Amino acid dipepetide frequency for Rice latent virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.984AlaAla: 1.984 ± 1.953
0.0AlaCys: 0.0 ± 0.0
2.976AlaAsp: 2.976 ± 1.459
4.96AlaGlu: 4.96 ± 2.266
0.992AlaPhe: 0.992 ± 0.976
1.984AlaGly: 1.984 ± 1.74
0.0AlaHis: 0.0 ± 0.0
2.976AlaIle: 2.976 ± 2.929
1.984AlaLys: 1.984 ± 0.858
2.976AlaLeu: 2.976 ± 2.346
0.992AlaMet: 0.992 ± 0.966
0.992AlaAsn: 0.992 ± 1.567
5.952AlaPro: 5.952 ± 1.982
5.952AlaGln: 5.952 ± 2.78
6.944AlaArg: 6.944 ± 4.307
4.96AlaSer: 4.96 ± 1.248
6.944AlaThr: 6.944 ± 1.659
1.984AlaVal: 1.984 ± 1.74
0.0AlaTrp: 0.0 ± 0.0
0.992AlaTyr: 0.992 ± 1.567
0.0AlaXaa: 0.0 ± 0.0
Cys
0.992CysAla: 0.992 ± 0.976
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.984CysGlu: 1.984 ± 0.858
0.0CysPhe: 0.0 ± 0.0
1.984CysGly: 1.984 ± 0.864
0.992CysHis: 0.992 ± 0.725
0.0CysIle: 0.0 ± 0.0
1.984CysLys: 1.984 ± 0.858
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
2.976CysPro: 2.976 ± 1.39
1.984CysGln: 1.984 ± 0.858
0.0CysArg: 0.0 ± 0.0
2.976CysSer: 2.976 ± 0.477
1.984CysThr: 1.984 ± 0.864
1.984CysVal: 1.984 ± 1.508
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.96AspAla: 4.96 ± 2.741
0.0AspCys: 0.0 ± 0.0
1.984AspAsp: 1.984 ± 0.864
0.992AspGlu: 0.992 ± 0.725
1.984AspPhe: 1.984 ± 0.864
2.976AspGly: 2.976 ± 0.477
0.0AspHis: 0.0 ± 0.0
3.968AspIle: 3.968 ± 1.275
0.992AspLys: 0.992 ± 0.976
1.984AspLeu: 1.984 ± 1.668
0.0AspMet: 0.0 ± 0.0
0.992AspAsn: 0.992 ± 0.976
5.952AspPro: 5.952 ± 1.452
3.968AspGln: 3.968 ± 0.943
0.0AspArg: 0.0 ± 0.0
3.968AspSer: 3.968 ± 1.646
4.96AspThr: 4.96 ± 0.986
0.992AspVal: 0.992 ± 0.769
3.968AspTrp: 3.968 ± 1.716
5.952AspTyr: 5.952 ± 2.574
0.0AspXaa: 0.0 ± 0.0
Glu
1.984GluAla: 1.984 ± 0.902
0.0GluCys: 0.0 ± 0.0
3.968GluAsp: 3.968 ± 2.044
3.968GluGlu: 3.968 ± 1.154
1.984GluPhe: 1.984 ± 0.858
3.968GluGly: 3.968 ± 1.964
0.0GluHis: 0.0 ± 0.0
0.992GluIle: 0.992 ± 1.567
1.984GluLys: 1.984 ± 0.858
1.984GluLeu: 1.984 ± 0.858
0.0GluMet: 0.0 ± 0.0
2.976GluAsn: 2.976 ± 0.477
0.992GluPro: 0.992 ± 0.976
2.976GluGln: 2.976 ± 1.459
0.992GluArg: 0.992 ± 0.769
2.976GluSer: 2.976 ± 1.39
1.984GluThr: 1.984 ± 0.858
0.992GluVal: 0.992 ± 0.769
2.976GluTrp: 2.976 ± 0.477
