Amino acid dipepetide frequency for Massilia timonae CCUG 45783

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.799AlaAla: 17.799 ± 0.169	1.323AlaCys: 1.323 ± 0.033	6.351AlaAsp: 6.351 ± 0.067	6.286AlaGlu: 6.286 ± 0.066	4.07AlaPhe: 4.07 ± 0.047	10.985AlaGly: 10.985 ± 0.103	2.625AlaHis: 2.625 ± 0.042	5.7AlaIle: 5.7 ± 0.067	3.578AlaLys: 3.578 ± 0.067	14.351AlaLeu: 14.351 ± 0.127	3.416AlaMet: 3.416 ± 0.046	3.338AlaAsn: 3.338 ± 0.047	6.763AlaPro: 6.763 ± 0.079	5.166AlaGln: 5.166 ± 0.062	9.641AlaArg: 9.641 ± 0.097	6.985AlaSer: 6.985 ± 0.064	6.08AlaThr: 6.08 ± 0.062	8.375AlaVal: 8.375 ± 0.086	1.939AlaTrp: 1.939 ± 0.04	2.591AlaTyr: 2.591 ± 0.041	0.0AlaXaa: 0.0 ± 0.0
Cys	1.231CysAla: 1.231 ± 0.032	0.11CysCys: 0.11 ± 0.009	0.509CysAsp: 0.509 ± 0.016	0.456CysGlu: 0.456 ± 0.015	0.3CysPhe: 0.3 ± 0.014	0.892CysGly: 0.892 ± 0.023	0.229CysHis: 0.229 ± 0.011	0.405CysIle: 0.405 ± 0.016	0.204CysLys: 0.204 ± 0.011	0.806CysLeu: 0.806 ± 0.027	0.192CysMet: 0.192 ± 0.01	0.21CysAsn: 0.21 ± 0.011	0.399CysPro: 0.399 ± 0.018	0.253CysGln: 0.253 ± 0.012	0.556CysArg: 0.556 ± 0.02	0.484CysSer: 0.484 ± 0.019	0.412CysThr: 0.412 ± 0.017	0.606CysVal: 0.606 ± 0.018	0.125CysTrp: 0.125 ± 0.01	0.206CysTyr: 0.206 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	7.359AspAla: 7.359 ± 0.068	0.445AspCys: 0.445 ± 0.016	3.173AspAsp: 3.173 ± 0.048	3.301AspGlu: 3.301 ± 0.048	2.108AspPhe: 2.108 ± 0.035	5.309AspGly: 5.309 ± 0.067	1.123AspHis: 1.123 ± 0.026	2.597AspIle: 2.597 ± 0.042	1.965AspLys: 1.965 ± 0.038	5.395AspLeu: 5.395 ± 0.065	1.334AspMet: 1.334 ± 0.029	1.493AspAsn: 1.493 ± 0.03	3.145AspPro: 3.145 ± 0.046	1.763AspGln: 1.763 ± 0.034	3.379AspArg: 3.379 ± 0.044	2.443AspSer: 2.443 ± 0.038	2.644AspThr: 2.644 ± 0.035	4.164AspVal: 4.164 ± 0.05	0.959AspTrp: 0.959 ± 0.024	1.655AspTyr: 1.655 ± 0.032	0.0AspXaa: 0.0 ± 0.0
Glu	6.517GluAla: 6.517 ± 0.07	0.362GluCys: 0.362 ± 0.016	2.295GluAsp: 2.295 ± 0.037	2.849GluGlu: 2.849 ± 0.052	1.817GluPhe: 1.817 ± 0.034	3.903GluGly: 3.903 ± 0.049	1.419GluHis: 1.419 ± 0.026	2.755GluIle: 2.755 ± 0.038	1.917GluLys: 1.917 ± 0.043	6.134GluLeu: 6.134 ± 0.074	1.318GluMet: 1.318 ± 0.027	1.411GluAsn: 1.411 ± 0.031	2.393GluPro: 2.393 ± 0.042	2.731GluGln: 2.731 ± 0.038	5.119GluArg: 5.119 ± 0.068	2.476GluSer: 2.476 ± 0.039	2.672GluThr: 2.672 ± 0.037	3.852GluVal: 3.852 ± 0.053	0.762GluTrp: 0.762 ± 0.021	1.184GluTyr: 1.184 ± 0.028	0.0GluXaa: 0.0 ± 0.0
Phe	4.205PheAla: 4.205 ± 0.051	0.389PheCys: 0.389 ± 0.017	2.6PheAsp: 2.6 ± 0.038	1.934PheGlu: 1.934 ± 0.04	1.324PhePhe: 1.324 ± 0.029	3.427PheGly: 3.427 ± 0.043	0.759PheHis: 0.759 ± 0.022	1.551PheIle: 1.551 ± 0.034	1.154PheLys: 1.154 ± 0.029	3.032PheLeu: 3.032 ± 0.039	0.855PheMet: 0.855 ± 0.021	1.203PheAsn: 1.203 ± 0.027	1.469PhePro: 1.469 ± 0.026	1.049PheGln: 1.049 ± 0.023	1.903PheArg: 1.903 ± 0.031	2.181PheSer: 2.181 ± 0.039	1.99PheThr: 1.99 ± 0.038	2.692PheVal: 2.692 ± 0.042	0.483PheTrp: 0.483 ± 0.017	0.961PheTyr: 0.961 ± 0.025	0.0PheXaa: 0.0 ± 0.0
Gly	10.308GlyAla: 10.308 ± 0.098	0.806GlyCys: 0.806 ± 0.025	4.19GlyAsp: 4.19 ± 0.05	4.517GlyGlu: 4.517 ± 0.055	3.28GlyPhe: 3.28 ± 0.043	7.05GlyGly: 7.05 ± 0.083	1.878GlyHis: 1.878 ± 0.035	4.121GlyIle: 4.121 ± 0.053	3.586GlyLys: 3.586 ± 0.053	8.368GlyLeu: 8.368 ± 0.077	2.461GlyMet: 2.461 ± 0.039	2.427GlyAsn: 2.427 ± 0.048	3.099GlyPro: 3.099 ± 0.046	3.282GlyGln: 3.282 ± 0.046	5.653GlyArg: 5.653 ± 0.063	4.588GlySer: 4.588 ± 0.056	4.079GlyThr: 4.079 ± 0.058	6.382GlyVal: 6.382 ± 0.071	1.425GlyTrp: 1.425 ± 0.033	2.428GlyTyr: 2.428 ± 0.041	0.0GlyXaa: 0.0 ± 0.0
His	2.964HisAla: 2.964 ± 0.049	0.253HisCys: 0.253 ± 0.014	1.331HisAsp: 1.331 ± 0.03	1.229HisGlu: 1.229 ± 0.03	0.862HisPhe: 0.862 ± 0.021	2.222HisGly: 2.222 ± 0.04	0.644HisHis: 0.644 ± 0.019	0.918HisIle: 0.918 ± 0.026	0.573HisLys: 0.573 ± 0.019	2.208HisLeu: 2.208 ± 0.035	0.49HisMet: 0.49 ± 0.017	0.533HisAsn: 0.533 ± 0.021	1.402HisPro: 1.402 ± 0.03	0.722HisGln: 0.722 ± 0.022	1.411HisArg: 1.411 ± 0.033	1.04HisSer: 1.04 ± 0.023	1.063HisThr: 1.063 ± 0.028	1.496HisVal: 1.496 ± 0.032	0.347HisTrp: 0.347 ± 0.014	0.676HisTyr: 0.676 ± 0.02	0.0HisXaa: 0.0 ± 0.0
Ile	6.142IleAla: 6.142 ± 0.067	0.359IleCys: 0.359 ± 0.014	3.474IleAsp: 3.474 ± 0.045	3.154IleGlu: 3.154 ± 0.043	1.232IlePhe: 1.232 ± 0.029	4.467IleGly: 4.467 ± 0.056	0.887IleHis: 0.887 ± 0.021	1.616IleIle: 1.616 ± 0.034	1.571IleLys: 1.571 ± 0.033	3.779IleLeu: 3.779 ± 0.06	0.904IleMet: 0.904 ± 0.026	1.477IleAsn: 1.477 ± 0.028	2.142IlePro: 2.142 ± 0.035	1.19IleGln: 1.19 ± 0.027	2.704IleArg: 2.704 ± 0.04	2.382IleSer: 2.382 ± 0.041	2.369IleThr: 2.369 ± 0.038	3.836IleVal: 3.836 ± 0.044	0.453IleTrp: 0.453 ± 0.017	0.99IleTyr: 0.99 ± 0.023	0.0IleXaa: 0.0 ± 0.0
Lys	3.721LysAla: 3.721 ± 0.06	0.166LysCys: 0.166 ± 0.009	1.765LysAsp: 1.765 ± 0.038	1.775LysGlu: 1.775 ± 0.035	1.016LysPhe: 1.016 ± 0.027	2.411LysGly: 2.411 ± 0.041	0.729LysHis: 0.729 ± 0.022	1.595LysIle: 1.595 ± 0.033	1.428LysLys: 1.428 ± 0.037	3.52LysLeu: 3.52 ± 0.047	0.866LysMet: 0.866 ± 0.023	1.148LysAsn: 1.148 ± 0.028	2.109LysPro: 2.109 ± 0.044	1.251LysGln: 1.251 ± 0.03	2.339LysArg: 2.339 ± 0.041	1.692LysSer: 1.692 ± 0.035	1.873LysThr: 1.873 ± 0.041	2.529LysVal: 2.529 ± 0.042	0.352LysTrp: 0.352 ± 0.013	0.763LysTyr: 0.763 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	14.987LeuAla: 14.987 ± 0.134	0.931LeuCys: 0.931 ± 0.027	6.5LeuAsp: 6.5 ± 0.072	5.603LeuGlu: 5.603 ± 0.071	3.49LeuPhe: 3.49 ± 0.049	8.297LeuGly: 8.297 ± 0.086	2.3LeuHis: 2.3 ± 0.04	3.891LeuIle: 3.891 ± 0.064	3.449LeuLys: 3.449 ± 0.049	10.782LeuLeu: 10.782 ± 0.121	2.313LeuMet: 2.313 ± 0.038	2.767LeuAsn: 2.767 ± 0.04	5.871LeuPro: 5.871 ± 0.065	3.586LeuGln: 3.586 ± 0.048	7.883LeuArg: 7.883 ± 0.089	5.816LeuSer: 5.816 ± 0.061	5.012LeuThr: 5.012 ± 0.057	7.803LeuVal: 7.803 ± 0.082	1.135LeuTrp: 1.135 ± 0.034	2.239LeuTyr: 2.239 ± 0.037	0.0LeuXaa: 0.0 ± 0.0
Met	2.977MetAla: 2.977 ± 0.045	0.161MetCys: 0.161 ± 0.01	1.16MetAsp: 1.16 ± 0.031	1.108MetGlu: 1.108 ± 0.026	0.809MetPhe: 0.809 ± 0.023	1.696MetGly: 1.696 ± 0.039	0.568MetHis: 0.568 ± 0.017	1.058MetIle: 1.058 ± 0.029	1.04MetLys: 1.04 ± 0.025	2.739MetLeu: 2.739 ± 0.045	0.635MetMet: 0.635 ± 0.024	0.947MetAsn: 0.947 ± 0.022	1.501MetPro: 1.501 ± 0.026	1.052MetGln: 1.052 ± 0.026	1.903MetArg: 1.903 ± 0.036	1.554MetSer: 1.554 ± 0.029	1.553MetThr: 1.553 ± 0.029	1.691MetVal: 1.691 ± 0.036	0.227MetTrp: 0.227 ± 0.012	0.491MetTyr: 0.491 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	3.52AsnAla: 3.52 ± 0.048	0.247AsnCys: 0.247 ± 0.011	1.53AsnAsp: 1.53 ± 0.033	1.391AsnGlu: 1.391 ± 0.029	0.992AsnPhe: 0.992 ± 0.026	2.65AsnGly: 2.65 ± 0.048	0.608AsnHis: 0.608 ± 0.02	1.371AsnIle: 1.371 ± 0.029	0.977AsnLys: 0.977 ± 0.023	2.88AsnLeu: 2.88 ± 0.038	0.675AsnMet: 0.675 ± 0.019	0.996AsnAsn: 0.996 ± 0.033	1.943AsnPro: 1.943 ± 0.036	0.968AsnGln: 0.968 ± 0.026	1.911AsnArg: 1.911 ± 0.034	1.29AsnSer: 1.29 ± 0.029	1.538AsnThr: 1.538 ± 0.038	2.221AsnVal: 2.221 ± 0.04	0.419AsnTrp: 0.419 ± 0.017	0.816AsnTyr: 0.816 ± 0.025	0.0AsnXaa: 0.0 ± 0.0
Pro	7.068ProAla: 7.068 ± 0.076	0.339ProCys: 0.339 ± 0.015	3.446ProAsp: 3.446 ± 0.051	3.261ProGlu: 3.261 ± 0.047	1.776ProPhe: 1.776 ± 0.036	4.845ProGly: 4.845 ± 0.064	1.112ProHis: 1.112 ± 0.024	1.961ProIle: 1.961 ± 0.04	1.47ProLys: 1.47 ± 0.032	5.089ProLeu: 5.089 ± 0.054	1.147ProMet: 1.147 ± 0.027	1.461ProAsn: 1.461 ± 0.034	2.501ProPro: 2.501 ± 0.046	2.045ProGln: 2.045 ± 0.035	2.867ProArg: 2.867 ± 0.046	2.704ProSer: 2.704 ± 0.041	2.386ProThr: 2.386 ± 0.038	4.134ProVal: 4.134 ± 0.058	0.663ProTrp: 0.663 ± 0.019	1.173ProTyr: 1.173 ± 0.028	0.0ProXaa: 0.0 ± 0.0
Gln	5.243GlnAla: 5.243 ± 0.064	0.25GlnCys: 0.25 ± 0.014	1.83GlnAsp: 1.83 ± 0.031	1.84GlnGlu: 1.84 ± 0.037	1.246GlnPhe: 1.246 ± 0.028	2.721GlnGly: 2.721 ± 0.044	0.85GlnHis: 0.85 ± 0.028	1.637GlnIle: 1.637 ± 0.033	1.097GlnLys: 1.097 ± 0.026	4.052GlnLeu: 4.052 ± 0.053	0.951GlnMet: 0.951 ± 0.025	0.956GlnAsn: 0.956 ± 0.023	2.1GlnPro: 2.1 ± 0.032	1.854GlnGln: 1.854 ± 0.044	3.031GlnArg: 3.031 ± 0.044	1.832GlnSer: 1.832 ± 0.039	1.671GlnThr: 1.671 ± 0.033	2.985GlnVal: 2.985 ± 0.045	0.484GlnTrp: 0.484 ± 0.019	0.864GlnTyr: 0.864 ± 0.023	0.0GlnXaa: 0.0 ± 0.0
Arg	8.27ArgAla: 8.27 ± 0.088	0.557ArgCys: 0.557 ± 0.021	4.001ArgAsp: 4.001 ± 0.047	4.157ArgGlu: 4.157 ± 0.063	2.85ArgPhe: 2.85 ± 0.041	4.65ArgGly: 4.65 ± 0.056	1.934ArgHis: 1.934 ± 0.033	3.821ArgIle: 3.821 ± 0.039	2.284ArgLys: 2.284 ± 0.033	7.943ArgLeu: 7.943 ± 0.088	2.091ArgMet: 2.091 ± 0.036	2.053ArgAsn: 2.053 ± 0.036	3.234ArgPro: 3.234 ± 0.048	3.062ArgGln: 3.062 ± 0.052	5.318ArgArg: 5.318 ± 0.073	3.578ArgSer: 3.578 ± 0.049	3.273ArgThr: 3.273 ± 0.045	4.853ArgVal: 4.853 ± 0.059	1.061ArgTrp: 1.061 ± 0.026	2.018ArgTyr: 2.018 ± 0.04	0.0ArgXaa: 0.0 ± 0.0
Ser	6.112SerAla: 6.112 ± 0.063	0.439SerCys: 0.439 ± 0.017	2.642SerAsp: 2.642 ± 0.037	2.538SerGlu: 2.538 ± 0.04	2.059SerPhe: 2.059 ± 0.036	5.252SerGly: 5.252 ± 0.063	1.217SerHis: 1.217 ± 0.026	2.543SerIle: 2.543 ± 0.041	1.655SerLys: 1.655 ± 0.034	5.528SerLeu: 5.528 ± 0.071	1.395SerMet: 1.395 ± 0.029	1.616SerAsn: 1.616 ± 0.037	2.704SerPro: 2.704 ± 0.044	1.824SerGln: 1.824 ± 0.031	3.406SerArg: 3.406 ± 0.044	3.369SerSer: 3.369 ± 0.055	2.955SerThr: 2.955 ± 0.039	3.802SerVal: 3.802 ± 0.044	0.778SerTrp: 0.778 ± 0.025	1.417SerTyr: 1.417 ± 0.031	0.0SerXaa: 0.0 ± 0.0
Thr	5.638ThrAla: 5.638 ± 0.062	0.398ThrCys: 0.398 ± 0.015	2.478ThrAsp: 2.478 ± 0.036	2.293ThrGlu: 2.293 ± 0.039	1.801ThrPhe: 1.801 ± 0.037	4.659ThrGly: 4.659 ± 0.062	1.05ThrHis: 1.05 ± 0.025	2.526ThrIle: 2.526 ± 0.04	1.307ThrLys: 1.307 ± 0.032	5.838ThrLeu: 5.838 ± 0.058	1.216ThrMet: 1.216 ± 0.025	1.348ThrAsn: 1.348 ± 0.034	3.298ThrPro: 3.298 ± 0.042	1.683ThrGln: 1.683 ± 0.035	3.44ThrArg: 3.44 ± 0.042	2.686ThrSer: 2.686 ± 0.043	2.822ThrThr: 2.822 ± 0.047	4.351ThrVal: 4.351 ± 0.061	0.67ThrTrp: 0.67 ± 0.019	1.197ThrTyr: 1.197 ± 0.032	0.0ThrXaa: 0.0 ± 0.0
Val	9.335ValAla: 9.335 ± 0.085	0.663ValCys: 0.663 ± 0.017	4.394ValAsp: 4.394 ± 0.052	4.326ValGlu: 4.326 ± 0.058	2.615ValPhe: 2.615 ± 0.043	5.439ValGly: 5.439 ± 0.061	1.532ValHis: 1.532 ± 0.031	3.453ValIle: 3.453 ± 0.046	2.531ValLys: 2.531 ± 0.043	7.783ValLeu: 7.783 ± 0.076	1.748ValMet: 1.748 ± 0.037	2.312ValAsn: 2.312 ± 0.038	3.555ValPro: 3.555 ± 0.042	2.445ValGln: 2.445 ± 0.04	5.332ValArg: 5.332 ± 0.052	4.059ValSer: 4.059 ± 0.046	4.255ValThr: 4.255 ± 0.056	5.852ValVal: 5.852 ± 0.068	0.863ValTrp: 0.863 ± 0.026	1.691ValTyr: 1.691 ± 0.03	0.0ValXaa: 0.0 ± 0.0
Trp	1.155TrpAla: 1.155 ± 0.029	0.14TrpCys: 0.14 ± 0.009	0.686TrpAsp: 0.686 ± 0.019	0.611TrpGlu: 0.611 ± 0.02	0.555TrpPhe: 0.555 ± 0.018	0.872TrpGly: 0.872 ± 0.022	0.372TrpHis: 0.372 ± 0.016	0.714TrpIle: 0.714 ± 0.024	0.506TrpLys: 0.506 ± 0.017	1.807TrpLeu: 1.807 ± 0.035	0.39TrpMet: 0.39 ± 0.017	0.496TrpAsn: 0.496 ± 0.017	0.593TrpPro: 0.593 ± 0.019	0.652TrpGln: 0.652 ± 0.019	1.231TrpArg: 1.231 ± 0.03	0.806TrpSer: 0.806 ± 0.022	0.71TrpThr: 0.71 ± 0.022	0.868TrpVal: 0.868 ± 0.026	0.236TrpTrp: 0.236 ± 0.012	0.369TrpTyr: 0.369 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.814TyrAla: 2.814 ± 0.041	0.245TyrCys: 0.245 ± 0.012	1.398TyrAsp: 1.398 ± 0.031	1.255TyrGlu: 1.255 ± 0.03	0.959TyrPhe: 0.959 ± 0.027	2.178TyrGly: 2.178 ± 0.034	0.548TyrHis: 0.548 ± 0.018	0.897TyrIle: 0.897 ± 0.024	0.758TyrLys: 0.758 ± 0.024	2.62TyrLeu: 2.62 ± 0.044	0.473TyrMet: 0.473 ± 0.018	0.751TyrAsn: 0.751 ± 0.025	1.225TyrPro: 1.225 ± 0.023	0.918TyrGln: 0.918 ± 0.022	1.981TyrArg: 1.981 ± 0.038	1.286TyrSer: 1.286 ± 0.03	1.342TyrThr: 1.342 ± 0.03	1.693TyrVal: 1.693 ± 0.029	0.388TyrTrp: 0.388 ± 0.013	0.714TyrTyr: 0.714 ± 0.023	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5096 proteins (1765012 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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