5.079AspLys: 5.079 ± 0.388
4.236AspLeu: 4.236 ± 0.279
1.794AspMet: 1.794 ± 0.187
5.468AspAsn: 5.468 ± 0.399
1.578AspPro: 1.578 ± 0.18
1.059AspGln: 1.059 ± 0.169
1.794AspArg: 1.794 ± 0.19
3.869AspSer: 3.869 ± 0.258
4.301AspThr: 4.301 ± 0.297
4.085AspVal: 4.085 ± 0.289
0.411AspTrp: 0.411 ± 0.099
3.48AspTyr: 3.48 ± 0.253
0.0AspXaa: 0.0 ± 0.0
Glu
1.297GluAla: 1.297 ± 0.162
0.8GluCys: 0.8 ± 0.148
3.372GluAsp: 3.372 ± 0.28
3.177GluGlu: 3.177 ± 0.282
2.356GluPhe: 2.356 ± 0.213
1.189GluGly: 1.189 ± 0.186
1.081GluHis: 1.081 ± 0.126
4.712GluIle: 4.712 ± 0.299
4.301GluLys: 4.301 ± 0.31
5.447GluLeu: 5.447 ± 0.395
1.167GluMet: 1.167 ± 0.136
3.545GluAsn: 3.545 ± 0.354
1.34GluPro: 1.34 ± 0.203
1.102GluGln: 1.102 ± 0.161
1.837GluArg: 1.837 ± 0.229
3.48GluSer: 3.48 ± 0.263
2.961GluThr: 2.961 ± 0.285
2.161GluVal: 2.161 ± 0.192
0.346GluTrp: 0.346 ± 0.09
3.653GluTyr: 3.653 ± 0.228
0.0GluXaa: 0.0 ± 0.0
Phe
1.146PheAla: 1.146 ± 0.181
0.908PheCys: 0.908 ± 0.164
3.242PheAsp: 3.242 ± 0.334
1.988PheGlu: 1.988 ± 0.165
2.615PhePhe: 2.615 ± 0.228
2.053PheGly: 2.053 ± 0.191
0.843PheHis: 0.843 ± 0.119
6.808PheIle: 6.808 ± 0.359
3.22PheLys: 3.22 ± 0.239
4.474PheLeu: 4.474 ± 0.367
1.34PheMet: 1.34 ± 0.168
3.934PheAsn: 3.934 ± 0.292
1.47PhePro: 1.47 ± 0.175
0.821PheGln: 0.821 ± 0.139
1.599PheArg: 1.599 ± 0.19
4.301PheSer: 4.301 ± 0.268
3.026PheThr: 3.026 ± 0.272
2.68PheVal: 2.68 ± 0.244
0.411PheTrp: 0.411 ± 0.114
2.313PheTyr: 2.313 ± 0.181
0.0PheXaa: 0.0 ± 0.0
Gly
1.081GlyAla: 1.081 ± 0.194
0.692GlyCys: 0.692 ± 0.115
2.161GlyAsp: 2.161 ± 0.25
1.729GlyGlu: 1.729 ± 0.181
2.118GlyPhe: 2.118 ± 0.213
1.794GlyGly: 1.794 ± 0.289
0.54GlyHis: 0.54 ± 0.118
4.733GlyIle: 4.733 ± 0.313
3.177GlyLys: 3.177 ± 0.295
2.075GlyLeu: 2.075 ± 0.231
0.67GlyMet: 0.67 ± 0.118
2.875GlyAsn: 2.875 ± 0.258
0.67GlyPro: 0.67 ± 0.095
0.562GlyGln: 0.562 ± 0.108
1.405GlyArg: 1.405 ± 0.19
2.637GlySer: 2.637 ± 0.225
1.729GlyThr: 1.729 ± 0.221
1.88GlyVal: 1.88 ± 0.192
0.303GlyTrp: 0.303 ± 0.068
2.529GlyTyr: 2.529 ± 0.274
0.0GlyXaa: 0.0 ± 0.0
His
0.519HisAla: 0.519 ± 0.112
0.605HisCys: 0.605 ± 0.13
1.47HisAsp: 1.47 ± 0.174
0.843HisGlu: 0.843 ± 0.121
0.951HisPhe: 0.951 ± 0.15
1.124HisGly: 1.124 ± 0.155
0.411HisHis: 0.411 ± 0.11
2.723HisIle: 2.723 ± 0.23
1.47HisLys: 1.47 ± 0.159
1.794HisLeu: 1.794 ± 0.239
0.821HisMet: 0.821 ± 0.146
1.535HisAsn: 1.535 ± 0.196
0.648HisPro: 0.648 ± 0.11
0.324HisGln: 0.324 ± 0.074
1.016HisArg: 1.016 ± 0.124
1.124HisSer: 1.124 ± 0.137
1.124HisThr: 1.124 ± 0.141
1.232HisVal: 1.232 ± 0.205
0.195HisTrp: 0.195 ± 0.065
0.584HisTyr: 0.584 ± 0.126
0.0HisXaa: 0.0 ± 0.0
Ile
3.199IleAla: 3.199 ± 0.29
2.81IleCys: 2.81 ± 0.289
8.732IleAsp: 8.732 ± 0.469
5.879IleGlu: 5.879 ± 0.385
5.684IlePhe: 5.684 ± 0.379
3.847IleGly: 3.847 ± 0.29
2.788IleHis: 2.788 ± 0.218
13.098IleIle: 13.098 ± 0.729
10.245IleLys: 10.245 ± 0.519
11.066IleLeu: 11.066 ± 0.584
2.442IleMet: 2.442 ± 0.27
9.877IleAsn: 9.877 ± 0.472
3.285IlePro: 3.285 ± 0.335
2.767IleGln: 2.767 ± 0.193
4.539IleArg: 4.539 ± 0.345
9.748IleSer: 9.748 ± 0.455
7.241IleThr: 7.241 ± 0.442
5.944IleVal: 5.944 ± 0.397
0.584IleTrp: 0.584 ± 0.098
6.722IleTyr: 6.722 ± 0.406
0.0IleXaa: 0.0 ± 0.0
Lys
1.729LysAla: 1.729 ± 0.221
1.513LysCys: 1.513 ± 0.194
5.079LysAsp: 5.079 ± 0.421
4.042LysGlu: 4.042 ± 0.291
3.199LysPhe: 3.199 ± 0.264
2.356LysGly: 2.356 ± 0.23
2.334LysHis: 2.334 ± 0.202
9.186LysIle: 9.186 ± 0.515
8.127LysLys: 8.127 ± 0.464
7.197LysLeu: 7.197 ± 0.349
2.032LysMet: 2.032 ± 0.209
6.527LysAsn: 6.527 ± 0.39
2.032LysPro: 2.032 ± 0.199
2.486LysGln: 2.486 ± 0.216
3.329LysArg: 3.329 ± 0.247
6.246LysSer: 6.246 ± 0.403
4.236LysThr: 4.236 ± 0.361
3.631LysVal: 3.631 ± 0.237
0.67LysTrp: 0.67 ± 0.133
5.749LysTyr: 5.749 ± 0.442
0.0LysXaa: 0.0 ± 0.0
Leu
2.637LeuAla: 2.637 ± 0.242
1.945LeuCys: 1.945 ± 0.199
4.928LeuAsp: 4.928 ± 0.319
4.841LeuGlu: 4.841 ± 0.34
5.166LeuPhe: 5.166 ± 0.43
3.156LeuGly: 3.156 ± 0.316
1.599LeuHis: 1.599 ± 0.18
8.105LeuIle: 8.105 ± 0.502
6.527LeuLys: 6.527 ± 0.445
8.537LeuLeu: 8.537 ± 0.545
2.226LeuMet: 2.226 ± 0.29
5.965LeuAsn: 5.965 ± 0.465
2.788LeuPro: 2.788 ± 0.217
2.14LeuGln: 2.14 ± 0.202
3.501LeuArg: 3.501 ± 0.249
8.408LeuSer: 8.408 ± 0.393
4.733LeuThr: 4.733 ± 0.323
4.085LeuVal: 4.085 ± 0.278
0.497LeuTrp: 0.497 ± 0.129
4.885LeuTyr: 4.885 ± 0.33
0.0LeuXaa: 0.0 ± 0.0
Met
0.648MetAla: 0.648 ± 0.11
0.519MetCys: 0.519 ± 0.106
1.772MetAsp: 1.772 ± 0.182
1.427MetGlu: 1.427 ± 0.192
1.556MetPhe: 1.556 ± 0.178
0.778MetGly: 0.778 ± 0.11
0.605MetHis: 0.605 ± 0.123
2.529MetIle: 2.529 ± 0.257
1.816MetLys: 1.816 ± 0.206
2.032MetLeu: 2.032 ± 0.22
0.562MetMet: 0.562 ± 0.138
2.032MetAsn: 2.032 ± 0.219
0.627MetPro: 0.627 ± 0.117
0.389MetGln: 0.389 ± 0.094
1.081MetArg: 1.081 ± 0.169
2.464MetSer: 2.464 ± 0.286
1.275MetThr: 1.275 ± 0.165
1.146MetVal: 1.146 ± 0.164
0.216MetTrp: 0.216 ± 0.068
1.686MetTyr: 1.686 ± 0.179
0.0MetXaa: 0.0 ± 0.0
Asn
1.599AsnAla: 1.599 ± 0.199
1.275AsnCys: 1.275 ± 0.174
5.425AsnAsp: 5.425 ± 0.406
4.366AsnGlu: 4.366 ± 0.297
2.875AsnPhe: 2.875 ± 0.231
3.069AsnGly: 3.069 ± 0.295
1.794AsnHis: 1.794 ± 0.205
11.542AsnIle: 11.542 ± 0.513
6.592AsnLys: 6.592 ± 0.352
4.452AsnLeu: 4.452 ± 0.392
2.205AsnMet: 2.205 ± 0.225
8.537AsnAsn: 8.537 ± 0.5
2.55AsnPro: 2.55 ± 0.243
1.427AsnGln: 1.427 ± 0.166
2.723AsnArg: 2.723 ± 0.252
4.69AsnSer: 4.69 ± 0.352
5.187AsnThr: 5.187 ± 0.417
3.977AsnVal: 3.977 ± 0.354
0.454AsnTrp: 0.454 ± 0.112
4.107AsnTyr: 4.107 ± 0.258
0.0AsnXaa: 0.0 ± 0.0
Pro
0.497ProAla: 0.497 ± 0.11
0.519ProCys: 0.519 ± 0.094
1.794ProAsp: 1.794 ± 0.198
1.448ProGlu: 1.448 ± 0.226
1.686ProPhe: 1.686 ± 0.224
1.059ProGly: 1.059 ± 0.163
0.519ProHis: 0.519 ± 0.113
3.177ProIle: 3.177 ± 0.251
2.118ProLys: 2.118 ± 0.266
2.961ProLeu: 2.961 ± 0.26
0.67ProMet: 0.67 ± 0.147
1.988ProAsn: 1.988 ± 0.175
0.908ProPro: 0.908 ± 0.188
0.476ProGln: 0.476 ± 0.109
1.102ProArg: 1.102 ± 0.146
2.248ProSer: 2.248 ± 0.23
1.902ProThr: 1.902 ± 0.229
1.556ProVal: 1.556 ± 0.166
0.281ProTrp: 0.281 ± 0.068
1.664ProTyr: 1.664 ± 0.199
0.0ProXaa: 0.0 ± 0.0
Gln
0.238GlnAla: 0.238 ± 0.083
0.411GlnCys: 0.411 ± 0.084
1.167GlnAsp: 1.167 ± 0.155
1.016GlnGlu: 1.016 ± 0.154
0.692GlnPhe: 0.692 ± 0.124
0.67GlnGly: 0.67 ± 0.113
0.627GlnHis: 0.627 ± 0.13
1.859GlnIle: 1.859 ± 0.195
1.707GlnLys: 1.707 ± 0.232
2.399GlnLeu: 2.399 ± 0.25
0.562GlnMet: 0.562 ± 0.103
1.081GlnAsn: 1.081 ± 0.186
0.778GlnPro: 0.778 ± 0.146
0.67GlnGln: 0.67 ± 0.117
0.994GlnArg: 0.994 ± 0.161
1.751GlnSer: 1.751 ± 0.186
1.254GlnThr: 1.254 ± 0.213
0.973GlnVal: 0.973 ± 0.147
0.303GlnTrp: 0.303 ± 0.083
1.383GlnTyr: 1.383 ± 0.183
0.0GlnXaa: 0.0 ± 0.0
Arg
0.951ArgAla: 0.951 ± 0.109
0.929ArgCys: 0.929 ± 0.148
2.313ArgAsp: 2.313 ± 0.221
1.772ArgGlu: 1.772 ± 0.227
1.988ArgPhe: 1.988 ± 0.238
1.448ArgGly: 1.448 ± 0.2
0.821ArgHis: 0.821 ± 0.114
4.258ArgIle: 4.258 ± 0.331
3.156ArgLys: 3.156 ± 0.301
3.35ArgLeu: 3.35 ± 0.271
0.843ArgMet: 0.843 ± 0.122
2.745ArgAsn: 2.745 ± 0.193
0.843ArgPro: 0.843 ± 0.165
1.081ArgGln: 1.081 ± 0.176
1.772ArgArg: 1.772 ± 0.174
2.788ArgSer: 2.788 ± 0.255
1.794ArgThr: 1.794 ± 0.186
2.075ArgVal: 2.075 ± 0.247
0.151ArgTrp: 0.151 ± 0.063
2.68ArgTyr: 2.68 ± 0.236
0.0ArgXaa: 0.0 ± 0.0
Ser
2.01SerAla: 2.01 ± 0.227
1.88SerCys: 1.88 ± 0.191
4.993SerAsp: 4.993 ± 0.342
3.415SerGlu: 3.415 ± 0.303
3.653SerPhe: 3.653 ± 0.293
2.572SerGly: 2.572 ± 0.218
1.405SerHis: 1.405 ± 0.21
10.007SerIle: 10.007 ± 0.435
6.743SerLys: 6.743 ± 0.368
7.284SerLeu: 7.284 ± 0.413
2.118SerMet: 2.118 ± 0.165
6.117SerAsn: 6.117 ± 0.408
2.269SerPro: 2.269 ± 0.263
1.988SerGln: 1.988 ± 0.243
2.767SerArg: 2.767 ± 0.304
7.003SerSer: 7.003 ± 0.411
4.604SerThr: 4.604 ± 0.35
4.409SerVal: 4.409 ± 0.31
0.367SerTrp: 0.367 ± 0.099
4.02SerTyr: 4.02 ± 0.307
0.0SerXaa: 0.0 ± 0.0
Thr
1.491ThrAla: 1.491 ± 0.21
1.405ThrCys: 1.405 ± 0.232
3.739ThrAsp: 3.739 ± 0.254
2.658ThrGlu: 2.658 ± 0.294
3.156ThrPhe: 3.156 ± 0.251
1.816ThrGly: 1.816 ± 0.15
1.232ThrHis: 1.232 ± 0.147
6.938ThrIle: 6.938 ± 0.446
4.366ThrLys: 4.366 ± 0.241
5.209ThrLeu: 5.209 ± 0.304
1.621ThrMet: 1.621 ± 0.204
4.258ThrAsn: 4.258 ± 0.327
2.01ThrPro: 2.01 ± 0.236
0.8ThrGln: 0.8 ± 0.13
1.945ThrArg: 1.945 ± 0.193
4.582ThrSer: 4.582 ± 0.37
3.48ThrThr: 3.48 ± 0.354
3.156ThrVal: 3.156 ± 0.234
0.432ThrTrp: 0.432 ± 0.092
3.329ThrTyr: 3.329 ± 0.263
0.0ThrXaa: 0.0 ± 0.0
Val
1.751ValAla: 1.751 ± 0.202
1.34ValCys: 1.34 ± 0.175
3.112ValAsp: 3.112 ± 0.265
2.464ValGlu: 2.464 ± 0.216
3.004ValPhe: 3.004 ± 0.275
1.837ValGly: 1.837 ± 0.195
1.275ValHis: 1.275 ± 0.168
5.382ValIle: 5.382 ± 0.36
4.301ValLys: 4.301 ± 0.323
4.798ValLeu: 4.798 ± 0.315
1.254ValMet: 1.254 ± 0.151
3.977ValAsn: 3.977 ± 0.308
1.535ValPro: 1.535 ± 0.19
0.756ValGln: 0.756 ± 0.142
1.837ValArg: 1.837 ± 0.179
4.755ValSer: 4.755 ± 0.293
2.615ValThr: 2.615 ± 0.299
2.442ValVal: 2.442 ± 0.223
0.303ValTrp: 0.303 ± 0.073
3.35ValTyr: 3.35 ± 0.294
0.0ValXaa: 0.0 ± 0.0
Trp
0.13TrpAla: 0.13 ± 0.05
0.108TrpCys: 0.108 ± 0.049
0.259TrpAsp: 0.259 ± 0.076
0.367TrpGlu: 0.367 ± 0.084
0.497TrpPhe: 0.497 ± 0.105
0.324TrpGly: 0.324 ± 0.086
0.043TrpHis: 0.043 ± 0.035
0.951TrpIle: 0.951 ± 0.15
0.756TrpLys: 0.756 ± 0.141
0.605TrpLeu: 0.605 ± 0.104
0.259TrpMet: 0.259 ± 0.077
0.432TrpAsn: 0.432 ± 0.098
0.173TrpPro: 0.173 ± 0.057
0.043TrpGln: 0.043 ± 0.033
0.303TrpArg: 0.303 ± 0.078
0.519TrpSer: 0.519 ± 0.115
0.303TrpThr: 0.303 ± 0.076
0.259TrpVal: 0.259 ± 0.065
0.022TrpTrp: 0.022 ± 0.021
0.411TrpTyr: 0.411 ± 0.107
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.318TyrAla: 1.318 ± 0.202
1.362TyrCys: 1.362 ± 0.187
3.545TyrAsp: 3.545 ± 0.306
2.572TyrGlu: 2.572 ± 0.236
2.875TyrPhe: 2.875 ± 0.207
2.356TyrGly: 2.356 ± 0.238
1.146TyrHis: 1.146 ± 0.15
7.803TyrIle: 7.803 ± 0.479
4.69TyrLys: 4.69 ± 0.329
4.841TyrLeu: 4.841 ± 0.323
1.297TyrMet: 1.297 ± 0.155
4.841TyrAsn: 4.841 ± 0.37
1.88TyrPro: 1.88 ± 0.208
1.059TyrGln: 1.059 ± 0.182
2.248TyrArg: 2.248 ± 0.247
4.452TyrSer: 4.452 ± 0.265
3.307TyrThr: 3.307 ± 0.256
3.329TyrVal: 3.329 ± 0.268
0.432TyrTrp: 0.432 ± 0.108
2.572TyrTyr: 2.572 ± 0.273
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 146 proteins (46268 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski