Amino acid dipepetide frequency for Monilinia fructicola (Brown rot fungus) (Ciboria fructicola)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.355AlaAla: 7.355 ± 0.057	0.915AlaCys: 0.915 ± 0.014	3.542AlaAsp: 3.542 ± 0.027	4.733AlaGlu: 4.733 ± 0.036	2.814AlaPhe: 2.814 ± 0.026	5.168AlaGly: 5.168 ± 0.039	1.614AlaHis: 1.614 ± 0.019	4.268AlaIle: 4.268 ± 0.037	4.083AlaLys: 4.083 ± 0.04	6.71AlaLeu: 6.71 ± 0.041	1.768AlaMet: 1.768 ± 0.019	2.941AlaAsn: 2.941 ± 0.027	4.513AlaPro: 4.513 ± 0.045	3.087AlaGln: 3.087 ± 0.03	4.288AlaArg: 4.288 ± 0.032	6.887AlaSer: 6.887 ± 0.047	4.897AlaThr: 4.897 ± 0.037	4.408AlaVal: 4.408 ± 0.03	0.982AlaTrp: 0.982 ± 0.015	1.97AlaTyr: 1.97 ± 0.023	0.0AlaXaa: 0.0 ± 0.0
Cys	0.84CysAla: 0.84 ± 0.013	0.253CysCys: 0.253 ± 0.008	0.609CysAsp: 0.609 ± 0.009	0.598CysGlu: 0.598 ± 0.01	0.542CysPhe: 0.542 ± 0.01	0.922CysGly: 0.922 ± 0.016	0.325CysHis: 0.325 ± 0.008	0.754CysIle: 0.754 ± 0.014	0.564CysLys: 0.564 ± 0.012	1.2CysLeu: 1.2 ± 0.016	0.288CysMet: 0.288 ± 0.007	0.455CysAsn: 0.455 ± 0.01	0.62CysPro: 0.62 ± 0.012	0.427CysGln: 0.427 ± 0.009	0.668CysArg: 0.668 ± 0.011	0.948CysSer: 0.948 ± 0.015	0.71CysThr: 0.71 ± 0.013	0.726CysVal: 0.726 ± 0.012	0.202CysTrp: 0.202 ± 0.006	0.356CysTyr: 0.356 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	4.047AspAla: 4.047 ± 0.028	0.588AspCys: 0.588 ± 0.011	4.224AspAsp: 4.224 ± 0.044	4.613AspGlu: 4.613 ± 0.043	2.158AspPhe: 2.158 ± 0.021	3.981AspGly: 3.981 ± 0.028	1.167AspHis: 1.167 ± 0.015	3.23AspIle: 3.23 ± 0.025	2.32AspLys: 2.32 ± 0.025	4.78AspLeu: 4.78 ± 0.031	1.221AspMet: 1.221 ± 0.017	1.993AspAsn: 1.993 ± 0.02	2.962AspPro: 2.962 ± 0.026	1.758AspGln: 1.758 ± 0.018	2.756AspArg: 2.756 ± 0.028	4.145AspSer: 4.145 ± 0.033	2.875AspThr: 2.875 ± 0.021	3.323AspVal: 3.323 ± 0.024	0.816AspTrp: 0.816 ± 0.013	1.509AspTyr: 1.509 ± 0.018	0.0AspXaa: 0.0 ± 0.0
Glu	4.923GluAla: 4.923 ± 0.037	0.611GluCys: 0.611 ± 0.01	4.385GluAsp: 4.385 ± 0.038	6.245GluGlu: 6.245 ± 0.064	2.012GluPhe: 2.012 ± 0.02	4.042GluGly: 4.042 ± 0.035	1.297GluHis: 1.297 ± 0.017	3.547GluIle: 3.547 ± 0.029	4.382GluLys: 4.382 ± 0.043	5.022GluLeu: 5.022 ± 0.04	1.602GluMet: 1.602 ± 0.016	2.763GluAsn: 2.763 ± 0.023	2.632GluPro: 2.632 ± 0.042	2.313GluGln: 2.313 ± 0.026	4.215GluArg: 4.215 ± 0.041	4.598GluSer: 4.598 ± 0.046	3.379GluThr: 3.379 ± 0.028	3.711GluVal: 3.711 ± 0.034	0.873GluTrp: 0.873 ± 0.013	1.735GluTyr: 1.735 ± 0.02	0.0GluXaa: 0.0 ± 0.0
Phe	2.772PheAla: 2.772 ± 0.028	0.575PheCys: 0.575 ± 0.011	2.202PheAsp: 2.202 ± 0.024	2.225PheGlu: 2.225 ± 0.026	1.621PhePhe: 1.621 ± 0.022	2.839PheGly: 2.839 ± 0.034	0.958PheHis: 0.958 ± 0.015	1.955PheIle: 1.955 ± 0.022	1.646PheLys: 1.646 ± 0.019	3.417PheLeu: 3.417 ± 0.028	0.813PheMet: 0.813 ± 0.013	1.539PheAsn: 1.539 ± 0.019	2.008PhePro: 2.008 ± 0.021	1.404PheGln: 1.404 ± 0.017	1.805PheArg: 1.805 ± 0.017	3.184PheSer: 3.184 ± 0.026	2.23PheThr: 2.23 ± 0.021	2.193PheVal: 2.193 ± 0.02	0.599PheTrp: 0.599 ± 0.011	1.093PheTyr: 1.093 ± 0.014	0.0PheXaa: 0.0 ± 0.0
Gly	4.859GlyAla: 4.859 ± 0.04	0.858GlyCys: 0.858 ± 0.014	3.519GlyAsp: 3.519 ± 0.031	3.963GlyGlu: 3.963 ± 0.035	2.72GlyPhe: 2.72 ± 0.027	6.125GlyGly: 6.125 ± 0.068	1.557GlyHis: 1.557 ± 0.019	3.725GlyIle: 3.725 ± 0.03	3.826GlyLys: 3.826 ± 0.028	5.614GlyLeu: 5.614 ± 0.039	1.703GlyMet: 1.703 ± 0.02	2.901GlyAsn: 2.901 ± 0.03	3.001GlyPro: 3.001 ± 0.029	2.261GlyGln: 2.261 ± 0.025	4.044GlyArg: 4.044 ± 0.032	5.802GlySer: 5.802 ± 0.044	3.939GlyThr: 3.939 ± 0.03	4.236GlyVal: 4.236 ± 0.029	1.169GlyTrp: 1.169 ± 0.016	2.133GlyTyr: 2.133 ± 0.024	0.0GlyXaa: 0.0 ± 0.0
His	1.653HisAla: 1.653 ± 0.02	0.336HisCys: 0.336 ± 0.009	1.279HisAsp: 1.279 ± 0.015	1.32HisGlu: 1.32 ± 0.017	0.927HisPhe: 0.927 ± 0.013	1.614HisGly: 1.614 ± 0.016	0.95HisHis: 0.95 ± 0.017	1.335HisIle: 1.335 ± 0.016	1.029HisLys: 1.029 ± 0.013	2.233HisLeu: 2.233 ± 0.022	0.48HisMet: 0.48 ± 0.009	0.976HisAsn: 0.976 ± 0.013	1.749HisPro: 1.749 ± 0.02	1.06HisGln: 1.06 ± 0.017	1.465HisArg: 1.465 ± 0.017	2.034HisSer: 2.034 ± 0.019	1.427HisThr: 1.427 ± 0.017	1.28HisVal: 1.28 ± 0.014	0.303HisTrp: 0.303 ± 0.008	0.69HisTyr: 0.69 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	4.117IleAla: 4.117 ± 0.03	0.816IleCys: 0.816 ± 0.015	3.052IleAsp: 3.052 ± 0.024	3.305IleGlu: 3.305 ± 0.028	2.213IlePhe: 2.213 ± 0.024	3.391IleGly: 3.391 ± 0.032	1.455IleHis: 1.455 ± 0.017	3.057IleIle: 3.057 ± 0.028	2.695IleLys: 2.695 ± 0.025	4.956IleLeu: 4.956 ± 0.037	1.16IleMet: 1.16 ± 0.015	2.267IleAsn: 2.267 ± 0.021	3.625IlePro: 3.625 ± 0.027	2.109IleGln: 2.109 ± 0.022	2.873IleArg: 2.873 ± 0.025	4.812IleSer: 4.812 ± 0.031	3.27IleThr: 3.27 ± 0.026	3.183IleVal: 3.183 ± 0.026	0.766IleTrp: 0.766 ± 0.012	1.612IleTyr: 1.612 ± 0.018	0.0IleXaa: 0.0 ± 0.0
Lys	4.256LysAla: 4.256 ± 0.037	0.556LysCys: 0.556 ± 0.012	3.044LysAsp: 3.044 ± 0.026	4.001LysGlu: 4.001 ± 0.04	1.65LysPhe: 1.65 ± 0.019	3.345LysGly: 3.345 ± 0.03	1.194LysHis: 1.194 ± 0.016	2.844LysIle: 2.844 ± 0.026	4.146LysLys: 4.146 ± 0.046	4.332LysLeu: 4.332 ± 0.03	1.185LysMet: 1.185 ± 0.016	2.24LysAsn: 2.24 ± 0.023	2.834LysPro: 2.834 ± 0.025	1.865LysGln: 1.865 ± 0.02	3.667LysArg: 3.667 ± 0.032	4.334LysSer: 4.334 ± 0.036	3.096LysThr: 3.096 ± 0.026	3.064LysVal: 3.064 ± 0.026	0.716LysTrp: 0.716 ± 0.013	1.503LysTyr: 1.503 ± 0.016	0.0LysXaa: 0.0 ± 0.0
Leu	6.811LeuAla: 6.811 ± 0.043	1.143LeuCys: 1.143 ± 0.016	4.689LeuAsp: 4.689 ± 0.035	5.446LeuGlu: 5.446 ± 0.038	3.215LeuPhe: 3.215 ± 0.029	5.617LeuGly: 5.617 ± 0.037	2.182LeuHis: 2.182 ± 0.022	4.211LeuIle: 4.211 ± 0.034	4.547LeuLys: 4.547 ± 0.032	7.837LeuLeu: 7.837 ± 0.056	1.755LeuMet: 1.755 ± 0.021	3.408LeuAsn: 3.408 ± 0.027	5.453LeuPro: 5.453 ± 0.037	3.637LeuGln: 3.637 ± 0.031	5.181LeuArg: 5.181 ± 0.04	7.394LeuSer: 7.394 ± 0.045	4.675LeuThr: 4.675 ± 0.036	4.789LeuVal: 4.789 ± 0.039	1.079LeuTrp: 1.079 ± 0.016	2.284LeuTyr: 2.284 ± 0.024	0.0LeuXaa: 0.0 ± 0.0
Met	1.995MetAla: 1.995 ± 0.018	0.238MetCys: 0.238 ± 0.006	1.315MetAsp: 1.315 ± 0.017	1.435MetGlu: 1.435 ± 0.015	0.749MetPhe: 0.749 ± 0.012	1.572MetGly: 1.572 ± 0.019	0.511MetHis: 0.511 ± 0.01	1.168MetIle: 1.168 ± 0.017	1.204MetLys: 1.204 ± 0.015	1.716MetLeu: 1.716 ± 0.019	0.649MetMet: 0.649 ± 0.012	0.964MetAsn: 0.964 ± 0.015	1.156MetPro: 1.156 ± 0.016	0.873MetGln: 0.873 ± 0.015	1.274MetArg: 1.274 ± 0.014	1.913MetSer: 1.913 ± 0.019	1.305MetThr: 1.305 ± 0.018	1.287MetVal: 1.287 ± 0.018	0.239MetTrp: 0.239 ± 0.007	0.527MetTyr: 0.527 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	3.148AsnAla: 3.148 ± 0.024	0.473AsnCys: 0.473 ± 0.01	2.164AsnAsp: 2.164 ± 0.022	2.367AsnGlu: 2.367 ± 0.024	1.594AsnPhe: 1.594 ± 0.018	3.31AsnGly: 3.31 ± 0.033	1.076AsnHis: 1.076 ± 0.015	2.486AsnIle: 2.486 ± 0.022	1.883AsnLys: 1.883 ± 0.02	3.601AsnLeu: 3.601 ± 0.029	0.939AsnMet: 0.939 ± 0.014	1.906AsnAsn: 1.906 ± 0.025	2.697AsnPro: 2.697 ± 0.023	1.556AsnGln: 1.556 ± 0.02	2.096AsnArg: 2.096 ± 0.021	3.563AsnSer: 3.563 ± 0.028	2.691AsnThr: 2.691 ± 0.027	2.341AsnVal: 2.341 ± 0.021	0.564AsnTrp: 0.564 ± 0.01	1.194AsnTyr: 1.194 ± 0.017	0.0AsnXaa: 0.0 ± 0.0
Pro	4.545ProAla: 4.545 ± 0.043	0.505ProCys: 0.505 ± 0.012	2.719ProAsp: 2.719 ± 0.026	3.565ProGlu: 3.565 ± 0.034	2.041ProPhe: 2.041 ± 0.02	3.499ProGly: 3.499 ± 0.029	1.401ProHis: 1.401 ± 0.016	3.116ProIle: 3.116 ± 0.027	2.972ProLys: 2.972 ± 0.028	4.659ProLeu: 4.659 ± 0.034	1.064ProMet: 1.064 ± 0.013	2.523ProAsn: 2.523 ± 0.023	5.144ProPro: 5.144 ± 0.056	2.574ProGln: 2.574 ± 0.032	3.348ProArg: 3.348 ± 0.031	6.459ProSer: 6.459 ± 0.052	4.283ProThr: 4.283 ± 0.043	3.192ProVal: 3.192 ± 0.03	0.644ProTrp: 0.644 ± 0.011	1.53ProTyr: 1.53 ± 0.02	0.0ProXaa: 0.0 ± 0.0
Gln	3.069GlnAla: 3.069 ± 0.03	0.416GlnCys: 0.416 ± 0.009	1.913GlnAsp: 1.913 ± 0.022	2.415GlnGlu: 2.415 ± 0.027	1.267GlnPhe: 1.267 ± 0.017	2.252GlnGly: 2.252 ± 0.023	1.069GlnHis: 1.069 ± 0.017	2.096GlnIle: 2.096 ± 0.022	2.227GlnLys: 2.227 ± 0.021	3.131GlnLeu: 3.131 ± 0.028	0.862GlnMet: 0.862 ± 0.013	1.832GlnAsn: 1.832 ± 0.02	2.297GlnPro: 2.297 ± 0.028	2.323GlnGln: 2.323 ± 0.056	2.451GlnArg: 2.451 ± 0.022	3.377GlnSer: 3.377 ± 0.032	2.312GlnThr: 2.312 ± 0.022	2.007GlnVal: 2.007 ± 0.02	0.515GlnTrp: 0.515 ± 0.01	1.217GlnTyr: 1.217 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	4.122ArgAla: 4.122 ± 0.028	0.676ArgCys: 0.676 ± 0.013	3.133ArgAsp: 3.133 ± 0.031	4.041ArgGlu: 4.041 ± 0.035	1.994ArgPhe: 1.994 ± 0.018	3.818ArgGly: 3.818 ± 0.036	1.425ArgHis: 1.425 ± 0.016	3.046ArgIle: 3.046 ± 0.025	3.772ArgLys: 3.772 ± 0.031	4.816ArgLeu: 4.816 ± 0.036	1.318ArgMet: 1.318 ± 0.016	2.489ArgAsn: 2.489 ± 0.023	3.158ArgPro: 3.158 ± 0.03	2.34ArgGln: 2.34 ± 0.021	4.847ArgArg: 4.847 ± 0.043	4.857ArgSer: 4.857 ± 0.042	3.129ArgThr: 3.129 ± 0.026	3.082ArgVal: 3.082 ± 0.027	0.825ArgTrp: 0.825 ± 0.014	1.615ArgTyr: 1.615 ± 0.018	0.0ArgXaa: 0.0 ± 0.0
Ser	6.304SerAla: 6.304 ± 0.047	0.934SerCys: 0.934 ± 0.015	4.166SerAsp: 4.166 ± 0.032	4.415SerGlu: 4.415 ± 0.038	3.313SerPhe: 3.313 ± 0.026	5.603SerGly: 5.603 ± 0.043	2.185SerHis: 2.185 ± 0.025	5.004SerIle: 5.004 ± 0.036	4.466SerLys: 4.466 ± 0.036	7.361SerLeu: 7.361 ± 0.05	1.826SerMet: 1.826 ± 0.021	3.842SerAsn: 3.842 ± 0.032	5.94SerPro: 5.94 ± 0.048	3.496SerGln: 3.496 ± 0.036	5.082SerArg: 5.082 ± 0.032	10.417SerSer: 10.417 ± 0.107	6.538SerThr: 6.538 ± 0.05	4.361SerVal: 4.361 ± 0.036	1.067SerTrp: 1.067 ± 0.015	2.297SerTyr: 2.297 ± 0.022	0.0SerXaa: 0.0 ± 0.0
Thr	4.705ThrAla: 4.705 ± 0.031	0.73ThrCys: 0.73 ± 0.013	2.63ThrAsp: 2.63 ± 0.024	3.139ThrGlu: 3.139 ± 0.028	2.361ThrPhe: 2.361 ± 0.018	4.041ThrGly: 4.041 ± 0.031	1.393ThrHis: 1.393 ± 0.017	3.583ThrIle: 3.583 ± 0.024	2.979ThrLys: 2.979 ± 0.023	5.193ThrLeu: 5.193 ± 0.038	1.213ThrMet: 1.213 ± 0.016	2.521ThrAsn: 2.521 ± 0.024	4.638ThrPro: 4.638 ± 0.038	2.167ThrGln: 2.167 ± 0.021	3.086ThrArg: 3.086 ± 0.029	6.287ThrSer: 6.287 ± 0.049	4.736ThrThr: 4.736 ± 0.052	3.36ThrVal: 3.36 ± 0.025	0.779ThrTrp: 0.779 ± 0.013	1.728ThrTyr: 1.728 ± 0.021	0.0ThrXaa: 0.0 ± 0.0
Val	4.477ValAla: 4.477 ± 0.033	0.758ValCys: 0.758 ± 0.011	3.391ValAsp: 3.391 ± 0.028	4.036ValGlu: 4.036 ± 0.034	2.216ValPhe: 2.216 ± 0.022	3.842ValGly: 3.842 ± 0.031	1.261ValHis: 1.261 ± 0.016	2.957ValIle: 2.957 ± 0.026	3.044ValLys: 3.044 ± 0.026	4.948ValLeu: 4.948 ± 0.033	1.27ValMet: 1.27 ± 0.016	2.2ValAsn: 2.2 ± 0.02	3.278ValPro: 3.278 ± 0.025	2.148ValGln: 2.148 ± 0.02	2.97ValArg: 2.97 ± 0.027	4.375ValSer: 4.375 ± 0.03	3.268ValThr: 3.268 ± 0.026	3.897ValVal: 3.897 ± 0.031	0.787ValTrp: 0.787 ± 0.014	1.576ValTyr: 1.576 ± 0.019	0.0ValXaa: 0.0 ± 0.0
Trp	0.956TrpAla: 0.956 ± 0.014	0.201TrpCys: 0.201 ± 0.007	0.841TrpAsp: 0.841 ± 0.013	0.85TrpGlu: 0.85 ± 0.013	0.488TrpPhe: 0.488 ± 0.009	0.941TrpGly: 0.941 ± 0.014	0.329TrpHis: 0.329 ± 0.008	0.798TrpIle: 0.798 ± 0.013	0.832TrpLys: 0.832 ± 0.012	1.193TrpLeu: 1.193 ± 0.014	0.4TrpMet: 0.4 ± 0.009	0.637TrpAsn: 0.637 ± 0.012	0.516TrpPro: 0.516 ± 0.01	0.492TrpGln: 0.492 ± 0.01	0.88TrpArg: 0.88 ± 0.013	1.016TrpSer: 1.016 ± 0.015	0.793TrpThr: 0.793 ± 0.013	0.785TrpVal: 0.785 ± 0.012	0.258TrpTrp: 0.258 ± 0.007	0.392TrpTyr: 0.392 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.991TyrAla: 1.991 ± 0.021	0.425TyrCys: 0.425 ± 0.01	1.648TyrAsp: 1.648 ± 0.019	1.576TyrGlu: 1.576 ± 0.019	1.182TyrPhe: 1.182 ± 0.015	2.032TyrGly: 2.032 ± 0.025	0.79TyrHis: 0.79 ± 0.013	1.552TyrIle: 1.552 ± 0.018	1.254TyrLys: 1.254 ± 0.018	2.636TyrLeu: 2.636 ± 0.024	0.572TyrMet: 0.572 ± 0.011	1.252TyrAsn: 1.252 ± 0.017	1.56TyrPro: 1.56 ± 0.021	1.158TyrGln: 1.158 ± 0.016	1.51TyrArg: 1.51 ± 0.018	2.218TyrSer: 2.218 ± 0.021	1.715TyrThr: 1.715 ± 0.02	1.476TyrVal: 1.476 ± 0.017	0.414TyrTrp: 0.414 ± 0.008	0.943TyrTyr: 0.943 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 13749 proteins (5524529 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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