4.96GluTyr: 4.96 ± 2.266
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.0PheCys: 0.0 ± 0.0
3.968PheAsp: 3.968 ± 1.716
3.968PheGlu: 3.968 ± 1.154
5.952PhePhe: 5.952 ± 1.452
1.984PheGly: 1.984 ± 1.74
1.984PheHis: 1.984 ± 0.858
0.0PheIle: 0.0 ± 0.0
3.968PheLys: 3.968 ± 1.5
2.976PheLeu: 2.976 ± 1.49
0.0PheMet: 0.0 ± 0.0
0.0PheAsn: 0.0 ± 0.0
3.968PhePro: 3.968 ± 1.716
0.992PheGln: 0.992 ± 0.976
2.976PheArg: 2.976 ± 2.929
5.952PheSer: 5.952 ± 1.052
1.984PheThr: 1.984 ± 0.864
1.984PheVal: 1.984 ± 1.74
0.992PheTrp: 0.992 ± 0.976
2.976PheTyr: 2.976 ± 1.49
0.0PheXaa: 0.0 ± 0.0
Gly
2.976GlyAla: 2.976 ± 1.453
0.992GlyCys: 0.992 ± 0.725
3.968GlyAsp: 3.968 ± 2.628
2.976GlyGlu: 2.976 ± 0.477
2.976GlyPhe: 2.976 ± 3.164
3.968GlyGly: 3.968 ± 2.628
0.0GlyHis: 0.0 ± 0.0
1.984GlyIle: 1.984 ± 0.864
3.968GlyLys: 3.968 ± 1.867
1.984GlyLeu: 1.984 ± 0.864
0.0GlyMet: 0.0 ± 0.0
3.968GlyAsn: 3.968 ± 3.145
1.984GlyPro: 1.984 ± 0.864
2.976GlyGln: 2.976 ± 1.716
0.992GlyArg: 0.992 ± 0.976
11.905GlySer: 11.905 ± 3.937
3.968GlyThr: 3.968 ± 0.943
4.96GlyVal: 4.96 ± 4.014
1.984GlyTrp: 1.984 ± 1.74
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.992HisAsp: 0.992 ± 0.769
0.0HisGlu: 0.0 ± 0.0
0.992HisPhe: 0.992 ± 0.976
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
2.976HisLys: 2.976 ± 0.477
1.984HisLeu: 1.984 ± 0.858
0.0HisMet: 0.0 ± 0.0
1.984HisAsn: 1.984 ± 0.858
2.976HisPro: 2.976 ± 1.39
1.984HisGln: 1.984 ± 0.858
1.984HisArg: 1.984 ± 0.864
1.984HisSer: 1.984 ± 0.858
2.976HisThr: 2.976 ± 0.477
0.992HisVal: 0.992 ± 0.769
0.0HisTrp: 0.0 ± 0.0
2.976HisTyr: 2.976 ± 1.39
0.0HisXaa: 0.0 ± 0.0
Ile
2.976IleAla: 2.976 ± 0.477
0.0IleCys: 0.0 ± 0.0
1.984IleAsp: 1.984 ± 0.864
0.992IleGlu: 0.992 ± 0.725
0.992IlePhe: 0.992 ± 0.976
4.96IleGly: 4.96 ± 2.71
0.992IleHis: 0.992 ± 0.725
3.968IleIle: 3.968 ± 0.831
2.976IleLys: 2.976 ± 0.477
4.96IleLeu: 4.96 ± 1.043
0.0IleMet: 0.0 ± 0.0
1.984IleAsn: 1.984 ± 1.953
2.976IlePro: 2.976 ± 1.39
0.0IleGln: 0.0 ± 0.0
0.992IleArg: 0.992 ± 0.976
2.976IleSer: 2.976 ± 1.39
1.984IleThr: 1.984 ± 0.858
0.992IleVal: 0.992 ± 0.976
0.992IleTrp: 0.992 ± 0.976
3.968IleTyr: 3.968 ± 1.275
0.0IleXaa: 0.0 ± 0.0
Lys
0.992LysAla: 0.992 ± 1.567
2.976LysCys: 2.976 ± 0.477
7.937LysAsp: 7.937 ± 1.534
0.0LysGlu: 0.0 ± 0.0
1.984LysPhe: 1.984 ± 1.953
2.976LysGly: 2.976 ± 2.929
1.984LysHis: 1.984 ± 1.45
1.984LysIle: 1.984 ± 0.858
2.976LysLys: 2.976 ± 0.477
2.976LysLeu: 2.976 ± 0.477
2.976LysMet: 2.976 ± 0.477
0.992LysAsn: 0.992 ± 0.976
4.96LysPro: 4.96 ± 0.986
2.976LysGln: 2.976 ± 1.39
5.952LysArg: 5.952 ± 1.982
0.992LysSer: 0.992 ± 0.976
7.937LysThr: 7.937 ± 2.235
0.992LysVal: 0.992 ± 0.725
0.992LysTrp: 0.992 ± 0.976
4.96LysTyr: 4.96 ± 2.734
0.0LysXaa: 0.0 ± 0.0
Leu
1.984LeuAla: 1.984 ± 0.858
1.984LeuCys: 1.984 ± 1.74
1.984LeuAsp: 1.984 ± 0.902
1.984LeuGlu: 1.984 ± 0.858
4.96LeuPhe: 4.96 ± 2.71
4.96LeuGly: 4.96 ± 2.741
5.952LeuHis: 5.952 ± 2.574
0.992LeuIle: 0.992 ± 0.725
1.984LeuLys: 1.984 ± 0.858
8.929LeuLeu: 8.929 ± 3.217
2.976LeuMet: 2.976 ± 1.311
0.0LeuAsn: 0.0 ± 0.0
0.992LeuPro: 0.992 ± 0.976
4.96LeuGln: 4.96 ± 1.653
2.976LeuArg: 2.976 ± 0.477
6.944LeuSer: 6.944 ± 3.027
9.921LeuThr: 9.921 ± 3.852
6.944LeuVal: 6.944 ± 2.548
0.0LeuTrp: 0.0 ± 0.0
1.984LeuTyr: 1.984 ± 0.864
0.0LeuXaa: 0.0 ± 0.0
Met
2.976MetAla: 2.976 ± 1.49
0.992MetCys: 0.992 ± 0.976
0.992MetAsp: 0.992 ± 0.769
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
2.976MetLeu: 2.976 ± 1.363
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.992MetPro: 0.992 ± 0.976
0.0MetGln: 0.0 ± 0.0
2.976MetArg: 2.976 ± 0.477
0.0MetSer: 0.0 ± 0.0
1.984MetThr: 1.984 ± 0.902
1.984MetVal: 1.984 ± 0.858
0.992MetTrp: 0.992 ± 0.976
1.984MetTyr: 1.984 ± 0.858
0.0MetXaa: 0.0 ± 0.0
Asn
1.984AsnAla: 1.984 ± 0.858
4.96AsnCys: 4.96 ± 2.193
0.992AsnAsp: 0.992 ± 0.976
0.992AsnGlu: 0.992 ± 0.725
0.992AsnPhe: 0.992 ± 1.567
3.968AsnGly: 3.968 ± 2.628
0.0AsnHis: 0.0 ± 0.0
1.984AsnIle: 1.984 ± 0.858
0.0AsnLys: 0.0 ± 0.0
0.992AsnLeu: 0.992 ± 0.976
0.992AsnMet: 0.992 ± 0.769
0.0AsnAsn: 0.0 ± 0.0
1.984AsnPro: 1.984 ± 0.864
0.992AsnGln: 0.992 ± 0.976
3.968AsnArg: 3.968 ± 1.275
0.992AsnSer: 0.992 ± 0.976
2.976AsnThr: 2.976 ± 1.62
1.984AsnVal: 1.984 ± 0.864
0.992AsnTrp: 0.992 ± 0.725
0.992AsnTyr: 0.992 ± 0.725
0.0AsnXaa: 0.0 ± 0.0
Pro
4.96ProAla: 4.96 ± 1.043
0.0ProCys: 0.0 ± 0.0
0.992ProAsp: 0.992 ± 0.976
3.968ProGlu: 3.968 ± 1.805
4.96ProPhe: 4.96 ± 2.193
5.952ProGly: 5.952 ± 1.561
0.992ProHis: 0.992 ± 0.769
1.984ProIle: 1.984 ± 0.858
4.96ProLys: 4.96 ± 1.165
2.976ProLeu: 2.976 ± 1.716
0.0ProMet: 0.0 ± 0.0
2.976ProAsn: 2.976 ± 1.39
3.968ProPro: 3.968 ± 2.643
0.0ProGln: 0.0 ± 0.0
0.0ProArg: 0.0 ± 0.0
5.952ProSer: 5.952 ± 3.038
8.929ProThr: 8.929 ± 2.354
1.984ProVal: 1.984 ± 0.858
1.984ProTrp: 1.984 ± 0.858
3.968ProTyr: 3.968 ± 0.943
0.0ProXaa: 0.0 ± 0.0
Gln
1.984GlnAla: 1.984 ± 1.74
0.992GlnCys: 0.992 ± 0.725
0.0GlnAsp: 0.0 ± 0.0
1.984GlnGlu: 1.984 ± 1.537
4.96GlnPhe: 4.96 ± 0.986
0.992GlnGly: 0.992 ± 0.976
0.992GlnHis: 0.992 ± 0.769
0.0GlnIle: 0.0 ± 0.0
0.992GlnLys: 0.992 ± 0.976
6.944GlnLeu: 6.944 ± 3.027
1.984GlnMet: 1.984 ± 1.726
2.976GlnAsn: 2.976 ± 1.459
4.96GlnPro: 4.96 ± 2.908
0.992GlnGln: 0.992 ± 0.769
1.984GlnArg: 1.984 ± 1.74
3.968GlnSer: 3.968 ± 1.275
3.968GlnThr: 3.968 ± 1.716
2.976GlnVal: 2.976 ± 0.477
1.984GlnTrp: 1.984 ± 0.858
0.992GlnTyr: 0.992 ± 0.725
0.0GlnXaa: 0.0 ± 0.0
Arg
4.96ArgAla: 4.96 ± 2.22
1.984ArgCys: 1.984 ± 0.858
4.96ArgAsp: 4.96 ± 1.165
1.984ArgGlu: 1.984 ± 0.858
2.976ArgPhe: 2.976 ± 0.477
1.984ArgGly: 1.984 ± 1.74
0.992ArgHis: 0.992 ± 0.976
1.984ArgIle: 1.984 ± 1.953
4.96ArgLys: 4.96 ± 1.165
4.96ArgLeu: 4.96 ± 0.986
0.992ArgMet: 0.992 ± 0.769
0.0ArgAsn: 0.0 ± 0.0
0.992ArgPro: 0.992 ± 0.976
4.96ArgGln: 4.96 ± 2.379
7.937ArgArg: 7.937 ± 2.847
1.984ArgSer: 1.984 ± 0.864
5.952ArgThr: 5.952 ± 1.171
3.968ArgVal: 3.968 ± 1.154
0.992ArgTrp: 0.992 ± 0.976
0.992ArgTyr: 0.992 ± 0.725
0.0ArgXaa: 0.0 ± 0.0
Ser
8.929SerAla: 8.929 ± 4.618
0.0SerCys: 0.0 ± 0.0
1.984SerAsp: 1.984 ± 0.858
1.984SerGlu: 1.984 ± 0.858
2.976SerPhe: 2.976 ± 1.39
5.952SerGly: 5.952 ± 1.982
3.968SerHis: 3.968 ± 1.716
4.96SerIle: 4.96 ± 1.043
4.96SerLys: 4.96 ± 0.986
2.976SerLeu: 2.976 ± 1.772
1.984SerMet: 1.984 ± 0.858
2.976SerAsn: 2.976 ± 1.39
1.984SerPro: 1.984 ± 1.668
6.944SerGln: 6.944 ± 1.887
6.944SerArg: 6.944 ± 1.282
8.929SerSer: 8.929 ± 1.43
5.952SerThr: 5.952 ± 1.561
4.96SerVal: 4.96 ± 0.986
0.0SerTrp: 0.0 ± 0.0
1.984SerTyr: 1.984 ± 0.858
0.0SerXaa: 0.0 ± 0.0
Thr
3.968ThrAla: 3.968 ± 0.831
0.0ThrCys: 0.0 ± 0.0
4.96ThrAsp: 4.96 ± 1.315
5.952ThrGlu: 5.952 ± 1.052
2.976ThrPhe: 2.976 ± 1.49
3.968ThrGly: 3.968 ± 2.628
0.992ThrHis: 0.992 ± 0.976
2.976ThrIle: 2.976 ± 1.716
11.905ThrLys: 11.905 ± 3.897
7.937ThrLeu: 7.937 ± 1.534
1.984ThrMet: 1.984 ± 0.902
1.984ThrAsn: 1.984 ± 1.953
4.96ThrPro: 4.96 ± 1.86
0.992ThrGln: 0.992 ± 0.769
5.952ThrArg: 5.952 ± 2.574
8.929ThrSer: 8.929 ± 1.789
7.937ThrThr: 7.937 ± 2.828
8.929ThrVal: 8.929 ± 1.858
1.984ThrTrp: 1.984 ± 0.864
5.952ThrTyr: 5.952 ± 1.452
0.0ThrXaa: 0.0 ± 0.0
Val
0.0ValAla: 0.0 ± 0.0
3.968ValCys: 3.968 ± 0.831
3.968ValAsp: 3.968 ± 1.646
0.0ValGlu: 0.0 ± 0.0
0.992ValPhe: 0.992 ± 1.567
1.984ValGly: 1.984 ± 1.74
2.976ValHis: 2.976 ± 1.716
3.968ValIle: 3.968 ± 2.25
2.976ValLys: 2.976 ± 2.346
2.976ValLeu: 2.976 ± 3.164
0.992ValMet: 0.992 ± 1.214
3.968ValAsn: 3.968 ± 1.728
4.96ValPro: 4.96 ± 1.86
0.0ValGln: 0.0 ± 0.0
6.944ValArg: 6.944 ± 1.786
2.976ValSer: 2.976 ± 1.49
5.952ValThr: 5.952 ± 1.561
2.976ValVal: 2.976 ± 2.346
0.0ValTrp: 0.0 ± 0.0
2.976ValTyr: 2.976 ± 1.716
0.0ValXaa: 0.0 ± 0.0
Trp
5.952TrpAla: 5.952 ± 1.452
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
2.976TrpGlu: 2.976 ± 0.477
0.0TrpPhe: 0.0 ± 0.0
1.984TrpGly: 1.984 ± 0.858
0.0TrpHis: 0.0 ± 0.0
1.984TrpIle: 1.984 ± 1.953
1.984TrpLys: 1.984 ± 0.864
1.984TrpLeu: 1.984 ± 0.864
0.0TrpMet: 0.0 ± 0.0
0.992TrpAsn: 0.992 ± 0.725
0.0TrpPro: 0.0 ± 0.0
0.992TrpGln: 0.992 ± 0.976
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
0.992TrpThr: 0.992 ± 0.769
1.984TrpVal: 1.984 ± 1.74
0.992TrpTrp: 0.992 ± 0.769
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.976TyrAla: 2.976 ± 1.459
0.992TyrCys: 0.992 ± 0.725
1.984TyrAsp: 1.984 ± 0.864
0.992TyrGlu: 0.992 ± 0.725
2.976TyrPhe: 2.976 ± 0.477
1.984TyrGly: 1.984 ± 0.864
1.984TyrHis: 1.984 ± 0.858
4.96TyrIle: 4.96 ± 2.193
1.984TyrLys: 1.984 ± 1.953
7.937TyrLeu: 7.937 ± 2.166
1.984TyrMet: 1.984 ± 0.858
2.976TyrAsn: 2.976 ± 1.39
2.976TyrPro: 2.976 ± 1.49
1.984TyrGln: 1.984 ± 0.858
0.0TyrArg: 0.0 ± 0.0
1.984TyrSer: 1.984 ± 0.858
5.952TyrThr: 5.952 ± 1.452
0.992TyrVal: 0.992 ± 0.725
0.992TyrTrp: 0.992 ± 0.725
0.992TyrTyr: 0.992 ± 0.976
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1009 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski