Amino acid dipepetide frequency for Maracuja mosaic virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.946AlaAla: 1.946 ± 0.843
1.46AlaCys: 1.46 ± 0.459
3.406AlaAsp: 3.406 ± 1.318
1.946AlaGlu: 1.946 ± 1.123
1.946AlaPhe: 1.946 ± 0.34
2.92AlaGly: 2.92 ± 1.957
0.0AlaHis: 0.0 ± 0.0
2.433AlaIle: 2.433 ± 1.899
1.46AlaLys: 1.46 ± 0.469
6.326AlaLeu: 6.326 ± 0.944
1.46AlaMet: 1.46 ± 0.469
4.38AlaAsn: 4.38 ± 2.387
0.487AlaPro: 0.487 ± 0.263
1.946AlaGln: 1.946 ± 1.764
1.46AlaArg: 1.46 ± 0.79
5.353AlaSer: 5.353 ± 2.121
2.433AlaThr: 2.433 ± 1.593
4.866AlaVal: 4.866 ± 0.94
0.487AlaTrp: 0.487 ± 0.263
1.46AlaTyr: 1.46 ± 1.568
0.0AlaXaa: 0.0 ± 0.0
Cys
1.46CysAla: 1.46 ± 1.026
0.973CysCys: 0.973 ± 0.561
0.973CysAsp: 0.973 ± 0.667
0.973CysGlu: 0.973 ± 1.046
0.487CysPhe: 0.487 ± 0.523
2.433CysGly: 2.433 ± 0.852
0.0CysHis: 0.0 ± 0.0
0.487CysIle: 0.487 ± 0.523
1.946CysLys: 1.946 ± 0.634
1.946CysLeu: 1.946 ± 1.053
0.973CysMet: 0.973 ± 0.526
1.46CysAsn: 1.46 ± 0.79
0.973CysPro: 0.973 ± 0.526
0.0CysGln: 0.0 ± 0.0
0.973CysArg: 0.973 ± 0.421
0.487CysSer: 0.487 ± 0.523
0.0CysThr: 0.0 ± 0.0
2.433CysVal: 2.433 ± 1.27
0.0CysTrp: 0.0 ± 0.0
0.487CysTyr: 0.487 ± 0.523
0.0CysXaa: 0.0 ± 0.0
Asp
4.38AspAla: 4.38 ± 0.867
0.973AspCys: 0.973 ± 1.046
3.893AspAsp: 3.893 ± 0.361
3.406AspGlu: 3.406 ± 0.537
2.92AspPhe: 2.92 ± 0.939
0.0AspGly: 0.0 ± 0.0
0.0AspHis: 0.0 ± 0.0
3.893AspIle: 3.893 ± 0.884
4.38AspLys: 4.38 ± 0.693
2.433AspLeu: 2.433 ± 0.97
1.46AspMet: 1.46 ± 0.459
1.46AspAsn: 1.46 ± 1.568
2.92AspPro: 2.92 ± 0.811
1.946AspGln: 1.946 ± 0.77
1.46AspArg: 1.46 ± 0.759
4.38AspSer: 4.38 ± 1.278
6.813AspThr: 6.813 ± 2.853
10.706AspVal: 10.706 ± 1.64
0.487AspTrp: 0.487 ± 0.523
2.92AspTyr: 2.92 ± 0.528
0.0AspXaa: 0.0 ± 0.0
Glu
2.433GluAla: 2.433 ± 1.032
1.46GluCys: 1.46 ± 0.469
0.973GluAsp: 0.973 ± 0.526
1.946GluGlu: 1.946 ± 0.843
3.893GluPhe: 3.893 ± 0.666
1.946GluGly: 1.946 ± 1.123
0.487GluHis: 0.487 ± 0.523
3.406GluIle: 3.406 ± 0.521
2.92GluLys: 2.92 ± 0.827
5.839GluLeu: 5.839 ± 1.694
0.487GluMet: 0.487 ± 0.523
2.92GluAsn: 2.92 ± 0.939
1.46GluPro: 1.46 ± 0.62
2.433GluGln: 2.433 ± 1.014
6.813GluArg: 6.813 ± 2.087
5.839GluSer: 5.839 ± 1.958
4.38GluThr: 4.38 ± 1.311
5.353GluVal: 5.353 ± 1.074
0.487GluTrp: 0.487 ± 0.263
2.92GluTyr: 2.92 ± 0.939
0.0GluXaa: 0.0 ± 0.0
Phe
1.46PheAla: 1.46 ± 0.759
1.946PheCys: 1.946 ± 0.809
6.326PheAsp: 6.326 ± 2.106
1.46PheGlu: 1.46 ± 0.759
1.46PhePhe: 1.46 ± 0.912
2.92PheGly: 2.92 ± 0.521
0.973PheHis: 0.973 ± 1.046
3.893PheIle: 3.893 ± 1.664
3.406PheLys: 3.406 ± 1.333
3.406PheLeu: 3.406 ± 0.55
1.46PheMet: 1.46 ± 0.912
1.946PheAsn: 1.946 ± 0.843
2.433PhePro: 2.433 ± 1.032
4.866PheGln: 4.866 ± 1.039
0.487PheArg: 0.487 ± 0.263
5.353PheSer: 5.353 ± 0.964
2.92PheThr: 2.92 ± 1.579
4.38PheVal: 4.38 ± 1.731
0.0PheTrp: 0.0 ± 0.0
0.487PheTyr: 0.487 ± 0.523
0.0PheXaa: 0.0 ± 0.0
Gly
1.946GlyAla: 1.946 ± 0.634
2.92GlyCys: 2.92 ± 1.334
3.893GlyAsp: 3.893 ± 2.852
3.893GlyGlu: 3.893 ± 1.54
1.46GlyPhe: 1.46 ± 0.62
1.946GlyGly: 1.946 ± 0.77
0.487GlyHis: 0.487 ± 0.523
2.433GlyIle: 2.433 ± 0.852
4.38GlyLys: 4.38 ± 1.408
6.813GlyLeu: 6.813 ± 2.192
1.946GlyMet: 1.946 ± 0.366
4.38GlyAsn: 4.38 ± 1.378
2.433GlyPro: 2.433 ± 0.849
0.973GlyGln: 0.973 ± 0.928
1.946GlyArg: 1.946 ± 0.885
2.92GlySer: 2.92 ± 2.218
1.46GlyThr: 1.46 ± 0.469
4.38GlyVal: 4.38 ± 1.774
0.973GlyTrp: 0.973 ± 0.526
0.487GlyTyr: 0.487 ± 0.263
0.0GlyXaa: 0.0 ± 0.0
His
0.487HisAla: 0.487 ± 0.523
0.973HisCys: 0.973 ± 0.421
0.973HisAsp: 0.973 ± 0.421
0.973HisGlu: 0.973 ± 0.421
0.973HisPhe: 0.973 ± 0.421
0.973HisGly: 0.973 ± 0.526
0.0HisHis: 0.0 ± 0.0
0.973HisIle: 0.973 ± 0.526
0.487HisLys: 0.487 ± 0.523
0.487HisLeu: 0.487 ± 0.523
1.46HisMet: 1.46 ± 0.469
0.973HisAsn: 0.973 ± 0.526
0.487HisPro: 0.487 ± 0.62
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
1.46HisSer: 1.46 ± 0.469
1.46HisThr: 1.46 ± 0.79
1.946HisVal: 1.946 ± 1.123
0.0HisTrp: 0.0 ± 0.0
0.487HisTyr: 0.487 ± 0.263
0.0HisXaa: 0.0 ± 0.0
Ile
2.433IleAla: 2.433 ± 1.27
0.0IleCys: 0.0 ± 0.0
0.973IleAsp: 0.973 ± 0.421
3.406IleGlu: 3.406 ± 1.779
1.946IlePhe: 1.946 ± 0.634
3.406IleGly: 3.406 ± 1.084
0.973IleHis: 0.973 ± 0.561
1.946IleIle: 1.946 ± 1.069
4.866IleLys: 4.866 ± 2.615
5.839IleLeu: 5.839 ± 1.042
0.0IleMet: 0.0 ± 0.0
3.406IleAsn: 3.406 ± 1.394
2.433IlePro: 2.433 ± 0.849
4.38IleGln: 4.38 ± 0.879
4.38IleArg: 4.38 ± 1.464
3.406IleSer: 3.406 ± 0.853
4.38IleThr: 4.38 ± 1.332
3.406IleVal: 3.406 ± 0.537
0.973IleTrp: 0.973 ± 0.421
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
3.893LysAla: 3.893 ± 1.624
0.487LysCys: 0.487 ± 0.263
3.893LysAsp: 3.893 ± 1.058
4.38LysGlu: 4.38 ± 0.859
2.433LysPhe: 2.433 ± 0.97
5.839LysGly: 5.839 ± 2.28
1.46LysHis: 1.46 ± 0.469
4.866LysIle: 4.866 ± 1.214
4.38LysLys: 4.38 ± 1.185
5.839LysLeu: 5.839 ± 1.309
1.46LysMet: 1.46 ± 1.338
2.433LysAsn: 2.433 ± 0.911
2.433LysPro: 2.433 ± 0.627
2.92LysGln: 2.92 ± 1.334
4.38LysArg: 4.38 ± 1.185
1.946LysSer: 1.946 ± 1.486
3.893LysThr: 3.893 ± 0.884
3.893LysVal: 3.893 ± 2.106
0.0LysTrp: 0.0 ± 0.0
1.46LysTyr: 1.46 ± 1.026
0.0LysXaa: 0.0 ± 0.0
Leu
2.433LeuAla: 2.433 ± 0.627
0.973LeuCys: 0.973 ± 0.421
5.839LeuAsp: 5.839 ± 1.572
4.38LeuGlu: 4.38 ± 1.378
3.406LeuPhe: 3.406 ± 1.847
3.893LeuGly: 3.893 ± 0.68
0.0LeuHis: 0.0 ± 0.0
2.92LeuIle: 2.92 ± 1.579
7.299LeuLys: 7.299 ± 1.06
7.786LeuLeu: 7.786 ± 0.747
3.406LeuMet: 3.406 ± 0.802
6.326LeuAsn: 6.326 ± 0.785
4.38LeuPro: 4.38 ± 0.637
3.893LeuGln: 3.893 ± 0.666
9.246LeuArg: 9.246 ± 1.227
5.839LeuSer: 5.839 ± 1.167
6.326LeuThr: 6.326 ± 1.439
7.786LeuVal: 7.786 ± 1.049
0.973LeuTrp: 0.973 ± 1.046
2.92LeuTyr: 2.92 ± 0.939
0.0LeuXaa: 0.0 ± 0.0
Met
0.973MetAla: 0.973 ± 0.561
0.487MetCys: 0.487 ± 0.62
1.946MetAsp: 1.946 ± 0.34
1.46MetGlu: 1.46 ± 0.62
0.0MetPhe: 0.0 ± 0.0
0.487MetGly: 0.487 ± 0.62
0.487MetHis: 0.487 ± 0.263
2.92MetIle: 2.92 ± 1.825
2.433MetLys: 2.433 ± 0.627
1.946MetLeu: 1.946 ± 1.006
1.946MetMet: 1.946 ± 0.77
0.0MetAsn: 0.0 ± 0.0
1.46MetPro: 1.46 ± 1.065
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
1.946MetSer: 1.946 ± 0.77
1.46MetThr: 1.46 ± 0.79
0.973MetVal: 0.973 ± 0.561
0.0MetTrp: 0.0 ± 0.0
0.973MetTyr: 0.973 ± 0.526
0.0MetXaa: 0.0 ± 0.0
Asn
3.406AsnAla: 3.406 ± 2.833
0.973AsnCys: 0.973 ± 0.421
2.92AsnAsp: 2.92 ± 1.445
4.38AsnGlu: 4.38 ± 1.476
5.353AsnPhe: 5.353 ± 1.752
3.893AsnGly: 3.893 ± 1.31
1.46AsnHis: 1.46 ± 0.79
1.46AsnIle: 1.46 ± 0.469
0.487AsnLys: 0.487 ± 0.263
2.433AsnLeu: 2.433 ± 1.282
0.487AsnMet: 0.487 ± 0.62
0.973AsnAsn: 0.973 ± 0.667
2.433AsnPro: 2.433 ± 1.607
0.487AsnGln: 0.487 ± 0.62
2.433AsnArg: 2.433 ± 1.014
3.893AsnSer: 3.893 ± 0.934
3.406AsnThr: 3.406 ± 0.951
5.839AsnVal: 5.839 ± 1.939
0.973AsnTrp: 0.973 ± 0.746
3.406AsnTyr: 3.406 ± 2.174
0.0AsnXaa: 0.0 ± 0.0
Pro
2.92ProAla: 2.92 ± 0.743
1.46ProCys: 1.46 ± 0.469
2.92ProAsp: 2.92 ± 0.939
4.866ProGlu: 4.866 ± 1.121
1.46ProPhe: 1.46 ± 0.79
2.92ProGly: 2.92 ± 0.939
0.973ProHis: 0.973 ± 0.421
2.433ProIle: 2.433 ± 0.649
3.406ProLys: 3.406 ± 2.174
2.433ProLeu: 2.433 ± 2.36
0.0ProMet: 0.0 ± 0.0
1.46ProAsn: 1.46 ± 1.859
2.433ProPro: 2.433 ± 0.399
0.973ProGln: 0.973 ± 0.526
0.973ProArg: 0.973 ± 0.421
2.92ProSer: 2.92 ± 1.872
2.433ProThr: 2.433 ± 0.97
4.866ProVal: 4.866 ± 1.705
0.487ProTrp: 0.487 ± 0.823
1.46ProTyr: 1.46 ± 0.759
0.0ProXaa: 0.0 ± 0.0
Gln
1.946GlnAla: 1.946 ± 0.885
0.973GlnCys: 0.973 ± 0.526
2.92GlnAsp: 2.92 ± 0.827
1.46GlnGlu: 1.46 ± 0.459
0.973GlnPhe: 0.973 ± 0.526
1.946GlnGly: 1.946 ± 0.885
0.487GlnHis: 0.487 ± 0.263
2.92GlnIle: 2.92 ± 1.194
0.487GlnLys: 0.487 ± 0.263
4.866GlnLeu: 4.866 ± 1.05
0.973GlnMet: 0.973 ± 0.526
1.946GlnAsn: 1.946 ± 1.006
1.946GlnPro: 1.946 ± 1.069
0.973GlnGln: 0.973 ± 0.526
2.92GlnArg: 2.92 ± 1.264
3.893GlnSer: 3.893 ± 1.685
1.946GlnThr: 1.946 ± 1.526
2.92GlnVal: 2.92 ± 2.239
0.0GlnTrp: 0.0 ± 0.0
0.973GlnTyr: 0.973 ± 0.526
0.0GlnXaa: 0.0 ± 0.0
Arg
3.406ArgAla: 3.406 ± 0.853
1.946ArgCys: 1.946 ± 0.634
1.946ArgAsp: 1.946 ± 0.856
2.433ArgGlu: 2.433 ± 0.399
4.866ArgPhe: 4.866 ± 1.413
1.46ArgGly: 1.46 ± 0.62
0.973ArgHis: 0.973 ± 0.421
1.46ArgIle: 1.46 ± 1.815
2.92ArgLys: 2.92 ± 0.919
6.326ArgLeu: 6.326 ± 1.147
0.973ArgMet: 0.973 ± 0.561
2.433ArgAsn: 2.433 ± 0.649
1.46ArgPro: 1.46 ± 0.469
1.46ArgGln: 1.46 ± 0.62
4.866ArgArg: 4.866 ± 1.162
6.326ArgSer: 6.326 ± 1.636
5.353ArgThr: 5.353 ± 0.525
5.353ArgVal: 5.353 ± 1.956
0.973ArgTrp: 0.973 ± 0.561
0.0ArgTyr: 0.0 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
4.866SerAla: 4.866 ± 2.862
0.0SerCys: 0.0 ± 0.0
3.406SerAsp: 3.406 ± 1.406
4.38SerGlu: 4.38 ± 1.774
4.38SerPhe: 4.38 ± 0.985
4.38SerGly: 4.38 ± 1.036
1.946SerHis: 1.946 ± 0.634
2.92SerIle: 2.92 ± 0.528
4.866SerLys: 4.866 ± 1.911
8.273SerLeu: 8.273 ± 1.463
0.973SerMet: 0.973 ± 0.561
6.813SerAsn: 6.813 ± 1.526
3.406SerPro: 3.406 ± 1.08
3.406SerGln: 3.406 ± 0.789
4.38SerArg: 4.38 ± 1.311
2.92SerSer: 2.92 ± 1.264
4.38SerThr: 4.38 ± 1.109
5.353SerVal: 5.353 ± 1.009
0.973SerTrp: 0.973 ± 0.561
3.406SerTyr: 3.406 ± 1.333
0.0SerXaa: 0.0 ± 0.0
Thr
1.46ThrAla: 1.46 ± 0.459
0.487ThrCys: 0.487 ± 0.263
2.92ThrAsp: 2.92 ± 1.872
5.353ThrGlu: 5.353 ± 2.39
4.38ThrPhe: 4.38 ± 1.84
4.38ThrGly: 4.38 ± 0.31
0.487ThrHis: 0.487 ± 0.263
4.866ThrIle: 4.866 ± 0.58
5.353ThrLys: 5.353 ± 2.39
3.893ThrLeu: 3.893 ± 1.311
0.487ThrMet: 0.487 ± 0.62
1.946ThrAsn: 1.946 ± 0.34
3.893ThrPro: 3.893 ± 1.058
1.46ThrGln: 1.46 ± 0.759
3.406ThrArg: 3.406 ± 1.2
4.866ThrSer: 4.866 ± 1.282
3.406ThrThr: 3.406 ± 1.084
7.299ThrVal: 7.299 ± 1.196
0.973ThrTrp: 0.973 ± 0.746
3.893ThrTyr: 3.893 ± 1.585
0.0ThrXaa: 0.0 ± 0.0
Val
4.866ValAla: 4.866 ± 1.256
0.973ValCys: 0.973 ± 0.561
6.813ValAsp: 6.813 ± 1.919
5.353ValGlu: 5.353 ± 1.859
6.813ValPhe: 6.813 ± 0.647
3.893ValGly: 3.893 ± 2.012
3.406ValHis: 3.406 ± 1.432
3.893ValIle: 3.893 ± 0.68
5.353ValLys: 5.353 ± 3.378
8.759ValLeu: 8.759 ± 2.206
0.487ValMet: 0.487 ± 0.263
3.893ValAsn: 3.893 ± 1.712
4.38ValPro: 4.38 ± 1.109
2.92ValGln: 2.92 ± 1.518
4.38ValArg: 4.38 ± 1.454
8.273ValSer: 8.273 ± 1.387
5.353ValThr: 5.353 ± 0.666
7.299ValVal: 7.299 ± 1.992
2.433ValTrp: 2.433 ± 0.649
3.406ValTyr: 3.406 ± 1.2
0.0ValXaa: 0.0 ± 0.0
Trp
0.487TrpAla: 0.487 ± 0.823
0.0TrpCys: 0.0 ± 0.0
0.487TrpAsp: 0.487 ± 0.263
0.973TrpGlu: 0.973 ± 0.421
1.46TrpPhe: 1.46 ± 0.759
0.973TrpGly: 0.973 ± 0.526
0.487TrpHis: 0.487 ± 0.62
0.487TrpIle: 0.487 ± 0.263
0.0TrpLys: 0.0 ± 0.0
0.973TrpLeu: 0.973 ± 0.421
0.0TrpMet: 0.0 ± 0.0
0.973TrpAsn: 0.973 ± 0.421
0.0TrpPro: 0.0 ± 0.0
0.487TrpGln: 0.487 ± 0.263
0.487TrpArg: 0.487 ± 0.523
1.46TrpSer: 1.46 ± 0.459
0.487TrpThr: 0.487 ± 0.263
1.46TrpVal: 1.46 ± 1.549
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.973TyrAla: 0.973 ± 0.421
0.0TyrCys: 0.0 ± 0.0
3.406TyrAsp: 3.406 ± 0.789
0.973TyrGlu: 0.973 ± 0.526
0.973TyrPhe: 0.973 ± 1.046
1.46TyrGly: 1.46 ± 0.469
0.487TyrHis: 0.487 ± 0.523
1.946TyrIle: 1.946 ± 0.843
1.946TyrLys: 1.946 ± 0.809
3.406TyrLeu: 3.406 ± 0.813
0.973TyrMet: 0.973 ± 0.561
0.973TyrAsn: 0.973 ± 0.526
1.946TyrPro: 1.946 ± 0.634
1.946TyrGln: 1.946 ± 1.526
1.946TyrArg: 1.946 ± 0.634
1.946TyrSer: 1.946 ± 1.006
2.92TyrThr: 2.92 ± 1.825
2.433TyrVal: 2.433 ± 0.97
0.487TyrTrp: 0.487 ± 0.263
1.46TyrTyr: 1.46 ± 0.469
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (2056 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski