Amino acid dipepetide frequency for Flavipsychrobacter stenotrophus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.107AlaAla: 7.107 ± 0.11	0.841AlaCys: 0.841 ± 0.026	4.331AlaAsp: 4.331 ± 0.056	3.617AlaGlu: 3.617 ± 0.065	3.229AlaPhe: 3.229 ± 0.046	6.986AlaGly: 6.986 ± 0.145	1.428AlaHis: 1.428 ± 0.035	5.748AlaIle: 5.748 ± 0.077	4.119AlaLys: 4.119 ± 0.076	6.405AlaLeu: 6.405 ± 0.079	2.066AlaMet: 2.066 ± 0.043	3.959AlaAsn: 3.959 ± 0.069	2.869AlaPro: 2.869 ± 0.055	2.732AlaGln: 2.732 ± 0.048	2.49AlaArg: 2.49 ± 0.044	5.092AlaSer: 5.092 ± 0.114	6.87AlaThr: 6.87 ± 0.23	5.222AlaVal: 5.222 ± 0.084	0.763AlaTrp: 0.763 ± 0.021	2.967AlaTyr: 2.967 ± 0.046	0.0AlaXaa: 0.0 ± 0.0
Cys	0.873CysAla: 0.873 ± 0.032	0.155CysCys: 0.155 ± 0.012	0.574CysAsp: 0.574 ± 0.019	0.458CysGlu: 0.458 ± 0.019	0.532CysPhe: 0.532 ± 0.019	1.148CysGly: 1.148 ± 0.048	0.243CysHis: 0.243 ± 0.014	0.829CysIle: 0.829 ± 0.026	0.558CysLys: 0.558 ± 0.019	0.92CysLeu: 0.92 ± 0.029	0.282CysMet: 0.282 ± 0.012	0.677CysAsn: 0.677 ± 0.034	0.491CysPro: 0.491 ± 0.025	0.294CysGln: 0.294 ± 0.015	0.403CysArg: 0.403 ± 0.018	0.904CysSer: 0.904 ± 0.031	0.834CysThr: 0.834 ± 0.034	0.742CysVal: 0.742 ± 0.026	0.106CysTrp: 0.106 ± 0.009	0.48CysTyr: 0.48 ± 0.021	0.0CysXaa: 0.0 ± 0.0
Asp	4.107AspAla: 4.107 ± 0.077	0.453AspCys: 0.453 ± 0.02	2.517AspAsp: 2.517 ± 0.051	2.858AspGlu: 2.858 ± 0.065	2.386AspPhe: 2.386 ± 0.044	3.85AspGly: 3.85 ± 0.068	0.977AspHis: 0.977 ± 0.027	3.829AspIle: 3.829 ± 0.057	3.582AspLys: 3.582 ± 0.066	4.064AspLeu: 4.064 ± 0.066	1.441AspMet: 1.441 ± 0.034	2.863AspAsn: 2.863 ± 0.049	1.879AspPro: 1.879 ± 0.038	1.27AspGln: 1.27 ± 0.034	1.878AspArg: 1.878 ± 0.042	3.69AspSer: 3.69 ± 0.069	3.916AspThr: 3.916 ± 0.076	3.407AspVal: 3.407 ± 0.054	0.603AspTrp: 0.603 ± 0.02	2.311AspTyr: 2.311 ± 0.044	0.0AspXaa: 0.0 ± 0.0
Glu	3.452GluAla: 3.452 ± 0.073	0.4GluCys: 0.4 ± 0.02	2.371GluAsp: 2.371 ± 0.056	3.202GluGlu: 3.202 ± 0.078	1.857GluPhe: 1.857 ± 0.047	2.975GluGly: 2.975 ± 0.051	1.16GluHis: 1.16 ± 0.031	3.605GluIle: 3.605 ± 0.069	3.826GluLys: 3.826 ± 0.08	4.829GluLeu: 4.829 ± 0.088	1.524GluMet: 1.524 ± 0.038	2.619GluAsn: 2.619 ± 0.047	1.363GluPro: 1.363 ± 0.032	2.243GluGln: 2.243 ± 0.045	2.244GluArg: 2.244 ± 0.046	2.288GluSer: 2.288 ± 0.043	2.459GluThr: 2.459 ± 0.052	3.358GluVal: 3.358 ± 0.062	0.633GluTrp: 0.633 ± 0.022	2.003GluTyr: 2.003 ± 0.047	0.0GluXaa: 0.0 ± 0.0
Phe	3.281PheAla: 3.281 ± 0.045	0.539PheCys: 0.539 ± 0.02	2.579PheAsp: 2.579 ± 0.046	2.155PheGlu: 2.155 ± 0.048	2.19PhePhe: 2.19 ± 0.048	2.941PheGly: 2.941 ± 0.05	0.799PheHis: 0.799 ± 0.023	3.252PheIle: 3.252 ± 0.067	2.557PheLys: 2.557 ± 0.049	3.546PheLeu: 3.546 ± 0.075	1.095PheMet: 1.095 ± 0.029	2.593PheAsn: 2.593 ± 0.049	1.597PhePro: 1.597 ± 0.036	1.165PheGln: 1.165 ± 0.032	1.735PheArg: 1.735 ± 0.036	3.488PheSer: 3.488 ± 0.049	3.632PheThr: 3.632 ± 0.063	2.804PheVal: 2.804 ± 0.048	0.468PheTrp: 0.468 ± 0.018	1.915PheTyr: 1.915 ± 0.035	0.0PheXaa: 0.0 ± 0.0
Gly	5.701GlyAla: 5.701 ± 0.137	1.073GlyCys: 1.073 ± 0.049	3.612GlyAsp: 3.612 ± 0.06	2.862GlyGlu: 2.862 ± 0.056	3.212GlyPhe: 3.212 ± 0.046	6.094GlyGly: 6.094 ± 0.134	1.315GlyHis: 1.315 ± 0.032	5.61GlyIle: 5.61 ± 0.08	4.547GlyLys: 4.547 ± 0.08	5.683GlyLeu: 5.683 ± 0.066	1.97GlyMet: 1.97 ± 0.038	4.297GlyAsn: 4.297 ± 0.073	1.932GlyPro: 1.932 ± 0.057	1.982GlyGln: 1.982 ± 0.036	2.401GlyArg: 2.401 ± 0.047	5.426GlySer: 5.426 ± 0.152	6.37GlyThr: 6.37 ± 0.233	5.322GlyVal: 5.322 ± 0.09	0.827GlyTrp: 0.827 ± 0.025	3.256GlyTyr: 3.256 ± 0.057	0.0GlyXaa: 0.0 ± 0.0
His	1.262HisAla: 1.262 ± 0.033	0.246HisCys: 0.246 ± 0.011	0.98HisAsp: 0.98 ± 0.026	0.941HisGlu: 0.941 ± 0.025	1.087HisPhe: 1.087 ± 0.029	1.226HisGly: 1.226 ± 0.031	0.546HisHis: 0.546 ± 0.025	1.507HisIle: 1.507 ± 0.033	1.148HisLys: 1.148 ± 0.032	1.748HisLeu: 1.748 ± 0.04	0.475HisMet: 0.475 ± 0.017	1.067HisAsn: 1.067 ± 0.023	1.046HisPro: 1.046 ± 0.029	0.565HisGln: 0.565 ± 0.021	0.718HisArg: 0.718 ± 0.025	1.269HisSer: 1.269 ± 0.029	1.256HisThr: 1.256 ± 0.031	1.176HisVal: 1.176 ± 0.029	0.256HisTrp: 0.256 ± 0.014	0.922HisTyr: 0.922 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	6.175IleAla: 6.175 ± 0.069	0.976IleCys: 0.976 ± 0.031	4.264IleAsp: 4.264 ± 0.062	3.61IleGlu: 3.61 ± 0.073	2.868IlePhe: 2.868 ± 0.06	4.797IleGly: 4.797 ± 0.063	1.349IleHis: 1.349 ± 0.03	5.028IleIle: 5.028 ± 0.082	4.383IleLys: 4.383 ± 0.075	5.532IleLeu: 5.532 ± 0.076	1.495IleMet: 1.495 ± 0.036	4.139IleAsn: 4.139 ± 0.064	3.01IlePro: 3.01 ± 0.047	1.94IleGln: 1.94 ± 0.042	2.67IleArg: 2.67 ± 0.048	5.499IleSer: 5.499 ± 0.074	5.928IleThr: 5.928 ± 0.113	4.73IleVal: 4.73 ± 0.06	0.699IleTrp: 0.699 ± 0.023	2.805IleTyr: 2.805 ± 0.049	0.0IleXaa: 0.0 ± 0.0
Lys	4.386LysAla: 4.386 ± 0.067	0.453LysCys: 0.453 ± 0.022	3.572LysAsp: 3.572 ± 0.073	4.305LysGlu: 4.305 ± 0.08	2.214LysPhe: 2.214 ± 0.047	3.936LysGly: 3.936 ± 0.071	1.274LysHis: 1.274 ± 0.032	4.369LysIle: 4.369 ± 0.072	4.995LysLys: 4.995 ± 0.094	5.109LysLeu: 5.109 ± 0.086	2.104LysMet: 2.104 ± 0.042	3.332LysAsn: 3.332 ± 0.061	2.227LysPro: 2.227 ± 0.046	2.47LysGln: 2.47 ± 0.055	2.479LysArg: 2.479 ± 0.05	3.106LysSer: 3.106 ± 0.053	3.423LysThr: 3.423 ± 0.06	3.996LysVal: 3.996 ± 0.053	0.771LysTrp: 0.771 ± 0.029	2.624LysTyr: 2.624 ± 0.06	0.0LysXaa: 0.0 ± 0.0
Leu	6.414LeuAla: 6.414 ± 0.075	1.084LeuCys: 1.084 ± 0.032	4.06LeuAsp: 4.06 ± 0.059	3.9LeuGlu: 3.9 ± 0.078	4.1LeuPhe: 4.1 ± 0.06	5.339LeuGly: 5.339 ± 0.057	1.81LeuHis: 1.81 ± 0.038	5.457LeuIle: 5.457 ± 0.088	5.455LeuLys: 5.455 ± 0.098	8.56LeuLeu: 8.56 ± 0.127	2.125LeuMet: 2.125 ± 0.041	4.554LeuAsn: 4.554 ± 0.063	3.972LeuPro: 3.972 ± 0.059	3.186LeuGln: 3.186 ± 0.056	3.226LeuArg: 3.226 ± 0.062	6.667LeuSer: 6.667 ± 0.081	5.854LeuThr: 5.854 ± 0.092	5.052LeuVal: 5.052 ± 0.066	0.882LeuTrp: 0.882 ± 0.028	3.279LeuTyr: 3.279 ± 0.051	0.0LeuXaa: 0.0 ± 0.0
Met	2.106MetAla: 2.106 ± 0.042	0.229MetCys: 0.229 ± 0.011	1.292MetAsp: 1.292 ± 0.033	1.35MetGlu: 1.35 ± 0.035	0.904MetPhe: 0.904 ± 0.026	1.773MetGly: 1.773 ± 0.034	0.575MetHis: 0.575 ± 0.021	1.589MetIle: 1.589 ± 0.035	1.997MetLys: 1.997 ± 0.044	2.326MetLeu: 2.326 ± 0.045	0.786MetMet: 0.786 ± 0.027	1.375MetAsn: 1.375 ± 0.029	1.304MetPro: 1.304 ± 0.03	1.108MetGln: 1.108 ± 0.029	1.117MetArg: 1.117 ± 0.028	1.632MetSer: 1.632 ± 0.035	1.454MetThr: 1.454 ± 0.032	1.634MetVal: 1.634 ± 0.031	0.257MetTrp: 0.257 ± 0.014	0.852MetTyr: 0.852 ± 0.024	0.0MetXaa: 0.0 ± 0.0
Asn	4.159AsnAla: 4.159 ± 0.064	0.563AsnCys: 0.563 ± 0.018	2.878AsnAsp: 2.878 ± 0.048	2.736AsnGlu: 2.736 ± 0.051	2.275AsnPhe: 2.275 ± 0.044	4.57AsnGly: 4.57 ± 0.09	0.936AsnHis: 0.936 ± 0.027	4.394AsnIle: 4.394 ± 0.056	3.424AsnLys: 3.424 ± 0.055	4.001AsnLeu: 4.001 ± 0.057	1.427AsnMet: 1.427 ± 0.035	3.547AsnAsn: 3.547 ± 0.059	2.709AsnPro: 2.709 ± 0.056	1.421AsnGln: 1.421 ± 0.033	1.971AsnArg: 1.971 ± 0.037	3.542AsnSer: 3.542 ± 0.069	4.139AsnThr: 4.139 ± 0.098	3.741AsnVal: 3.741 ± 0.056	0.664AsnTrp: 0.664 ± 0.021	2.634AsnTyr: 2.634 ± 0.049	0.0AsnXaa: 0.0 ± 0.0
Pro	3.78ProAla: 3.78 ± 0.057	0.368ProCys: 0.368 ± 0.018	2.409ProAsp: 2.409 ± 0.045	2.194ProGlu: 2.194 ± 0.045	1.869ProPhe: 1.869 ± 0.042	3.031ProGly: 3.031 ± 0.054	0.732ProHis: 0.732 ± 0.024	2.55ProIle: 2.55 ± 0.047	1.797ProLys: 1.797 ± 0.041	3.199ProLeu: 3.199 ± 0.045	0.859ProMet: 0.859 ± 0.025	2.015ProAsn: 2.015 ± 0.039	1.196ProPro: 1.196 ± 0.039	1.199ProGln: 1.199 ± 0.036	1.066ProArg: 1.066 ± 0.025	2.62ProSer: 2.62 ± 0.061	2.79ProThr: 2.79 ± 0.084	3.378ProVal: 3.378 ± 0.06	0.345ProTrp: 0.345 ± 0.014	1.628ProTyr: 1.628 ± 0.038	0.0ProXaa: 0.0 ± 0.0
Gln	2.172GlnAla: 2.172 ± 0.043	0.291GlnCys: 0.291 ± 0.014	1.353GlnAsp: 1.353 ± 0.033	1.503GlnGlu: 1.503 ± 0.038	1.47GlnPhe: 1.47 ± 0.035	1.791GlnGly: 1.791 ± 0.038	0.754GlnHis: 0.754 ± 0.022	2.12GlnIle: 2.12 ± 0.041	2.155GlnLys: 2.155 ± 0.046	3.386GlnLeu: 3.386 ± 0.06	0.973GlnMet: 0.973 ± 0.026	1.682GlnAsn: 1.682 ± 0.035	1.383GlnPro: 1.383 ± 0.034	1.696GlnGln: 1.696 ± 0.05	1.28GlnArg: 1.28 ± 0.036	1.907GlnSer: 1.907 ± 0.036	1.904GlnThr: 1.904 ± 0.037	2.141GlnVal: 2.141 ± 0.039	0.473GlnTrp: 0.473 ± 0.022	1.563GlnTyr: 1.563 ± 0.035	0.0GlnXaa: 0.0 ± 0.0
Arg	2.269ArgAla: 2.269 ± 0.045	0.318ArgCys: 0.318 ± 0.015	1.812ArgAsp: 1.812 ± 0.04	1.94ArgGlu: 1.94 ± 0.041	1.851ArgPhe: 1.851 ± 0.037	1.98ArgGly: 1.98 ± 0.044	0.767ArgHis: 0.767 ± 0.024	2.9ArgIle: 2.9 ± 0.053	2.777ArgLys: 2.777 ± 0.06	3.299ArgLeu: 3.299 ± 0.058	1.16ArgMet: 1.16 ± 0.032	2.118ArgAsn: 2.118 ± 0.045	1.254ArgPro: 1.254 ± 0.029	1.374ArgGln: 1.374 ± 0.037	1.552ArgArg: 1.552 ± 0.037	2.177ArgSer: 2.177 ± 0.041	2.002ArgThr: 2.002 ± 0.041	2.3ArgVal: 2.3 ± 0.044	0.451ArgTrp: 0.451 ± 0.018	1.749ArgTyr: 1.749 ± 0.043	0.0ArgXaa: 0.0 ± 0.0
Ser	5.852SerAla: 5.852 ± 0.131	0.973SerCys: 0.973 ± 0.038	3.13SerAsp: 3.13 ± 0.048	2.596SerGlu: 2.596 ± 0.052	3.551SerPhe: 3.551 ± 0.048	6.374SerGly: 6.374 ± 0.176	1.119SerHis: 1.119 ± 0.027	5.017SerIle: 5.017 ± 0.066	3.368SerLys: 3.368 ± 0.064	5.967SerLeu: 5.967 ± 0.07	1.511SerMet: 1.511 ± 0.033	3.573SerAsn: 3.573 ± 0.07	2.604SerPro: 2.604 ± 0.056	1.732SerGln: 1.732 ± 0.027	2.162SerArg: 2.162 ± 0.043	5.094SerSer: 5.094 ± 0.148	5.049SerThr: 5.049 ± 0.149	5.173SerVal: 5.173 ± 0.093	0.834SerTrp: 0.834 ± 0.031	3.031SerTyr: 3.031 ± 0.051	0.0SerXaa: 0.0 ± 0.0
Thr	6.429ThrAla: 6.429 ± 0.179	0.746ThrCys: 0.746 ± 0.029	3.66ThrAsp: 3.66 ± 0.048	2.885ThrGlu: 2.885 ± 0.049	3.142ThrPhe: 3.142 ± 0.053	7.025ThrGly: 7.025 ± 0.21	1.194ThrHis: 1.194 ± 0.035	5.854ThrIle: 5.854 ± 0.122	2.969ThrLys: 2.969 ± 0.047	6.324ThrLeu: 6.324 ± 0.114	1.4ThrMet: 1.4 ± 0.031	3.802ThrAsn: 3.802 ± 0.091	3.49ThrPro: 3.49 ± 0.098	1.844ThrGln: 1.844 ± 0.039	2.004ThrArg: 2.004 ± 0.039	5.058ThrSer: 5.058 ± 0.152	6.376ThrThr: 6.376 ± 0.236	5.891ThrVal: 5.891 ± 0.192	0.958ThrTrp: 0.958 ± 0.041	3.208ThrTyr: 3.208 ± 0.08	0.0ThrXaa: 0.0 ± 0.0
Val	5.674ValAla: 5.674 ± 0.09	1.106ValCys: 1.106 ± 0.041	3.495ValAsp: 3.495 ± 0.053	2.898ValGlu: 2.898 ± 0.053	2.896ValPhe: 2.896 ± 0.045	4.195ValGly: 4.195 ± 0.067	1.285ValHis: 1.285 ± 0.032	4.73ValIle: 4.73 ± 0.058	4.125ValLys: 4.125 ± 0.059	5.517ValLeu: 5.517 ± 0.064	1.632ValMet: 1.632 ± 0.031	4.103ValAsn: 4.103 ± 0.074	2.694ValPro: 2.694 ± 0.047	1.981ValGln: 1.981 ± 0.035	2.376ValArg: 2.376 ± 0.042	5.081ValSer: 5.081 ± 0.091	5.826ValThr: 5.826 ± 0.181	5.004ValVal: 5.004 ± 0.067	0.79ValTrp: 0.79 ± 0.028	2.933ValTyr: 2.933 ± 0.051	0.0ValXaa: 0.0 ± 0.0
Trp	0.767TrpAla: 0.767 ± 0.023	0.122TrpCys: 0.122 ± 0.009	0.619TrpAsp: 0.619 ± 0.021	0.522TrpGlu: 0.522 ± 0.018	0.508TrpPhe: 0.508 ± 0.021	0.744TrpGly: 0.744 ± 0.022	0.277TrpHis: 0.277 ± 0.015	0.683TrpIle: 0.683 ± 0.024	0.702TrpLys: 0.702 ± 0.024	1.077TrpLeu: 1.077 ± 0.03	0.359TrpMet: 0.359 ± 0.016	0.631TrpAsn: 0.631 ± 0.021	0.293TrpPro: 0.293 ± 0.012	0.475TrpGln: 0.475 ± 0.018	0.477TrpArg: 0.477 ± 0.017	0.962TrpSer: 0.962 ± 0.046	0.793TrpThr: 0.793 ± 0.029	0.772TrpVal: 0.772 ± 0.027	0.173TrpTrp: 0.173 ± 0.011	0.509TrpTyr: 0.509 ± 0.023	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.874TyrAla: 2.874 ± 0.046	0.566TyrCys: 0.566 ± 0.02	2.374TyrAsp: 2.374 ± 0.048	1.879TyrGlu: 1.879 ± 0.044	2.191TyrPhe: 2.191 ± 0.049	2.716TyrGly: 2.716 ± 0.05	0.9TyrHis: 0.9 ± 0.026	2.828TyrIle: 2.828 ± 0.048	2.66TyrLys: 2.66 ± 0.058	3.482TyrLeu: 3.482 ± 0.056	0.975TyrMet: 0.975 ± 0.026	2.786TyrAsn: 2.786 ± 0.059	1.714TyrPro: 1.714 ± 0.034	1.321TyrGln: 1.321 ± 0.032	1.803TyrArg: 1.803 ± 0.035	3.208TyrSer: 3.208 ± 0.068	3.384TyrThr: 3.384 ± 0.082	2.496TyrVal: 2.496 ± 0.042	0.511TyrTrp: 0.511 ± 0.019	2.179TyrTyr: 2.179 ± 0.044	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4474 proteins (1561615 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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